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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JMIR</journal-id>
      <journal-id journal-id-type="nlm-ta">J Med Internet Res</journal-id>
      <journal-title>Journal of Medical Internet Research</journal-title>
      <issn pub-type="epub">1438-8871</issn>
      <publisher>
        <publisher-name>JMIR Publications</publisher-name>
        <publisher-loc>Toronto, Canada</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">v25i1e47670</article-id>
      <article-id pub-id-type="pmid">37494087</article-id>
      <article-id pub-id-type="doi">10.2196/47670</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Short Paper</subject>
        </subj-group>
        <subj-group subj-group-type="article-type">
          <subject>Short Paper</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Impact of Telemedicine Modality on Quality Metrics in Diverse Settings: Implementation Science–Informed Retrospective Cohort Study</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="editor">
          <name>
            <surname>Leung</surname>
            <given-names>Tiffany</given-names>
          </name>
        </contrib>
        <contrib contrib-type="editor">
          <name>
            <surname>de Azevedo Cardoso</surname>
            <given-names>Taiane</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Cornelis</surname>
            <given-names>Justien</given-names>
          </name>
        </contrib>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Tierney</surname>
            <given-names>Aaron</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib id="contrib1" contrib-type="author">
          <name name-style="western">
            <surname>Rome</surname>
            <given-names>Danielle</given-names>
          </name>
          <degrees>MD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0009-0002-0945-3156</ext-link>
        </contrib>
        <contrib id="contrib2" contrib-type="author">
          <name name-style="western">
            <surname>Sales</surname>
            <given-names>Alyssa</given-names>
          </name>
          <degrees>BA</degrees>
          <xref rid="aff2" ref-type="aff">2</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-6597-0433</ext-link>
        </contrib>
        <contrib id="contrib3" contrib-type="author">
          <name name-style="western">
            <surname>Cornelius</surname>
            <given-names>Talea</given-names>
          </name>
          <degrees>PhD, MSW, MS</degrees>
          <xref rid="aff3" ref-type="aff">3</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0001-7181-0981</ext-link>
        </contrib>
        <contrib id="contrib4" contrib-type="author">
          <name name-style="western">
            <surname>Malhotra</surname>
            <given-names>Sujata</given-names>
          </name>
          <degrees>MD, MPH</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0009-0009-2689-9396</ext-link>
        </contrib>
        <contrib id="contrib5" contrib-type="author">
          <name name-style="western">
            <surname>Singer</surname>
            <given-names>Jessica</given-names>
          </name>
          <degrees>MD, MPH</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-0503-6892</ext-link>
        </contrib>
        <contrib id="contrib6" contrib-type="author">
          <name name-style="western">
            <surname>Ye</surname>
            <given-names>Siqin</given-names>
          </name>
          <degrees>MD, MS</degrees>
          <xref rid="aff3" ref-type="aff">3</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-5229-9775</ext-link>
        </contrib>
        <contrib id="contrib7" contrib-type="author" corresp="yes">
          <name name-style="western">
            <surname>Moise</surname>
            <given-names>Nathalie</given-names>
          </name>
          <degrees>MD, MS</degrees>
          <xref rid="aff3" ref-type="aff">3</xref>
          <address>
            <institution>Center for Behavioral Cardiovascular Health</institution>
            <institution>Department of Medicine</institution>
            <institution>Columbia University Irving Medical Center</institution>
            <addr-line>622 W. 168th Street, PH9-317</addr-line>
            <addr-line>New York, NY, 10032</addr-line>
            <country>United States</country>
            <phone>1 212 342 2889</phone>
            <fax>1 212 342 3431</fax>
            <email>nm2562@cumc.columbia.edu</email>
          </address>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-5660-5573</ext-link>
        </contrib>
      </contrib-group>
      <aff id="aff1">
        <label>1</label>
        <institution>Department of Medicine</institution>
        <institution>Columbia University Irving Medical Center</institution>
        <addr-line>New York, NY</addr-line>
        <country>United States</country>
      </aff>
      <aff id="aff2">
        <label>2</label>
        <institution>Columbia University</institution>
        <addr-line>New York, NY</addr-line>
        <country>United States</country>
      </aff>
      <aff id="aff3">
        <label>3</label>
        <institution>Center for Behavioral Cardiovascular Health</institution>
        <institution>Department of Medicine</institution>
        <institution>Columbia University Irving Medical Center</institution>
        <addr-line>New York, NY</addr-line>
        <country>United States</country>
      </aff>
      <author-notes>
        <corresp>Corresponding Author: Nathalie Moise <email>nm2562@cumc.columbia.edu</email></corresp>
      </author-notes>
      <pub-date pub-type="collection">
        <year>2023</year>
      </pub-date>
      <pub-date pub-type="epub">
        <day>26</day>
        <month>7</month>
        <year>2023</year>
      </pub-date>
      <volume>25</volume>
      <elocation-id>e47670</elocation-id>
      <history>
        <date date-type="received">
          <day>28</day>
          <month>3</month>
          <year>2023</year>
        </date>
        <date date-type="rev-request">
          <day>24</day>
          <month>4</month>
          <year>2023</year>
        </date>
        <date date-type="rev-recd">
          <day>15</day>
          <month>5</month>
          <year>2023</year>
        </date>
        <date date-type="accepted">
          <day>31</day>
          <month>5</month>
          <year>2023</year>
        </date>
      </history>
      <copyright-statement>©Danielle Rome, Alyssa Sales, Talea Cornelius, Sujata Malhotra, Jessica Singer, Siqin Ye, Nathalie Moise. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 26.07.2023.</copyright-statement>
      <copyright-year>2023</copyright-year>
      <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
        <p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Journal of Medical Internet Research, is properly cited. The complete bibliographic information, a link to the original publication on https://www.jmir.org/, as well as this copyright and license information must be included.</p>
      </license>
      <self-uri xlink:href="https://www.jmir.org/2023/1/e47670" xlink:type="simple"/>
      <abstract>
        <sec sec-type="background">
          <title>Background</title>
          <p>Video-based telemedicine (vs audio only) is less frequently used in diverse, low socioeconomic status settings. Few prior studies have evaluated the impact of telemedicine modality (ie, video vs audio-only visits) on clinical quality metrics.</p>
        </sec>
        <sec sec-type="objective">
          <title>Objective</title>
          <p>The aim of this study was to assess telemedicine uptake and impact of visit modality (in-person vs video and phone visits) on primary care quality metrics in diverse, low socioeconomic status settings through an implementation science lens.</p>
        </sec>
        <sec sec-type="methods">
          <title>Methods</title>
          <p>Informed by the RE-AIM (Reach, Effectiveness, Adoption, Implementation, and Maintenance) framework, we evaluated telemedicine uptake, assessed targeted primary care quality metrics by visit modality, and described provider-level qualitative feedback on barriers and facilitators to telemedicine implementation.</p>
        </sec>
        <sec sec-type="results">
          <title>Results</title>
          <p>We found marginally better quality metrics (ie, blood pressure and depression screening) for in-person care versus video and phone visits; de-adoption of telemedicine was marked within 2 years in our population.</p>
        </sec>
        <sec sec-type="conclusions">
          <title>Conclusions</title>
          <p>Following the widespread implementation of telemedicine during the COVID-19 pandemic, the impact of visit modality on quality outcomes, provider and patient preferences, as well as technological barriers in historically marginalized settings should be considered.</p>
        </sec>
      </abstract>
      <kwd-group>
        <kwd>telemedicine</kwd>
        <kwd>telehealth</kwd>
        <kwd>implementation science</kwd>
        <kwd>quality metrics</kwd>
        <kwd>screening</kwd>
        <kwd>adoption</kwd>
        <kwd>diverse</kwd>
        <kwd>socioeconomic</kwd>
        <kwd>audio based</kwd>
        <kwd>video based</kwd>
        <kwd>video consultation</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec sec-type="introduction">
      <title>Introduction</title>
      <p>Following initial COVID-19 waves, the reintroduction of in-person care alongside telemedicine provided an opportunity to elucidate nuances in telemedicine implementation and assess its impact compared to in-person visits [<xref ref-type="bibr" rid="ref1">1</xref>]. Moreover, telemedicine expansion beyond the pandemic warrants evaluation of differences by modalities (ie, video-based vs audio-only telemedicine) [<xref ref-type="bibr" rid="ref2">2</xref>,<xref ref-type="bibr" rid="ref3">3</xref>].</p>
      <p>Research suggests that the addition of telemedicine (vs in-person care alone) may improve quality measures and clinical outcomes [<xref ref-type="bibr" rid="ref4">4</xref>-<xref ref-type="bibr" rid="ref7">7</xref>]. However, findings are inconsistent [<xref ref-type="bibr" rid="ref8">8</xref>,<xref ref-type="bibr" rid="ref9">9</xref>] and often exclude or cannot differentiate video from audio-only telemedicine, which is more frequently used in diverse, low socioeconomic status (SES) settings where digital literacy and access issues are known [<xref ref-type="bibr" rid="ref10">10</xref>-<xref ref-type="bibr" rid="ref13">13</xref>]. Although video visits (vs audio-only) may impact provider-level outcomes (ie, increased visit duration, number of diagnoses addressed, rates of medication, lab, and imaging orders) [<xref ref-type="bibr" rid="ref14">14</xref>,<xref ref-type="bibr" rid="ref15">15</xref>], few prior studies have examined the impact of video and audio-only versus in-person visits on quality metrics in low SES settings.</p>
      <p>To address these gaps, we used an implementation science framework and mixed methods approach to assess telemedicine uptake and the impact of modalities on primary care quality metrics in diverse, low SES settings.</p>
    </sec>
    <sec sec-type="methods">
      <title>Methods</title>
      <sec>
        <title>Study Population</title>
        <p>From November to December 2020, we conducted a retrospective cohort study of unique patient visits among 8 attending telemedicine champions (to ensure adequate distribution of modalities) at 3 primary care practices in an academic medical center in New York City serving a predominantly (&#62;80%) Medicaid population. We randomly selected 2-3 mixed-modality clinical sessions (ie, scheduled in-person, video, and phone visits) per provider. Included visits were follow-ups with established patients of attending primary care providers (PCPs); modality was determined by PCP recommendation or patient preference. We excluded other visit types (eg, same-day sick visits, new patient encounters, resident or trainee visits, and visits with nonestablished patients) to ensure that all visits were conducted by the patient’s PCP, allotted the same duration (~20 min), and used the same template in the electronic health record across modalities (<xref rid="figure1" ref-type="fig">Figure 1</xref>).</p>
        <fig id="figure1" position="float">
          <label>Figure 1</label>
          <caption>
            <p>Study population, outcomes, and statistical analyses. Patients were determined to be due for cancer screenings based on United States Preventive Services Task Force recommendations. BP: blood pressure; HbA<sub>1c</sub>: hemoglobin A<sub>1c</sub>; PHQ-2: Patient Health Questionnaire-2; RE-AIM: Reach, Effectiveness, Adoption, Implementation, and Maintenance; SES: socioeconomic status.</p>
          </caption>
          <graphic xlink:href="jmir_v25i1e47670_fig1.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
        </fig>
      </sec>
      <sec>
        <title>Study Outcomes</title>
        <p>Outcomes were informed by the RE-AIM (Reach, Effectiveness, Adoption, Implementation, and Maintenance) framework [<xref ref-type="bibr" rid="ref16">16</xref>]. We assessed <italic>reach</italic> (demographic differences by modality) and <italic>adoption</italic> (telemedicine uptake at the clinic, provider, and patient levels). For <italic>effectiveness,</italic> we identified United States Preventive Services Task Force and Accountable Care Organization quality metrics (ie, screening for blood pressure [BP], with BP&#60;140/90 mmHg; depression; hemoglobin A<sub>1c</sub> [HbA<sub>1c</sub>]; lipids; mammography; cervical cancer; and colorectal cancer). We then conducted retrospective chart reviews to assess at-visit BP and depression screening as well as HbA<sub>1c</sub>, lipid, and cancer screening orders. For <italic>implementation</italic>, we described conversion of video to phone visits and no-show rates. Given the ongoing pandemic, we obtained provider feedback on barriers and facilitators using rapid-cycle qualitative research methods to reduce time commitment and intensity of data collection required of providers and to inform real-time practice changes [<xref ref-type="bibr" rid="ref17">17</xref>,<xref ref-type="bibr" rid="ref18">18</xref>]. Following clinical sessions, providers were emailed a web-based form to input free-text narrative comments on barriers to and facilitators for each encounter; the form was returned 1-7 days after the visit (<xref ref-type="supplementary-material" rid="app1">Multimedia Appendix 1</xref>). For <italic>maintenance</italic>, we examined adoption rates in a random sample of visits identified using the same inclusion/exclusion criteria over an equivalent period, 2 years later (November-December 2022).</p>
      </sec>
      <sec>
        <title>Statistical Analysis</title>
        <sec>
          <title>Quantitative Analysis</title>
          <p>We used descriptive statistics and chi-square tests to describe demographic differences by modality, telemedicine uptake, conversion of video to phone visits, and no-show rates. To analyze the association between modality and quality metrics, we used a generalized linear mixed model with a binary outcome distribution and a logit link to allow for correlated errors to account for clustering by provider, adjusting for age, race, ethnicity, language (non-English vs English), Charlson Comorbidity Index [<xref ref-type="bibr" rid="ref19">19</xref>] (range 0.0-12.0), and prior telemedicine (ie, video and phone) visits (0 vs ≥1).</p>
        </sec>
        <sec>
          <title>Qualitative Analysis</title>
          <p>Informed by prior rapid-cycle qualitative analysis approaches, we focused on specific research questions on implementation (ie, telemedicine barriers and facilitators) [<xref ref-type="bibr" rid="ref20">20</xref>] and used the framework method to analyze free-text comments in Microsoft Excel [<xref ref-type="bibr" rid="ref18">18</xref>,<xref ref-type="bibr" rid="ref21">21</xref>,<xref ref-type="bibr" rid="ref22">22</xref>]. Following an unstructured familiarization phase, initial codes were developed, and in a subsequent coding phase, final themes were identified, with relevant qualitative data tabulated by theme.</p>
        </sec>
      </sec>
      <sec>
        <title>Ethical Considerations</title>
        <p>Ethics approval was obtained from the Columbia University Irving Medical Center Institutional Review Board (IRB-AAAR5570). A waiver for informed consent was granted given the retrospective nature of our study. All data were properly secured and stored in a manner compliant with HIPAA (Health Insurance Portability and Accountability Act) on an encrypted server.</p>
      </sec>
    </sec>
    <sec sec-type="results">
      <title>Results</title>
      <p>We identified 281 unique visits. Mean participant age was 63.3 (SD 15.1) years; 71.5% (201/281) were Hispanic, 15.3% (43/281) were Black, and 61.9% (174/281) were non-English speaking. Mean Charlson Comorbidity Index was 3.39 (SD 2.46).</p>
      <sec>
        <title>Reach and Adoption</title>
        <p>Overall, 24.6% (69/281) of the visits were in person, 25.3% (71/281) were through video, and 32.7% (92/281) through phone calls; 17.4% (49/281) were no-shows; 27.8% (78/281) of patients had no prior telemedicine visits. Patients aged ≥65 years (vs those aged &#60;65 years) were more likely to have in-person (46/69, 67% vs 23/69, 33%) and phone visits (52/92, 57% vs 40/92, 43%) and less likely to have video (26/71, 37% vs 45/71, 63%) and no-show visits (22/49, 45% vs 27/49, 55%; <italic>P</italic>=.002). Non-English–speaking patients (vs English-speaking patients) were marginally more likely to have in-person (45/69, 65% vs 24/69, 35%), phone (63/92, 68% vs 29/92, 32%), and no-show visits (31/49, 63% vs 18/49, 37%); the proportion of video visits was almost similar between the two groups (35/71, 49% vs 36/71, 51%; <italic>P</italic>=.08). PCP was significantly associated with modality (<italic>P</italic>&#60;.001). Clinic (<italic>P</italic>=.65), race (<italic>P</italic>=.39<italic>)</italic>, and ethnicity (<italic>P</italic>=.81) were not significantly associated with modality.</p>
      </sec>
      <sec>
        <title>Effectiveness</title>
        <p>We found marginally significant differences in BP screening for video (15/71, 21%), phone (16/92, 17%), and in-person (39/69, 57%) visits (adjusted <italic>P</italic>=.06), with significantly lower odds for video (adjusted odds ratio [AOR] 0.21, 95% CI 0.09-0.50; <italic>P</italic>&#60;.001) and phone (AOR 0.16, 95% CI 0.08-0.30; <italic>P</italic>&#60;.001) versus in-person visits. Similar trends emerged for depression screening (24/71, 34%; 12/92, 13%; and 41/69, 59%, respectively; adjusted <italic>P</italic>=.06), for video (AOR 0.35, 95% CI 0.14-0.86; <italic>P</italic>=.02) and phone (AOR 0.10, 95% CI 0.04-0.26; <italic>P</italic>&#60;.001) versus in-person visits. For HbA<sub>1c</sub> or lipid screening orders, we found significantly lower odds for phone versus in-person visits only (AOR 0.46, 95% CI 0.24-0.88; <italic>P=</italic>.02). We found no significant difference by modality for a combined metric of any cancer screening order (ie, mammography, colorectal cancer, or cervical cancer; <xref ref-type="table" rid="table1">Table 1</xref>).</p>
        <table-wrap position="float" id="table1">
          <label>Table 1</label>
          <caption>
            <p>Quality metrics by completed visit modality (n=232).</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="110"/>
            <col width="150"/>
            <col width="80"/>
            <col width="0"/>
            <col width="140"/>
            <col width="70"/>
            <col width="0"/>
            <col width="150"/>
            <col width="80"/>
            <col width="0"/>
            <col width="150"/>
            <col width="70"/>
            <thead>
              <tr valign="bottom">
                <td>Visit modality</td>
                <td colspan="3">Blood pressure screening<sup>a</sup></td>
                <td colspan="3">Depression screening<sup>b</sup></td>
                <td colspan="3">HbA<sub>1c</sub> or lipid screening<sup>c</sup></td>
                <td colspan="2">Cancer screening<sup>d</sup> (n=76)</td>
              </tr>
              <tr valign="bottom">
                <td>
                  <break/>
                </td>
                <td>AOR<sup>e</sup> (95% CI)</td>
                <td><italic>P</italic> value</td>
                <td colspan="2">AOR (95% CI)</td>
                <td><italic>P</italic> value</td>
                <td colspan="2">AOR (95% CI)</td>
                <td><italic>P</italic> value</td>
                <td colspan="2">AOR (95% CI)</td>
                <td><italic>P</italic> value</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td>Video vs in-person visit</td>
                <td>0.21 (0.09-0.50)</td>
                <td>&#60;.001</td>
                <td colspan="2">0.35 (0.14-0.86)</td>
                <td>.02</td>
                <td colspan="2">0.61 (0.27-1.36)</td>
                <td>.23</td>
                <td colspan="2">0.74 (0.11-5.00)</td>
                <td>.76</td>
              </tr>
              <tr valign="top">
                <td>Phone vs in-person visit</td>
                <td>0.16 (0.08-0.30)</td>
                <td>&#60;.001</td>
                <td colspan="2">0.10 (0.04-0.26)</td>
                <td>&#60;.001</td>
                <td colspan="2">0.46 (0.24-0.88)</td>
                <td>.02</td>
                <td colspan="2">0.55 (0.13-2.41)</td>
                <td>.43</td>
              </tr>
            </tbody>
          </table>
          <table-wrap-foot>
            <fn id="table1fn1">
              <p><sup>a</sup>Blood pressure (BP) documented at visit, with BP&#60;140/90 mmHg.</p>
            </fn>
            <fn id="table1fn2">
              <p><sup>b</sup>Patient Health Questionnaire-2 completed at visit.</p>
            </fn>
            <fn id="table1fn3">
              <p><sup>c</sup>Hemoglobin A<sub>1c</sub> (HbA<sub>1c</sub>) or lipid panel ordered at visit.</p>
            </fn>
            <fn id="table1fn4">
              <p><sup>d</sup>Mammography, colorectal cancer, or cervical cancer screening ordered at visit, if due.</p>
            </fn>
            <fn id="table1fn5">
              <p><sup>e</sup>AOR: adjusted odds ratio; AOR is adjusted for age, race, ethnicity, primary language (non-English vs English), Charlson Comorbidity Index, prior telemedicine (ie, video and phone) visits (0 vs ≥1), and clustering by provider.</p>
            </fn>
          </table-wrap-foot>
        </table-wrap>
      </sec>
      <sec>
        <title>Implementation</title>
        <p>Overall, 39.4% (56/142) of scheduled video visits converted to phone visits. We found no significant difference in no-show rates by modality (<italic>P</italic>=.17). Emerging themes included technological issues, patient preferences, and need for social support. Interpreters or relatives serving as translators were often identified as facilitators for non-English–speaking patients versus English-speaking patients (<xref ref-type="table" rid="table2">Table 2</xref>).</p>
        <table-wrap position="float" id="table2">
          <label>Table 2</label>
          <caption>
            <p>Provider-identified barriers and facilitators to telemedicine uptake.</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="30"/>
            <col width="0"/>
            <col width="440"/>
            <col width="0"/>
            <col width="0"/>
            <col width="530"/>
            <thead>
              <tr valign="top">
                <td colspan="4">Theme and category</td>
                <td colspan="2">Example quotes</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td colspan="6">
                  <bold>Barriers</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td colspan="2">Difficulty with technology setup</td>
                <td colspan="3">
                  <list list-type="bullet">
                    <list-item>
                      <p>“Does not know how to set up apps on smartphone”</p>
                    </list-item>
                    <list-item>
                      <p>“Low tech literacy”</p>
                    </list-item>
                    <list-item>
                      <p>“Couldn’t figure out log in”</p>
                    </list-item>
                    <list-item>
                      <p>“Patient is quite unfamiliar with technology, did not know what MyChart was…didn’t feel comfortable following the texted link to connect to Doximity video visit”</p>
                    </list-item>
                  </list>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td colspan="2">Lack of video-compatible device or technology</td>
                <td colspan="3">
                  <list list-type="bullet">
                    <list-item>
                      <p>“Patient does not own a smart phone, no household contacts with a smart phone”</p>
                    </list-item>
                    <list-item>
                      <p>“Only has landline”</p>
                    </list-item>
                    <list-item>
                      <p>“Lack of Wi-Fi access”</p>
                    </list-item>
                  </list>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td colspan="2">Patient preference for in-person visits</td>
                <td colspan="3">
                  <list list-type="bullet">
                    <list-item>
                      <p>“Really prefers in-person, feels like she gets better care”</p>
                    </list-item>
                    <list-item>
                      <p>“Very resistant to video/phone visit, doesn’t believe getting adequate care”</p>
                    </list-item>
                  </list>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td colspan="2">Patient preference for phone visits</td>
                <td colspan="3">
                  <list list-type="bullet">
                    <list-item>
                      <p>“Declined video, not comfortable with apps”</p>
                    </list-item>
                    <list-item>
                      <p>“Patient requested phone visit”</p>
                    </list-item>
                  </list>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td colspan="2">Video platform issues (eg, Epic-MyChart, Zoom, or Doximity)</td>
                <td colspan="3">
                  <list list-type="bullet">
                    <list-item>
                      <p>“Kept freezing when we tried Doximity and Epic/Zoom”</p>
                    </list-item>
                    <list-item>
                      <p>“Could not figure out Zoom/MyChart (we tried on 3 different cell phones before we were successful)”</p>
                    </list-item>
                    <list-item>
                      <p>“Doximity unsuccessful”</p>
                    </list-item>
                  </list>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td colspan="2">Poor connectivity</td>
                <td colspan="3">
                  <list list-type="bullet">
                    <list-item>
                      <p>“Poor connection on cellular network”</p>
                    </list-item>
                    <list-item>
                      <p>“Audio connectivity issues at the beginning of the call…video was a little grainy but still preferable to nothing.”</p>
                    </list-item>
                    <list-item>
                      <p>“Patient had terrible connectivity due to Wi-Fi connection (he lives in a shelter), he could not get the audio to work”</p>
                    </list-item>
                  </list>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td colspan="2">Inadequate social support or setting</td>
                <td colspan="3">
                  <list list-type="bullet">
                    <list-item>
                      <p>“Unstable social situation (living in a shelter with her two children)”</p>
                    </list-item>
                    <list-item>
                      <p>“Lives alone without younger family members to help navigate tech-based platforms”</p>
                    </list-item>
                    <list-item>
                      <p>“Limited privacy for video visit”</p>
                    </list-item>
                  </list>
                </td>
              </tr>
              <tr valign="top">
                <td colspan="6">
                  <bold>Facilitators</bold>
                </td>
              </tr>
              <tr valign="top">
                <td colspan="2">
                  <break/>
                </td>
                <td colspan="3">Assistance from a relative</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>“Son and niece helped coordinate call”</p>
                    </list-item>
                    <list-item>
                      <p>“Daughter had to patch patient in for a 3-way call”</p>
                    </list-item>
                    <list-item>
                      <p>“Son and niece helped coordinate call, also used an interpreter”</p>
                    </list-item>
                    <list-item>
                      <p>“Patient’s English-speaking daughter was next to her and helped her set-up”</p>
                    </list-item>
                  </list>
                </td>
              </tr>
              <tr valign="top">
                <td colspan="2">
                  <break/>
                </td>
                <td colspan="3">Technologic proficiency</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>“Very comfortable using technology”</p>
                    </list-item>
                    <list-item>
                      <p>“Has smartphone, digitally savvy”</p>
                    </list-item>
                    <list-item>
                      <p>“Patient is generally more tech-savvy…previously connected to MyChart for prior video visits both with me and with specialists; uses MyChart to check lab results and send messages”</p>
                    </list-item>
                  </list>
                </td>
              </tr>
            </tbody>
          </table>
        </table-wrap>
      </sec>
      <sec>
        <title>Maintenance</title>
        <p>After 2 years, the distribution of in-person, video, and phone visits was 90.2% (111/123), 7.3% (9/123), and 2.4% (3/123), respectively.</p>
      </sec>
    </sec>
    <sec sec-type="discussion">
      <title>Discussion</title>
      <sec>
        <title>Principal Findings</title>
        <p>After the first COVID-19 wave, we found similar distributions of in-person, video, and phone visits in low SES settings, with marginally better BP and depression screening for in-person care. De-adoption was marked within 2 years in our population.</p>
        <p>Research delineating audio-only telemedicine and quality metrics is limited [<xref ref-type="bibr" rid="ref5">5</xref>-<xref ref-type="bibr" rid="ref7">7</xref>]. Our mixed methods findings highlight competing, disruptive technological barriers (ie, over one-third of video visits converted to audio-only visits) in low SES settings, potentially impacting quality metrics. We particularly observed gaps in screenings supported by ancillary clinic staff during in-person rooming (eg, medical assistants routinely perform BP and depression screenings), which was unavailable for telemedicine in our setting. Prior research shows an association between medical assistant–supported virtual rooming and successful video visit connections [<xref ref-type="bibr" rid="ref23">23</xref>]; future studies should assess impact of virtual rooming on quality outcomes. Modality may be a proxy for other provider (eg, cognitive load, engagement, or shared decision-making) and patient factors (eg, transportation, access, or literacy), further impacting lab and cancer screening orders, which providers knew warranted travel. Some providers were more likely to use telemedicine, perhaps due to differences in preference, experience, or technologically savvy patient panels.</p>
        <p>Our qualitative findings support prior qualitative research on determinants of telemedicine and remote patient monitoring, expanding on perspectives in historically marginalized populations [<xref ref-type="bibr" rid="ref3">3</xref>,<xref ref-type="bibr" rid="ref24">24</xref>,<xref ref-type="bibr" rid="ref25">25</xref>]. Experts should examine whether addressing barriers (eg, technology access), promoting facilitators (eg, social support), and fine-tuning hybrid in-person and telemedicine models improve quality metrics and long-term telemedicine uptake. Future studies should assess within-modality differences in quality metrics by patient race, ethnicity, and language, given the documented disparities in telemedicine modality uptake. Special consideration is warranted for low-income settings, where in-person care equalizers may be unavailable (eg, video translator services, at-home labs, or device loan programs).</p>
      </sec>
      <sec>
        <title>Study Limitations</title>
        <p>Limitations include unmeasured differences between modalities, including visit quality (eg, nonverbal communication and patient-provider rapport) and duration. Our sample size likely impacted cancer screening results, as few patients were due for screening. We were unable to assess provider or patient modality preferences (eg, providers less comfortable with video-based telemedicine scheduling more phone visits, older patients preferring in-person care, and technologically savvy patients using video visits), though we adjusted for clustering by provider, patient demographics, and prior telemedicine use. Additionally, telemedicine champions were used to ensure adequate distribution of modalities, which introduces bias; gaps are likely wider, overall. Lastly, we only describe 2 snapshots in time, albeit our results suggest telemedicine de-adoption in our population. Modality preferences, technological barriers, and restructuring of clinic workflows following the pandemic may have contributed to the reversion to in-person care and should be assessed as potential drivers of de-adoption.</p>
      </sec>
      <sec>
        <title>Conclusions</title>
        <p>Proponents of widespread telemedicine implementation should consider telemedicine impact on quality outcomes, provider and patient preferences, and mitigating strategies in historically marginalized populations.</p>
      </sec>
    </sec>
  </body>
  <back>
    <app-group>
      <supplementary-material id="app1">
        <label>Multimedia Appendix 1</label>
        <p>Web-based form for rapid-cycle qualitative feedback from providers on barriers to and facilitators for telemedicine uptake and implementation.</p>
        <media xlink:href="jmir_v25i1e47670_app1.xlsx" xlink:title="XLSX File  (Microsoft Excel File), 10 KB"/>
      </supplementary-material>
    </app-group>
    <glossary>
      <title>Abbreviations</title>
      <def-list>
        <def-item>
          <term id="abb1">AOR</term>
          <def>
            <p>adjusted odds ratio</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb2">BP</term>
          <def>
            <p>blood pressure</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb3">HbA<sub>1c</sub></term>
          <def>
            <p>hemoglobin A<sub>1c</sub></p>
          </def>
        </def-item>
        <def-item>
          <term id="abb4">HIPAA</term>
          <def>
            <p>Health Insurance Portability and Accountability Act</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb5">PCP</term>
          <def>
            <p>primary care provider</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb6">RE-AIM</term>
          <def>
            <p>Reach, Effectiveness, Adoption, Implementation, and Maintenance</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb7">SES</term>
          <def>
            <p>socioeconomic status</p>
          </def>
        </def-item>
      </def-list>
    </glossary>
    <ack>
      <p>This work was supported by funds from the Agency for Health and Research Quality (AHRQ; R01HS025198). AHRQ had no role in the design and conduct of the study, including the collection, management, analysis, interpretation of the data, preparation, review or approval of the manuscript, and decision to submit the manuscript for publication.</p>
    </ack>
    <notes>
      <sec>
        <title>Data Availability</title>
        <p>The data sets generated and analyzed during this study are available from the corresponding author on reasonable request.</p>
      </sec>
    </notes>
    <fn-group>
      <fn fn-type="con">
        <p>DR and NM conceptualized and designed the study; DR and AS were in charge of data acquisition; data analysis and interpretation were conducted by DR and NM; DR and NM were also responsible for drafting the manuscript; the manuscript was critically revised for important intellectual content by NM, SY, JS, SM, and TC; statistical analysis was conducted by NM, TC, and DR; NM obtained funding for the study and supervised the study.</p>
      </fn>
      <fn fn-type="conflict">
        <p>None declared.</p>
      </fn>
    </fn-group>
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