<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article PUBLIC "-//NLM//DTD Journal Publishing DTD v2.0 20040830//EN" "journalpublishing.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" dtd-version="2.0" xml:lang="en" article-type="review-article"><front><journal-meta><journal-id journal-id-type="nlm-ta">J Med Internet Res</journal-id><journal-id journal-id-type="publisher-id">jmir</journal-id><journal-id journal-id-type="index">1</journal-id><journal-title>Journal of Medical Internet Research</journal-title><abbrev-journal-title>J Med Internet Res</abbrev-journal-title><issn pub-type="epub">1438-8871</issn><publisher><publisher-name>JMIR Publications</publisher-name><publisher-loc>Toronto, Canada</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">v28i1e83072</article-id><article-id pub-id-type="doi">10.2196/83072</article-id><article-categories><subj-group subj-group-type="heading"><subject>Review</subject></subj-group></article-categories><title-group><article-title>Use of Mobile Technologies for Smoking Cessation Among Smokers and Former Smokers: Systematic Review</article-title></title-group><contrib-group><contrib contrib-type="author"><name name-style="western"><surname>Lakeberg</surname><given-names>Meret</given-names></name><degrees>MSc</degrees><xref ref-type="aff" rid="aff1">1</xref><xref ref-type="aff" rid="aff2">2</xref></contrib><contrib contrib-type="author"><name name-style="western"><surname>Hoffmann</surname><given-names>Falk</given-names></name><degrees>Prof Dr</degrees><xref ref-type="aff" rid="aff1">1</xref><xref ref-type="aff" rid="aff2">2</xref></contrib><contrib contrib-type="author"><name name-style="western"><surname>Ohmes</surname><given-names>Jannik</given-names></name><degrees>BSc</degrees><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib contrib-type="author"><name name-style="western"><surname>Berger-H&#x00F6;ger</surname><given-names>Birte</given-names></name><degrees>Prof Dr</degrees><xref ref-type="aff" rid="aff2">2</xref><xref ref-type="aff" rid="aff3">3</xref></contrib><contrib contrib-type="author" corresp="yes"><name name-style="western"><surname>Helbach</surname><given-names>Jasmin</given-names></name><degrees>Dr rer medic</degrees><xref ref-type="aff" rid="aff1">1</xref></contrib></contrib-group><aff id="aff1"><institution>Department of Health Services Research, School of Medicine and Health Sciences, Carl von Ossietzky Universit&#x00E4;t Oldenburg</institution><addr-line>Ammerl&#x00E4;nder Heerstra&#x00DF;e 114-118</addr-line><addr-line>Oldenburg</addr-line><country>Germany</country></aff><aff id="aff2"><institution>Leibniz Science Campus, Digital Public Health Bremen</institution><addr-line>Bremen</addr-line><country>Germany</country></aff><aff id="aff3"><institution>Faculty 11 Human and Health Sciences, University of Bremen, Institute for Public Health and Nursing Research</institution><addr-line>Bremen</addr-line><country>Germany</country></aff><contrib-group><contrib contrib-type="editor"><name name-style="western"><surname>Brini</surname><given-names>Stefano</given-names></name></contrib></contrib-group><contrib-group><contrib contrib-type="reviewer"><name name-style="western"><surname>Cha</surname><given-names>Sarah</given-names></name></contrib><contrib contrib-type="reviewer"><name name-style="western"><surname>McIntosh</surname><given-names>Scott</given-names></name></contrib></contrib-group><author-notes><corresp>Correspondence to Jasmin Helbach, Dr rer medic, Department of Health Services Research, School of Medicine and Health Sciences, Carl von Ossietzky Universit&#x00E4;t Oldenburg, Ammerl&#x00E4;nder Heerstra&#x00DF;e 114-118, Oldenburg, 26129, Germany, +49 441 798 2206; <email>jasmin.helbach@uni-oldenburg.de</email></corresp></author-notes><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>30</day><month>4</month><year>2026</year></pub-date><volume>28</volume><elocation-id>e83072</elocation-id><history><date date-type="received"><day>29</day><month>08</month><year>2025</year></date><date date-type="rev-recd"><day>26</day><month>01</month><year>2026</year></date><date date-type="accepted"><day>27</day><month>01</month><year>2026</year></date></history><copyright-statement>&#x00A9; Meret Lakeberg, Falk Hoffmann, Jannik Ohmes, Birte Berger-H&#x00F6;ger, Jasmin Helbach. Originally published in the Journal of Medical Internet Research (<ext-link ext-link-type="uri" xlink:href="https://www.jmir.org">https://www.jmir.org</ext-link>), 30.4.2026. </copyright-statement><copyright-year>2026</copyright-year><license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/"><p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (<ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by/4.0/">https://creativecommons.org/licenses/by/4.0/</ext-link>), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Journal of Medical Internet Research (ISSN 1438-8871), is properly cited. The complete bibliographic information, a link to the original publication on <ext-link ext-link-type="uri" xlink:href="https://www.jmir.org/">https://www.jmir.org/</ext-link>, as well as this copyright and license information must be included.</p></license><self-uri xlink:type="simple" xlink:href="https://www.jmir.org/2026/1/e83072"/><abstract><sec><title>Background</title><p>In an era of widespread mobile phone usage, digital public health interventions offer a new cost-effective way of improving public health. In the context of smoking cessation, studies indicate that mobile technologies have the potential to support individuals to quit smoking. However, there is no systematic synthesis of how often they are used by smokers and former smokers.</p></sec><sec><title>Objective</title><p>The aim of this study is to assess the prevalence of mobile technology use for smoking cessation among smokers and former smokers and to examine their intention to use.</p></sec><sec sec-type="methods"><title>Methods</title><p>MEDLINE via PubMed, Embase, and PsycInfo were searched from inception to February 13, 2025. Studies were eligible if they reported how often smokers and former smokers in high-income countries used mobile technologies for smoking or vaping cessation. Study quality was assessed using the Joanna Briggs Institute tool for prevalence studies. Data synthesis was conducted narratively.</p></sec><sec sec-type="results"><title>Results</title><p>Twenty-seven cross-sectional studies were included, 25 on smoking and 2 on vaping cessation. The 25 studies on smoking cessation collected data between 2005 and 2024 and comprised 117 to 27,323 participants (mean age 19.9&#x2010;50.3 years; n=8). Lifetime prevalences of mobile technology use for smoking cessation ranged between 2.5% and 35.9% (n=8), depending on technology type and population. Period prevalences (0%&#x2010;12%; n=4) and point prevalences (1.1%&#x2010;10.9%; n=11) were generally lower. Regardless of the prevalence type, the internet was the most frequently used technology (0.8%&#x2010;35.9%; n=14). Intention to use mobile technologies for smoking cessation ranged from 19.5% for Twitter to 46.7% for websites (n=2). Of the 2 studies on vaping cessation, 1 presented lifetime prevalence (1.1%&#x2010;17.3%), while the other presented period prevalence (5.5%&#x2010;6.3%). The intention to use mobile technologies for vaping cessation ranged from 9.7% for web-based programs to 34.6% for apps (n=1). Based on the risk of bias assessment, study quality was heterogeneous, with frequent limitations in sampling procedures, reporting, and reliance on self-reported measures.</p></sec><sec sec-type="conclusions"><title>Conclusions</title><p>This review provides novel insights into the role of mobile technologies in smoking cessation. Evidence indicates that the prevalence of mobile technology use for smoking cessation is low and that disparities in access and engagement exist. However, there is a high intention to use such tools. Therefore, efforts should focus on delivering existing evidence-based tools rather than developing new ones. Included studies were characterized by high methodological variability and poor reporting, so the results must be interpreted with caution. Overall, despite the widespread availability of mobile technologies to support smoking cessation, research on their utilization remains limited.</p></sec><sec><title>Trial Registration</title><p>PROSPERO CRD42025647875; https://www.crd.york.ac.uk/PROSPERO/view/CRD42025647875</p></sec></abstract><kwd-group><kwd>smoking cessation</kwd><kwd>mHealth</kwd><kwd>digital health</kwd><kwd>quitting smoking</kwd><kwd>tobacco</kwd></kwd-group></article-meta></front><body><sec id="s1" sec-type="intro"><title>Introduction</title><p>Tobacco consumption remains the leading preventable cause of disease, disability, and death worldwide, placing a substantial burden on public health systems [<xref ref-type="bibr" rid="ref1">1</xref>]. Despite decades of prevention efforts, smoking tobacco continues to claim millions of lives each year. The <italic>Global Burden of Disease Study 2019</italic> reported 7.69 million smoking-attributable deaths and over 200 million disability-adjusted life years, with 86.9% of these deaths occurring among current smokers [<xref ref-type="bibr" rid="ref2">2</xref>]. According to the World Health Organization (WHO) <italic>Tobacco Trends Report 2025</italic>, approximately 1 in 5 adults globally still use tobacco [<xref ref-type="bibr" rid="ref3">3</xref>]. While smoking prevalence has steadily declined since the 1960s, particularly in high-income countries [<xref ref-type="bibr" rid="ref4">4</xref>,<xref ref-type="bibr" rid="ref5">5</xref>], the absolute number of smokers remains high. In Europe, the recent smoking prevalence ranges from 8% in Sweden up to 36% in Greece [<xref ref-type="bibr" rid="ref6">6</xref>]. Furthermore, the emergence of new tobacco products and technologies, such as electronic cigarettes (e-cigarettes), has led to a new era of nicotine dependency [<xref ref-type="bibr" rid="ref1">1</xref>]. In 2025, the WHO published its first estimate of the global prevalence of e-cigarettes, indicating that more than 100 million individuals worldwide were currently vaping [<xref ref-type="bibr" rid="ref3">3</xref>].</p><p>Smoking cessation interventions play a key role in the prevention of smoking-related diseases. In 2022, approximately two-thirds of smokers in the United States expressed an intention to quit, and about half of all smokers had made at least 1 quit attempt [<xref ref-type="bibr" rid="ref7">7</xref>]. Unaided quit attempts resulted in long-term abstinence (6&#x2010;12 mo) in approximately 3% to 5% of cases, whereas the use of evidence-based support&#x2014;such as behavioral counseling combined with nicotine replacement therapy, bupropion, or varenicline&#x2014;can increase success rates by an additional 7% to 9% [<xref ref-type="bibr" rid="ref8">8</xref>]. In Germany, data from the DEBRA study (Deutsche Befragung zum Rauchverhalten) show that smoking cessation attempts are common, but only 13% of individuals trying to quit in 2016 to 2019 used at least one evidence-based method [<xref ref-type="bibr" rid="ref9">9</xref>]. This underlines a persistent gap between available evidence-based interventions and their real-world uptake.</p><p>In an era characterized by the widespread use of mobile phones among the global population, with over 82% of individuals above the age of 10 years owning a mobile phone, and a proportion exceeding 95% in high-income countries [<xref ref-type="bibr" rid="ref10">10</xref>], digital public health interventions offer a new scalable, user-friendly, and cost-effective approach to enhancing public health [<xref ref-type="bibr" rid="ref11">11</xref>,<xref ref-type="bibr" rid="ref12">12</xref>], particularly in the domains of prevention and health promotion. In recent years, there has been an increasing integration of digital intervention modalities, encompassing mobile apps, SMS text messaging services, and other web-based interventions, into public health strategies [<xref ref-type="bibr" rid="ref13">13</xref>-<xref ref-type="bibr" rid="ref15">15</xref>], including strategies focusing on smoking cessation [<xref ref-type="bibr" rid="ref16">16</xref>]. The effectiveness of digital smoking cessation interventions has been examined in numerous systematic reviews, which have indicated a promising role for mobile technologies in promoting smoking cessation and abstinence [<xref ref-type="bibr" rid="ref17">17</xref>-<xref ref-type="bibr" rid="ref22">22</xref>]. A systematic review examining the cessation of vaping has also demonstrated the efficacy of digital interventions [<xref ref-type="bibr" rid="ref23">23</xref>]. However, there are no systematic reviews examining the prevalence of the utilization of such aids by smokers and former smokers. Nevertheless, existing evidence shows substantial variability in the prevalence of mobile technology use for smoking cessation across technology types and countries [<xref ref-type="bibr" rid="ref24">24</xref>-<xref ref-type="bibr" rid="ref26">26</xref>]. In an analysis of 8 European countries, Papadakis et al [<xref ref-type="bibr" rid="ref25">25</xref>] reported mobile app use ranging from 0% to 6.2% and use of internet-based resources from 0.75% to 10.2%. Furthermore, user characteristics, including age, sex, and socioeconomic status, appear to be associated with differences in the uptake and engagement with mobile smoking cessation technologies [<xref ref-type="bibr" rid="ref26">26</xref>-<xref ref-type="bibr" rid="ref30">30</xref>]. In order to fully exploit the potential of mobile smoking cessation interventions to support behavior change, it is first necessary to systematically synthesize all existing evidence on how often smokers and former smokers use these tools.</p><p>Therefore, the primary aim of this systematic review is to provide information on the prevalence of the use of mobile technologies for smoking cessation among smokers and former smokers in high-income countries. A secondary aim is to examine the intention to use these technologies.</p></sec><sec id="s2" sec-type="methods"><title>Methods</title><sec id="s2-1"><title>Overall study design</title><p>This systematic review was conducted in accordance with the Joanna Briggs Institute guideline for systematic reviews of prevalence and incidence [<xref ref-type="bibr" rid="ref31">31</xref>]. The reporting follows the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) statement [<xref ref-type="bibr" rid="ref32">32</xref>], and its extension for searches (PRISMA-S; <xref ref-type="supplementary-material" rid="app2">Checklist 1</xref>). A study protocol was registered in advance in the PROSPERO (Prospective Register of Systematic Reviews; CRD42025647875).</p></sec><sec id="s2-2"><title>Literature Search</title><p>MEDLINE (via PubMed), Embase (via Elsevier), and PsycInfo (via EBSCO) were searched from inception to February 13, 2025. No restrictions were applied with regard to either language, study design, or publication date, and no search filters were used. The search strategy was developed by 1 researcher (ML) and reviewed by 2 other researchers (JH and FH). The final search strategies for all databases can be found in Table S1 in <xref ref-type="supplementary-material" rid="app1">Multimedia Appendix 1</xref>. To complement the database searches, a forward (citing) and backward (cited) citation analyses of the included studies were performed on May 5, 2025, using Web of Science Core Collection following the TARCiS statement [<xref ref-type="bibr" rid="ref33">33</xref>]. This analysis was repeated on newly included references until no additional studies could be identified, resulting in a second iteration on May 20, 2025, and a third iteration on May 22, 2025. Registries, online resources, and browsing were not searched, nor were other information sources (eg, contacting authors, experts, and manufacturers) used, as the focus of this review was exclusively on identifying published peer-reviewed studies.</p></sec><sec id="s2-3"><title>Eligibility Criteria</title><p>We included published observational studies, including cross-sectional studies and cohort studies with data analyzed in a cross-sectional manner. We excluded PhD theses and conference abstracts as well as interventional studies, including randomized controlled trials. Exceptions were made for reports of randomized controlled trials with a cross-sectional analysis of baseline data. No language restrictions were applied.</p><p>The study eligibility criteria were defined using the CoCoPop (condition, context, population) approach, which is recommended for reviews of prevalence and incidence data [<xref ref-type="bibr" rid="ref34">34</xref>].</p></sec><sec id="s2-4"><title>Condition</title><p>To be included, studies had to report the use of mobile technologies for smoking cessation, addressing smoking of any tobacco product. We included mobile technologies that function as stand-alone tools. The types of mobile technologies assessed in this review included mobile phone apps, SMS text messaging interventions, websites, web-based programs, and social media platforms accessed via mobile devices that provide informational or motivational content related to smoking cessation. Studies that referred to internet use as a smoking cessation resource, without specifying the access device, were included under the category of mobile technologies, acknowledging that a substantial proportion of internet use now occurs via mobile devices [<xref ref-type="bibr" rid="ref35">35</xref>].</p><p>Studies examining the use of interventions that relied exclusively on videoconferencing, telephone calls, or online forums and social media used solely for direct interaction between individuals were excluded.</p></sec><sec id="s2-5"><title>Context</title><p>For inclusion, the studies had to be conducted in high-income countries according to the OECD (Organisation for Economic Co-operation and Development)&#x2013;Development Assistance Committee to ensure greater transferability to the German context [<xref ref-type="bibr" rid="ref36">36</xref>].</p></sec><sec id="s2-6"><title>Population</title><p>Studies were required to include data on smokers and former smokers as defined by the study authors, with at least 100 individuals in these categories. Studies focusing on specific populations, such as patients with multiple sclerosis or students, were also considered if relevant. To minimize the risk of selection bias, studies exclusively involving individuals who had previously used a specific cessation technology were excluded.</p></sec><sec id="s2-7"><title>Study Selection</title><p>The search results were imported into EndNote (Version 20, Clarivate), where duplicates were removed. For screening, the results were transferred to Rayyan (Qatar Computing Research Institute). For calibration, all reviewers (ML, JH, and JO) independently screened 100 articles based on title and abstract for inclusion or exclusion. After consensus on these records, ML and one other reviewer (JH or JO) independently screened all remaining titles and abstracts. The full texts of all articles that met the inclusion criteria were also assessed independently by ML and one other reviewer (JH or JO). Any discrepancies were resolved by consensus or, if necessary, by consultation with the third reviewer.</p></sec><sec id="s2-8"><title>Data Extraction</title><p>The data were extracted directly into the results tables by ML and were subsequently verified by the second reviewer (JO). Discrepancies were resolved through discussion or by the third reviewer (JH). The following items were extracted: study characteristics, characteristics of the study population, definition of smokers, prevalences of mobile technology use for smoking cessation, age- and sex-stratified prevalences of mobile technology use for smoking cessation, types of mobile technology, and prevalences of the intention to use mobile technologies.</p></sec><sec id="s2-9"><title>Quality Assessment</title><p>The quality of the included studies was independently assessed by two reviewers (ML and JO) using the Joanna Briggs Institute&#x2019;s critical appraisal checklist for studies reporting prevalence data [<xref ref-type="bibr" rid="ref37">37</xref>], which was adapted for our research question (Table S2 in <xref ref-type="supplementary-material" rid="app1">Multimedia Appendix 1</xref>). The quality assessment was piloted to calibrate the reviewers using 2 studies. Any disagreement was resolved by discussion or by the third reviewer (JH).</p></sec><sec id="s2-10"><title>Data Synthesis</title><p>The data were summarized descriptively using a narrative synthesis. Due to substantial variability in the clinical and methodological characteristics of the studies, which would result in noncomparable outcomes and populations, it was deemed inappropriate to conduct a meta-analysis by pooling prevalence across studies [<xref ref-type="bibr" rid="ref37">37</xref>,<xref ref-type="bibr" rid="ref38">38</xref>]. Instead, this systematic review aimed to describe this variability and present prevalence estimates at the study level, as well as overall prevalence ranges categorized by prevalence type and mobile technologies. Subgroup analyses were conducted on the basis of sex and age, with the prevalence ranges being described in a descriptive manner.</p><p>For studies reporting multiple time points, only the most recent data were included to reflect the most current usage patterns. If multiple articles were based on the same study population, only the most recent publication was included. The quality assessment was carried out for each report.</p></sec><sec id="s2-11"><title>Deviation From the Protocol</title><p>During the peer-review process, it was recommended that studies assessing populations solely using noncombustible products, such as e-cigarettes or vapers, should not be included. In accordance with this recommendation, the primary focus of the review has now been narrowed to populations smoking tobacco products. However, given that the search and initial review also incorporated a systematic identification of studies focusing on the use of mobile technologies in the context of vaping cessation, we decided that these findings should also be presented briefly, but separated from studies on smoking cessation.</p></sec></sec><sec id="s3" sec-type="results"><title>Results</title><sec id="s3-1"><title>Study Selection</title><p>The database search identified 7110 records (<xref ref-type="fig" rid="figure1">Figure 1</xref>). After screening the title and abstract, 105 articles were read, and 21 articles reporting on 20 studies were included. A forward-backward citation search was performed on those articles, resulting in the inclusion of 8 additional articles. Based on those 8 articles, a second round of citation analysis was conducted, resulting in 3 additional reports for inclusion. The last round of citation analysis conducted with those 3 reports could not identify any new articles. Overall, 27 studies documented in 32 reports were included in this review. Of these, 25 focused on smoking cessation, while 2 studies focused on vaping cessation. All articles were written in English. The excluded articles are listed in Table S3 in <xref ref-type="supplementary-material" rid="app1">Multimedia Appendix 1</xref> with reasons for exclusion.</p><fig position="float" id="figure1"><label>Figure 1.</label><caption><p>PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) study selection diagram. Citation searching was conducted and reported following the TARCIS Statement. The assignment of the reasons for exclusion was done hierarchically in the order presented.</p></caption><graphic alt-version="no" mimetype="image" position="float" xlink:type="simple" xlink:href="jmir_v28i1e83072_fig01.png"/></fig></sec><sec id="s3-2"><title>Study and Participant Characteristics of the Studies on Smoking Cessation</title><p>The characteristics of the 25 studies focusing on smoking cessation are shown in <xref ref-type="table" rid="table1">Table 1</xref>. A total of 9 studies were conducted in the United States [<xref ref-type="bibr" rid="ref39">39</xref>-<xref ref-type="bibr" rid="ref47">47</xref>], 4 studies were from the United Kingdom [<xref ref-type="bibr" rid="ref30">30</xref>,<xref ref-type="bibr" rid="ref48">48</xref>-<xref ref-type="bibr" rid="ref50">50</xref>], 2 each from Norway [<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref52">52</xref>], Canada [<xref ref-type="bibr" rid="ref53">53</xref>,<xref ref-type="bibr" rid="ref54">54</xref>], and Australia [<xref ref-type="bibr" rid="ref55">55</xref>,<xref ref-type="bibr" rid="ref56">56</xref>], and 1 each from the Netherlands [<xref ref-type="bibr" rid="ref57">57</xref>] and from Greece [<xref ref-type="bibr" rid="ref58">58</xref>]. Four studies included several countries in their scope [<xref ref-type="bibr" rid="ref24">24</xref>-<xref ref-type="bibr" rid="ref26">26</xref>,<xref ref-type="bibr" rid="ref59">59</xref>]. All included studies used a cross-sectional design. In terms of data collection methods, 11 studies used online surveys, 4 relied on personal interviews, 4 applied mixed methods, 3 utilized paper-pencil surveys, 2 conducted telephone interviews, and 1 study did not report its data collection method. The types of mobile technologies investigated differed between studies and included websites or general internet use (n=16), smartphone apps (n=8), SMS text messaging programs (n=2), and social media (n=2). Six studies asked for the use of several tools without differentiation, which included web-based programs as well.</p><p>The number of participants per study ranged from 117 to 27,323. Although several studies reported the age distribution of their overall study population or subgroups, only 8 out of 25 provided the mean age specifically for smokers, with values ranging from 19.9 to 50.3 years. The proportion of female participants varied between 0% and 77% (n=18). Participants were categorized as either current or former smokers, with the definition of &#x201C;smoker&#x201D; varying between studies (Table S4 in <xref ref-type="supplementary-material" rid="app1">Multimedia Appendix 1</xref>). Over a third of the included studies (n=10) focused exclusively on smokers who had recently attempted to quit.</p><table-wrap id="t1" position="float"><label>Table 1.</label><caption><p>General characteristics of the included studies on smoking cessation (n=25) and vaping cessation (n=2).</p></caption><table id="table1" frame="hsides" rules="groups"><thead><tr><td align="left" valign="bottom">Authors and year</td><td align="left" valign="bottom">Country</td><td align="left" valign="bottom">Data collection</td><td align="left" valign="bottom">Year of data</td><td align="left" valign="bottom">Sample size, n</td><td align="left" valign="bottom">Population</td><td align="left" valign="bottom">Mean age (years); female sex (%)</td></tr></thead><tbody><tr><td align="left" valign="top" colspan="7">Smoking cessation</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Borrelli et al [<xref ref-type="bibr" rid="ref24">24</xref>] (2015)</td><td align="left" valign="top">United States/United Kingdom</td><td align="left" valign="top">Online survey</td><td align="char" char="." valign="top">2014</td><td align="left" valign="top">1000</td><td align="left" valign="top">Smokers aged 18 years and older</td><td align="left" valign="top">43.9 years; 55%</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Bottorff et al [<xref ref-type="bibr" rid="ref53">53</xref>] (2016)</td><td align="left" valign="top">Canada</td><td align="left" valign="top">Online survey</td><td align="char" char="." valign="top">2014</td><td align="left" valign="top">117</td><td align="left" valign="top">Smokers, only men<sup><xref ref-type="table-fn" rid="table1fn1">a</xref></sup> column</td><td align="left" valign="top">39.8 years; 0%</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Caraballo et al [<xref ref-type="bibr" rid="ref39">39</xref>] (2017)</td><td align="left" valign="top">United States</td><td align="left" valign="top">Online survey</td><td align="char" char="." valign="top">2014&#x2010;2016</td><td align="left" valign="top">15,943</td><td align="left" valign="top">Smokers aged 18 years and older who made a quit attempt in the last 3 months</td><td align="left" valign="top">N/R<sup><xref ref-type="table-fn" rid="table1fn2">b</xref></sup>; 48.7%</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Chevalking et al [<xref ref-type="bibr" rid="ref57">57</xref>] (2018)</td><td align="left" valign="top">Netherlands</td><td align="left" valign="top">Online survey</td><td align="char" char="." valign="top">2015&#x2010;2016</td><td align="left" valign="top">802</td><td align="left" valign="top">Smokers and former smokers<sup><xref ref-type="table-fn" rid="table1fn1">a</xref></sup></td><td align="left" valign="top">N/R</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Curry et al [<xref ref-type="bibr" rid="ref40">40</xref>] (2007) and companion report: Coups et al [<xref ref-type="bibr" rid="ref60">60</xref>] (2009)</td><td align="left" valign="top">United States</td><td align="left" valign="top">Personal interview</td><td align="char" char="." valign="top">2005</td><td align="left" valign="top">2747</td><td align="left" valign="top">Smokers aged 18 years and older who made a quit attempt in the past year</td><td align="left" valign="top">N/R</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Graham and Amato [<xref ref-type="bibr" rid="ref61">61</xref>] (2019)</td><td align="left" valign="top">United States</td><td align="left" valign="top">Online survey</td><td align="char" char="." valign="top">2017</td><td align="left" valign="top">1736</td><td align="left" valign="top">Smokers aged 18 years and older</td><td align="left" valign="top">N/R</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Gravely et al [<xref ref-type="bibr" rid="ref59">59</xref>] (2021)</td><td align="left" valign="top">Australia, Canada, England, and United States</td><td align="left" valign="top">Online survey</td><td align="char" char="." valign="top">2020</td><td align="left" valign="top">3614</td><td align="left" valign="top">Smokers, vapers, and former smokers aged 18 years and older who made a quit attempt or quit smoking in the last 2 years</td><td align="left" valign="top">N/R; 53%</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Hummel et al [<xref ref-type="bibr" rid="ref26">26</xref>] (2018)</td><td align="left" valign="top">England, Germany, Greece, Hungary, Netherlands, Poland, Romania, and Spain</td><td align="left" valign="top">Personal interview or online survey</td><td align="char" char="." valign="top">2016</td><td align="left" valign="top">10,683</td><td align="left" valign="top">Smokers aged 18 years and older who made a quit attempt in the past year</td><td align="left" valign="top">N/R</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Jackson et al [<xref ref-type="bibr" rid="ref30">30</xref>] (2019)</td><td align="left" valign="top">United Kingdom</td><td align="left" valign="top">Personal interview</td><td align="char" char="." valign="top">2006&#x2010;2018</td><td align="left" valign="top">18,929</td><td align="left" valign="top">Smokers aged 16 years and older who made at least 1 quit attempt in the past year</td><td align="left" valign="top">N/R; 52%</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Jackson et al [<xref ref-type="bibr" rid="ref48">48</xref>] (2022)</td><td align="left" valign="top">United Kingdom</td><td align="left" valign="top">Personal interview</td><td align="char" char="." valign="top">2020&#x2010;2021</td><td align="left" valign="top">1550</td><td align="left" valign="top">Smokers and former smokers (smoking during preceding year) aged 18 years and older who made at least 1 quit attempt in the past year</td><td align="left" valign="top">N/R; 50%</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Jackson et al [<xref ref-type="bibr" rid="ref49">49</xref>] (2025)</td><td align="left" valign="top">United Kingdom</td><td align="left" valign="top">Telephone interview</td><td align="char" char="." valign="top">2023&#x2010;2024</td><td align="left" valign="top">1642</td><td align="left" valign="top">Smokers and former smokers (smoking during preceding year) aged 16 years and older who made at least 1 quit attempt in the past year</td><td align="left" valign="top">N/R</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Jayakumar et al [<xref ref-type="bibr" rid="ref54">54</xref>] (2019)</td><td align="left" valign="top">Canada</td><td align="left" valign="top">Online survey</td><td align="char" char="." valign="top">2013&#x2010;2018</td><td align="left" valign="top">2773</td><td align="left" valign="top">Smokers and former smokers (had quit within last 3 years) aged 18 years and older</td><td align="left" valign="top">N/R; 64%</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Kostagiolas et al [<xref ref-type="bibr" rid="ref58">58</xref>] (2023)</td><td align="left" valign="top">Greece</td><td align="left" valign="top">Paper-pencil survey</td><td align="char" char="." valign="top">2019</td><td align="left" valign="top">150</td><td align="left" valign="top">Smokers aged 18 years and older</td><td align="left" valign="top">N/R; 58%</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Li et al [<xref ref-type="bibr" rid="ref56">56</xref>] (2025)</td><td align="left" valign="top">Australia</td><td align="left" valign="top">Online survey</td><td align="char" char="." valign="top">2017&#x2010;2020</td><td align="left" valign="top">1244</td><td align="left" valign="top">Smokers aged 18 years and older from rural/remote locations</td><td align="left" valign="top">43.6 years; 77%</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Lund and Lund [<xref ref-type="bibr" rid="ref52">52</xref>] (2022)</td><td align="left" valign="top">Norway</td><td align="left" valign="top">Telephone interview</td><td align="char" char="." valign="top">2017&#x2010;2020</td><td align="left" valign="top">874</td><td align="left" valign="top">Smokers and former smokers aged 20 years and older</td><td align="left" valign="top">50.3 years; 47%</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Lund and Lund [<xref ref-type="bibr" rid="ref51">51</xref>] (2023)</td><td align="left" valign="top">Norway</td><td align="left" valign="top">Online survey</td><td align="char" char="." valign="top">2020</td><td align="left" valign="top">1111</td><td align="left" valign="top">Smokers and former smokers<sup><xref ref-type="table-fn" rid="table1fn1">a</xref></sup> &#x2003;</td><td align="left" valign="top">N/R; 52.8%<sup><xref ref-type="table-fn" rid="table1fn3">c</xref></sup></td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Moon et al [<xref ref-type="bibr" rid="ref42">42</xref>] (2020)</td><td align="left" valign="top">United States</td><td align="left" valign="top">Paper-pencil survey</td><td align="char" char="." valign="top">2018&#x2010;2019</td><td align="left" valign="top">227</td><td align="left" valign="top">Smokers with Korean background<sup><xref ref-type="table-fn" rid="table1fn1">a</xref></sup></td><td align="left" valign="top">N/R; 12.8%</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Oliver et al [<xref ref-type="bibr" rid="ref43">43</xref>] (2018)</td><td align="left" valign="top">United States</td><td align="left" valign="top">Online survey or paper-pencil survey</td><td align="char" char="." valign="top">2013&#x2010;2017</td><td align="left" valign="top">180</td><td align="left" valign="top">Smokers aged 18-65 years</td><td align="left" valign="top">N/R</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Papadakis et al [<xref ref-type="bibr" rid="ref25">25</xref>] (2020)</td><td align="left" valign="top">England, Germany, Greece, Hungary, Netherlands, Poland, Romania, and Spain</td><td align="left" valign="top">N/R</td><td align="char" char="." valign="top">2017&#x2010;2018</td><td align="left" valign="top">2699</td><td align="left" valign="top">Smokers<sup><xref ref-type="table-fn" rid="table1fn1">a</xref></sup></td><td align="left" valign="top">N/R</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Patterson et al [<xref ref-type="bibr" rid="ref44">44</xref>] (2021)</td><td align="left" valign="top">United States</td><td align="left" valign="top">Personal interview and telephone interview</td><td align="char" char="." valign="top">2018&#x2010;2019</td><td align="left" valign="top">659</td><td align="left" valign="top">Smokers aged 18 years and older</td><td align="left" valign="top">N/R; 43%<sup><xref ref-type="table-fn" rid="table1fn4">d</xref></sup></td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Perski et al [<xref ref-type="bibr" rid="ref50">50</xref>] (2022) and companion reports: Beard et al [<xref ref-type="bibr" rid="ref62">62</xref>] (2016) and Perski et al [<xref ref-type="bibr" rid="ref63">63</xref>] (2019)</td><td align="left" valign="top">United Kingdom</td><td align="left" valign="top">Personal interview</td><td align="char" char="." valign="top">2014&#x2010;2020</td><td align="left" valign="top">5892</td><td align="left" valign="top">Smokers aged 16 years and older who made a quit attempt in the past year</td><td align="left" valign="top">N/R; 50%</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Ramo et al [<xref ref-type="bibr" rid="ref45">45</xref>] (2015)</td><td align="left" valign="top">United States</td><td align="left" valign="top">Online survey</td><td align="char" char="." valign="top">2010&#x2010;2011</td><td align="left" valign="top">570</td><td align="left" valign="top">Smokers aged 18-25 years</td><td align="left" valign="top">19.9 years; 30%</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Thrul et al [<xref ref-type="bibr" rid="ref46">46</xref>] (2021) and companion reports: Mojtabai et al [<xref ref-type="bibr" rid="ref64">64</xref>](2020) and Soulakova and Crockett [<xref ref-type="bibr" rid="ref65">65</xref>] (2018)</td><td align="left" valign="top">United States</td><td align="left" valign="top">Personal interview or telephone interview</td><td align="char" char="." valign="top">2010&#x2010;2011</td><td align="left" valign="top">27,323</td><td align="left" valign="top">Smokers aged 18 years and older</td><td align="left" valign="top">42.7 years; 46%</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Tofighi et al [<xref ref-type="bibr" rid="ref47">47</xref>](2019)</td><td align="left" valign="top">United States</td><td align="left" valign="top">Paper-pencil survey</td><td align="char" char="." valign="top">2015</td><td align="left" valign="top">157</td><td align="left" valign="top">Smokers enrolled as patients in inpatient detoxification treatment and post discharge (for alcohol and/or heroin)<sup><xref ref-type="table-fn" rid="table1fn1">a</xref></sup></td><td align="left" valign="top">43.7 years; 9%</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Twyman et al [<xref ref-type="bibr" rid="ref55">55</xref>] (2018)</td><td align="left" valign="top">Australia</td><td align="left" valign="top">Online survey</td><td align="char" char="." valign="top">2012&#x2010;2013</td><td align="left" valign="top">646</td><td align="left" valign="top">Smokers and former smokers aged 18 years and older who are financially disadvantaged and made a quit attempt before</td><td align="left" valign="top">39 years; 52%</td></tr><tr><td align="left" valign="top" colspan="7">Vaping cessation</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Dai et al [<xref ref-type="bibr" rid="ref66">66</xref>] (2023)</td><td align="left" valign="top">United States</td><td align="left" valign="top">Online survey</td><td align="char" char="." valign="top">2021</td><td align="left" valign="top">889</td><td align="left" valign="top">e-Cigarette<sup><xref ref-type="table-fn" rid="table1fn5">e</xref></sup> users, school grade 6&#x2010;12 years, who made quit attempts in the past year<sup><xref ref-type="table-fn" rid="table1fn1">a</xref></sup></td><td align="left" valign="top">N/R; 51%</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Jones et al [<xref ref-type="bibr" rid="ref67">67</xref>] (2023)</td><td align="left" valign="top">United States</td><td align="left" valign="top">Online survey</td><td align="left" valign="top">N/R</td><td align="left" valign="top">185</td><td align="left" valign="top">Vapers and former vapers aged 14-19 years</td><td align="left" valign="top">16.9 years; 52%</td></tr></tbody></table><table-wrap-foot><fn id="table1fn1"><p><sup>a</sup>Included age not displayed.</p></fn><fn id="table1fn2"><p><sup>b</sup>N/R: not reported.</p></fn><fn id="table1fn3"><p><sup>c</sup>Own calculation based on the numbers provided by the authors in Table 2 (587/1111&#x00D7;100=52.8%).</p></fn><fn id="table1fn4"><p><sup>d</sup>Own calculation based on the numbers provided by the authors in Table 2 (280/659&#x00D7;100=42.5%).</p></fn><fn id="table1fn5"><p><sup>e</sup>e-Cigarette: electronic cigarette.</p></fn></table-wrap-foot></table-wrap></sec><sec id="s3-3"><title>Prevalence of Use of Mobile Technologies for Smoking Cessation</title><p>The data collection periods from the 25 studies on smoking cessation span from 2005 to 2024. A noticeable clustering of studies was observed between 2014 and 2020 (<xref ref-type="fig" rid="figure2">Figure 2</xref>), most of which focused on the use of apps and internet-based interventions. After 2021, fewer studies reporting on the use of mobile technologies for smoking cessation were identified.</p><p>A total of 8 studies reported the lifetime prevalence of using mobile technology for smoking cessation, which ranged from 2.5% to 35.9% (see <xref ref-type="table" rid="table2">Table 2</xref>). Four of these studies examined the usage of websites or the internet for smoking cessation, with prevalences ranging from 7.1% up to 35.9%. Mobile app usage ranged from 2.5% to 15.2% (n=4). SMS text messaging programs showed lifetime prevalences between 2.7% and 13.2% (n=2). Two studies presented data on social media use. While 1 study reported a combined prevalence of 22% for social media, another study differentiated between Twitter and Facebook and reported prevalences between 7.6% and 14.8%.</p><p>Period prevalence, covering usage within the past several months to the last 2 years, was assessed in 4 studies and ranged from 0% to 12%. Three studies examining the use of websites or the internet for smoking cessation were identified, with 1 study reporting a prevalence of 12%, while the other 2 observed prevalences of less than 2%. One study presented a combined prevalence for apps or SMS text messaging, showing that these tools were never used.</p><p>Point prevalence, referring to use during the most recent quit attempt, was reported in 11 studies, with prevalence ranging from 1.1% to 10.9%. For websites and internet use, the prevalences of use ranged from 0% to 10.9% (n=8). Four studies examined smartphone app use, which ranged between 0% and 10.7%.</p><p>Two studies reported more than 1 type of prevalence, and 1 study did not specify the type of prevalence assessed.</p><fig position="float" id="figure2"><label>Figure 2.</label><caption><p>Use of mobile technologies for smoking cessation among smokers and former smokers over time, by prevalence type and technology (n=23; Curry et al [<xref ref-type="bibr" rid="ref40">40</xref>] and Ramo et al [<xref ref-type="bibr" rid="ref45">45</xref>] were not included in the figure as no prevalence type was stated or only stratified results were presented).</p></caption><graphic alt-version="no" mimetype="image" position="float" xlink:type="simple" xlink:href="jmir_v28i1e83072_fig02.png"/></fig><table-wrap id="t2" position="float"><label>Table 2.</label><caption><p>Prevalence of the use of different mobile technology tools for smoking cessation among smokers and former smokers, categorized by lifetime, period, and point prevalence.</p></caption><table id="table2" frame="hsides" rules="groups"><thead><tr><td align="left" valign="bottom">Authors and year</td><td align="left" valign="bottom">Country (Sample size, n)</td><td align="left" valign="bottom">Year of data</td><td align="left" valign="bottom">Type and prevalence of mobile technology use for smoking cessation, %</td></tr></thead><tbody><tr><td align="left" valign="top" colspan="4">Lifetime prevalences</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Borrelli et al [<xref ref-type="bibr" rid="ref24">24</xref>] (2015)</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>United States (n=500)</p></list-item><list-item><p>United Kingdom (n=500)</p></list-item></list></td><td align="left" valign="top">2014</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>United States</p><list list-type="bullet"><list-item><p>Websites: 26.2%</p></list-item><list-item><p>Text messaging program: 13.2%</p></list-item><list-item><p>Apps: 15.2%</p></list-item><list-item><p>Twitter: 12.2%</p></list-item><list-item><p>Facebook: 14.8%</p></list-item></list></list-item><list-item><p>United Kingdom</p><list list-type="bullet"><list-item><p>Website: 25.6%</p></list-item><list-item><p>Text messaging program: 8.8%</p></list-item><list-item><p>Apps: 12.8%</p></list-item><list-item><p>Twitter: 7.6%</p></list-item><list-item><p>Facebook: 10.4%</p></list-item></list></list-item></list></td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Chevalking et al [<xref ref-type="bibr" rid="ref57">57</xref>] (2018)</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>Netherlands (n=802)</p></list-item></list></td><td align="left" valign="top">2015&#x2010;2016</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>Web-based program or apps: 15.5%<sup><xref ref-type="table-fn" rid="table2fn1">a</xref></sup></p></list-item><list-item><p>Websites: 7.1%<sup><xref ref-type="table-fn" rid="table2fn2">b</xref></sup></p></list-item></list></td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Graham and Amato [<xref ref-type="bibr" rid="ref61">61</xref>] (2019)</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>United States (n=1736)</p></list-item></list></td><td align="left" valign="top">2017</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>Websites: 35.9%<sup><xref ref-type="table-fn" rid="table2fn3">c</xref></sup></p></list-item></list></td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Jayakumar et al [<xref ref-type="bibr" rid="ref54">54</xref>] (2020)</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>Canada (n=2773)</p></list-item></list></td><td align="left" valign="top">2013&#x2010;2018</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>Apps: 2.5%</p></list-item></list></td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Kostagiolas et al [<xref ref-type="bibr" rid="ref58">58</xref>] (2023)</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>Greece (n=150)</p></list-item></list></td><td align="left" valign="top">2019</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>Internet search engines: 33.3%<sup><xref ref-type="table-fn" rid="table2fn4">d</xref></sup></p></list-item><list-item><p>Social media (Facebook, Twitter, Blogs): 22.0%<sup><xref ref-type="table-fn" rid="table2fn5">e</xref></sup></p></list-item><list-item><p>Public institutions websites: 18.7%<sup><xref ref-type="table-fn" rid="table2fn6">f</xref></sup></p></list-item><list-item><p>Medical websites: 23.3%<sup><xref ref-type="table-fn" rid="table2fn7">g</xref></sup></p></list-item></list></td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Li et al [<xref ref-type="bibr" rid="ref56">56</xref>] (2025)</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>Australia (n=1244)</p></list-item></list></td><td align="left" valign="top">2017&#x2010;2020</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>Online services: 13.5%</p></list-item><list-item><p>Text messaging program: 2.7%</p></list-item></list></td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Moon et al [<xref ref-type="bibr" rid="ref42">42</xref>] (2020)</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>United States (n=227)</p></list-item></list></td><td align="left" valign="top">2018&#x2010;2019</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>Apps: 3.5%</p></list-item></list></td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Oliver et al [<xref ref-type="bibr" rid="ref43">43</xref>] (2018)</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>United States (n=180)</p></list-item></list></td><td align="left" valign="top">2013&#x2010;2017</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>Apps: 6.1%</p></list-item></list></td></tr><tr><td align="left" valign="top" colspan="4">Period prevalences</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Bottorff et al [<xref ref-type="bibr" rid="ref53">53</xref>] (2016) (Period prevalence: last 3 months)</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>Canada (n=117)</p></list-item></list></td><td align="left" valign="top">2014</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>Websites: 12%</p></list-item></list></td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Patterson et al [<xref ref-type="bibr" rid="ref44">44</xref>] (2021) (Period prevalence: last 2 years)</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>United States (n=659)</p></list-item></list></td><td align="left" valign="top">2018&#x2010;2019</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>Internet/web-based program: 1.7%<sup><xref ref-type="table-fn" rid="table2fn8">h</xref></sup></p></list-item><list-item><p>Videos: 0.8%<sup><xref ref-type="table-fn" rid="table2fn9">i</xref></sup></p></list-item></list></td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Thrul et al [<xref ref-type="bibr" rid="ref46">46</xref>] (2021) (Period prevalence: past year)</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>United States (n=27,323)</p></list-item></list></td><td align="left" valign="top">2010&#x2010;2011</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>Internet/websites/web-based programs: 0.8%<sup><xref ref-type="table-fn" rid="table2fn3">c</xref></sup></p></list-item></list></td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Tofighi et al [<xref ref-type="bibr" rid="ref47">47</xref>] (2019) (Period prevalence: past year)</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>United States (n=157)</p></list-item></list></td><td align="left" valign="top">2015</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>Apps or text messaging tool: 0%</p></list-item></list></td></tr><tr><td align="left" valign="top" colspan="4">Point prevalences (for last quit attempt)</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Caraballo et al [<xref ref-type="bibr" rid="ref39">39</xref>] (2017)</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>United States (n=15,943)</p></list-item></list></td><td align="left" valign="top">2014&#x2010;2016</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>Websites: 7.1%<sup><xref ref-type="table-fn" rid="table2fn3">c</xref></sup></p></list-item></list></td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Curry et al [<xref ref-type="bibr" rid="ref40">40</xref>] (2007)</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>United States (n=2747)</p></list-item></list></td><td align="left" valign="top">2005</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>Internet: N/R<sup><xref ref-type="table-fn" rid="table2fn10">j</xref></sup></p></list-item></list></td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Gravely et al [<xref ref-type="bibr" rid="ref59">59</xref>] (2021)</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>Australia, Canada, England, United States (n=3614)</p></list-item></list></td><td align="left" valign="top">2020</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>Apps: 4.6%<sup><xref ref-type="table-fn" rid="table2fn3">c</xref></sup></p></list-item><list-item><p>Websites: 8.5%<sup><xref ref-type="table-fn" rid="table2fn3">c</xref></sup></p></list-item></list></td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Hummel et al [<xref ref-type="bibr" rid="ref26">26</xref>] (2018)</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>England (n=3536)</p></list-item><list-item><p>Germany (n=1003)</p></list-item><list-item><p>Greece (n=1000)</p></list-item><list-item><p>Hungary (n=1000)</p></list-item><list-item><p>Netherlands (n=1136)</p></list-item><list-item><p>Poland (n=1006)</p></list-item><list-item><p>Romania (n=1001)</p></list-item><list-item><p>Spain (n=1001)</p></list-item></list></td><td align="left" valign="top">2016</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>Internet</p><list list-type="bullet"><list-item><p>England: 10.9%<sup><xref ref-type="table-fn" rid="table2fn3">c</xref></sup></p></list-item><list-item><p>Germany: 4.8%<sup><xref ref-type="table-fn" rid="table2fn3">c</xref></sup></p></list-item><list-item><p>Greece: 0.4%<sup><xref ref-type="table-fn" rid="table2fn3">c</xref></sup></p></list-item><list-item><p>Hungary: 2.7%<sup><xref ref-type="table-fn" rid="table2fn3">c</xref></sup></p></list-item><list-item><p>Netherlands: 5.7%<sup><xref ref-type="table-fn" rid="table2fn3">c</xref></sup> (period prevalence: last 6 months)</p></list-item><list-item><p>Poland: 5.7%<sup><xref ref-type="table-fn" rid="table2fn3">c</xref></sup></p></list-item><list-item><p>Romania: 3.2%<sup><xref ref-type="table-fn" rid="table2fn3">c</xref></sup></p></list-item><list-item><p>Spain: 0%<sup><xref ref-type="table-fn" rid="table2fn3">c</xref></sup></p></list-item></list></list-item></list></td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Jackson et al [<xref ref-type="bibr" rid="ref30">30</xref>] (2019)</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>United Kingdom (n=18,929)</p></list-item></list></td><td align="left" valign="top">2006&#x2010;2018</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>Websites: 1.1%</p></list-item></list></td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Jackson et al [<xref ref-type="bibr" rid="ref48">48</xref>] (2022)</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>United Kingdom (n=1550)</p></list-item></list></td><td align="left" valign="top">2020&#x2010;2021</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>Websites: 4.1%</p></list-item></list></td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Jackson et al [<xref ref-type="bibr" rid="ref49">49</xref>] (2025)</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>United Kingdom (n=1642)</p></list-item></list></td><td align="left" valign="top">2023&#x2010;2024</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>Websites: 4.6%<sup><xref ref-type="table-fn" rid="table2fn3">c</xref></sup></p></list-item><list-item><p>Apps: 3.6%<sup><xref ref-type="table-fn" rid="table2fn3">c</xref></sup></p></list-item></list></td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Lund and Lund [<xref ref-type="bibr" rid="ref52">52</xref>] (2022)</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>Norway (n=874)</p></list-item></list></td><td align="left" valign="top">2017&#x2010;2020</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>Web/mobile: 9.2%</p></list-item></list></td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Lund and Lund [<xref ref-type="bibr" rid="ref51">51</xref>] (2023)</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>Norway (n=1111)</p></list-item></list></td><td align="left" valign="top">2020</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>Apps: 10.7%</p></list-item></list></td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Papadakis et al [<xref ref-type="bibr" rid="ref25">25</xref>] (2020)</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>England (n=1482)</p></list-item><list-item><p>Germany (n=185)</p></list-item><list-item><p>Greece (n=157)</p></list-item><list-item><p>Hungary (n=127)</p></list-item><list-item><p>Poland (n=179)</p></list-item><list-item><p>Romania (n=284)</p></list-item><list-item><p>Spain (n=285)</p></list-item></list></td><td align="left" valign="top">2017&#x2010;2018</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>Apps/Internet:</p><list list-type="bullet"><list-item><p>England: 6.2%<sup><xref ref-type="table-fn" rid="table2fn3">c</xref></sup>/10.2<sup><xref ref-type="table-fn" rid="table2fn3">c</xref></sup></p></list-item><list-item><p>Germany: 4.2%<sup><xref ref-type="table-fn" rid="table2fn3">c</xref></sup>/6.7<sup><xref ref-type="table-fn" rid="table2fn3">c</xref></sup></p></list-item><list-item><p>Greece: 0.0%<sup><xref ref-type="table-fn" rid="table2fn3">c</xref></sup>/0.7<sup><xref ref-type="table-fn" rid="table2fn3">c</xref></sup></p></list-item><list-item><p>Hungary: 1.3%<sup><xref ref-type="table-fn" rid="table2fn3">c</xref></sup>/ 2.6<sup><xref ref-type="table-fn" rid="table2fn3">c</xref></sup></p></list-item><list-item><p>Poland: 0.8%<sup><xref ref-type="table-fn" rid="table2fn3">c</xref></sup>/1.8<sup><xref ref-type="table-fn" rid="table2fn3">c</xref></sup></p></list-item><list-item><p>Romania: 0.4%<sup><xref ref-type="table-fn" rid="table2fn3">c</xref></sup>/1.7<sup><xref ref-type="table-fn" rid="table2fn3">c</xref></sup></p></list-item><list-item><p>Spain: 0.9%<sup><xref ref-type="table-fn" rid="table2fn3">c</xref></sup>/0.3<sup><xref ref-type="table-fn" rid="table2fn3">c</xref></sup></p></list-item></list></list-item></list></td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Perski et al [<xref ref-type="bibr" rid="ref50">50</xref>] (2022)</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>United Kingdom (n=5892)</p></list-item></list></td><td align="left" valign="top">2014&#x2010;2020</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>Digital aid (websites, smartphone apps, and other): 2.5%</p></list-item></list></td></tr><tr><td align="left" valign="top" colspan="4">Prevalence type not reported or more than one prevalence type</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Ramo et al [<xref ref-type="bibr" rid="ref45">45</xref>] (2015) (Prevalence type not reported)</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>USA (n=570)</p></list-item></list></td><td align="left" valign="top">2010&#x2010;2011</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>Internet: 2%</p></list-item></list></td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Twyman et al [<xref ref-type="bibr" rid="ref55">55</xref>] (2018) (Life-time prevalence in current smokers, point prevalence in former smokers)</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>Australia (n=646)</p></list-item></list></td><td align="left" valign="top">2012&#x2010;2013</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>Internet: 1%</p></list-item></list></td></tr></tbody></table><table-wrap-foot><fn id="table2fn1"><p><sup>a</sup>Own calculation based on the numbers provided by Chevalking et al [<xref ref-type="bibr" rid="ref57">57</xref>] on page 4 (124/802 &#x00D7; 100 = 15.5%).</p></fn><fn id="table2fn2"><p><sup>b</sup>Own calculation based on the numbers provided by Chevalking et al [<xref ref-type="bibr" rid="ref57">57</xref>] on page 4 (57/802 &#x00D7; 100 = 7.1%).</p></fn><fn id="table2fn3"><p><sup>c</sup>Weighted results.</p></fn><fn id="table2fn4"><p><sup>d</sup>Own calculation based on the numbers provided by Kostagiolas et al [<xref ref-type="bibr" rid="ref58">58</xref>] in Multimedia Appendix 1 [(26 + 24)/150 &#x00D7; 100 = 33.3%].</p></fn><fn id="table2fn5"><p><sup>e</sup>Own calculation based on the numbers provided by Kostagiolas et al [<xref ref-type="bibr" rid="ref58">58</xref>] in Multimedia Appendix 1 [(20 +13)/150 &#x00D7;100 = 22.0%].</p></fn><fn id="table2fn6"><p><sup>f</sup>Own calculation based on the numbers provided by Kostagiolas et al [<xref ref-type="bibr" rid="ref58">58</xref>] in Multimedia Appendix 1 [(13 + 15)/150 &#x00D7; 100 = 18.7%].</p></fn><fn id="table2fn7"><p><sup>g</sup>Own calculation based on the numbers provided by Kostagiolas et al [<xref ref-type="bibr" rid="ref58">58</xref>] in Multimedia Appendix 1 [(15 + 20)/150 &#x00D7; 100 = 23.3%].</p></fn><fn id="table2fn8"><p><sup>h</sup>Own calculation based on the numbers provided by Patterson et al [<xref ref-type="bibr" rid="ref44">44</xref>] in Table 2 [(3 + 8)/659 &#x00D7; 100 = 1.7%].</p></fn><fn id="table2fn9"><p><sup>i</sup>Own calculation based on the numbers provided by Patterson et al [<xref ref-type="bibr" rid="ref44">44</xref>] in Table 2 [(1 + 4)/659 &#x00D7; 100 = 0.8%].</p></fn><fn id="table2fn10"><p><sup>j</sup>N/R: not reported.</p></fn></table-wrap-foot></table-wrap></sec><sec id="s3-4"><title>Prevalence of Use of Mobile Technologies for Smoking Cessation, Stratified by Sex and Age</title><p>A total of 7 studies reported sex-stratified prevalences of mobile technology use for smoking cessation (Table S5 in <xref ref-type="supplementary-material" rid="app1">Multimedia Appendix 1</xref>). Of these, 1 study focused on lifetime prevalences, 2 on period prevalences, and 5 on point prevalences. The study on lifetime prevalence and both studies on period prevalences found comparable usage patterns between males and females. Of the 5 studies that reported point prevalences, 3 did not demonstrate any sex-specific differences in utilization. One study presented higher prevalences of app utilization in females, and 1 study identified significant sex differences in internet utilization that varied across different countries. While males reported higher internet use for smoking cessation in Germany (6.6% males vs 2.9% females), England (14.4% vs 7.3%), Hungary (5.3% vs 0%), and Poland (7.7% vs 3.3%), the opposite was observed in the Netherlands (5.3% vs 6.3%) and Norway (for app use; 5.9% vs 15%), where females reported higher usage.</p><p>A total of 5 studies (1 on period prevalence and 4 on point prevalences) reported age-stratified data. Four of the studies assessed the utilization of websites or the internet, and one study assessed the utilization of mobile apps. Regardless of the prevalence type and mobile technology, younger individuals have been found to demonstrate higher utilization of mobile technologies.</p></sec><sec id="s3-5"><title>Intention to Use Mobile Technology for Smoking Cessation</title><p>Two studies examined the intention to use mobile technologies for smoking cessation (<xref ref-type="table" rid="table3">Table 3</xref>). One of these studies reported a high intention to use websites (46.7%) and smartphone apps (42.7%). The intention to use SMS text messaging programs was found to be 28.5%, whereas the use of social media, including Twitter and Facebook, was found to be 18.95% and 28.1%, respectively. The other study concentrated on social media in general, reporting an intention to use of 31%.</p><table-wrap id="t3" position="float"><label>Table 3.</label><caption><p>The prevalence of smokers&#x2019; intentions to use mobile technologies to help them quit smoking in the future.</p></caption><table id="table3" frame="hsides" rules="groups"><thead><tr><td align="left" valign="bottom">Authors and year</td><td align="left" valign="bottom">Country (Sample size, n)</td><td align="left" valign="bottom">Outcome</td><td align="left" valign="bottom">Prevalence of intention to use mobile technologies in the future, %</td></tr></thead><tbody><tr><td align="left" valign="top">Borrelli et al [<xref ref-type="bibr" rid="ref24">24</xref>] (2015)</td><td align="left" valign="top">United States and United Kingdom (n=1000)</td><td align="left" valign="top">Future intentions to use technology to quit smoking</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>Websites: 46.7%</p></list-item><list-item><p>SMS text messaging program: 28.5%<sup><xref ref-type="table-fn" rid="table3fn1">a</xref></sup></p></list-item><list-item><p>Smartphone app: 42.7%</p></list-item><list-item><p>Twitter: 19.5%<sup><xref ref-type="table-fn" rid="table3fn2">b</xref></sup></p></list-item><list-item><p>Facebook: 28.1%<sup><xref ref-type="table-fn" rid="table3fn3">c</xref></sup></p></list-item></list></td></tr><tr><td align="left" valign="top">Ramo et al [<xref ref-type="bibr" rid="ref45">45</xref>] (2015)</td><td align="left" valign="top">United States (n=570)</td><td align="left" valign="top">Intention to use strategies to cut down/quit smoking</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>Social media: 31%</p></list-item></list></td></tr></tbody></table><table-wrap-foot><fn id="table3fn1"><p><sup>a</sup>Own calculation based on the numbers provided by the authors in Table 5 [(157+128)/1000=28.5%].</p></fn><fn id="table3fn2"><p><sup>b</sup>Own calculation based on the numbers provided by the authors in Table 5 [(113+82)/1000=19.5%].</p></fn><fn id="table3fn3"><p><sup>c</sup>Own calculation based on the numbers provided by the authors in Table 5 [(152+129)/1000=28.1%].</p></fn></table-wrap-foot></table-wrap></sec><sec id="s3-6"><title>Prevalence of Use and Intention to Use Mobile Technologies for Vaping Cessation</title><p>A total of 2 studies were identified that focus on vaping cessation [<xref ref-type="bibr" rid="ref66">66</xref>,<xref ref-type="bibr" rid="ref67">67</xref>]. The characteristics of these studies are presented in <xref ref-type="table" rid="table2">Table 2</xref>. Both studies were conducted in the United States, employed a cross-sectional design, and used an online survey for data collection. One study presented lifetime prevalences of the use of SMS text messaging programs (17.3%), apps (12.4%), web-based programs (9.7%), and different social media platforms (1.1% to 12.4%; Table S6 in <xref ref-type="supplementary-material" rid="app1">Multimedia Appendix 1</xref>). The other study presented period prevalences of the use of the internet (6.3%) and apps or SMS text messaging programs (5.5%). The intention to use mobile technologies for vaping cessation was presented in 1 study (Table S6 in <xref ref-type="supplementary-material" rid="app1">Multimedia Appendix 1</xref>), with the highest intention to use mobile apps (34.6%) being followed by SMS text messaging programs (30.8%) and social media (22.8%).</p></sec><sec id="s3-7"><title>Quality Assessment of Studies on Smoking Cessation</title><p>Of the 25 studies on smoking cessation, approximately half employed an appropriate sampling frame to address the target population (n=1; <xref ref-type="table" rid="table4">Table 4</xref>) and used appropriate sampling methods (n=13). A suitable sample size was reported in 80% (20/25) of the studies, while 40% (10/25) provided sufficient detail on study methodology. Forty percent (10/25) of the studies demonstrated unclear attrition, while 56% (14/25) reported sufficient sample coverage. All studies relied on self-reported data. The outcome was measured in a standard and reliable manner in 88% (22/25) of the studies, and 80% (20/25) of the studies applied appropriate statistical analyses. Furthermore, 72% (18/25) of the studies did not report the response rate, and 1 study exhibited an inadequate response rate.</p><p>The quality of studies varies according to the prevalence types. While only 13% (1/8) of studies reporting lifetime prevalences employed an appropriate sample frame, 25% (1/4) of studies reporting period prevalences and 81% (9/11) of those on point prevalences did so. Furthermore, appropriate sampling methods were employed in 13% (1/8) of studies reporting lifetime prevalences compared to 50% (2/4) of studies reporting period prevalences and 81% (9/11) of studies reporting point prevalences. The sample size was deemed to be adequate in 63% (5/8) of studies reporting lifetime prevalences, 50% (2/4) of studies reporting period prevalences, and 100% (11/11) of studies reporting point prevalences. With regard to the reporting of study methodology, 9% (1/11) of studies on point prevalences were less adequately reported than 50% (4/8) of studies on lifetime prevalences and 75% (3/4) of studies on period prevalences. For all other categories, there is only minor variability in study quality.</p><table-wrap id="t4" position="float"><label>Table 4.</label><caption><p>Overview of the quality of the included studies<sup><xref ref-type="table-fn" rid="table4fn1">a</xref></sup>.</p></caption><table id="table4" frame="hsides" rules="groups"><thead><tr><td align="left" valign="bottom"/><td align="left" valign="bottom">Was the sample frame appropriate to address the target population?</td><td align="left" valign="bottom">Were study participants sampled in an appropriate way?</td><td align="left" valign="bottom">Was the sample size adequate?</td><td align="left" valign="bottom">Were the study subjects and the setting described in detail?</td><td align="left" valign="bottom">Was the data analysis conducted with sufficient coverage of the identified sample?</td><td align="left" valign="bottom">Were valid methods used for the identification of the condition?</td><td align="left" valign="bottom">Was the condition measured in a standard, reliable way for all participants?</td><td align="left" valign="bottom">Was there appropriate statistical analysis?</td><td align="left" valign="bottom">Was the response rate adequate, and if not, was the low response rate managed appropriately?</td></tr></thead><tbody><tr><td align="left" valign="top" colspan="10">Smoking cessation</td></tr><tr><td align="left" valign="top" colspan="10"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Lifetime prevalence</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Borrelli et al [<xref ref-type="bibr" rid="ref24">24</xref>] (2015)</td><td align="left" valign="top">No</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">No</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Unclear</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Chevalking et al [<xref ref-type="bibr" rid="ref57">57</xref>] (2018)</td><td align="left" valign="top">No</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Unclear</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Unclear</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Graham and Amato [<xref ref-type="bibr" rid="ref61">61</xref>] (2019)</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Unclear</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Jayakumar et al [<xref ref-type="bibr" rid="ref54">54</xref>] (2019)</td><td align="left" valign="top">No</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">No</td><td align="left" valign="top">Unclear</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Unclear</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Kostagiolas et al [<xref ref-type="bibr" rid="ref58">58</xref>] (2023)</td><td align="left" valign="top">Unclear</td><td align="left" valign="top">Unclear</td><td align="left" valign="top">No</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Li et al [<xref ref-type="bibr" rid="ref56">56</xref>] (2025)</td><td align="left" valign="top">No</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Unclear</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Unclear</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Moon et al [<xref ref-type="bibr" rid="ref42">42</xref>] (2020)</td><td align="left" valign="top">No</td><td align="left" valign="top">No</td><td align="left" valign="top">No</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Unclear</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Oliver et al [<xref ref-type="bibr" rid="ref43">43</xref>] (2018)</td><td align="left" valign="top">No</td><td align="left" valign="top">No</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">No</td><td align="left" valign="top">No</td><td align="left" valign="top">No</td><td align="left" valign="top">Unclear</td></tr><tr><td align="left" valign="top" colspan="10"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Period prevalence</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Bottorff et al [<xref ref-type="bibr" rid="ref53">53</xref>] (2016)</td><td align="left" valign="top">No</td><td align="left" valign="top">No</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Unclear</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Unclear</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Patterson et al [<xref ref-type="bibr" rid="ref44">44</xref>] (2021)</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">No</td><td align="left" valign="top">Unclear</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Unclear</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Thrul et al [<xref ref-type="bibr" rid="ref46">46</xref>] (2021)</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">No</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Unclear</td></tr><tr><td align="left" valign="top">&#x2003;&#x2003;Mojtabai et al [<xref ref-type="bibr" rid="ref64">64</xref>] (2020)</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">No</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Unclear</td></tr><tr><td align="left" valign="top">&#x2003;Soulakova and Crockett [<xref ref-type="bibr" rid="ref65">65</xref>] (2016)</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">No</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Unclear</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Tofighi et al [<xref ref-type="bibr" rid="ref47">47</xref>] (2019)</td><td align="left" valign="top">No</td><td align="left" valign="top">No</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Unclear</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Unclear</td></tr><tr><td align="left" valign="top" colspan="10"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Point prevalence</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Caraballo et al [<xref ref-type="bibr" rid="ref39">39</xref>] (2017)</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">No</td><td align="left" valign="top">Unclear</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Curry et al [<xref ref-type="bibr" rid="ref40">40</xref>] (2007)</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Coups et al [<xref ref-type="bibr" rid="ref60">60</xref>] (2009)</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Gravely et al [<xref ref-type="bibr" rid="ref59">59</xref>] (2021)</td><td align="left" valign="top">No</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Unclear</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Hummel et al [<xref ref-type="bibr" rid="ref26">26</xref>] (2018)</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">No</td><td align="left" valign="top">Unclear</td><td align="left" valign="top">No</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Jackson et al [<xref ref-type="bibr" rid="ref30">30</xref>] (2019)</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Unclear</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Jackson et al [<xref ref-type="bibr" rid="ref48">48</xref>] (2022)</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Unclear</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Jackson et al [<xref ref-type="bibr" rid="ref49">49</xref>] (2025)</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Unclear</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Lund and Lund [<xref ref-type="bibr" rid="ref52">52</xref>] (2022)</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">No</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Lund and Lund [<xref ref-type="bibr" rid="ref51">51</xref>] (2023)<break/></td><td align="left" valign="top">No</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">No</td><td align="left" valign="top">Unclear</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">No</td><td align="left" valign="top">Unclear</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Papadakis et al [<xref ref-type="bibr" rid="ref25">25</xref>] (2020)</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">No</td><td align="left" valign="top">Unclear</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Perski et al [<xref ref-type="bibr" rid="ref50">50</xref>] (2022)</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Unclear</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Beard et al [<xref ref-type="bibr" rid="ref62">62</xref>] (2016)</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Unclear</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Perski et al [<xref ref-type="bibr" rid="ref63">63</xref>] (2019)</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Unclear</td></tr><tr><td align="left" valign="top" colspan="10"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Prevalence type not reported or more than one prevalence type</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Ramo et al [<xref ref-type="bibr" rid="ref45">45</xref>] (2015)</td><td align="left" valign="top">No</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">No</td><td align="left" valign="top">Unclear</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Twyman et al [<xref ref-type="bibr" rid="ref55">55</xref>] (2018)</td><td align="left" valign="top">No</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td></tr><tr><td align="left" valign="top" colspan="10">Vaping cessation</td></tr><tr><td align="left" valign="top" colspan="10"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Lifetime prevalence</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Dai et al [<xref ref-type="bibr" rid="ref66">66</xref>] (2023)</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td></tr><tr><td align="left" valign="top" colspan="10"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Period prevalence</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Jones et al [<xref ref-type="bibr" rid="ref67">67</xref>] (2023)</td><td align="left" valign="top">No</td><td align="left" valign="top">No</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">No</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Yes</td><td align="left" valign="top">Unclear</td></tr></tbody></table><table-wrap-foot><fn id="table4fn1"><p><sup>a</sup>Further information on the quality assessment criteria can be found in Table S2 in <xref ref-type="supplementary-material" rid="app1">Multimedia Appendix 1</xref>.</p></fn></table-wrap-foot></table-wrap></sec><sec id="s3-8"><title>Quality Assessment of Studies on Vaping Cessation</title><p>Of the 2 studies on vaping cessation, 1 study reporting lifetime prevalences employed an appropriate sampling frame as well as appropriate sampling methods and a suitable sample size, whereas the study reporting period prevalences did not. The study methodology was only described in sufficient detail by the study on period prevalence. Both studies had sufficient sample coverage, measured the outcomes in a standard and reliable manner, and employed appropriate statistical analyses but relied on self-reported data.</p></sec></sec><sec id="s4" sec-type="discussion"><title>Discussion</title><sec id="s4-1"><title>Principal Findings</title><p>This systematic review identified 25 studies examining smoking and 2 studies focusing on vaping cessation. Studies on smoking cessation have revealed a wide variability in the reported prevalences of mobile technology use for smoking cessation, ranging from 0% to 35.9% within the data collection period spanning from 2005 to 2024. The clinical and methodological variability observed was influenced by the type of prevalence measured, the specific mobile technology examined, the year of data collection, and the population under study. The lifetime prevalences of mobile technology use for smoking cessation (2.5%&#x2010;35.9 %; n=8) were found to be higher than the period prevalences (0%&#x2010;12%; n=4) and point prevalences (1.1%&#x2010;10.9%; n=11). Regardless of the prevalence type, the internet was the most frequently used technology (0.8%&#x2010;35.9%; n=14). In some countries, sex differences were observed, with males usually showing higher prevalences than females. In addition, younger people consistently showed a higher usage of mobile tools. The intention to use was much higher than the actual usage, with prevalences up to 46.7% for websites. In the 2 studies on vaping cessation, the prevalence ranged from 1.1% to 17.2%, and the intention to use mobile technologies ranged from 9.7% for web-based programs to 34.6% for apps.</p><p>Our results indicate a peak in research activity between 2014 and 2020, which may be influenced by the digital transformation of health care and the growing number of smoking cessation apps and other digital tools, which are often described as promising [<xref ref-type="bibr" rid="ref11">11</xref>,<xref ref-type="bibr" rid="ref18">18</xref>]. Digital tools are increasingly incorporated into public health strategies, including those of the WHO [<xref ref-type="bibr" rid="ref15">15</xref>,<xref ref-type="bibr" rid="ref16">16</xref>], and there is a discernible social shift in the popularity of digital platforms. However, since 2021, there has been a noticeable decline in available data, which may be due to delays in publication, shifting research priorities, or the disruptive impact of the COVID-19 pandemic on data collection and health research more broadly.</p><p>Although we were able to include more than 27 studies, those are characterized by high methodological variability, encompassing variations in target populations, settings and countries, study aims, sampling frames, outcome definitions, recall periods, and the types of mobile technology assessed. Furthermore, the quality of the majority of the included studies was found to be suboptimal, with particular concerns regarding the adequacy of the sample frame, the sampling strategy employed, and the methods used to assess the utilization of smoking cessation tools. A substantial number of studies have categorized a range of digital tools within broad terms (eg, web/mobile [<xref ref-type="bibr" rid="ref52">52</xref>], digital aids [<xref ref-type="bibr" rid="ref50">50</xref>], and online services [<xref ref-type="bibr" rid="ref56">56</xref>]), without clear differentiation, which has limited the interpretability of specific usage patterns. Furthermore, there is often an absence of reporting on clinical data (eg, comorbidities or tobacco dependence), general smoking patterns (eg, the number of cigarettes smoked per day or number of recent quit attempts), and data on individuals&#x2019; technical affinities (eg, mobile phone user patterns or use of other eHealth apps). These factors, however, are crucial in predicting the success of mobile technology in facilitating smoking cessation [<xref ref-type="bibr" rid="ref68">68</xref>]. Only 2 studies focusing on vaping cessation were identified, which is somewhat surprising given that trends in e-cigarette use have shown significant increases in recent years [<xref ref-type="bibr" rid="ref68">68</xref>], and digital interventions have been shown to be effective for vaping cessation [<xref ref-type="bibr" rid="ref23">23</xref>].</p><p>Overall, the prevalences of mobile technology use for smoking cessation ranged from 0% to 35.9%, with the majority of studies presenting prevalences from less than 15%. Regardless of the prevalence type, the internet was the most frequently used (up to 35.9%). However, in many studies [<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref26">26</xref>,<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref44">44</xref>-<xref ref-type="bibr" rid="ref46">46</xref>,<xref ref-type="bibr" rid="ref55">55</xref>,<xref ref-type="bibr" rid="ref58">58</xref>], &#x201C;internet use&#x201D; for smoking cessation was poorly defined and could include a variety of digital services that may not be considered stand-alone smoking cessation interventions, such as static informational websites, blogs, or online forums. Furthermore, it is often unclear whether access to web-only interventions occurred via mobile devices or desktop computers. However, it is evident that in the current era, over 90% of internet users utilize smartphones to access the internet [<xref ref-type="bibr" rid="ref35">35</xref>]. Nevertheless, it is important to recognize that this may not have been the case in previous years, and that a significant proportion of users, estimated at over 50%, still use laptops or desktop computers to access the internet [<xref ref-type="bibr" rid="ref35">35</xref>]. Surprisingly, the use of apps to support smoking cessation remains relatively low (lifetime prevalences 2.5%&#x2010;15.2%), despite the steadily increasing number of available smoking cessation apps [<xref ref-type="bibr" rid="ref69">69</xref>,<xref ref-type="bibr" rid="ref70">70</xref>]. By 2017, 177 unique apps relevant to smoking cessation were identified in the iPhone App Store, 139 in Google Play Store, 70 in the BlackBerry App Store, and 55 in the Windows Phone Store [<xref ref-type="bibr" rid="ref70">70</xref>]. Nevertheless, only 4% of the top applications recommended by leading app stores were found to have any scientific support [<xref ref-type="bibr" rid="ref71">71</xref>], which makes it challenging for users to identify an appropriate tool [<xref ref-type="bibr" rid="ref72">72</xref>]. Besides smoking cessation apps, social media platforms represent another promising approach, with a lifetime prevalence of use reaching up to 22.0%. Notwithstanding, only 2 studies [<xref ref-type="bibr" rid="ref24">24</xref>,<xref ref-type="bibr" rid="ref58">58</xref>] were identified that examined the prevalence of social media use for smoking cessation, so these numbers must be interpreted with caution. It is evident that social media platforms, which boast over 5 billion users worldwide and high penetration rates in Europe, ranging from 70.4% in Eastern Europe to 81.7% in Northern Europe [<xref ref-type="bibr" rid="ref73">73</xref>], have the capacity to reach a vast audience. Moreover, reviews have emphasized the feasibility, acceptability, and preliminary effectiveness of social media&#x2013;based interventions for smoking cessation [<xref ref-type="bibr" rid="ref74">74</xref>,<xref ref-type="bibr" rid="ref75">75</xref>]. However, retention rates in such interventions have been reported as low [<xref ref-type="bibr" rid="ref75">75</xref>], suggesting that social media often functions more as a by-product than as a sustained support tool. A substantial body of evidence supports the notion of digital interventions as a complementary treatment modality for smoking cessation [<xref ref-type="bibr" rid="ref17">17</xref>-<xref ref-type="bibr" rid="ref19">19</xref>,<xref ref-type="bibr" rid="ref70">70</xref>,<xref ref-type="bibr" rid="ref71">71</xref>,<xref ref-type="bibr" rid="ref76">76</xref>]. Nevertheless, there remains a paucity of high-quality data regarding the reach of such interventions, and the actual uptake remains low.</p><p>The use of mobile technologies for smoking cessation is influenced by a variety of factors, including cultural context, individual age, and socioeconomic status. In 2 of the included studies [<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref26">26</xref>], which were based on data from the Europe-wide EUREST-PLUS ITC (European Regulatory Science on Tobacco&#x2014;International Tobacco Control Project) Study on smoking behavior. Significant differences between countries were identified, and in both studies, the lowest reported use of mobile cessation technologies was found in Greece, where smoking prevalence remains the highest among European countries at 42%. Conversely, the higher prevalence of use was observed in countries with lower smoking prevalence, such as the United Kingdom and the Netherlands (both 12%) [<xref ref-type="bibr" rid="ref6">6</xref>]. This finding suggests that variations in national smoking norms and tobacco control policies, digital infrastructure, access to health care, and cultural norms may influence both the demand for and the implementation of digital tools. Socioeconomic status and age are also likely to be relevant. Younger persons &#x003C;40 years of age, compared to older people, showed a consistently higher use of apps, social media, and SMS text messaging programs [<xref ref-type="bibr" rid="ref26">26</xref>,<xref ref-type="bibr" rid="ref30">30</xref>,<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref46">46</xref>,<xref ref-type="bibr" rid="ref51">51</xref>]&#x2014;likely due to their high digital affinity [<xref ref-type="bibr" rid="ref77">77</xref>]. These patterns may be linked to differences in digital literacy, and especially digital health literacy [<xref ref-type="bibr" rid="ref78">78</xref>,<xref ref-type="bibr" rid="ref79">79</xref>], which has been described as a fundamental factor for enabling a successful digital transformation of health care systems and supporting informed decision-making in health contexts [<xref ref-type="bibr" rid="ref80">80</xref>]. This is particularly relevant for older populations, in which levels of digital competence tend to be lower [<xref ref-type="bibr" rid="ref81">81</xref>]. Particularly, low use was observed in vulnerable populations, such as financially disadvantaged groups (1%) or people with substance use disorders (0%) [<xref ref-type="bibr" rid="ref47">47</xref>,<xref ref-type="bibr" rid="ref55">55</xref>]&#x2014;possibly reflecting lower motivation to quit or additional barriers to accessing support. Overall, the intention to use mobile technologies for smoking cessation was up to 46.7%, which is somewhat higher than the actual use, indicating a general openness to digital smoking cessation tools. Consequently, efforts should focus less on developing new technologies and more on effectively delivering existing evidence-based tools to populations in need. Addressing disparities in access and engagement is essential to ensure equitable benefits and avoid reinforcing health inequalities. Continuous evaluation of user needs across diverse groups will help guide targeted strategies to enhance uptake and impact.</p></sec><sec id="s4-2"><title>Strengths and Limitations</title><p>To the best of our knowledge, this is the first systematic review to examine the prevalence of mobile technology use for smoking cessation. While it is possible that some studies were not identified due to the titles and abstracts of these studies not explicitly indicating the inclusion of mobile technologies, the comprehensive search strategy, which was supplemented by repeated forward and backward citation analyses, proved to be highly effective in identifying additional relevant studies.</p><p>However, it must be recognized that the present review has certain limitations. First, following the recommendations made during the peer-review process, it was decided to deviate from the established protocol and to narrow the primary focus to populations that smoke tobacco products. Studies assessing populations solely using noncombustible products were now reported only briefly as additional findings. Second, internet use was included as a form of mobile technology. However, a significant number of studies have not provided a detailed definition of internet use, which has resulted in difficulties in classifying it as a stand-alone smoking cessation tool. Moreover, although mobile devices, including smartphones, tablets, and laptops, have become prevalent instruments for accessing the internet in recent years, this has not always been the case. Consequently, the relevance of the internet as a digital smoking cessation aid may have been overestimated. Third, for better comparability, the review focused on high-income countries, which share broadly similar digital infrastructure, access to technology, tobacco control policies, and social norms around smoking; as a result, countries outside this category&#x2014;such as China, which has a high research output&#x2014;were not included. Furthermore, we exclusively extracted stratified prevalences on age and sex; yet, other diversity dimensions may also be important. No meta-analysis was conducted due to substantial heterogeneity across studies; yet, the findings provide a broad and current overview of existing prevalence data.</p></sec><sec id="s4-3"><title>Conclusion</title><p>The prevalence of mobile technology use for smoking cessation is relatively low, and there appears to be disparities in access and engagement, with older and socially disadvantaged groups showing lower prevalences of use. However, the intention to use mobile technologies for smoking cessation is relatively high, indicating a general openness toward such tools. The included studies, however, were characterized by high methodological variability and poor reporting, so the results must be interpreted with caution. It is recommended that future research employ more standardized definitions. Despite the pervasive availability of mobile technologies designed to facilitate smoking cessation and the existence of evidence regarding the efficacy of specific tools, this review indicates that the overall real-world impact of these tools remains limited. Consequently, efforts should concentrate more on evaluating user needs and delivering existing evidence-based tools to populations in need instead of developing new technologies.</p></sec></sec></body><back><ack><p>There was no use of generative artificial intelligence technology in the generation of text, figures, or other informational content of this manuscript.</p></ack><notes><sec><title>Funding</title><p>The authors gratefully acknowledge the support of the Leibniz ScienceCampus Bremen Digital Public health, which is jointly funded by the Leibniz Association (W72/2022), the Federal State of Bremen, and the Leibniz Institute for Prevention Research and Epidemiology&#x2013;BIPS. The funder did not influence the content of the study.</p></sec><sec><title>Data Availability</title><p>All data generated or analyzed during this study are included in this published article and its multimedia appendices.</p></sec></notes><fn-group><fn fn-type="con"><p>Conceptualization: ML (lead), FH (supporting), BB-H (supporting), JH (supporting)</p><p>Methodology: JH (lead), FH (equal), ML (supporting)</p><p>Formal analysis: ML (lead), JH (supporting)</p><p>Data curation: ML (lead), JO (supporting)</p><p>Investigation: ML (lead), JO (supporting), JH (supporting)</p><p>Writing&#x2014;original draft: ML (lead), FH (supporting), JH (supporting)</p><p>Writing&#x2014;review and editing: ML (lead), FH (supporting), JH (supporting), BB-H (supporting), JO (supporting)</p></fn><fn fn-type="conflict"><p>None declared.</p></fn></fn-group><glossary><title>Abbreviations</title><def-list><def-item><term id="abb1">CoCoPop</term><def><p>condition, context, population</p></def></def-item><def-item><term id="abb2">DEBRA </term><def><p>Deutsche Befragung zum Rauchverhalten</p></def></def-item><def-item><term id="abb3">e-cigarette</term><def><p>electronic cigarette</p></def></def-item><def-item><term id="abb4">EUREST-PLUS ITC</term><def><p>European Regulatory Science on Tobacco&#x2014;International Tobacco Control Project</p></def></def-item><def-item><term id="abb5">OECD</term><def><p>Organisation for Economic Co-operation and Development</p></def></def-item><def-item><term id="abb6">PRISMA</term><def><p>Preferred Reporting Items for Systematic Reviews and Meta-Analyses</p></def></def-item><def-item><term id="abb7">WHO</term><def><p>World Health Organization</p></def></def-item></def-list></glossary><ref-list><title>References</title><ref id="ref1"><label>1</label><nlm-citation citation-type="report"><article-title>WHO report on the global tobacco epidemic, 2025: warning about the dangers of tobacco</article-title><year>2025</year><access-date>2026-03-06</access-date><publisher-name>World Health Organization</publisher-name><comment><ext-link ext-link-type="uri" xlink:href="https://www.who.int/publications/i/item/9789240112063">https://www.who.int/publications/i/item/9789240112063</ext-link></comment></nlm-citation></ref><ref id="ref2"><label>2</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><collab>GBD 2019 Tobacco Collaborators</collab></person-group><article-title>Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990-2019: a systematic analysis from the Global Burden of Disease Study 2019</article-title><source>Lancet</source><year>2021</year><month>06</month><day>19</day><volume>397</volume><issue>10292</issue><fpage>2337</fpage><lpage>2360</lpage><pub-id pub-id-type="doi">10.1016/S0140-6736(21)01169-7</pub-id><pub-id pub-id-type="medline">34051883</pub-id></nlm-citation></ref><ref id="ref3"><label>3</label><nlm-citation citation-type="report"><article-title>WHO global report on trends in prevalence of tobacco use 2000&#x2013;2024 and projections 2025&#x2013;2030</article-title><year>2025</year><access-date>2026-03-06</access-date><publisher-name>World Health Organization</publisher-name><comment><ext-link ext-link-type="uri" xlink:href="https://www.who.int/publications/i/item/9789240116276">https://www.who.int/publications/i/item/9789240116276</ext-link></comment></nlm-citation></ref><ref id="ref4"><label>4</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Dai</surname><given-names>X</given-names> </name><name name-style="western"><surname>Gakidou</surname><given-names>E</given-names> </name><name name-style="western"><surname>Lopez</surname><given-names>AD</given-names> </name></person-group><article-title>Evolution of the global smoking epidemic over the past half century: strengthening the evidence base for policy action</article-title><source>Tob Control</source><year>2022</year><month>03</month><volume>31</volume><issue>2</issue><fpage>129</fpage><lpage>137</lpage><pub-id pub-id-type="doi">10.1136/tobaccocontrol-2021-056535</pub-id><pub-id pub-id-type="medline">35241576</pub-id></nlm-citation></ref><ref id="ref5"><label>5</label><nlm-citation citation-type="report"><person-group person-group-type="author"><collab>U.S. Department of Health and Human Services</collab></person-group><article-title>The health consequences of smoking&#x2014;50 years of progress: a report of the surgeon general</article-title><year>2014</year><access-date>2026-03-27</access-date><publisher-name>U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health</publisher-name><comment><ext-link ext-link-type="uri" xlink:href="https://www.ncbi.nlm.nih.gov/books/NBK179276/pdf/Bookshelf_NBK179276.pdf">https://www.ncbi.nlm.nih.gov/books/NBK179276/pdf/Bookshelf_NBK179276.pdf</ext-link></comment></nlm-citation></ref><ref id="ref6"><label>6</label><nlm-citation citation-type="report"><article-title>Attitudes of Europeans towards tobacco and related products</article-title><year>2024</year><access-date>2026-03-06</access-date><publisher-name>European Commission</publisher-name><comment><ext-link ext-link-type="uri" xlink:href="https://europa.eu/eurobarometer/surveys/detail/2995">https://europa.eu/eurobarometer/surveys/detail/2995</ext-link></comment></nlm-citation></ref><ref id="ref7"><label>7</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>VanFrank</surname><given-names>B</given-names> </name><name name-style="western"><surname>Malarcher</surname><given-names>A</given-names> </name><name name-style="western"><surname>Cornelius</surname><given-names>ME</given-names> </name><name name-style="western"><surname>Schecter</surname><given-names>A</given-names> </name><name name-style="western"><surname>Jamal</surname><given-names>A</given-names> </name><name name-style="western"><surname>Tynan</surname><given-names>M</given-names> </name></person-group><article-title>Adult smoking cessation - United States, 2022</article-title><source>MMWR Morb Mortal Wkly Rep</source><year>2024</year><month>07</month><day>25</day><volume>73</volume><issue>29</issue><fpage>633</fpage><lpage>641</lpage><pub-id pub-id-type="doi">10.15585/mmwr.mm7329a1</pub-id><pub-id pub-id-type="medline">39052529</pub-id></nlm-citation></ref><ref id="ref8"><label>8</label><nlm-citation citation-type="book"><person-group person-group-type="author"><name name-style="western"><surname>Taylor</surname><given-names>AH</given-names> </name><name name-style="western"><surname>Ussher</surname><given-names>M</given-names> </name></person-group><article-title>Physical activity as an aid in smoking cessation</article-title><source>Routledge Handbook of Physical Activity and Mental Health</source><year>2013</year><publisher-name>Routledge</publisher-name><fpage>451</fpage><lpage>464</lpage><pub-id pub-id-type="doi">10.4324/9781003423430-41</pub-id><pub-id pub-id-type="other">9780203132678</pub-id></nlm-citation></ref><ref id="ref9"><label>9</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Kotz</surname><given-names>D</given-names> </name><name name-style="western"><surname>Batra</surname><given-names>A</given-names> </name><name name-style="western"><surname>Kastaun</surname><given-names>S</given-names> </name></person-group><article-title>Smoking cessation attempts and common strategies employed</article-title><source>Dtsch Arztebl Int</source><year>2020</year><month>01</month><day>6</day><volume>117</volume><issue>1-2</issue><fpage>7</fpage><lpage>13</lpage><pub-id pub-id-type="doi">10.3238/arztebl.2020.0007</pub-id><pub-id pub-id-type="medline">32008606</pub-id></nlm-citation></ref><ref id="ref10"><label>10</label><nlm-citation citation-type="report"><article-title>Measuring digital development facts and figures 2025</article-title><year>2025</year><access-date>2026-03-06</access-date><publisher-name>International Telecommunication Union (ITU)</publisher-name><comment><ext-link ext-link-type="uri" xlink:href="https://www.itu.int/dms_pub/itu-d/opb/ind/d-ind-ict_mdd-2025-3-pdf-e.pdf">https://www.itu.int/dms_pub/itu-d/opb/ind/d-ind-ict_mdd-2025-3-pdf-e.pdf</ext-link></comment></nlm-citation></ref><ref id="ref11"><label>11</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Whittaker</surname><given-names>R</given-names> </name><name name-style="western"><surname>McRobbie</surname><given-names>H</given-names> </name><name name-style="western"><surname>Bullen</surname><given-names>C</given-names> </name><name name-style="western"><surname>Rodgers</surname><given-names>A</given-names> </name><name name-style="western"><surname>Gu</surname><given-names>Y</given-names> </name></person-group><article-title>Mobile phone-based interventions for smoking cessation</article-title><source>Cochrane Database Syst Rev</source><year>2016</year><month>04</month><day>10</day><volume>4</volume><issue>4</issue><fpage>CD006611</fpage><pub-id pub-id-type="doi">10.1002/14651858.CD006611.pub4</pub-id><pub-id pub-id-type="medline">27060875</pub-id></nlm-citation></ref><ref id="ref12"><label>12</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Wienert</surname><given-names>J</given-names> </name><name name-style="western"><surname>Jahnel</surname><given-names>T</given-names> </name><name name-style="western"><surname>Maa&#x00DF;</surname><given-names>L</given-names> </name></person-group><article-title>What are digital public health interventions? First steps toward a definition and an intervention classification framework</article-title><source>J Med Internet Res</source><year>2022</year><month>06</month><day>28</day><volume>24</volume><issue>6</issue><fpage>e31921</fpage><pub-id pub-id-type="doi">10.2196/31921</pub-id><pub-id pub-id-type="medline">35763320</pub-id></nlm-citation></ref><ref id="ref13"><label>13</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Liu</surname><given-names>S</given-names> </name><name name-style="western"><surname>Ma</surname><given-names>J</given-names> </name><name name-style="western"><surname>Sun</surname><given-names>M</given-names> </name><name name-style="western"><surname>Zhang</surname><given-names>C</given-names> </name><name name-style="western"><surname>Gao</surname><given-names>Y</given-names> </name><name name-style="western"><surname>Xu</surname><given-names>J</given-names> </name></person-group><article-title>Mapping the landscape of digital health intervention strategies: 25-year synthesis</article-title><source>J Med Internet Res</source><year>2025</year><month>01</month><day>13</day><volume>27</volume><fpage>e59027</fpage><pub-id pub-id-type="doi">10.2196/59027</pub-id><pub-id pub-id-type="medline">39804697</pub-id></nlm-citation></ref><ref id="ref14"><label>14</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Alsaqqa</surname><given-names>HH</given-names> </name><name name-style="western"><surname>Alwawi</surname><given-names>A</given-names> </name></person-group><article-title>Digital intervention for public health: searching for implementing characteristics, concepts and recommendations: scoping review</article-title><source>Front Public Health</source><year>2023</year><volume>11</volume><fpage>1142443</fpage><pub-id pub-id-type="doi">10.3389/fpubh.2023.1142443</pub-id><pub-id pub-id-type="medline">37790710</pub-id></nlm-citation></ref><ref id="ref15"><label>15</label><nlm-citation citation-type="report"><article-title>Global strategy on digital health 2020-2025</article-title><year>2021</year><access-date>2026-03-06</access-date><publisher-name>World Health Organization</publisher-name><comment><ext-link ext-link-type="uri" xlink:href="https://iris.who.int/server/api/core/bitstreams/1f4d4a08-b20d-4c36-9148-a59429ac3477/content">https://iris.who.int/server/api/core/bitstreams/1f4d4a08-b20d-4c36-9148-a59429ac3477/content</ext-link></comment></nlm-citation></ref><ref id="ref16"><label>16</label><nlm-citation citation-type="report"><article-title>WHO clinical treatment guideline for tobacco cessation in adults</article-title><year>2024</year><access-date>2026-03-06</access-date><publisher-name>World Health Organization</publisher-name><comment><ext-link ext-link-type="uri" xlink:href="https://iris.who.int/server/api/core/bitstreams/2deb01bc-1be9-4e9c-b113-5efbb67780c7/content">https://iris.who.int/server/api/core/bitstreams/2deb01bc-1be9-4e9c-b113-5efbb67780c7/content</ext-link></comment></nlm-citation></ref><ref id="ref17"><label>17</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Fang</surname><given-names>YE</given-names> </name><name name-style="western"><surname>Zhang</surname><given-names>Z</given-names> </name><name name-style="western"><surname>Wang</surname><given-names>R</given-names> </name><etal/></person-group><article-title>Effectiveness of eHealth smoking cessation interventions: systematic review and meta-analysis</article-title><source>J Med Internet Res</source><year>2023</year><month>07</month><day>28</day><volume>25</volume><fpage>e45111</fpage><pub-id pub-id-type="doi">10.2196/45111</pub-id><pub-id pub-id-type="medline">37505802</pub-id></nlm-citation></ref><ref id="ref18"><label>18</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Rushender</surname><given-names>R</given-names> </name><name name-style="western"><surname>Logaraj</surname><given-names>M</given-names> </name><name name-style="western"><surname>Krishnamoorthy</surname><given-names>Y</given-names> </name></person-group><article-title>Effectiveness of mobile phone applications for tobacco cessation: an umbrella review</article-title><source>Drug Alcohol Depend</source><year>2024</year><month>10</month><day>1</day><volume>263</volume><fpage>112425</fpage><pub-id pub-id-type="doi">10.1016/j.drugalcdep.2024.112425</pub-id><pub-id pub-id-type="medline">39216199</pub-id></nlm-citation></ref><ref id="ref19"><label>19</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Guo</surname><given-names>YQ</given-names> </name><name name-style="western"><surname>Chen</surname><given-names>Y</given-names> </name><name name-style="western"><surname>Dabbs</surname><given-names>AD</given-names> </name><name name-style="western"><surname>Wu</surname><given-names>Y</given-names> </name></person-group><article-title>The effectiveness of smartphone app-based interventions for assisting smoking cessation: systematic review and meta-analysis</article-title><source>J Med Internet Res</source><year>2023</year><month>04</month><day>20</day><volume>25</volume><fpage>e43242</fpage><pub-id pub-id-type="doi">10.2196/43242</pub-id><pub-id pub-id-type="medline">37079352</pub-id></nlm-citation></ref><ref id="ref20"><label>20</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Amin</surname><given-names>S</given-names> </name><name name-style="western"><surname>Billah</surname><given-names>MS</given-names> </name><name name-style="western"><surname>Jahra Jarin</surname><given-names>E</given-names> </name></person-group><article-title>A systematic review of digital intervention of smoking abstinence during the COVID-19 era</article-title><source>Int J Health Sci Res</source><year>2024</year><volume>14</volume><issue>3</issue><fpage>35</fpage><lpage>42</lpage><pub-id pub-id-type="doi">10.52403/ijhsr.20240307</pub-id></nlm-citation></ref><ref id="ref21"><label>21</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Li</surname><given-names>S</given-names> </name><name name-style="western"><surname>Li</surname><given-names>Y</given-names> </name><name name-style="western"><surname>Xu</surname><given-names>C</given-names> </name><etal/></person-group><article-title>Efficacy of digital interventions for smoking cessation by type and method: a systematic review and network meta-analysis</article-title><source>Nat Hum Behav</source><year>2025</year><month>10</month><volume>9</volume><issue>10</issue><fpage>2054</fpage><lpage>2065</lpage><pub-id pub-id-type="doi">10.1038/s41562-025-02295-2</pub-id><pub-id pub-id-type="medline">40897803</pub-id></nlm-citation></ref><ref id="ref22"><label>22</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Di Palo</surname><given-names>MP</given-names> </name><name name-style="western"><surname>Di Spirito</surname><given-names>F</given-names> </name><name name-style="western"><surname>Garofano</surname><given-names>M</given-names> </name><etal/></person-group><article-title>Effectiveness and adherence of standalone digital tobacco cessation modalities: a systematic review of systematic reviews</article-title><source>Healthcare (Basel)</source><year>2025</year><month>08</month><day>26</day><volume>13</volume><issue>17</issue><fpage>2125</fpage><pub-id pub-id-type="doi">10.3390/healthcare13172125</pub-id><pub-id pub-id-type="medline">40941478</pub-id></nlm-citation></ref><ref id="ref23"><label>23</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Bhadania</surname><given-names>M</given-names> </name><name name-style="western"><surname>Yadav</surname><given-names>S</given-names> </name><name name-style="western"><surname>Mathur</surname><given-names>A</given-names> </name><name name-style="western"><surname>Acharya</surname><given-names>A</given-names> </name><name name-style="western"><surname>Mehta</surname><given-names>V</given-names> </name></person-group><article-title>Mapping the effectiveness of digital health interventions in promoting electronic cigarette cessation: a systematic review and meta-analysis of randomized controlled trials</article-title><source>BMC Public Health</source><year>2025</year><month>10</month><day>28</day><volume>25</volume><issue>1</issue><fpage>3645</fpage><pub-id pub-id-type="doi">10.1186/s12889-025-24990-5</pub-id><pub-id pub-id-type="medline">41152828</pub-id></nlm-citation></ref><ref id="ref24"><label>24</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Borrelli</surname><given-names>B</given-names> </name><name name-style="western"><surname>Bartlett</surname><given-names>YK</given-names> </name><name name-style="western"><surname>Tooley</surname><given-names>E</given-names> </name><name name-style="western"><surname>Armitage</surname><given-names>CJ</given-names> </name><name name-style="western"><surname>Wearden</surname><given-names>A</given-names> </name></person-group><article-title>Prevalence and frequency of mHealth and eHealth use among US and UK smokers and differences by motivation to quit</article-title><source>J Med Internet Res</source><year>2015</year><month>07</month><day>4</day><volume>17</volume><issue>7</issue><fpage>e164</fpage><pub-id pub-id-type="doi">10.2196/jmir.4420</pub-id><pub-id pub-id-type="medline">26149323</pub-id></nlm-citation></ref><ref id="ref25"><label>25</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Papadakis</surname><given-names>S</given-names> </name><name name-style="western"><surname>Katsaounou</surname><given-names>P</given-names> </name><name name-style="western"><surname>Kyriakos</surname><given-names>CN</given-names> </name><etal/></person-group><article-title>Quitting behaviours and cessation methods used in eight European Countries in 2018: findings from the EUREST-PLUS ITC Europe Surveys</article-title><source>Eur J Public Health</source><year>2020</year><month>07</month><day>1</day><volume>30</volume><issue>Suppl_3</issue><fpage>iii26</fpage><lpage>iii33</lpage><pub-id pub-id-type="doi">10.1093/eurpub/ckaa082</pub-id><pub-id pub-id-type="medline">32918825</pub-id></nlm-citation></ref><ref id="ref26"><label>26</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Hummel</surname><given-names>K</given-names> </name><name name-style="western"><surname>Nagelhout</surname><given-names>GE</given-names> </name><name name-style="western"><surname>Fong</surname><given-names>GT</given-names> </name><etal/></person-group><article-title>Quitting activity and use of cessation assistance reported by smokers in eight European countries: findings from the EUREST-PLUS ITC Europe Surveys</article-title><source>Tob Induc Dis</source><year>2018</year><volume>16</volume><issue>Suppl 2</issue><fpage>1</fpage><lpage>17</lpage><pub-id pub-id-type="doi">10.18332/tid/98912</pub-id><pub-id pub-id-type="medline">31363422</pub-id></nlm-citation></ref><ref id="ref27"><label>27</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Strecher</surname><given-names>VJ</given-names> </name><name name-style="western"><surname>McClure</surname><given-names>J</given-names> </name><name name-style="western"><surname>Alexander</surname><given-names>G</given-names> </name><etal/></person-group><article-title>The role of engagement in a tailored web-based smoking cessation program: randomized controlled trial</article-title><source>J Med Internet Res</source><year>2008</year><month>11</month><day>4</day><volume>10</volume><issue>5</issue><fpage>e36</fpage><pub-id pub-id-type="doi">10.2196/jmir.1002</pub-id><pub-id pub-id-type="medline">18984557</pub-id></nlm-citation></ref><ref id="ref28"><label>28</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Zeng</surname><given-names>EY</given-names> </name><name name-style="western"><surname>Vilardaga</surname><given-names>R</given-names> </name><name name-style="western"><surname>Heffner</surname><given-names>JL</given-names> </name><name name-style="western"><surname>Mull</surname><given-names>KE</given-names> </name><name name-style="western"><surname>Bricker</surname><given-names>JB</given-names> </name></person-group><article-title>Predictors of utilization of a novel smoking cessation smartphone app</article-title><source>Telemed J E Health</source><year>2015</year><month>12</month><volume>21</volume><issue>12</issue><fpage>998</fpage><lpage>1004</lpage><pub-id pub-id-type="doi">10.1089/tmj.2014.0232</pub-id><pub-id pub-id-type="medline">26171733</pub-id></nlm-citation></ref><ref id="ref29"><label>29</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Wangberg</surname><given-names>SC</given-names> </name><name name-style="western"><surname>Bergmo</surname><given-names>TS</given-names> </name><name name-style="western"><surname>Johnsen</surname><given-names>JAK</given-names> </name></person-group><article-title>Adherence in internet-based interventions</article-title><source>Patient Prefer Adherence</source><year>2008</year><month>02</month><day>2</day><volume>2</volume><fpage>57</fpage><lpage>65</lpage><pub-id pub-id-type="medline">19920945</pub-id></nlm-citation></ref><ref id="ref30"><label>30</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Jackson</surname><given-names>SE</given-names> </name><name name-style="western"><surname>Kotz</surname><given-names>D</given-names> </name><name name-style="western"><surname>West</surname><given-names>R</given-names> </name><name name-style="western"><surname>Brown</surname><given-names>J</given-names> </name></person-group><article-title>Moderators of real-world effectiveness of smoking cessation aids: a population study</article-title><source>Addiction</source><year>2019</year><month>09</month><volume>114</volume><issue>9</issue><fpage>1627</fpage><lpage>1638</lpage><pub-id pub-id-type="doi">10.1111/add.14656</pub-id><pub-id pub-id-type="medline">31117151</pub-id></nlm-citation></ref><ref id="ref31"><label>31</label><nlm-citation citation-type="book"><person-group person-group-type="author"><name name-style="western"><surname>Aromataris</surname><given-names>E</given-names> </name><name name-style="western"><surname>Lockwood</surname><given-names>C</given-names> </name><name name-style="western"><surname>Porritt</surname><given-names>K</given-names> </name><name name-style="western"><surname>Pilla</surname><given-names>B</given-names> </name><name name-style="western"><surname>Jordan</surname><given-names>Z</given-names> </name></person-group><source>JBI Manual for Evidence Synthesis</source><year>2024</year><access-date>2026-03-27</access-date><publisher-name>Joanna Briggs Institute</publisher-name><comment><ext-link ext-link-type="uri" xlink:href="https://jbi-global-wiki.refined.site/space/MANUAL">https://jbi-global-wiki.refined.site/space/MANUAL</ext-link></comment><pub-id pub-id-type="other">978-0-6488488-2-0</pub-id></nlm-citation></ref><ref id="ref32"><label>32</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Page</surname><given-names>MJ</given-names> </name><name name-style="western"><surname>McKenzie</surname><given-names>JE</given-names> </name><name name-style="western"><surname>Bossuyt</surname><given-names>PM</given-names> </name><etal/></person-group><article-title>The PRISMA 2020 statement: an updated guideline for reporting systematic reviews</article-title><source>BMJ</source><year>2021</year><month>03</month><day>29</day><volume>372</volume><fpage>n71</fpage><pub-id pub-id-type="doi">10.1136/bmj.n71</pub-id><pub-id pub-id-type="medline">33782057</pub-id></nlm-citation></ref><ref id="ref33"><label>33</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Hirt</surname><given-names>J</given-names> </name><name name-style="western"><surname>Nordhausen</surname><given-names>T</given-names> </name><name name-style="western"><surname>Fuerst</surname><given-names>T</given-names> </name><name name-style="western"><surname>Ewald</surname><given-names>H</given-names> </name><name name-style="western"><surname>Appenzeller-Herzog</surname><given-names>C</given-names> </name><collab>TARCiS study group</collab></person-group><article-title>Guidance on terminology, application, and reporting of citation searching: the TARCiS statement</article-title><source>BMJ</source><year>2024</year><month>05</month><day>9</day><volume>385</volume><fpage>e078384</fpage><pub-id pub-id-type="doi">10.1136/bmj-2023-078384</pub-id><pub-id pub-id-type="medline">38724089</pub-id></nlm-citation></ref><ref id="ref34"><label>34</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Munn</surname><given-names>Z</given-names> </name><name name-style="western"><surname>Stern</surname><given-names>C</given-names> </name><name name-style="western"><surname>Aromataris</surname><given-names>E</given-names> </name><name name-style="western"><surname>Lockwood</surname><given-names>C</given-names> </name><name name-style="western"><surname>Jordan</surname><given-names>Z</given-names> </name></person-group><article-title>What kind of systematic review should I conduct? A proposed typology and guidance for systematic reviewers in the medical and health sciences</article-title><source>BMC Med Res Methodol</source><year>2018</year><month>01</month><day>10</day><volume>18</volume><issue>1</issue><fpage>5</fpage><pub-id pub-id-type="doi">10.1186/s12874-017-0468-4</pub-id><pub-id pub-id-type="medline">29316881</pub-id></nlm-citation></ref><ref id="ref35"><label>35</label><nlm-citation citation-type="web"><article-title>Digital 2026 global overview report</article-title><source>We Are Social</source><access-date>2026-03-06</access-date><comment><ext-link ext-link-type="uri" xlink:href="https://wearesocial.com/uk/blog/2025/10/digital-2026-global-overview-report/">https://wearesocial.com/uk/blog/2025/10/digital-2026-global-overview-report/</ext-link></comment></nlm-citation></ref><ref id="ref36"><label>36</label><nlm-citation citation-type="web"><article-title>ODA recipients: countries, territories, and international organisations</article-title><source>Organisation for Economic Co&#x2011;operation and Development</source><access-date>2026-03-06</access-date><comment><ext-link ext-link-type="uri" xlink:href="https://www.oecd.org/en/topics/sub-issues/oda-eligibility-and-conditions/dac-list-of-oda-recipients.html">https://www.oecd.org/en/topics/sub-issues/oda-eligibility-and-conditions/dac-list-of-oda-recipients.html</ext-link></comment></nlm-citation></ref><ref id="ref37"><label>37</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Munn</surname><given-names>Z</given-names> </name><name name-style="western"><surname>Moola</surname><given-names>S</given-names> </name><name name-style="western"><surname>Lisy</surname><given-names>K</given-names> </name><name name-style="western"><surname>Riitano</surname><given-names>D</given-names> </name><name name-style="western"><surname>Tufanaru</surname><given-names>C</given-names> </name></person-group><article-title>Methodological guidance for systematic reviews of observational epidemiological studies reporting prevalence and cumulative incidence data</article-title><source>Int J Evid Based Healthc</source><year>2015</year><month>09</month><volume>13</volume><issue>3</issue><fpage>147</fpage><lpage>153</lpage><pub-id pub-id-type="doi">10.1097/XEB.0000000000000054</pub-id><pub-id pub-id-type="medline">26317388</pub-id></nlm-citation></ref><ref id="ref38"><label>38</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Hoffmann</surname><given-names>F</given-names> </name><name name-style="western"><surname>Eggers</surname><given-names>D</given-names> </name><name name-style="western"><surname>Pieper</surname><given-names>D</given-names> </name><name name-style="western"><surname>Zeeb</surname><given-names>H</given-names> </name><name name-style="western"><surname>Allers</surname><given-names>K</given-names> </name></person-group><article-title>An observational study found large methodological heterogeneity in systematic reviews addressing prevalence and cumulative incidence</article-title><source>J Clin Epidemiol</source><year>2020</year><month>03</month><volume>119</volume><fpage>92</fpage><lpage>99</lpage><pub-id pub-id-type="doi">10.1016/j.jclinepi.2019.12.003</pub-id><pub-id pub-id-type="medline">31809847</pub-id></nlm-citation></ref><ref id="ref39"><label>39</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Caraballo</surname><given-names>RS</given-names> </name><name name-style="western"><surname>Shafer</surname><given-names>PR</given-names> </name><name name-style="western"><surname>Patel</surname><given-names>D</given-names> </name><name name-style="western"><surname>Davis</surname><given-names>KC</given-names> </name><name name-style="western"><surname>McAfee</surname><given-names>TA</given-names> </name></person-group><article-title>Quit methods used by US adult cigarette smokers, 2014-2016</article-title><source>Prev Chronic Dis</source><year>2017</year><month>04</month><day>13</day><volume>14</volume><fpage>E32</fpage><pub-id pub-id-type="doi">10.5888/pcd14.160600</pub-id><pub-id pub-id-type="medline">28409740</pub-id></nlm-citation></ref><ref id="ref40"><label>40</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Curry</surname><given-names>SJ</given-names> </name><name name-style="western"><surname>Sporer</surname><given-names>AK</given-names> </name><name name-style="western"><surname>Pugach</surname><given-names>O</given-names> </name><name name-style="western"><surname>Campbell</surname><given-names>RT</given-names> </name><name name-style="western"><surname>Emery</surname><given-names>S</given-names> </name></person-group><article-title>Use of tobacco cessation treatments among young adult smokers: 2005 National Health Interview Survey</article-title><source>Am J Public Health</source><year>2007</year><month>08</month><volume>97</volume><issue>8</issue><fpage>1464</fpage><lpage>1469</lpage><pub-id pub-id-type="doi">10.2105/AJPH.2006.103788</pub-id><pub-id pub-id-type="medline">17600243</pub-id></nlm-citation></ref><ref id="ref41"><label>41</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Graham</surname><given-names>EL</given-names> </name><name name-style="western"><surname>Koralnik</surname><given-names>IJ</given-names> </name><name name-style="western"><surname>Liotta</surname><given-names>EM</given-names> </name></person-group><article-title>Therapeutic approaches to the neurologic manifestations of COVID-19</article-title><source>Neurotherapeutics</source><year>2022</year><month>09</month><volume>19</volume><issue>5</issue><fpage>1435</fpage><lpage>1466</lpage><pub-id pub-id-type="doi">10.1007/s13311-022-01267-y</pub-id><pub-id pub-id-type="medline">35861926</pub-id></nlm-citation></ref><ref id="ref42"><label>42</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Moon</surname><given-names>J</given-names> </name><name name-style="western"><surname>Rigg</surname><given-names>JS</given-names> </name><name name-style="western"><surname>Smith</surname><given-names>JE</given-names> </name></person-group><article-title>Korean American smokers' perspectives on mobile smoking cessation applications</article-title><source>Tob Use Insights</source><year>2020</year><volume>13</volume><fpage>1179173X20972384</fpage><pub-id pub-id-type="doi">10.1177/1179173X20972384</pub-id><pub-id pub-id-type="medline">33402856</pub-id></nlm-citation></ref><ref id="ref43"><label>43</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Oliver</surname><given-names>JA</given-names> </name><name name-style="western"><surname>Hallyburton</surname><given-names>MB</given-names> </name><name name-style="western"><surname>Pacek</surname><given-names>LR</given-names> </name><etal/></person-group><article-title>What do smokers want in a smartphone-based cessation application?</article-title><source>Nicotine Tob Res</source><year>2018</year><month>11</month><day>15</day><volume>20</volume><issue>12</issue><fpage>1507</fpage><lpage>1514</lpage><pub-id pub-id-type="doi">10.1093/ntr/ntx171</pub-id><pub-id pub-id-type="medline">29065202</pub-id></nlm-citation></ref><ref id="ref44"><label>44</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Patterson</surname><given-names>JG</given-names> </name><name name-style="western"><surname>Hinton</surname><given-names>A</given-names> </name><name name-style="western"><surname>Cooper</surname><given-names>SE</given-names> </name><name name-style="western"><surname>Wewers</surname><given-names>ME</given-names> </name></person-group><article-title>Differences in quit attempts, successful quits, methods, and motivations in a longitudinal cohort of adult tobacco users by sexual orientation</article-title><source>Nicotine Tob Res</source><year>2021</year><month>10</month><day>7</day><volume>23</volume><issue>11</issue><fpage>1952</fpage><lpage>1957</lpage><pub-id pub-id-type="doi">10.1093/ntr/ntab116</pub-id><pub-id pub-id-type="medline">34060633</pub-id></nlm-citation></ref><ref id="ref45"><label>45</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Ramo</surname><given-names>DE</given-names> </name><name name-style="western"><surname>Liu</surname><given-names>H</given-names> </name><name name-style="western"><surname>Prochaska</surname><given-names>JJ</given-names> </name></person-group><article-title>A mixed-methods study of young adults&#x2019; receptivity to using Facebook for smoking cessation: if you build it, will they come?</article-title><source>Am J Health Promot</source><year>2015</year><volume>29</volume><issue>4</issue><fpage>e126</fpage><lpage>35</lpage><pub-id pub-id-type="doi">10.4278/ajhp.130326-QUAL-128</pub-id><pub-id pub-id-type="medline">24575728</pub-id></nlm-citation></ref><ref id="ref46"><label>46</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Thrul</surname><given-names>J</given-names> </name><name name-style="western"><surname>Riehm</surname><given-names>KE</given-names> </name><name name-style="western"><surname>Cohen</surname><given-names>JE</given-names> </name><name name-style="western"><surname>Alexander</surname><given-names>GC</given-names> </name><name name-style="western"><surname>Vernick</surname><given-names>JS</given-names> </name><name name-style="western"><surname>Mojtabai</surname><given-names>R</given-names> </name></person-group><article-title>Tobacco control policies and smoking cessation treatment utilization: a moderated mediation analysis</article-title><source>PLoS ONE</source><year>2021</year><volume>16</volume><issue>8</issue><fpage>e0241512</fpage><pub-id pub-id-type="doi">10.1371/journal.pone.0241512</pub-id><pub-id pub-id-type="medline">34460821</pub-id></nlm-citation></ref><ref id="ref47"><label>47</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Tofighi</surname><given-names>B</given-names> </name><name name-style="western"><surname>Lee</surname><given-names>JD</given-names> </name><name name-style="western"><surname>Sherman</surname><given-names>S</given-names> </name><name name-style="western"><surname>Schatz</surname><given-names>D</given-names> </name><name name-style="western"><surname>El-Shahawy</surname><given-names>O</given-names> </name></person-group><article-title>Smoking patterns and preferences for technology assisted smoking cessation interventions among adults with opioid and alcohol use disorders</article-title><source>J Subst Use</source><year>2019</year><volume>24</volume><issue>6</issue><fpage>660</fpage><lpage>665</lpage><pub-id pub-id-type="doi">10.1080/14659891.2019.1642407</pub-id><pub-id pub-id-type="medline">32952442</pub-id></nlm-citation></ref><ref id="ref48"><label>48</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Jackson</surname><given-names>SE</given-names> </name><name name-style="western"><surname>Cox</surname><given-names>S</given-names> </name><name name-style="western"><surname>Shahab</surname><given-names>L</given-names> </name><name name-style="western"><surname>Brown</surname><given-names>J</given-names> </name></person-group><article-title>Prevalence of use and real-world effectiveness of smoking cessation aids during the COVID-19 pandemic: a representative study of smokers in England</article-title><source>Addiction</source><year>2022</year><month>09</month><volume>117</volume><issue>9</issue><fpage>2504</fpage><lpage>2514</lpage><pub-id pub-id-type="doi">10.1111/add.15903</pub-id><pub-id pub-id-type="medline">35491743</pub-id></nlm-citation></ref><ref id="ref49"><label>49</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Jackson</surname><given-names>SE</given-names> </name><name name-style="western"><surname>Brown</surname><given-names>J</given-names> </name><name name-style="western"><surname>Buss</surname><given-names>V</given-names> </name><name name-style="western"><surname>Shahab</surname><given-names>L</given-names> </name></person-group><article-title>Prevalence of popular smoking cessation aids in England and associations with quit success</article-title><source>JAMA Netw Open</source><year>2025</year><month>01</month><day>2</day><volume>8</volume><issue>1</issue><fpage>e2454962</fpage><pub-id pub-id-type="doi">10.1001/jamanetworkopen.2024.54962</pub-id><pub-id pub-id-type="medline">39821398</pub-id></nlm-citation></ref><ref id="ref50"><label>50</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Perski</surname><given-names>O</given-names> </name><name name-style="western"><surname>West</surname><given-names>R</given-names> </name><name name-style="western"><surname>Brown</surname><given-names>J</given-names> </name></person-group><article-title>Estimated failure to report unsuccessful quit attempts by type of cessation aid: a population survey of smokers in England</article-title><source>J Smok Cessat</source><year>2022</year><volume>2022</volume><fpage>5572480</fpage><pub-id pub-id-type="doi">10.1155/2022/5572480</pub-id><pub-id pub-id-type="medline">36568905</pub-id></nlm-citation></ref><ref id="ref51"><label>51</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Lund</surname><given-names>I</given-names> </name><name name-style="western"><surname>Lund</surname><given-names>M</given-names> </name></person-group><article-title>Quit smoking: methods and outcomes for Norwegian adults</article-title><source>Discov Soc Sci Health</source><year>2023</year><volume>3</volume><fpage>12</fpage><pub-id pub-id-type="doi">10.1007/s44155-023-00043-3</pub-id></nlm-citation></ref><ref id="ref52"><label>52</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Lund</surname><given-names>M</given-names> </name><name name-style="western"><surname>Lund</surname><given-names>I</given-names> </name></person-group><article-title>Smoking cessation aids and strategies: a population-based survey of former and current smokers in Norway</article-title><source>BMC Public Health</source><year>2022</year><month>03</month><day>31</day><volume>22</volume><issue>1</issue><fpage>631</fpage><pub-id pub-id-type="doi">10.1186/s12889-022-13032-z</pub-id><pub-id pub-id-type="medline">35361172</pub-id></nlm-citation></ref><ref id="ref53"><label>53</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Bottorff</surname><given-names>JL</given-names> </name><name name-style="western"><surname>Oliffe</surname><given-names>JL</given-names> </name><name name-style="western"><surname>Sarbit</surname><given-names>G</given-names> </name><etal/></person-group><article-title>Evaluation of quitnow men: an online, men-centered smoking cessation intervention</article-title><source>J Med Internet Res</source><year>2016</year><month>04</month><day>20</day><volume>18</volume><issue>4</issue><fpage>e83</fpage><pub-id pub-id-type="doi">10.2196/jmir.5076</pub-id><pub-id pub-id-type="medline">27097991</pub-id></nlm-citation></ref><ref id="ref54"><label>54</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Jayakumar</surname><given-names>N</given-names> </name><name name-style="western"><surname>Chaiton</surname><given-names>M</given-names> </name><name name-style="western"><surname>Zhang</surname><given-names>B</given-names> </name><name name-style="western"><surname>Selby</surname><given-names>P</given-names> </name><name name-style="western"><surname>Schwartz</surname><given-names>R</given-names> </name></person-group><article-title>Sex differences in use of smoking cessation services and resources: a real-world study</article-title><source>Tob Use Insights</source><year>2020</year><volume>13</volume><fpage>1179173X20901500</fpage><pub-id pub-id-type="doi">10.1177/1179173X20901500</pub-id><pub-id pub-id-type="medline">32030067</pub-id></nlm-citation></ref><ref id="ref55"><label>55</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Twyman</surname><given-names>L</given-names> </name><name name-style="western"><surname>Bonevski</surname><given-names>B</given-names> </name><name name-style="western"><surname>Paul</surname><given-names>C</given-names> </name><etal/></person-group><article-title>What factors are associated with abstinence amongst socioeconomically disadvantaged smokers? A cross-sectional survey of use of cessation aids and quitting approach</article-title><source>Drug Alcohol Rev</source><year>2018</year><month>02</month><volume>37</volume><issue>2</issue><fpage>170</fpage><lpage>179</lpage><pub-id pub-id-type="doi">10.1111/dar.12561</pub-id><pub-id pub-id-type="medline">28616900</pub-id></nlm-citation></ref><ref id="ref56"><label>56</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Li</surname><given-names>W</given-names> </name><name name-style="western"><surname>Paul</surname><given-names>CL</given-names> </name><name name-style="western"><surname>Baker</surname><given-names>AL</given-names> </name><etal/></person-group><article-title>Quit attempts, use of smoking cessation treatments and quitting intention among treatment seekers in rural areas</article-title><source>J Subst Use Addict Treat</source><year>2025</year><month>02</month><volume>169</volume><fpage>209603</fpage><pub-id pub-id-type="doi">10.1016/j.josat.2024.209603</pub-id><pub-id pub-id-type="medline">39672339</pub-id></nlm-citation></ref><ref id="ref57"><label>57</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Chevalking</surname><given-names>SL</given-names> </name><name name-style="western"><surname>Ben Allouch</surname><given-names>S</given-names> </name><name name-style="western"><surname>Brusse-Keizer</surname><given-names>M</given-names> </name><name name-style="western"><surname>Postel</surname><given-names>MG</given-names> </name><name name-style="western"><surname>Pieterse</surname><given-names>ME</given-names> </name></person-group><article-title>Identification of users for a smoking cessation mobile app: quantitative study</article-title><source>J Med Internet Res</source><year>2018</year><volume>20</volume><issue>4</issue><fpage>e118</fpage><pub-id pub-id-type="doi">10.2196/jmir.7606</pub-id></nlm-citation></ref><ref id="ref58"><label>58</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Kostagiolas</surname><given-names>P</given-names> </name><name name-style="western"><surname>Parnavela</surname><given-names>S</given-names> </name><name name-style="western"><surname>Theodorou</surname><given-names>P</given-names> </name></person-group><article-title>The impact of smokers' information-seeking behavior on smoking cessation</article-title><source>Adv Exp Med Biol</source><year>2023</year><volume>1425</volume><fpage>645</fpage><lpage>662</lpage><pub-id pub-id-type="doi">10.1007/978-3-031-31986-0_63</pub-id><pub-id pub-id-type="medline">37581838</pub-id></nlm-citation></ref><ref id="ref59"><label>59</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Gravely</surname><given-names>S</given-names> </name><name name-style="western"><surname>Cummings</surname><given-names>KM</given-names> </name><name name-style="western"><surname>Hammond</surname><given-names>D</given-names> </name><etal/></person-group><article-title>Self-reported quit aids and assistance used by smokers at their most recent quit attempt: findings from the 2020 International Tobacco Control Four Country Smoking and Vaping Survey</article-title><source>Nicotine Tob Res</source><year>2021</year><month>08</month><day>29</day><volume>23</volume><issue>10</issue><fpage>1699</fpage><lpage>1707</lpage><pub-id pub-id-type="doi">10.1093/ntr/ntab068</pub-id><pub-id pub-id-type="medline">33837435</pub-id></nlm-citation></ref><ref id="ref60"><label>60</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Coups</surname><given-names>EJ</given-names> </name><name name-style="western"><surname>Dhingra</surname><given-names>LK</given-names> </name><name name-style="western"><surname>Heckman</surname><given-names>CJ</given-names> </name><name name-style="western"><surname>Manne</surname><given-names>SL</given-names> </name></person-group><article-title>Receipt of provider advice for smoking cessation and use of smoking cessation treatments among cancer survivors</article-title><source>J Gen Intern Med</source><year>2009</year><month>11</month><volume>24 Suppl 2</volume><issue>Suppl 2</issue><fpage>S480</fpage><lpage>6</lpage><pub-id pub-id-type="doi">10.1007/s11606-009-0978-9</pub-id><pub-id pub-id-type="medline">19838854</pub-id></nlm-citation></ref><ref id="ref61"><label>61</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Graham</surname><given-names>AL</given-names> </name><name name-style="western"><surname>Amato</surname><given-names>MS</given-names> </name></person-group><article-title>Twelve million smokers look online for smoking cessation help annually: Health Information National Trends Survey Data, 2005-2017</article-title><source>Nicotine Tob Res</source><year>2019</year><month>01</month><day>4</day><volume>21</volume><issue>2</issue><fpage>249</fpage><lpage>252</lpage><pub-id pub-id-type="doi">10.1093/ntr/nty043</pub-id><pub-id pub-id-type="medline">29660037</pub-id></nlm-citation></ref><ref id="ref62"><label>62</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Beard</surname><given-names>E</given-names> </name><name name-style="western"><surname>Brown</surname><given-names>J</given-names> </name><name name-style="western"><surname>Michie</surname><given-names>S</given-names> </name><name name-style="western"><surname>Kaner</surname><given-names>E</given-names> </name><name name-style="western"><surname>Meier</surname><given-names>P</given-names> </name><name name-style="western"><surname>West</surname><given-names>R</given-names> </name></person-group><article-title>Use of aids for smoking cessation and alcohol reduction: a population survey of adults in England</article-title><source>BMC Public Health</source><year>2016</year><month>12</month><day>8</day><volume>16</volume><issue>1</issue><fpage>1237</fpage><pub-id pub-id-type="doi">10.1186/s12889-016-3862-7</pub-id><pub-id pub-id-type="medline">27931202</pub-id></nlm-citation></ref><ref id="ref63"><label>63</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Perski</surname><given-names>O</given-names> </name><name name-style="western"><surname>Jackson</surname><given-names>SE</given-names> </name><name name-style="western"><surname>Garnett</surname><given-names>C</given-names> </name><name name-style="western"><surname>West</surname><given-names>R</given-names> </name><name name-style="western"><surname>Brown</surname><given-names>J</given-names> </name></person-group><article-title>Trends in and factors associated with the adoption of digital aids for smoking cessation and alcohol reduction: a population survey in England</article-title><source>Drug Alcohol Depend</source><year>2019</year><month>12</month><day>1</day><volume>205</volume><fpage>107653</fpage><pub-id pub-id-type="doi">10.1016/j.drugalcdep.2019.107653</pub-id><pub-id pub-id-type="medline">31675544</pub-id></nlm-citation></ref><ref id="ref64"><label>64</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Mojtabai</surname><given-names>R</given-names> </name><name name-style="western"><surname>Riehm</surname><given-names>KE</given-names> </name><name name-style="western"><surname>Cohen</surname><given-names>JE</given-names> </name><name name-style="western"><surname>Alexander</surname><given-names>GC</given-names> </name><name name-style="western"><surname>Vernick</surname><given-names>JS</given-names> </name><name name-style="western"><surname>Thrul</surname><given-names>J</given-names> </name></person-group><article-title>Cigarette excise taxes, clean indoor air laws, and use of smoking cessation treatments: a mediation analysis</article-title><source>Prev Med</source><year>2020</year><month>07</month><volume>136</volume><fpage>106098</fpage><pub-id pub-id-type="doi">10.1016/j.ypmed.2020.106098</pub-id><pub-id pub-id-type="medline">32333928</pub-id></nlm-citation></ref><ref id="ref65"><label>65</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Soulakova</surname><given-names>JN</given-names> </name><name name-style="western"><surname>Crockett</surname><given-names>LJ</given-names> </name></person-group><article-title>Unassisted quitting and smoking cessation methods used in the United States: analyses of 2010-2011 Tobacco Use Supplement to the Current Population Survey Data</article-title><source>Nicotine Tob Res</source><year>2017</year><month>12</month><day>13</day><volume>20</volume><issue>1</issue><fpage>30</fpage><lpage>39</lpage><pub-id pub-id-type="doi">10.1093/ntr/ntw273</pub-id><pub-id pub-id-type="medline">27798084</pub-id></nlm-citation></ref><ref id="ref66"><label>66</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Dai</surname><given-names>HD</given-names> </name><name name-style="western"><surname>Hanh</surname><given-names>P</given-names> </name><name name-style="western"><surname>Guenzel</surname><given-names>N</given-names> </name><name name-style="western"><surname>Morgan</surname><given-names>M</given-names> </name><name name-style="western"><surname>Kerns</surname><given-names>E</given-names> </name><name name-style="western"><surname>Winickoff</surname><given-names>JP</given-names> </name></person-group><article-title>Adoption of vaping cessation methods by US adolescent e-cigarette users</article-title><source>Pediatrics</source><year>2023</year><month>11</month><day>1</day><volume>152</volume><issue>5</issue><fpage>e2023062948</fpage><pub-id pub-id-type="doi">10.1542/peds.2023-062948</pub-id><pub-id pub-id-type="medline">37781732</pub-id></nlm-citation></ref><ref id="ref67"><label>67</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Jones</surname><given-names>E</given-names> </name><name name-style="western"><surname>Endrighi</surname><given-names>R</given-names> </name><name name-style="western"><surname>Weinstein</surname><given-names>D</given-names> </name><name name-style="western"><surname>Jankowski</surname><given-names>A</given-names> </name><name name-style="western"><surname>Quintiliani</surname><given-names>LM</given-names> </name><name name-style="western"><surname>Borrelli</surname><given-names>B</given-names> </name></person-group><article-title>Methods used to quit vaping among adolescents and associations with perceived risk, addiction, and socio-economic status</article-title><source>Addict Behav</source><year>2023</year><month>12</month><volume>147</volume><fpage>107835</fpage><pub-id pub-id-type="doi">10.1016/j.addbeh.2023.107835</pub-id><pub-id pub-id-type="medline">37598643</pub-id></nlm-citation></ref><ref id="ref68"><label>68</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Mattingly</surname><given-names>DT</given-names> </name><name name-style="western"><surname>Hart</surname><given-names>JL</given-names> </name></person-group><article-title>Trends in current electronic cigarette use among youths by age, sex, and race and ethnicity</article-title><source>JAMA Netw Open</source><year>2024</year><month>02</month><day>5</day><volume>7</volume><issue>2</issue><fpage>e2354872</fpage><pub-id pub-id-type="doi">10.1001/jamanetworkopen.2023.54872</pub-id><pub-id pub-id-type="medline">38315486</pub-id></nlm-citation></ref><ref id="ref69"><label>69</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Kalgotra</surname><given-names>P</given-names> </name><name name-style="western"><surname>Raja</surname><given-names>U</given-names> </name><name name-style="western"><surname>Sharda</surname><given-names>R</given-names> </name></person-group><article-title>Growth in the development of health and fitness mobile apps amid COVID-19 pandemic</article-title><source>Digit Health</source><year>2022</year><volume>8</volume><fpage>20552076221129070</fpage><pub-id pub-id-type="doi">10.1177/20552076221129070</pub-id><pub-id pub-id-type="medline">36211794</pub-id></nlm-citation></ref><ref id="ref70"><label>70</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Cobos-Campos</surname><given-names>R</given-names> </name><name name-style="western"><surname>Cordero-Guevara</surname><given-names>JA</given-names> </name><name name-style="western"><surname>Api&#x00F1;aniz</surname><given-names>A</given-names> </name><etal/></person-group><article-title>The impact of digital health on smoking cessation</article-title><source>Interact J Med Res</source><year>2023</year><month>03</month><day>15</day><volume>12</volume><fpage>e41182</fpage><pub-id pub-id-type="doi">10.2196/41182</pub-id><pub-id pub-id-type="medline">36920468</pub-id></nlm-citation></ref><ref id="ref71"><label>71</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Haskins</surname><given-names>BL</given-names> </name><name name-style="western"><surname>Lesperance</surname><given-names>D</given-names> </name><name name-style="western"><surname>Gibbons</surname><given-names>P</given-names> </name><name name-style="western"><surname>Boudreaux</surname><given-names>ED</given-names> </name></person-group><article-title>A systematic review of smartphone applications for smoking cessation</article-title><source>Transl Behav Med</source><year>2017</year><month>06</month><volume>7</volume><issue>2</issue><fpage>292</fpage><lpage>299</lpage><pub-id pub-id-type="doi">10.1007/s13142-017-0492-2</pub-id><pub-id pub-id-type="medline">28527027</pub-id></nlm-citation></ref><ref id="ref72"><label>72</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Bold</surname><given-names>KW</given-names> </name><name name-style="western"><surname>Garrison</surname><given-names>KA</given-names> </name><name name-style="western"><surname>DeLucia</surname><given-names>A</given-names> </name><etal/></person-group><article-title>Smartphone apps for smoking cessation: systematic framework for app review and analysis</article-title><source>J Med Internet Res</source><year>2023</year><month>07</month><day>13</day><volume>25</volume><fpage>e45183</fpage><pub-id pub-id-type="doi">10.2196/45183</pub-id><pub-id pub-id-type="medline">37440305</pub-id></nlm-citation></ref><ref id="ref73"><label>73</label><nlm-citation citation-type="web"><article-title>Digital 2024: 5 billion social media users</article-title><source>We Are Social</source><access-date>2026-03-06</access-date><comment><ext-link ext-link-type="uri" xlink:href="https://wearesocial.com/uk/blog/2024/01/digital-2024-5-billion-social-media-users/">https://wearesocial.com/uk/blog/2024/01/digital-2024-5-billion-social-media-users/</ext-link></comment></nlm-citation></ref><ref id="ref74"><label>74</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Luo</surname><given-names>T</given-names> </name><name name-style="western"><surname>Li</surname><given-names>MS</given-names> </name><name name-style="western"><surname>Williams</surname><given-names>D</given-names> </name><etal/></person-group><article-title>Using social media for smoking cessation interventions: a systematic review</article-title><source>Perspect Public Health</source><year>2021</year><month>01</month><volume>141</volume><issue>1</issue><fpage>50</fpage><lpage>63</lpage><pub-id pub-id-type="doi">10.1177/1757913920906845</pub-id></nlm-citation></ref><ref id="ref75"><label>75</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Naslund</surname><given-names>JA</given-names> </name><name name-style="western"><surname>Kim</surname><given-names>SJ</given-names> </name><name name-style="western"><surname>Aschbrenner</surname><given-names>KA</given-names> </name><etal/></person-group><article-title>Systematic review of social media interventions for smoking cessation</article-title><source>Addict Behav</source><year>2017</year><month>10</month><volume>73</volume><fpage>81</fpage><lpage>93</lpage><pub-id pub-id-type="doi">10.1016/j.addbeh.2017.05.002</pub-id><pub-id pub-id-type="medline">28499259</pub-id></nlm-citation></ref><ref id="ref76"><label>76</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Gliwska</surname><given-names>E</given-names> </name><name name-style="western"><surname>Ma&#x0144;czuk</surname><given-names>M</given-names> </name></person-group><article-title>Digital interventions in smoking cessation &#x2013; a brief overview of systematic reviews and meta-analyses</article-title><source>Nowotwory</source><year>2024</year><volume>74</volume><issue>1</issue><fpage>66</fpage><lpage>71</lpage><pub-id pub-id-type="doi">10.5603/njo.98341</pub-id></nlm-citation></ref><ref id="ref77"><label>77</label><nlm-citation citation-type="web"><article-title>Young people - digital world</article-title><source>Eurostat</source><access-date>2026-03-06</access-date><comment><ext-link ext-link-type="uri" xlink:href="https://ec.europa.eu/eurostat/statistics-explained/index.php?title=Young_people_-_digital_world">https://ec.europa.eu/eurostat/statistics-explained/index.php?title=Young_people_-_digital_world</ext-link></comment></nlm-citation></ref><ref id="ref78"><label>78</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Papp-Zipernovszky</surname><given-names>O</given-names> </name><name name-style="western"><surname>Horv&#x00E1;th</surname><given-names>MD</given-names> </name><name name-style="western"><surname>Schulz</surname><given-names>PJ</given-names> </name><name name-style="western"><surname>Csabai</surname><given-names>M</given-names> </name></person-group><article-title>Generation gaps in digital health literacy and their impact on health information seeking behavior and health empowerment in Hungary</article-title><source>Front Public Health</source><year>2021</year><volume>9</volume><issue>May</issue><fpage>635943</fpage><pub-id pub-id-type="doi">10.3389/fpubh.2021.635943</pub-id><pub-id pub-id-type="medline">34055714</pub-id></nlm-citation></ref><ref id="ref79"><label>79</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Hsu</surname><given-names>WC</given-names> </name></person-group><article-title>The effect of age on electronic health literacy: mixed-method study</article-title><source>JMIR Hum Factors</source><year>2019</year><month>04</month><day>21</day><volume>6</volume><issue>2</issue><fpage>e11480</fpage><pub-id pub-id-type="doi">10.2196/11480</pub-id><pub-id pub-id-type="medline">31066696</pub-id></nlm-citation></ref><ref id="ref80"><label>80</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Dratva</surname><given-names>J</given-names> </name><name name-style="western"><surname>Schaeffer</surname><given-names>D</given-names> </name><name name-style="western"><surname>Zeeb</surname><given-names>H</given-names> </name></person-group><article-title>Digital health literacy in Germany: current status, concepts, and challenges</article-title><source>Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz</source><year>2024</year><month>03</month><volume>67</volume><issue>3</issue><fpage>277</fpage><lpage>284</lpage><pub-id pub-id-type="doi">10.1007/s00103-024-03841-5</pub-id><pub-id pub-id-type="medline">38315221</pub-id></nlm-citation></ref><ref id="ref81"><label>81</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Estrela</surname><given-names>M</given-names> </name><name name-style="western"><surname>Semedo</surname><given-names>G</given-names> </name><name name-style="western"><surname>Roque</surname><given-names>F</given-names> </name><name name-style="western"><surname>Ferreira</surname><given-names>PL</given-names> </name><name name-style="western"><surname>Herdeiro</surname><given-names>MT</given-names> </name></person-group><article-title>Sociodemographic determinants of digital health literacy: a systematic review and meta-analysis</article-title><source>Int J Med Inform</source><year>2023</year><month>09</month><volume>177</volume><issue>May</issue><fpage>105124</fpage><pub-id pub-id-type="doi">10.1016/j.ijmedinf.2023.105124</pub-id><pub-id pub-id-type="medline">37329766</pub-id></nlm-citation></ref></ref-list><app-group><supplementary-material id="app1"><label>Multimedia Appendix 1</label><p>Search strategy, JBI Critical Appraisal Checklist, excluded articles with reason of exclusion, studies definition of smokers, and results stratified by sex/age.</p><media xlink:href="jmir_v28i1e83072_app1.docx" xlink:title="DOCX File, 53 KB"/></supplementary-material><supplementary-material id="app2"><label>Checklist 1</label><p>PRISMA-S checklist.</p><media xlink:href="jmir_v28i1e83072_app2.pdf" xlink:title="PDF File, 121 KB"/></supplementary-material></app-group></back></article>