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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JMIR</journal-id>
      <journal-id journal-id-type="nlm-ta">J Med Internet Res</journal-id>
      <journal-title>Journal of Medical Internet Research</journal-title>
      <issn pub-type="epub">1438-8871</issn>
      <publisher>
        <publisher-name>JMIR Publications</publisher-name>
        <publisher-loc>Toronto, Canada</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">v26i1e48493</article-id>
      <article-id pub-id-type="pmid">38526554</article-id>
      <article-id pub-id-type="doi">10.2196/48493</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Viewpoint</subject>
        </subj-group>
        <subj-group subj-group-type="article-type">
          <subject>Viewpoint</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Mitigating Health-Related Uncertainties During Pregnancy: The Role of Smart Health Monitoring Technologies</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="editor">
          <name>
            <surname>Mavragani</surname>
            <given-names>Amaryllis</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Pimentel</surname>
            <given-names>Maria da Graca</given-names>
          </name>
        </contrib>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Baker</surname>
            <given-names>Elizabeth</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib id="contrib1" contrib-type="author" corresp="yes">
          <name name-style="western">
            <surname>Tretter</surname>
            <given-names>Max</given-names>
          </name>
          <degrees>Mag Theol</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <address>
            <institution>Chair of Systematic Theology (Ethics)</institution>
            <institution>Seminar for Systematic Theology</institution>
            <institution>Friedrich-Alexander-Universität Erlangen-Nürnberg</institution>
            <addr-line>Kochstr 6</addr-line>
            <addr-line>Erlangen, 91054</addr-line>
            <country>Germany</country>
            <phone>49 9131 85 26078</phone>
            <email>max.tretter@fau.de</email>
          </address>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0001-8067-247X</ext-link>
        </contrib>
      </contrib-group>
      <aff id="aff1">
        <label>1</label>
        <institution>Chair of Systematic Theology (Ethics)</institution>
        <institution>Seminar for Systematic Theology</institution>
        <institution>Friedrich-Alexander-Universität Erlangen-Nürnberg</institution>
        <addr-line>Erlangen</addr-line>
        <country>Germany</country>
      </aff>
      <author-notes>
        <corresp>Corresponding Author: Max Tretter <email>max.tretter@fau.de</email></corresp>
      </author-notes>
      <pub-date pub-type="collection">
        <year>2024</year>
      </pub-date>
      <pub-date pub-type="epub">
        <day>25</day>
        <month>3</month>
        <year>2024</year>
      </pub-date>
      <volume>26</volume>
      <elocation-id>e48493</elocation-id>
      <history>
        <date date-type="received">
          <day>25</day>
          <month>4</month>
          <year>2023</year>
        </date>
        <date date-type="rev-request">
          <day>11</day>
          <month>1</month>
          <year>2024</year>
        </date>
        <date date-type="rev-recd">
          <day>26</day>
          <month>1</month>
          <year>2024</year>
        </date>
        <date date-type="accepted">
          <day>23</day>
          <month>2</month>
          <year>2024</year>
        </date>
      </history>
      <copyright-statement>©Max Tretter. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 25.03.2024.</copyright-statement>
      <copyright-year>2024</copyright-year>
      <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
        <p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Journal of Medical Internet Research, is properly cited. The complete bibliographic information, a link to the original publication on https://www.jmir.org/, as well as this copyright and license information must be included.</p>
      </license>
      <self-uri xlink:href="https://www.jmir.org/2024/1/e48493" xlink:type="simple"/>
      <abstract>
        <p>Pregnancy is a time filled with uncertainties, which can be challenging and lead to fear or anxiety for expectant parents. Health monitoring technologies that allow monitoring of the vital signs of both the mother and fetus offer a way to address health-related uncertainties. But are smart health monitoring technologies (SHMTs) actually an effective means to reduce uncertainties during pregnancy, or do they have the opposite effect? Using conceptual reasoning and phenomenological approaches grounded in existing literature, this Viewpoint explores the effects of SHMTs on health-related uncertainties during pregnancy. The argument posits that while SHMTs can alleviate some health-related uncertainties, they may also create new ones. This is particularly the case when the abundance of vital data overwhelms pregnant persons, leads to false-positive diagnoses, or raises concerns about the accuracy and analysis of data. Consequently, it is concluded that the use of SHMTs is not a cure-all for overcoming health-related uncertainties during pregnancy. Since the use of such monitoring technologies can introduce new uncertainties, it is important to carefully consider where and for what purpose they are used, use them sparingly, and promote a pragmatic approach to uncertainties.Using conceptual reasoning and phenomenological approaches grounded in existing literature, the effects of SHMTs on health-related uncertainties during pregnancy are explored. The argument posits that while SHMTs can alleviate some health-related uncertainties, they may also create new ones. This is particularly the case when the abundance of vital data overwhelms pregnant persons, leads to false-positive diagnoses, or raises concerns about the accuracy and analysis of data.
Consequently, it is concluded that the use of SHMTs is not a cure-all for overcoming health-related uncertainties during pregnancy. Since the use of such monitoring technologies can introduce new uncertainties, it is important to carefully consider where and for what purpose they are used, use them sparingly, and promote a pragmatic approach to uncertainties.</p>
      </abstract>
      <kwd-group>
        <kwd>stress</kwd>
        <kwd>anxiety</kwd>
        <kwd>reproductive technologies</kwd>
        <kwd>fetal health</kwd>
        <kwd>epistemology</kwd>
        <kwd>ethics</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec sec-type="introduction">
      <title>Introduction</title>
      <p>Pregnancy is a time full of uncertainties [<xref ref-type="bibr" rid="ref1">1</xref>], starting from uncertainties concerning the health of the fetus and pregnant person, to parental uncertainties about how life will change during pregnancy and after birth, to socioeconomic uncertainties [<xref ref-type="bibr" rid="ref2">2</xref>,<xref ref-type="bibr" rid="ref3">3</xref>]. These uncertainties can be very challenging and can cause fear and anxiety among those affected [<xref ref-type="bibr" rid="ref4">4</xref>]. Smart health monitoring technologies (SHMTs) offer the possibility to continuously monitor the health of both the child and the mother, allowing parents to at least mitigate some health-related uncertainties, thereby alleviating associated stress and anxiety.</p>
      <p>But are SHMTs actually an effective means to reduce uncertainties during pregnancy, or do they have the opposite effect? In this Viewpoint, I will explore this question at a conceptual level and argue that while SHMTs can indeed reduce some health uncertainties, their use may also introduce new ones.</p>
      <p>The argument is developed as follows: First, I define the concept of uncertainty, drawing on relevant theories of uncertainty. Then, using conceptual reasoning supported by existing research, I theorize how pregnancy screenings can address certain uncertainties and how SHMTs can alleviate the remaining ones. Following this, I adopt a phenomenological approach to examine how the introduction of these technologies could create new uncertainties. This analysis is underpinned by key studies identified from database searches on PubMed, Embase, Web of Science, and Google Scholar using the keywords “pregnancy” and “uncertainty.” Finally, I reflect on the implications and limitations of these insights and provide practical recommendations based on pragmatic considerations.</p>
    </sec>
    <sec>
      <title>Uncertainties in the Context of Pregnancy</title>
      <p>Both in common sense and in the scientific discussion of this concept, uncertainty is largely understood as an epistemic state [<xref ref-type="bibr" rid="ref5">5</xref>,<xref ref-type="bibr" rid="ref6">6</xref>] in which individuals lack knowledge because they either lack information or the available information is inaccurate or incorrect [<xref ref-type="bibr" rid="ref7">7</xref>]. Many people experience uncertainty as a challenge, which can lead to stress, anxiety, and fear [<xref ref-type="bibr" rid="ref8">8</xref>]. A well-established method to navigate these uncertainties and alleviate the ensuing negative emotions involves bridging these knowledge gaps [<xref ref-type="bibr" rid="ref9">9</xref>].</p>
      <p>In the realm of health, uncertainty is nearly ubiquitous [<xref ref-type="bibr" rid="ref10">10</xref>-<xref ref-type="bibr" rid="ref12">12</xref>]. Even among those with a solid grasp of their bodily functions and biological processes, there remain gaps in knowledge and looming questions: What will my health look like tomorrow, next week, or a year from now [<xref ref-type="bibr" rid="ref13">13</xref>]? What steps can I take to prolong my well-being? The same can be said for pregnancy [<xref ref-type="bibr" rid="ref14">14</xref>], as pregnant women undergo significant physical and psychological changes and are constantly confronted with uncertainty [<xref ref-type="bibr" rid="ref15">15</xref>] regarding whether the fetus is developing healthily, whether there are signs of potential health issues, whether they are behaving correctly, or whether they need to make changes to promote the healthy development of the fetus [<xref ref-type="bibr" rid="ref3">3</xref>]. Pregnancy, an inherently stressful period, can be further complicated by these uncertainties, potentially escalating stress and anxiety levels in expectant mothers [<xref ref-type="bibr" rid="ref15">15</xref>], which may adversely affect both the parent and child [<xref ref-type="bibr" rid="ref16">16</xref>,<xref ref-type="bibr" rid="ref17">17</xref>]. Therefore, it is crucial to mitigate these uncertainties where feasible, to minimize unnecessary stressors.</p>
    </sec>
    <sec>
      <title>Pregnancy Screenings to Address Health-Related Uncertainties</title>
      <p>Thankfully, expectant parents are not helpless in the face of these health-related uncertainties. Various prenatal tests and screenings routinely conducted throughout pregnancy can provide insight into the health of both the pregnant individual and the fetus, thereby helping to alleviate existing uncertainties.</p>
      <p>Pregnancy screenings typically involve monitoring the vital signs of the pregnant person, including blood pressure, heart rate, and weight [<xref ref-type="bibr" rid="ref18">18</xref>]. By tracking weight gain, health care providers can assess the health of both the pregnant person and fetus, as inadequate weight gain may be harmful to the fetus, while rapid or excessive weight gain may be a sign of health concerns [<xref ref-type="bibr" rid="ref19">19</xref>,<xref ref-type="bibr" rid="ref20">20</xref>], such as gestational diabetes [<xref ref-type="bibr" rid="ref21">21</xref>,<xref ref-type="bibr" rid="ref22">22</xref>] or pre-eclampsia [<xref ref-type="bibr" rid="ref23">23</xref>]. A pregnant person’s heart rate and blood pressure can also provide valuable information, with a low maternal heart rate potentially negatively affecting fetal growth and birth weight of the fetus [<xref ref-type="bibr" rid="ref24">24</xref>,<xref ref-type="bibr" rid="ref25">25</xref>], while high blood pressure or an abnormal heart rate is associated with increased risks of gestational diabetes [<xref ref-type="bibr" rid="ref26">26</xref>] and maybe a sign of future cardiovascular disease [<xref ref-type="bibr" rid="ref27">27</xref>,<xref ref-type="bibr" rid="ref28">28</xref>]. Monitoring these vital signs is crucial for safeguarding the health of both the pregnant person and fetus, enabling timely interventions if necessary, and ultimately reducing health-related uncertainties during pregnancy.</p>
    </sec>
    <sec>
      <title>Smart Health Monitoring Technologies to Address These Uncertainties</title>
      <p>Although pregnancy screenings are vital for ensuring the health of both the pregnant person and the fetus, weeks can pass between appointments. During this time, pregnant individuals may find themselves grappling with everyday uncertainties, such as the effects of dietary changes or physical activities on the fetus, and seeking reassurance about both their own well-being and that of their unborn child.</p>
      <p>SHMTs such as smartwatches, smart rings, and fitness trackers, especially when integrated within an Internet of Things ecosystem [<xref ref-type="bibr" rid="ref29">29</xref>,<xref ref-type="bibr" rid="ref30">30</xref>], can offer a practical solution [<xref ref-type="bibr" rid="ref31">31</xref>-<xref ref-type="bibr" rid="ref33">33</xref>]. These devices enable parents to independently measure the vital signs of the pregnant person and, in some cases, the fetus at home. This data can be analyzed to provide parents with an assessment of their fetus’s health condition without needing to visit a doctor. The capability to ascertain the health status of their fetus from the comfort of home, or to receive timely alerts if the data points to potential health issues, could provide much-needed reassurance in between medical screenings and counter emerging uncertainties.</p>
    </sec>
    <sec>
      <title>New Uncertainties Produced by the Use of Smart Health Monitoring Technologies</title>
      <p>The widespread acceptance of SHMTs among expectant parents [<xref ref-type="bibr" rid="ref34">34</xref>], coupled with the fact that their use is considered extremely feasible by them [<xref ref-type="bibr" rid="ref35">35</xref>], as well as the empirical evidence suggesting that their use can have a positive impact on the health of pregnant persons [<xref ref-type="bibr" rid="ref36">36</xref>] and can reduce their stress levels [<xref ref-type="bibr" rid="ref37">37</xref>], should not obscure the fact that their use also brings some disadvantages. In addition to privacy and data protection issues [<xref ref-type="bibr" rid="ref38">38</xref>,<xref ref-type="bibr" rid="ref39">39</xref>], the use of SHMTs can also produce new health-related uncertainties.</p>
      <p>First, new information can in itself produce new uncertainties [<xref ref-type="bibr" rid="ref40">40</xref>], particularly when there are no medical personnel available to help interpret the additional data. In the absence of such guidance, every recorded irregularity, whether it be an irregular heartbeat, temporary high blood pressure, or a decrease in blood oxygen saturation, can cause pregnant persons to question their own health and that of their child. In extreme cases, these uncertainties can lead to unnecessary anxiety and stress symptoms [<xref ref-type="bibr" rid="ref41">41</xref>,<xref ref-type="bibr" rid="ref42">42</xref>], which can be detrimental to their mental and emotional well-being.</p>
      <p>However, even in professional contexts, more data might produce new uncertainties. This happens, for example, when continuous health monitoring triggers false alarms [<xref ref-type="bibr" rid="ref43">43</xref>], as, for instance, particular vital sign patterns are erroneously interpreted as symptoms of a specific disease or indicators of an emergency, despite being totally harmless. As Welch et al explain in their publication <italic>Overdiagnosed</italic> [<xref ref-type="bibr" rid="ref44">44</xref>], the likelihood of such false-positive diagnoses inevitably increases with additional data collection, which can lead to unnecessary or even incorrect diagnoses and create additional health uncertainties.</p>
      <p>Last, there is the uncertainty of whether health data are being collected accurately and analyzed correctly. Users of SHMTs must ask themselves if the sensors are properly attached, if smart devices are being used correctly, and if the data are being transmitted and analyzed correctly by the app’s algorithms [<xref ref-type="bibr" rid="ref45">45</xref>]. Particularly for medical and technical “laypeople,” there is no way to verify this, and they must live with the uncertainty about the reliability of the data.</p>
    </sec>
    <sec>
      <title>Ambivalent Effects of Pregnancy Monitoring Technologies</title>
      <p>I have shown how SHMTs can mitigate the daily health uncertainties encountered during pregnancy. However, it is important to note that the use of SHMTs during pregnancy can also create new uncertainties as they make even the slightest abnormalities visible, increase the likelihood of false-positive results, and raise constant questions about the reliability of the data.</p>
      <p>In summary, the use of SHMTs should be viewed as a double-edged sword. While they can help alleviate health uncertainties and reassure and relax pregnant persons, they also carry the risk of introducing new uncertainties, potentially exacerbating stress, anxiety, and fear.</p>
    </sec>
    <sec>
      <title>Limitations and Opportunities for Further Research</title>
      <p>The discussion regarding the correlation between SHMTs and uncertainties during pregnancy highlights 2 significant limitations. While these limitations require careful consideration, they do not invalidate the fundamental insights. Rather, they should be interpreted as avenues for further investigation.</p>
      <p>First, I did not present original data to substantiate my arguments. Although I have incorporated recent literature to substantiate key assumptions, and empirical research on uncertainty in pregnancy [<xref ref-type="bibr" rid="ref46">46</xref>] and on the impact of (health) technologies on uncertainty [<xref ref-type="bibr" rid="ref47">47</xref>] support my findings, my contribution was strictly conceptual.</p>
      <p>Second, the results do not explore the balance between the emergence of new uncertainties and the resolution of preexisting ones. Does the use of SHMTs produce more health uncertainties than it reduces, or vice versa? This question cannot be answered definitively, as shifts in uncertainty resulting from the use of such technologies need to be assessed on a case-by-case basis.</p>
    </sec>
    <sec>
      <title>Practical Recommendations</title>
      <p>In conclusion, the question arises of what practical recommendations can be derived from the insights gained regarding the use of SHMTs during pregnancy. Considering the preceding discussions, I recommend not to use SHMTs in terms of “the more the better,” as their increased use might also produce more uncertainties. Instead, it seems advisable to use them sparingly and only where constant monitoring is actually necessary [<xref ref-type="bibr" rid="ref10">10</xref>], such as when abnormalities have been identified during pregnancy screening or when there are hereditary medical conditions. In cases where constant monitoring is not necessary, these technologies should only be used upon explicit request from parents and with appropriate training on their use and data interpretation.</p>
      <p>Moreover, even if it may sound cynical at first, a pragmatic approach toward uncertainties in health care (not just during pregnancy) can be helpful and should be encouraged [<xref ref-type="bibr" rid="ref11">11</xref>,<xref ref-type="bibr" rid="ref48">48</xref>-<xref ref-type="bibr" rid="ref51">51</xref>]. This involves acknowledging that not everything can be controlled and that sometimes it can be beneficial to simply let things “take their course” [<xref ref-type="bibr" rid="ref52">52</xref>,<xref ref-type="bibr" rid="ref53">53</xref>].</p>
    </sec>
  </body>
  <back>
    <app-group/>
    <glossary>
      <title>Abbreviations</title>
      <def-list>
        <def-item>
          <term id="abb1">SHMTs</term>
          <def>
            <p>smart health monitoring technologies</p>
          </def>
        </def-item>
      </def-list>
    </glossary>
    <ack>
      <p>This work has been funded by Bundesministerium für Bildung und Forschung (grant 01GP2202B) and by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation)-SFB 1483, under project ID 442419336, EmpkinS. The author conveys his thanks to Hannah Bleher for her input and discussions, as well as to Isabella Auer, Fiona Bendig, and Tabea Ott. ChatGPT was used as a tool for idea generation in the early stages of this paper and for linguistically refining the final document. The content suggestions provided by ChatGPT were verified for accuracy and relevance by the author and were developed into a coherent manuscript by the author without the help of ChatGPT.</p>
    </ack>
    <fn-group>
      <fn fn-type="conflict">
        <p>None declared.</p>
      </fn>
    </fn-group>
    <ref-list>
      <ref id="ref1">
        <label>1</label>
        <nlm-citation citation-type="book">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Coxon</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Scamell</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Alaszewski</surname>
              <given-names>A</given-names>
            </name>
          </person-group>
          <source>Risk, Pregnancy and Childbirth</source>
          <year>2018</year>
          <publisher-loc>Milton Park, NY</publisher-loc>
          <publisher-name>Routledge</publisher-name>
        </nlm-citation>
      </ref>
      <ref id="ref2">
        <label>2</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Sorenson</surname>
              <given-names>DL</given-names>
            </name>
          </person-group>
          <article-title>Uncertainty in pregnancy</article-title>
          <source>NAACOGS Clin Issu Perinat Womens Health Nurs</source>
          <year>1990</year>
          <volume>1</volume>
          <issue>3</issue>
          <fpage>289</fpage>
          <lpage>96</lpage>
          <pub-id pub-id-type="medline">2206747</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref3">
        <label>3</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Affonso</surname>
              <given-names>DD</given-names>
            </name>
            <name name-style="western">
              <surname>Liu-Chiang</surname>
              <given-names>CY</given-names>
            </name>
            <name name-style="western">
              <surname>Mayberry</surname>
              <given-names>LJ</given-names>
            </name>
          </person-group>
          <article-title>Worry: conceptual dimensions and relevance to childbearing women</article-title>
          <source>Health Care Women Int</source>
          <year>1999</year>
          <volume>20</volume>
          <issue>3</issue>
          <fpage>227</fpage>
          <lpage>236</lpage>
          <pub-id pub-id-type="doi">10.1080/073993399245728</pub-id>
          <pub-id pub-id-type="medline">10633621</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref4">
        <label>4</label>
        <nlm-citation citation-type="web">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Reeves</surname>
              <given-names>N</given-names>
            </name>
          </person-group>
          <article-title>Common fears and anxiety during pregnancy</article-title>
          <source>Naître et Grandir</source>
          <year>2020</year>
          <access-date>2024-03-14</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://naitreetgrandir.com/fr/grossesse/sante-bien-etre/anxiety-pregnancy/">https://naitreetgrandir.com/fr/grossesse/sante-bien-etre/anxiety-pregnancy/</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref5">
        <label>5</label>
        <nlm-citation citation-type="book">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Anker</surname>
              <given-names>M</given-names>
            </name>
          </person-group>
          <source>The Ethics of Uncertainty: Aporetic Openings</source>
          <year>2009</year>
          <month>01</month>
          <day>15</day>
          <publisher-loc>New York, NY</publisher-loc>
          <publisher-name>Atropos Press</publisher-name>
        </nlm-citation>
      </ref>
      <ref id="ref6">
        <label>6</label>
        <nlm-citation citation-type="book">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Wittgenstein</surname>
              <given-names>L</given-names>
            </name>
          </person-group>
          <person-group person-group-type="editor">
            <name name-style="western">
              <surname>Anscombe</surname>
              <given-names>GEM</given-names>
            </name>
            <name name-style="western">
              <surname>von Wright</surname>
              <given-names>GH</given-names>
            </name>
          </person-group>
          <source>On Certainty</source>
          <year>1969</year>
          <publisher-loc>Oxford, UK</publisher-loc>
          <publisher-name>Basil Blackwell</publisher-name>
        </nlm-citation>
      </ref>
      <ref id="ref7">
        <label>7</label>
        <nlm-citation citation-type="book">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Smithson</surname>
              <given-names>M</given-names>
            </name>
          </person-group>
          <source>Ignorance and Uncertainty: Emerging Paradigms</source>
          <year>1989</year>
          <publisher-loc>New York, NY</publisher-loc>
          <publisher-name>Springer</publisher-name>
        </nlm-citation>
      </ref>
      <ref id="ref8">
        <label>8</label>
        <nlm-citation citation-type="book">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Bauman</surname>
              <given-names>Z</given-names>
            </name>
          </person-group>
          <source>Liquid Times: Living  in an Age of Uncertainty</source>
          <year>2007</year>
          <publisher-loc>Malden, MA</publisher-loc>
          <publisher-name>Polity</publisher-name>
        </nlm-citation>
      </ref>
      <ref id="ref9">
        <label>9</label>
        <nlm-citation citation-type="book">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Dewey</surname>
              <given-names>J</given-names>
            </name>
          </person-group>
          <source>The Quest for Certainty: a Study of the Relation of Knowledge and Action</source>
          <year>1929</year>
          <publisher-loc>London, UK</publisher-loc>
          <publisher-name>George Allen &amp; Unwin</publisher-name>
        </nlm-citation>
      </ref>
      <ref id="ref10">
        <label>10</label>
        <nlm-citation citation-type="book">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Hatch</surname>
              <given-names>S</given-names>
            </name>
          </person-group>
          <source>Snowball in a Blizzard: a Physician's Notes on uncertainty in Medicine</source>
          <year>2016</year>
          <publisher-loc>New York, NY</publisher-loc>
          <publisher-name>Basic Books</publisher-name>
        </nlm-citation>
      </ref>
      <ref id="ref11">
        <label>11</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Hatch</surname>
              <given-names>S</given-names>
            </name>
          </person-group>
          <article-title>Uncertainty in medicine</article-title>
          <source>BMJ</source>
          <year>2017</year>
          <volume>357</volume>
          <fpage>j2180</fpage>
          <pub-id pub-id-type="doi">10.1136/bmj.j2180</pub-id>
          <pub-id pub-id-type="medline">28495912</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref12">
        <label>12</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Mackintosh</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Armstrong</surname>
              <given-names>N</given-names>
            </name>
          </person-group>
          <article-title>Understanding and managing uncertainty in health care: revisiting and advancing sociological contributions</article-title>
          <source>Sociol Health Illn</source>
          <year>2020</year>
          <volume>42</volume>
          <issue>Suppl 1</issue>
          <fpage>1</fpage>
          <lpage>20</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://onlinelibrary.wiley.com/doi/10.1111/1467-9566.13160"/>
          </comment>
          <pub-id pub-id-type="doi">10.1111/1467-9566.13160</pub-id>
          <pub-id pub-id-type="medline">32757281</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref13">
        <label>13</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Gillespie</surname>
              <given-names>C</given-names>
            </name>
          </person-group>
          <article-title>The experience of risk as 'measured vulnerability': health screening and lay uses of numerical risk</article-title>
          <source>Sociol Health Illn</source>
          <year>2012</year>
          <volume>34</volume>
          <issue>2</issue>
          <fpage>194</fpage>
          <lpage>207</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://onlinelibrary.wiley.com/doi/10.1111/j.1467-9566.2011.01381.x"/>
          </comment>
          <pub-id pub-id-type="doi">10.1111/j.1467-9566.2011.01381.x</pub-id>
          <pub-id pub-id-type="medline">21848989</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref14">
        <label>14</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Matthias</surname>
              <given-names>MS</given-names>
            </name>
          </person-group>
          <article-title>Problematic integration in pregnancy and childbirth: contrasting approaches to uncertainty and desire in obstetric and midwifery care</article-title>
          <source>Health Commun</source>
          <year>2009</year>
          <volume>24</volume>
          <issue>1</issue>
          <fpage>60</fpage>
          <lpage>70</lpage>
          <pub-id pub-id-type="doi">10.1080/10410230802607008</pub-id>
          <pub-id pub-id-type="medline">19204859</pub-id>
          <pub-id pub-id-type="pii">908584322</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref15">
        <label>15</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>de Wolff</surname>
              <given-names>MG</given-names>
            </name>
            <name name-style="western">
              <surname>Rom</surname>
              <given-names>AL</given-names>
            </name>
            <name name-style="western">
              <surname>Johansen</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Broberg</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Midtgaard</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Tabor</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Hegaard</surname>
              <given-names>HK</given-names>
            </name>
          </person-group>
          <article-title>Worries among pregnant Danish women with chronic medical conditions—a cross sectional study with data from the Copenhagen pregnancy cohort</article-title>
          <source>Sex Reprod Healthc</source>
          <year>2021</year>
          <volume>29</volume>
          <fpage>100623</fpage>
          <pub-id pub-id-type="doi">10.1016/j.srhc.2021.100623</pub-id>
          <pub-id pub-id-type="medline">33984666</pub-id>
          <pub-id pub-id-type="pii">S1877-5756(21)00030-6</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref16">
        <label>16</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Dunkel Schetter</surname>
              <given-names>C</given-names>
            </name>
          </person-group>
          <article-title>Psychological science on pregnancy: stress processes, biopsychosocial models, and emerging research issues</article-title>
          <source>Annu Rev Psychol</source>
          <year>2011</year>
          <volume>62</volume>
          <fpage>531</fpage>
          <lpage>558</lpage>
          <pub-id pub-id-type="doi">10.1146/annurev.psych.031809.130727</pub-id>
          <pub-id pub-id-type="medline">21126184</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref17">
        <label>17</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Krishnamurti</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Davis</surname>
              <given-names>AL</given-names>
            </name>
            <name name-style="western">
              <surname>Simhan</surname>
              <given-names>HN</given-names>
            </name>
          </person-group>
          <article-title>Worrying yourself sick? association between pre-eclampsia onset and health-related worry in pregnancy</article-title>
          <source>Pregnancy Hypertens</source>
          <year>2019</year>
          <volume>18</volume>
          <fpage>55</fpage>
          <lpage>57</lpage>
          <pub-id pub-id-type="doi">10.1016/j.preghy.2019.09.003</pub-id>
          <pub-id pub-id-type="medline">31525710</pub-id>
          <pub-id pub-id-type="pii">S2210-7789(19)30351-4</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref18">
        <label>18</label>
        <nlm-citation citation-type="web">
          <article-title>Routine tests during pregnancy</article-title>
          <source>American College of Obtetricians and Gynecologists</source>
          <year>2021</year>
          <access-date>2023-04-25</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.acog.org/womens-health/faqs/routine-tests-during-pregnancy">https://www.acog.org/womens-health/faqs/routine-tests-during-pregnancy</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref19">
        <label>19</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Oken</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Kleinman</surname>
              <given-names>KP</given-names>
            </name>
            <name name-style="western">
              <surname>Belfort</surname>
              <given-names>MB</given-names>
            </name>
            <name name-style="western">
              <surname>Hammitt</surname>
              <given-names>JK</given-names>
            </name>
            <name name-style="western">
              <surname>Gillman</surname>
              <given-names>MW</given-names>
            </name>
          </person-group>
          <article-title>Associations of gestational weight gain with short- and longer-term maternal and child health outcomes</article-title>
          <source>Am J Epidemiol</source>
          <year>2009</year>
          <volume>170</volume>
          <issue>2</issue>
          <fpage>173</fpage>
          <lpage>180</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://europepmc.org/abstract/MED/19439579"/>
          </comment>
          <pub-id pub-id-type="doi">10.1093/aje/kwp101</pub-id>
          <pub-id pub-id-type="medline">19439579</pub-id>
          <pub-id pub-id-type="pii">kwp101</pub-id>
          <pub-id pub-id-type="pmcid">PMC2727269</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref20">
        <label>20</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Champion</surname>
              <given-names>ML</given-names>
            </name>
            <name name-style="western">
              <surname>Harper</surname>
              <given-names>LM</given-names>
            </name>
          </person-group>
          <article-title>Gestational weight gain: update on outcomes and interventions</article-title>
          <source>Curr Diab Rep</source>
          <year>2020</year>
          <volume>20</volume>
          <issue>3</issue>
          <fpage>11</fpage>
          <pub-id pub-id-type="doi">10.1007/s11892-020-1296-1</pub-id>
          <pub-id pub-id-type="medline">32108283</pub-id>
          <pub-id pub-id-type="pii">10.1007/s11892-020-1296-1</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref21">
        <label>21</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <collab>LifeCycle Project-Maternal Obesity and Childhood Outcomes Study Group</collab>
            <name name-style="western">
              <surname>Voerman</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Santos</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Inskip</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Amiano</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Barros</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Charles</surname>
              <given-names>MA</given-names>
            </name>
            <name name-style="western">
              <surname>Chatzi</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Chrousos</surname>
              <given-names>GP</given-names>
            </name>
            <name name-style="western">
              <surname>Corpeleijn</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Crozier</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Doyon</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Eggesbø</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Fantini</surname>
              <given-names>MP</given-names>
            </name>
            <name name-style="western">
              <surname>Farchi</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Forastiere</surname>
              <given-names>F</given-names>
            </name>
            <name name-style="western">
              <surname>Georgiu</surname>
              <given-names>V</given-names>
            </name>
            <name name-style="western">
              <surname>Gori</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Hanke</surname>
              <given-names>W</given-names>
            </name>
            <name name-style="western">
              <surname>Hertz-Picciotto</surname>
              <given-names>I</given-names>
            </name>
            <name name-style="western">
              <surname>Heude</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Hivert</surname>
              <given-names>MF</given-names>
            </name>
            <name name-style="western">
              <surname>Hryhorczuk</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Iñiguez</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Karvonen</surname>
              <given-names>AM</given-names>
            </name>
            <name name-style="western">
              <surname>Küpers</surname>
              <given-names>LK</given-names>
            </name>
            <name name-style="western">
              <surname>Lagström</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Lawlor</surname>
              <given-names>DA</given-names>
            </name>
            <name name-style="western">
              <surname>Lehmann</surname>
              <given-names>I</given-names>
            </name>
            <name name-style="western">
              <surname>Magnus</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Majewska</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Mäkelä</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Manios</surname>
              <given-names>Y</given-names>
            </name>
            <name name-style="western">
              <surname>Mommers</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Morgen</surname>
              <given-names>CS</given-names>
            </name>
            <name name-style="western">
              <surname>Moschonis</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Nohr</surname>
              <given-names>EA</given-names>
            </name>
            <name name-style="western">
              <surname>Andersen</surname>
              <given-names>AMN</given-names>
            </name>
            <name name-style="western">
              <surname>Oken</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Pac</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Papadopoulou</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Pekkanen</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Pizzi</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Polanska</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Porta</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Richiardi</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Rifas-Shiman</surname>
              <given-names>SL</given-names>
            </name>
            <name name-style="western">
              <surname>Roeleveld</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Ronfani</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Santos</surname>
              <given-names>AC</given-names>
            </name>
            <name name-style="western">
              <surname>Standl</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Stigum</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Stoltenberg</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Thiering</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Thijs</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Torrent</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Trnovec</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>van Gelder</surname>
              <given-names>MMHJ</given-names>
            </name>
            <name name-style="western">
              <surname>van Rossem</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>von Berg</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Vrijheid</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Wijga</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Zvinchuk</surname>
              <given-names>O</given-names>
            </name>
            <name name-style="western">
              <surname>Sørensen</surname>
              <given-names>TIA</given-names>
            </name>
            <name name-style="western">
              <surname>Godfrey</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Jaddoe</surname>
              <given-names>VWV</given-names>
            </name>
            <name name-style="western">
              <surname>Gaillard</surname>
              <given-names>R</given-names>
            </name>
          </person-group>
          <article-title>Association of gestational weight gain with adverse maternal and infant outcomes</article-title>
          <source>JAMA</source>
          <year>2019</year>
          <volume>321</volume>
          <issue>17</issue>
          <fpage>1702</fpage>
          <lpage>1715</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://europepmc.org/abstract/MED/31063572"/>
          </comment>
          <pub-id pub-id-type="doi">10.1001/jama.2019.3820</pub-id>
          <pub-id pub-id-type="medline">31063572</pub-id>
          <pub-id pub-id-type="pii">2732571</pub-id>
          <pub-id pub-id-type="pmcid">PMC6506886</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref22">
        <label>22</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Peng</surname>
              <given-names>Y</given-names>
            </name>
            <name name-style="western">
              <surname>Han</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Su</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Zhou</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Bao</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Ji</surname>
              <given-names>Y</given-names>
            </name>
            <name name-style="western">
              <surname>Luo</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Liu</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Wang</surname>
              <given-names>HJ</given-names>
            </name>
          </person-group>
          <article-title>Gestational weight gain and the risk of gestational diabetes mellitus: a latent class trajectory analysis using birth cohort data</article-title>
          <source>Diabetes Res Clin Pract</source>
          <year>2021</year>
          <volume>182</volume>
          <fpage>109130</fpage>
          <pub-id pub-id-type="doi">10.1016/j.diabres.2021.109130</pub-id>
          <pub-id pub-id-type="medline">34774643</pub-id>
          <pub-id pub-id-type="pii">S0168-8227(21)00489-7</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref23">
        <label>23</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Perry</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Stephanou</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Rayman</surname>
              <given-names>MP</given-names>
            </name>
          </person-group>
          <article-title>Dietary factors that affect the risk of pre-eclampsia</article-title>
          <source>BMJ Nutr Prev Health</source>
          <year>2022</year>
          <volume>5</volume>
          <issue>1</issue>
          <fpage>118</fpage>
          <lpage>133</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://europepmc.org/abstract/MED/35814725"/>
          </comment>
          <pub-id pub-id-type="doi">10.1136/bmjnph-2021-000399</pub-id>
          <pub-id pub-id-type="medline">35814725</pub-id>
          <pub-id pub-id-type="pii">bmjnph-2021-000399</pub-id>
          <pub-id pub-id-type="pmcid">PMC9237898</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref24">
        <label>24</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Odendaal</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Kieser</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Nel</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Brink</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>du Plessis</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Groenewald</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Lucchini</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Fifer</surname>
              <given-names>WP</given-names>
            </name>
            <name name-style="western">
              <surname>Myers</surname>
              <given-names>MM</given-names>
            </name>
          </person-group>
          <article-title>Effects of low maternal heart rate on fetal growth and birthweight</article-title>
          <source>Int J Gynaecol Obstet</source>
          <year>2019</year>
          <volume>146</volume>
          <issue>2</issue>
          <fpage>250</fpage>
          <lpage>256</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://europepmc.org/abstract/MED/31131885"/>
          </comment>
          <pub-id pub-id-type="doi">10.1002/ijgo.12873</pub-id>
          <pub-id pub-id-type="medline">31131885</pub-id>
          <pub-id pub-id-type="pmcid">PMC6610713</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref25">
        <label>25</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Huang</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Liu</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Huang</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>He</surname>
              <given-names>JR</given-names>
            </name>
            <name name-style="western">
              <surname>Wang</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Wang</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Feng</surname>
              <given-names>X</given-names>
            </name>
            <name name-style="western">
              <surname>Kuang</surname>
              <given-names>Y</given-names>
            </name>
            <name name-style="western">
              <surname>Lu</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Gu</surname>
              <given-names>Y</given-names>
            </name>
            <name name-style="western">
              <surname>Xia</surname>
              <given-names>X</given-names>
            </name>
            <name name-style="western">
              <surname>Lin</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Zhou</surname>
              <given-names>W</given-names>
            </name>
            <name name-style="western">
              <surname>Fu</surname>
              <given-names>Q</given-names>
            </name>
            <name name-style="western">
              <surname>Xia</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Qiu</surname>
              <given-names>X</given-names>
            </name>
          </person-group>
          <article-title>The born in Guangzhou cohort study enables generational genetic discoveries</article-title>
          <source>Nature</source>
          <year>2024</year>
          <volume>626</volume>
          <issue>7999</issue>
          <fpage>565</fpage>
          <lpage>573</lpage>
          <pub-id pub-id-type="doi">10.1038/s41586-023-06988-4</pub-id>
          <pub-id pub-id-type="medline">38297123</pub-id>
          <pub-id pub-id-type="pii">10.1038/s41586-023-06988-4</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref26">
        <label>26</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Hedderson</surname>
              <given-names>MM</given-names>
            </name>
            <name name-style="western">
              <surname>Ferrara</surname>
              <given-names>A</given-names>
            </name>
          </person-group>
          <article-title>High blood pressure before and during early pregnancy is associated with an increased risk of gestational diabetes mellitus</article-title>
          <source>Diabetes Care</source>
          <year>2008</year>
          <volume>31</volume>
          <issue>12</issue>
          <fpage>2362</fpage>
          <lpage>2367</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://europepmc.org/abstract/MED/18809624"/>
          </comment>
          <pub-id pub-id-type="doi">10.2337/dc08-1193</pub-id>
          <pub-id pub-id-type="medline">18809624</pub-id>
          <pub-id pub-id-type="pii">dc08-1193</pub-id>
          <pub-id pub-id-type="pmcid">PMC2584196</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref27">
        <label>27</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Tooher</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Chiu</surname>
              <given-names>CL</given-names>
            </name>
            <name name-style="western">
              <surname>Yeung</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Lupton</surname>
              <given-names>SJ</given-names>
            </name>
            <name name-style="western">
              <surname>Thornton</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Makris</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>O'Loughlin</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Hennessy</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Lind</surname>
              <given-names>JM</given-names>
            </name>
          </person-group>
          <article-title>High blood pressure during pregnancy is associated with future cardiovascular disease: an observational cohort study</article-title>
          <source>BMJ Open</source>
          <year>2013</year>
          <volume>3</volume>
          <issue>7</issue>
          <fpage>e002964</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://bmjopen.bmj.com/lookup/pmidlookup?view=long&amp;pmid=23883883"/>
          </comment>
          <pub-id pub-id-type="doi">10.1136/bmjopen-2013-002964</pub-id>
          <pub-id pub-id-type="medline">23883883</pub-id>
          <pub-id pub-id-type="pii">bmjopen-2013-002964</pub-id>
          <pub-id pub-id-type="pmcid">PMC3731716</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref28">
        <label>28</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Lo</surname>
              <given-names>CCW</given-names>
            </name>
            <name name-style="western">
              <surname>Lo</surname>
              <given-names>ACQ</given-names>
            </name>
            <name name-style="western">
              <surname>Leow</surname>
              <given-names>SH</given-names>
            </name>
            <name name-style="western">
              <surname>Fisher</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Corker</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Batho</surname>
              <given-names>O</given-names>
            </name>
            <name name-style="western">
              <surname>Morris</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Chowaniec</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Vladutiu</surname>
              <given-names>CJ</given-names>
            </name>
            <name name-style="western">
              <surname>Fraser</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Oliver-Williams</surname>
              <given-names>C</given-names>
            </name>
          </person-group>
          <article-title>Future cardiovascular disease risk for women with gestational hypertension: a systematic review and meta-analysis</article-title>
          <source>J Am Heart Assoc</source>
          <year>2020</year>
          <volume>9</volume>
          <issue>13</issue>
          <fpage>e013991</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.ahajournals.org/doi/10.1161/JAHA.119.013991?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub  0pubmed"/>
          </comment>
          <pub-id pub-id-type="doi">10.1161/JAHA.119.013991</pub-id>
          <pub-id pub-id-type="medline">32578465</pub-id>
          <pub-id pub-id-type="pmcid">PMC7670531</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref29">
        <label>29</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Venkatasubramanian</surname>
              <given-names>S</given-names>
            </name>
          </person-group>
          <article-title>Ambulatory monitoring of maternal and fetal using deep convolution generative adversarial network for smart health care IoT system</article-title>
          <source>Int J Adv Comput Sci Appl</source>
          <year>2022</year>
          <volume>13</volume>
          <issue>1</issue>
          <fpage>214</fpage>
          <lpage>222</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://thesai.org/Publications/ViewPaper?Volume=13&amp;Issue=1&amp;Code=IJACSA&amp;SerialNo=26"/>
          </comment>
          <pub-id pub-id-type="doi">10.14569/ijacsa.2022.0130126</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref30">
        <label>30</label>
        <nlm-citation citation-type="confproc">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Ahmed</surname>
              <given-names>LJ</given-names>
            </name>
            <name name-style="western">
              <surname>Madhumitha</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Mehana sree</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Oviya</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Sharmila</surname>
              <given-names>M</given-names>
            </name>
          </person-group>
          <article-title>A survey of IoT based pregnancy woman health monitoring system</article-title>
          <year>2022</year>
          <conf-name>2022 8th International Conference on Advanced Computing and Communication Systems (ICACCS)</conf-name>
          <conf-date>March 25-26, 2022</conf-date>
          <conf-loc>Coimbatore, India</conf-loc>
          <fpage>25</fpage>
          <lpage>26</lpage>
          <pub-id pub-id-type="doi">10.1109/icaccs54159.2022.9785324</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref31">
        <label>31</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Prabhu</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Malha</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Riley</surname>
              <given-names>LE</given-names>
            </name>
          </person-group>
          <article-title>Self-monitoring of blood pressure during pregnancy</article-title>
          <source>JAMA</source>
          <year>2022</year>
          <volume>327</volume>
          <issue>17</issue>
          <fpage>1651</fpage>
          <lpage>1652</lpage>
          <pub-id pub-id-type="doi">10.1001/jama.2022.2802</pub-id>
          <pub-id pub-id-type="medline">35503365</pub-id>
          <pub-id pub-id-type="pii">2791717</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref32">
        <label>32</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Schramm</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Grassl</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Nees</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Hoffmann</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Stepan</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Bruckner</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Haun</surname>
              <given-names>MW</given-names>
            </name>
            <name name-style="western">
              <surname>Maatouk</surname>
              <given-names>I</given-names>
            </name>
            <name name-style="western">
              <surname>Haist</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Schott</surname>
              <given-names>TC</given-names>
            </name>
            <name name-style="western">
              <surname>Sohn</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Schott</surname>
              <given-names>S</given-names>
            </name>
          </person-group>
          <article-title>Women's attitudes toward self-monitoring of their pregnancy using noninvasive electronic devices: cross-sectional multicenter study</article-title>
          <source>JMIR Mhealth Uhealth</source>
          <year>2019</year>
          <volume>7</volume>
          <issue>1</issue>
          <fpage>e11458</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://mhealth.jmir.org/2019/1/e11458/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/11458</pub-id>
          <pub-id pub-id-type="medline">30617040</pub-id>
          <pub-id pub-id-type="pii">v7i1e11458</pub-id>
          <pub-id pub-id-type="pmcid">PMC6329419</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref33">
        <label>33</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Runkle</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Sugg</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Boase</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Galvin</surname>
              <given-names>SL</given-names>
            </name>
            <name name-style="western">
              <surname>Coulson</surname>
              <given-names>CC</given-names>
            </name>
          </person-group>
          <article-title>Use of wearable sensors for pregnancy health and environmental monitoring: descriptive findings from the perspective of patients and providers</article-title>
          <source>Digit Health</source>
          <year>2019</year>
          <volume>5</volume>
          <fpage>2055207619828220</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://journals.sagepub.com/doi/10.1177/2055207619828220?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub  0pubmed"/>
          </comment>
          <pub-id pub-id-type="doi">10.1177/2055207619828220</pub-id>
          <pub-id pub-id-type="medline">30792878</pub-id>
          <pub-id pub-id-type="pii">10.1177_2055207619828220</pub-id>
          <pub-id pub-id-type="pmcid">PMC6376550</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref34">
        <label>34</label>
        <nlm-citation citation-type="confproc">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Li</surname>
              <given-names>X</given-names>
            </name>
            <name name-style="western">
              <surname>Lu</surname>
              <given-names>Y</given-names>
            </name>
            <name name-style="western">
              <surname>Shi</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Zhu</surname>
              <given-names>X</given-names>
            </name>
            <name name-style="western">
              <surname>Fu</surname>
              <given-names>X</given-names>
            </name>
          </person-group>
          <article-title>The impact of healthcare monitoring technologies for better pregnancy</article-title>
          <year>2021</year>
          <conf-name>2021 IEEE 4th International Conference on Electronics Technology (ICET)</conf-name>
          <conf-date>May 07-10, 2021</conf-date>
          <conf-loc>Chengdu, China</conf-loc>
          <fpage>7</fpage>
          <lpage>10</lpage>
          <pub-id pub-id-type="doi">10.1109/icet51757.2021.9450980</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref35">
        <label>35</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Zielinska</surname>
              <given-names>AP</given-names>
            </name>
            <name name-style="western">
              <surname>Mullins</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Lees</surname>
              <given-names>C</given-names>
            </name>
          </person-group>
          <article-title>The feasibility of multimodality remote monitoring of maternal physiology during pregnancy</article-title>
          <source>Medicine (Baltimore)</source>
          <year>2022</year>
          <volume>101</volume>
          <issue>26</issue>
          <fpage>e29566</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://europepmc.org/abstract/MED/35777056"/>
          </comment>
          <pub-id pub-id-type="doi">10.1097/MD.0000000000029566</pub-id>
          <pub-id pub-id-type="medline">35777056</pub-id>
          <pub-id pub-id-type="pii">00005792-202207010-00073</pub-id>
          <pub-id pub-id-type="pmcid">PMC9239642</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref36">
        <label>36</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Bertini</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Gárate</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Pardo</surname>
              <given-names>F</given-names>
            </name>
            <name name-style="western">
              <surname>Pelicand</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Sobrevia</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Torres</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Chabert</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Salas</surname>
              <given-names>R</given-names>
            </name>
          </person-group>
          <article-title>Impact of remote monitoring technologies for assisting patients with gestational diabetes mellitus: a systematic review</article-title>
          <source>Front Bioeng Biotechnol</source>
          <year>2022</year>
          <volume>10</volume>
          <fpage>819697</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://europepmc.org/abstract/MED/35310000"/>
          </comment>
          <pub-id pub-id-type="doi">10.3389/fbioe.2022.819697</pub-id>
          <pub-id pub-id-type="medline">35310000</pub-id>
          <pub-id pub-id-type="pii">819697</pub-id>
          <pub-id pub-id-type="pmcid">PMC8929763</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref37">
        <label>37</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Auxier</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Asgari Mehrabadi</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Rahmani</surname>
              <given-names>AM</given-names>
            </name>
            <name name-style="western">
              <surname>Axelin</surname>
              <given-names>A</given-names>
            </name>
          </person-group>
          <article-title>A descriptive comparative pilot study: association between use of a self-monitoring device and sleep and stress outcomes in pregnancy</article-title>
          <source>Comput Inform Nurs</source>
          <year>2023</year>
          <volume>41</volume>
          <issue>6</issue>
          <fpage>457</fpage>
          <lpage>466</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://europepmc.org/abstract/MED/36730074"/>
          </comment>
          <pub-id pub-id-type="doi">10.1097/CIN.0000000000000958</pub-id>
          <pub-id pub-id-type="medline">36730074</pub-id>
          <pub-id pub-id-type="pii">00024665-202306000-00013</pub-id>
          <pub-id pub-id-type="pmcid">PMC10241436</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref38">
        <label>38</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Willcox</surname>
              <given-names>JC</given-names>
            </name>
            <name name-style="western">
              <surname>van der Pligt</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Ball</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Wilkinson</surname>
              <given-names>SA</given-names>
            </name>
            <name name-style="western">
              <surname>Lappas</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>McCarthy</surname>
              <given-names>EA</given-names>
            </name>
            <name name-style="western">
              <surname>Campbell</surname>
              <given-names>KJ</given-names>
            </name>
          </person-group>
          <article-title>Views of women and health professionals on mHealth lifestyle interventions in pregnancy: a qualitative investigation</article-title>
          <source>JMIR Mhealth Uhealth</source>
          <year>2015</year>
          <volume>3</volume>
          <issue>4</issue>
          <fpage>e99</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://mhealth.jmir.org/2015/4/e99/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/mhealth.4869</pub-id>
          <pub-id pub-id-type="medline">26510886</pub-id>
          <pub-id pub-id-type="pii">v3i4e99</pub-id>
          <pub-id pub-id-type="pmcid">PMC4704935</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref39">
        <label>39</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Overdijkink</surname>
              <given-names>SB</given-names>
            </name>
            <name name-style="western">
              <surname>Velu</surname>
              <given-names>AV</given-names>
            </name>
            <name name-style="western">
              <surname>Rosman</surname>
              <given-names>AN</given-names>
            </name>
            <name name-style="western">
              <surname>van Beukering</surname>
              <given-names>MD</given-names>
            </name>
            <name name-style="western">
              <surname>Kok</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Steegers-Theunissen</surname>
              <given-names>RP</given-names>
            </name>
          </person-group>
          <article-title>The usability and effectiveness of mobile health technology-based lifestyle and medical intervention apps supporting health care during pregnancy: systematic review</article-title>
          <source>JMIR Mhealth Uhealth</source>
          <year>2018</year>
          <volume>6</volume>
          <issue>4</issue>
          <fpage>e109</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://mhealth.jmir.org/2018/4/e109/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/mhealth.8834</pub-id>
          <pub-id pub-id-type="medline">29691216</pub-id>
          <pub-id pub-id-type="pii">v6i4e109</pub-id>
          <pub-id pub-id-type="pmcid">PMC5941088</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref40">
        <label>40</label>
        <nlm-citation citation-type="book">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Wallerstein</surname>
              <given-names>I</given-names>
            </name>
          </person-group>
          <source>The Uncertainties of Knowledge</source>
          <year>2004</year>
          <publisher-loc>Philadelphia, PA</publisher-loc>
          <publisher-name>Temple University Press</publisher-name>
        </nlm-citation>
      </ref>
      <ref id="ref41">
        <label>41</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Wakefield</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Yao</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Self</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Frasch</surname>
              <given-names>MG</given-names>
            </name>
          </person-group>
          <article-title>Wearable technology for health monitoring during pregnancy: an observational cross-sectional survey study</article-title>
          <source>Arch Gynecol Obstet</source>
          <year>2023</year>
          <volume>308</volume>
          <issue>1</issue>
          <fpage>73</fpage>
          <lpage>78</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://europepmc.org/abstract/MED/35831759"/>
          </comment>
          <pub-id pub-id-type="doi">10.1007/s00404-022-06705-y</pub-id>
          <pub-id pub-id-type="medline">35831759</pub-id>
          <pub-id pub-id-type="pii">10.1007/s00404-022-06705-y</pub-id>
          <pub-id pub-id-type="pmcid">PMC9281287</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref42">
        <label>42</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Marteau</surname>
              <given-names>TM</given-names>
            </name>
          </person-group>
          <article-title>Towards informed decisions about prenatal testing: a review</article-title>
          <source>Prenat Diagn</source>
          <year>1995</year>
          <volume>15</volume>
          <issue>13</issue>
          <fpage>1215</fpage>
          <lpage>1226</lpage>
          <pub-id pub-id-type="doi">10.1002/pd.1970151304</pub-id>
          <pub-id pub-id-type="medline">8710763</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref43">
        <label>43</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Downey</surname>
              <given-names>CL</given-names>
            </name>
            <name name-style="western">
              <surname>Chapman</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Randell</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Brown</surname>
              <given-names>JM</given-names>
            </name>
            <name name-style="western">
              <surname>Jayne</surname>
              <given-names>DG</given-names>
            </name>
          </person-group>
          <article-title>The impact of continuous versus intermittent vital signs monitoring in hospitals: a systematic review and narrative synthesis</article-title>
          <source>Int J Nurs Stud</source>
          <year>2018</year>
          <volume>84</volume>
          <fpage>19</fpage>
          <lpage>27</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://eprints.whiterose.ac.uk/130735/"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/j.ijnurstu.2018.04.013</pub-id>
          <pub-id pub-id-type="medline">29729558</pub-id>
          <pub-id pub-id-type="pii">S0020-7489(18)30098-1</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref44">
        <label>44</label>
        <nlm-citation citation-type="book">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Welch</surname>
              <given-names>HG</given-names>
            </name>
            <name name-style="western">
              <surname>Schwartz</surname>
              <given-names>LM</given-names>
            </name>
            <name name-style="western">
              <surname>Woloshin</surname>
              <given-names>S</given-names>
            </name>
          </person-group>
          <source>Overdiagnosed: Making People Sick in the Pursuit of Health</source>
          <year>2011</year>
          <publisher-loc>Boston, MA</publisher-loc>
          <publisher-name>Beacon Press</publisher-name>
        </nlm-citation>
      </ref>
      <ref id="ref45">
        <label>45</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Hariri</surname>
              <given-names>RH</given-names>
            </name>
            <name name-style="western">
              <surname>Fredericks</surname>
              <given-names>EM</given-names>
            </name>
            <name name-style="western">
              <surname>Bowers</surname>
              <given-names>KM</given-names>
            </name>
          </person-group>
          <article-title>Uncertainty in big data analytics: survey, opportunities, and challenges</article-title>
          <source>J Big Data</source>
          <year>2019</year>
          <volume>6</volume>
          <issue>1</issue>
          <fpage>44</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://journalofbigdata.springeropen.com/articles/10.1186/s40537-019-0206-3"/>
          </comment>
          <pub-id pub-id-type="doi">10.1186/s40537-019-0206-3</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref46">
        <label>46</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Matthias</surname>
              <given-names>MS</given-names>
            </name>
            <name name-style="western">
              <surname>Babrow</surname>
              <given-names>AS</given-names>
            </name>
          </person-group>
          <article-title>Problematic integration of uncertainty and desire in pregnancy</article-title>
          <source>Qual Health Res</source>
          <year>2007</year>
          <volume>17</volume>
          <issue>6</issue>
          <fpage>786</fpage>
          <lpage>798</lpage>
          <pub-id pub-id-type="doi">10.1177/1049732307303241</pub-id>
          <pub-id pub-id-type="medline">17582021</pub-id>
          <pub-id pub-id-type="pii">17/6/786</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref47">
        <label>47</label>
        <nlm-citation citation-type="book">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Zvonareva</surname>
              <given-names>O</given-names>
            </name>
            <name name-style="western">
              <surname>Popova</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Horstman</surname>
              <given-names>K</given-names>
            </name>
          </person-group>
          <source>Health, Technologies, and Politics in Post-Soviet Settings: Navigating Uncertainties</source>
          <year>2018</year>
          <publisher-loc>London, UK</publisher-loc>
          <publisher-name>Palgrave Macmillan</publisher-name>
        </nlm-citation>
      </ref>
      <ref id="ref48">
        <label>48</label>
        <nlm-citation citation-type="book">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Christoffersen</surname>
              <given-names>MG</given-names>
            </name>
          </person-group>
          <source>Living with Risk and Danger: Studies in Interdisciplinary Systematic Theology</source>
          <year>2019</year>
          <publisher-loc>Göttingen, Germany</publisher-loc>
          <publisher-name>Vandenhoeck and Ruprecht</publisher-name>
        </nlm-citation>
      </ref>
      <ref id="ref49">
        <label>49</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Rogers</surname>
              <given-names>WA</given-names>
            </name>
            <name name-style="western">
              <surname>Walker</surname>
              <given-names>MJ</given-names>
            </name>
          </person-group>
          <article-title>Fragility, uncertainty, and healthcare</article-title>
          <source>Theor Med Bioeth</source>
          <year>2016</year>
          <volume>37</volume>
          <issue>1</issue>
          <fpage>71</fpage>
          <lpage>83</lpage>
          <pub-id pub-id-type="doi">10.1007/s11017-016-9350-3</pub-id>
          <pub-id pub-id-type="medline">26906556</pub-id>
          <pub-id pub-id-type="pii">10.1007/s11017-016-9350-3</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref50">
        <label>50</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Simpkin</surname>
              <given-names>AL</given-names>
            </name>
            <name name-style="western">
              <surname>Schwartzstein</surname>
              <given-names>RM</given-names>
            </name>
          </person-group>
          <article-title>Tolerating uncertainty—the next medical revolution?</article-title>
          <source>N Engl J Med</source>
          <year>2016</year>
          <volume>375</volume>
          <issue>18</issue>
          <fpage>1713</fpage>
          <lpage>1715</lpage>
          <pub-id pub-id-type="doi">10.1056/NEJMp1606402</pub-id>
          <pub-id pub-id-type="medline">27806221</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref51">
        <label>51</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Tretter</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Ott</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Dabrock</surname>
              <given-names>P</given-names>
            </name>
          </person-group>
          <article-title>AI-produced certainties in health care: current and future challenges</article-title>
          <source>AI Ethics</source>
          <year>2023</year>
          <month>11</month>
          <day>21</day>
          <pub-id pub-id-type="doi">10.1007/s43681-023-00374-6</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref52">
        <label>52</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Seely</surname>
              <given-names>AJ</given-names>
            </name>
          </person-group>
          <article-title>Embracing the certainty of uncertainty: implications for health care and research</article-title>
          <source>Perspect Biol Med</source>
          <year>2013</year>
          <volume>56</volume>
          <issue>1</issue>
          <fpage>65</fpage>
          <lpage>77</lpage>
          <pub-id pub-id-type="doi">10.1353/pbm.2013.0009</pub-id>
          <pub-id pub-id-type="medline">23748527</pub-id>
          <pub-id pub-id-type="pii">S1529879513100047</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref53">
        <label>53</label>
        <nlm-citation citation-type="book">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Han</surname>
              <given-names>PKJ</given-names>
            </name>
          </person-group>
          <source>Uncertainty in Medicine: a Framework for Tolerance</source>
          <year>2021</year>
          <publisher-loc>New York, NY</publisher-loc>
          <publisher-name>Oxford University Press</publisher-name>
        </nlm-citation>
      </ref>
    </ref-list>
  </back>
</article>
