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<article article-type="letter" dtd-version="2.0" xmlns:xlink="http://www.w3.org/1999/xlink">
  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JMIR</journal-id>
      <journal-id journal-id-type="nlm-ta">J Med Internet Res</journal-id>
      <journal-title>Journal of Medical Internet Research</journal-title>
      <issn pub-type="epub">1438-8871</issn>
      <publisher>
        <publisher-name>JMIR Publications</publisher-name>
        <publisher-loc>Toronto, Canada</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">v27i1e59976</article-id>
      <article-id pub-id-type="pmid">40920452</article-id>
      <article-id pub-id-type="doi">10.2196/59976</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Letter to the Editor</subject>
        </subj-group>
        <subj-group subj-group-type="article-type">
          <subject>Letter to the Editor</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>The Art of the Special Interest: Lexicon-Based Analysis of Longitudinal Changes in Language Patterns Among Neurodiverse Youth Designing Special Interest–Related Digital Art</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="editor">
          <name>
            <surname>Coristine</surname>
            <given-names>Andrew</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Rahman</surname>
            <given-names>Mohammad Mustaneer</given-names>
          </name>
        </contrib>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Toki</surname>
            <given-names>Eugenia</given-names>
          </name>
        </contrib>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Bhurawala</surname>
            <given-names>Habib</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib id="contrib1" contrib-type="author" corresp="yes">
          <name name-style="western">
            <surname>Campos-Castillo</surname>
            <given-names>Celeste</given-names>
          </name>
          <degrees>PhD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <address>
            <institution/>
            <institution>Department of Media and Information</institution>
            <institution>Michigan State University</institution>
            <addr-line>404 Wilson Rd</addr-line>
            <addr-line>East Lansing, MI, 48824</addr-line>
            <country>United States</country>
            <phone>1 517 432 5192</phone>
            <email>camposca@msu.edu</email>
          </address>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-7376-1842</ext-link>
        </contrib>
        <contrib id="contrib2" contrib-type="author">
          <name name-style="western">
            <surname>Atkinson</surname>
            <given-names>Elise</given-names>
          </name>
          <degrees>BS</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0009-0009-9197-898X</ext-link>
        </contrib>
        <contrib id="contrib3" contrib-type="author">
          <name name-style="western">
            <surname>Nishii</surname>
            <given-names>Uta</given-names>
          </name>
          <degrees>BS</degrees>
          <xref rid="aff2" ref-type="aff">2</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0009-0000-4472-4631</ext-link>
        </contrib>
      </contrib-group>
      <aff id="aff1">
        <label>1</label>
        <institution>Department of Media and Information</institution>
        <institution>Michigan State University</institution>
        <addr-line>East Lansing, MI</addr-line>
        <country>United States</country>
      </aff>
      <aff id="aff2">
        <label>2</label>
        <institution>Department of Statistics and Probability</institution>
        <institution>Michigan State University</institution>
        <addr-line>East Lansing, MI</addr-line>
        <country>United States</country>
      </aff>
      <author-notes>
        <corresp>Corresponding Author: Celeste Campos-Castillo <email>camposca@msu.edu</email></corresp>
      </author-notes>
      <pub-date pub-type="collection">
        <year>2025</year>
      </pub-date>
      <pub-date pub-type="epub">
        <day>8</day>
        <month>9</month>
        <year>2025</year>
      </pub-date>
      <volume>27</volume>
      <elocation-id>e59976</elocation-id>
      <history>
        <date date-type="received">
          <day>27</day>
          <month>4</month>
          <year>2024</year>
        </date>
        <date date-type="rev-request">
          <day>15</day>
          <month>8</month>
          <year>2024</year>
        </date>
        <date date-type="rev-recd">
          <day>12</day>
          <month>10</month>
          <year>2024</year>
        </date>
        <date date-type="accepted">
          <day>29</day>
          <month>10</month>
          <year>2024</year>
        </date>
      </history>
      <copyright-statement>©Celeste Campos-Castillo, Elise Atkinson, Uta Nishii. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 08.09.2025.</copyright-statement>
      <copyright-year>2025</copyright-year>
      <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
        <p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Journal of Medical Internet Research (ISSN 1438-8871), is properly cited. The complete bibliographic information, a link to the original publication on https://www.jmir.org/, as well as this copyright and license information must be included.</p>
      </license>
      <self-uri xlink:href="https://www.jmir.org/2025/1/e59976" xlink:type="simple"/>
      <abstract>
        <p>We estimated linear mixed-effects models to analyze changes in language patterns (as measured using Linguistic Inquiry and Word Count) among neurodiverse youth to introduce a novel assessment useful for research into the potential benefits of special interests while minimizing respondent and researcher burden.</p>
      </abstract>
      <kwd-group>
        <kwd>online learning</kwd>
        <kwd>e-learning</kwd>
        <kwd>virtual learning</kwd>
        <kwd>text analysis</kwd>
        <kwd>focused interests</kwd>
        <kwd>circumscribed interests</kwd>
        <kwd>repetitive behaviors</kwd>
        <kwd>autism</kwd>
        <kwd>ADHD</kwd>
        <kwd>art therapy</kwd>
        <kwd>special education</kwd>
        <kwd>life skills</kwd>
        <kwd>neurodiverse</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec sec-type="introduction">
      <title>Introduction</title>
      <p>Special interests (SPINs) are circumscribed interests that may interfere with learning and socialization among neurodiverse youth [<xref ref-type="bibr" rid="ref1">1</xref>-<xref ref-type="bibr" rid="ref3">3</xref>]. Research has shifted to identify how SPINs can benefit neurodiverse youth [<xref ref-type="bibr" rid="ref1">1</xref>,<xref ref-type="bibr" rid="ref4">4</xref>-<xref ref-type="bibr" rid="ref6">6</xref>] but relies on biased guardian or teacher reports [<xref ref-type="bibr" rid="ref4">4</xref>,<xref ref-type="bibr" rid="ref5">5</xref>]. We introduce a novel assessment that analyzes the speaking turns of neurodiverse youth during an observational study where they cocreated SPIN-related artwork with mentors. To characterize language patterns, we used Linguistic Inquiry and Word Count (LIWC-22, Pennebaker Conglomerates, Inc) [<xref ref-type="bibr" rid="ref7">7</xref>], which has been used to automate the analysis of spoken words from neurodiverse populations [<xref ref-type="bibr" rid="ref8">8</xref>,<xref ref-type="bibr" rid="ref9">9</xref>]. Through examining how language patterns change when mentors engage SPINs, we demonstrate how SPINs may be advantageous while reducing respondent and researcher burden.</p>
    </sec>
    <sec sec-type="methods">
      <title>Methods</title>
      <sec>
        <title>Ethical Considerations</title>
        <p>The institutional review board of the University of Wisconsin-Milwaukee granted ethics approval (approval number 22.304). Written consent and assent were collected using a web-based form. Data were deidentified by assigning a pseudonym to participants. Participants were compensated with US $20.</p>
      </sec>
      <sec>
        <title>Overview</title>
        <p>A convenience sample of neurodiverse youth whose traits were consistent with level 1 (requiring support) or 2 (requiring substantial support) autism diagnoses [<xref ref-type="bibr" rid="ref10">10</xref>] participated in five weekly 75-minute Zoom (Zoom Communications) sessions [<xref ref-type="bibr" rid="ref11">11</xref>]. Each session started with an icebreaker in the main room (5 minutes); the student-mentor dyads then entered breakout rooms to cocreate digital artwork using Blender (Blender Foundation), Photoshop (Adobe), or Procreate (Savage Interactive; 60 minutes); and finally everyone returned to the main room to screenshare artwork (10 minutes). Mentors were advised to engage their student’s SPIN to build rapport and brainstorm the artwork’s topic. Because SPIN engagement was not required, it produced variation.</p>
        <p>A total of 9 neurodiverse youths participated (aged 10-25 years; sex: n=8 male, n=1 female; race: n=9 White). Each student was recorded at least once via Zoom, yielding 30 student sessions. The reasons for not recording were technical malfunction, absence, and lacking consent. The researcher turned off their video to minimize disturbance.</p>
        <p><xref ref-type="supplementary-material" rid="app1">Multimedia Appendix 1</xref> describes the transcript-processing to separate students’ speaking turns. Using LIWC-22, we examined word count and four linguistic categories: achievement (goal orientation), positive and negative emotion, and cognitive processing (active thinking). Scores for each category represent the percentage of words spoken that match words for that category (range 0-100). To determine whether the mentor engaged the student’s SPIN, the first two authors coded sessions independently (κ=0.83) and collectively made final determinations. The observed strategies were asking the student about the SPIN, asking the student to share other SPIN-related artwork, and participating in drawing SPIN-related artwork.</p>
        <p>For each language pattern, we estimated two linear mixed-effects models to identify students’ language patterns over the five sessions and changes associated with engaging with SPINs. In both, the fixed effects were student identifiers (1-9) and session numbers (1-5); the random effects were student identifiers. The second models added a fixed effect for whether a mentor engaged the SPIN in the student-session (yes/no), which were interacted with the fixed effects for session numbers. Mentors always engaged the SPIN in the first session, creating collinearity, thus the models in the second session (n=26) exclude these. Stata 18.1 (StataCorp) was used for the analysis, with a statistical significance set at .05 (2-tailed).</p>
      </sec>
    </sec>
    <sec sec-type="results">
      <title>Results</title>
      <p>The mean word count was 675.3 (SD 783.3). The means for achievement (1.1, SD 1.5), cognitive processing (10.0, SD 4.9), positive emotion (1.8, SD 3.3), and negative emotion (0.1, SD 0.3) were on the lower ranges. Table S1 in <xref ref-type="supplementary-material" rid="app1">Multimedia Appendix 1</xref> shows excerpts from student sessions that scored high and low.</p>
      <p>Tables S2 and S3 in <xref ref-type="supplementary-material" rid="app1">Multimedia Appendix 1</xref> show coefficients for the linear mixed-effects models. Based on the first set of models, <xref rid="figure1" ref-type="fig">Figure 1</xref> shows that scores, excluding word count, were significantly higher in the third session versus the first. Based on the second set of models, <xref rid="figure2" ref-type="fig">Figure 2</xref> shows that engaging SPINs was associated with increased achievement and emotion (positive, negative) scores during the third session but decreased scores for cognitive processing in all but the third. Table S1 in <xref ref-type="supplementary-material" rid="app1">Multimedia Appendix 1</xref> shows excerpts from the third session, specifically “Gerardo” celebrating achievements with a song and “Kaya” expressing concern over a setback.</p>
      <fig id="figure1" position="float">
        <label>Figure 1</label>
        <caption>
          <p>Predicted word count and category scores with 95% CIs by session number among neurodiverse youth in observational study.</p>
        </caption>
        <graphic xlink:href="jmir_v27i1e59976_fig1.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
      </fig>
      <fig id="figure2" position="float">
        <label>Figure 2</label>
        <caption>
          <p>Changes (with 95% CI) in word count and category scores attributable to special interest engagement among neurodiverse youth in observational study.</p>
        </caption>
        <graphic xlink:href="jmir_v27i1e59976_fig2.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
      </fig>
    </sec>
    <sec sec-type="discussion">
      <title>Discussion</title>
      <p>Words reflecting emotion and achievement were spoken more when mentors engaged with SPINs, which aligns with research indicating that SPINs can enhance social communication and learning but typically rely on guardian or teacher reports [<xref ref-type="bibr" rid="ref4">4</xref>-<xref ref-type="bibr" rid="ref6">6</xref>]. Using LIWC to analyze language patterns could reduce respondent and researcher burden while advancing research on SPINs.</p>
      <p>Limitations include a small homogenous sample and being unable to compare long-term influences of different strategies to engage students’ SPINs (each mentor used only one). Perhaps asking about the SPIN enhances the word count (ie, speaking more) compared to other strategies. Future observational research with larger, more diverse samples would enable identifying differential impacts.</p>
    </sec>
  </body>
  <back>
    <app-group>
      <supplementary-material id="app1">
        <label>Multimedia Appendix 1</label>
        <p>Description of transcript processing, excerpts from transcripts, and estimated coefficients in linear mixed-effects models.</p>
        <media xlink:href="jmir_v27i1e59976_app1.docx" xlink:title="DOCX File , 26 KB"/>
      </supplementary-material>
    </app-group>
    <glossary>
      <title>Abbreviations</title>
      <def-list>
        <def-item>
          <term id="abb1">SPIN</term>
          <def>
            <p>special interest</p>
          </def>
        </def-item>
      </def-list>
    </glossary>
    <ack>
      <p>The authors received funding from the College of Communication Arts and Sciences at Michigan State University and the National Endowment for the Arts (award number 1891727-38-22).</p>
    </ack>
    <notes>
      <sec>
        <title>Data Availability</title>
        <p>Ethical restrictions limit making the videos and transcripts publicly available because participants did not consent to their videos being shared and only consented to have their transcripts shared after the final report to the National Endowment for the Arts. Requests to access deidentified transcripts may be sent to irbinfo@uwm.edu.</p>
      </sec>
    </notes>
    <fn-group>
      <fn fn-type="conflict">
        <p>None declared.</p>
      </fn>
    </fn-group>
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