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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JMIR</journal-id>
      <journal-id journal-id-type="nlm-ta">J Med Internet Res</journal-id>
      <journal-title>Journal of Medical Internet Research</journal-title>
      <issn pub-type="epub">1438-8871</issn>
      <publisher>
        <publisher-name>JMIR Publications</publisher-name>
        <publisher-loc>Toronto, Canada</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">v26i1e60879</article-id>
      <article-id pub-id-type="pmid">39693140</article-id>
      <article-id pub-id-type="doi">10.2196/60879</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Original Paper</subject>
        </subj-group>
        <subj-group subj-group-type="article-type">
          <subject>Original Paper</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>A Digital Approach for Addressing Suicidal Ideation and Behaviors in Youth Mental Health Services: Observational Study</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="editor">
          <name>
            <surname>de Azevedo Cardoso</surname>
            <given-names>Taiane</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Astha</surname>
            <given-names>Varuna</given-names>
          </name>
        </contrib>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Sinha</surname>
            <given-names>Urjoshi</given-names>
          </name>
        </contrib>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Safa</surname>
            <given-names>Ramin</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib id="contrib1" contrib-type="author" corresp="yes">
          <name name-style="western">
            <surname>Chong</surname>
            <given-names>Min K</given-names>
          </name>
          <degrees>BSc (Hons)</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <address>
            <institution>Brain and Mind Centre</institution>
            <institution>The University of Sydney</institution>
            <addr-line>94 Mallett Street</addr-line>
            <addr-line>Camperdown, 2050</addr-line>
            <country>Australia</country>
            <phone>61 (02) 9114 2199</phone>
            <email>min.chong@sydney.edu.au</email>
          </address>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0003-4562-731X</ext-link>
        </contrib>
        <contrib id="contrib2" contrib-type="author">
          <name name-style="western">
            <surname>Hickie</surname>
            <given-names>Ian B</given-names>
          </name>
          <degrees>AM, MD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0001-8832-9895</ext-link>
        </contrib>
        <contrib id="contrib3" contrib-type="author">
          <name name-style="western">
            <surname>Ottavio</surname>
            <given-names>Antonia</given-names>
          </name>
          <degrees>Grad Dip, MCSL</degrees>
          <xref rid="aff2" ref-type="aff">2</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0001-8307-6200</ext-link>
        </contrib>
        <contrib id="contrib4" contrib-type="author">
          <name name-style="western">
            <surname>Rogers</surname>
            <given-names>David</given-names>
          </name>
          <degrees>BSN</degrees>
          <xref rid="aff3" ref-type="aff">3</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0009-0007-9884-4242</ext-link>
        </contrib>
        <contrib id="contrib5" contrib-type="author">
          <name name-style="western">
            <surname>Dimitropoulos</surname>
            <given-names>Gina</given-names>
          </name>
          <degrees>MSW, PhD, RSW, RMFT</degrees>
          <xref rid="aff4" ref-type="aff">4</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0001-9487-0290</ext-link>
        </contrib>
        <contrib id="contrib6" contrib-type="author">
          <name name-style="western">
            <surname>LaMonica</surname>
            <given-names>Haley M</given-names>
          </name>
          <degrees>BSc, MA, PhD, ABPP-CN</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-6563-5467</ext-link>
        </contrib>
        <contrib id="contrib7" contrib-type="author">
          <name name-style="western">
            <surname>Borgnolo</surname>
            <given-names>Luke J</given-names>
          </name>
          <degrees>BPsych (Hons)</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0009-0004-8221-2783</ext-link>
        </contrib>
        <contrib id="contrib8" contrib-type="author">
          <name name-style="western">
            <surname>McKenna</surname>
            <given-names>Sarah</given-names>
          </name>
          <degrees>BSc, BA, PhD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-8560-6399</ext-link>
        </contrib>
        <contrib id="contrib9" contrib-type="author">
          <name name-style="western">
            <surname>Scott</surname>
            <given-names>Elizabeth M</given-names>
          </name>
          <degrees>MD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <xref rid="aff5" ref-type="aff">5</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0003-3907-0324</ext-link>
        </contrib>
        <contrib id="contrib10" contrib-type="author">
          <name name-style="western">
            <surname>Iorfino</surname>
            <given-names>Frank</given-names>
          </name>
          <degrees>MBMSc, PhD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0003-1109-0972</ext-link>
        </contrib>
      </contrib-group>
      <aff id="aff1">
        <label>1</label>
        <institution>Brain and Mind Centre</institution>
        <institution>The University of Sydney</institution>
        <addr-line>Camperdown</addr-line>
        <country>Australia</country>
      </aff>
      <aff id="aff2">
        <label>2</label>
        <institution>headspace Bondi Junction</institution>
        <addr-line>Sydney</addr-line>
        <country>Australia</country>
      </aff>
      <aff id="aff3">
        <label>3</label>
        <institution>headspace Port Macquarie Youth Services</institution>
        <addr-line>Port Macquarie</addr-line>
        <country>Australia</country>
      </aff>
      <aff id="aff4">
        <label>4</label>
        <institution>Faculty of Social Work</institution>
        <institution>University of Calgary</institution>
        <addr-line>Calgary, AB</addr-line>
        <country>Canada</country>
      </aff>
      <aff id="aff5">
        <label>5</label>
        <institution>School of Medicine</institution>
        <institution>University of Notre Dame</institution>
        <addr-line>Sydney</addr-line>
        <country>Australia</country>
      </aff>
      <author-notes>
        <corresp>Corresponding Author: Min K Chong <email>min.chong@sydney.edu.au</email></corresp>
      </author-notes>
      <pub-date pub-type="collection">
        <year>2024</year>
      </pub-date>
      <pub-date pub-type="epub">
        <day>18</day>
        <month>12</month>
        <year>2024</year>
      </pub-date>
      <volume>26</volume>
      <elocation-id>e60879</elocation-id>
      <history>
        <date date-type="received">
          <day>27</day>
          <month>5</month>
          <year>2024</year>
        </date>
        <date date-type="rev-request">
          <day>6</day>
          <month>8</month>
          <year>2024</year>
        </date>
        <date date-type="rev-recd">
          <day>23</day>
          <month>8</month>
          <year>2024</year>
        </date>
        <date date-type="accepted">
          <day>25</day>
          <month>9</month>
          <year>2024</year>
        </date>
      </history>
      <copyright-statement>©Min K Chong, Ian B Hickie, Antonia Ottavio, David Rogers, Gina Dimitropoulos, Haley M LaMonica, Luke J Borgnolo, Sarah McKenna, Elizabeth M Scott, Frank Iorfino. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 18.12.2024.</copyright-statement>
      <copyright-year>2024</copyright-year>
      <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
        <p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Journal of Medical Internet Research (ISSN 1438-8871), is properly cited. The complete bibliographic information, a link to the original publication on https://www.jmir.org/, as well as this copyright and license information must be included.</p>
      </license>
      <self-uri xlink:href="https://www.jmir.org/2024/1/e60879" xlink:type="simple"/>
      <abstract>
        <sec sec-type="background">
          <title>Background</title>
          <p>Long wait times for mental health treatments may cause delays in early detection and management of suicidal ideation and behaviors, which are crucial for effective mental health care and suicide prevention. The use of digital technology is a potential solution for prompt identification of youth with high suicidality.</p>
        </sec>
        <sec sec-type="objective">
          <title>Objective</title>
          <p>The primary aim of this study was to evaluate the use of a digital suicidality notification system designed to detect and respond to suicidal needs in youth mental health services. Second, the study aimed to characterize young people at different levels of suicidal ideation and behaviors.</p>
        </sec>
        <sec sec-type="methods">
          <title>Methods</title>
          <p>Young people aged between 16 and 25 years completed multidimensional assessments using a digital platform, collecting demographic, clinical, social, functional, and suicidality information. When the suicidality score exceeded a predetermined threshold, established based on clinical expertise and service policies, a rule-based algorithm configured within the platform immediately generated an alert for treating clinicians. Subsequent clinical actions and response times were analyzed.</p>
        </sec>
        <sec sec-type="results">
          <title>Results</title>
          <p>A total of 2021 individuals participated, of whom 266 (11%) triggered one or more high suicidal ideation and behaviors notification. Of the 292 notifications generated, 76% (222/292) were resolved, with a median response time of 1.9 (range 0-50.8) days. Clinical actions initiated to address suicidality included creating safety plans (60%, 134/222), conducting safety checks (18%, 39/222), psychological therapy (8%, 17/222), transfer to another service (3%, 8/222), and scheduling of new appointments (2%, 4/222). Young people with high levels of suicidality were more likely to present with more severe and comorbid symptoms, including low engagement in work or education, heterogenous psychopathology, substance misuse, and recurrent illness.</p>
        </sec>
        <sec sec-type="conclusions">
          <title>Conclusions</title>
          <p>The digital suicidality notification system facilitated prompt clinical actions by alerting clinicians to high levels of suicidal ideation and behaviors detected among youth. Further, the multidimensional assessment revealed complex and comorbid symptoms exhibited in youth with high suicidality. By expediting and personalizing care for those displaying elevated suicidality, the digital notification system can play a pivotal role in preventing rapid symptom progression and its detrimental impacts on young people’s mental health.</p>
        </sec>
      </abstract>
      <kwd-group>
        <kwd>mental health service</kwd>
        <kwd>youth mental health</kwd>
        <kwd>suicide management</kwd>
        <kwd>clinical decision support</kwd>
        <kwd>primary care</kwd>
        <kwd>personalization</kwd>
        <kwd>suicide</kwd>
        <kwd>suicidal</kwd>
        <kwd>youth</kwd>
        <kwd>mental health</kwd>
        <kwd>mental health care</kwd>
        <kwd>suicide prevention</kwd>
        <kwd>digital technology</kwd>
        <kwd>online assessment</kwd>
        <kwd>clinician</kwd>
        <kwd>digital health</kwd>
        <kwd>health informatics</kwd>
        <kwd>clinical information</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec sec-type="introduction">
      <title>Introduction</title>
      <p>The high prevalence of suicidal ideation and behaviors among youth is alarming [<xref ref-type="bibr" rid="ref1">1</xref>]. While the biological and psychosocial factors associated with the development of suicidality are complex [<xref ref-type="bibr" rid="ref2">2</xref>] and alone cannot predict the risk of suicide, it is strongly associated with long-term severe mental illnesses [<xref ref-type="bibr" rid="ref3">3</xref>], poor social functioning, [<xref ref-type="bibr" rid="ref1">1</xref>], and future suicidal behaviors [<xref ref-type="bibr" rid="ref4">4</xref>,<xref ref-type="bibr" rid="ref5">5</xref>]. Therefore, effective identification and management of suicidality in youth mental health services is crucial for detecting individuals with complex needs and preventing further progression of symptoms [<xref ref-type="bibr" rid="ref6">6</xref>,<xref ref-type="bibr" rid="ref7">7</xref>].</p>
      <p>Conducting a thorough and efficient assessment of suicidality poses time and labor constraints on services with high demand [<xref ref-type="bibr" rid="ref8">8</xref>]. Such barriers often lead to delays in screening, timely responses, and the delivery of appropriate interventions. Extended wait times can be especially unsafe for young people experiencing intense levels of suicidal ideation and behaviors [<xref ref-type="bibr" rid="ref9">9</xref>,<xref ref-type="bibr" rid="ref10">10</xref>].</p>
      <p>Digital technology is a potential solution for operationalizing timely assessments in mental health services [<xref ref-type="bibr" rid="ref7">7</xref>]. Further, a digital notification system that can alert severe or sudden changes in a client’s mental health symptoms can facilitate prompt care coordination and allocation. The clinical use and feasibility of such systems have been generally well-accepted in other areas of medicine [<xref ref-type="bibr" rid="ref11">11</xref>-<xref ref-type="bibr" rid="ref13">13</xref>].</p>
      <p>In 2017, a digital notification system that detects suicidal ideation and behaviors in youth mental health services was developed and evaluated [<xref ref-type="bibr" rid="ref14">14</xref>]. This pilot study demonstrated its effectiveness for triaging young people with high levels of suicidality into appropriate care in large general practitioner practices and youth mental health services [<xref ref-type="bibr" rid="ref14">14</xref>,<xref ref-type="bibr" rid="ref15">15</xref>]. However, the longitudinal feasibility of this system has not yet been explored.</p>
      <p>Therefore, this study aims to evaluate the use of a digital suicidality notification system in youth mental health services over a 5-year period in a naturalistic setting. The current study reports the rate and type of clinical responses initiated by suicidality notifications and identifies the clinical, social, and functional needs of young people at different levels of suicidality.</p>
    </sec>
    <sec sec-type="methods">
      <title>Methods</title>
      <sec>
        <title>Recruitment</title>
        <p>Young people aged between 16 and 25 years, who presented to primary (headspace [<xref ref-type="bibr" rid="ref16">16</xref>]) and community mental health services between November 2018 and October 2023 were invited to participate. All young people who were within the age range and used a digital platform, Innowell (University of Sydney and PwC), were eligible to participate in this study.</p>
      </sec>
      <sec>
        <title>Participant Procedures</title>
        <p>All participants filled out self-reported, multidimensional assessments before their initial consultation as part of the intake process at participating services. After the mandatory initial assessment, reassessment was encouraged for symptom monitoring throughout care. The questionnaire was administered through the Innowell platform, a web-based platform that supports individuals’ mental health by facilitating regular symptom monitoring, and client-clinician feedback [<xref ref-type="bibr" rid="ref17">17</xref>].</p>
        <p>The multidimensional assessments collected demographics, mental health (eg, depressive, anxiety, mania, psychosis, and eating disorder symptoms), suicidal thoughts and behaviors, social and occupational functioning (eg, education, employment, and social connectedness), and substance use information of participants. A detailed description of the assessments is provided in <xref ref-type="supplementary-material" rid="app1">Multimedia Appendix 1</xref>.</p>
      </sec>
      <sec>
        <title>Measures for Suicidal Thoughts and Behaviors</title>
        <p>Suicidal ideation and behaviors were assessed using 2 self-reported measures. Suicidal ideation over the past month was measured using the Suicidal Ideation Attributes Scale (SIDAS, [<xref ref-type="bibr" rid="ref18">18</xref>]). This scale is comprised of 5 items, assessing the frequency of suicidal thoughts, the individual’s ability to control these thoughts and closeness of attempting a suicide, related distress, and the extent of their impact on performing daily tasks. Each item was rated using a 10-point Likert scale where a higher value indicated more severe suicidal ideation. The SIDAS has been validated in an online survey of community-based Australian adults [<xref ref-type="bibr" rid="ref18">18</xref>]. In addition, the Columbia-Suicide Severity Rating Scale (C-SSRS, [<xref ref-type="bibr" rid="ref19">19</xref>]) examined suicide intent and planning over the past month and the history of suicidal attempts in the lifetime. The internal validity and consistency of C-SSRS have been validated in a multisite study with adolescents and adults [<xref ref-type="bibr" rid="ref19">19</xref>].</p>
      </sec>
      <sec>
        <title>Digital Suicidality Notification System</title>
        <p>The digital suicidality notification system is a configurable system embedded in the Innowell platform. When a young person completes the SIDAS and C-SSRS assessments, the system categorizes them into no, low, and high suicidality groups based on their results (<xref rid="figure1" ref-type="fig">Figure 1</xref>A). Then the system triggers appropriate actions based on their suicidality group. Thresholds for different levels of suicidality were developed by expert psychiatrists (IBH and EMS) and adjusted to existing suicidal risk management policies at services when necessary (development and thresholds of suicidality levels are provided in <xref ref-type="supplementary-material" rid="app2">Multimedia Appendix 2</xref>).</p>
        <fig id="figure1" position="float">
          <label>Figure 1</label>
          <caption>
            <p>Workflow of the digital suicidality notification system.</p>
          </caption>
          <graphic xlink:href="jmir_v26i1e60879_fig1.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
        </fig>
        <p>After categorization, participants in low or high suicidality groups immediately receive a pop-up message with contact information for 24-hour crisis support services, such as Lifeline, Kids Helpline, and Mental Health Helpline. For individuals in the high suicidality group, the system also sends an automatic notification to treating clinicians, prompting immediate clinical actions. This notification appears as a red triangle next to the person’s name on the clinicians’ Innowell dashboard (<xref rid="figure1" ref-type="fig">Figure 1</xref>B).</p>
        <p>Clinicians can resolve the notification by logging clinical actions taken in response to the suicidality detected. There are 4 available options, which are “assigned a care option,” “transferred to another service,” “unable to contact,” or “other.” Under “assigned a care option,” clinicians could further specify their clinical action by selecting one of the options provided on Innowell: “safety plan,” “safety check,” “psychological intervention,” “scheduling a new appointment,” or “other.” Resolving the notification removes the red triangle (<xref rid="figure1" ref-type="fig">Figure 1</xref>C).</p>
        <p>It was not mandatory for services to resolve these notifications. Instead, the research team recommended managing notifications according to the services’ own safety and governance protocol. This flexible adaptation approach was taken for smooth integration of the system into existing clinical workflows.</p>
        <p>Further, participants were provided with clear expectations regarding how notifications would be responded to. During onboarding, they were informed about how the data collected would be used by services, and the international standard data privacy and security measures in place to ensure data safety. Staff communicated that these services did not provide 24-hour crisis support and that the platform would only be monitored during clinical hours (eg, Monday to Friday 8 AM to 5 PM). However, automated pop-up messages provided information on external crisis resources at all times.</p>
      </sec>
      <sec>
        <title>Statistical Analysis</title>
        <p>All statistical analyses were performed using R (version 4.3.1; R Core Team). In total, 3 pairwise comparisons were conducted between the suicidality groups: (1) no versus low suicidality, (2) low versus high suicidality, and (3) no versus high suicidality. Chi-square tests were used for categorical variables and Kruskal-Wallis tests were used for continuous variables. Post hoc pairwise comparisons were performed using Dunn tests, with a Bonferroni correction applied to address the 3 comparisons made for each variable and to counteract the family-wise error rate (<italic>P</italic>&lt;.02). Analyses were performed with complete observations for each variable and missing values were regarded as missing at random.</p>
        <p>In addition, an opinion statement was provided by coauthors, who are service staff from the participating services, to reflect on their experiences of using the digital notification system in youth mental health services.</p>
      </sec>
      <sec>
        <title>Ethical Consideration</title>
        <p>The Northern Sydney Local Health District Human Research Ethics Committees approved this study (HREC/17/HAWKE/480), and all participants gave online informed consent (through an opt-out process). In addition, to ensure confidentiality and privacy of participant information, all data stored in the research database were deidentified and could only be accessed by researchers in this study for research purposes.</p>
      </sec>
    </sec>
    <sec sec-type="results">
      <title>Results</title>
      <sec>
        <title>Sample Characteristics</title>
        <p>A total of 2021 young people completed the intake multidimensional assessment, and 226 (11%) individuals triggered a high suicidality notification. The mean age of the cohort was 20.2 (SD 2.6) years and 72% (1463/2021) were female. Approximately a quarter of participants were receiving government benefits (26%, 523/2021), and two-thirds reported that they could not independently support themselves (67%, 1361/2021). One-tenth of individuals were not in employment, education, or training (NEET; 11%, 211/1902). On average, participants reported that they were out of work for 7.4 days (SD 7.9) out of the past 30 days. Further information on demographic, clinical, social, and functional characteristics of participants has been provided in <xref ref-type="table" rid="table1">Table 1</xref>.</p>
        <table-wrap position="float" id="table1">
          <label>Table 1</label>
          <caption>
            <p>Baseline characteristics of participants and comparisons between different levels of suicidality.</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="30"/>
            <col width="200"/>
            <col width="130"/>
            <col width="130"/>
            <col width="130"/>
            <col width="0"/>
            <col width="100"/>
            <col width="100"/>
            <col width="100"/>
            <col width="0"/>
            <col width="0"/>
            <col width="80"/>
            <thead>
              <tr valign="top">
                <td colspan="2">
                  <break/>
                </td>
                <td>No suicidality</td>
                <td>Low suicidality</td>
                <td>High suicidality</td>
                <td colspan="2">No versus low, <italic>P</italic> value</td>
                <td>Low versus high, <italic>P</italic> value</td>
                <td>No versus high, <italic>P</italic> value</td>
                <td colspan="3">Missing values, n</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td colspan="2">Participants, n (%)</td>
                <td>1002 (50)</td>
                <td>793 (39)</td>
                <td>226 (11)</td>
                <td colspan="2">—<sup>a</sup></td>
                <td>—</td>
                <td>—</td>
                <td colspan="3">—</td>
              </tr>
              <tr valign="top">
                <td colspan="2">Mean age (years), (SD)</td>
                <td>20 (2.5)</td>
                <td>20.5 (2.6)</td>
                <td>19.8 (2.6)</td>
                <td colspan="2">&lt;.001</td>
                <td>&lt;.001</td>
                <td>—</td>
                <td colspan="3">—</td>
              </tr>
              <tr valign="top">
                <td colspan="2">Females, n (%)</td>
                <td>710 (71)</td>
                <td>593 (75)</td>
                <td>160 (71)</td>
                <td colspan="2">—</td>
                <td>—</td>
                <td>—</td>
                <td colspan="3">—</td>
              </tr>
              <tr valign="top">
                <td colspan="2">With disability, n (%)</td>
                <td>50 (5)</td>
                <td>86 (11)</td>
                <td>25 (11)</td>
                <td colspan="2">&lt;.001</td>
                <td>—</td>
                <td>.01</td>
                <td colspan="3">—</td>
              </tr>
              <tr valign="top">
                <td colspan="2">English speaking, n (%)</td>
                <td>925 (92)</td>
                <td>738 (93)</td>
                <td>200 (89)</td>
                <td colspan="2">—</td>
                <td>—</td>
                <td>—</td>
                <td colspan="3">—</td>
              </tr>
              <tr valign="top">
                <td colspan="2">Indigenous, n (%)</td>
                <td>51 (5)</td>
                <td>34 (4)</td>
                <td>11 (5)</td>
                <td colspan="2">—</td>
                <td>—</td>
                <td>—</td>
                <td colspan="3">—</td>
              </tr>
              <tr valign="top">
                <td colspan="2">Living alone, n (%)</td>
                <td>62 (6)</td>
                <td>74 (9)</td>
                <td>23 (10)</td>
                <td colspan="2">—</td>
                <td>—</td>
                <td>—</td>
                <td colspan="3">—</td>
              </tr>
              <tr valign="top">
                <td colspan="2">Single, n (%)</td>
                <td>613 (61)</td>
                <td>497 (63)</td>
                <td>152 (67)</td>
                <td colspan="2">—</td>
                <td>—</td>
                <td>—</td>
                <td colspan="3">—</td>
              </tr>
              <tr valign="top">
                <td colspan="11">
                  <bold>Education, n (%)</bold>
                </td>
                <td>8</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Secondary</td>
                <td>720 (72)</td>
                <td>531 (67)</td>
                <td>160 (71)</td>
                <td colspan="2">—</td>
                <td>—</td>
                <td>—</td>
                <td colspan="3">—</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Tertiary</td>
                <td>275 (27)</td>
                <td>261 (33)</td>
                <td>66 (29)</td>
                <td colspan="2">—</td>
                <td>—</td>
                <td>—</td>
                <td colspan="3">—</td>
              </tr>
              <tr valign="top">
                <td colspan="11">
                  <bold>Social and occupational function</bold>
                </td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>NEET<sup>b</sup>, n (%)</td>
                <td>117 (12)</td>
                <td>65 (8)</td>
                <td>29 (13)</td>
                <td colspan="2">—</td>
                <td>—</td>
                <td>—</td>
                <td colspan="3">119</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Days out of role in last 30 days, mean (SD)</td>
                <td>6.7 (7.8)</td>
                <td>7.3 (7.6)</td>
                <td>10.5 (8.9)</td>
                <td colspan="2">—</td>
                <td>&lt;.001</td>
                <td>&lt;.001</td>
                <td colspan="3">—</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Receiving government benefit, n (%)</td>
                <td>261 (26)</td>
                <td>202 (26)</td>
                <td>60 (27)</td>
                <td colspan="2">—</td>
                <td>—</td>
                <td>—</td>
                <td colspan="3">—</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Dependent support level, n (%)</td>
                <td>663 (66)</td>
                <td>536 (68)</td>
                <td>162 (72)</td>
                <td colspan="2">—</td>
                <td>—</td>
                <td>—</td>
                <td colspan="3">—</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td> Everyday functioning (WSAS)<sup>c</sup>, mean (SD)</td>
                <td>16.9 (8.5)</td>
                <td>19.2 (8.3)</td>
                <td>24.2 (8.0)</td>
                <td colspan="2">&lt;.001</td>
                <td>&lt;.001</td>
                <td>&lt;.001</td>
                <td colspan="3">81</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td> Social connectedness (SSSS)<sup>d</sup>, mean (SD)</td>
                <td>7.1 (3.4)</td>
                <td>7.2 (3.3)</td>
                <td>8.7 (3.8)</td>
                <td colspan="2">—</td>
                <td>&lt;.001</td>
                <td>&lt;.001</td>
                <td colspan="3">254</td>
              </tr>
              <tr valign="top">
                <td colspan="12">
                  <bold>Personal mental health history</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Any family mental health history, n (%)</td>
                <td>550 (55)</td>
                <td>471 (59)</td>
                <td>128 (57)</td>
                <td colspan="2">—</td>
                <td>—</td>
                <td>—</td>
                <td colspan="3">441</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Mental illness history, n (%)</td>
                <td>511 (51)</td>
                <td>566 (71)</td>
                <td>185 (82)</td>
                <td colspan="2">&lt;.001</td>
                <td>—</td>
                <td>&lt;.001</td>
                <td colspan="3">295</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Mental health-related hospitalization history, n (%)</td>
                <td>64 (6)</td>
                <td>132 (17)</td>
                <td>73 (32)</td>
                <td colspan="2">&lt;.001</td>
                <td>&lt;.001</td>
                <td>&lt;.001</td>
                <td colspan="3">295</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Sought prior treatment, n (%)</td>
                <td>542 (54)</td>
                <td>570 (72)</td>
                <td>170 (75)</td>
                <td colspan="2">&lt;.001</td>
                <td>—</td>
                <td>.001</td>
                <td colspan="3">293</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Age when first sought help (y), mean (SD)</td>
                <td>15.6 (3.6)</td>
                <td>15.4 (3.7)</td>
                <td>14.8 (3.9)</td>
                <td colspan="2">—</td>
                <td>—</td>
                <td>—</td>
                <td colspan="3">710</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Experienced traumatic event, n (%)</td>
                <td>350 (35)</td>
                <td>333 (42)</td>
                <td>107 (47)</td>
                <td colspan="2">—</td>
                <td>—</td>
                <td>—</td>
                <td colspan="3">388</td>
              </tr>
              <tr valign="top">
                <td colspan="12">
                  <bold>Physical comorbidity, n (%)</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Major physical illness</td>
                <td>255 (25)</td>
                <td>232 (29)</td>
                <td>64 (28)</td>
                <td colspan="2">—</td>
                <td>—</td>
                <td>—</td>
                <td colspan="3">388</td>
              </tr>
              <tr valign="top">
                <td colspan="12">
                  <bold>Clinical presentation, mean (SD)</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td> Psychological distress (K-10)<sup>e</sup></td>
                <td>29.9 (8.7)</td>
                <td>31.6 (8.4)</td>
                <td>36.1 (6.8)</td>
                <td colspan="2">&lt;.001</td>
                <td>&lt;.001</td>
                <td>&lt;.001</td>
                <td colspan="3">99</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td> Depression (QIDS)<sup>f</sup></td>
                <td>12.6 (5.2)</td>
                <td>14 (4.8)</td>
                <td>17.7 (4.5)</td>
                <td colspan="2">&lt;.001</td>
                <td>&lt;.001</td>
                <td>&lt;.001</td>
                <td colspan="3">304</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td> Anxiety (OASIS)<sup>g</sup></td>
                <td>8.8 (4.2)</td>
                <td>9.5 (4.1)</td>
                <td>11.5 (4.5)</td>
                <td colspan="2">&lt;.001</td>
                <td>&lt;.001</td>
                <td>&lt;.001</td>
                <td colspan="3">299</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td> Psychosis (PQ-16)<sup>h</sup></td>
                <td>4.6 (3.8)</td>
                <td>5 (3.5)</td>
                <td>6.6 (4.1)</td>
                <td colspan="2">.003</td>
                <td>&lt;.001</td>
                <td>&lt;.001</td>
                <td colspan="3">381</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td> Mania (ASRM)<sup>i</sup></td>
                <td>2.9 (2.9)</td>
                <td>3 (2.9)</td>
                <td>2.7 (2.7)</td>
                <td colspan="2">—</td>
                <td>—</td>
                <td>—</td>
                <td colspan="3">374</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td> Eating disorder (EDE-Q)<sup>j</sup></td>
                <td>4.5 (3.0)</td>
                <td>4.8 (3)</td>
                <td>5.5 (3.0)</td>
                <td colspan="2">—</td>
                <td>.001</td>
                <td>&lt;.001</td>
                <td colspan="3">349</td>
              </tr>
              <tr valign="top">
                <td colspan="12">
                  <bold>At-risk mental states, n (%)</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Mania-like experience</td>
                <td>169 (17)</td>
                <td>178 (22)</td>
                <td>47 (21)</td>
                <td colspan="2">&lt;.001</td>
                <td>—</td>
                <td>&lt;.001</td>
                <td colspan="3">374</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Psychosis-like experience</td>
                <td>269 (27)</td>
                <td>270 (34)</td>
                <td>100 (44)</td>
                <td colspan="2">&lt;.001</td>
                <td>—</td>
                <td>&lt;.001</td>
                <td colspan="3">—</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Circadian disturbance</td>
                <td>382 (38)</td>
                <td>359 (45)</td>
                <td>127 (56)</td>
                <td colspan="2">.003</td>
                <td>.005</td>
                <td>&lt;.001</td>
                <td colspan="3">349</td>
              </tr>
              <tr valign="top">
                <td colspan="12">
                  <bold>Suicidal thoughts and behaviors</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Self-harm history, n (%)</td>
                <td>341 (34)</td>
                <td>465 (59)</td>
                <td>159 (70)</td>
                <td colspan="2">&lt;.001</td>
                <td>.002</td>
                <td>&lt;.001</td>
                <td colspan="3">346</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td> Suicidal ideation (SIDAS)<sup>k</sup>, mean (SD)</td>
                <td>5.1 (9.5)</td>
                <td>9.3 (9)</td>
                <td>26 (12.4)</td>
                <td colspan="2">&lt;.001</td>
                <td>&lt;.001</td>
                <td>&lt;.001</td>
                <td colspan="3">179</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Prior suicide attempt, n (%)</td>
                <td>192 (19)</td>
                <td>369 (47)</td>
                <td>179 (79)</td>
                <td colspan="2">&lt;.001</td>
                <td>&lt;.001</td>
                <td>&lt;.001</td>
                <td colspan="3">216</td>
              </tr>
              <tr valign="top">
                <td colspan="12">
                  <bold>Alcohol and substance misuse, mean (SD)</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td> Alcohol (AUDIT-C)<sup>l</sup></td>
                <td>4.4 (2.3)</td>
                <td>4.6 (2.5)</td>
                <td>5.2 (2.6)</td>
                <td colspan="2">—</td>
                <td>—</td>
                <td>.005</td>
                <td colspan="3">699</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td> Cannabis (ASSIST)<sup>m</sup></td>
                <td>1.5 (2.8)</td>
                <td>1.8 (3.1)</td>
                <td>2.3 (3.4)</td>
                <td colspan="2">—</td>
                <td>.007</td>
                <td>&lt;.001</td>
                <td colspan="3">354</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Tobacco (ASSIST)</td>
                <td>1.3 (2.1)</td>
                <td>1.7 (2.3)</td>
                <td>2.2 (2.4)</td>
                <td colspan="2">.003</td>
                <td>&lt;.001</td>
                <td>&lt;.001</td>
                <td colspan="3">352</td>
              </tr>
            </tbody>
          </table>
          <table-wrap-foot>
            <fn id="table1fn1">
              <p><sup>a</sup>Not applicable.</p>
            </fn>
            <fn id="table1fn2">
              <p><sup>b</sup>NEET: not in education, employment, or training.</p>
            </fn>
            <fn id="table1fn3">
              <p><sup>c</sup>WSAS: Work and Social Adjustment Scale.</p>
            </fn>
            <fn id="table1fn4">
              <p><sup>d</sup>SSSS: Schuster’s Social Support Scale.</p>
            </fn>
            <fn id="table1fn5">
              <p><sup>e</sup>K-10: Kessler-10.</p>
            </fn>
            <fn id="table1fn6">
              <p><sup>f</sup>QIDS: Quick Inventory of Depressive Symptomatology.</p>
            </fn>
            <fn id="table1fn7">
              <p><sup>g</sup>OASIS: Overall Anxiety Severity and Impairment Scale.</p>
            </fn>
            <fn id="table1fn8">
              <p><sup>h</sup>PQ-16: Prodromal Questionnaire.</p>
            </fn>
            <fn id="table1fn9">
              <p><sup>i</sup>ASRM: Altman Self-Rating Mania Scale.</p>
            </fn>
            <fn id="table1fn10">
              <p><sup>j</sup>EDE-Q: Eating Behaviors and Body Image Questionnaire</p>
            </fn>
            <fn id="table1fn11">
              <p><sup>k</sup>SIDAS: Suicidal Ideation Attributes Scale.</p>
            </fn>
            <fn id="table1fn12">
              <p><sup>l</sup>AUDIT-C: Alcohol Use Disorders Identification Test.</p>
            </fn>
            <fn id="table1fn13">
              <p><sup>m</sup>ASSIST: Alcohol, Smoking and Substance Involvement Screening.</p>
            </fn>
          </table-wrap-foot>
        </table-wrap>
      </sec>
      <sec>
        <title>Real-Time Helpline Pop-Up, Notification, and Response Characteristics</title>
        <p>A total of 1828 helpline pop-up messages were generated, and 16% (292/1828) were accompanied by a real-time high suicidality notification. Out of the 292 notifications generated, 222 (76%) were resolved, and the median response time was 1.9 (range 0-50.8, mean 3.5, SD 5.4) days (<xref rid="figure2" ref-type="fig">Figure 2</xref>). Out of the 226 individuals who triggered a notification, 36 participants generated multiple notifications (mean 2.8, SD 1.4, range=2-6).</p>
        <fig id="figure2" position="float">
          <label>Figure 2</label>
          <caption>
            <p>Distribution of time taken to resolve high suicidality notifications. The dashed line indicates the median response time (median 1.9 days, IQR 0-50.8 days). Outliers have been excluded in this graph for readability.</p>
          </caption>
          <graphic xlink:href="jmir_v26i1e60879_fig2.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
        </fig>
        <p>Most notifications were resolved by building a safety plan (134/222, 60%), followed by performing a safety check (39/222, 18%), initiating psychological therapies (17/222, 8%), transferring to another service (8/222, 4%; eg, general practitioner), and scheduling a new appointment with a mental health professional (4/222, 2%). Services were unable to contact 9% of individuals (20/222, <xref ref-type="table" rid="table2">Table 2</xref>).</p>
        <table-wrap position="float" id="table2">
          <label>Table 2</label>
          <caption>
            <p>Clinical responses initiated to resolve high suicidality notifications.</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="500"/>
            <col width="500"/>
            <thead>
              <tr valign="top">
                <td>Clinical response</td>
                <td>Values, n (%)</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td>Safety plan</td>
                <td>134 (60)</td>
              </tr>
              <tr valign="top">
                <td>Safety check</td>
                <td>39 (18)</td>
              </tr>
              <tr valign="top">
                <td>Unable to contact</td>
                <td>20 (9)</td>
              </tr>
              <tr valign="top">
                <td>Psychological therapy</td>
                <td>17 (8)</td>
              </tr>
              <tr valign="top">
                <td>Transferred to another service</td>
                <td>8 (4)</td>
              </tr>
              <tr valign="top">
                <td>New appointment offered</td>
                <td>4 (2)</td>
              </tr>
            </tbody>
          </table>
        </table-wrap>
      </sec>
      <sec>
        <title>Differences in Clinical and Functional Characteristics Between Suicidality Groups</title>
        <p>Pairwise comparisons were conducted between no, low, and high suicidality groups (<xref ref-type="table" rid="table1">Table 1</xref>). The low suicidality group was older than the high suicidality group (<italic>z</italic> score=3.5; <italic>P</italic>&lt;.001) and no suicidality group (<italic>z</italic> score=4, <italic>P</italic>&lt;.001). Further, disability was more prevalent in the high (<italic>χ</italic><sup>2</sup><sub>1</sub>=10.8; <italic>P</italic>=.001) and low (<italic>χ</italic><sup>2</sup><sub>1</sub>=20.8; <italic>P</italic>&lt;.001) groups compared to the no suicidality group.</p>
        <p>Several significant differences were observed between different suicidality groups in the social and occupational functioning domains. While there were no significant differences in the NEET status between the suicidality groups, the high suicidality group spent more days out of role compared with low (<italic>z</italic> score=5; <italic>P</italic>&lt;.001) and no suicidality groups (<italic>z</italic> score=6.5, <italic>P</italic>&lt;.001) within the last 30 days. Similarly, the high suicidality group experienced more social disconnection compared with the low (<italic>z</italic> score=5.0; <italic>P</italic>&lt;.001) and no suicidality groups (<italic>z</italic> score=5.5; <italic>P</italic>&lt;.001). Also, everyday functioning was most impaired in the high suicidality group (no vs high: <italic>z</italic> score=11.1, <italic>P</italic>&lt;.001; low vs high: <italic>z</italic> score=7.3, <italic>P</italic>&lt;.001; no vs low: <italic>z</italic> score=5.6, <italic>P</italic>&lt;.001).</p>
        <p>History of mental illness was least frequently reported in the no suicidality group (no vs low: <italic>χ</italic><sup>2</sup><sub>1</sub>=48.1, <italic>P</italic>&lt;.001; no vs high: <italic>χ</italic><sup>2</sup><sub>1</sub>=38.4, <italic>P</italic>&lt;.001), as well as mental health-related hospitalization history (no vs low: <italic>χ</italic><sup>2</sup><sub>1</sub>=37, <italic>P</italic>&lt;.001; no vs high: <italic>χ</italic><sup>2</sup><sub>1</sub>=96.1, <italic>P</italic>&lt;.001; low vs high: <italic>χ</italic><sup>2</sup><sub>1</sub>=21.5, <italic>P</italic>&lt;.001), and previous help-seeking history (no vs low: <italic>χ</italic><sup>2</sup><sub>1</sub>=33.9, <italic>P</italic>&lt;.001; no vs high: <italic>χ</italic><sup>2</sup><sub>1</sub>=10.7, <italic>P</italic>&lt;.001) compared with 2 other groups. The severity of psychological distress, depressive, and anxiety symptoms increased in the order of no, low to high suicidality groups. However, only the high suicidality group had higher levels of eating disorder behaviors (no vs high: <italic>z</italic> score=4.5, <italic>P</italic>&lt;.001; low vs high: <italic>z</italic> score=3.2, <italic>P</italic>&lt;.001).</p>
        <p>The high suicidality group had the highest suicidal ideation compared with low (<italic>z</italic> score=13; <italic>P</italic>&lt;.001) and no suicidality groups (<italic>z</italic> score=22.5; <italic>P</italic>&lt;.001), more frequent history of self-harm (no vs high: <italic>χ</italic><sup>2</sup><sub>1</sub>=85.7, <italic>P</italic>&lt;.001; low vs high: <italic>χ</italic><sup>2</sup><sub>1</sub>=9.5, <italic>P</italic>=.002) and higher rates of previous suicide attempts (no vs high: <italic>χ</italic><sup>2</sup><sub>1</sub>=251, <italic>P</italic>&lt;.001; low vs high: <italic>χ</italic><sup>2</sup><sub>1</sub>=65.1, <italic>P</italic>&lt;.001).</p>
      </sec>
      <sec>
        <title>Reflections on the Digital Notification System in Youth Mental Health Services</title>
        <p>Two service managers at participating centers highlighted the strengths of using the digital notification system to manage suicidality in youth mental health services (<xref ref-type="boxed-text" rid="box1">Textbox 1</xref>). The key strengths identified were service triage and wait time management, client engagement, facilitation of online resource use, and clinical decision-making support.</p>
        <boxed-text id="box1" position="float">
          <title>Strengths of the digital notification system – insights from clinical practice.</title>
          <p>Service triage and wait time management</p>
          <list list-type="bullet">
            <list-item>
              <p>The system supports service triage by reducing wait times for young people with high suicidality, ensuring they receive care at the time of their need. The support of a digital system is especially helpful during periods of low staffing for maintaining the quality of care and responsiveness.</p>
            </list-item>
          </list>
          <p>Client engagement</p>
          <list list-type="bullet">
            <list-item>
              <p>Reviewing assessment results from the digital platform (Innowell) can start conversations for young people who might have not discussed their suicidality previously. However, achieving this requires a service-wide adoption of the digital technology. All service staff and clinicians need to understand and consistently use the platform throughout the client journey to maximize its potential as an engagement and communication tool.</p>
            </list-item>
          </list>
          <p>Facilitation of online resource use</p>
          <list list-type="bullet">
            <list-item>
              <p>Many young people are willing to engage in safety planning on the platform when guided by a clinician. This interaction not only helps to manage suicidality but also builds rapport and familiarizes young people with using the platform effectively.</p>
            </list-item>
          </list>
          <p>Clinical decision-making support</p>
          <list list-type="bullet">
            <list-item>
              <p>The care options provided on the digital platform offer guidance to clinicians, particularly those with limited experience to build confidence in addressing suicidality in young people.</p>
            </list-item>
          </list>
        </boxed-text>
      </sec>
    </sec>
    <sec sec-type="discussion">
      <title>Discussion</title>
      <sec>
        <title>Principal Results</title>
        <p>This study demonstrates that a digital suicidality notification system successfully initiated subsequent clinical responses for young people who expressed high suicidal ideation and behaviors. Of the high suicidality notifications, 76% (222/292) were resolved, and the median response time was 1.9 days (range 0-50.8 days). Building on its initial evaluation in 2017 [<xref ref-type="bibr" rid="ref11">11</xref>], the high rate of resolved notifications over a 5-year period suggests that the system was accepted and used in real-world clinical settings.</p>
        <p>Further, the study reveals the multidimensional and complex symptom presentations of young people with low or high suicidality levels. Compared with the no suicidality group, the low and high groups exhibited higher levels of clinical symptoms, more severe social and occupational impairments, and circadian disturbances. A history of mental health diagnosis and related hospitalization were more frequently reported in these groups.</p>
        <p>Together, this study demonstrates the effectiveness of the digital notification system to detect suicidal needs, reveal associated symptom complexity, and trigger appropriate responses in youth mental health services.</p>
      </sec>
      <sec>
        <title>Digital Systems for Rapid and Personalized Management of Suicidality</title>
        <p>This evaluation demonstrated the potential of the digital notification system to facilitate stratification and personalization of care. The results show that most young people who elicited a notification received evidence-based treatment, including brief interventions (ie, safety checks and safety plan [<xref ref-type="bibr" rid="ref20">20</xref>-<xref ref-type="bibr" rid="ref23">23</xref>]), and long-term psychological interventions [<xref ref-type="bibr" rid="ref24">24</xref>-<xref ref-type="bibr" rid="ref26">26</xref>]. Alternatively, the system facilitated care stratification by expediting existing appointments and initiating care coordination, such as service transfers. Such cascades of clinical actions would have been delayed without this system. Research indicates that reducing wait times for individuals with high levels of suicidality could be critical due to its strong associations with severe mental illnesses [<xref ref-type="bibr" rid="ref27">27</xref>], the risk of recurrence of suicidal behaviors [<xref ref-type="bibr" rid="ref28">28</xref>], and comorbidity [<xref ref-type="bibr" rid="ref29">29</xref>]. Further, there is a high likelihood that individuals present to health services before suicide [<xref ref-type="bibr" rid="ref30">30</xref>]. Therefore, expedited clinical responses facilitated by the system may help reduce suicide rates through early detection and proactive care [<xref ref-type="bibr" rid="ref5">5</xref>,<xref ref-type="bibr" rid="ref31">31</xref>]. Addressing broader clinical and psychosocial needs associated with suicidal thoughts and behaviors could mitigate severe outcomes, such as suicide attempts [<xref ref-type="bibr" rid="ref32">32</xref>]. and emergency department presentations [<xref ref-type="bibr" rid="ref33">33</xref>].</p>
        <p>While the tool led to appropriate clinical actions, a 2-day median response rate may raise concerns about its timeliness for supporting youth who are highly suicidal. However, it is important to recognize that these participating services did not provide 24-hour crisis support, and young people were informed about the system’s limited monitoring hours. A potential future use of this system could include automatic transfer of notification information to 24-hour crisis support services outside of service operating hours, to help young people receive immediate help.</p>
        <p>Another research direction of this notification system is its potential to be reconfigured to detect different combinations of symptoms that indicate the need for rapid intervention, including psychosis-like symptoms and severe social impairments. In addition, the system could be enhanced by embedding machine learning tools to detect intraindividual changes in symptom trajectories [<xref ref-type="bibr" rid="ref34">34</xref>,<xref ref-type="bibr" rid="ref35">35</xref>], screen complex symptom presentations [<xref ref-type="bibr" rid="ref36">36</xref>], or analyze linguistic patterns to detect suicidality based on user-created content [<xref ref-type="bibr" rid="ref37">37</xref>,<xref ref-type="bibr" rid="ref38">38</xref>]. Integrating these tools into the notification system could facilitate services to quickly understand young people’s needs and take subsequent actions. This can be done by either providing direct care or coordinating with services that can deliver the required treatments.</p>
      </sec>
      <sec>
        <title>Multidimensional Needs of Youth With High Suicidality</title>
        <p>Notably, this study highlights the concurrent multidimensional impairments found in individuals with high levels of suicidality. Those who triggered a notification exhibited greater clinical, social, and functional impairments compared to groups with lower suicidality. These findings align with previous suicide research, where mental illnesses [<xref ref-type="bibr" rid="ref39">39</xref>], psychosis-like experiences [<xref ref-type="bibr" rid="ref40">40</xref>], irregular sleep-wake cycles [<xref ref-type="bibr" rid="ref41">41</xref>], and eating disorders [<xref ref-type="bibr" rid="ref42">42</xref>] have been associated with an increased likelihood of a suicide attempt. In particular, the association between high suicidality and severe social and occupational impairments, such as more days out of work and greater social disconnection, supports the causal relationship between these factors previously proposed [<xref ref-type="bibr" rid="ref43">43</xref>-<xref ref-type="bibr" rid="ref46">46</xref>].</p>
        <p>These findings emphasize the importance of multidimensional assessments in addressing suicidality. Considering the recent critique of the marginally positive effect sizes of common suicide prevention interventions [<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref47">47</xref>], deploying multidimensional measures could improve the identification of individuals’ underlying mechanisms and support the formulation of personalized treatments. Digital platforms offer several advantages in this context, offering increased accessibility, privacy for clients to complete assessments, and reduced time and labor demand for services [<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref49">49</xref>].</p>
      </sec>
      <sec>
        <title>Implications in Youth Mental Health Services</title>
        <p>A successful integration of the notification system into service workflow is crucial to maximize its benefits, as outlined in <xref ref-type="boxed-text" rid="box1">Textbox 1</xref>. Key strategies to facilitate implementation are the integration of the digital platform into clinical governance and the designation of key individuals to monitor notifications.</p>
        <p>Integration of the digital system into clinical governance involves establishing organizational protocols that explicitly outline its use within the existing workflow. These protocols should be codesigned with clinicians and service staff and regularly reviewed to ensure acceptability and feasibility. Training sessions and modeling its use by senior clinicians can promote implementation by emphasizing its clinical utility [<xref ref-type="bibr" rid="ref50">50</xref>,<xref ref-type="bibr" rid="ref51">51</xref>]. Further, addressing common barriers such as data privacy concerns through transparent communication of data confidentiality would be critical for building trust in the system [<xref ref-type="bibr" rid="ref52">52</xref>].</p>
        <p>In addition, designating service staff to monitor and support digital platform use can facilitate the escalation of notifications into clinical actions. The concept of a digital navigator is one such example [<xref ref-type="bibr" rid="ref53">53</xref>,<xref ref-type="bibr" rid="ref54">54</xref>]. A digital navigator in services can alleviate the additional burden placed on clinicians by constantly monitoring the notification system and ensuring timely escalation of notifications. They can also be trained to deliver brief interventions, such as safety planning and safety checks, to help manage service demands [<xref ref-type="bibr" rid="ref50">50</xref>,<xref ref-type="bibr" rid="ref55">55</xref>].</p>
      </sec>
      <sec>
        <title>Limitations</title>
        <p>There are several limitations that should be taken into consideration. First, a higher proportion of participants in this study reported a history of self-harm or suicide attempts compared with previous studies [<xref ref-type="bibr" rid="ref56">56</xref>,<xref ref-type="bibr" rid="ref57">57</xref>]. This characteristic might influence the types of notifications generated and the subsequent responses. However, the primary objective of this study was to demonstrate the feasibility and acceptability of a digital notification system within a mental health service setting. Therefore, the system’s high response rate, despite the frequent generation of alerts, strongly suggests its potential utility in managing cases with high clinical needs. Further research is required to assess its generalizability to populations with different characteristics and in various health care settings. Second, some may suggest that the threshold for a high suicidality notification is too sensitive, capturing individuals who may not have acute needs. However, the primary aim of the notification system is not to identify individuals with immediate suicidal risk. Rather, the notification is designed to inform clinicians about an individual's needs that require response within a reasonable time frame, due to the long-term implications for mental health. This notification system is a tool to facilitate personalized care. A part of enhancing tailored care could involve the use of an advanced machine learning tool that provides a more comprehensive understanding of the volatility of one’s suicidal ideation and behaviors using their longitudinal data [<xref ref-type="bibr" rid="ref34">34</xref>,<xref ref-type="bibr" rid="ref58">58</xref>]. Third, the self-reported measures used can be subject to bias or underreporting. While the self-reported data should be supplemented with clinician reports, the measures used have been well-validated for detecting suicidality. Further, when data is collected longitudinally, it becomes a powerful tool for detecting intraindividual changes [<xref ref-type="bibr" rid="ref59">59</xref>]. Finally, this study does not assess the impact of this notification system on future illness trajectories of youth. Future studies should evaluate the long-term effectiveness of the interventions facilitated by notifications, individual variability in treatment response, and its impact on overall suicidality expressed among youth.</p>
      </sec>
      <sec>
        <title>Conclusions</title>
        <p>This study demonstrates the effectiveness of a digital suicidality notification system in initiating timely clinical actions for young people expressing high suicidality. Further, it highlights that using multidimensional assessments for screening and monitoring of symptoms can be critical for providing personalized treatments. Future research should focus on exploring client and clinician perspectives on using the system to improve its implementation. In addition, examining the longitudinal outcomes of clinical actions initiated by the system would provide insights into their impact on mental health trajectories and suicide rates. Ultimately, this study demonstrates the system’s capacity to enhance service responses to suicidality detected in youth through efficient screening, continuous monitoring, and personalized interventions.</p>
      </sec>
    </sec>
  </body>
  <back>
    <app-group>
      <supplementary-material id="app1">
        <label>Multimedia Appendix 1</label>
        <p>A complete list of measures used in the Innowell Platform.</p>
        <media xlink:href="jmir_v26i1e60879_app1.docx" xlink:title="DOCX File , 25 KB"/>
      </supplementary-material>
      <supplementary-material id="app2">
        <label>Multimedia Appendix 2</label>
        <p>Thresholds for suicidality stratification.</p>
        <media xlink:href="jmir_v26i1e60879_app2.docx" xlink:title="DOCX File , 26 KB"/>
      </supplementary-material>
    </app-group>
    <glossary>
      <title>Abbreviations</title>
      <def-list>
        <def-item>
          <term id="abb1">C-SSRS</term>
          <def>
            <p>Columbia-Suicide Severity Rating Scale</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb2">NEET</term>
          <def>
            <p>Not in employment, education, or training</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb3">SIDAS</term>
          <def>
            <p>Suicidal Ideation Attributes Scale</p>
          </def>
        </def-item>
      </def-list>
    </glossary>
    <ack>
      <p>The funding sources of this study have had no input into the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication. This work was supported by the Medical Research Future Fund Applied Artificial Intelligence in Health Care grant (MRFAI000097). MKC was supported by the Australian Government RTP Scholarship. IBH was supported by an NHMRC Research Fellowship (511921). FI was supported by the Bill and Patricia Richie Foundation and NHMRC EL1 Investigator Grant (GNT2018157). SM was supported by the Cottle Family Fellowship.</p>
      <p>We thank all the young people who participated in this study and all the staff in the Youth Mental Health Team at the University of Sydney’s Brain and Mind Centre, past and present, who contributed to this work.</p>
    </ack>
    <fn-group>
      <fn fn-type="con">
        <p>MKC wrote the manuscript. MKC conducted the formal data analyses. All authors (MKC, IBH, DR, GD, AO, LJB, SM, HML, EMS, and FI) substantively edited and revised the manuscript, approved the final version of the manuscript and agreed both be personally accountable for the author’s own contributions and ensure that questions related to the accuracy or integrity of any part of the work, even ones in which the author was not personally involved, are appropriately investigated, resolved, and the resolution documented in the literature.</p>
      </fn>
      <fn fn-type="conflict">
        <p>IBH is the Codirector, of Health and Policy at the Brain and Mind Centre (BMC) University of Sydney, Australia. The BMC operates early-intervention youth services at Camperdown under contract to Headspace. Professor Hickie has previously led community-based and pharmaceutical industry-supported (Wyeth, Eli Lily, Servier, Pfizer, AstraZeneca, Janssen Cilag) projects focused on the identification and better management of anxiety and depression. He is the Chief Scientific Advisor to, and a 3.2% equity shareholder in, InnoWell Pty Ltd which aims to transform mental health services through the use of innovative technologies. 
        EMS is a Principal Research Fellow at the BMC at the University of Sydney. She is a Discipline Leader of Adult Mental Health at the School of Medicine, University of Notre Dame, and a Consultant Psychiatrist. She was the Medical Director of the Young Adult Mental Health Unit at St Vincent’s Hospital Darlinghurst until January 2021. She has received honoraria for educational seminars related to the clinical management of depressive disorders supported by Servier, Janssen, and Eli-Lilly Pharmaceuticals. She has participated in a national advisory board for the antidepressant compound Pristiq, manufactured by Pfizer. She was the National Coordinator of an antidepressant trial sponsored by Servier.
      No other competing interests were reported.</p>
      </fn>
    </fn-group>
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