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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JMIR</journal-id>
      <journal-id journal-id-type="nlm-ta">J Med Internet Res</journal-id>
      <journal-title>Journal of Medical Internet Research</journal-title>
      <issn pub-type="epub">1438-8871</issn>
      <publisher>
        <publisher-name>JMIR Publications</publisher-name>
        <publisher-loc>Toronto, Canada</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">v27i1e66324</article-id>
      <article-id pub-id-type="pmid">40526914</article-id>
      <article-id pub-id-type="doi">10.2196/66324</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Review</subject>
        </subj-group>
        <subj-group subj-group-type="article-type">
          <subject>Review</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Ecological Momentary Assessment to Measure Social Connectedness in Older Adults: Integrative Review</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="editor">
          <name>
            <surname>Cahill</surname>
            <given-names>Naomi</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Chang</surname>
            <given-names>Soo Jung</given-names>
          </name>
        </contrib>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Chau</surname>
            <given-names>Anson Kai Chun</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib id="contrib1" contrib-type="author">
          <name name-style="western">
            <surname>Choi</surname>
            <given-names>Seongmi</given-names>
          </name>
          <degrees>PhD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <xref rid="aff2" ref-type="aff">2</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-0988-9307</ext-link>
        </contrib>
        <contrib id="contrib2" contrib-type="author">
          <name name-style="western">
            <surname>Kang</surname>
            <given-names>Hun</given-names>
          </name>
          <degrees>MPH</degrees>
          <xref rid="aff3" ref-type="aff">3</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-5312-1493</ext-link>
        </contrib>
        <contrib id="contrib3" contrib-type="author">
          <name name-style="western">
            <surname>Shin</surname>
            <given-names>Jiyoung</given-names>
          </name>
          <degrees>PhD</degrees>
          <xref rid="aff2" ref-type="aff">2</xref>
          <xref rid="aff4" ref-type="aff">4</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0009-0003-6279-1047</ext-link>
        </contrib>
        <contrib id="contrib4" contrib-type="author">
          <name name-style="western">
            <surname>Chu</surname>
            <given-names>Sang Hui</given-names>
          </name>
          <degrees>PhD</degrees>
          <xref rid="aff2" ref-type="aff">2</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0001-6877-5599</ext-link>
        </contrib>
        <contrib id="contrib5" contrib-type="author" corresp="yes">
          <name name-style="western">
            <surname>Choi</surname>
            <given-names>JiYeon</given-names>
          </name>
          <degrees>PhD</degrees>
          <xref rid="aff2" ref-type="aff">2</xref>
          <address>
            <institution/>
            <institution>Mo-Im Kim Nursing Research Institute, Yonsei University College of Nursing</institution>
            <addr-line>50 Yonsei-ro, Seodaemun-gu</addr-line>
            <addr-line>Seoul, 03722</addr-line>
            <country>Republic of Korea</country>
            <phone>82 2 2228 3301</phone>
            <email>jychoi610@yuhs.ac</email>
          </address>
          <xref rid="aff5" ref-type="aff">5</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0003-1947-7952</ext-link>
        </contrib>
      </contrib-group>
      <aff id="aff1">
        <label>1</label>
        <institution>Research Institute of Nursing Science, Daegu Catholic University College of Nursing</institution>
        <addr-line>Daegu</addr-line>
        <country>Republic of Korea</country>
      </aff>
      <aff id="aff2">
        <label>2</label>
        <institution>Mo-Im Kim Nursing Research Institute, Yonsei University College of Nursing</institution>
        <addr-line>Seoul</addr-line>
        <country>Republic of Korea</country>
      </aff>
      <aff id="aff3">
        <label>3</label>
        <institution>Yonsei University College of Nursing</institution>
        <addr-line>Seoul</addr-line>
        <country>Republic of Korea</country>
      </aff>
      <aff id="aff4">
        <label>4</label>
        <institution>Health Insurance Research Institute, National Health Insurance Service</institution>
        <addr-line>Gangwon-Do</addr-line>
        <country>Republic of Korea</country>
      </aff>
      <aff id="aff5">
        <label>5</label>
        <institution>Institute for Innovation in Digital Healthcare, Yonsei University</institution>
        <addr-line>Seoul</addr-line>
        <country>Republic of Korea</country>
      </aff>
      <author-notes>
        <corresp>Corresponding Author: JiYeon Choi <email>jychoi610@yuhs.ac</email></corresp>
      </author-notes>
      <pub-date pub-type="collection">
        <year>2025</year>
      </pub-date>
      <pub-date pub-type="epub">
        <day>17</day>
        <month>6</month>
        <year>2025</year>
      </pub-date>
      <volume>27</volume>
      <elocation-id>e66324</elocation-id>
      <history>
        <date date-type="received">
          <day>10</day>
          <month>9</month>
          <year>2024</year>
        </date>
        <date date-type="rev-request">
          <day>5</day>
          <month>1</month>
          <year>2025</year>
        </date>
        <date date-type="rev-recd">
          <day>30</day>
          <month>3</month>
          <year>2025</year>
        </date>
        <date date-type="accepted">
          <day>21</day>
          <month>4</month>
          <year>2025</year>
        </date>
      </history>
      <copyright-statement>©Seongmi Choi, Hun Kang, Jiyoung Shin, Sang Hui Chu, JiYeon Choi. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 17.06.2025.</copyright-statement>
      <copyright-year>2025</copyright-year>
      <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
        <p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Journal of Medical Internet Research (ISSN 1438-8871), is properly cited. The complete bibliographic information, a link to the original publication on https://www.jmir.org/, as well as this copyright and license information must be included.</p>
      </license>
      <self-uri xlink:href="https://www.jmir.org/2025/1/e66324" xlink:type="simple"/>
      <abstract>
        <sec sec-type="background">
          <title>Background</title>
          <p>The importance of social connectedness as a determinant of health and well-being in older adults is well-established. Ecological momentary assessment (EMA) shows promise for real-time measurement of social interactions, making it worthwhile to investigate its feasibility and the challenges of applying it to older adults.</p>
        </sec>
        <sec sec-type="objective">
          <title>Objective</title>
          <p>This integrative review aimed to (1) summarize and integrate the implementation of EMA in assessing older adults’ social connectedness, and (2) discuss the EMA method and its use to assess the concept of social connectedness in order to guide future research.</p>
        </sec>
        <sec sec-type="methods">
          <title>Methods</title>
          <p>A total of 5 databases—PubMed, CINAHL, Embase, Web of Science, and PsycINFO—were searched for studies published up to March 2025. We included studies that (1) targeted adults aged 60 years or older, (2) used EMA to assess social connectedness, and (3) were published in a peer-reviewed journal. Studies using third-party reports to obtain EMA data and studies focusing on marital dyads were excluded. The analysis identified multifactorial constructs of social connectedness (structural, functional, and quality) and assessed EMA protocols and compliance or adherence to EMA.</p>
        </sec>
        <sec sec-type="results">
          <title>Results</title>
          <p>Of the 18,886 studies identified, 43 were selected for final analysis. Social connectedness assessed via EMA mostly focused on the structural dimension, capturing whether an individual had social contact at a given moment (38/43, 88%). Among functional dimension (17/43, 40%), loneliness was the most measured construct, and the quality dimension (16/43, 37%) included quality of social interaction, pleasantness of encounters, and interpersonal tensions. In total, 2 studies addressed all 3 dimensions of social connectedness. In addition, to provide context for understanding social connectedness, assessments considered location at the time of assessment, type of activity, and physical (eg, pain and fatigue) and psychological states (eg, positive or negative mood). Data were mostly collected using an app on digital devices (eg, smartphone), and assessments were conducted 1-7 times per day for 5 to 25 days, achieving a compliance rate of over 70%.</p>
        </sec>
        <sec sec-type="conclusions">
          <title>Conclusions</title>
          <p>The findings of this study highlight the current state of science in measuring social connectedness in older adults through EMA and demonstrate its feasibility in real-world settings. Further research is suggested to address the conceptual and methodological challenges of EMA, as measurement of multifactorial constructs of social connectedness and standardization of EMA protocols may increase the likelihood of capturing useful information about older adults’ real-time social connectedness.</p>
        </sec>
        <sec sec-type="Trial Registration">
          <title>Trial Registration</title>
          <p>PROSPERO CRD42024499050; https://www.crd.york.ac.uk/PROSPERO/view/CRD42024499050</p>
        </sec>
      </abstract>
      <kwd-group>
        <kwd>aged</kwd>
        <kwd>social connectedness</kwd>
        <kwd>ecological momentary assessment</kwd>
        <kwd>review</kwd>
        <kwd>mobile phone</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec sec-type="introduction">
      <title>Introduction</title>
      <p>Social connectedness is a complex phenomenon encompassing numerous emotional, physical, and behavioral aspects of human interaction, and it is recognized as an important contributor to individual and population health and well-being [<xref ref-type="bibr" rid="ref1">1</xref>]. In older adults, a lack of social connectedness has been linked to adverse effects on a broad spectrum of health outcomes, such as depression, cardiovascular disease, quality of life, overall health, cognitive function, and mortality [<xref ref-type="bibr" rid="ref2">2</xref>]. Although aging itself does not directly cause a reduction in social connectedness, older adults often face an increased prevalence of loss, changes in functional independence, frailty, declining health status, deteriorating relationship quality, shifts in care needs and living arrangements, changes in employment status, and financial instability. These factors can make maintaining social connections more challenging [<xref ref-type="bibr" rid="ref3">3</xref>-<xref ref-type="bibr" rid="ref6">6</xref>]. As the world’s population is expected to age [<xref ref-type="bibr" rid="ref7">7</xref>], the importance of social connectedness is highlighted regarding its role in optimizing the physical health, psychosocial health, and well-being of older adults.</p>
      <p>Despite the well-acknowledged importance of social connectedness, terms such as social contact, integration, perceived support, and loneliness are often used interchangeably [<xref ref-type="bibr" rid="ref8">8</xref>]. However, these terms do not fully capture the breadth of the concept [<xref ref-type="bibr" rid="ref9">9</xref>]. To address this issue, social connectedness has been conceptualized as an umbrella term that encompasses various dimensions, categorized into structural, functional, and quality dimensions [<xref ref-type="bibr" rid="ref8">8</xref>]. Given that each dimension independently influences health outcomes and that the correlations between them are weak, it is crucial to analyze them separately to understand their distinct pathways to health [<xref ref-type="bibr" rid="ref10">10</xref>].</p>
      <p>Ecological momentary assessment (EMA), or experience sampling method, measures individuals’ daily experiences in real time, minimizing researcher control and collecting data in natural settings. This approach helps capture participants’ momentary, specific daily experiences. EMA typically uses mobile devices (eg, smartphones and digital wristwatches) to prompt participants to answer short, targeted questions multiple times a day over several days or weeks [<xref ref-type="bibr" rid="ref11">11</xref>,<xref ref-type="bibr" rid="ref12">12</xref>]. While retrospective recall has been the primary method for assessing social connectedness, it is prone to bias and errors, particularly for minor events like everyday social interactions [<xref ref-type="bibr" rid="ref11">11</xref>,<xref ref-type="bibr" rid="ref13">13</xref>]. In contrast, EMA minimizes recall bias and provides detailed, real-time insights into social dynamics [<xref ref-type="bibr" rid="ref14">14</xref>,<xref ref-type="bibr" rid="ref15">15</xref>].</p>
      <p>However, the feasibility and usability of assessing social connectedness in older adults using EMA remain underexplored. Previous studies have primarily focused on younger populations, often overlooking the unique challenges that older adults may encounter, particularly in relation to technology use [<xref ref-type="bibr" rid="ref16">16</xref>-<xref ref-type="bibr" rid="ref18">18</xref>]. There are several reviews that highlight the feasibility and application of employing EMA in an aging population [<xref ref-type="bibr" rid="ref13">13</xref>,<xref ref-type="bibr" rid="ref19">19</xref>,<xref ref-type="bibr" rid="ref20">20</xref>]. However, no known study has focused on evaluating EMA as a tool to assess social connectedness. Identifying practical challenges and opportunities associated with EMA in studying social connectedness among older adults will provide valuable methodological insights that can support future research. To address this gap, we conducted an integrative review, a research approach that synthesizes findings from diverse methodologies to provide a comprehensive understanding of the phenomenon of interest [<xref ref-type="bibr" rid="ref21">21</xref>]. Accordingly, this study aimed to (1) summarize and integrate the use of EMA in evaluating social connectedness among older adults, and (2) discuss the concept of social connectedness as assessed by EMA, as well as the EMA methodology, to guide future research.</p>
    </sec>
    <sec sec-type="methods">
      <title>Methods</title>
      <sec>
        <title>Search Design</title>
        <p>This integrative review was based on the methodology proposed by Whittemore and Knafl [<xref ref-type="bibr" rid="ref21">21</xref>]. The protocol for this review was registered with PROSPERO (CRD42024499050). Two deviations from the registered protocol were made. First, we collected more comprehensively relevant studies by including additional search terms related to EMA. Second, we extended the literature search period beyond the planned period to include up-to-date studies. This review was guided by the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) [<xref ref-type="bibr" rid="ref22">22</xref>]. The PRISMA checklist was provided as a <xref ref-type="supplementary-material" rid="app1">Multimedia Appendix 1</xref>.</p>
        <p>This review focused on the following variables of interest: target population (older adults aged 60 years or older), concept (EMA), and context (social connectedness). In this study, EMA was defined as a method of repeatedly measuring experiences, behaviors, and emotions in real time or in close proximity to an individual’s daily environment. EMA has properties of repeated measurements such as prompt type (eg, time-based and event-based), collection period (within or over several days), collection frequency within a day, and data collection tools were set as a comprehensive concept that includes paper-based questionnaires and methods using digital technologies such as smartphones, computers, and wearable devices. Social connectedness is defined as a concept encompassing the structural (eg, social contact), functional (eg, loneliness), and quality dimensions (eg, relationship strain) of an individual’s experience through social relationships [<xref ref-type="bibr" rid="ref8">8</xref>].</p>
      </sec>
      <sec>
        <title>Search Strategies</title>
        <p>We conducted a systematic search to identify relevant studies published from the inception of the databases up to March 2025. This study included 5 electronic databases—PubMed, CINAHL, Embase, Web of Science, and PsycINFO. The search terms were developed using a combination of MeSH (Medical Subject Headings) terms and keywords, with the assistance of a professional medical librarian. We have summarized the combination of search terms used for each database in <xref ref-type="supplementary-material" rid="app2">Multimedia Appendix 2</xref>.</p>
      </sec>
      <sec>
        <title>Eligibility Criteria</title>
        <p>The inclusion criteria for the studies were (1) the participants were adults aged 60 years or older, (2) the studies used EMA to evaluate social connectedness, and (3) the studies were published in English. The exclusion criteria included (1) case reports, reviews, editorials, descriptive commentary, conference abstracts, unpublished master’s theses, and doctoral dissertations; (2) studies not specifically targeting older adults; (3) studies that relied on third-party reports to collect EMA data; and (4) studies focusing exclusively on marital dyads. Studies that rely on third-party reports to collect real-time data in clinical settings (eg, patients with dementia residing in long-term care facilities) introduce subjectivity and are limited in their ability to reflect real-world scenarios, as not all situations can be directly observed. Furthermore, although marital dyads can significantly influence the social connectedness of older adults [<xref ref-type="bibr" rid="ref23">23</xref>,<xref ref-type="bibr" rid="ref24">24</xref>], they were excluded from this review due to their focus on a specific type of social relationship.</p>
      </sec>
      <sec>
        <title>Study Screening and Selection</title>
        <p>For screening and selection, all studies were imported into Microsoft Excel. Duplicate records were identified and manually removed within Excel based on matching titles, authors, and publication years. Two authors (SC and HK) independently screened the titles and abstracts of all studies using predefined eligibility criteria. After excluding irrelevant studies, each author independently reviewed the full texts of the remaining studies. At each stage, following the independent screening process, the authors discussed any discrepancies and reached a consensus on the eligibility of each study. These authors had an agreement on the final selection of the studies.</p>
      </sec>
      <sec>
        <title>Quality Evaluation of the Selected Studies</title>
        <p>Two authors, SC and HK, independently assessed the quality of the selected studies using the 2018 version of the Mixed-Methods Appraisal Tool (MMAT) [<xref ref-type="bibr" rid="ref25">25</xref>]. The MMAT is designed to evaluate various study designs, including quantitative, qualitative, and mixed methods, using distinct quality criteria for each type. The tool is divided into 2 parts; part 1, which applies uniform screening criteria across all study designs, and part 2, which uses criteria specific to each design. The items used in part 2 include the following: (1) Are the participants representative of the target population? (2) Are measurements appropriate regarding both the outcome and intervention (or exposure)? (3) Are there complete outcome data? (4) Are the confounders accounted for in the design and analysis? (5) During the study period, is the intervention administered (or exposure occurred) as intended? Responses in part 2 are categorized as “yes,” “no,” or “cannot tell.” We reported the overall quality scores with asterisks, ranging from “none” (none of the quality criteria were met) to “*****” (all 5 criteria were met) [<xref ref-type="bibr" rid="ref25">25</xref>].</p>
      </sec>
      <sec>
        <title>Data Extraction and Synthesis</title>
        <p>Data were extracted using a standardized Microsoft Excel form. Two authors (SC and HK) extracted the selected data into an analysis table. These authors validated and confirmed the analyzed data between articles and table entries for accuracy. Data extracted from studies selected for final review included study characteristics such as author, year of publication, region where the study was conducted, study purpose, sample (size and age), data source, main findings, and factors associated with social connectedness. In addition, EMA protocol details and adherence or compliance rates were reviewed and extracted for each study. Methodological elements—such as prompt design, definition of moment, sampling frequency, device type, training, response strategies, and criteria for valid responses—were extracted. Each study was categorized by data source and compared by identifying the EMA protocol and adherence or compliance rate. To avoid overinterpretation, the findings were synthesized at the data source level.</p>
        <p>To determine the comprehensiveness of social connectedness assessed using EMA in the selected studies, we used the framework by Holt-Lunstad et al [<xref ref-type="bibr" rid="ref8">8</xref>] that depicted indicators of social connectedness with 3 dimensions, that is, structure, function, and quality. The structural dimension is generally quantitative, evaluating the number or diversity of social relationships, or the frequency of social contact (eg, social network and social contact). The functional dimension assesses the actual or perceived availability of support and resources that relationships can provide (eg, perceived social support and perceived loneliness). The quality dimension reflects perceptions of the positive and negative aspects of social relationships (eg, relationship strain and marital quality) [<xref ref-type="bibr" rid="ref8">8</xref>]. Each dimension was divided into trait-level assessment and EMA, with the EMA further categorized according to the definition of moment.</p>
      </sec>
    </sec>
    <sec sec-type="results">
      <title>Results</title>
      <sec>
        <title>Characteristics of the Included Studies</title>
        <p><xref rid="figure1" ref-type="fig">Figure 1</xref> presents a summary of the literature search and selection process using the PRISMA flow diagram. Initially, 18,886 studies were identified across 5 databases; 2447 from PubMed, 529 from CINAHL, 12,162 from Embase, 2253 from Web of Science, and 1495 from PsycINFO. After eliminating 3015 duplicates, we screened the titles and abstracts of 15,871 studies. Subsequently, 97 studies underwent a full-text review. The final sample included 43 studies based on 15 distinct datasets.</p>
        <p><xref ref-type="supplementary-material" rid="app3">Multimedia Appendix 3</xref> provides a summary of the characteristics of the included studies, which were published between 2001 and 2024. Most studies were conducted in the United States (34/43, 79%), with 7 studies from Switzerland (7/43, 16%), 1 each from Australia (1/43, 2%), Canada, and Hong Kong (1/43, 2%). All studies were quantitative in nature and designed with a prospective approach. Most studies used data from large-scale projects such as the Daily Experiences and Well-being Study [<xref ref-type="bibr" rid="ref26">26</xref>-<xref ref-type="bibr" rid="ref40">40</xref>], the Einstein Aging Study [<xref ref-type="bibr" rid="ref15">15</xref>,<xref ref-type="bibr" rid="ref41">41</xref>-<xref ref-type="bibr" rid="ref47">47</xref>], the Chicago Health and Activity Space in Real-Time (CHART) study [<xref ref-type="bibr" rid="ref48">48</xref>-<xref ref-type="bibr" rid="ref51">51</xref>], and the study on digitalization and social lives of older adults [<xref ref-type="bibr" rid="ref52">52</xref>-<xref ref-type="bibr" rid="ref56">56</xref>]. These studies primarily assessed the daily experiences, health, and well-being of older adults. All but 2 studies [<xref ref-type="bibr" rid="ref57">57</xref>,<xref ref-type="bibr" rid="ref58">58</xref>] that targeted the general adult population included community-dwelling older adults aged 60 years or older, with sample sizes ranging from 173 to 477. The 2 studies that included the entire adult population showed age-specific characteristics by categorizing them into young, middle, and older adults, with the cutoff for older adults being 60 years or older [<xref ref-type="bibr" rid="ref58">58</xref>] and 65 years or older [<xref ref-type="bibr" rid="ref57">57</xref>].</p>
        <fig id="figure1" position="float">
          <label>Figure 1</label>
          <caption>
            <p>PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) flow diagram outlining the search and review process.</p>
          </caption>
          <graphic xlink:href="jmir_v27i1e66324_fig1.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
        </fig>
        <p>Among the variables mainly used as outcomes of social connectedness, loneliness accounted for the largest proportion at 30% (14/43), followed by social interaction or social encounter at 12% (5/43), and interaction quality or interpersonal relationship quality at 9% (4/43). The structural dimension of social connectedness (ie, social accompaniment and social interaction) was related to the functional dimension (ie, loneliness) [<xref ref-type="bibr" rid="ref27">27</xref>,<xref ref-type="bibr" rid="ref28">28</xref>,<xref ref-type="bibr" rid="ref46">46</xref>,<xref ref-type="bibr" rid="ref48">48</xref>-<xref ref-type="bibr" rid="ref50">50</xref>,<xref ref-type="bibr" rid="ref54">54</xref>,<xref ref-type="bibr" rid="ref56">56</xref>,<xref ref-type="bibr" rid="ref59">59</xref>] and quality dimension (ie, interaction quality) [<xref ref-type="bibr" rid="ref34">34</xref>,<xref ref-type="bibr" rid="ref52">52</xref>]. In addition, loneliness was associated with various factors such as individual factors (ie, age, gender, race, and ethnicity) [<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref50">50</xref>,<xref ref-type="bibr" rid="ref57">57</xref>], biological markers related to inflammation [<xref ref-type="bibr" rid="ref45">45</xref>], psychosocial factors (ie, need to belong, positive and negative affect, and anxiety) [<xref ref-type="bibr" rid="ref28">28</xref>,<xref ref-type="bibr" rid="ref44">44</xref>,<xref ref-type="bibr" rid="ref60">60</xref>], and contextual factors such as location [<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref49">49</xref>]. Social interaction was associated with individual personality (ie, daily extraversion and neuroticism) [<xref ref-type="bibr" rid="ref41">41</xref>] and well-being indicators (ie, mild cognitive impairment and fatigue) [<xref ref-type="bibr" rid="ref47">47</xref>,<xref ref-type="bibr" rid="ref55">55</xref>].</p>
        <p>The eligibility criteria common to all studies was community-dwelling older adults. Based on the original data criteria, study-specific criteria included that eligible participants were not institutionalized [<xref ref-type="bibr" rid="ref15">15</xref>,<xref ref-type="bibr" rid="ref41">41</xref>-<xref ref-type="bibr" rid="ref47">47</xref>], not working full-time [<xref ref-type="bibr" rid="ref26">26</xref>-<xref ref-type="bibr" rid="ref40">40</xref>], or involved in a prosocial program [<xref ref-type="bibr" rid="ref61">61</xref>]. In terms of physical function or disease, exclusion criteria included visual or auditory impairments [<xref ref-type="bibr" rid="ref15">15</xref>,<xref ref-type="bibr" rid="ref41">41</xref>-<xref ref-type="bibr" rid="ref47">47</xref>,<xref ref-type="bibr" rid="ref52">52</xref>-<xref ref-type="bibr" rid="ref56">56</xref>,<xref ref-type="bibr" rid="ref62">62</xref>], active psychiatric symptomatology [<xref ref-type="bibr" rid="ref15">15</xref>,<xref ref-type="bibr" rid="ref41">41</xref>-<xref ref-type="bibr" rid="ref47">47</xref>], cognitive impairment or diagnosis of dementia [<xref ref-type="bibr" rid="ref15">15</xref>,<xref ref-type="bibr" rid="ref41">41</xref>-<xref ref-type="bibr" rid="ref47">47</xref>,<xref ref-type="bibr" rid="ref58">58</xref>-<xref ref-type="bibr" rid="ref60">60</xref>,<xref ref-type="bibr" rid="ref62">62</xref>], nonambulatory status [<xref ref-type="bibr" rid="ref15">15</xref>,<xref ref-type="bibr" rid="ref41">41</xref>-<xref ref-type="bibr" rid="ref47">47</xref>], and disabilities in activities of daily living [<xref ref-type="bibr" rid="ref32">32</xref>] (<xref ref-type="supplementary-material" rid="app4">Multimedia Appendix 4</xref> [<xref ref-type="bibr" rid="ref15">15</xref>,<xref ref-type="bibr" rid="ref26">26</xref>-<xref ref-type="bibr" rid="ref75">75</xref>]).</p>
        <p>In terms of quality, according to the MMAT ratings, most studies met 100% of the criteria (*****, n=30), 8 studies achieved 80% (****), and 5 studies met 60% (***) of the criteria (<xref ref-type="supplementary-material" rid="app5">Multimedia Appendix 5</xref>).</p>
      </sec>
      <sec>
        <title>EMA of Social Connectedness and Other Contextual Variables</title>
        <p>As illustrated in <xref ref-type="supplementary-material" rid="app6">Multimedia Appendix 6</xref>, most studies (38/43, 88%), except for 5 studies [<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref44">44</xref>,<xref ref-type="bibr" rid="ref45">45</xref>,<xref ref-type="bibr" rid="ref57">57</xref>,<xref ref-type="bibr" rid="ref63">63</xref>], focused on the structural dimension of social connectedness. These studies investigated whether an individual was engaged in social contact or interaction at a specific time. Furthermore, 17 studies (17/43, 40%) addressed the functional dimension, all of which addressed loneliness [<xref ref-type="bibr" rid="ref27">27</xref>-<xref ref-type="bibr" rid="ref29">29</xref>,<xref ref-type="bibr" rid="ref43">43</xref>-<xref ref-type="bibr" rid="ref46">46</xref>,<xref ref-type="bibr" rid="ref48">48</xref>-<xref ref-type="bibr" rid="ref50">50</xref>,<xref ref-type="bibr" rid="ref54">54</xref>,<xref ref-type="bibr" rid="ref56">56</xref>,<xref ref-type="bibr" rid="ref57">57</xref>,<xref ref-type="bibr" rid="ref59">59</xref>,<xref ref-type="bibr" rid="ref60">60</xref>,<xref ref-type="bibr" rid="ref63">63</xref>] except for 1 study that addressed social exchange [<xref ref-type="bibr" rid="ref40">40</xref>]. The quality dimension covered in 16 studies (16/43, 37%) included assessments of the quality of social interactions [<xref ref-type="bibr" rid="ref15">15</xref>,<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref46">46</xref>,<xref ref-type="bibr" rid="ref47">47</xref>,<xref ref-type="bibr" rid="ref52">52</xref>,<xref ref-type="bibr" rid="ref58">58</xref>,<xref ref-type="bibr" rid="ref64">64</xref>], pleasantness of encounters or positive encounters [<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref33">33</xref>,<xref ref-type="bibr" rid="ref34">34</xref>,<xref ref-type="bibr" rid="ref38">38</xref>,<xref ref-type="bibr" rid="ref56">56</xref>,<xref ref-type="bibr" rid="ref65">65</xref>], interpersonal tension [<xref ref-type="bibr" rid="ref35">35</xref>], stress or negative social encounters [<xref ref-type="bibr" rid="ref26">26</xref>,<xref ref-type="bibr" rid="ref37">37</xref>,<xref ref-type="bibr" rid="ref65">65</xref>], and stressful discussions [<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref34">34</xref>,<xref ref-type="bibr" rid="ref38">38</xref>]. Furthermore, 2 studies [<xref ref-type="bibr" rid="ref46">46</xref>,<xref ref-type="bibr" rid="ref56">56</xref>] explored all 3 dimensions of social connectedness.</p>
        <p>Each dimension of the multifactorial construct of social connectedness was assessed using 1 or 2 questions. Several studies required participants to enumerate their social partners during the initial interview, specifying whether they had been in contact with any of these partners in the preceding 3 hours. Subsequently, these studies tracked whether participants had contact with the listed social partners at each assessed moment [<xref ref-type="bibr" rid="ref26">26</xref>-<xref ref-type="bibr" rid="ref40">40</xref>]. While studies examining social relationships have considered a wider range of interaction types, such as in-person, phone, computer, or text [<xref ref-type="bibr" rid="ref15">15</xref>,<xref ref-type="bibr" rid="ref26">26</xref>-<xref ref-type="bibr" rid="ref28">28</xref>,<xref ref-type="bibr" rid="ref30">30</xref>,<xref ref-type="bibr" rid="ref33">33</xref>,<xref ref-type="bibr" rid="ref34">34</xref>,<xref ref-type="bibr" rid="ref39">39</xref>,<xref ref-type="bibr" rid="ref41">41</xref>,<xref ref-type="bibr" rid="ref47">47</xref>-<xref ref-type="bibr" rid="ref56">56</xref>, <xref ref-type="bibr" rid="ref58">58</xref>,<xref ref-type="bibr" rid="ref60">60</xref>-<xref ref-type="bibr" rid="ref62">62</xref>,<xref ref-type="bibr" rid="ref65">65</xref>], some studies have focused on in-person [<xref ref-type="bibr" rid="ref48">48</xref>-<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref62">62</xref>].</p>
        <p>Other variables measured by EMA included context, such as location [<xref ref-type="bibr" rid="ref32">32</xref>,<xref ref-type="bibr" rid="ref43">43</xref>,<xref ref-type="bibr" rid="ref48">48</xref>-<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref53">53</xref>,<xref ref-type="bibr" rid="ref66">66</xref>], activity or behavior [<xref ref-type="bibr" rid="ref28">28</xref>,<xref ref-type="bibr" rid="ref32">32</xref>,<xref ref-type="bibr" rid="ref34">34</xref>,<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref46">46</xref>,<xref ref-type="bibr" rid="ref47">47</xref>,<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref61">61</xref>,<xref ref-type="bibr" rid="ref63">63</xref>], sedentary time [<xref ref-type="bibr" rid="ref36">36</xref>], and time spent exercising and outdoors [<xref ref-type="bibr" rid="ref60">60</xref>], and cognitive function [<xref ref-type="bibr" rid="ref15">15</xref>,<xref ref-type="bibr" rid="ref43">43</xref>]. In addition, concurrent positive or negative moods [<xref ref-type="bibr" rid="ref26">26</xref>,<xref ref-type="bibr" rid="ref29">29</xref>-<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref34">34</xref>-<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref44">44</xref>,<xref ref-type="bibr" rid="ref46">46</xref>,<xref ref-type="bibr" rid="ref54">54</xref>,<xref ref-type="bibr" rid="ref56">56</xref>,<xref ref-type="bibr" rid="ref57">57</xref>,<xref ref-type="bibr" rid="ref59">59</xref>-<xref ref-type="bibr" rid="ref63">63</xref>,<xref ref-type="bibr" rid="ref67">67</xref>], pain [<xref ref-type="bibr" rid="ref33">33</xref>,<xref ref-type="bibr" rid="ref37">37</xref>,<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref57">57</xref>], fatigue [<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref57">57</xref>], stress [<xref ref-type="bibr" rid="ref41">41</xref>,<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref51">51</xref>], and sense of relatedness [<xref ref-type="bibr" rid="ref52">52</xref>,<xref ref-type="bibr" rid="ref61">61</xref>] were also assessed.</p>
      </sec>
      <sec>
        <title>Social Connectedness at Trait-Level Assessment</title>
        <p>Most studies (40/43, 93%) addressed at least 1 dimension of social connectedness at trait-level assessment: the structural dimension, such as marital status, living arrangement, or social network (40/43, 93%); the functional dimension, such as loneliness or social support (6/43, 14%); and the quality dimension, such as negative social interaction and social strain (4/43, 9%). Each study used this information to describe the sample characteristics at trait-level assessment, to compare outcomes measured by EMA, or to include them as control variables in the analysis (<xref ref-type="supplementary-material" rid="app7">Multimedia Appendix 7</xref>).</p>
      </sec>
      <sec>
        <title>EMA Protocols</title>
        <p><xref ref-type="supplementary-material" rid="app8">Multimedia Appendix 8</xref> [<xref ref-type="bibr" rid="ref15">15</xref>,<xref ref-type="bibr" rid="ref26">26</xref>-<xref ref-type="bibr" rid="ref75">75</xref>] summarizes details of EMA varied across data sources. Among the 15 data sources, the design of EMA prompts was categorized as follows: 6 data sources employed a quasi-random scheduling method for delivering prompts [<xref ref-type="bibr" rid="ref15">15</xref>,<xref ref-type="bibr" rid="ref26">26</xref>-<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref58">58</xref>,<xref ref-type="bibr" rid="ref60">60</xref>,<xref ref-type="bibr" rid="ref62">62</xref>], while 4 data sources used a self-determined approach in which participants responded at a time of their choosing before bedtime [<xref ref-type="bibr" rid="ref57">57</xref>,<xref ref-type="bibr" rid="ref59">59</xref>,<xref ref-type="bibr" rid="ref63">63</xref>,<xref ref-type="bibr" rid="ref65">65</xref>]. Furthermore, 2 data sources used a completely randomized schedule [<xref ref-type="bibr" rid="ref61">61</xref>,<xref ref-type="bibr" rid="ref66">66</xref>]. Event-contingent designs, in which specific events triggered prompts [<xref ref-type="bibr" rid="ref52">52</xref>-<xref ref-type="bibr" rid="ref56">56</xref>] and fixed time [<xref ref-type="bibr" rid="ref64">64</xref>] were each in 1 data source, respectively. In addition, 1 data source did not specify the prompt design method [<xref ref-type="bibr" rid="ref61">61</xref>].</p>
        <p>The frequency of survey administration ranged from 1 to 7 times daily, with the assessment periods lasting between 5 and 25 days. Most data sources reported surveys via smartphones, although 6 data sources did not specify the device type used [<xref ref-type="bibr" rid="ref57">57</xref>,<xref ref-type="bibr" rid="ref61">61</xref>,<xref ref-type="bibr" rid="ref62">62</xref>,<xref ref-type="bibr" rid="ref65">65</xref>-<xref ref-type="bibr" rid="ref67">67</xref>]. Digital devices were used to capture voice data to estimate conversation frequency [<xref ref-type="bibr" rid="ref30">30</xref>] and to collect accelerometer data to assess physical activity [<xref ref-type="bibr" rid="ref36">36</xref>]. All but 9 data sources [<xref ref-type="bibr" rid="ref52">52</xref>-<xref ref-type="bibr" rid="ref57">57</xref>,<xref ref-type="bibr" rid="ref59">59</xref>-<xref ref-type="bibr" rid="ref61">61</xref>,<xref ref-type="bibr" rid="ref63">63</xref>,<xref ref-type="bibr" rid="ref64">64</xref>,<xref ref-type="bibr" rid="ref66">66</xref>,<xref ref-type="bibr" rid="ref67">67</xref>] described details regarding participant training before commencing actual data collection. Depending on participant responses, reminders were issued in a predetermined manner [<xref ref-type="bibr" rid="ref48">48</xref>-<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref57">57</xref>,<xref ref-type="bibr" rid="ref59">59</xref>,<xref ref-type="bibr" rid="ref60">60</xref>,<xref ref-type="bibr" rid="ref63">63</xref>]. In addition, 1 data source took proactive measures by contacting participants if they missed 3 consecutive surveys, to address any technical or adherence problems [<xref ref-type="bibr" rid="ref60">60</xref>]. Data were included in the analysis if they were submitted within a pre-established maximum time frame.</p>
      </sec>
      <sec>
        <title>Definition and Rate of Compliance and Adherence to EMA</title>
        <p>As illustrated in <xref ref-type="supplementary-material" rid="app9">Multimedia Appendix 9</xref>, studies used the terms completion, compliance, and adherence. In 1 study [<xref ref-type="bibr" rid="ref49">49</xref>], adherence was defined as the number of valid EMAs divided by the potential maximum EMA number. The completion rate for studies in the overall adult population was 89% [<xref ref-type="bibr" rid="ref58">58</xref>], while those targeting only older adults—based on 2 data sources—reported completion rates of 70% or higher [<xref ref-type="bibr" rid="ref28">28</xref>,<xref ref-type="bibr" rid="ref33">33</xref>,<xref ref-type="bibr" rid="ref61">61</xref>]. Among the older adult population, based on 5 data sources, compliance with EMA protocol instructions exceeded 82% [<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref44">44</xref>,<xref ref-type="bibr" rid="ref46">46</xref>,<xref ref-type="bibr" rid="ref47">47</xref>,<xref ref-type="bibr" rid="ref54">54</xref>,<xref ref-type="bibr" rid="ref56">56</xref>,<xref ref-type="bibr" rid="ref57">57</xref>,<xref ref-type="bibr" rid="ref63">63</xref>,<xref ref-type="bibr" rid="ref66">66</xref>]. Although some studies used the same data source, the number of valid EMAs varied depending on the specific aims of each study, resulting in differences in compliance rates [<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref44">44</xref>,<xref ref-type="bibr" rid="ref46">46</xref>,<xref ref-type="bibr" rid="ref47">47</xref>]. Only 1 study presented a predefined acceptable adherence rate of at least 75%, with a 7-day adherence rate of 83.9% [<xref ref-type="bibr" rid="ref60">60</xref>]. In contrast, a study using the Chicago Health and Activity Space in Real-Time data with a 6-wave design had an adherence rate of 58% [<xref ref-type="bibr" rid="ref49">49</xref>]. In studies that combined beep and end-of-day surveys, end-of-day surveys showed lower levels of compliance compared to beep surveys [<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref44">44</xref>,<xref ref-type="bibr" rid="ref46">46</xref>,<xref ref-type="bibr" rid="ref47">47</xref>], whereas it was higher in the evening compared with the morning or afternoon [<xref ref-type="bibr" rid="ref60">60</xref>].</p>
        <p>Few studies have specifically identified reasons for participants’ lack of complete EMA evaluations. Among those that did, technical issues with EMA [<xref ref-type="bibr" rid="ref32">32</xref>,<xref ref-type="bibr" rid="ref50">50</xref>,<xref ref-type="bibr" rid="ref51">51</xref>] and misunderstandings of the instructions [<xref ref-type="bibr" rid="ref52">52</xref>,<xref ref-type="bibr" rid="ref55">55</xref>] were commonly reported. Although respondents received direct training, including on how to use devices, 15% (72/455) of respondents were unable to complete the EMA due to unfamiliarity with using smartphones [<xref ref-type="bibr" rid="ref51">51</xref>].</p>
      </sec>
      <sec>
        <title>Conceptual Summary of Social Connectedness</title>
        <p>As illustrated in <xref ref-type="table" rid="table1">Table 1</xref>, we summarized how the selected studies addressed the 3 dimensions of social connectedness in their EMA assessments, using the framework proposed by Holt-Lunstad et al [<xref ref-type="bibr" rid="ref8">8</xref>]. The table distinguishes between trait-level characteristics and dynamic, real-time measures captured through EMA, which include both momentary snapshots and daily summaries. It also highlights the role of contextual factors in enhancing the understanding of social connectedness. Specifically, EMA captures the structural dimension through indicators such as the occurrence, frequency, characteristics of social partners, and the purpose of interactions; the functional dimension through measures of loneliness and the exchange of emotional or instrumental support; and the quality dimension through the subjective evaluation of interactions, including pleasantness, stress, and interpersonal tension. While many indicators are measured consistently across time units, certain aspects (eg, stressful discussions) were assessed only at specific moments due to the limitations of self-reporting or observation within short time frames. Overall, these findings underscore social connectedness in later life as a dynamic construct shaped by the interplay of structure, function, and quality across varying contexts and temporal scales.</p>
        <table-wrap position="float" id="table1">
          <label>Table 1</label>
          <caption>
            <p>Conceptual summary of social connectedness.</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="100"/>
            <col width="210"/>
            <col width="190"/>
            <col width="180"/>
            <col width="150"/>
            <col width="0"/>
            <col width="170"/>
            <thead>
              <tr valign="top">
                <td>Dimension</td>
                <td>Trait-level assessment</td>
                <td colspan="4">Ecological momentary assessment</td>
                <td>Context</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>Momentary (right now)</td>
                <td>Since the last assessment</td>
                <td>Today as a whole</td>
                <td colspan="2">
                  <break/>
                </td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td>Structure</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Living arrangement</p>
                      <list>
                        <list-item>
                          <p>
                    Marital status
                  </p>
                        </list-item>
                        <list-item>
                          <p>
                    Household composition
                  </p>
                        </list-item>
                      </list>
                    </list-item>
                    <list-item>
                      <p>Extent and frequency of social connection</p>
                      <list>
                        <list-item>
                          <p>
                    Social network size
                  </p>
                        </list-item>
                        <list-item>
                          <p>
                    Proportion time spent alone
                  </p>
                        </list-item>
                        <list-item>
                          <p>
                    Social interaction average frequency
                  </p>
                        </list-item>
                        <list-item>
                          <p>
                    Leadership role in prosocial activity
                  </p>
                        </list-item>
                        <list-item>
                          <p>
                    The number of close social relationships
                  </p>
                        </list-item>
                        <list-item>
                          <p>
                    The overall contact frequency with relationship partners
                  </p>
                        </list-item>
                      </list>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Social interaction</p>
                      <list>
                        <list-item>
                          <p>
                    Occurrence
                  </p>
                        </list-item>
                        <list-item>
                          <p>
                    Duration (interaction time)
                  </p>
                        </list-item>
                        <list-item>
                          <p>
                    Social partner characteristics
                  </p>
                        </list-item>
                        <list-item>
                          <p>
                    Modality
                  </p>
                        </list-item>
                        <list-item>
                          <p>
                    Interaction purpose
                  </p>
                        </list-item>
                      </list>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Social interaction</p>
                      <list>
                        <list-item>
                          <p>
                    Occurrence
                  </p>
                        </list-item>
                        <list-item>
                          <p>
                    Frequency
                  </p>
                        </list-item>
                        <list-item>
                          <p>
                    Social partner characteristics
                  </p>
                        </list-item>
                        <list-item>
                          <p>
                    Modality
                  </p>
                        </list-item>
                      </list>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Social interaction</p>
                      <list>
                        <list-item>
                          <p>
                    Occurrence
                  </p>
                        </list-item>
                        <list-item>
                          <p>
                    Duration (time spent alone)
                  </p>
                        </list-item>
                      </list>
                    </list-item>
                  </list>
                </td>
                <td colspan="2">
                  <list list-type="bullet">
                    <list-item>
                      <p>Behavioral context</p>
                      <list>
                        <list-item>
                          <p>
                    Engagement in daily activity
                  </p>
                        </list-item>
                        <list-item>
                          <p>
                    Physical activity and sedentary time<sup>a</sup>
                  </p>
                        </list-item>
                        <list-item>
                          <p>
                    Outdoor activity and exercise time
                  </p>
                        </list-item>
                        <list-item>
                          <p>
                    Social media use
                  </p>
                        </list-item>
                      </list>
                    </list-item>
                    <list-item>
                      <p>Functional context</p>
                      <list>
                        <list-item>
                          <p>
                    Functional ability
                  </p>
                        </list-item>
                        <list-item>
                          <p>
                    Cognitive function
                  </p>
                        </list-item>
                      </list>
                    </list-item>
                    <list-item>
                      <p>Environmental context</p>
                      <list>
                        <list-item>
                          <p>
                    Location
                  </p>
                        </list-item>
                      </list>
                    </list-item>
                  </list>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>Function</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Loneliness</p>
                    </list-item>
                    <list-item>
                      <p>Social support</p>
                      <list>
                        <list-item>
                          <p>
                    Emotional, instrumental, or informational support
                  </p>
                        </list-item>
                      </list>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Loneliness</p>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Loneliness</p>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Loneliness</p>
                    </list-item>
                    <list-item>
                      <p>Provision and receipt of support and advice</p>
                    </list-item>
                  </list>
                </td>
                <td colspan="2">
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>Quality</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Social interaction quality</p>
                      <list>
                        <list-item>
                          <p>
                    Social strain
                  </p>
                        </list-item>
                        <list-item>
                          <p>
                    Negative social interaction
                  </p>
                        </list-item>
                        <list-item>
                          <p>
                    Social network quality
                  </p>
                        </list-item>
                      </list>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Social interaction quality</p>
                      <list>
                        <list-item>
                          <p>
                    Pleasant
                  </p>
                        </list-item>
                        <list-item>
                          <p>
                    Valence, satisfaction, feeling
                  </p>
                        </list-item>
                      </list>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Stressful discussion</p>
                    </list-item>
                    <list-item>
                      <p>Interpersonal tensions</p>
                    </list-item>
                    <list-item>
                      <p>Social interaction quality</p>
                      <list>
                        <list-item>
                          <p>
                    Pleasant, unpleasant, or both or neutral
                  </p>
                        </list-item>
                        <list-item>
                          <p>
                    Positive or negative
                  </p>
                        </list-item>
                      </list>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Social interaction quality</p>
                      <list>
                        <list-item>
                          <p>
                    Positive or negative
                  </p>
                        </list-item>
                      </list>
                    </list-item>
                  </list>
                </td>
                <td colspan="2">
                  <break/>
                </td>
              </tr>
            </tbody>
          </table>
          <table-wrap-foot>
            <fn id="table1fn1">
              <p><sup>a</sup>Indicators using accelerometer assessment.</p>
            </fn>
          </table-wrap-foot>
        </table-wrap>
      </sec>
    </sec>
    <sec sec-type="discussion">
      <title>Discussion</title>
      <sec>
        <title>Principal Findings</title>
        <p>In this integrative review, we identified and evaluated studies that assessed social connectedness in older adults using EMA. We examined how EMA was used to assess the multifactorial construct of social connectedness and gather contextual information. In addition, we highlighted the procedural elements of EMA identified in each study. Overall, using EMA to measure social connectedness in community-dwelling older adults is considered feasible, and refining these procedural elements will enhance the utility of EMA for this demographic. With the rapid advancement of digital technologies and an increasing emphasis on data collection methods that are more centered around participants’ needs and preferences, EMA methods are expected to become more personalized and user-friendly. This review is particularly timely as it is among the first to comprehensively evaluate the use of EMA in measuring social connectedness specifically within the older adult population. By examining the current state of EMA methods and identifying gaps in these approaches, this review provides valuable insights that can guide future research in this area.</p>
        <p>In our review, the structural dimension of social connectedness, such as social accompaniment or interaction, was most frequently examined in EMA studies. Only 2 studies [<xref ref-type="bibr" rid="ref46">46</xref>,<xref ref-type="bibr" rid="ref56">56</xref>] addressed all 3 dimensions—structural, functional, and quality—while the others focused on just 1 or 2 dimensions. A multifactorial approach to social connectedness emerged as the strongest predictor of mortality risk, comparable in magnitude with well-recognized health determinants like alcohol consumption and smoking [<xref ref-type="bibr" rid="ref76">76</xref>]. In addition, this multifactorial approach aids in the appropriate allocation of limited resources for social support interventions [<xref ref-type="bibr" rid="ref8">8</xref>,<xref ref-type="bibr" rid="ref77">77</xref>]. Despite the benefits of a multifactorial approach, previous studies have often focused on limited dimensions of social connectedness. Many of the studies included in this review were secondary analyses based on the same dataset, which may have resulted in limited variable selection and a lack of diversity in variables. Future research should consider adopting a multifactorial approach to achieve a more nuanced understanding of social connectedness, thereby enabling a more comprehensive reflection and interpretation of its components.</p>
        <p>Across the 43 studies reviewed, the EMA protocols demonstrated consistency in methodology, largely because most studies adopted established protocols from large-scale projects. These protocols outlined the optimal frequency, duration, and intervals for data collection, as well as the devices used. They also featured carefully selected questions designed to boost participant response rates and enhance data accuracy, with 1-2 items being used intensively in EMA. Although there is increasing evidence suggesting that fewer items may still provide adequate validity [<xref ref-type="bibr" rid="ref78">78</xref>,<xref ref-type="bibr" rid="ref79">79</xref>], concerns remain about whether these items sufficiently capture the study’s target construct and provide enough information. Internal consistency (eg, Cronbach α) often increases as the number of items increases [<xref ref-type="bibr" rid="ref80">80</xref>]. Yet, a previous study pointed out that an increased number of items can also increase participant burden and compromise the data quantity and quality in the experience sampling method [<xref ref-type="bibr" rid="ref81">81</xref>]. Therefore, when selecting items for EMA, balancing internal consistency and participant burden is essential for effectively assessing social connectedness through EMA in older adults. For aspects that cannot be measured in real time, such as social network composition, supplementing EMA with methods like trait-level assessment could be a viable alternative.</p>
        <p>Adopting individualized protocols and collecting real-time information were key to ensuring ecological validity. Most studies aimed to accommodate participants’ circumstances better and minimize disruption to their daily routines. In addition, gathering real-time data on participants’ locations [<xref ref-type="bibr" rid="ref32">32</xref>,<xref ref-type="bibr" rid="ref43">43</xref>,<xref ref-type="bibr" rid="ref48">48</xref>-<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref53">53</xref>,<xref ref-type="bibr" rid="ref66">66</xref>], physical or social contexts [<xref ref-type="bibr" rid="ref28">28</xref>,<xref ref-type="bibr" rid="ref32">32</xref>,<xref ref-type="bibr" rid="ref34">34</xref>,<xref ref-type="bibr" rid="ref36">36</xref>, <xref ref-type="bibr" rid="ref46">46</xref>,<xref ref-type="bibr" rid="ref47">47</xref>,<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref60">60</xref>,<xref ref-type="bibr" rid="ref61">61</xref>,<xref ref-type="bibr" rid="ref63">63</xref>], cognitive function [<xref ref-type="bibr" rid="ref15">15</xref>,<xref ref-type="bibr" rid="ref43">43</xref>], physical symptoms [<xref ref-type="bibr" rid="ref33">33</xref>,<xref ref-type="bibr" rid="ref37">37</xref>,<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref57">57</xref>], and mood [<xref ref-type="bibr" rid="ref26">26</xref>,<xref ref-type="bibr" rid="ref29">29</xref>-<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref34">34</xref>-<xref ref-type="bibr" rid="ref40">40</xref>, <xref ref-type="bibr" rid="ref44">44</xref>,<xref ref-type="bibr" rid="ref46">46</xref>,<xref ref-type="bibr" rid="ref54">54</xref>,<xref ref-type="bibr" rid="ref56">56</xref>,<xref ref-type="bibr" rid="ref57">57</xref>,<xref ref-type="bibr" rid="ref59">59</xref>-<xref ref-type="bibr" rid="ref63">63</xref>,<xref ref-type="bibr" rid="ref67">67</xref>] played a crucial role in understanding the contexts of social connectedness among older adults. However, it is noteworthy that while the studies defined the types of social interactions, they reported the results without specifying the mode of social interaction, such as in-person versus technology-mediated interactions. Some studies specifically focused on in-person interactions, considering technology-mediated interactions either irrelevant to well-being [<xref ref-type="bibr" rid="ref54">54</xref>] or representing a minor portion of the data (eg, 8% [1198/15,479 encounters] text messaging) [<xref ref-type="bibr" rid="ref30">30</xref>]. Smartphone ownership rates have been increasing globally, particularly among US adults aged 65 years and older, rising from 13% in 2012 to 61% in 2021. Similarly, internet usage among older adults has followed a comparable trend [<xref ref-type="bibr" rid="ref82">82</xref>]. In particular, older adults’ technology-based social experiences have increased since the COVID-19 pandemic, and are likely to differ compared with prepandemic times [<xref ref-type="bibr" rid="ref83">83</xref>], which suggests that this may have led to changes in social interaction modality and relationships. Given that most studies were conducted before the pandemic or during the pandemic, future research designs should carefully consider individual circumstances and the changing social landscape to provide a nuanced understanding of real-time social connectedness in the older adult population.</p>
        <p>Most studies have relied on self-reported outcomes from older participants using digital devices. Real-time data collection through these devices may face challenges due to technical issues (eg, malfunctions), physical limitations (eg, hearing impairment), and cognitive barriers (eg, forgetfulness) [<xref ref-type="bibr" rid="ref84">84</xref>]. Given the steady aging of the global population, the potential for physical or cognitive impairments in older adults cannot be ignored [<xref ref-type="bibr" rid="ref85">85</xref>,<xref ref-type="bibr" rid="ref86">86</xref>]. Furthermore, data from self-report surveys might be skewed by participants’ concerns about the stigma associated with social isolation or loneliness [<xref ref-type="bibr" rid="ref87">87</xref>], which can hinder the identification of individuals with low social connectedness. As a promising alternative, unobtrusive passive sensing technologies such as GPS, accelerometers, light sensors, phone usage, voice monitors, and vital signs can minimize the need for active participant involvement in specific situational settings, potentially circumventing many data collection issues [<xref ref-type="bibr" rid="ref88">88</xref>,<xref ref-type="bibr" rid="ref89">89</xref>]. As an example, mobile data of phone activity (eg, SMS text messages and call logs) was used to infer communication (ie, social interactions) [<xref ref-type="bibr" rid="ref90">90</xref>]. In addition, passive data have been used to predict loneliness [<xref ref-type="bibr" rid="ref91">91</xref>-<xref ref-type="bibr" rid="ref93">93</xref>], for example, objective physiological parameters (ie, heart rate, heart rate variability, physical activity, and sleep) collected with smartwatches to build a model to predict loneliness [<xref ref-type="bibr" rid="ref93">93</xref>]. These prediction algorithms could be further developed to enhance support programs. Some studies included in the review showed the potential to integrate passive data from voice recordings [<xref ref-type="bibr" rid="ref30">30</xref>] or wearable devices to measure social connectedness [<xref ref-type="bibr" rid="ref36">36</xref>]. The combination of various passive metrics in existing approaches is expected to yield complementary insights [<xref ref-type="bibr" rid="ref88">88</xref>,<xref ref-type="bibr" rid="ref89">89</xref>]. However, passive measures have limitations in fully capturing subjective dimensions (ie, functional and quality dimensions of social connectedness) [<xref ref-type="bibr" rid="ref94">94</xref>,<xref ref-type="bibr" rid="ref95">95</xref>], therefore, it is necessary to use active and passive data complementarily.</p>
        <p>The results of this review highlight important considerations in future research design. First, our analysis showed that social connectedness is not merely the presence or frequency of encounters but involves unidirectional or bidirectional relationships across structural, functional, and quality dimensions. These dimensions were closely related to personal [<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref50">50</xref>,<xref ref-type="bibr" rid="ref57">57</xref>], biological [<xref ref-type="bibr" rid="ref45">45</xref>], psychosocial [<xref ref-type="bibr" rid="ref28">28</xref>,<xref ref-type="bibr" rid="ref44">44</xref>,<xref ref-type="bibr" rid="ref60">60</xref>], and contextual factors [<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref49">49</xref>]. Identifying additional contextual factors is crucial to understanding social connectedness and pinpointing those at risk, thereby guiding the development of effective intervention strategies. By more precisely assessing factors that require intervention, tailored support can be provided to enhance social connectedness in older adults. However, current research often overlooks the multifaceted nature of social connectedness, especially its structural, functional, and quality dimensions. Furthermore, social connectedness measures for older adults are often modeled after those for younger adults, which may not account for unique factors like retirement [<xref ref-type="bibr" rid="ref96">96</xref>,<xref ref-type="bibr" rid="ref97">97</xref>]. Therefore, a comprehensive understanding of social connectedness is necessary, with careful attention to selecting relevant variables to better understand the experiences of older adults.</p>
        <p>Second, the older adult population showed relatively high EMA compliance and adherence rates. Some studies have also shown that older adults have higher reporting fidelity and accuracy than young adults [<xref ref-type="bibr" rid="ref13">13</xref>,<xref ref-type="bibr" rid="ref98">98</xref>]. Therefore, EMA studies targeting older adults are likely to secure reliable data. However, technical challenges remain in conducting EMA using digital devices, suggesting that older adults’ digital access and familiarity with devices may affect compliance [<xref ref-type="bibr" rid="ref48">48</xref>-<xref ref-type="bibr" rid="ref51">51</xref>]. Although not explicitly discussed in the included studies, it is possible that discomfort with unfamiliar digital devices may negatively affect EMA compliance [<xref ref-type="bibr" rid="ref99">99</xref>]. Therefore, it is important to improve older adults’ digital accessibility and device usage skills and improve research methods. Typically, the training session is used to familiarize participants with how to use the device. However, incorporating hands-on training and simple EMA simulations (eg, 1- to 2-day mock surveys) in addition to basic training is considered a more effective approach. In addition, when analyzing the changes in EMA compliance according to older adults’ daily schedule, the “end-of-day” survey showed lower compliance than the “beep survey” [<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref44">44</xref>,<xref ref-type="bibr" rid="ref46">46</xref>,<xref ref-type="bibr" rid="ref47">47</xref>]. These results are consistent with those of previous studies reporting significantly lower survey response rates in the evening than in the morning or afternoon [<xref ref-type="bibr" rid="ref100">100</xref>]. Meanwhile, 1 study showed that the response rate in the night survey was lower than the morning and evening surveys [<xref ref-type="bibr" rid="ref60">60</xref>]. The variation across studies suggests that temporal variations in motivation, activity level, context, or individual factors may have influenced older adults’ willingness and opportunity to respond to EMA [<xref ref-type="bibr" rid="ref100">100</xref>]. Therefore, future EMA studies should investigate participants’ experiences after the end of the study to better understand the context of response patterns. This will be an important step in establishing the EMA methodology as feasible and effective beyond understanding the social connectedness.</p>
      </sec>
      <sec>
        <title>Limitations</title>
        <p>This study has several limitations. First, although we included 5 databases, we did not include all possible databases, which may have resulted in missing some studies that met the inclusion criteria. Second, most of the studies used identical datasets, thus limiting the diversity of protocols available for analysis. Nevertheless, the provision of well-structured protocols in cohort studies with large sample sizes offers valuable insights, which are beneficial for designing future EMA studies in older adults. Finally, the study sample consisted of older adults who exhibit relatively good physical and cognitive functioning, which limits the generalizability of the findings. Therefore, the findings should be interpreted with caution. Future EMA studies should aim to explore the feasibility of EMA in more diverse and heterogeneous groups of the older adult population, such as those with lower levels of physical and cognitive functioning.</p>
      </sec>
      <sec>
        <title>Conclusions</title>
        <p>This study highlights the need for both conceptual and methodological refinements in using EMA to measure social connectedness among older adults. It is necessary to capture the multifactorial construct of social connectedness in real time, and the unique experience of EMA, particularly with digital devices, should be incorporated into the design process. Further research with diverse older adult populations is recommended to better understand and address barriers to adherence to EMA protocols for measuring social connectedness.</p>
      </sec>
    </sec>
  </body>
  <back>
    <app-group>
      <supplementary-material id="app1">
        <label>Multimedia Appendix 1</label>
        <p>PRISMA (Preferred Reporting Items for Systematic reviews and Meta-Analyses) checklist.</p>
        <media xlink:href="jmir_v27i1e66324_app1.docx" xlink:title="DOCX File , 24 KB"/>
      </supplementary-material>
      <supplementary-material id="app2">
        <label>Multimedia Appendix 2</label>
        <p>Search strategies.</p>
        <media xlink:href="jmir_v27i1e66324_app2.docx" xlink:title="DOCX File , 22 KB"/>
      </supplementary-material>
      <supplementary-material id="app3">
        <label>Multimedia Appendix 3</label>
        <p>Summary of included studies (n=43).</p>
        <media xlink:href="jmir_v27i1e66324_app3.docx" xlink:title="DOCX File , 47 KB"/>
      </supplementary-material>
      <supplementary-material id="app4">
        <label>Multimedia Appendix 4</label>
        <p>Inclusion and exclusion criteria by data source.</p>
        <media xlink:href="jmir_v27i1e66324_app4.docx" xlink:title="DOCX File , 38 KB"/>
      </supplementary-material>
      <supplementary-material id="app5">
        <label>Multimedia Appendix 5</label>
        <p>Quality evaluation of the selected studies.</p>
        <media xlink:href="jmir_v27i1e66324_app5.docx" xlink:title="DOCX File , 30 KB"/>
      </supplementary-material>
      <supplementary-material id="app6">
        <label>Multimedia Appendix 6</label>
        <p>Ecological momentary assessment of social connectedness and other contextual variables.</p>
        <media xlink:href="jmir_v27i1e66324_app6.docx" xlink:title="DOCX File , 29 KB"/>
      </supplementary-material>
      <supplementary-material id="app7">
        <label>Multimedia Appendix 7</label>
        <p>Trait-level assessment of social connectedness.</p>
        <media xlink:href="jmir_v27i1e66324_app7.docx" xlink:title="DOCX File , 24 KB"/>
      </supplementary-material>
      <supplementary-material id="app8">
        <label>Multimedia Appendix 8</label>
        <p>Ecological momentary assessment protocols.</p>
        <media xlink:href="jmir_v27i1e66324_app8.docx" xlink:title="DOCX File , 36 KB"/>
      </supplementary-material>
      <supplementary-material id="app9">
        <label>Multimedia Appendix 9</label>
        <p>Definition and rate of compliance and adherence used in selected studies.</p>
        <media xlink:href="jmir_v27i1e66324_app9.docx" xlink:title="DOCX File , 30 KB"/>
      </supplementary-material>
    </app-group>
    <glossary>
      <title>Abbreviations</title>
      <def-list>
        <def-item>
          <term id="abb1">CHART</term>
          <def>
            <p>Chicago Health and Activity Space in Real-Time</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb2">EMA</term>
          <def>
            <p>ecological momentary assessment</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb3">MeSH</term>
          <def>
            <p>Medical Subject Headings</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb4">MMAT</term>
          <def>
            <p>Mixed-Methods Appraisal Tool</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb5">PRISMA</term>
          <def>
            <p>Preferred Reporting Items for Systematic Reviews and Meta-Analyses</p>
          </def>
        </def-item>
      </def-list>
    </glossary>
    <ack>
      <p>This research was supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF), funded by the Ministry of Education (2020R1A6A1A03041989), the Institute for Innovation in Digital Healthcare, Yonsei University, and the Mo-Im Kim Nursing Research Institute, Yonsei University College of Nursing. We used ChatGPT (OpenAI) for grammar and language correction, but the chatbot was not used to generate any of the text, figures, appendices, or tables [<xref ref-type="bibr" rid="ref101">101</xref>].</p>
    </ack>
    <fn-group>
      <fn fn-type="con">
        <p>SC designed the study, searched and selected the articles, performed the quality assessment, analyzed and interpreted the articles, and drafted and revised the manuscript. HK searched and selected the articles, performed quality assessments, analyzed and interpreted the articles, and drafted the manuscript. JS designed the study, analyzed and interpreted the articles, and revised the manuscript. SHC provided critical review of the manuscript. JC designed the study, analyzed and interpreted the articles, and revised the manuscript for important intellectual content. All authors made substantial contributions to the study and approved the submitted version of the manuscript.</p>
      </fn>
      <fn fn-type="conflict">
        <p>None declared.</p>
      </fn>
    </fn-group>
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