<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article PUBLIC "-//NLM//DTD Journal Publishing DTD v2.0 20040830//EN" "journalpublishing.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" dtd-version="2.0" xml:lang="en" article-type="news"><front><journal-meta><journal-id journal-id-type="nlm-ta">J Med Internet Res</journal-id><journal-id journal-id-type="publisher-id">jmir</journal-id><journal-id journal-id-type="index">1</journal-id><journal-title>Journal of Medical Internet Research</journal-title><abbrev-journal-title>J Med Internet Res</abbrev-journal-title><issn pub-type="epub">1438-8871</issn><publisher><publisher-name>JMIR Publications</publisher-name><publisher-loc>Toronto, Canada</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">v28i1e106580</article-id><article-id pub-id-type="doi">10.2196/106580</article-id><article-categories><subj-group subj-group-type="heading"><subject>News and Perspectives</subject></subj-group></article-categories><title-group><article-title>From Spatial AI to Clinical Readiness: Lessons From Augmented World Expo USA 2026</article-title></title-group><contrib-group><contrib contrib-type="author"><name name-style="western"><surname>Costa</surname><given-names>Jose Ferrer</given-names></name><role>JMIR Correspondent</role></contrib></contrib-group><contrib-group><contrib contrib-type="editor"><name name-style="western"><surname>Clegg</surname><given-names>Kayleigh-Ann</given-names></name></contrib></contrib-group><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>17</day><month>7</month><year>2026</year></pub-date><volume>28</volume><elocation-id>e106580</elocation-id><history><date date-type="received"><day>08</day><month>07</month><year>2026</year></date><date date-type="accepted"><day>08</day><month>07</month><year>2026</year></date></history><copyright-statement>&#x00A9; JMIR Publications. Originally published in the Journal of Medical Internet Research (<ext-link ext-link-type="uri" xlink:href="https://www.jmir.org">https://www.jmir.org</ext-link>), 17.7.2026. </copyright-statement><copyright-year>2026</copyright-year><self-uri xlink:type="simple" xlink:href="https://www.jmir.org/2026/1/e106580"/><abstract><p>Augmented World Expo (AWE) USA 2026 took place from June 15 to 18 in Long Beach, California, and brought together researchers, developers, investors, start-ups, and tech experts from across the extended reality (XR) ecosystem. In this <italic>News and Perspectives</italic> article, JMIR Correspondent Jos&#x00E9; Ferrer Costa reports on the major themes and trends he observed at the conference.</p></abstract><kwd-group><kwd>extended reality</kwd><kwd>XR</kwd><kwd>virtual reality</kwd><kwd>augmented reality</kwd><kwd>spatial computing</kwd><kwd>spatial AI</kwd><kwd>digital health</kwd><kwd>implementation science</kwd><kwd>clinical adoption</kwd><kwd>health care innovation</kwd></kwd-group></article-meta></front><body><boxed-text id="box1"><p><bold>Key Takeaways:</bold></p><list list-type="bullet"><list-item><p>Augmented World Expo (AWE) USA 2026 suggested that extended reality (XR) is not simply returning after the AI hype cycle but being reassembled around spatial AI, smart glasses, wearable computing, and enterprise infrastructure.</p></list-item><list-item><p>The main clinical question that emerged was whether health systems can turn promising XR demos into reliable care processes, with the staffing, hygiene routines, workflow fit, reimbursement pathways, governance, and accountability needed to move beyond the pilot stage.</p></list-item></list></boxed-text><p><italic>Jos&#x00E9; Ferrer Costa is a family physician, clinical researcher, and extended reality (XR) implementation lead at Badalona Serveis Assistencials in Barcelona. His work focuses on bringing immersive technologies into real clinical settings, while his PhD research at the Universitat Oberta de Catalunya examines how health systems can decide when XR is ready for adoption. Note: he has invested in Biel Glasses but has no financial or commercial relationships with Augmented World Expo (AWE) or any of the products reported here.</italic></p><p><ext-link ext-link-type="uri" xlink:href="https://www.awexr.com/usa-2026/">AWE USA 2026</ext-link> opened with a clear theme: &#x201C;I, Spatial: Humans Empowered by Spatial AI.&#x201D; More than 5000 attendees, 250 exhibitors, and 400 speakers gathered around a field that now feels less centered on headsets than on spatial infrastructure. For health care, this was the most relevant signal. XR is not only gaining momentum again; it is becoming part of a wider ecosystem of spatial AI, smart glasses, wearable computing, robotics, digital twins, and enterprise platforms.</p><p>After years of pilots in <ext-link ext-link-type="uri" xlink:href="https://journals.sagepub.com/doi/full/10.1089/jmxr.2023.0012">education, rehabilitation, pain care, mental health and procedural support</ext-link>, the central issue in clinical XR is no longer whether immersive technologies can produce meaningful clinical experiences but whether health care organizations can <ext-link ext-link-type="uri" xlink:href="https://link.springer.com/article/10.1186/s43058-023-00442-2">implement them</ext-link> safely, reliably, and sustainably.</p><sec id="s1"><title>From Headsets to Spatial Infrastructure</title><p>The shift was visible in the attention given to smart glasses, on-device AI, hand tracking, and cross-device development. Together, these pointed toward lighter, more flexible, and more context-aware systems.</p><p>Several <ext-link ext-link-type="uri" xlink:href="https://www.awexr.com/blog/awe-usa-2026-major-product-launches-new-immersive-experiences-and-industry-announcements">examples from the expo floor</ext-link> made this change concrete. <ext-link ext-link-type="uri" xlink:href="https://www.xreal.com/aura">XREAL AURA</ext-link>, formerly Project Aura, pointed toward lightweight, optical, see-through glasses built around Android XR, Gemini integration, and split-compute architecture. <ext-link ext-link-type="uri" xlink:href="https://mentraglass.com/">MentraOS</ext-link> suggested another part of the emerging infrastructure: an open-source platform for deploying applications across different smart glasses brands in real-world workflows. Avalon Holographics&#x2019; <ext-link ext-link-type="uri" xlink:href="https://avalonholographics.com/product/">NOVAC</ext-link> offered a different angle, showing how shared, glasses-free, 3D holograms could allow teams to work around the same spatial content without requiring everyone in the room to wear a headset. In medicine, that matters for collaborative settings, such as tumor boards, where professionals with different roles and levels of technical comfort need to reason around the same anatomy or planning problem.</p><p>These details are not cosmetic. A device that fits better in a rehabilitation room, training space, or procedural environment is more implementable. Hand tracking may reduce controller-related friction, while on-device AI could support faster and more privacy-sensitive workflows. Smart glasses could eventually document laboratory procedures, surgical workflows, or training encounters from the clinician&#x2019;s point of view, thereby supporting teaching and documentation and turning clinical action into data.</p><p>Hospitals are no longer evaluating only an app and a headset. They are evaluating an ecosystem, making clinical readiness harder to define.</p></sec><sec id="s2"><title>Health Care Was No Longer Peripheral</title><p>Health care had a structured presence across the <ext-link ext-link-type="uri" xlink:href="https://www.awexr.com/usa-2026/agenda?track=Healthcare%20%26%20Wellness">program</ext-link>, expo floor, professional association spaces, and enterprise discussions. The <ext-link ext-link-type="uri" xlink:href="https://ivrha.org/">International Virtual Reality Healthcare Association</ext-link><ext-link ext-link-type="uri" xlink:href="https://ivrha.org/"> (IVRHA</ext-link><ext-link ext-link-type="uri" xlink:href="https://ivrha.org/">)</ext-link> area gave clinical XR a practical meeting point, bringing together the American Medical Extended Reality Association (AMXRA) and several health-focused XR companies. The newly introduced <ext-link ext-link-type="uri" xlink:href="https://www.awexr.com/blog/awe-research-poster-track">Research Poster Track</ext-link> presented 15 posters from 40 submissions, reporting health care as the largest category. Together, these elements reinforced a broader shift: medical XR is developing its own professional networks, evidence standards, and implementation agenda.</p><p>This visibility created constructive pressure. Clinical XR was being discussed beside enterprise infrastructure, AI wearables, smart glasses, start-up pitches, research presentations, and implementation roundtables. That proximity made the field feel less like a niche application area and more like a test case for whether spatial computing can survive contact with real clinical constraints.</p><p>A few <ext-link ext-link-type="uri" xlink:href="https://www.awexr.com/blog/1382-2026-auggie-awards-finalists-announced">awarded</ext-link> product examples made this shift tangible. <ext-link ext-link-type="uri" xlink:href="https://bielglasses.com/">Biel Glasses</ext-link> represented assistive XR for low vision and daily autonomy, <ext-link ext-link-type="uri" xlink:href="https://enovis.com/products/surgical/arvisr">ARVIS</ext-link> pointed toward augmented reality surgical navigation, and <ext-link ext-link-type="uri" xlink:href="https://www.immergolabs.com/">Immergo Labs</ext-link> and <ext-link ext-link-type="uri" xlink:href="https://www.avrwell.com/">AVRwell</ext-link> reflected the growing role of XR in rehabilitation and movement care. No single product defined the field; clinical XR is diversifying into use cases with very different requirements for safety, validation, workflow integration, and long-term support.</p><p>A good prototype can show that an immersive experience is technically possible. It does not show whether a hospital can maintain it, clean it, update it, evaluate it, reimburse it, or place it safely inside a patient pathway. The presence of health care across AWE mattered because it exposed clinical XR to those harder questions earlier.</p></sec><sec id="s3"><title>The Implementation Test</title><p>The most useful lesson from AWE was simple and slightly inconvenient: a good XR demo is not the same as a clinical service.</p><p>Across roundtables, enterprise sessions, and informal conversations, the same issue kept resurfacing: what makes an XR pilot survive after the first enthusiastic demonstration?</p><p>In health care, this becomes very concrete. Who prepares the headset? Who cleans it? Who resets the software? Who supports the clinician? Who explains the experience to the patient? And, perhaps most importantly, who is responsible when the technology becomes part of care?</p><p>In our Healthcare - Scaling and Solutions <ext-link ext-link-type="uri" xlink:href="https://www.awexr.com/usa-2026/agenda/1946">roundtable</ext-link>, the discussion quickly moved from clinical promise to operational reality. Participants moved from abstract enthusiasm to practical barriers, shared responsibilities, and the everyday work needed to make immersive tools usable in care.</p><p>Enterprise sessions echoed the same logic from a different angle: XR programs need internal champions, well-chosen use cases, measurable value, device and content management, staff adoption, and enough flexibility to avoid early dependence on a single platform.</p><fig position="float" id="figureWL1"><graphic alt-version="no" mimetype="image" position="float" xlink:type="simple" xlink:href="jmir_v28i1e106580_fig01.png"/></fig><p>In industry, this is often framed as return on investment and scalability. In health care, the translation is more demanding: clinical value, safety, staff time, patient experience, reimbursement, and governance. Clinical XR should not be treated as a headset purchase or a content library. It behaves more like a service layer, requiring people, protocols, maintenance, infection-control routines, technical support, and a clear place in the patient pathway.</p><p>AWE highlighted that the future of clinical XR will not be decided only by the most impressive devices. It will be decided by the health systems that can turn immersive experiences into reliable clinical processes.</p><fig position="float" id="figureWL2"><caption><p><italic>Healthcare - Scaling and Solutions roundtable at Augmented World Expo (AWE) USA 2026</italic>. <italic>Credit: Jos&#x00E9; Ferrer Costa.</italic></p></caption><graphic alt-version="no" mimetype="image" position="float" xlink:type="simple" xlink:href="jmir_v28i1e106580_fig02.png"/></fig></sec><sec id="s4"><title>The Future of Clinical XR</title><p>Health care remains one of the most credible domains for XR because medicine is already spatial, embodied, and procedural. Clinicians learn anatomy in three dimensions; rehearse procedures through movement; interpret spatial relationships in imaging; and support rehabilitation, exposure-based care, attention training, and behavior change. XR does not need AI to justify its relevance in health care, although spatial AI may change what clinical XR can become.</p><p>That may be the real lesson from AWE USA 2026. Clinical XR is not waiting only for its next technical breakthrough. It is waiting for health systems capable of deciding, responsibly and realistically, when immersive experiences belong in care and when they do not. In health care, responsible implementation is not the slow administrative phase after innovation. It is what makes innovation clinically meaningful. The future rarely arrives as a keynote. More often, it arrives as a workflow.</p></sec></body><back/></article>