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<article xmlns:xlink="http://www.w3.org/1999/xlink" article-type="review-article" dtd-version="2.0">
  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JMIR</journal-id>
      <journal-id journal-id-type="nlm-ta">J Med Internet Res</journal-id>
      <journal-title>Journal of Medical Internet Research</journal-title>
      <issn pub-type="epub">1438-8871</issn>
      <publisher>
        <publisher-name>JMIR Publications</publisher-name>
        <publisher-loc>Toronto, Canada</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">v26i1e51994</article-id>
      <article-id pub-id-type="pmid">39714084</article-id>
      <article-id pub-id-type="doi">10.2196/51994</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Review</subject>
        </subj-group>
        <subj-group subj-group-type="article-type">
          <subject>Review</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Tracking Upper Limb Motion via Wearable Solutions: Systematic Review of Research From 2011 to 2023</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="editor">
          <name>
            <surname>de Azevedo Cardoso</surname>
            <given-names>Taiane</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Okita</surname>
            <given-names>Shusuke</given-names>
          </name>
        </contrib>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Guo</surname>
            <given-names>Liquan</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib id="contrib1" contrib-type="author">
          <name name-style="western">
            <surname>Karoulla</surname>
            <given-names>Eirini</given-names>
          </name>
          <degrees>MEng, MSc</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0009-0008-6624-5744</ext-link>
        </contrib>
        <contrib id="contrib2" contrib-type="author" corresp="yes">
          <name name-style="western">
            <surname>Matsangidou</surname>
            <given-names>Maria</given-names>
          </name>
          <degrees>MA, PhD</degrees>
          <xref rid="aff2" ref-type="aff">2</xref>
          <address>
            <institution>CYENS - Centre of Excellence</institution>
            <addr-line>Lellou Demetriades, Plateia Dimarchou 1</addr-line>
            <addr-line>Nicosia, 1016</addr-line>
            <country>Cyprus</country>
            <phone>357 22747575</phone>
            <email>m.matsangidou@cyens.org.cy</email>
          </address>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0003-3804-5565</ext-link>
        </contrib>
        <contrib id="contrib3" contrib-type="author">
          <name name-style="western">
            <surname>Frangoudes</surname>
            <given-names>Fotos</given-names>
          </name>
          <degrees>BS, MSc</degrees>
          <xref rid="aff2" ref-type="aff">2</xref>
          <xref rid="aff3" ref-type="aff">3</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-2543-8194</ext-link>
        </contrib>
        <contrib id="contrib4" contrib-type="author">
          <name name-style="western">
            <surname>Paspalides</surname>
            <given-names>Panayiotis</given-names>
          </name>
          <degrees>MEng</degrees>
          <xref rid="aff2" ref-type="aff">2</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0009-0009-5661-6895</ext-link>
        </contrib>
        <contrib id="contrib5" contrib-type="author">
          <name name-style="western">
            <surname>Neokleous</surname>
            <given-names>Kleanthis</given-names>
          </name>
          <degrees>MEng, MSc, PhD</degrees>
          <xref rid="aff2" ref-type="aff">2</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0003-4773-9665</ext-link>
        </contrib>
        <contrib id="contrib6" contrib-type="author">
          <name name-style="western">
            <surname>Pattichis</surname>
            <given-names>Constantinos S</given-names>
          </name>
          <degrees>HTI, BSc, MSc, PhD</degrees>
          <xref rid="aff2" ref-type="aff">2</xref>
          <xref rid="aff3" ref-type="aff">3</xref>
          <xref rid="aff4" ref-type="aff">4</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0003-1271-8151</ext-link>
        </contrib>
      </contrib-group>
      <aff id="aff1">
        <label>1</label>
        <institution>CEA-List</institution>
        <institution>Université Paris-Saclay</institution>
        <addr-line>Gif-sur-Yvette</addr-line>
        <country>France</country>
      </aff>
      <aff id="aff2">
        <label>2</label>
        <institution>CYENS - Centre of Excellence</institution>
        <addr-line>Nicosia</addr-line>
        <country>Cyprus</country>
      </aff>
      <aff id="aff3">
        <label>3</label>
        <institution>Department of Computer Science</institution>
        <institution>University of Cyprus</institution>
        <addr-line>Nicosia</addr-line>
        <country>Cyprus</country>
      </aff>
      <aff id="aff4">
        <label>4</label>
        <institution>Biomedical Engineering Research Centre</institution>
        <institution>University of Cyprus</institution>
        <addr-line>Nicosia</addr-line>
        <country>Cyprus</country>
      </aff>
      <author-notes>
        <corresp>Corresponding Author: Maria Matsangidou <email>m.matsangidou@cyens.org.cy</email></corresp>
      </author-notes>
      <pub-date pub-type="collection">
        <year>2024</year>
      </pub-date>
      <pub-date pub-type="epub">
        <day>23</day>
        <month>12</month>
        <year>2024</year>
      </pub-date>
      <volume>26</volume>
      <elocation-id>e51994</elocation-id>
      <history>
        <date date-type="received">
          <day>20</day>
          <month>8</month>
          <year>2023</year>
        </date>
        <date date-type="rev-request">
          <day>17</day>
          <month>3</month>
          <year>2024</year>
        </date>
        <date date-type="rev-recd">
          <day>31</day>
          <month>5</month>
          <year>2024</year>
        </date>
        <date date-type="accepted">
          <day>16</day>
          <month>10</month>
          <year>2024</year>
        </date>
      </history>
      <copyright-statement>©Eirini Karoulla, Maria Matsangidou, Fotos Frangoudes, Panayiotis Paspalides, Kleanthis Neokleous, Constantinos S Pattichis. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 23.12.2024.</copyright-statement>
      <copyright-year>2024</copyright-year>
      <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
        <p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Journal of Medical Internet Research (ISSN 1438-8871), is properly cited. The complete bibliographic information, a link to the original publication on https://www.jmir.org/, as well as this copyright and license information must be included.</p>
      </license>
      <self-uri xlink:href="https://www.jmir.org/2024/1/e51994" xlink:type="simple"/>
      <abstract>
        <sec sec-type="background">
          <title>Background</title>
          <p>The development of wearable solutions for tracking upper limb motion has gained research interest over the past decade. This paper provides a systematic review of related research on the type, feasibility, signal processing techniques, and feedback of wearable systems for tracking upper limb motion, mostly in rehabilitation applications, to understand and monitor human movement.</p>
        </sec>
        <sec sec-type="objective">
          <title>Objective</title>
          <p>The aim of this article is to investigate how wearables are used to capture upper limb functions, especially related to clinical and rehabilitation applications.</p>
        </sec>
        <sec sec-type="methods">
          <title>Methods</title>
          <p>A systematic literature search identified 27 relevant studies published in English from 2011 to 2023, across 4 databases: ACM Digital Library, IEEE Xplore, PubMed, and ScienceDirect. We included papers focusing on motion or posture tracking for the upper limbs, wearable devices, feedback given to end users, and systems having clinical or rehabilitation purposes. We excluded papers focusing on exoskeletons, robotics, prosthetics, orthoses, or activity recognition systems; reviews; and books.</p>
        </sec>
        <sec sec-type="results">
          <title>Results</title>
          <p>The results from this research focus on wearable devices that are designed to monitor upper limb movement. More specifically, studies were divided into 2 distinct categories: clinical motion tracking (15/27, 56%) and rehabilitation (12/27, 44%), involving healthy individuals and patients, with a total of 439 participants. Among the 27 studies, the majority (19/27) used inertial measurement units to track upper limb movement or smart textiles embedded with sensors. These devices were attached to the body with straps (mostly Velcro), providing flexibility and stability. The developed wearable devices positively influenced user motivation through the provided feedback, with visual feedback being the most common owing to the high level of independence provided. Moreover, a variety of signal processing techniques, such as Kalman and Butterworth filters, were applied to ensure data accuracy. However, limitations persist and include sensor positioning, calibration, and battery life, as well as a lack of clinical data on the effectiveness of these systems. The sampling rate of the data collection ranged from 50 Hz to 2000 Hz, which notably affected data quality and battery life. In addition, several findings were inconclusive, and thus, further future research is needed to understand and improve upper limb posture to develop progressive wearable systems.</p>
        </sec>
        <sec sec-type="conclusions">
          <title>Conclusions</title>
          <p>This paper offers a comprehensive overview of wearable monitoring systems, with a focus on upper limb motion tracking and rehabilitation. It emphasizes the various types of available solutions; their efficacy, wearability, and feasibility; and proposed processing techniques. Finally, it presents robust findings regarding feedback accuracy derived from experiments and outlines potential future research directions.</p>
        </sec>
      </abstract>
      <kwd-group>
        <kwd>motion tracking</kwd>
        <kwd>motion sensing</kwd>
        <kwd>posture monitoring</kwd>
        <kwd>wearable devices</kwd>
        <kwd>upper limb rehabilitation</kwd>
        <kwd>interactive feedback</kwd>
        <kwd>real-time feedback</kwd>
        <kwd>wearble technology</kwd>
        <kwd>upper limb motion</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec sec-type="introduction">
      <title>Introduction</title>
      <p>Two out of the three leading conditions driving the need for rehabilitation are musculoskeletal and neurological disorders, with 1.71 billion and 255 million people, respectively, being affected globally. Musculoskeletal disorders have a significant impact on both individuals and society as a whole and incur a substantial economic cost. Thus, their effective and timely treatment through traditional rehabilitation approaches or digital health interventions is very important [<xref ref-type="bibr" rid="ref1">1</xref>]. Carpal tunnel syndrome, rotator cuff tendonitis, and trigger finger are among the most common upper limb musculoskeletal dysfunctions that require methodical rehabilitation treatment [<xref ref-type="bibr" rid="ref2">2</xref>]. People experiencing such disorders are often exposed to physical activities that require repetitive work [<xref ref-type="bibr" rid="ref3">3</xref>].</p>
      <p>Neurological diseases, on the other hand, not only affect the physical movement of patients but also influence their independence, living conditions, and quality of life. Usually, these disorders induce upper limb impairments, which often require conventional interventions to recover, such as physical or occupational therapy [<xref ref-type="bibr" rid="ref4">4</xref>], as their rehabilitation depends on the duration, intensity, onset, and task orientation [<xref ref-type="bibr" rid="ref5">5</xref>]. Stroke is the leading neurological disorder [<xref ref-type="bibr" rid="ref6">6</xref>] and can potentially require long-term rehabilitation, with the affected person sometimes never achieving full recovery [<xref ref-type="bibr" rid="ref7">7</xref>]. The high prevalence of stroke and the unique challenges it introduces have led to many studies about how technology can be used to assist affected populations and how to meet their needs [<xref ref-type="bibr" rid="ref8">8</xref>].</p>
      <p>Over the last 2 decades, technological devices have been included in rehabilitation programs within hospitals and treatment centers, which provide assistance and quantitative analysis during the rehabilitation process. Wearable devices have seen rapid development recently, with new technologies emerging constantly. The sensors used with wearables are getting smaller, more portable, and more energy efficient while, at the same time, having improved accuracy [<xref ref-type="bibr" rid="ref9">9</xref>]. The prevention and rehabilitation of upper limb disorders are major problems that can benefit from the use of advanced wearable recovery systems. However, their integration and adoption in clinical practice are limited, and further actions are required toward this goal [<xref ref-type="bibr" rid="ref6">6</xref>,<xref ref-type="bibr" rid="ref10">10</xref>].</p>
      <p>Therefore, efforts should be focused on developing systems that ensure that researchers can get reliable data for clinical evaluations. In this way, the variations in therapy and functional recovery can be better understood, aiming for the development of intervention strategies and the comprehension of the neuromuscular system [<xref ref-type="bibr" rid="ref6">6</xref>]. Wearable devices are developed to solve these problems by providing affordable home-based solutions. It has been argued that inertial measurement units (IMUs) and surface electromyography (EMG) sensors are among the best options from the wide range of sensors currently available on the market that are used for the collection of data from wearable devices. These sensors offer a good balance between unobtrusiveness, robustness, and data quality [<xref ref-type="bibr" rid="ref7">7</xref>].</p>
      <p>This paper aims to provide a thorough review of how wearable-based monitoring systems are used for upper limb motion tracking and rehabilitation. More specifically, we aim to provide new insights into this area and analyze them in the following aspects: (1) assess the type and effectiveness of each wearable system; (2) assess the wearability and feasibility of the sensing technology; (3) clarify the signal processing techniques and extracted features; (4) classify the type and accuracy of the feedback according to the experiment results; and (5) review the findings, discuss limitations, and propose future directions.</p>
    </sec>
    <sec sec-type="methods">
      <title>Methods</title>
      <sec>
        <title>Review Phases</title>
        <p>The review was conducted based on the Bargas-Avila and Hornbæk approach [<xref ref-type="bibr" rid="ref11">11</xref>] and Cochrane methodology [<xref ref-type="bibr" rid="ref12">12</xref>], and it included 5 phases.</p>
        <sec>
          <title>Phase 1: Potentially Relevant Publications Identified</title>
          <sec>
            <title>Electronic Libraries</title>
            <p>We searched 4 electronic libraries, which cover a balanced range of disciplines, including computer science and engineering, medical research, and multidisciplinary sources. The following libraries were included in the review: (1) ACM Digital Library, (2) IEEE Xplore, (3) PubMed, and (4) ScienceDirect. We restricted the search to a timeframe of 13 years (2011 to 2023).</p>
          </sec>
          <sec>
            <title>Search Terms</title>
            <p>The following queries were used: (1) “upper limb rehabilitation” AND “wearables,” and (2) (“posture monitoring” OR “motion monitoring”) AND “wearables.”</p>
          </sec>
          <sec>
            <title>Search Procedure</title>
            <p>The search terms were applied to the publication’s title, abstract, and keywords.</p>
          </sec>
          <sec>
            <title>Inclusion Criteria</title>
            <p>The inclusion criteria were as follows: (1) the paper concerns motion or posture tracking of the upper limbs, (2) the study focuses on wearable devices, (3) feedback is given to the end users, (4) the system considers clinical or rehabilitation purposes, and (5) the paper has been published in the last 13 years and is written in English.</p>
          </sec>
          <sec>
            <title>Exclusion Criteria</title>
            <p>The exclusion criteria were as follows: (1) robotic and exoskeleton systems, (2) prosthetics and orthoses, (3) activity recognition systems (activity/gesture or motion capture), and (4) reviews and books.</p>
          </sec>
          <sec>
            <title>Search Results</title>
            <p>The total number of search results from phase 1 was 1564 papers. More detailed results are presented in <xref ref-type="table" rid="table1">Table 1</xref>.</p>
            <table-wrap position="float" id="table1">
              <label>Table 1</label>
              <caption>
                <p>Search results per library.</p>
              </caption>
              <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
                <col width="230"/>
                <col width="160"/>
                <col width="160"/>
                <col width="140"/>
                <col width="140"/>
                <col width="170"/>
                <thead>
                  <tr valign="top">
                    <td>Query</td>
                    <td colspan="5">Library (N=1564), n</td>
                  </tr>
                  <tr valign="top">
                    <td>
                      <break/>
                    </td>
                    <td>ACM<sup>a</sup></td>
                    <td>IEEE<sup>b</sup></td>
                    <td>PM<sup>c</sup></td>
                    <td>SD<sup>d</sup></td>
                    <td>Total</td>
                  </tr>
                </thead>
                <tbody>
                  <tr valign="top">
                    <td>Query 1<sup>e</sup></td>
                    <td>338</td>
                    <td>145</td>
                    <td>309</td>
                    <td>78</td>
                    <td>870</td>
                  </tr>
                  <tr valign="top">
                    <td>Query 2<sup>f</sup></td>
                    <td>228</td>
                    <td>99</td>
                    <td>67</td>
                    <td>300</td>
                    <td>694</td>
                  </tr>
                </tbody>
              </table>
              <table-wrap-foot>
                <fn id="table1fn1">
                  <p><sup>a</sup>ACM: ACM Digital Library.</p>
                </fn>
                <fn id="table1fn2">
                  <p><sup>b</sup>IEEE: IEEE Xplore.</p>
                </fn>
                <fn id="table1fn3">
                  <p><sup>c</sup>PM: PubMed.</p>
                </fn>
                <fn id="table1fn4">
                  <p><sup>d</sup>SD: ScienceDirect.</p>
                </fn>
                <fn id="table1fn5">
                  <p><sup>e</sup>Query 1: “upper limb rehabilitation” AND “wearables.”</p>
                </fn>
                <fn id="table1fn6">
                  <p><sup>f</sup>Query 2: (“posture monitoring” OR “motion monitoring”) AND “wearables.”</p>
                </fn>
              </table-wrap-foot>
            </table-wrap>
          </sec>
        </sec>
        <sec>
          <title>Phase 2: Publications Retrieved for Detailed Evaluation</title>
          <sec>
            <title>First Exclusion</title>
            <p>All 1564 search results from phase 1 were imported into the software “Paperpile.” Duplicate entities were excluded manually. Overall, 96 duplicate publications were removed, and 1468 papers remained.</p>
          </sec>
          <sec>
            <title>Second Exclusion</title>
            <p>Publications with incomplete or restricted entries, those with no available full text, and those considered irrelevant based on the abstract were excluded manually. As a result, 1110 papers were removed.</p>
          </sec>
          <sec>
            <title>Third Exclusion</title>
            <p>We narrowed the entries to original full papers written in English. Part of this third exclusion was to remove entities that were not original full papers, such as workshops, posters, speeches, reviews, magazine articles, and generally grey literature without formal peer review. As a result, 51 papers were excluded. The remaining 307 papers included 255 journal articles, 45 conference papers, and 7 book chapters. </p>
          </sec>
        </sec>
        <sec>
          <title>Phase 3: Publications to be Included in the Analysis</title>
          <sec>
            <title>Final Exclusion</title>
            <p>The focus of this review is on tracking upper limb motion via wearable solutions. Consequently, this final exclusion phase excluded studies that were not relevant based on a full-text review. Based on the exclusion criteria, we removed 280 irrelevant publications (eg, exoskeleton, robotics, and orthosis), and finally, 27 papers were selected for analysis.</p>
          </sec>
          <sec>
            <title>Phase 4: Data Gathering</title>
            <p>The screening process and data extraction were performed independently by 3 researchers (EK, MM, and PP). Discrepancies between reviewers were resolved through regular meetings and detailed discussions, addressing all the disagreements to minimize bias. In this phase, relevant information was extracted from the selected papers to conduct the analysis. From each study, the following information was extracted: target population, sample size of participants, sensor placement, type of the wearable system, type and feasibility of wearability, data sampling rate, energy consumption/battery characteristics, type and accuracy of feedback according to statistical analysis results, methodology, measurement techniques, instruments, key findings, limitations, and future directions.</p>
          </sec>
          <sec>
            <title>Phase 5: Data Analysis </title>
            <p>The data collected in phase 4 were analyzed using descriptive statistics. We then reviewed the literature to support and enhance the additional knowledge that this paper provides. Thematic analysis was used as an extra methodology to categorize our findings based on themes: (1) type and effectiveness of wearable systems, (2) wearability of sensing technology, (3) data processing and measurement techniques, and (4) type and accuracy of feedback.</p>
          </sec>
        </sec>
      </sec>
    </sec>
    <sec sec-type="results">
      <title>Results</title>
      <sec>
        <title>Study Characteristics</title>
        <p>The review identified 27 studies (<xref rid="figure1" ref-type="fig">Figure 1</xref>). All the reviewed studies tracked upper limb motion using wearable devices and were divided into 2 main categories according to the purpose of the study: (1) clinical motion tracking and (2) rehabilitation. Some studies examined both applications. More specifically, the majority of papers that were selected (15/27, 56%) [<xref ref-type="bibr" rid="ref13">13</xref>-<xref ref-type="bibr" rid="ref27">27</xref>] focused on wearable devices that monitor human movement, and data were collected to be employed for general use in a clinical setting. The remaining papers (12/27, 44%) [<xref ref-type="bibr" rid="ref28">28</xref>-<xref ref-type="bibr" rid="ref39">39</xref>] emphasized systems for upper limb rehabilitation. The PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) checklist is provided in <xref ref-type="supplementary-material" rid="app1">Multimedia Appendix 1</xref>.</p>
        <p>The key features of the studies are summarized and compared in <xref ref-type="table" rid="table2">Table 2</xref>, according to the purpose of the study, the type and number of sensors used, the placement location of the sensors, the placement method for the sensors, and the measurement method, with division into the 2 aforementioned categories.</p>
        <fig id="figure1" position="float">
          <label>Figure 1</label>
          <caption>
            <p>Identification and selection flow diagram.</p>
          </caption>
          <graphic xlink:href="jmir_v26i1e51994_fig1.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
        </fig>
        <table-wrap position="float" id="table2">
          <label>Table 2</label>
          <caption>
            <p>Key features of the studies.</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="30"/>
            <col width="120"/>
            <col width="0"/>
            <col width="240"/>
            <col width="0"/>
            <col width="160"/>
            <col width="0"/>
            <col width="120"/>
            <col width="0"/>
            <col width="130"/>
            <col width="0"/>
            <col width="200"/>
            <thead>
              <tr valign="top">
                <td colspan="3">Content and study</td>
                <td colspan="2">Purpose</td>
                <td colspan="2">Technology (number of sensors)</td>
                <td colspan="2">Placement location</td>
                <td colspan="2">Placement method</td>
                <td>Measurement/methodology</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td colspan="12">
                  <bold>Motion tracking</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Yu et al [<xref ref-type="bibr" rid="ref27">27</xref>]</td>
                <td colspan="2">Monitor upper limb motion function of stroke patients</td>
                <td colspan="2">Accelerometer (n=2)</td>
                <td colspan="2">Forearm, upper arm</td>
                <td colspan="2">Straps</td>
                <td colspan="2">ROM<sup>a</sup>: Bobath’s handshake and shoulder touch</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Wang et al [<xref ref-type="bibr" rid="ref24">24</xref>]</td>
                <td colspan="2">Monitor compensatory movements and evaluate their applicability in a clinical setting</td>
                <td colspan="2">9-DOF<sup>b</sup> IMU<sup>c</sup> (n=2)</td>
                <td colspan="2">Shoulder, torso</td>
                <td colspan="2">Zipped vest, Velcro straps</td>
                <td colspan="2">Compensatory movement of the shoulder girdle</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Li et al [<xref ref-type="bibr" rid="ref18">18</xref>]</td>
                <td colspan="2">Evaluate upper limb motor function in hemiplegic patients</td>
                <td colspan="2">6-DOF IMU (n=2), EMG<sup>d</sup> (n=10)</td>
                <td colspan="2">Wrist, forearm, upper arm</td>
                <td colspan="2">Wristband, armband</td>
                <td colspan="2">Movements of major upper limb joints: shoulder, elbow, wrist, and finger joints</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Repnik et al [<xref ref-type="bibr" rid="ref20">20</xref>]</td>
                <td colspan="2">Quantify upper limb movement for muscle activity analysis in stroke patients</td>
                <td colspan="2">9-DOF IMU (n=7), EMG (n=2)</td>
                <td colspan="2">Hand, wrist, forearm, upper arm, sternum</td>
                <td colspan="2">Wristband, armband, straps</td>
                <td colspan="2">Movement quantified: hand smoothness, trajectory, trunk stability, and muscle activity</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Tolvanen et al [<xref ref-type="bibr" rid="ref23">23</xref>]</td>
                <td colspan="2">General motion tracking</td>
                <td colspan="2">Piezoresistive strain sensor (n=1)</td>
                <td colspan="2">Hand, wrist, forearm, upper arm (biceps, triceps)</td>
                <td colspan="2">Reusable adhesive layer</td>
                <td colspan="2">Opening-closing cycles (hand), muscle tension of the flexor sternum, biceps, upper arm, bicep curl, peck fly, and triceps</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Bai et al [<xref ref-type="bibr" rid="ref13">13</xref>]</td>
                <td colspan="2">Monitor different body movements, muscle contraction, and relaxation</td>
                <td colspan="2">GYS<sup>e</sup> sensor</td>
                <td colspan="2">Upper arm, fingers</td>
                <td colspan="2">Direct winding</td>
                <td colspan="2">ROM: instant tensing, bending, static motions of fingers, varied contractions of the bicep</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Gu et al [<xref ref-type="bibr" rid="ref15">15</xref>]</td>
                <td colspan="2">Identify hand motions, joint bending, hand posture, gesture, and sign language</td>
                <td colspan="2">Hydrogel-elastomer hybrid ionic sensor (n=10)</td>
                <td colspan="2">Hand, fingers</td>
                <td colspan="2">Water-borne adhesive</td>
                <td colspan="2">ROM: finger bending/extending and hand gestures</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Lee et al [<xref ref-type="bibr" rid="ref17">17</xref>]</td>
                <td colspan="2">Analyze data from neurologically intact individuals and the free-living environment, and develop a system to monitor stroke survivors</td>
                <td colspan="2">Accelerometer (n=4)</td>
                <td colspan="2">Wrists, fingers</td>
                <td colspan="2">Rings, wristbands</td>
                <td colspan="2">General quantification of the amount of use of upper limb function</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Zhang P et al [<xref ref-type="bibr" rid="ref26">26</xref>]</td>
                <td colspan="2">Monitor human movement with the use of a flexible resistance strain sensor with a porous structure</td>
                <td colspan="2">Strain sensor (n=1)</td>
                <td colspan="2">Upper arm, forearm, wrist, fingers</td>
                <td colspan="2">Velcro straps</td>
                <td colspan="2">ROM: finger wrist and elbow bending; responses to breathing</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Lee et al [<xref ref-type="bibr" rid="ref16">16</xref>]</td>
                <td colspan="2">Facilitate the clinically fitted measurement of fine-motor finger and wrist joint movements. Characterize age-related changes in hand functions</td>
                <td colspan="2">9-DOF IMU (n=7)</td>
                <td colspan="2">Wrist, hand, fingers</td>
                <td colspan="2">Clip-on straps</td>
                <td colspan="2">ROM: finger movement (index finger, thumb flexion/extension) and wrist movement (ulnar/radial flexion)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Zhang J et al [<xref ref-type="bibr" rid="ref25">25</xref>]</td>
                <td colspan="2">Implement 3D motion velocity measurement, and propose a functional link artificial neural network model (FLANN)</td>
                <td colspan="2">Microthermal flow sensor (n=2)</td>
                <td colspan="2">Wrist</td>
                <td colspan="2">Straps</td>
                <td colspan="2">Trunk velocity, relative limb velocity, and absolute limb velocity</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Schwarz et al [<xref ref-type="bibr" rid="ref21">21</xref>]</td>
                <td colspan="2">Evaluate spatiotemporal kinematic metrics for the assessment of upper limb movements after stroke</td>
                <td colspan="2">6-DOF IMU (n=8)</td>
                <td colspan="2">Sternum, shoulder, upper arm, forearm, hand, fingers, thumb</td>
                <td colspan="2">Medical tape/3D-printed flexible straps</td>
                <td colspan="2">ROM: shoulder, elbow, thumb, index flexion/extension, and wrist supination/pronation</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Formstone et al [<xref ref-type="bibr" rid="ref14">14</xref>]</td>
                <td colspan="2">Develop a comprehensive system designed for the clinical environment, and quantify hand/wrist movement</td>
                <td colspan="2">9-DOF IMU (n=3), MMG<sup>f</sup> (n=2)</td>
                <td colspan="2">Sternum, upper arm, wrist, forearm</td>
                <td colspan="2">3D-printed housing cases attached with 3D-printed flexible resin straps</td>
                <td colspan="2">Shoulder twist angle (range), abduction, flexion, elbow twist angle, wrist flexion, and circumduction muscle activity</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Little et al [<xref ref-type="bibr" rid="ref19">19</xref>]</td>
                <td colspan="2">Analyze kinematic and physiological features for predicting elbow motion intention</td>
                <td colspan="2">9-DOF IMU (n=3), EMG (n=4), stretch sensor (n=1)</td>
                <td colspan="2">Forearm, upper arm, torso</td>
                <td colspan="2">Straps, direct winding</td>
                <td colspan="2">Muscle activity, elbow flexion angle, and custom-made changes in muscle volume</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Schwerz de Lucena et al [<xref ref-type="bibr" rid="ref22">22</xref>]</td>
                <td colspan="2">Real-time quantification of the effect of wearable feedback on hand counts for increasing hand activity</td>
                <td colspan="2">6-DOF IMU (n=1), magnetometer (n=4)</td>
                <td colspan="2">Wrist, fingers</td>
                <td colspan="2">Wristband, ring</td>
                <td colspan="2">“Hand counts”: finger flexion/extension, wrist flexion/extension, and wrist radial/ulnar deviation movement</td>
              </tr>
              <tr valign="top">
                <td colspan="12">
                  <bold>Rehabilitation</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Ding et al [<xref ref-type="bibr" rid="ref39">39</xref>]</td>
                <td colspan="2">Measure orientation and correct arm posture using vibrotactile actuators for stroke rehabilitation patients and therapists</td>
                <td colspan="2">9-DOF IMU (n=2)</td>
                <td colspan="2">Forearm, upper arm</td>
                <td colspan="2">Velcro straps</td>
                <td colspan="2">Body segment posture; forearm and upper arm orientation; trajectory of upper arm’s yaw, pitch, and roll; elbow angle; and forearm roll</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Kim et al [<xref ref-type="bibr" rid="ref31">31</xref>]</td>
                <td colspan="2">Wearable upper limb motion tracking method for stroke rehabilitation therapy at home</td>
                <td colspan="2">6-DOF IMU (n=2)</td>
                <td colspan="2">Wrist, upper arm</td>
                <td colspan="2">Velcro straps</td>
                <td colspan="2">ROM: position and orientation of the wrist and elbow joints. Accuracy of motion estimation and motion matching</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Mohammadzadeh et al [<xref ref-type="bibr" rid="ref34">34</xref>]</td>
                <td colspan="2">Develop and evaluate the feasibility of a wearable sensor-based motion-tracking system</td>
                <td colspan="2">6-DOF IMU (n=3)</td>
                <td colspan="2">Forearm, upper arm, sternum</td>
                <td colspan="2">Velcro straps</td>
                <td colspan="2">ROM: elbow joint angle</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Ploderer et al [<xref ref-type="bibr" rid="ref35">35</xref>]</td>
                <td colspan="2">Patient monitoring system to support occupational therapists in upper limb rehabilitation work with stroke patients</td>
                <td colspan="2">9-DOF IMU (n=3)</td>
                <td colspan="2">Shoulder, upper arm, wrist</td>
                <td colspan="2">Velcro straps, medical tape</td>
                <td colspan="2">ROM of each degree of freedom</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Wang et al [<xref ref-type="bibr" rid="ref28">28</xref>]</td>
                <td colspan="2">Evaluate garments equipped with sensors that support posture monitoring; used in upper extremity rehabilitation training of stroke patients</td>
                <td colspan="2">9-DOF IMU (n=3)</td>
                <td colspan="2">Scapula (shoulder blade), torso</td>
                <td colspan="2">Vest with Velcro straps</td>
                <td colspan="2">Analytical shoulder flexion, and analytical and functional elevation in the scapular plane</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Salchow-Hömmen et al [<xref ref-type="bibr" rid="ref37">37</xref>]</td>
                <td colspan="2">Part of a feedback-controlled hand neuroprosthesis for the rehabilitation of patients who experience motor impairment of the hand</td>
                <td colspan="2">9-DOF IMU (n=16)</td>
                <td colspan="2">Hand, fingers, forearm</td>
                <td colspan="2">Skin-friendly tape</td>
                <td colspan="2">ROM: combined abduction and flexion motion</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Semjonova et al [<xref ref-type="bibr" rid="ref38">38</xref>]</td>
                <td colspan="2">Evaluate the impact of the Double Aid (DAid) smart shirt; training process of patients with subacromial pain syndrome</td>
                <td colspan="2">Strain sensors (n=2)</td>
                <td colspan="2">Scapula</td>
                <td colspan="2">Commercial elastane-based fitness shirt</td>
                <td colspan="2">Perform exercise without moving the shoulders; detect movement or no movement of the shoulders</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Friedman et al [<xref ref-type="bibr" rid="ref29">29</xref>]</td>
                <td colspan="2">Nonobtrusive option for monitoring wrist and hand movement; needed for stroke rehabilitation and other applications</td>
                <td colspan="2">Triaxial magnetometer (n=2), accelerometer (n=1)</td>
                <td colspan="2">Wrist, fingers</td>
                <td colspan="2">Watch-like enclosure, small neodymium ring worn on the index finger</td>
                <td colspan="2">Accuracy of monitoring finger motion, wrist flexion/extension, and wrist ulnar/radial deviation. Accuracy in estimating different levels of movement activity</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Kortier et al [<xref ref-type="bibr" rid="ref32">32</xref>]</td>
                <td colspan="2">Ambulatory system using inertial sensors for hand kinematics, and evaluation of hand functioning</td>
                <td colspan="2">6-DOF IMU (n=15), 9-DOF IMU (n=6)</td>
                <td colspan="2">Hand, fingers, thumb</td>
                <td colspan="2">Double-sided adhesive tape/mounted on polyamide/elastane-fabricated glove</td>
                <td colspan="2">Static accuracy (ROM: flexion/extension, dynamic range, and repeatability)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Kim et al [<xref ref-type="bibr" rid="ref30">30</xref>]</td>
                <td colspan="2">Identify optimal sensor locations</td>
                <td colspan="2">Bending sensor (n=2)</td>
                <td colspan="2">Thumb, hand</td>
                <td colspan="2">Flexible fabric straps partially made of Lycra sewed on a glove structure</td>
                <td colspan="2">ROM; circumduction motion</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Liu et al [<xref ref-type="bibr" rid="ref33">33</xref>]</td>
                <td colspan="2">Primary use of conductive stretchable fabrics to sense skin deformation during joint motion and infer the joint rotational angle</td>
                <td colspan="2">Strain sensor (n=2)</td>
                <td colspan="2">Forearm</td>
                <td colspan="2">Fabric</td>
                <td colspan="2">ROM: elbow flexion by various degrees; repeat motion at 3 levels of speed. Repeat each motion and perform free-form motions</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Pregnolato et al [<xref ref-type="bibr" rid="ref36">36</xref>]</td>
                <td colspan="2">Define the clinical features of stroke patients while performing hand movements for rehabilitation training</td>
                <td colspan="2">9-DOF IMU (n=1), EMG (n=1)</td>
                <td colspan="2">Forearm</td>
                <td colspan="2">Armband</td>
                <td colspan="2"> Detect the total muscle activity of the forearm circumference</td>
              </tr>
            </tbody>
          </table>
          <table-wrap-foot>
            <fn id="table2fn1">
              <p><sup>a</sup>ROM: range of motion.</p>
            </fn>
            <fn id="table2fn2">
              <p><sup>b</sup>DOF: degrees of freedom.</p>
            </fn>
            <fn id="table2fn3">
              <p><sup>c</sup>IMU: inertial measurement unit.</p>
            </fn>
            <fn id="table2fn4">
              <p><sup>d</sup>EMG: electromyography.</p>
            </fn>
            <fn id="table2fn5">
              <p><sup>e</sup>GYS: graphene thin-film yarn sensor.</p>
            </fn>
            <fn id="table2fn6">
              <p><sup>f</sup>MMG: mechanomyography.</p>
            </fn>
          </table-wrap-foot>
        </table-wrap>
      </sec>
      <sec>
        <title>Study Type and Effectiveness</title>
        <p>As mentioned above, wearable devices are used to capture upper limb function for general health purposes to obtain information and data about physiological parameters to assist rehabilitation patients and therapists. The experiments in most of the studies (22/27) [<xref ref-type="bibr" rid="ref13">13</xref>-<xref ref-type="bibr" rid="ref19">19</xref>,<xref ref-type="bibr" rid="ref21">21</xref>,<xref ref-type="bibr" rid="ref22">22</xref>,<xref ref-type="bibr" rid="ref24">24</xref>-<xref ref-type="bibr" rid="ref26">26</xref>,<xref ref-type="bibr" rid="ref28">28</xref>,<xref ref-type="bibr" rid="ref29">29</xref>,<xref ref-type="bibr" rid="ref31">31</xref>-<xref ref-type="bibr" rid="ref37">37</xref>,<xref ref-type="bibr" rid="ref39">39</xref>] were noncontrolled experiments, where participants were either healthy able-bodied individuals or patients who experienced upper limb disorder, and they were recruited for participation in the experimental evaluation. In some studies (4/27) [<xref ref-type="bibr" rid="ref20">20</xref>,<xref ref-type="bibr" rid="ref27">27</xref>,<xref ref-type="bibr" rid="ref30">30</xref>,<xref ref-type="bibr" rid="ref38">38</xref>], the experiments were controlled, where both patients and healthy participants were included and the results were compared statistically. The number of participants was not specified in 1 study [<xref ref-type="bibr" rid="ref23">23</xref>].</p>
        <p>The findings revealed that most of the studies (22/27) [<xref ref-type="bibr" rid="ref13">13</xref>-<xref ref-type="bibr" rid="ref19">19</xref>,<xref ref-type="bibr" rid="ref23">23</xref>-<xref ref-type="bibr" rid="ref29">29</xref>,<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref32">32</xref>,<xref ref-type="bibr" rid="ref34">34</xref>-<xref ref-type="bibr" rid="ref39">39</xref>] had a positive outcome. In 2 cases [<xref ref-type="bibr" rid="ref22">22</xref>,<xref ref-type="bibr" rid="ref30">30</xref>], further studies need to be conducted. In the first study, the maximum estimated error exceeded the required accuracy for a typical clinical assessment (over 5 degrees). In the second study, the hand feedback for stroke patients was briefly modifiable, indicating no therapeutic benefit over a short period. Thus, these studies are considered neutral. The outcomes of the remaining 3 studies [<xref ref-type="bibr" rid="ref20">20</xref>,<xref ref-type="bibr" rid="ref21">21</xref>,<xref ref-type="bibr" rid="ref33">33</xref>] were negative as they do not offer any major findings [<xref ref-type="bibr" rid="ref20">20</xref>] on motion tracking and the application is difficult to implement [<xref ref-type="bibr" rid="ref21">21</xref>,<xref ref-type="bibr" rid="ref33">33</xref>] due to limitations such as the system’s measurement accuracy and large errors.</p>
        <p>From the above information, it can be concluded that motion-tracking wearable devices have an overall positive impact on the interpretation of the data, and they provide useful assessments that can be used in future systems for clinical and rehabilitation purposes. The aforementioned data are presented in <xref ref-type="table" rid="table3">Table 3</xref>, categorized according to the purpose of the study.</p>
        <table-wrap position="float" id="table3">
          <label>Table 3</label>
          <caption>
            <p>Study type and target population.</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="30"/>
            <col width="300"/>
            <col width="0"/>
            <col width="250"/>
            <col width="0"/>
            <col width="420"/>
            <col width="0"/>
            <thead>
              <tr valign="top">
                <td colspan="3">Content and study</td>
                <td colspan="2">Study type</td>
                <td colspan="2">Target population</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td colspan="7">
                  <bold>Motion tracking</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Yu et al [<xref ref-type="bibr" rid="ref27">27</xref>]</td>
                <td colspan="2">Controlled</td>
                <td colspan="2">23 stroke patients, 4 physicians</td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Wang et al [<xref ref-type="bibr" rid="ref24">24</xref>]</td>
                <td colspan="2">Noncontrolled</td>
                <td colspan="2">8 musculoskeletal shoulder pain patients</td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Li et al [<xref ref-type="bibr" rid="ref18">18</xref>]</td>
                <td colspan="2">Noncontrolled</td>
                <td colspan="2">16 healthy adults</td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Repnik et al [<xref ref-type="bibr" rid="ref20">20</xref>]</td>
                <td colspan="2">Controlled</td>
                <td colspan="2">28 stroke patients, 14 healthy adults</td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Tolvanen et al [<xref ref-type="bibr" rid="ref23">23</xref>]</td>
                <td colspan="2">Not specified</td>
                <td colspan="2">Not specified</td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Bai et al [<xref ref-type="bibr" rid="ref13">13</xref>]</td>
                <td colspan="2">Noncontrolled</td>
                <td colspan="2">1 healthy adult</td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Gu et al [<xref ref-type="bibr" rid="ref15">15</xref>]</td>
                <td colspan="2">Noncontrolled</td>
                <td colspan="2">1 healthy adult</td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Lee et al [<xref ref-type="bibr" rid="ref17">17</xref>]</td>
                <td colspan="2">Noncontrolled</td>
                <td colspan="2">35 healthy adults</td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Zhang P et al [<xref ref-type="bibr" rid="ref26">26</xref>]</td>
                <td colspan="2">Noncontrolled</td>
                <td colspan="2">1 healthy adult</td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Lee et al [<xref ref-type="bibr" rid="ref16">16</xref>]</td>
                <td colspan="2">Noncontrolled</td>
                <td colspan="2">34 healthy adults</td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Zhang J et al [<xref ref-type="bibr" rid="ref25">25</xref>]</td>
                <td colspan="2">Noncontrolled</td>
                <td colspan="2">1 healthy adult</td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Schwarz et al [<xref ref-type="bibr" rid="ref21">21</xref>]</td>
                <td colspan="2">Noncontrolled</td>
                <td colspan="2">9 stroke patients</td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Formstone et al [<xref ref-type="bibr" rid="ref14">14</xref>]</td>
                <td colspan="2">Noncontrolled</td>
                <td colspan="2">3 healthy adults</td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Little et al [<xref ref-type="bibr" rid="ref19">19</xref>]</td>
                <td colspan="2">Noncontrolled</td>
                <td colspan="2">3 healthy adults</td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Schwerz de Lucena et al [<xref ref-type="bibr" rid="ref22">22</xref>]</td>
                <td colspan="2">Noncontrolled</td>
                <td colspan="2">20 chronic stroke patients</td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td colspan="7">
                  <bold>Rehabilitation</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Ding et al [<xref ref-type="bibr" rid="ref39">39</xref>]</td>
                <td colspan="2">Noncontrolled</td>
                <td colspan="2">5 healthy adults</td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Kim et al [<xref ref-type="bibr" rid="ref31">31</xref>]</td>
                <td colspan="2">Noncontrolled</td>
                <td colspan="2">4 healthy adults</td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Mohammadzadeh et al [<xref ref-type="bibr" rid="ref34">34</xref>]</td>
                <td colspan="2">Noncontrolled</td>
                <td colspan="2">8 healthy adults</td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Ploderer et al [<xref ref-type="bibr" rid="ref35">35</xref>]</td>
                <td colspan="2">Noncontrolled</td>
                <td colspan="2">1st study: 8 occupational therapists; 2nd study: 1 healthy participant; 3rd study: 2 occupational therapists</td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Salchow-Hömmen et al [<xref ref-type="bibr" rid="ref37">37</xref>]</td>
                <td colspan="2">Noncontrolled</td>
                <td colspan="2">4 healthy adults</td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Semjonova et al [<xref ref-type="bibr" rid="ref38">38</xref>]</td>
                <td colspan="2">Controlled</td>
                <td colspan="2">17 primary subacromial pain syndrome patients and 17 healthy adults</td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Wang et al [<xref ref-type="bibr" rid="ref28">28</xref>]</td>
                <td colspan="2">Noncontrolled</td>
                <td colspan="2">17 stroke patients</td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Friedman et al [<xref ref-type="bibr" rid="ref29">29</xref>]</td>
                <td colspan="2">Noncontrolled</td>
                <td colspan="2">7 healthy adults</td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Kortier et al [<xref ref-type="bibr" rid="ref32">32</xref>]</td>
                <td colspan="2">Noncontrolled</td>
                <td colspan="2">1st study: 1 participant; 2nd study: 1 participant; 3rd study: 5 participants</td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Kim et al [<xref ref-type="bibr" rid="ref30">30</xref>]</td>
                <td colspan="2">Noncontrolled</td>
                <td colspan="2">10 participants for the optimal sensor location and 4 participants for experimental evaluation</td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Liu et al [<xref ref-type="bibr" rid="ref33">33</xref>]</td>
                <td colspan="2">Noncontrolled</td>
                <td colspan="2">10 healthy adults</td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Pregnolato et al [<xref ref-type="bibr" rid="ref36">36</xref>]</td>
                <td colspan="2">Noncontrolled</td>
                <td colspan="2">117 stroke adults</td>
                <td>
                  <break/>
                </td>
              </tr>
            </tbody>
          </table>
        </table-wrap>
      </sec>
      <sec>
        <title>Wearability and Feasibility of Sensing Technologies</title>
        <sec>
          <title>Categorization of Wearable Sensors</title>
          <p>Capturing the motion of the upper limbs through sensor technologies has been essential for the development of interactive wearable devices for rehabilitation and clinical setting purposes. From the reviewed papers, 4 main categories of sensing technologies were identified: (1) inertial-based sensors (accelerometer, magnetometer, and IMU); (2) bending, force, and strain sensors (bending/stretch sensor and strain sensor [piezoresistive strain sensor and hydrogel-elastomer ionic sensor]); (3) myography sensors (EMG and mechanomyography [MMG]); and (4) other sensors (graphene thin-film yarn sensor [GYS] and microthermal flow sensor).</p>
          <p><xref rid="figure2" ref-type="fig">Figure 2</xref> provides an overview of the number of sensing technologies that were used in the studies, according to the type of sensor.</p>
          <fig id="figure2" position="float">
            <label>Figure 2</label>
            <caption>
              <p>Categorization of sensing technology. DOF: degrees of freedom; EMG: electromyography; GYS: graphene thin-film yarn sensor; IMU: inertial measurement unit; MMG: mechanomyography.</p>
            </caption>
            <graphic xlink:href="jmir_v26i1e51994_fig2.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
          </fig>
          <p>As <xref rid="figure2" ref-type="fig">Figure 2</xref> shows, inertial sensors are the most common type of sensor used for data acquisition (19/27) [<xref ref-type="bibr" rid="ref14">14</xref>,<xref ref-type="bibr" rid="ref16">16</xref>-<xref ref-type="bibr" rid="ref22">22</xref>,<xref ref-type="bibr" rid="ref24">24</xref>,<xref ref-type="bibr" rid="ref27">27</xref>-<xref ref-type="bibr" rid="ref29">29</xref>,<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref32">32</xref>,<xref ref-type="bibr" rid="ref34">34</xref>-<xref ref-type="bibr" rid="ref37">37</xref>,<xref ref-type="bibr" rid="ref39">39</xref>]. An inertial sensor is an electronic device that measures the force and the angular rate of a body, which can be achieved by a combination of 3 embedded sensors: accelerometer, gyroscope, and magnetometer. It can also be used to calculate the orientation of the body. The accelerometer measures the proper acceleration, the gyroscope is used for measuring orientation and angular velocity, and finally, the magnetometer measures the strength and sometimes the direction of the magnetic field. Of the 19 studies, 14 [<xref ref-type="bibr" rid="ref16">16</xref>,<xref ref-type="bibr" rid="ref17">17</xref>,<xref ref-type="bibr" rid="ref21">21</xref>,<xref ref-type="bibr" rid="ref24">24</xref>,<xref ref-type="bibr" rid="ref27">27</xref>-<xref ref-type="bibr" rid="ref29">29</xref>,<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref32">32</xref>,<xref ref-type="bibr" rid="ref34">34</xref>,<xref ref-type="bibr" rid="ref35">35</xref>,<xref ref-type="bibr" rid="ref37">37</xref>-<xref ref-type="bibr" rid="ref39">39</xref>] used a combination of the 3 sensors to measure upper limb posture. More specifically, in 6 studies [<xref ref-type="bibr" rid="ref16">16</xref>,<xref ref-type="bibr" rid="ref24">24</xref>,<xref ref-type="bibr" rid="ref28">28</xref>,<xref ref-type="bibr" rid="ref35">35</xref>,<xref ref-type="bibr" rid="ref37">37</xref>,<xref ref-type="bibr" rid="ref39">39</xref>], 9 degrees of freedom (DOF) inertial sensors were used, including a 3-axis accelerometer, a 3-axis gyroscope, and a 3-axis magnetometer. In 3 studies [<xref ref-type="bibr" rid="ref21">21</xref>,<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref34">34</xref>], the magnetometer was excluded from the data fusion, and 6-DOF inertial sensors were proposed. Two of the studies [<xref ref-type="bibr" rid="ref17">17</xref>,<xref ref-type="bibr" rid="ref27">27</xref>] used only accelerometers as their sensing technology, while in 1 study [<xref ref-type="bibr" rid="ref29">29</xref>], only a magnetometer was included. Moreover, a combination of 6-DOF and 9-DOF IMUs was used [<xref ref-type="bibr" rid="ref32">32</xref>] to measure finger movement for the assessment of hand kinematics while using inertial sensors. Another way to capture wrist and finger motion was introduced by Schwerz de Lucena et al [<xref ref-type="bibr" rid="ref22">22</xref>], where magnetometers were placed on the wrist to capture the magnetic field changes of the index finger, and the orientation of the wrist was quantified by a 6-DOF IMU. Furthermore, Pregnolato et al [<xref ref-type="bibr" rid="ref36">36</xref>] used a combination of a 9-DOF IMU with EMG. Only the gyroscope of the inertial sensor was used to place the device on the patient’s forearm, and EMG was used to detect the overall muscle activity in the circumference. The remaining 4 studies [<xref ref-type="bibr" rid="ref14">14</xref>,<xref ref-type="bibr" rid="ref18">18</xref>-<xref ref-type="bibr" rid="ref20">20</xref>], proposed a fusion of inertial sensors with EMG or MMG [<xref ref-type="bibr" rid="ref14">14</xref>,<xref ref-type="bibr" rid="ref18">18</xref>,<xref ref-type="bibr" rid="ref20">20</xref>] and a stretch sensor [<xref ref-type="bibr" rid="ref19">19</xref>] to measure myographic data and changes in muscle volume, respectively.</p>
          <p>In addition, the use of bending sensors and strain sensors was proposed in 2 papers [<xref ref-type="bibr" rid="ref30">30</xref>,<xref ref-type="bibr" rid="ref38">38</xref>]. This type of sensor was introduced owing to the limited available information on the actual impact of smart garments on clinical outcomes in physiotherapy [<xref ref-type="bibr" rid="ref38">38</xref>] and the inaccurate measurement of thumb carpometacarpal joint movements [<xref ref-type="bibr" rid="ref30">30</xref>]. Semjonova et al [<xref ref-type="bibr" rid="ref38">38</xref>] proposed a purely textile-based smart shirt for the training process of patients with subacromial pain syndrome, while another study [<xref ref-type="bibr" rid="ref30">30</xref>] presented a novel approach to identify optimal sensor locations to properly measure carpometacarpal joint configurations. Low-cost everyday fabrics were also introduced [<xref ref-type="bibr" rid="ref33">33</xref>], which consist of stretchable conductive fabrics as strain sensors to sense skin deformations during elbow joint motion and infer the joint rotation angle. Furthermore, 1 study [<xref ref-type="bibr" rid="ref23">23</xref>] proposed strain sensors along with a highly functional piezoresistive strain sensor, which was designed and fabricated exclusively because it provides excellent durability in human motion monitoring. Strain [<xref ref-type="bibr" rid="ref26">26</xref>] and hydrogel-elastomer ionic [<xref ref-type="bibr" rid="ref15">15</xref>] sensors are also used as they provide flexibility when they are worn, allowing the precise monitoring of upper limb movement and respiratory changes.</p>
          <p>An alternative approach was also provided [<xref ref-type="bibr" rid="ref13">13</xref>,<xref ref-type="bibr" rid="ref25">25</xref>] as microthermal flow sensors and GYSs were introduced. The former method calculates velocity without integral calculation, and thus, accumulated errors are excluded. In the latter, the degree of resistance recovery and the gauge sensitivity can be well controlled and modulated, providing high evaluability for developing next-generation wearable electronics.</p>
          <p>The placement of each sensor can vary greatly, including the core of the body, across the arm, and on the fingers, according to the intended application. <xref ref-type="table" rid="table4">Table 4</xref> provides information about the number and placement of sensors, and <xref rid="figure3" ref-type="fig">Figure 3</xref> graphically shows their distribution for the studies examined in this paper.</p>
          <table-wrap position="float" id="table4">
            <label>Table 4</label>
            <caption>
              <p>Studies that used sensors in each upper limb location.</p>
            </caption>
            <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
              <col width="371"/>
              <col width="383"/>
              <col width="246"/>
              <thead>
                <tr valign="top">
                  <td>Location</td>
                  <td>Studies</td>
                  <td>Number of studies</td>
                </tr>
              </thead>
              <tbody>
                <tr valign="top">
                  <td>Scapula</td>
                  <td>[<xref ref-type="bibr" rid="ref21">21</xref>,<xref ref-type="bibr" rid="ref28">28</xref>]</td>
                  <td>2</td>
                </tr>
                <tr valign="top">
                  <td>Torso</td>
                  <td>[<xref ref-type="bibr" rid="ref19">19</xref>,<xref ref-type="bibr" rid="ref24">24</xref>,<xref ref-type="bibr" rid="ref28">28</xref>]</td>
                  <td>3</td>
                </tr>
                <tr valign="top">
                  <td>Sternum</td>
                  <td>[<xref ref-type="bibr" rid="ref14">14</xref>,<xref ref-type="bibr" rid="ref20">20</xref>,<xref ref-type="bibr" rid="ref21">21</xref>,<xref ref-type="bibr" rid="ref34">34</xref>]</td>
                  <td>4</td>
                </tr>
                <tr valign="top">
                  <td>Shoulder</td>
                  <td>[<xref ref-type="bibr" rid="ref21">21</xref>,<xref ref-type="bibr" rid="ref24">24</xref>,<xref ref-type="bibr" rid="ref35">35</xref>]</td>
                  <td>3</td>
                </tr>
                <tr valign="top">
                  <td>Upper arm</td>
                  <td>[<xref ref-type="bibr" rid="ref13">13</xref>,<xref ref-type="bibr" rid="ref14">14</xref>,<xref ref-type="bibr" rid="ref18">18</xref>-<xref ref-type="bibr" rid="ref21">21</xref>,<xref ref-type="bibr" rid="ref23">23</xref>,<xref ref-type="bibr" rid="ref26">26</xref>,<xref ref-type="bibr" rid="ref27">27</xref>,<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref34">34</xref>,<xref ref-type="bibr" rid="ref35">35</xref>,<xref ref-type="bibr" rid="ref39">39</xref>]</td>
                  <td>13</td>
                </tr>
                <tr valign="top">
                  <td>Forearm</td>
                  <td>[<xref ref-type="bibr" rid="ref14">14</xref>,<xref ref-type="bibr" rid="ref18">18</xref>-<xref ref-type="bibr" rid="ref21">21</xref>,<xref ref-type="bibr" rid="ref23">23</xref>,<xref ref-type="bibr" rid="ref27">27</xref>,<xref ref-type="bibr" rid="ref33">33</xref>,<xref ref-type="bibr" rid="ref34">34</xref>,<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref37">37</xref>,<xref ref-type="bibr" rid="ref39">39</xref>]</td>
                  <td>13</td>
                </tr>
                <tr valign="top">
                  <td>Wrist</td>
                  <td>[<xref ref-type="bibr" rid="ref14">14</xref>,<xref ref-type="bibr" rid="ref16">16</xref>-<xref ref-type="bibr" rid="ref18">18</xref>,<xref ref-type="bibr" rid="ref20">20</xref>,<xref ref-type="bibr" rid="ref22">22</xref>,<xref ref-type="bibr" rid="ref23">23</xref>,<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref26">26</xref>,<xref ref-type="bibr" rid="ref29">29</xref>,<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref35">35</xref>]</td>
                  <td>12</td>
                </tr>
                <tr valign="top">
                  <td>Hand</td>
                  <td>[<xref ref-type="bibr" rid="ref15">15</xref>,<xref ref-type="bibr" rid="ref16">16</xref>,<xref ref-type="bibr" rid="ref20">20</xref>,<xref ref-type="bibr" rid="ref21">21</xref>,<xref ref-type="bibr" rid="ref23">23</xref>,<xref ref-type="bibr" rid="ref30">30</xref>,<xref ref-type="bibr" rid="ref32">32</xref>,<xref ref-type="bibr" rid="ref37">37</xref>]</td>
                  <td>8</td>
                </tr>
                <tr valign="top">
                  <td>Thumb</td>
                  <td>[<xref ref-type="bibr" rid="ref28">28</xref>,<xref ref-type="bibr" rid="ref30">30</xref>,<xref ref-type="bibr" rid="ref32">32</xref>]</td>
                  <td>3</td>
                </tr>
              </tbody>
            </table>
          </table-wrap>
          <fig id="figure3" position="float">
            <label>Figure 3</label>
            <caption>
              <p>Infograph of sensor placement. This model summarizes the placement of sensors on the upper body; however, the overall number of sensors or whether they are placed on the right or left hand has not been considered. DOF: degrees of freedom; EMG: electromyography; GYS: graphene thin-film yarn sensor; IMU: inertial measurement unit; MMG: mechanomyography.</p>
            </caption>
            <graphic xlink:href="jmir_v26i1e51994_fig3.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
          </fig>
          <p>Among the 27 studies, 13 [<xref ref-type="bibr" rid="ref13">13</xref>,<xref ref-type="bibr" rid="ref14">14</xref>,<xref ref-type="bibr" rid="ref18">18</xref>-<xref ref-type="bibr" rid="ref21">21</xref>,<xref ref-type="bibr" rid="ref23">23</xref>,<xref ref-type="bibr" rid="ref26">26</xref>,<xref ref-type="bibr" rid="ref27">27</xref>,<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref34">34</xref>,<xref ref-type="bibr" rid="ref35">35</xref>,<xref ref-type="bibr" rid="ref39">39</xref>] involved sensor placement in the upper arm, 12 [<xref ref-type="bibr" rid="ref14">14</xref>,<xref ref-type="bibr" rid="ref16">16</xref>-<xref ref-type="bibr" rid="ref18">18</xref>,<xref ref-type="bibr" rid="ref20">20</xref>,<xref ref-type="bibr" rid="ref22">22</xref>,<xref ref-type="bibr" rid="ref23">23</xref>,<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref26">26</xref>,<xref ref-type="bibr" rid="ref29">29</xref>,<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref35">35</xref>] involved placement on the wrist, and 13 [<xref ref-type="bibr" rid="ref14">14</xref>,<xref ref-type="bibr" rid="ref18">18</xref>-<xref ref-type="bibr" rid="ref21">21</xref>,<xref ref-type="bibr" rid="ref23">23</xref>,<xref ref-type="bibr" rid="ref27">27</xref>,<xref ref-type="bibr" rid="ref33">33</xref>,<xref ref-type="bibr" rid="ref34">34</xref>,<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref37">37</xref>,<xref ref-type="bibr" rid="ref39">39</xref>] involved placement on the forearm. Many studies focused on finger movement monitoring. Sensors were placed on the hand in 8 studies [<xref ref-type="bibr" rid="ref15">15</xref>,<xref ref-type="bibr" rid="ref16">16</xref>,<xref ref-type="bibr" rid="ref20">20</xref>,<xref ref-type="bibr" rid="ref21">21</xref>,<xref ref-type="bibr" rid="ref23">23</xref>,<xref ref-type="bibr" rid="ref30">30</xref>,<xref ref-type="bibr" rid="ref32">32</xref>,<xref ref-type="bibr" rid="ref37">37</xref>], on the thumb in 3 studies [<xref ref-type="bibr" rid="ref28">28</xref>,<xref ref-type="bibr" rid="ref30">30</xref>,<xref ref-type="bibr" rid="ref32">32</xref>], and on the shoulder in 3 studies [<xref ref-type="bibr" rid="ref21">21</xref>,<xref ref-type="bibr" rid="ref24">24</xref>,<xref ref-type="bibr" rid="ref35">35</xref>]. In some cases, complex body posture and position were monitored. Sensors were placed at the sternum in 4 papers [<xref ref-type="bibr" rid="ref14">14</xref>,<xref ref-type="bibr" rid="ref20">20</xref>,<xref ref-type="bibr" rid="ref21">21</xref>,<xref ref-type="bibr" rid="ref34">34</xref>], at the torso in 3 papers [<xref ref-type="bibr" rid="ref19">19</xref>,<xref ref-type="bibr" rid="ref24">24</xref>,<xref ref-type="bibr" rid="ref28">28</xref>], and at the scapula in 2 papers [<xref ref-type="bibr" rid="ref21">21</xref>,<xref ref-type="bibr" rid="ref28">28</xref>].</p>
        </sec>
        <sec>
          <title>Placement Method and Feasibility of Sensors</title>
          <p>One of the key factors considered for the development of upper limb wearable devices is the feasibility and wearability of the sensors, as in some cases, long-term monitoring is required. Consequently, the design of each system must be examined because it can greatly influence the feasibility of the system. From the reviewed papers, wearable systems can be classified into 4 categories, according to the attachment method of the sensors: (1) hook and loop straps (Velcro straps) and fastened straps; (2) bands; (3) adhesive bonding; and (4) other methods.</p>
          <p>With regard to the methods used for placing the sensors, 13 out of the 27 studies [<xref ref-type="bibr" rid="ref14">14</xref>,<xref ref-type="bibr" rid="ref16">16</xref>,<xref ref-type="bibr" rid="ref19">19</xref>,<xref ref-type="bibr" rid="ref21">21</xref>,<xref ref-type="bibr" rid="ref24">24</xref>-<xref ref-type="bibr" rid="ref28">28</xref>,<xref ref-type="bibr" rid="ref30">30</xref>,<xref ref-type="bibr" rid="ref34">34</xref>,<xref ref-type="bibr" rid="ref35">35</xref>,<xref ref-type="bibr" rid="ref39">39</xref>] selected hook and loop straps. More specifically, 4 studies [<xref ref-type="bibr" rid="ref26">26</xref>,<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref34">34</xref>,<xref ref-type="bibr" rid="ref39">39</xref>] used only a Velcro strap, which is a fastener that adheres to itself. Straps are generally a preferred type of placement method as they can be placed in convenient places on the arm [<xref ref-type="bibr" rid="ref27">27</xref>] and they are simple, lightweight, and easy to use [<xref ref-type="bibr" rid="ref25">25</xref>]. Clip-on straps have also been developed, which are flexible, and they allow inertial sensors to be placed on the fingers [<xref ref-type="bibr" rid="ref16">16</xref>]. Furthermore, 5 studies [<xref ref-type="bibr" rid="ref19">19</xref>,<xref ref-type="bibr" rid="ref21">21</xref>,<xref ref-type="bibr" rid="ref24">24</xref>,<xref ref-type="bibr" rid="ref28">28</xref>,<xref ref-type="bibr" rid="ref35">35</xref>] used a combination of hook and loop straps. Medical tape with 3D-printed flexible straps [<xref ref-type="bibr" rid="ref21">21</xref>] or Velcro straps [<xref ref-type="bibr" rid="ref35">35</xref>] were designed for upper limb assessment and rehabilitation of stroke patients, respectively. The former application was characterized by participants as being “comfortable to wear;” however, 3 of them reported impedance to grasp because of the finger sensors. In the latter, the design was a major issue as there is still work in the development of the sensors and their alignment. Straps along with direct winding of sensors in the armband [<xref ref-type="bibr" rid="ref19">19</xref>] were also used as a method of placement; however, there is no discussion about the feasibility of the system. Another way to improve the feasibility of wearability is by designing a vest where different garment parts are attached with Velcro straps [<xref ref-type="bibr" rid="ref24">24</xref>]. A zipped vest of soft material was developed, which makes it easier for patients to put on and take off. The precision of the sensor is guaranteed by a predefined position, and it is sewn by coated conductive yarn on a soft elastic strap with a Velcro strap fastened at the end. Overall, this system is perceived as highly usable, and the patients were motivated to train with it. Similarly, a garment embedded with smart textiles, conductive points, yarns, and sensors attached with elastic Velcro straps was also introduced [<xref ref-type="bibr" rid="ref28">28</xref>]. This system is adjustable and more precise as sensors are placed in different positions, and it was rated as having high usability by users because it resembles everyday clothing in appearance and comfort while accurately tracking posture. Finally, flexible resin straps were also used [<xref ref-type="bibr" rid="ref14">14</xref>] for attaching the housing cases of the sensors; however, the wearability of the system was not characterized.</p>
          <p>Stretchable bands have also been designed [<xref ref-type="bibr" rid="ref18">18</xref>] as they provide convenience and comfort around the arm without disturbing the subject’s movement [<xref ref-type="bibr" rid="ref20">20</xref>]. Furthermore, for hand and finger tracking, wristbands and rings were developed [<xref ref-type="bibr" rid="ref16">16</xref>], and they were attached to the wrist and finger, respectively; however, the feasibility of the application was not discussed. For tracking the forearm, a study [<xref ref-type="bibr" rid="ref36">36</xref>] used an armband to secure the IMU position; thus, the surface EMG acquisition remained the same for all patients. Feasibility was also not examined for this system.</p>
          <p>Another method of attaching sensors to the body is adhesive bonding [<xref ref-type="bibr" rid="ref15">15</xref>,<xref ref-type="bibr" rid="ref23">23</xref>,<xref ref-type="bibr" rid="ref32">32</xref>,<xref ref-type="bibr" rid="ref37">37</xref>]. In this case, conductive sensors are included in the fabric and support wearable technologies. Their main function is to sense the physical movement of the arm and then transform it into electrical signals. Assessment of hand movement is necessary when evaluating hand function, and many glove-sensing systems lack rotational observability, hand orientation estimation, and user customization. Sensors can be mounted on a double-sided adhesive tape [<xref ref-type="bibr" rid="ref23">23</xref>] as well as on a polyamide/elastane-fabricated glove [<xref ref-type="bibr" rid="ref32">32</xref>], which consists of multiple printed circuit board strings that are attached to each finger segment. However, the feasibility of the system was not specified. Skin-friendly tape that attaches individual sensor strips adhesively to the finger segments and a silicon fixture that attaches the base unit of the system to the back of the hand make the system compact and portable. The sensor strips can be removed and replaced, thus increasing the flexibility in different therapy settings and different hand sizes, which makes the system more practical and easier to maintain [<xref ref-type="bibr" rid="ref37">37</xref>]. A waterborne adhesive is an alternative method of attaching sensors to the hands as the system is fully integrated, but the result is not considered very feasible [<xref ref-type="bibr" rid="ref15">15</xref>].</p>
          <p>Regular elastic fabrics have also been used [<xref ref-type="bibr" rid="ref33">33</xref>], where a prototype provided an acceptable comfort level and could be adapted to target users with different figures. A commercial elastane-based fitness shirt with elasticity was also used as a “vest,” where sensors were attached by polychloroprene-based adhesive [<xref ref-type="bibr" rid="ref38">38</xref>]. Comfort and elasticity were the key requirements for the base shirt to conform with the shape of the body of the user.</p>
          <p>From the papers included in this review, only 1 study was conducted by using direct winding (the only placement method for attaching sensors to the body) [<xref ref-type="bibr" rid="ref13">13</xref>]. GYSs were attached by direct winding on varied portions of the human body for monitoring different movements such as finger bending and muscle contraction and relaxation. A new direct-wearing mode, where the GYS can be directly attached to the skin, was introduced, which resulted in the improvement of sensing accuracy. Moreover, flexible fabric straps made of Lycra have been partially sewn on a glove structure [<xref ref-type="bibr" rid="ref31">31</xref>] to fix the sensor in an optimal position. The feasibility and flexibility of this application are not discussed, and thus, the usability of the system cannot be concluded. A wearable device for tracking the daily use of the wrist and a finger was developed by designing a watch-like enclosure that is worn on the wrist with a small neodymium magnetic ring on the index finger [<xref ref-type="bibr" rid="ref29">29</xref>]. This design is described as “nonobtrusive” as the ring provides a reliable wireless signal without a power source, and thus, the need for bulky wiring or a battery is eliminated. Because of its design, the “Manumeter” is described as “socially acceptable,” and it can be worn for long durations. In a more recent study [<xref ref-type="bibr" rid="ref22">22</xref>], a newer version of the “Manumeter” was developed, where a jewelry-like device was fastened to the wrist with a band to monitor its movement. For finger movement, an ipsilateral finger ring was placed on the index finger. However, feasibility was not discussed.</p>
        </sec>
      </sec>
      <sec>
        <title>Signal Processing Techniques and Extracted Features</title>
        <p>Wearable upper limb devices provide important information about limb motion through motion analysis. Different signal processing techniques were used, and features were extracted to provide feedback to end users or therapists for better data assessment and interpretation of movement.</p>
        <p>Signal processing is essential for such devices to reduce noise signals, transform data, and extract meaningful motion features. A variety of filters are used depending on the data provided by the sensors and the desired output of the system. In 13 studies [<xref ref-type="bibr" rid="ref14">14</xref>,<xref ref-type="bibr" rid="ref16">16</xref>-<xref ref-type="bibr" rid="ref22">22</xref>,<xref ref-type="bibr" rid="ref26">26</xref>,<xref ref-type="bibr" rid="ref29">29</xref>,<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref32">32</xref>,<xref ref-type="bibr" rid="ref35">35</xref>], filters were used to remove noise from sensor signals. More specifically, the Kalman filter was used in 2 studies [<xref ref-type="bibr" rid="ref20">20</xref>,<xref ref-type="bibr" rid="ref32">32</xref>], which is an algorithm that uses observed measurements over time to produce estimated unknown variables that tend to be more accurate by estimating a joint probability distribution over the variable of each timeframe.</p>
        <p>In 3 studies [<xref ref-type="bibr" rid="ref18">18</xref>,<xref ref-type="bibr" rid="ref21">21</xref>,<xref ref-type="bibr" rid="ref32">32</xref>], the Butterworth filter was used to minimize low-frequency noise and high-frequency interferences. Another method to extract data from upper limb devices involves the infinite impulse response filter (IIR) [<xref ref-type="bibr" rid="ref14">14</xref>,<xref ref-type="bibr" rid="ref26">26</xref>]. This filter is digital with infinite impulse response and can be designed as a low-pass or high-pass filter. The Madgwick filter is an algorithm that reduces integration errors by the magnetometer and accelerometer, and it was used in 1 study [<xref ref-type="bibr" rid="ref16">16</xref>]. A combination of 2 of the aforementioned filters was implemented in 1 study [<xref ref-type="bibr" rid="ref21">21</xref>]. The accelerometer and gyroscope data were low-pass filtered using the Butterworth filter and then passed through the Madgwick filter to integrate the drift of the angular velocity. A complementary filter was implemented in 1 study [<xref ref-type="bibr" rid="ref31">31</xref>] to reduce the integration drift by providing correct data on the orientation and position of each upper limb segment. More recently, research has been conducted on machine learning (ML) techniques to assist with predicting motion and improving tracking accuracy. For example, the Block Sparse Bayesian Learning (BSBL) algorithm was used in 1 study to reconstruct the accelerometer signal from compressed data [<xref ref-type="bibr" rid="ref27">27</xref>]. Little et al [<xref ref-type="bibr" rid="ref19">19</xref>], on the other hand, compared 10 different ML algorithms to predict angle trajectories through the fusion of physiological and kinematic features.</p>
        <p>Another important feature of wearable devices is the sampling rates of the sensors, as they determine the quality of the captured data, providing a better understanding of upper limb motion. High sampling rates provide more precise data acquisition; however, battery life is significantly reduced as power consumption is increased. More specifically, in the revised studies, the smallest sampling rate was mentioned in the research conducted by Tolvanen et al [<xref ref-type="bibr" rid="ref23">23</xref>], where a pressure sensitivity test for light finger touch by a stretch sensor was performed. In contrast, the highest sampling rate was at 2000 Hz in a paper by Pregnolato et al [<xref ref-type="bibr" rid="ref36">36</xref>], where hand movements of stroke patients for rehabilitation were captured by a 9-DOF IMU with a surface EMG sensor. While both studies provide valuable insights into their respective applications, the battery life was not mentioned. With regard to the battery life, the shortest battery duration was observed in a study by Gu et al [<xref ref-type="bibr" rid="ref15">15</xref>], where 10 hydrogel-elastomer hybrid ionic sensors were used to capture hand motion, joint bending, hand posture, and gesture. The battery life in this study was 1-2 hours, with an approximate sampling rate of 333.33 Hz, attributed to a 3.3-V rechargeable Li-ion battery. In contrast, the longest battery life was reported by Friedman et al [<xref ref-type="bibr" rid="ref29">29</xref>], with a duration of 21.5 hours. Power was delivered to 2 triaxial magnetometers and 1 accelerometer to monitor wrist and hand movements, and the sensors were powered by a 3.7-V 450-mAh lithium polymer battery.</p>
        <p>The relationship between battery size and sampling rate is crucial as it can affect the efficiency of the wearable sensors. Specifically, in the study conducted by Lee et al [<xref ref-type="bibr" rid="ref17">17</xref>], a 170-mAh battery (sized 1-2 cm) was used to power an accelerometer with a sampling rate of 67 Hz, and the battery life was approximately 6 hours. In contrast, Wang et al [<xref ref-type="bibr" rid="ref24">24</xref>] employed a larger 10-cm 3-V battery to power two 9-DOF IMUs with a sampling rate of 50 Hz. This variety of sampling rates and data acquisition reflects the diverse design choices between consumption and device portability in wearable sensor technology.</p>
      </sec>
      <sec>
        <title>Type of Feedback and Accuracy of the System</title>
        <p>Feedback is a key feature of the rehabilitation process and motion tracking as it provides important and meaningful information to therapists to interpret the performance of the system. Moreover, it plays an important role in informing patients of their progress, which leads to better recovery chances. The majority of studies (23/27) [<xref ref-type="bibr" rid="ref13">13</xref>-<xref ref-type="bibr" rid="ref23">23</xref>,<xref ref-type="bibr" rid="ref25">25</xref>-<xref ref-type="bibr" rid="ref27">27</xref>,<xref ref-type="bibr" rid="ref29">29</xref>-<xref ref-type="bibr" rid="ref35">35</xref>,<xref ref-type="bibr" rid="ref37">37</xref>,<xref ref-type="bibr" rid="ref38">38</xref>] used visual feedback. Three studies provided visual and auditory information [<xref ref-type="bibr" rid="ref24">24</xref>,<xref ref-type="bibr" rid="ref36">36</xref>] and haptic feedback along with visual and auditory information [<xref ref-type="bibr" rid="ref24">24</xref>,<xref ref-type="bibr" rid="ref28">28</xref>], and 1 study [<xref ref-type="bibr" rid="ref39">39</xref>] provided only haptic feedback.</p>
        <p>More specifically, visual feedback provides therapists and users with more precise information about their tasks and training instructions to achieve the desired position through direct visual analysis of the movement. Haptic feedback is provided by vibrotactile actuators, and small transducers are designed to optimize skin response to vibration. The vibrotactile actuators must have a minimum critical distance for their vibration to be identifiable, and the subjects of the experiment had to rely exclusively on it to accurately rehabilitate their posture and eventually regain their lost muscular abilities. Wearable devices that used a combination of feedback approaches (visual, audio, and haptic) provided an objective outcome that contributed to increasing the effectiveness of training. Moreover, these approaches provide support to therapists, giving them additional information about the patients’ motions, and lastly, the quality of training is improved by detailed feedback signals.</p>
        <p>Accuracy of system measurements is necessary for the effectiveness of proposed wearable devices as it plays a vital role in the interpretation of output data and the extraction of user features. Consequently, feedback should be quick enough to improve the operator’s performance in terms of reducing mental effort and informing therapists about movement characteristics. One of the most common ways to present the accuracy of the system and evaluate position and velocity based on a kinematic model is through the calculation of the mean error between the bending joint angle of the user and the proposed validated algorithm with good accuracy, which is used as a reference, under different speeds and magnitudes [<xref ref-type="bibr" rid="ref14">14</xref>,<xref ref-type="bibr" rid="ref16">16</xref>,<xref ref-type="bibr" rid="ref17">17</xref>,<xref ref-type="bibr" rid="ref19">19</xref>,<xref ref-type="bibr" rid="ref22">22</xref>,<xref ref-type="bibr" rid="ref24">24</xref>,<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref27">27</xref>,<xref ref-type="bibr" rid="ref29">29</xref>-<xref ref-type="bibr" rid="ref37">37</xref>]. Moreover, a statistical analysis is conducted by calculating the “root mean square deviation” (RMSD) or “root mean square error” (RMSE), correlation coefficient (CC), mean absolute error (MAE), and <italic>P</italic> value. In some papers, accuracy was either not measured or the circumstances under which accuracy was calculated were not mentioned [<xref ref-type="bibr" rid="ref13">13</xref>,<xref ref-type="bibr" rid="ref15">15</xref>,<xref ref-type="bibr" rid="ref18">18</xref>,<xref ref-type="bibr" rid="ref20">20</xref>,<xref ref-type="bibr" rid="ref21">21</xref>,<xref ref-type="bibr" rid="ref23">23</xref>,<xref ref-type="bibr" rid="ref26">26</xref>,<xref ref-type="bibr" rid="ref28">28</xref>,<xref ref-type="bibr" rid="ref35">35</xref>,<xref ref-type="bibr" rid="ref38">38</xref>,<xref ref-type="bibr" rid="ref39">39</xref>].</p>
      </sec>
    </sec>
    <sec sec-type="discussion">
      <title>Discussion</title>
      <sec>
        <title>Principal Findings</title>
        <p>This paper provides a systematic literature review of upper limb wearable device technologies that were developed in the past decade. The screening of papers from 4 different electronic libraries yielded a total of 27 relevant papers that were included for analysis. The papers were classified into 2 major categories, according to the purpose of the study: clinical motion tracking and rehabilitation. The analysis of the findings suggests that upper limb motion is most often tracked using inertial sensors owing to their accuracy, compact size, and effectiveness in assessing range of motion (ROM). Advanced data processing techniques, such as Kalman and Madgwick filters, were used for data fusion, ensuring data accuracy. One of the key elements of wearable technologies is usability, which can be affected by how wearables are placed on a user, their form factor, and their energy consumption. Even though most studies used straps for placing sensors, the other characteristics have greater variability, with no clear consensus among the research community.</p>
        <p>The papers were categorized according to the type of study (controlled and uncontrolled). Most of them were uncontrolled studies, which may lead to bias because of the absence of randomly selected control groups and a comparison between them.</p>
        <p>The goal of upper limb wearable devices is to provide assistance to therapists and researchers through either monitoring upper limb function for clinical assessment or aiding rehabilitation training and reducing the recovery time [<xref ref-type="bibr" rid="ref40">40</xref>]. Overall, the developed wearable devices can positively influence the motivation of users, while in the case of rehabilitation, patients can undergo treatment at home by aiming for a high level of independence [<xref ref-type="bibr" rid="ref41">41</xref>].</p>
        <p>Various sensing technologies were used for tracking upper limb motion. Inertial sensors tend to be the most used sensors as they are used to estimate joint angles of the upper limbs. These technologies provide data accuracy, and because of their size, they are used to monitor and provide feedback to patients and therapists on ROM and rehabilitation performance. However, the placement method needs to be considered owing to its essential role in the ROM assessment, as the interpretation of data influences the development of rehabilitation treatment. Moreover, a flexible and well-fitted design can improve signal quality and reduce measurement noise [<xref ref-type="bibr" rid="ref42">42</xref>]. Consequently, the majority of devices were attached to the body with straps (mostly Velcro straps), as they provide flexibility and great strength (eliminating data bias) and require low maintenance. The hold that Velcro straps provide can be generally characterized as “firm.” Although this placement method is easy and noninvasive [<xref ref-type="bibr" rid="ref39">39</xref>] and there is no need for external cameras, emitters, or markers [<xref ref-type="bibr" rid="ref31">31</xref>], the feasibility of the system is not guaranteed for an extended period [<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref39">39</xref>]. Similarly, clip-on straps can make the system modular in many aspects. This design can be adopted regardless of hand dimensions and the presence of deformities or inflammation. These straps are manufactured by using a stretchable and flexible material that yields extra comfort and causes minimum disruptions to movement [<xref ref-type="bibr" rid="ref16">16</xref>].</p>
        <p>The placement of wearable sensors significantly impacts their performance, user acceptance, and engineering demands. As sensor technology progresses from wearable to implantable and ingestible forms, challenges arise across regulatory, technical, and translational domains. Misplacement or misalignment of wearable sensors can reduce classifier accuracy; however, some approaches have maintained precision (97%) and recall (98%) at high levels during movement classification [<xref ref-type="bibr" rid="ref7">7</xref>,<xref ref-type="bibr" rid="ref9">9</xref>].</p>
        <p>Despite the utility of straps, challenges remain in optimal sensor placement for maintaining user comfort and mobility and managing interference between sensors. Overcoming these challenges includes performing comprehensive user studies and data analyses to determine the best sensor placement, as well as designing an ergonomic and adaptable sensor housing for enhancing user comfort [<xref ref-type="bibr" rid="ref43">43</xref>]. Thus, the ergonomic aspects of the system, such as dimension, weight, and undesirable contact, should be considered to accommodate various hand sizes and deformations [<xref ref-type="bibr" rid="ref16">16</xref>]. Recent innovations have focused on achieving body compliance, ensuring comfort for the wearer, and maintaining accurate sensing performance [<xref ref-type="bibr" rid="ref43">43</xref>].</p>
        <p>Furthermore, some studies used smart textiles or e-textiles with embedded sensors as the sensing technology, which provided great feasibility regarding wearability. The use of textiles in health care and wellness applications has increased over the last few years and is expected to grow further in the future [<xref ref-type="bibr" rid="ref41">41</xref>]. The primary benefit of using textile-based electrodes is that there is no direct contact with the skin, and this prevents problems like allergy and skin irritation [<xref ref-type="bibr" rid="ref44">44</xref>]. Nevertheless, additional research needs to be conducted for integrating accuracy, improving usability, and implementing clinical validation. We expect that the benefits provided by textiles, especially related to ease of use and flexibility, and the advances in technology will make them essential for tracking motion and muscle activity and improving rehabilitation outcomes [<xref ref-type="bibr" rid="ref44">44</xref>,<xref ref-type="bibr" rid="ref45">45</xref>].</p>
        <p>Wearable devices capture upper limb motion through data acquisition and processing. The examined studies used various measurement methods to record data such as body segment posture, amount of use, and ROM. Undoubtedly, data processing is necessary for developing wearable devices as the signals captured have to be interpreted. The most common filters are Butterworth, low-pass, and band-pass, which are used to weaken potential high-frequency noise in the accelerometer and gyroscope. Moreover, Kalman, Madgwick, and complementary filters are used to fuse the sensor readings and overcome potential biomechanical constraints. These algorithms combine the sensor readings to indicate the rotation and orientation of the arm; however, they tend to require high computational power.</p>
        <p>Sampling rates across the analyzed studies varied significantly and ranged from as low as 2 Hz for pressure-sensing technologies to as high as 2000 Hz for motion-sensing applications. Balancing high sampling rates and energy efficiency remains a challenge for upper limb wearable devices, as higher rates enhance tracking precision but can reduce battery life. The wide range of rates indicates the adaptability and flexibility of the sensors used for upper limb applications, as they capture muscle movements as well as rapid motion movements with precision. However, the selection of the right battery to support the desired sampling rates remains a challenge, and there is a need for careful selection to ensure prolonged and uninterrupted data acquisition.</p>
        <p>Different techniques are being developed that aim to improve energy efficiency and extend the battery life of wearable devices. For example, compressed sensing [<xref ref-type="bibr" rid="ref46">46</xref>] allows the reduction of the sampling rate of a signal, which can then be transmitted using a compressed sparse representation and reconstructed with minimal loss compared to the original signal [<xref ref-type="bibr" rid="ref47">47</xref>,<xref ref-type="bibr" rid="ref48">48</xref>]. Another algorithm that can be used with time series data, such as motion and muscle data, and can improve energy efficiency is change point detection [<xref ref-type="bibr" rid="ref49">49</xref>]. The algorithm is used to detect the point when a signal changes and is often used to assist with action recognition [<xref ref-type="bibr" rid="ref50">50</xref>]. Therefore, by detecting the time point when a signal changes, the sampling rate can be adapted and energy consumption can be reduced during nonrelevant activities (eg, transition between motions, resting, etc) [<xref ref-type="bibr" rid="ref49">49</xref>]. At the same time, recently, research has been conducted on extending battery life through energy harvesting [<xref ref-type="bibr" rid="ref51">51</xref>]. The process relies on capturing energy either directly from the human body, including motion [<xref ref-type="bibr" rid="ref43">43</xref>], or from the environment and converting it to power.</p>
        <p>Feedback plays a crucial role in the overall system performance as it provides useful information to therapists and researchers and affects therapy outcomes by influencing motivation. Feedback is given frequently to users who are less proficient or whose posture needs to be improved. This is beneficial for future applications as users should not rely on external feedback, but instead follow their intrinsic feedback mechanics. Visual information on a computer or smartphone/tablet is usually provided, which is very useful, especially for systems that are remotely monitored. Ultimately, the main aim of feedback is to help users improve their performance while providing useful data to therapists for better information processing and future reference.</p>
        <p>The improved computation power of electronics and advances in ML algorithms have increased the use of these algorithms for not only motion trajectory prediction [<xref ref-type="bibr" rid="ref52">52</xref>] but also assessing motion quality and providing relevant feedback during rehabilitation [<xref ref-type="bibr" rid="ref53">53</xref>]. Using ML with wearable devices through Tiny Machine Learning (TinyML) has gained popularity recently; however, many challenges remain [<xref ref-type="bibr" rid="ref54">54</xref>]. Further research in this area can revolutionize the use of wearable technology in health care applications by providing greater accuracy, and improved and more personalized feedback. Feedback can also be further reinforced using haptic devices [<xref ref-type="bibr" rid="ref55">55</xref>]. However, current haptic devices can be cumbersome, and more portable devices need to be developed to make such technologies easy to use in a clinical setting [<xref ref-type="bibr" rid="ref56">56</xref>].</p>
      </sec>
      <sec>
        <title>Limitations and Conclusion</title>
        <p>In this review, an effort was made to cover studies related to upper limb wearable devices, including study purpose, sensing technology, feasibility and wearability of the system, sensor placement, methodology, and feedback received. However, because of the variety of studies conducted in this area, every aspect could not be covered, and hence, a summary was provided for aspects with relatively more research. Limitations, such as the positioning, number, and possible disruption of sensors, are challenges that need to be overcome as they affect the limb’s computed trajectory. Moreover, when a magnetometer is used, ferromagnetic materials can affect its calibration, and the data may not be transmitted with accuracy. Additionally, the lack of uniformity of battery specifications (compared to sampling rates) and sensor specifications highlights the challenges in comparisons between these characteristics and standardized data in this field. Although the studies reviewed indicated a positive influence regarding the motivation of users, more clinical trials need to be conducted, as they are important to assess the effectiveness of the system. Another limitation is the search strategy employed in this review. The search was performed in only 4 specific databases: ACM Digital Library, IEEE Xplore, PubMed, and ScienceDirect. The search may have excluded relevant papers, and some studies might have been overlooked. The low number of studies analyzed might not fully capture the diversity of the current research in the field, which limits the comprehensiveness of the review.</p>
        <p>Future studies should aim to reduce the weight and dimensions of the system and increase the sampling rate, which can facilitate quick motion tracking with high accuracy. Additionally, efforts should be made to fabricate upper limb devices that are more flexible, powerful, and compact. The progress of ML algorithms would be beneficial, particularly in IMU- and EMG-based devices, as the rehabilitation process is automatically guided in real-life settings while being able to provide remote intervention [<xref ref-type="bibr" rid="ref55">55</xref>]. Moreover, researchers should focus on the further development of feedback as it should be more adaptable and provide more options to users and therapists. In addition, long-term clinical trials are essential for establishing the effectiveness of wearable devices in real-world rehabilitation settings. These trials should focus on larger and more diverse patient groups to better establish the system’s efficacy. Moreover, in broader health care frameworks, standardized protocols and consistent measurement methods should be developed to ensure the results are accurately compared, thus ensuring the reliability of the system. Behavioral measurements are also important, especially in training sessions. In conclusion, future research should focus on integrating sensors and improving usability and feasibility as upper limb wearable devices are predictably becoming powerful tools, enabling innovative rehabilitation treatments while improving the quality of health care.</p>
      </sec>
    </sec>
  </body>
  <back>
    <app-group>
      <supplementary-material id="app1">
        <label>Multimedia Appendix 1</label>
        <p>PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) checklist.</p>
        <media xlink:href="jmir_v26i1e51994_app1.pdf" xlink:title="PDF File  (Adobe PDF File), 550 KB"/>
      </supplementary-material>
    </app-group>
    <glossary>
      <title>Abbreviations</title>
      <def-list>
        <def-item>
          <term id="abb1">DOF</term>
          <def>
            <p>degrees of freedom</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb2">EMG</term>
          <def>
            <p>electromyography</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb3">GYS</term>
          <def>
            <p>graphene thin-film yarn sensor</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb4">IMU</term>
          <def>
            <p>inertial measurement unit</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb5">ML</term>
          <def>
            <p>machine learning</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb6">MMG</term>
          <def>
            <p>mechanomyography</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb7">ROM</term>
          <def>
            <p>range of motion</p>
          </def>
        </def-item>
      </def-list>
    </glossary>
    <ack>
      <p>This project has received funding from the European Union’s Horizon 2020 Research and Innovation Programme under grant agreement number 739578 and the Government of the Republic of Cyprus through the Deputy Ministry of Research, Innovation and Digital Policy.</p>
    </ack>
    <notes>
      <sec>
        <title>Data Availability</title>
        <p>All data generated or analyzed during this study are included in the published articles mentioned in the review.</p>
      </sec>
    </notes>
    <fn-group>
      <fn fn-type="con">
        <p>EK contributed to data collection, data analysis, data interpretation, and drafting the article. MM contributed to conception of the work, data collection, data analysis, data interpretation, and critical revision of the article. FF contributed to drafting and revising the article. PP contributed to data collection and analysis. KN contributed to critical revision of the article. CP contributed to critical revision of the article.</p>
      </fn>
      <fn fn-type="conflict">
        <p>None declared.</p>
      </fn>
    </fn-group>
    <ref-list>
      <ref id="ref1">
        <label>1</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Hewitt</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Sephton</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Yeowell</surname>
              <given-names>G</given-names>
            </name>
          </person-group>
          <article-title>The effectiveness of digital health interventions in the management of musculoskeletal conditions: systematic literature review</article-title>
          <source>J Med Internet Res</source>
          <year>2020</year>
          <month>06</month>
          <day>05</day>
          <volume>22</volume>
          <issue>6</issue>
          <fpage>e15617</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.jmir.org/2020/6/e15617/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/15617</pub-id>
          <pub-id pub-id-type="medline">32501277</pub-id>
          <pub-id pub-id-type="pii">v22i6e15617</pub-id>
          <pub-id pub-id-type="pmcid">PMC7305565</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref2">
        <label>2</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Balogh</surname>
              <given-names>I</given-names>
            </name>
            <name name-style="western">
              <surname>Arvidsson</surname>
              <given-names>I</given-names>
            </name>
            <name name-style="western">
              <surname>Björk</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Hansson</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Ohlsson</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Skerfving</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Nordander</surname>
              <given-names>C</given-names>
            </name>
          </person-group>
          <article-title>Work-related neck and upper limb disorders - quantitative exposure-response relationships adjusted for personal characteristics and psychosocial conditions</article-title>
          <source>BMC Musculoskelet Disord</source>
          <year>2019</year>
          <month>04</month>
          <day>01</day>
          <volume>20</volume>
          <issue>1</issue>
          <fpage>139</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://bmcmusculoskeletdisord.biomedcentral.com/articles/10.1186/s12891-019-2491-6"/>
          </comment>
          <pub-id pub-id-type="doi">10.1186/s12891-019-2491-6</pub-id>
          <pub-id pub-id-type="medline">30935374</pub-id>
          <pub-id pub-id-type="pii">10.1186/s12891-019-2491-6</pub-id>
          <pub-id pub-id-type="pmcid">PMC6444852</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref3">
        <label>3</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Srinivasan</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Mathiassen</surname>
              <given-names>SE</given-names>
            </name>
          </person-group>
          <article-title>Motor variability in occupational health and performance</article-title>
          <source>Clin Biomech (Bristol)</source>
          <year>2012</year>
          <month>12</month>
          <volume>27</volume>
          <issue>10</issue>
          <fpage>979</fpage>
          <lpage>93</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://linkinghub.elsevier.com/retrieve/pii/S0268-0033(12)00181-7"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/j.clinbiomech.2012.08.007</pub-id>
          <pub-id pub-id-type="medline">22954427</pub-id>
          <pub-id pub-id-type="pii">S0268-0033(12)00181-7</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref4">
        <label>4</label>
        <nlm-citation citation-type="confproc">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Orfanidis</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Darwich</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Cheong</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Fafoutis</surname>
              <given-names>X</given-names>
            </name>
          </person-group>
          <article-title>Monitoring neurological disorders with AI-enabled wearable systems</article-title>
          <source>DigiBiom '22: Proceedings of the 2022 Workshop on Emerging Devices for Digital Biomarkers</source>
          <year>2022</year>
          <conf-name>20th Annual International Conference on Mobile Systems, Applications and Services</conf-name>
          <conf-date>July 1, 2022</conf-date>
          <conf-loc>Portland, Oregon</conf-loc>
          <pub-id pub-id-type="doi">10.1145/3539494.3542755</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref5">
        <label>5</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Maciejasz</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Eschweiler</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Gerlach-Hahn</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Jansen-Troy</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Leonhardt</surname>
              <given-names>S</given-names>
            </name>
          </person-group>
          <article-title>A survey on robotic devices for upper limb rehabilitation</article-title>
          <source>J NeuroEngineering Rehabil</source>
          <year>2014</year>
          <month>01</month>
          <day>09</day>
          <volume>11</volume>
          <issue>1</issue>
          <fpage>3</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="http://www.jneuroengrehab.com/content/11/1/3"/>
          </comment>
          <pub-id pub-id-type="doi">10.1186/1743-0003-11-3</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref6">
        <label>6</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Vélez-Guerrero</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Callejas-Cuervo</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Mazzoleni</surname>
              <given-names>S</given-names>
            </name>
          </person-group>
          <article-title>Artificial intelligence-based wearable robotic exoskeletons for upper limb rehabilitation: a review</article-title>
          <source>Sensors (Basel)</source>
          <year>2021</year>
          <month>03</month>
          <day>18</day>
          <volume>21</volume>
          <issue>6</issue>
          <fpage>2146</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.mdpi.com/resolver?pii=s21062146"/>
          </comment>
          <pub-id pub-id-type="doi">10.3390/s21062146</pub-id>
          <pub-id pub-id-type="medline">33803911</pub-id>
          <pub-id pub-id-type="pii">s21062146</pub-id>
          <pub-id pub-id-type="pmcid">PMC8003246</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref7">
        <label>7</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Maceira-Elvira</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Popa</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Schmid</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Hummel</surname>
              <given-names>FC</given-names>
            </name>
          </person-group>
          <article-title>Wearable technology in stroke rehabilitation: towards improved diagnosis and treatment of upper-limb motor impairment</article-title>
          <source>J Neuroeng Rehabil</source>
          <year>2019</year>
          <month>11</month>
          <day>19</day>
          <volume>16</volume>
          <issue>1</issue>
          <fpage>142</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://jneuroengrehab.biomedcentral.com/articles/10.1186/s12984-019-0612-y"/>
          </comment>
          <pub-id pub-id-type="doi">10.1186/s12984-019-0612-y</pub-id>
          <pub-id pub-id-type="medline">31744553</pub-id>
          <pub-id pub-id-type="pii">10.1186/s12984-019-0612-y</pub-id>
          <pub-id pub-id-type="pmcid">PMC6862815</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref8">
        <label>8</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>van Ommeren</surname>
              <given-names>AL</given-names>
            </name>
            <name name-style="western">
              <surname>Smulders</surname>
              <given-names>LC</given-names>
            </name>
            <name name-style="western">
              <surname>Prange-Lasonder</surname>
              <given-names>GB</given-names>
            </name>
            <name name-style="western">
              <surname>Buurke</surname>
              <given-names>JH</given-names>
            </name>
            <name name-style="western">
              <surname>Veltink</surname>
              <given-names>PH</given-names>
            </name>
            <name name-style="western">
              <surname>Rietman</surname>
              <given-names>JS</given-names>
            </name>
          </person-group>
          <article-title>Assistive technology for the upper extremities after stroke: systematic review of users' needs</article-title>
          <source>JMIR Rehabil Assist Technol</source>
          <year>2018</year>
          <month>11</month>
          <day>29</day>
          <volume>5</volume>
          <issue>2</issue>
          <fpage>e10510</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://rehab.jmir.org/2018/2/e10510/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/10510</pub-id>
          <pub-id pub-id-type="medline">30497993</pub-id>
          <pub-id pub-id-type="pii">v5i2e10510</pub-id>
          <pub-id pub-id-type="pmcid">PMC6293243</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref9">
        <label>9</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Loncar-Turukalo</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Zdravevski</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Machado da Silva</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Chouvarda</surname>
              <given-names>I</given-names>
            </name>
            <name name-style="western">
              <surname>Trajkovik</surname>
              <given-names>V</given-names>
            </name>
          </person-group>
          <article-title>Literature on wearable technology for connected health: scoping review of research trends, advances, and barriers</article-title>
          <source>J Med Internet Res</source>
          <year>2019</year>
          <month>09</month>
          <day>05</day>
          <volume>21</volume>
          <issue>9</issue>
          <fpage>e14017</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.jmir.org/2019/9/e14017/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/14017</pub-id>
          <pub-id pub-id-type="medline">31489843</pub-id>
          <pub-id pub-id-type="pii">v21i9e14017</pub-id>
          <pub-id pub-id-type="pmcid">PMC6818529</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref10">
        <label>10</label>
        <nlm-citation citation-type="book">
          <source>IEEE RAS/EMBS International Conference on Biomedical Robotics and Biomechatronics</source>
          <year>2012</year>
          <publisher-loc>Piscataway, NJ</publisher-loc>
          <publisher-name>IEEE</publisher-name>
        </nlm-citation>
      </ref>
      <ref id="ref11">
        <label>11</label>
        <nlm-citation citation-type="confproc">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Bargas-Avila</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Hornbæk</surname>
              <given-names>K</given-names>
            </name>
          </person-group>
          <article-title>Old wine in new bottles or novel challenges: a critical analysis of empirical studies of user experience</article-title>
          <source>CHI '11: Proceedings of the SIGCHI Conference on Human Factors in Computing Systems</source>
          <year>2011</year>
          <conf-name>SIGCHI Conference on Human Factors in Computing Systems</conf-name>
          <conf-date>May 7-12, 2011</conf-date>
          <conf-loc>Vancouver, BC, Canada</conf-loc>
          <pub-id pub-id-type="doi">10.1145/1978942.1979336</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref12">
        <label>12</label>
        <nlm-citation citation-type="web">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Becker</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Oxman</surname>
              <given-names>A</given-names>
            </name>
          </person-group>
          <article-title>Chapter 22: Overviews of reviews</article-title>
          <source>Cochrane Handbook for Systematic Reviews of Interventions</source>
          <access-date>2024-11-27</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://handbook-5-1.cochrane.org/chapter_22/22_overviews_of_reviews.htm">https://handbook-5-1.cochrane.org/chapter_22/22_overviews_of_reviews.htm</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref13">
        <label>13</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Bai</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Zhai</surname>
              <given-names>Y</given-names>
            </name>
            <name name-style="western">
              <surname>Liu</surname>
              <given-names>F</given-names>
            </name>
            <name name-style="western">
              <surname>Wang</surname>
              <given-names>Y</given-names>
            </name>
            <name name-style="western">
              <surname>Luo</surname>
              <given-names>S</given-names>
            </name>
          </person-group>
          <article-title>Stretchable graphene thin film enabled yarn sensors with tunable piezoresistivity for human motion monitoring</article-title>
          <source>Sci Rep</source>
          <year>2019</year>
          <month>12</month>
          <day>09</day>
          <volume>9</volume>
          <issue>1</issue>
          <fpage>18644</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://doi.org/10.1038/s41598-019-55262-z"/>
          </comment>
          <pub-id pub-id-type="doi">10.1038/s41598-019-55262-z</pub-id>
          <pub-id pub-id-type="medline">31819146</pub-id>
          <pub-id pub-id-type="pii">10.1038/s41598-019-55262-z</pub-id>
          <pub-id pub-id-type="pmcid">PMC6901454</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref14">
        <label>14</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Formstone</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Huo</surname>
              <given-names>W</given-names>
            </name>
            <name name-style="western">
              <surname>Wilson</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>McGregor</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Bentley</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Vaidyanathan</surname>
              <given-names>R</given-names>
            </name>
          </person-group>
          <article-title>Quantification of motor function post-stroke using novel combination of wearable inertial and mechanomyographic sensors</article-title>
          <source>IEEE Trans Neural Syst Rehabil Eng</source>
          <year>2021</year>
          <volume>29</volume>
          <fpage>1158</fpage>
          <lpage>1167</lpage>
          <pub-id pub-id-type="doi">10.1109/TNSRE.2021.3089613</pub-id>
          <pub-id pub-id-type="medline">34129501</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref15">
        <label>15</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Gu</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Xu</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Peng</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Li</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Chen</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Lu</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Guo</surname>
              <given-names>X</given-names>
            </name>
          </person-group>
          <article-title>Integrated soft ionotronic skin with stretchable and transparent hydrogel-elastomer ionic sensors for hand-motion monitoring</article-title>
          <source>Soft Robot</source>
          <year>2019</year>
          <month>06</month>
          <volume>6</volume>
          <issue>3</issue>
          <fpage>368</fpage>
          <lpage>376</lpage>
          <pub-id pub-id-type="doi">10.1089/soro.2018.0116</pub-id>
          <pub-id pub-id-type="medline">30848994</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref16">
        <label>16</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Lee</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Lee</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Lee</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Ryu</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Kim</surname>
              <given-names>IY</given-names>
            </name>
            <name name-style="western">
              <surname>Kim</surname>
              <given-names>J</given-names>
            </name>
          </person-group>
          <article-title>Clip-on IMU system for assessing age-related changes in hand functions</article-title>
          <source>Sensors (Basel)</source>
          <year>2020</year>
          <month>11</month>
          <day>05</day>
          <volume>20</volume>
          <issue>21</issue>
          <fpage>6313</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.mdpi.com/resolver?pii=s20216313"/>
          </comment>
          <pub-id pub-id-type="doi">10.3390/s20216313</pub-id>
          <pub-id pub-id-type="medline">33167512</pub-id>
          <pub-id pub-id-type="pii">s20216313</pub-id>
          <pub-id pub-id-type="pmcid">PMC7663935</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref17">
        <label>17</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Lee</surname>
              <given-names>SI</given-names>
            </name>
            <name name-style="western">
              <surname>Liu</surname>
              <given-names>X</given-names>
            </name>
            <name name-style="western">
              <surname>Rajan</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Ramasarma</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Choe</surname>
              <given-names>EK</given-names>
            </name>
            <name name-style="western">
              <surname>Bonato</surname>
              <given-names>P</given-names>
            </name>
          </person-group>
          <article-title>A novel upper-limb function measure derived from finger-worn sensor data collected in a free-living setting</article-title>
          <source>PLoS One</source>
          <year>2019</year>
          <volume>14</volume>
          <issue>3</issue>
          <fpage>e0212484</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://dx.plos.org/10.1371/journal.pone.0212484"/>
          </comment>
          <pub-id pub-id-type="doi">10.1371/journal.pone.0212484</pub-id>
          <pub-id pub-id-type="medline">30893308</pub-id>
          <pub-id pub-id-type="pii">PONE-D-18-28807</pub-id>
          <pub-id pub-id-type="pmcid">PMC6426183</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref18">
        <label>18</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Li</surname>
              <given-names>Y</given-names>
            </name>
            <name name-style="western">
              <surname>Zhang</surname>
              <given-names>X</given-names>
            </name>
            <name name-style="western">
              <surname>Gong</surname>
              <given-names>Y</given-names>
            </name>
            <name name-style="western">
              <surname>Cheng</surname>
              <given-names>Y</given-names>
            </name>
            <name name-style="western">
              <surname>Gao</surname>
              <given-names>X</given-names>
            </name>
            <name name-style="western">
              <surname>Chen</surname>
              <given-names>X</given-names>
            </name>
          </person-group>
          <article-title>Motor function evaluation of hemiplegic upper-extremities using data fusion from wearable inertial and surface EMG sensors</article-title>
          <source>Sensors (Basel)</source>
          <year>2017</year>
          <month>03</month>
          <day>13</day>
          <volume>17</volume>
          <issue>3</issue>
          <fpage>582</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.mdpi.com/resolver?pii=s17030582"/>
          </comment>
          <pub-id pub-id-type="doi">10.3390/s17030582</pub-id>
          <pub-id pub-id-type="medline">28335394</pub-id>
          <pub-id pub-id-type="pii">s17030582</pub-id>
          <pub-id pub-id-type="pmcid">PMC5375868</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref19">
        <label>19</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Little</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>K Pappachan</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Yang</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Noronha</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Campolo</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Accoto</surname>
              <given-names>D</given-names>
            </name>
          </person-group>
          <article-title>Elbow motion trajectory prediction using a multi-modal wearable system: a comparative analysis of machine learning techniques</article-title>
          <source>Sensors (Basel)</source>
          <year>2021</year>
          <month>01</month>
          <day>12</day>
          <volume>21</volume>
          <issue>2</issue>
          <fpage>498</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.mdpi.com/resolver?pii=s21020498"/>
          </comment>
          <pub-id pub-id-type="doi">10.3390/s21020498</pub-id>
          <pub-id pub-id-type="medline">33445601</pub-id>
          <pub-id pub-id-type="pii">s21020498</pub-id>
          <pub-id pub-id-type="pmcid">PMC7827251</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref20">
        <label>20</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Repnik</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Puh</surname>
              <given-names>U</given-names>
            </name>
            <name name-style="western">
              <surname>Goljar</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Munih</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Mihelj</surname>
              <given-names>M</given-names>
            </name>
          </person-group>
          <article-title>Using inertial measurement units and electromyography to quantify movement during action research arm test execution</article-title>
          <source>Sensors (Basel)</source>
          <year>2018</year>
          <month>08</month>
          <day>22</day>
          <volume>18</volume>
          <issue>9</issue>
          <fpage>2767</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.mdpi.com/resolver?pii=s18092767"/>
          </comment>
          <pub-id pub-id-type="doi">10.3390/s18092767</pub-id>
          <pub-id pub-id-type="medline">30135413</pub-id>
          <pub-id pub-id-type="pii">s18092767</pub-id>
          <pub-id pub-id-type="pmcid">PMC6164634</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref21">
        <label>21</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Schwarz</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Bhagubai</surname>
              <given-names>MMC</given-names>
            </name>
            <name name-style="western">
              <surname>Wolterink</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Held</surname>
              <given-names>JPO</given-names>
            </name>
            <name name-style="western">
              <surname>Luft</surname>
              <given-names>AR</given-names>
            </name>
            <name name-style="western">
              <surname>Veltink</surname>
              <given-names>PH</given-names>
            </name>
          </person-group>
          <article-title>Assessment of upper limb movement impairments after stroke using wearable inertial sensing</article-title>
          <source>Sensors (Basel)</source>
          <year>2020</year>
          <month>08</month>
          <day>24</day>
          <volume>20</volume>
          <issue>17</issue>
          <fpage>2767</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.mdpi.com/resolver?pii=s20174770"/>
          </comment>
          <pub-id pub-id-type="doi">10.3390/s20174770</pub-id>
          <pub-id pub-id-type="medline">32846958</pub-id>
          <pub-id pub-id-type="pii">s20174770</pub-id>
          <pub-id pub-id-type="pmcid">PMC7506737</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref22">
        <label>22</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Schwerz de Lucena</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Rowe</surname>
              <given-names>JB</given-names>
            </name>
            <name name-style="western">
              <surname>Okita</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Chan</surname>
              <given-names>V</given-names>
            </name>
            <name name-style="western">
              <surname>Cramer</surname>
              <given-names>SC</given-names>
            </name>
            <name name-style="western">
              <surname>Reinkensmeyer</surname>
              <given-names>DJ</given-names>
            </name>
          </person-group>
          <article-title>Providing real-time wearable feedback to increase hand use after stroke: a randomized, controlled trial</article-title>
          <source>Sensors (Basel)</source>
          <year>2022</year>
          <month>09</month>
          <day>14</day>
          <volume>22</volume>
          <issue>18</issue>
          <fpage>6938</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.mdpi.com/resolver?pii=s22186938"/>
          </comment>
          <pub-id pub-id-type="doi">10.3390/s22186938</pub-id>
          <pub-id pub-id-type="medline">36146287</pub-id>
          <pub-id pub-id-type="pii">s22186938</pub-id>
          <pub-id pub-id-type="pmcid">PMC9505054</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref23">
        <label>23</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Tolvanen</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Hannu</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Jantunen</surname>
              <given-names>H</given-names>
            </name>
          </person-group>
          <article-title>Stretchable and washable strain sensor based on cracking structure for human motion monitoring</article-title>
          <source>Sci Rep</source>
          <year>2018</year>
          <month>09</month>
          <day>05</day>
          <volume>8</volume>
          <issue>1</issue>
          <fpage>13241</fpage>
          <pub-id pub-id-type="doi">10.1038/s41598-018-31628-7</pub-id>
          <pub-id pub-id-type="medline">30185926</pub-id>
          <pub-id pub-id-type="pii">10.1038/s41598-018-31628-7</pub-id>
          <pub-id pub-id-type="pmcid">PMC6125599</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref24">
        <label>24</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Wang</surname>
              <given-names>Q</given-names>
            </name>
            <name name-style="western">
              <surname>De Baets</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Timmermans</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Chen</surname>
              <given-names>W</given-names>
            </name>
            <name name-style="western">
              <surname>Giacolini</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Matheve</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Markopoulos</surname>
              <given-names>P</given-names>
            </name>
          </person-group>
          <article-title>Motor control training for the shoulder with smart garments</article-title>
          <source>Sensors (Basel)</source>
          <year>2017</year>
          <month>07</month>
          <day>22</day>
          <volume>17</volume>
          <issue>7</issue>
          <fpage>1687</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.mdpi.com/resolver?pii=s17071687"/>
          </comment>
          <pub-id pub-id-type="doi">10.3390/s17071687</pub-id>
          <pub-id pub-id-type="medline">28737670</pub-id>
          <pub-id pub-id-type="pii">s17071687</pub-id>
          <pub-id pub-id-type="pmcid">PMC5539564</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref25">
        <label>25</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Zhang</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Liu</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Zhang</surname>
              <given-names>Y</given-names>
            </name>
            <name name-style="western">
              <surname>Zhu</surname>
              <given-names>R</given-names>
            </name>
          </person-group>
          <article-title>A method to extract motion velocities of limb and trunk in human locomotion</article-title>
          <source>IEEE Access</source>
          <year>2020</year>
          <volume>8</volume>
          <fpage>120553</fpage>
          <lpage>120561</lpage>
          <pub-id pub-id-type="doi">10.1109/access.2020.3006336</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref26">
        <label>26</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Zhang</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Chen</surname>
              <given-names>Y</given-names>
            </name>
            <name name-style="western">
              <surname>Li</surname>
              <given-names>Y</given-names>
            </name>
            <name name-style="western">
              <surname>Zhang</surname>
              <given-names>Y</given-names>
            </name>
            <name name-style="western">
              <surname>Zhang</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Huang</surname>
              <given-names>L</given-names>
            </name>
          </person-group>
          <article-title>Correction: Zhang, P., et al. A flexible strain sensor based on the porous structure of a carbon black/carbon nanotube conducting network for human motion detection. Sensors 2020, 20, 1154</article-title>
          <source>Sensors (Basel)</source>
          <year>2020</year>
          <month>05</month>
          <day>20</day>
          <volume>20</volume>
          <issue>10</issue>
          <fpage>2901</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.mdpi.com/resolver?pii=s20102901"/>
          </comment>
          <pub-id pub-id-type="doi">10.3390/s20102901</pub-id>
          <pub-id pub-id-type="medline">32443818</pub-id>
          <pub-id pub-id-type="pii">s20102901</pub-id>
          <pub-id pub-id-type="pmcid">PMC7284713</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref27">
        <label>27</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Yu</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Xiong</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Guo</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Wang</surname>
              <given-names>J</given-names>
            </name>
          </person-group>
          <article-title>A compressed sensing-based wearable sensor network for quantitative assessment of stroke patients</article-title>
          <source>Sensors (Basel)</source>
          <year>2016</year>
          <month>02</month>
          <day>05</day>
          <volume>16</volume>
          <issue>2</issue>
          <fpage>202</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.mdpi.com/resolver?pii=s16020202"/>
          </comment>
          <pub-id pub-id-type="doi">10.3390/s16020202</pub-id>
          <pub-id pub-id-type="medline">26861337</pub-id>
          <pub-id pub-id-type="pii">s16020202</pub-id>
          <pub-id pub-id-type="pmcid">PMC4801578</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref28">
        <label>28</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Wang</surname>
              <given-names>Q</given-names>
            </name>
            <name name-style="western">
              <surname>Timmermans</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Chen</surname>
              <given-names>W</given-names>
            </name>
            <name name-style="western">
              <surname>Jia</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Ding</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Xiong</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Rong</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Markopoulos</surname>
              <given-names>P</given-names>
            </name>
          </person-group>
          <article-title>Stroke patients’ acceptance of a smart garment for supporting upper extremity rehabilitation</article-title>
          <source>IEEE J. Transl. Eng. Health Med</source>
          <year>2018</year>
          <volume>6</volume>
          <fpage>1</fpage>
          <lpage>9</lpage>
          <pub-id pub-id-type="doi">10.1109/jtehm.2018.2853549</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref29">
        <label>29</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Friedman</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Rowe</surname>
              <given-names>JB</given-names>
            </name>
            <name name-style="western">
              <surname>Reinkensmeyer</surname>
              <given-names>DJ</given-names>
            </name>
            <name name-style="western">
              <surname>Bachman</surname>
              <given-names>M</given-names>
            </name>
          </person-group>
          <article-title>The manumeter: a wearable device for monitoring daily use of the wrist and fingers</article-title>
          <source>IEEE J Biomed Health Inform</source>
          <year>2014</year>
          <month>11</month>
          <volume>18</volume>
          <issue>6</issue>
          <fpage>1804</fpage>
          <lpage>12</lpage>
          <pub-id pub-id-type="doi">10.1109/JBHI.2014.2329841</pub-id>
          <pub-id pub-id-type="medline">25014974</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref30">
        <label>30</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Kim</surname>
              <given-names>DH</given-names>
            </name>
            <name name-style="western">
              <surname>Lee</surname>
              <given-names>SW</given-names>
            </name>
            <name name-style="western">
              <surname>Park</surname>
              <given-names>H</given-names>
            </name>
          </person-group>
          <article-title>Improving kinematic accuracy of soft wearable data gloves by optimizing sensor locations</article-title>
          <source>Sensors (Basel)</source>
          <year>2016</year>
          <month>05</month>
          <day>26</day>
          <volume>16</volume>
          <issue>6</issue>
          <fpage>766</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.mdpi.com/resolver?pii=s16060766"/>
          </comment>
          <pub-id pub-id-type="doi">10.3390/s16060766</pub-id>
          <pub-id pub-id-type="medline">27240364</pub-id>
          <pub-id pub-id-type="pii">s16060766</pub-id>
          <pub-id pub-id-type="pmcid">PMC4934192</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref31">
        <label>31</label>
        <nlm-citation citation-type="confproc">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Kim</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Yang</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Gerla</surname>
              <given-names>M</given-names>
            </name>
          </person-group>
          <article-title>StrokeTrack: wireless inertial motion tracking of human arms for stroke telerehabilitation</article-title>
          <source>mHealthSys '11: Proceedings of the First ACM Workshop on Mobile Systems, Applications, and Services for Healthcare</source>
          <year>2011</year>
          <conf-name>9th ACM Conference on Embedded Network Sensor Systems</conf-name>
          <conf-date>November 1, 2011</conf-date>
          <conf-loc>Seattle, Washington</conf-loc>
          <pub-id pub-id-type="doi">10.1145/2064942.2064948</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref32">
        <label>32</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Kortier</surname>
              <given-names>HG</given-names>
            </name>
            <name name-style="western">
              <surname>Sluiter</surname>
              <given-names>VI</given-names>
            </name>
            <name name-style="western">
              <surname>Roetenberg</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Veltink</surname>
              <given-names>PH</given-names>
            </name>
          </person-group>
          <article-title>Assessment of hand kinematics using inertial and magnetic sensors</article-title>
          <source>J Neuroeng Rehabil</source>
          <year>2014</year>
          <month>04</month>
          <day>21</day>
          <volume>11</volume>
          <fpage>70</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://jneuroengrehab.biomedcentral.com/articles/10.1186/1743-0003-11-70"/>
          </comment>
          <pub-id pub-id-type="doi">10.1186/1743-0003-11-70</pub-id>
          <pub-id pub-id-type="medline">24746123</pub-id>
          <pub-id pub-id-type="pii">1743-0003-11-70</pub-id>
          <pub-id pub-id-type="pmcid">PMC4019393</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref33">
        <label>33</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Liu</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Shao</surname>
              <given-names>Q</given-names>
            </name>
            <name name-style="western">
              <surname>Wang</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Ru</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Balkcom</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Zhou</surname>
              <given-names>X</given-names>
            </name>
          </person-group>
          <article-title>Reconstructing human joint motion with computational fabrics</article-title>
          <source>Proc ACM Interact Mob Wearable Ubiquitous Technol</source>
          <year>2019</year>
          <month>03</month>
          <day>29</day>
          <volume>3</volume>
          <issue>1</issue>
          <fpage>1</fpage>
          <lpage>26</lpage>
          <pub-id pub-id-type="doi">10.1145/3314406</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref34">
        <label>34</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Mohammadzadeh</surname>
              <given-names>FF</given-names>
            </name>
            <name name-style="western">
              <surname>Liu</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Bond</surname>
              <given-names>KA</given-names>
            </name>
            <name name-style="western">
              <surname>Nam</surname>
              <given-names>CS</given-names>
            </name>
          </person-group>
          <article-title>Feasibility of a wearable, sensor-based motion tracking system</article-title>
          <source>Procedia Manufacturing</source>
          <year>2015</year>
          <volume>3</volume>
          <fpage>192</fpage>
          <lpage>199</lpage>
          <pub-id pub-id-type="doi">10.1016/j.promfg.2015.07.128</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref35">
        <label>35</label>
        <nlm-citation citation-type="confproc">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Ploderer</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Fong</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Withana</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Klaic</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Nair</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Crocher</surname>
              <given-names>V</given-names>
            </name>
            <name name-style="western">
              <surname>Vetere</surname>
              <given-names>F</given-names>
            </name>
            <name name-style="western">
              <surname>Nanayakkara</surname>
              <given-names>S</given-names>
            </name>
          </person-group>
          <article-title>ArmSleeve: A Patient Monitoring System to Support Occupational Therapists in Stroke Rehabilitation</article-title>
          <source>DIS '16: Proceedings of the 2016 ACM Conference on Designing Interactive Systems</source>
          <year>2016</year>
          <conf-name>DIS '16: Designing Interactive Systems Conference</conf-name>
          <conf-date>June 4-8, 2016</conf-date>
          <conf-loc>Brisbane, QLD, Australia</conf-loc>
          <pub-id pub-id-type="doi">10.1145/2901790.2901799</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref36">
        <label>36</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Pregnolato</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Rimini</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Baldan</surname>
              <given-names>F</given-names>
            </name>
            <name name-style="western">
              <surname>Maistrello</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Salvalaggio</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Celadon</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Ariano</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Pirri</surname>
              <given-names>CF</given-names>
            </name>
            <name name-style="western">
              <surname>Turolla</surname>
              <given-names>A</given-names>
            </name>
          </person-group>
          <article-title>Clinical features to predict the use of a sEMG wearable device (REMO) for hand motor training of stroke patients: a cross-sectional cohort study</article-title>
          <source>Int J Environ Res Public Health</source>
          <year>2023</year>
          <month>03</month>
          <day>14</day>
          <volume>20</volume>
          <issue>6</issue>
          <fpage>5082</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.mdpi.com/resolver?pii=ijerph20065082"/>
          </comment>
          <pub-id pub-id-type="doi">10.3390/ijerph20065082</pub-id>
          <pub-id pub-id-type="medline">36981992</pub-id>
          <pub-id pub-id-type="pii">ijerph20065082</pub-id>
          <pub-id pub-id-type="pmcid">PMC10049214</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref37">
        <label>37</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Salchow-Hömmen</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Callies</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Laidig</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Valtin</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Schauer</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Seel</surname>
              <given-names>T</given-names>
            </name>
          </person-group>
          <article-title>A tangible solution for hand motion tracking in clinical applications</article-title>
          <source>Sensors (Basel)</source>
          <year>2019</year>
          <month>01</month>
          <day>08</day>
          <volume>19</volume>
          <issue>1</issue>
          <fpage>208</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.mdpi.com/resolver?pii=s19010208"/>
          </comment>
          <pub-id pub-id-type="doi">10.3390/s19010208</pub-id>
          <pub-id pub-id-type="medline">30626130</pub-id>
          <pub-id pub-id-type="pii">s19010208</pub-id>
          <pub-id pub-id-type="pmcid">PMC6339214</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref38">
        <label>38</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Semjonova</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Vetra</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Cauce</surname>
              <given-names>V</given-names>
            </name>
            <name name-style="western">
              <surname>Oks</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Katashev</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Eizentals</surname>
              <given-names>P</given-names>
            </name>
          </person-group>
          <article-title>Improving the recovery of patients with subacromial pain syndrome with the DAid Smart Textile Shirt</article-title>
          <source>Sensors (Basel)</source>
          <year>2020</year>
          <month>09</month>
          <day>15</day>
          <volume>20</volume>
          <issue>18</issue>
          <fpage>5277</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.mdpi.com/resolver?pii=s20185277"/>
          </comment>
          <pub-id pub-id-type="doi">10.3390/s20185277</pub-id>
          <pub-id pub-id-type="medline">32942730</pub-id>
          <pub-id pub-id-type="pii">s20185277</pub-id>
          <pub-id pub-id-type="pmcid">PMC7570826</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref39">
        <label>39</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Ding</surname>
              <given-names>ZQ</given-names>
            </name>
            <name name-style="western">
              <surname>Luo</surname>
              <given-names>ZQ</given-names>
            </name>
            <name name-style="western">
              <surname>Causo</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Chen</surname>
              <given-names>IM</given-names>
            </name>
            <name name-style="western">
              <surname>Yue</surname>
              <given-names>KX</given-names>
            </name>
            <name name-style="western">
              <surname>Yeo</surname>
              <given-names>SH</given-names>
            </name>
            <name name-style="western">
              <surname>Ling</surname>
              <given-names>KV</given-names>
            </name>
          </person-group>
          <article-title>Inertia sensor-based guidance system for upperlimb posture correction</article-title>
          <source>Med Eng Phys</source>
          <year>2013</year>
          <month>02</month>
          <volume>35</volume>
          <issue>2</issue>
          <fpage>269</fpage>
          <lpage>76</lpage>
          <pub-id pub-id-type="doi">10.1016/j.medengphy.2011.09.002</pub-id>
          <pub-id pub-id-type="medline">21978912</pub-id>
          <pub-id pub-id-type="pii">S1350-4533(11)00227-X</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref40">
        <label>40</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Simpson</surname>
              <given-names>LA</given-names>
            </name>
            <name name-style="western">
              <surname>Menon</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Hodgson</surname>
              <given-names>AJ</given-names>
            </name>
            <name name-style="western">
              <surname>Ben Mortenson</surname>
              <given-names>W</given-names>
            </name>
            <name name-style="western">
              <surname>Eng</surname>
              <given-names>JJ</given-names>
            </name>
          </person-group>
          <article-title>Clinicians' perceptions of a potential wearable device for capturing upper limb activity post-stroke: a qualitative focus group study</article-title>
          <source>J Neuroeng Rehabil</source>
          <year>2021</year>
          <month>09</month>
          <day>08</day>
          <volume>18</volume>
          <issue>1</issue>
          <fpage>135</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://jneuroengrehab.biomedcentral.com/articles/10.1186/s12984-021-00927-y"/>
          </comment>
          <pub-id pub-id-type="doi">10.1186/s12984-021-00927-y</pub-id>
          <pub-id pub-id-type="medline">34496894</pub-id>
          <pub-id pub-id-type="pii">10.1186/s12984-021-00927-y</pub-id>
          <pub-id pub-id-type="pmcid">PMC8425094</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref41">
        <label>41</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Toh</surname>
              <given-names>SFM</given-names>
            </name>
            <name name-style="western">
              <surname>Gonzalez</surname>
              <given-names>PC</given-names>
            </name>
            <name name-style="western">
              <surname>Fong</surname>
              <given-names>KNK</given-names>
            </name>
          </person-group>
          <article-title>Usability of a wearable device for home-based upper limb telerehabilitation in persons with stroke: A mixed-methods study</article-title>
          <source>Digit Health</source>
          <year>2023</year>
          <month>02</month>
          <day>07</day>
          <volume>9</volume>
          <fpage>20552076231153737</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://journals.sagepub.com/doi/10.1177/20552076231153737?url_ver=Z39.88-2003&#38;rfr_id=ori:rid:crossref.org&#38;rfr_dat=cr_pub  0pubmed"/>
          </comment>
          <pub-id pub-id-type="doi">10.1177/20552076231153737</pub-id>
          <pub-id pub-id-type="medline">36776407</pub-id>
          <pub-id pub-id-type="pii">10.1177_20552076231153737</pub-id>
          <pub-id pub-id-type="pmcid">PMC9909064</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref42">
        <label>42</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Khan</surname>
              <given-names>Y</given-names>
            </name>
            <name name-style="western">
              <surname>Ostfeld</surname>
              <given-names>AE</given-names>
            </name>
            <name name-style="western">
              <surname>Lochner</surname>
              <given-names>CM</given-names>
            </name>
            <name name-style="western">
              <surname>Pierre</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Arias</surname>
              <given-names>AC</given-names>
            </name>
          </person-group>
          <article-title>Monitoring of vital signs with flexible and wearable medical devices</article-title>
          <source>Adv Mater</source>
          <year>2016</year>
          <month>06</month>
          <volume>28</volume>
          <issue>22</issue>
          <fpage>4373</fpage>
          <lpage>95</lpage>
          <pub-id pub-id-type="doi">10.1002/adma.201504366</pub-id>
          <pub-id pub-id-type="medline">26867696</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref43">
        <label>43</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Beniwal</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Kalra</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Beniwal</surname>
              <given-names>NS</given-names>
            </name>
            <name name-style="western">
              <surname>Mazumdar</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Singhal</surname>
              <given-names>AK</given-names>
            </name>
            <name name-style="western">
              <surname>Singh</surname>
              <given-names>SK</given-names>
            </name>
          </person-group>
          <article-title>Walk‐to‐charge technology: exploring efficient energy harvesting solutions for smart electronics</article-title>
          <source>Journal of Sensors</source>
          <year>2023</year>
          <month>10</month>
          <day>10</day>
          <volume>2023</volume>
          <issue>1</issue>
          <fpage>614658</fpage>
          <pub-id pub-id-type="doi">10.1155/2023/6614658</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref44">
        <label>44</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Vidhya</surname>
              <given-names>CM</given-names>
            </name>
            <name name-style="western">
              <surname>Maithani</surname>
              <given-names>Y</given-names>
            </name>
            <name name-style="western">
              <surname>Singh</surname>
              <given-names>JP</given-names>
            </name>
          </person-group>
          <article-title>Recent advances and challenges in textile electrodes for wearable biopotential signal monitoring: a comprehensive review</article-title>
          <source>Biosensors (Basel)</source>
          <year>2023</year>
          <month>06</month>
          <day>26</day>
          <volume>13</volume>
          <issue>7</issue>
          <fpage>679</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.mdpi.com/resolver?pii=bios13070679"/>
          </comment>
          <pub-id pub-id-type="doi">10.3390/bios13070679</pub-id>
          <pub-id pub-id-type="medline">37504078</pub-id>
          <pub-id pub-id-type="pii">bios13070679</pub-id>
          <pub-id pub-id-type="pmcid">PMC10377545</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref45">
        <label>45</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Meena</surname>
              <given-names>JS</given-names>
            </name>
            <name name-style="western">
              <surname>Choi</surname>
              <given-names>SB</given-names>
            </name>
            <name name-style="western">
              <surname>Jung</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Kim</surname>
              <given-names>J</given-names>
            </name>
          </person-group>
          <article-title>Electronic textiles: New age of wearable technology for healthcare and fitness solutions</article-title>
          <source>Mater Today Bio</source>
          <year>2023</year>
          <month>04</month>
          <volume>19</volume>
          <fpage>100565</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://linkinghub.elsevier.com/retrieve/pii/S2590-0064(23)00025-X"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/j.mtbio.2023.100565</pub-id>
          <pub-id pub-id-type="medline">36816602</pub-id>
          <pub-id pub-id-type="pii">S2590-0064(23)00025-X</pub-id>
          <pub-id pub-id-type="pmcid">PMC9932217</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref46">
        <label>46</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Candes</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Wakin</surname>
              <given-names>M</given-names>
            </name>
          </person-group>
          <article-title>An introduction to compressive sampling</article-title>
          <source>IEEE Signal Process Mag</source>
          <year>2008</year>
          <month>03</month>
          <volume>25</volume>
          <issue>2</issue>
          <fpage>21</fpage>
          <lpage>30</lpage>
          <pub-id pub-id-type="doi">10.1109/msp.2007.914731</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref47">
        <label>47</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Pagan</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Fallahzadeh</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Pedram</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Risco-Martin</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Moya</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Ayala</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Ghasemzadeh</surname>
              <given-names>H</given-names>
            </name>
          </person-group>
          <article-title>Toward ultra-low-power remote health monitoring: an optimal and adaptive compressed sensing framework for activity recognition</article-title>
          <source>IEEE Trans on Mobile Comput</source>
          <year>2019</year>
          <month>3</month>
          <day>1</day>
          <volume>18</volume>
          <issue>3</issue>
          <fpage>658</fpage>
          <lpage>673</lpage>
          <pub-id pub-id-type="doi">10.1109/tmc.2018.2843373</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref48">
        <label>48</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Kerdjidj</surname>
              <given-names>O</given-names>
            </name>
            <name name-style="western">
              <surname>Ramzan</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Ghanem</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Amira</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Chouireb</surname>
              <given-names>F</given-names>
            </name>
          </person-group>
          <article-title>Fall detection and human activity classification using wearable sensors and compressed sensing</article-title>
          <source>J Ambient Intell Human Comput</source>
          <year>2019</year>
          <month>1</month>
          <day>31</day>
          <volume>11</volume>
          <issue>1</issue>
          <fpage>349</fpage>
          <lpage>361</lpage>
          <pub-id pub-id-type="doi">10.1007/s12652-019-01214-4</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref49">
        <label>49</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Culman</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Aminikhanghahi</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>J Cook</surname>
              <given-names>D</given-names>
            </name>
          </person-group>
          <article-title>Easing power consumption of wearable activity monitoring with change point detection</article-title>
          <source>Sensors (Basel)</source>
          <year>2020</year>
          <month>01</month>
          <day>06</day>
          <volume>20</volume>
          <issue>1</issue>
          <fpage>310</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.mdpi.com/resolver?pii=s20010310"/>
          </comment>
          <pub-id pub-id-type="doi">10.3390/s20010310</pub-id>
          <pub-id pub-id-type="medline">31935907</pub-id>
          <pub-id pub-id-type="pii">s20010310</pub-id>
          <pub-id pub-id-type="pmcid">PMC6982794</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref50">
        <label>50</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Bermejo</surname>
              <given-names>U</given-names>
            </name>
            <name name-style="western">
              <surname>Almeida</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Bilbao-Jayo</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Azkune</surname>
              <given-names>G</given-names>
            </name>
          </person-group>
          <article-title>Embedding-based real-time change point detection with application to activity segmentation in smart home time series data</article-title>
          <source>Expert Systems with Applications</source>
          <year>2021</year>
          <month>12</month>
          <volume>185</volume>
          <fpage>115641</fpage>
          <pub-id pub-id-type="doi">10.1016/j.eswa.2021.115641</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref51">
        <label>51</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Rong</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Zheng</surname>
              <given-names>Y</given-names>
            </name>
            <name name-style="western">
              <surname>Sawan</surname>
              <given-names>M</given-names>
            </name>
          </person-group>
          <article-title>Energy solutions for wearable sensors: a review</article-title>
          <source>Sensors (Basel)</source>
          <year>2021</year>
          <month>05</month>
          <day>31</day>
          <volume>21</volume>
          <issue>11</issue>
          <fpage>3806</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.mdpi.com/resolver?pii=s21113806"/>
          </comment>
          <pub-id pub-id-type="doi">10.3390/s21113806</pub-id>
          <pub-id pub-id-type="medline">34072770</pub-id>
          <pub-id pub-id-type="pii">s21113806</pub-id>
          <pub-id pub-id-type="pmcid">PMC8197793</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref52">
        <label>52</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Rudenko</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Palmieri</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Herman</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Kitani</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Gavrila</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Arras</surname>
              <given-names>K</given-names>
            </name>
          </person-group>
          <article-title>Human motion trajectory prediction: a survey</article-title>
          <source>The International Journal of Robotics Research</source>
          <year>2020</year>
          <month>06</month>
          <day>07</day>
          <volume>39</volume>
          <issue>8</issue>
          <fpage>895</fpage>
          <lpage>935</lpage>
          <pub-id pub-id-type="doi">10.1177/0278364920917446</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref53">
        <label>53</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Frangoudes</surname>
              <given-names>F</given-names>
            </name>
            <name name-style="western">
              <surname>Matsangidou</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Schiza</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Neokleous</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Pattichis</surname>
              <given-names>C</given-names>
            </name>
          </person-group>
          <article-title>Assessing human motion during exercise using machine learning: a literature review</article-title>
          <source>IEEE Access</source>
          <year>2022</year>
          <volume>10</volume>
          <fpage>86874</fpage>
          <lpage>86903</lpage>
          <pub-id pub-id-type="doi">10.1109/access.2022.3198935</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref54">
        <label>54</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Diab</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Rodriguez-Villegas</surname>
              <given-names>E</given-names>
            </name>
          </person-group>
          <article-title>Embedded machine learning using microcontrollers in wearable and ambulatory systems for health and care applications: a review</article-title>
          <source>IEEE Access</source>
          <year>2022</year>
          <volume>10</volume>
          <fpage>98450</fpage>
          <lpage>98474</lpage>
          <pub-id pub-id-type="doi">10.1109/access.2022.3206782</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref55">
        <label>55</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Huang</surname>
              <given-names>Y</given-names>
            </name>
            <name name-style="western">
              <surname>Yao</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Li</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Li</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Jia</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Liu</surname>
              <given-names>Y</given-names>
            </name>
            <name name-style="western">
              <surname>Yiu</surname>
              <given-names>CK</given-names>
            </name>
            <name name-style="western">
              <surname>Park</surname>
              <given-names>W</given-names>
            </name>
            <name name-style="western">
              <surname>Yu</surname>
              <given-names>X</given-names>
            </name>
          </person-group>
          <article-title>Recent advances in multi-mode haptic feedback technologies towards wearable interfaces</article-title>
          <source>Materials Today Physics</source>
          <year>2022</year>
          <month>01</month>
          <volume>22</volume>
          <fpage>100602</fpage>
          <pub-id pub-id-type="doi">10.1016/j.mtphys.2021.100602</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref56">
        <label>56</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Yin</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Hinchet</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Shea</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Majidi</surname>
              <given-names>C</given-names>
            </name>
          </person-group>
          <article-title>Wearable soft technologies for haptic sensing and feedback</article-title>
          <source>Adv Funct Materials</source>
          <year>2020</year>
          <month>12</month>
          <day>31</day>
          <volume>31</volume>
          <issue>39</issue>
          <fpage>7428</fpage>
          <pub-id pub-id-type="doi">10.1002/adfm.202007428</pub-id>
        </nlm-citation>
      </ref>
    </ref-list>
  </back>
</article>
