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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JMIR</journal-id>
      <journal-id journal-id-type="nlm-ta">J Med Internet Res</journal-id>
      <journal-title>Journal of Medical Internet Research</journal-title>
      <issn pub-type="epub">1438-8871</issn>
      <publisher>
        <publisher-name>JMIR Publications</publisher-name>
        <publisher-loc>Toronto, Canada</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">v25i1e43102</article-id>
      <article-id pub-id-type="pmid">37129931</article-id>
      <article-id pub-id-type="doi">10.2196/43102</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Review</subject>
        </subj-group>
        <subj-group subj-group-type="article-type">
          <subject>Review</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Attitudes of Children, Adolescents, and Their Parents Toward Digital Health Interventions: Scoping Review</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="editor">
          <name>
            <surname>Leung</surname>
            <given-names>Tiffany</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Guinemer</surname>
            <given-names>Camille</given-names>
          </name>
        </contrib>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Beran</surname>
            <given-names>Tanya</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib id="contrib1" contrib-type="author" corresp="yes">
          <name name-style="western">
            <surname>d'Halluin</surname>
            <given-names>Arnaud</given-names>
          </name>
          <degrees>MD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <address>
            <institution>WHO Collaborating Centre for Research and Training in Mental Health</institution>
            <institution>EPSM Lille Métropole</institution>
            <addr-line>211 Rue Roger Salengro</addr-line>
            <addr-line>Lille - Hellemmes, 59260</addr-line>
            <country>France</country>
            <phone>33 3 20 43 71 00</phone>
            <email>arndhalluin59@gmail.com</email>
          </address>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0003-4470-7297</ext-link>
        </contrib>
        <contrib id="contrib2" contrib-type="author">
          <name name-style="western">
            <surname>Costa</surname>
            <given-names>Marie</given-names>
          </name>
          <degrees>PhD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <xref rid="aff2" ref-type="aff">2</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0001-7360-1921</ext-link>
        </contrib>
        <contrib id="contrib3" contrib-type="author">
          <name name-style="western">
            <surname>Morgiève</surname>
            <given-names>Margot</given-names>
          </name>
          <degrees>PhD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <xref rid="aff3" ref-type="aff">3</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-1305-3860</ext-link>
        </contrib>
        <contrib id="contrib4" contrib-type="author">
          <name name-style="western">
            <surname>Sebbane</surname>
            <given-names>Déborah</given-names>
          </name>
          <degrees>MD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <xref rid="aff2" ref-type="aff">2</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0001-5688-6515</ext-link>
        </contrib>
      </contrib-group>
      <aff id="aff1">
        <label>1</label>
        <institution>WHO Collaborating Centre for Research and Training in Mental Health</institution>
        <institution>EPSM Lille Métropole</institution>
        <addr-line>Lille - Hellemmes</addr-line>
        <country>France</country>
      </aff>
      <aff id="aff2">
        <label>2</label>
        <institution>Évaluation clinique épidémiologique-économique appliquée aux populations vulnérables</institution>
        <institution>Inserm</institution>
        <institution>Université Paris Cité</institution>
        <addr-line>Paris</addr-line>
        <country>France</country>
      </aff>
      <aff id="aff3">
        <label>3</label>
        <institution>Centre de recherche médecine, sciences, santé, santé mentale, société</institution>
        <institution>Inserm</institution>
        <institution>Université Paris Cité</institution>
        <addr-line>Paris</addr-line>
        <country>France</country>
      </aff>
      <author-notes>
        <corresp>Corresponding Author: Arnaud d'Halluin <email>arndhalluin59@gmail.com</email></corresp>
      </author-notes>
      <pub-date pub-type="collection">
        <year>2023</year>
      </pub-date>
      <pub-date pub-type="epub">
        <day>2</day>
        <month>5</month>
        <year>2023</year>
      </pub-date>
      <volume>25</volume>
      <elocation-id>e43102</elocation-id>
      <history>
        <date date-type="received">
          <day>29</day>
          <month>9</month>
          <year>2022</year>
        </date>
        <date date-type="rev-request">
          <day>4</day>
          <month>11</month>
          <year>2022</year>
        </date>
        <date date-type="rev-recd">
          <day>29</day>
          <month>1</month>
          <year>2023</year>
        </date>
        <date date-type="accepted">
          <day>8</day>
          <month>3</month>
          <year>2023</year>
        </date>
      </history>
      <copyright-statement>©Arnaud d'Halluin, Marie Costa, Margot Morgiève, Déborah Sebbane. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 02.05.2023.</copyright-statement>
      <copyright-year>2023</copyright-year>
      <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
        <p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Journal of Medical Internet Research, is properly cited. The complete bibliographic information, a link to the original publication on https://www.jmir.org/, as well as this copyright and license information must be included.</p>
      </license>
      <self-uri xlink:href="https://www.jmir.org/2023/1/e43102" xlink:type="simple"/>
      <abstract>
        <sec sec-type="background">
          <title>Background</title>
          <p>The prevalence of mental health problems in children and adolescents is high. As these problems can impact this population’s developmental trajectories, they constitute a public health concern. This situation is accentuated by the fact that children and adolescents infrequently seek help. Digital health interventions (DHIs) offer an opportunity to bridge the treatment gap between health care needs and patient engagement in care. Additional detailed research is needed to identify how children and adolescents can be empowered to access help through DHIs. In this context, an understanding of their attitudes toward digital health appears to be a necessary first step in facilitating the effective implementation of DHIs.</p>
        </sec>
        <sec sec-type="objective">
          <title>Objective</title>
          <p>This study aimed to establish an inventory of children’s, adolescents’, and their parents’ attitudes toward DHIs.</p>
        </sec>
        <sec sec-type="methods">
          <title>Methods</title>
          <p>A scoping review following PRISMA-ScR (Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews) recommendations was performed using the MEDLINE, Embase, and PsycINFO databases. This research was conducted using 3 key concepts: “child and adolescent mental health service users,” “digital health interventions,” and “attitudes.” Data extracted included the name of the publishing journal, the methodology used, the target population, the DHI studied, and the principal results.</p>
        </sec>
        <sec sec-type="results">
          <title>Results</title>
          <p>Of 1548 studies found, 30 (1.94%) were included in our analysis. Among these, 13 concerned satisfaction, 24 concerned preferences, 22 concerned the use of DHI, 11 concerned perception, and 10 concerned needs.</p>
        </sec>
        <sec sec-type="conclusions">
          <title>Conclusions</title>
          <p>The results of this study provide a better understanding of the factors influencing children’s and adolescents’ attitudes toward digital health and DHIs. The continued growth of DHIs can help reduce barriers to mental health care. Future research on these interventions should investigate the needs of the targeted populations to increase their engagement in care.</p>
        </sec>
      </abstract>
      <kwd-group>
        <kwd>eHealth</kwd>
        <kwd>mental health</kwd>
        <kwd>children and adolescents</kwd>
        <kwd>attitude</kwd>
        <kwd>scoping review</kwd>
        <kwd>mobile phone</kwd>
        <kwd>digital health intervention</kwd>
        <kwd>DHI</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec sec-type="introduction">
      <title>Introduction</title>
      <sec>
        <title>Background</title>
        <p>Mental health problems among children and adolescents can severely affect several areas of their life and developmental trajectories [<xref ref-type="bibr" rid="ref1">1</xref>]. Worldwide, the estimated prevalence of these problems in this population ranges from 10% to 20% [<xref ref-type="bibr" rid="ref2">2</xref>]. In 2015, an international meta-analysis found that the prevalence of mental health problems in children and young people was 13.4%, with the most frequent mental health problems being anxiety and disruptive behaviors [<xref ref-type="bibr" rid="ref3">3</xref>]. Mental health problems among children and adolescents constitute a public health issue, especially because they may be reluctant to seek professional help [<xref ref-type="bibr" rid="ref4">4</xref>,<xref ref-type="bibr" rid="ref5">5</xref>]. Reasons for not seeking help include the stigmatization of mental problems, lack of confidentiality and trust, stress associated with seeking help, fear of care providers, and no access to care [<xref ref-type="bibr" rid="ref5">5</xref>]. The growing interest in technology among children and adolescents may offer a unique opportunity to bridge what has been called the “treatment gap” between mental health care needs and care seeking in this population [<xref ref-type="bibr" rid="ref6">6</xref>].</p>
      </sec>
      <sec>
        <title>Digital Health Interventions in Mental Health</title>
        <p>Digital health interventions (DHIs) comprise web-based interventions, mobile apps, mobile text messages, virtual reality environments, and computer programs. They are easy to access and guarantee anonymity [<xref ref-type="bibr" rid="ref7">7</xref>]. Several public health organizations have recognized DHIs as a cost-effective, scalable solution to help solve the treatment gap for mental health problems [<xref ref-type="bibr" rid="ref8">8</xref>]. In 2015, a World Health Organization survey revealed that 29% of the 15,000 health apps surveyed focused on mental health diagnosis, treatment, or support, constituting a disproportionate and noncoordinated offer [<xref ref-type="bibr" rid="ref9">9</xref>]. Although many of these apps were evidence informed and were inspired by scientifically validated techniques and methods, very few were evidence based (ie, the subject of rigorous scientific studies demonstrating their effectiveness and reliability [<xref ref-type="bibr" rid="ref10">10</xref>,<xref ref-type="bibr" rid="ref11">11</xref>]). Most recently, lockdowns related to the COVID-19 health crisis forced mental health services to sharply increase their use of information and communications technology (ICT) to provide care, with a consequent acceleration in DHI implementation [<xref ref-type="bibr" rid="ref12">12</xref>]. However, despite this growing interest in eHealth, more research is needed to support the development and consequent implementation of DHI [<xref ref-type="bibr" rid="ref7">7</xref>].</p>
      </sec>
      <sec>
        <title>Research’s State of the Art</title>
        <p>Researchers have emphasized several limitations of their implementation, including poor patient engagement, high dropout rates, and interventions that are inadequately tailored to patients’ needs [<xref ref-type="bibr" rid="ref7">7</xref>,<xref ref-type="bibr" rid="ref13">13</xref>]. Engagement (also described as participation or adherence, whereas its absence is described as noncompliance or resistance) is commonly referred to as the active involvement of participants in an intervention [<xref ref-type="bibr" rid="ref14">14</xref>]. Recently, a meta-analysis found that engagement in DHIs by children and adolescents depended on “intervention-specific influences” (suitability, usability, and acceptability) and “person-specific influences” (motivation, opportunity, and the capability to use) [<xref ref-type="bibr" rid="ref7">7</xref>]. These influences should be considered when providing a DHI [<xref ref-type="bibr" rid="ref7">7</xref>]. Another systematic and meta-review found that children and adolescents with mental health problems who used DHIs expressed the need for them to be accessible and controllable and that they could be used with autonomy. It also suggested that their attitudes should be taken into account when designing a DHI [<xref ref-type="bibr" rid="ref15">15</xref>].</p>
        <p>Attitude is defined as “an enduring, learned predisposition to behave in a consistent way toward a given class of objects, or a persistent mental and neural state of readiness to react to a certain class of objects, not as they are, but as they are conceived to be” [<xref ref-type="bibr" rid="ref16">16</xref>]. It manifests both psychologically and sociologically as a subjective predisposition of what a person likes and a prescriptive judgment of what a person ought to do [<xref ref-type="bibr" rid="ref17">17</xref>]. Attitude can be measured using beliefs, emotions, and behaviors [<xref ref-type="bibr" rid="ref17">17</xref>]. Previous literature on attitudes toward DHIs found that it can reflect (1) acculturation to ICT and eHealth literacy, (2) trust or mistrust, and (3) resistance or predisposition to its use [<xref ref-type="bibr" rid="ref18">18</xref>,<xref ref-type="bibr" rid="ref19">19</xref>]. As attitude contains a priori notions about the DHI, it may directly affect engagement in these interventions.</p>
      </sec>
      <sec>
        <title>Objectives</title>
        <p>There is a scarcity of literature on attitudes of young people toward DHIs [<xref ref-type="bibr" rid="ref18">18</xref>]. In this context, we conducted a scoping review of the attitudes of children and adolescents with distressing mental experiences toward the DHI they had already used. Specifically, we aimed to create an inventory of children’s, adolescents’, and their parents’ attitudes toward DHIs, with the aim of acquiring a better understanding of young DHI users’ attitudes toward this technology and their engagement in it, as well as to guide future research in this field.</p>
      </sec>
    </sec>
    <sec sec-type="methods">
      <title>Methods</title>
      <sec>
        <title>Overview</title>
        <p>The protocol for this review followed the PRISMA-ScR (Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews) extension recommendations for scoping reviews [<xref ref-type="bibr" rid="ref20">20</xref>]. It was written in June 2021 by the French research team of the World Health Organization Collaborating Centre for Research and Training in Mental Health (Lille, France), which comprises a resident psychiatrist (AD), a researcher in public health (MC), a researcher in social sciences (MM), and a senior psychiatrist (DS). All the authors (AD, MC, MM, and DS) defined the search strategy, the inclusion and exclusion criteria, the selection process, and the data extraction method. The protocol was registered on the Open Science Framework [<xref ref-type="bibr" rid="ref21">21</xref>].</p>
      </sec>
      <sec>
        <title>Identifying Relevant Studies</title>
        <p>The search strategy consisted of identifying key concepts related to DHIs, targeted at children and adolescents, and how they were perceived by users. We developed a provisional syntax for each database to pretest and determine the definitive Boolean equation used. Boolean equations were structured around 3 domains: “digital mental health intervention,” “child or adolescent mental health service user,” and “attitude.” The keywords used came from everyday vocabulary and thesaurus terms.</p>
        <p>We used 3 databases, MEDLINE, Embase, and PsycINFO, which cover the fields of medicine, psychology, behavioral science, and DHIs. The results were filtered to retain only articles concerning children and adolescents, using MEDLINE’S age limits for children (0-18 years). The syntax and limits used for each database searched can be found in <xref ref-type="supplementary-material" rid="app1">Multimedia Appendix 1</xref>.</p>
      </sec>
      <sec>
        <title>Inclusion and Exclusion Criteria</title>
        <p>Studies had to be written in English and published between January 1, 2007 (the year when the first smartphone was released), and July 8, 2021 (the date of the last literature search). The study population in each study included children, adolescents, or their parents. Only studies whose primary objective was to explore DHI use by children or adolescents, their preferences, or their attitudes were included in the analysis. The following types of articles were excluded: (1) articles where the studied DHI only targeted parents of children, (2) articles that did not interview users but focused on the implementation of DHIs or on DHI efficacy studies, and (3) articles that only explored professional mental health care providers’ attitudes toward DHIs.</p>
      </sec>
      <sec>
        <title>Selecting Studies</title>
        <p>The first author (AD) selected the articles to be included and excluded. The search provided 1548 articles, 147 of which were duplicates. AD screened the titles and abstracts for eligibility using the free web tool RAYYAN. Of the 81 articles deemed eligible for a full reading, 51 were secondarily excluded by AD. The third (MM) and fourth (DS) authors read the remaining 30 articles and agreed to their inclusion. The authors met regularly during the selection process to clarify how the inclusion criteria were to be applied and to deliberate over the suitability of certain articles for inclusion. The selection process is presented in the PRISMA-ScR flowchart (<xref rid="figure1" ref-type="fig">Figure 1</xref>).</p>
        <fig id="figure1" position="float">
          <label>Figure 1</label>
          <caption>
            <p>PRISMA-ScR (Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews) flowchart. DHI: digital health intervention.</p>
          </caption>
          <graphic xlink:href="jmir_v25i1e43102_fig1.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
        </fig>
      </sec>
      <sec>
        <title>Data Extraction</title>
        <p>A Microsoft Excel spreadsheet was created to compile pertinent information from the selected articles. It included 15 items regarding general information (first author, year of publication, and country of publication), the methodology used (primary objective, research design, and type of data collection), the population concerned (type of recruitment, number, gender, and age of children or adolescents concerned and the number and gender of parents), and the DHI itself (technology, related distressing mental experiences, and main results). The spreadsheet was not modified during the examination of the selected articles.</p>
      </sec>
      <sec>
        <title>Analysis</title>
        <p>We conducted an inductive thematic content analysis using the reflexive approach by Braun and Clake [<xref ref-type="bibr" rid="ref22">22</xref>]. AD actively read the selected articles to obtain meaningful information and patterns in the data. He then constructed “codes” identifying the most basic and meaningful information regarding the attitudes of children, adolescents, and their parents toward DHIs. All the authors then collated these codes into categories according to their similarities; the categories were named and organized into themes showing a patterned response within the data set.</p>
      </sec>
    </sec>
    <sec sec-type="results">
      <title>Results</title>
      <sec>
        <title>General Information</title>
        <p>The 30 included articles originated from 10 countries and regions: the United States (n=13, 43%), the United Kingdom (n=3, 10%), Canada (n=3, 10%), Finland (n=2, 7%), the Netherlands (n=2, 7%), Australia (n=2, 7%), Sri Lanka (n=2, 7%), Austria (n=1, 3%), New Zealand (n=1, 3%), and the European Union (n=1, 3%). The articles were published between 2010 and 2021. The number of published articles increased over time, with a peak in 2019 (<xref ref-type="table" rid="table1">Table 1</xref>).</p>
        <table-wrap position="float" id="table1">
          <label>Table 1</label>
          <caption>
            <p>Number of articles according to year of publication (n=30).</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="500"/>
            <col width="500"/>
            <thead>
              <tr valign="top">
                <td>Year of publication</td>
                <td>Articles, n (%)</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td>2010</td>
                <td>2 (7)</td>
              </tr>
              <tr valign="top">
                <td>2011</td>
                <td>0 (0)</td>
              </tr>
              <tr valign="top">
                <td>2012</td>
                <td>1 (3)</td>
              </tr>
              <tr valign="top">
                <td>2013</td>
                <td>0 (0)</td>
              </tr>
              <tr valign="top">
                <td>2014</td>
                <td>2 (7)</td>
              </tr>
              <tr valign="top">
                <td>2015</td>
                <td>1 (3)</td>
              </tr>
              <tr valign="top">
                <td>2016</td>
                <td>3 (10)</td>
              </tr>
              <tr valign="top">
                <td>2017</td>
                <td>3 (10)</td>
              </tr>
              <tr valign="top">
                <td>2018</td>
                <td>4 (13)</td>
              </tr>
              <tr valign="top">
                <td>2019</td>
                <td>7 (23)</td>
              </tr>
              <tr valign="top">
                <td>2020</td>
                <td>6 (20)</td>
              </tr>
              <tr valign="top">
                <td>2021</td>
                <td>1 (3)</td>
              </tr>
            </tbody>
          </table>
        </table-wrap>
        <p>We identified 8 different ways to deliver DHIs, as mentioned by the authors of the articles included: videoconferencing (8/30, 27%), mobile apps (8/30, 27%), serious games (5/30, 17%), programs installed on a computer (1/30, 3%), electronic diaries (1/30, 3%), internet sites (2/30, 7%), mobile phones to take photos or videos (1/30, 3%), and virtual environments (1/30, 3%). However, 3 articles did not investigate a specific DHI delivery technology.</p>
        <p>Overall, 8 different types of therapy delivered through DHIs were identified: cognitive behavioral therapy (9/30, 30%), mental health and general health education (5/30, 17%), medical examinations (5/30, 17%), group therapy (1/30, 3%), contingency management (1/30, 3%), social skills (1/30, 3%), alternative and augmentative communication (1/30, 3%), and mood monitoring (1/30, 3%). However, 6 articles did not specify the type of therapy delivered by the DHI.</p>
        <p>The DHI discussed in various articles explored either a specific mental health problem or more general transdiagnostic symptoms. A total of 23 authors mentioned a single distressing mental experience: anxiety disorder (n=5, 17%; including anxiety in autism spectrum disorder [ASD] and social anxiety disorder), ASD (n=3, 10%), depressive disorder (n=2, 7%), substance use disorder (n=4, 13%), sleep behaviors (n=2, 7%), attention deficit with or without hyperactivity disorder (n=1, 3%), risk-taking behaviors (in terms of drugs and sexual activity; n=2, 7%), psychosis (n=1, 3%), nonsuicidal self-injury (n=1, 3%), and neurodevelopmental disorder (n=1, 3%). One article mentioned 3 distressing mental experiences (anxiety, depressive, and eating disorders), whereas another focused on mental health well-being in general. The remaining 6 articles did not mention any specific distressing mental experiences.</p>
        <p>We identified six different places or means of recruitment from the articles as follows: (1) nonuniversity care (15/30, 50%; including local structures and general nonuniversity hospitals, general practitioners, nonuniversity mental health clinics, and mental health consultations in a specialist center); (2) schools (8/30, 27%) where consultation services were provided in middle and high schools—one article mentioned a special school for children with specific needs regarding communication skills; (3) social services (4/30, 13%; school counselors, social counselors, or community counselors); (4) community activities (2/30, 7%); (5) public advertising (2/30, 7%; posters at community events, school conferences, local conferences, and street and social media advertising); and (6) university hospitals (3/30, 10%; inpatient and outpatient consultations). Some studies (6/30, 20%) included &#62;1 method of recruitment. One study did not indicate where the study population was recruited. Finally, the study population in one study was derived from users’ reviews published on a mobile app provider.</p>
        <p>Overall, 4 and 5 articles recruited study populations from rural areas and underprivileged communities, respectively. Furthermore, 2 of these 9 articles were recruited from both rural and underprivileged minority communities. Underprivileged communities included low-income populations and ethnic or colored minority populations.</p>
        <p>Of the 30 studies, 19 interviewed children and adolescents, whereas 7 interviewed children, adolescents, and their parents. Furthermore, 3 studies interviewed only parents. One study did not specify whether the data were from children, adolescents, or parents. Overall, 1891 children and adolescents were included in the study. As only 9 articles provided the mean age of the participants, we were unable to provide global statistics. Nevertheless, based on the inclusion criteria, we were able to identify different age groups: 13- to 18-year-old adolescents (22/30, 73%), 6- to 12-year-old children (9/30, 30%), 2- to 5-year-old preschool children (1/30, 3%), and 0- to 23-month-old infants (1/30, 3%). Furthermore, 7 studies included 2 different age groups.</p>
        <p>Of the 26 studies that interviewed children and adolescents, 4 did not provide data on gender or provided incomplete data. We counted a total of 397 (24%) boys and 1215 (66%) girls in the other 22 articles. It is important to highlight that one exploratory survey included 775 teenage girls.</p>
        <p>In total, 11 studies consulted parents on their attitudes toward the DHI used by their children and adolescents. Specifically, parents were consulted in 5 feasibility studies, 3 qualitative studies, 2 participative studies, and 1 survey. A total of 310 parents were included in this study. Only 5 studies included data on parents’ gender: among 73 parents, 60 were mothers and 13 were fathers.</p>
      </sec>
      <sec>
        <title>Themes of Articles</title>
        <p>We identified 5 themes in the 30 selected articles, as defined in <xref ref-type="boxed-text" rid="box1">Textbox 1</xref>. Each article provided data on 1 to 4 of these themes (<xref ref-type="table" rid="table2">Tables 2</xref>-<xref ref-type="table" rid="table6">6</xref>).</p>
        <p>The most frequent theme was <italic>Use</italic> that was found in 22 studies (<xref ref-type="table" rid="table5">Table 5</xref>) [<xref ref-type="bibr" rid="ref24">24</xref>,<xref ref-type="bibr" rid="ref28">28</xref>,<xref ref-type="bibr" rid="ref30">30</xref>-<xref ref-type="bibr" rid="ref37">37</xref>,<xref ref-type="bibr" rid="ref39">39</xref>-<xref ref-type="bibr" rid="ref43">43</xref>,<xref ref-type="bibr" rid="ref45">45</xref>,<xref ref-type="bibr" rid="ref47">47</xref>-<xref ref-type="bibr" rid="ref52">52</xref>]: 7 exploratory studies, 8 observational studies, 3 trials, 2 randomized controlled trials, and 2 participatory research studies. Data were collected through semistructured interviews, focus groups, and surveys. These data included attendance rate, completion of intervention rate, and use rates. <italic>Use</italic> was investigated with regard to the current use of ICT, current use of a DHI, accessibility of the DHI evaluated in the study, and intervention completion or attendance rates. Overall, adolescents reported a wide range of uses of ICT, including entertainment, information, and social communication. Some used the internet to obtain help about problems they encountered related to their mental well-being. ICT use revealed new opportunities for care, for example, the distribution of information about drug use rehabilitation through social media to better reach adolescents and counterbalance drug cues [<xref ref-type="bibr" rid="ref35">35</xref>]. With regard to current DHI use, an exploratory study found that 16.1% of adolescent girls with mental health problems already used a mobile app for support [<xref ref-type="bibr" rid="ref39">39</xref>]. When evaluating a DHI, adolescents judged the aesthetic dimension, whether it was easy to use, and whether it had customizable features.</p>
        <boxed-text id="box1" position="float">
          <title>Definitions of the 5 identified themes.</title>
          <list list-type="bullet">
            <list-item>
              <p>Satisfaction: This included measures of digital health intervention (DHI) satisfaction and acceptability as well as information on adherence to treatment.</p>
            </list-item>
            <list-item>
              <p>Use: This covered DHI intervention completion rates, attendance rates, comments about how easy or difficult the existing DHI was to use, and information on barriers or facilitators to use.</p>
            </list-item>
            <list-item>
              <p>Preferences: This regarded user preferences for different DHI treatment means and intervention features.</p>
            </list-item>
            <list-item>
              <p>Perception: This included information on the participant’s perception of the DHI used, his or her motivation to use it, and his or her perception of the DHI’s usefulness and credibility.</p>
            </list-item>
            <list-item>
              <p>Needs: This covered information on the features, content, and design of future DHIs.</p>
            </list-item>
          </list>
        </boxed-text>
        <table-wrap position="float" id="table2">
          <label>Table 2</label>
          <caption>
            <p>Characteristics of the reviewed articles (part 1).</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="150"/>
            <col width="130"/>
            <col width="90"/>
            <col width="190"/>
            <col width="190"/>
            <col width="150"/>
            <col width="100"/>
            <thead>
              <tr valign="top">
                <td>Author</td>
                <td>Country</td>
                <td>Year of publication</td>
                <td>Themes</td>
                <td>Method</td>
                <td>Population</td>
                <td>Parents</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td>Čuš et al [<xref ref-type="bibr" rid="ref23">23</xref>]</td>
                <td>Austria</td>
                <td>2021</td>
                <td>Needs, preference</td>
                <td>Exploratory, semistructured interviews</td>
                <td>Adolescents</td>
                <td>No</td>
              </tr>
              <tr valign="top">
                <td>Lopez et al [<xref ref-type="bibr" rid="ref24">24</xref>]</td>
                <td>United States</td>
                <td>2020</td>
                <td>Satisfaction, use, preference</td>
                <td>Observational, survey, semistructured interviews</td>
                <td>Adolescents</td>
                <td>No</td>
              </tr>
              <tr valign="top">
                <td>Mayworm et al [<xref ref-type="bibr" rid="ref25">25</xref>]</td>
                <td>United States</td>
                <td>2020</td>
                <td>Satisfaction, preference</td>
                <td>Observational, survey</td>
                <td>N/A<sup>a</sup></td>
                <td>Yes (n=125)</td>
              </tr>
              <tr valign="top">
                <td>Hettiarachchi et al [<xref ref-type="bibr" rid="ref26">26</xref>]</td>
                <td>Sri Lanka</td>
                <td>2020</td>
                <td>Perception</td>
                <td>Observational, semistructured interviews, focus groups</td>
                <td>N/A</td>
                <td>Yes (n=16)</td>
              </tr>
              <tr valign="top">
                <td>Widnall et al [<xref ref-type="bibr" rid="ref27">27</xref>]</td>
                <td>United Kingdom</td>
                <td>2020</td>
                <td>Perception, needs, preference</td>
                <td>Observational, focus groups</td>
                <td>N/A</td>
                <td>No</td>
              </tr>
              <tr valign="top">
                <td>Newton et al [<xref ref-type="bibr" rid="ref28">28</xref>]</td>
                <td>Canada</td>
                <td>2020</td>
                <td>Needs, preference, use, satisfaction</td>
                <td>Participatory research, surveys, semistructured interviews</td>
                <td>Adolescents</td>
                <td>No</td>
              </tr>
              <tr valign="top">
                <td>Terlouw et al [<xref ref-type="bibr" rid="ref29">29</xref>]</td>
                <td>The Netherland</td>
                <td>2020</td>
                <td>Needs, preference, perception</td>
                <td>Participatory research, focus groups, interviews</td>
                <td>Children</td>
                <td>Yes (n=6)</td>
              </tr>
              <tr valign="top">
                <td>Metsäranta et al [<xref ref-type="bibr" rid="ref30">30</xref>]</td>
                <td>Finland</td>
                <td>2019</td>
                <td>Use</td>
                <td>Trial, use rate, writes analysis</td>
                <td>Adolescents</td>
                <td>No</td>
              </tr>
              <tr valign="top">
                <td>Werner-Seidler et al [<xref ref-type="bibr" rid="ref31">31</xref>]</td>
                <td>Australia</td>
                <td>2019</td>
                <td>Satisfaction, use</td>
                <td>Trial, feasibility, survey, semistructured interviews</td>
                <td>Adolescents</td>
                <td>No</td>
              </tr>
              <tr valign="top">
                <td>Quante et al [<xref ref-type="bibr" rid="ref32">32</xref>]</td>
                <td>United States</td>
                <td>2019</td>
                <td>Needs, use, preference</td>
                <td>Observational, focus groups</td>
                <td>Adolescents</td>
                <td>No</td>
              </tr>
              <tr valign="top">
                <td>Gigantesco et al [<xref ref-type="bibr" rid="ref33">33</xref>]</td>
                <td>Europe</td>
                <td>2019</td>
                <td>Use, preference</td>
                <td>Exploratory, focus groups, semistructured interviews</td>
                <td>Children, adolescents</td>
                <td>No</td>
              </tr>
              <tr valign="top">
                <td>Bagot et al [<xref ref-type="bibr" rid="ref34">34</xref>]</td>
                <td>United States</td>
                <td>2019</td>
                <td>Use, needs</td>
                <td>Exploratory, focus groups</td>
                <td>Adolescents</td>
                <td>No</td>
              </tr>
              <tr valign="top">
                <td>Soysa et al [<xref ref-type="bibr" rid="ref31">31</xref>]</td>
                <td>Sri Lanka</td>
                <td>2019</td>
                <td>Perception, needs, use</td>
                <td>Exploratory, semistructured interviews, focus groups</td>
                <td>N/A</td>
                <td>Yes (n=32)</td>
              </tr>
              <tr valign="top">
                <td>Curtis et al [<xref ref-type="bibr" rid="ref35">35</xref>]</td>
                <td>United States</td>
                <td>2019</td>
                <td>Use, perceptions</td>
                <td>Exploratory, survey</td>
                <td>Adolescents</td>
                <td>No</td>
              </tr>
              <tr valign="top">
                <td>Juárez et al [<xref ref-type="bibr" rid="ref36">36</xref>]</td>
                <td>United States</td>
                <td>2018</td>
                <td>Use, satisfaction</td>
                <td>Observational, survey</td>
                <td>Toddlers, preschool children</td>
                <td>Yes (n=41)</td>
              </tr>
            </tbody>
          </table>
          <table-wrap-foot>
            <fn id="table2fn1">
              <p><sup>a</sup>N/A: not applicable.</p>
            </fn>
          </table-wrap-foot>
        </table-wrap>
        <table-wrap position="float" id="table3">
          <label>Table 3</label>
          <caption>
            <p>Characteristics of the reviewed articles (part 2).</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="150"/>
            <col width="130"/>
            <col width="90"/>
            <col width="190"/>
            <col width="190"/>
            <col width="150"/>
            <col width="100"/>
            <thead>
              <tr valign="top">
                <td>Author</td>
                <td>Country</td>
                <td>Year of publication</td>
                <td>Themes</td>
                <td>Method</td>
                <td>Population</td>
                <td>Parents</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td>Carpenter et al [<xref ref-type="bibr" rid="ref37">37</xref>]</td>
                <td>United States</td>
                <td>2018</td>
                <td>Use, satisfaction</td>
                <td>Observational, feasibility</td>
                <td>Children and adolescents</td>
                <td>Yes (n=11)</td>
              </tr>
              <tr valign="top">
                <td>Clark et al [<xref ref-type="bibr" rid="ref38">38</xref>]</td>
                <td>Australia</td>
                <td>2018</td>
                <td>Perception, preference</td>
                <td>Exploratory, semistructured interviews, focus groups</td>
                <td>Adolescents</td>
                <td>No</td>
              </tr>
              <tr valign="top">
                <td>Grist et al [<xref ref-type="bibr" rid="ref39">39</xref>]</td>
                <td>United Kingdom</td>
                <td>2018</td>
                <td>Perception, use, preference</td>
                <td>Exploratory, survey</td>
                <td>Adolescents</td>
                <td>No</td>
              </tr>
              <tr valign="top">
                <td>Kong et al [<xref ref-type="bibr" rid="ref40">40</xref>]</td>
                <td>United States</td>
                <td>2017</td>
                <td>Use, satisfaction</td>
                <td>Trial, feasibility, survey</td>
                <td>Adolescents</td>
                <td>No</td>
              </tr>
              <tr valign="top">
                <td>Roberts et al [<xref ref-type="bibr" rid="ref41">41</xref>]</td>
                <td>Canada</td>
                <td>2017</td>
                <td>Satisfaction, use</td>
                <td>Observational, survey</td>
                <td>Adolescents</td>
                <td>No</td>
              </tr>
              <tr valign="top">
                <td>Hepburn et al [<xref ref-type="bibr" rid="ref42">42</xref>]</td>
                <td>United States</td>
                <td>2016</td>
                <td>Satisfaction, use</td>
                <td>RCT<sup>a</sup>, feasibility, survey</td>
                <td>Children and adolescents</td>
                <td>Yes (n=17)</td>
              </tr>
              <tr valign="top">
                <td>Pendergrass et al [<xref ref-type="bibr" rid="ref43">43</xref>]</td>
                <td>United States</td>
                <td>2016</td>
                <td>Perception, preference, use</td>
                <td>Observational, semistructured interviews</td>
                <td>Adolescents</td>
                <td>Yes (n=8)</td>
              </tr>
              <tr valign="top">
                <td>Sockolow et al [<xref ref-type="bibr" rid="ref44">44</xref>]</td>
                <td>United States</td>
                <td>2017</td>
                <td>Needs, preference</td>
                <td>Participatory research, focus groups</td>
                <td>Adolescents</td>
                <td>No</td>
              </tr>
              <tr valign="top">
                <td>Laine et al [<xref ref-type="bibr" rid="ref45">45</xref>]</td>
                <td>Finland</td>
                <td>2016</td>
                <td>Needs, use</td>
                <td>Participatory research, interviews</td>
                <td>Adolescents</td>
                <td>Yes (n=12)</td>
              </tr>
              <tr valign="top">
                <td>Bul et al [<xref ref-type="bibr" rid="ref46">46</xref>]</td>
                <td>Netherlands</td>
                <td>2015</td>
                <td>Perception, needs, satisfaction</td>
                <td>Observational, survey</td>
                <td>Children</td>
                <td>No</td>
              </tr>
              <tr valign="top">
                <td>Stasiak et al [<xref ref-type="bibr" rid="ref47">47</xref>]</td>
                <td>New Zealand</td>
                <td>2014</td>
                <td>Satisfaction, use</td>
                <td>RCT, feasibility, survey, semistructured interviews</td>
                <td>Adolescents</td>
                <td>No</td>
              </tr>
              <tr valign="top">
                <td>Sarver et al [<xref ref-type="bibr" rid="ref48">48</xref>]</td>
                <td>United States</td>
                <td>2014</td>
                <td>Satisfaction, use</td>
                <td>Observational, feasibility, attendance use, survey</td>
                <td>Children</td>
                <td>No</td>
              </tr>
              <tr valign="top">
                <td>Jacob et al [<xref ref-type="bibr" rid="ref49">49</xref>]</td>
                <td>United States</td>
                <td>2012</td>
                <td>Use, satisfaction</td>
                <td>Observational, feasibility, survey</td>
                <td>Children and adolescents</td>
                <td>Yes (n=11)</td>
              </tr>
              <tr valign="top">
                <td>Boydell et al [<xref ref-type="bibr" rid="ref50">50</xref>]</td>
                <td>Canada</td>
                <td>2010</td>
                <td>Perception, preference, use</td>
                <td>Observational, semistructured interviews</td>
                <td>Children and adolescents</td>
                <td>No</td>
              </tr>
              <tr valign="top">
                <td>Stallard et al [<xref ref-type="bibr" rid="ref51">51</xref>]</td>
                <td>England</td>
                <td>2010</td>
                <td>Use perceptions preferences</td>
                <td>Exploratory, survey</td>
                <td>Children and adolescents</td>
                <td>Yes (n=31)</td>
              </tr>
            </tbody>
          </table>
          <table-wrap-foot>
            <fn id="table3fn1">
              <p><sup>a</sup>RCT: randomized controlled trial.</p>
            </fn>
          </table-wrap-foot>
        </table-wrap>
        <table-wrap position="float" id="table4">
          <label>Table 4</label>
          <caption>
            <p>Results of the reviewed articles (part 1).</p>
          </caption>
          <table border="1" rules="groups" cellpadding="5" frame="hsides" width="1000" cellspacing="0">
            <col width="150"/>
            <col width="160"/>
            <col width="170"/>
            <col width="150"/>
            <col width="370"/>
            <thead>
              <tr valign="top">
                <td>Article</td>
                <td>Technology</td>
                <td>Distressing mental experience</td>
                <td>Therapy</td>
                <td>Results</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td>Čuš et al [<xref ref-type="bibr" rid="ref23">23</xref>], 2021</td>
                <td>Mobile app</td>
                <td>NSSI<sup>a</sup></td>
                <td>CBT<sup>b</sup></td>
                <td>The intervention should offer specific features regarding NSSI; it should be customizable and suitable for adolescents.</td>
              </tr>
              <tr valign="top">
                <td>Lopez et al [<xref ref-type="bibr" rid="ref24">24</xref>], 2020</td>
                <td>Videoconference</td>
                <td>SUD<sup>c</sup></td>
                <td>Psycho or health education</td>
                <td>Users were satisfied and the program was usable. Strength was mobility and social connection.</td>
              </tr>
              <tr valign="top">
                <td>Mayworm et al [<xref ref-type="bibr" rid="ref25">25</xref>], 2020</td>
                <td>Videoconference</td>
                <td>Not specified</td>
                <td>Medical examination</td>
                <td>Parents’ and users’ satisfaction was high. No difference of satisfaction between videoconference and in-person setting.</td>
              </tr>
              <tr valign="top">
                <td>Hettiarachchi et al [<xref ref-type="bibr" rid="ref26">26</xref>], 2020</td>
                <td>Mobile app</td>
                <td>Neurodevelopmental disorder</td>
                <td>Augmentative and alternative communication</td>
                <td>Digital interventions were perceived as mainstream technologies, accessible, as a learning tool, and challenging stigma, and concerns were raised regarding cost.</td>
              </tr>
              <tr valign="top">
                <td>Widnall et al [<xref ref-type="bibr" rid="ref27">27</xref>], 2020</td>
                <td>Mobile app</td>
                <td>Not specified</td>
                <td>Mood monitoring</td>
                <td>8 major themes: accessibility, flexibility, representation of mood, users' request, reflecting on mood, technical features, design, and health promotion.</td>
              </tr>
              <tr valign="top">
                <td>Newton et al [<xref ref-type="bibr" rid="ref28">28</xref>], 2020</td>
                <td>Mobile app</td>
                <td>Anxiety disorder</td>
                <td>CBT</td>
                <td>App should fit users’ needs and preferences, be easy to use, have relevant contents, and be aesthetic. Users’ satisfaction was high.</td>
              </tr>
              <tr valign="top">
                <td>Terlouw et al [<xref ref-type="bibr" rid="ref29">29</xref>], 2020</td>
                <td>Serious game</td>
                <td>ASD<sup>d</sup></td>
                <td>Social skills</td>
                <td>Children’s perceptions were around 3 main topics: everyday life, social skill training, and video games. Participants helped the creation of 3 personas. Children with ASD had different goals than their parents and professionals.</td>
              </tr>
              <tr valign="top">
                <td>Metsäranta et al [<xref ref-type="bibr" rid="ref30">30</xref>], 2019</td>
                <td>Electronic diary</td>
                <td>Depressive disorder</td>
                <td>Not specified</td>
                <td>Half did not use the e-diary. Adolescents used it to describe their symptoms, relationships, and identity.</td>
              </tr>
              <tr valign="top">
                <td>Werner-Seidler et al [<xref ref-type="bibr" rid="ref31">31</xref>], 2019</td>
                <td>Mobile app</td>
                <td>Sleep behavior</td>
                <td>CBT</td>
                <td>Users were satisfied and the intervention was feasible. Users recommended several improvements. Reasons for nonadherence were documented.</td>
              </tr>
              <tr valign="top">
                <td>Quante et al [<xref ref-type="bibr" rid="ref32">32</xref>], 2019</td>
                <td>Mobile app</td>
                <td>Sleep behavior</td>
                <td>Not specified</td>
                <td>Adolescents were reluctant to change behavior but were open to counseling. They suggested improvement on usability and customization.</td>
              </tr>
              <tr valign="top">
                <td>Gigantesco et al [<xref ref-type="bibr" rid="ref33">33</xref>], 2019</td>
                <td>Not specified</td>
                <td>Mental health well-being</td>
                <td>Psycho or health education</td>
                <td>The majority preferred smartphones to communicate and used tablets at school. Collaborative games were considered more useful.</td>
              </tr>
              <tr valign="top">
                <td>Bagot et al [<xref ref-type="bibr" rid="ref34">34</xref>], 2019</td>
                <td>Mobile app</td>
                <td>SUD</td>
                <td>Not specified</td>
                <td>Themes were youth value rewards to reduce use, self-monitored progression, peer social support, privacy, and customization.</td>
              </tr>
              <tr valign="top">
                <td>Soysa et al [<xref ref-type="bibr" rid="ref31">31</xref>], 2019</td>
                <td>Not specified</td>
                <td>ASD</td>
                <td>Not specified</td>
                <td>Parents mostly used passive learning technologies. Technologies were used to teach academic skills. Future applications should fit Sri Lanka culture and be customizable.</td>
              </tr>
              <tr valign="top">
                <td>Curtis et al [<xref ref-type="bibr" rid="ref35">35</xref>], 2019</td>
                <td>Not specified</td>
                <td>SUD</td>
                <td>Not specified</td>
                <td>53 adolescents and 111 young adults completed the survey. Adolescents used the features of social media more. Many were exposed to drug cues on social media, whereas fewer observed recovery information. They felt that social media, smartphone apps, texting, or websites would be useful in delivering support.</td>
              </tr>
              <tr valign="top">
                <td>Juárez et al [<xref ref-type="bibr" rid="ref36">36</xref>], 2018</td>
                <td>Videoconference</td>
                <td>ASD</td>
                <td>Medical examination</td>
                <td>High satisfaction. Use showed that intervention saved time.</td>
              </tr>
            </tbody>
          </table>
          <table-wrap-foot>
            <fn id="table4fn1">
              <p><sup>a</sup>NSSI: Nonsuicidal self-injury.</p>
            </fn>
            <fn id="table4fn2">
              <p><sup>b</sup>CBT: cognitive behavioral therapy.</p>
            </fn>
            <fn id="table4fn3">
              <p><sup>c</sup>SUD: substance use disorder.</p>
            </fn>
            <fn id="table4fn4">
              <p><sup>d</sup>ASD: autism spectrum disorder.</p>
            </fn>
          </table-wrap-foot>
        </table-wrap>
        <table-wrap position="float" id="table5">
          <label>Table 5</label>
          <caption>
            <p>Results of the reviewed articles (part 2).</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="150"/>
            <col width="160"/>
            <col width="170"/>
            <col width="150"/>
            <col width="370"/>
            <thead>
              <tr valign="top">
                <td>Author</td>
                <td>Technology</td>
                <td>Distressing mental experience</td>
                <td>Therapy</td>
                <td>Results</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td>Carpenter et al [<xref ref-type="bibr" rid="ref37">37</xref>], 2018</td>
                <td>Videoconference</td>
                <td>Anxiety disorder</td>
                <td>CBT<sup>a</sup></td>
                <td>Intervention was feasible and acceptable. Results include barriers to care.</td>
              </tr>
              <tr valign="top">
                <td>Clark et al [<xref ref-type="bibr" rid="ref38">38</xref>], 2018</td>
                <td>Internet site</td>
                <td>Anxiety disorder</td>
                <td>CBT</td>
                <td>Major themes were “risks,” “efforts,” and “need for human connection.”</td>
              </tr>
              <tr valign="top">
                <td>Grist et al [<xref ref-type="bibr" rid="ref39">39</xref>], 2018</td>
                <td>Mobile app</td>
                <td>Anxiety, depressive, and eating disorder</td>
                <td>Not specified</td>
                <td>775 responses were gathered. 98.7% and 97.4% used the internet and apps. Only 6% used mental health mobile apps. Within those with symptoms, 15% to 17% used mental health apps. Young female adolescents massively used the internet and apps but not for mental health purposes.</td>
              </tr>
              <tr valign="top">
                <td>Kong et al [<xref ref-type="bibr" rid="ref40">40</xref>], 2017</td>
                <td>Mobile phone to take photos or videos</td>
                <td>SUD<sup>b</sup></td>
                <td>Contingency management</td>
                <td>Intervention was feasible and acceptable. Use could be difficult.</td>
              </tr>
              <tr valign="top">
                <td>Roberts et al [<xref ref-type="bibr" rid="ref41">41</xref>], 2017</td>
                <td>Videoconference</td>
                <td>Not specified</td>
                <td>Medical examination</td>
                <td>High satisfaction with the use of telepsychiatry. The service was thought to be user-friendly and to help save time and money</td>
              </tr>
              <tr valign="top">
                <td>Hepburn et al [<xref ref-type="bibr" rid="ref42">42</xref>], 2016</td>
                <td>Videoconference</td>
                <td>Anxiety disorder in ASD<sup>c</sup></td>
                <td>Group therapy</td>
                <td>Parents’ and users’ satisfaction was high. Intervention was feasible and acceptable. Users made suggestions for improvement.</td>
              </tr>
              <tr valign="top">
                <td>Pendergrass et al [<xref ref-type="bibr" rid="ref43">43</xref>], 2016</td>
                <td>Serious game</td>
                <td>Risk-taking behavior</td>
                <td>Psycho or health education</td>
                <td>4 themes were identified: teaching about sex, alcohol, and drugs was not done at school; a video game was a viable option; it would fit in several settings; and addition tools could be useful.</td>
              </tr>
              <tr valign="top">
                <td>Sockolow et al [<xref ref-type="bibr" rid="ref44">44</xref>], 2017</td>
                <td>Serious game</td>
                <td>Risk-taking behavior</td>
                <td>Psycho or health education</td>
                <td>Participants helped develop the story, reflecting their needs. Need-elicitation reflected the patient-centered care approach. Game fitted adolescents.</td>
              </tr>
              <tr valign="top">
                <td>Laine et al [<xref ref-type="bibr" rid="ref45">45</xref>], 2016</td>
                <td>Internet site</td>
                <td>Psychosis</td>
                <td>Psycho or health education</td>
                <td>Adolescents’ and professionals’ needs were related to the contents, usability, and design. Program was modified to satisfy adolescents’ needs.</td>
              </tr>
              <tr valign="top">
                <td>Bul et al [<xref ref-type="bibr" rid="ref46">46</xref>], 2015</td>
                <td>Serious game</td>
                <td>ADHD<sup>d</sup></td>
                <td>CBT</td>
                <td>Game development and scientific background behind the game are described. Users were satisfied and provided reviews for further development.</td>
              </tr>
              <tr valign="top">
                <td>Stasiak et al [<xref ref-type="bibr" rid="ref47">47</xref>], 2014</td>
                <td>Serious game</td>
                <td>Depressive disorder</td>
                <td>CBT</td>
                <td>Intervention was feasible and acceptable. Strengths were mobility, usefulness, and that it fitted adolescents. Weakness was use difficulties.</td>
              </tr>
              <tr valign="top">
                <td>Sarver et al [<xref ref-type="bibr" rid="ref48">48</xref>], 2014</td>
                <td>Virtual environments</td>
                <td>Social anxiety disorder</td>
                <td>CBT</td>
                <td>Intervention was feasible, acceptable, and credible.</td>
              </tr>
              <tr valign="top">
                <td>Jacob et al [<xref ref-type="bibr" rid="ref49">49</xref>], 2012</td>
                <td>Videoconference</td>
                <td>Not specified</td>
                <td>Medical examination</td>
                <td>High satisfaction from parents. Telepsychiatry was thought to offer a benefit in the ability to offer medical services in underserved area.</td>
              </tr>
              <tr valign="top">
                <td>Boydell et al [<xref ref-type="bibr" rid="ref50">50</xref>], 2010</td>
                <td>Videoconference</td>
                <td>Not specified</td>
                <td>Medical examination</td>
                <td>4 themes arose: the encounter with the psychiatrist, the helpfulness, a sense of choice, and technology.</td>
              </tr>
              <tr valign="top">
                <td>Stallard et al [<xref ref-type="bibr" rid="ref51">51</xref>], 2010</td>
                <td>Computer</td>
                <td>Not specified</td>
                <td>CBT</td>
                <td>68 responses (37 young people and 31 parents) were gathered. Young people reported high level of computer use and web-based–seeking behavior. Parents were positive about computerized therapy, whereas young people expressed caution.</td>
              </tr>
            </tbody>
          </table>
        </table-wrap>
        <table-wrap position="float" id="table6">
          <label>Table 6</label>
          <caption>
            <p>Themes explored in the reviewed articles.</p>
          </caption>
          <table border="1" rules="groups" cellpadding="5" frame="hsides" width="1000" cellspacing="0">
            <col width="120"/>
            <col width="180"/>
            <col width="90"/>
            <col width="170"/>
            <col width="200"/>
            <col width="240"/>
            <thead>
              <tr valign="top">
                <td>Themes</td>
                <td>References</td>
                <td>Sample, N</td>
                <td>Population</td>
                <td>Technologies</td>
                <td>Distressing mental experiences</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td>Use</td>
                <td>[<xref ref-type="bibr" rid="ref15">15</xref>-<xref ref-type="bibr" rid="ref22">22</xref>,<xref ref-type="bibr" rid="ref24">24</xref>,<xref ref-type="bibr" rid="ref28">28</xref>, <xref ref-type="bibr" rid="ref30">30</xref>-<xref ref-type="bibr" rid="ref32">32</xref>,<xref ref-type="bibr" rid="ref34">34</xref>, <xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref37">37</xref>,<xref ref-type="bibr" rid="ref40">40</xref>, <xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref45">45</xref>,<xref ref-type="bibr" rid="ref47">47</xref>,<xref ref-type="bibr" rid="ref48">48</xref>, <xref ref-type="bibr" rid="ref52">52</xref>]</td>
                <td>22</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Toddler</p>
                    </list-item>
                    <list-item>
                      <p>Child</p>
                    </list-item>
                    <list-item>
                      <p>Adolescent</p>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Computer</p>
                    </list-item>
                    <list-item>
                      <p>Electronic diary</p>
                    </list-item>
                    <list-item>
                      <p>Internet site</p>
                    </list-item>
                    <list-item>
                      <p>Mobile app</p>
                    </list-item>
                    <list-item>
                      <p>Mobile phone (photo)</p>
                    </list-item>
                    <list-item>
                      <p>Serious game</p>
                    </list-item>
                    <list-item>
                      <p>Videoconference</p>
                    </list-item>
                    <list-item>
                      <p>Virtual environment</p>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Anxiety disorder in ASD<sup>a</sup></p>
                    </list-item>
                    <list-item>
                      <p>Anxiety disorder</p>
                    </list-item>
                    <list-item>
                      <p>Depressive disorder</p>
                    </list-item>
                    <list-item>
                      <p>Eating disorder</p>
                    </list-item>
                    <list-item>
                      <p>ASD</p>
                    </list-item>
                    <list-item>
                      <p>Mental health well-being</p>
                    </list-item>
                    <list-item>
                      <p>Psychosis</p>
                    </list-item>
                    <list-item>
                      <p>Risk-taking behavior</p>
                    </list-item>
                    <list-item>
                      <p>Sleep behavior</p>
                    </list-item>
                    <list-item>
                      <p>Social anxiety disorder</p>
                    </list-item>
                    <list-item>
                      <p>SUD<sup>b</sup></p>
                    </list-item>
                  </list>
                </td>
              </tr>
              <tr valign="top">
                <td>Preferences</td>
                <td>[<xref ref-type="bibr" rid="ref15">15</xref>,<xref ref-type="bibr" rid="ref16">16</xref>,<xref ref-type="bibr" rid="ref20">20</xref>,<xref ref-type="bibr" rid="ref33">33</xref>,<xref ref-type="bibr" rid="ref35">35</xref>,<xref ref-type="bibr" rid="ref37">37</xref>, <xref ref-type="bibr" rid="ref39">39</xref>-<xref ref-type="bibr" rid="ref43">43</xref>, <xref ref-type="bibr" rid="ref50">50</xref>-<xref ref-type="bibr" rid="ref52">52</xref>]</td>
                <td>14</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Child</p>
                    </list-item>
                    <list-item>
                      <p>Adolescent</p>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Mobile app</p>
                    </list-item>
                    <list-item>
                      <p>Internet site</p>
                    </list-item>
                    <list-item>
                      <p>Mobile app</p>
                    </list-item>
                    <list-item>
                      <p>Serious game</p>
                    </list-item>
                    <list-item>
                      <p>Videoconference</p>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>NSSI<sup>c</sup></p>
                    </list-item>
                    <list-item>
                      <p>ADHD<sup>d</sup></p>
                    </list-item>
                    <list-item>
                      <p>Anxiety disorder</p>
                    </list-item>
                    <list-item>
                      <p>Depressive disorder</p>
                    </list-item>
                    <list-item>
                      <p>Eating disorder</p>
                    </list-item>
                    <list-item>
                      <p>ASD</p>
                    </list-item>
                    <list-item>
                      <p>Risk-taking behavior</p>
                    </list-item>
                    <list-item>
                      <p>Mental health well-being</p>
                    </list-item>
                  </list>
                </td>
              </tr>
              <tr valign="top">
                <td>Satisfaction</td>
                <td>[<xref ref-type="bibr" rid="ref15">15</xref>,<xref ref-type="bibr" rid="ref20">20</xref>-<xref ref-type="bibr" rid="ref22">22</xref>,<xref ref-type="bibr" rid="ref28">28</xref>,<xref ref-type="bibr" rid="ref30">30</xref>-<xref ref-type="bibr" rid="ref35">35</xref>,<xref ref-type="bibr" rid="ref45">45</xref>, <xref ref-type="bibr" rid="ref48">48</xref>]</td>
                <td>13</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Toddler</p>
                    </list-item>
                    <list-item>
                      <p>Child</p>
                    </list-item>
                    <list-item>
                      <p>Adolescent</p>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Mobile app</p>
                    </list-item>
                    <list-item>
                      <p>Mobile phone (photo)</p>
                    </list-item>
                    <list-item>
                      <p>Serious game</p>
                    </list-item>
                    <list-item>
                      <p>Videoconference</p>
                    </list-item>
                    <list-item>
                      <p>Virtual environment</p>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>ADHD</p>
                    </list-item>
                    <list-item>
                      <p>Anxiety disorder in ASD</p>
                    </list-item>
                    <list-item>
                      <p>Anxiety disorder</p>
                    </list-item>
                    <list-item>
                      <p>ASD</p>
                    </list-item>
                    <list-item>
                      <p>Depressive disorder</p>
                    </list-item>
                    <list-item>
                      <p>Sleep behavior</p>
                    </list-item>
                    <list-item>
                      <p>Social anxiety disorder</p>
                    </list-item>
                    <list-item>
                      <p>SUD</p>
                    </list-item>
                  </list>
                </td>
              </tr>
              <tr valign="top">
                <td>Perceptions</td>
                <td>[<xref ref-type="bibr" rid="ref18">18</xref>,<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref37">37</xref>,<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref43">43</xref>,<xref ref-type="bibr" rid="ref47">47</xref>, <xref ref-type="bibr" rid="ref49">49</xref>-<xref ref-type="bibr" rid="ref51">51</xref>]</td>
                <td>11</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Child Adolescent</p>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Computer</p>
                    </list-item>
                    <list-item>
                      <p>Internet site</p>
                    </list-item>
                    <list-item>
                      <p>Virtual environment</p>
                    </list-item>
                    <list-item>
                      <p>Mobile app</p>
                    </list-item>
                    <list-item>
                      <p>Serious game</p>
                    </list-item>
                    <list-item>
                      <p>Videoconference</p>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>ADHD</p>
                    </list-item>
                    <list-item>
                      <p>Anxiety disorder</p>
                    </list-item>
                    <list-item>
                      <p>Depressive disorder</p>
                    </list-item>
                    <list-item>
                      <p>Eating disorder</p>
                    </list-item>
                    <list-item>
                      <p>ASD</p>
                    </list-item>
                    <list-item>
                      <p>Neurodevelopmental disorder</p>
                    </list-item>
                    <list-item>
                      <p>Risk-taking behavior</p>
                    </list-item>
                    <list-item>
                      <p>Social anxiety disorder</p>
                    </list-item>
                    <list-item>
                      <p>SUD</p>
                    </list-item>
                  </list>
                </td>
              </tr>
              <tr valign="top">
                <td>Needs</td>
                <td>[<xref ref-type="bibr" rid="ref15">15</xref>-<xref ref-type="bibr" rid="ref19">19</xref>,<xref ref-type="bibr" rid="ref35">35</xref>,<xref ref-type="bibr" rid="ref39">39</xref>, <xref ref-type="bibr" rid="ref41">41</xref>,<xref ref-type="bibr" rid="ref43">43</xref>, <xref ref-type="bibr" rid="ref50">50</xref>]</td>
                <td>10</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Child Adolescent</p>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Mobile app</p>
                    </list-item>
                    <list-item>
                      <p>Internet site</p>
                    </list-item>
                    <list-item>
                      <p>Serious game</p>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>NSSI</p>
                    </list-item>
                    <list-item>
                      <p>Anxiety disorder</p>
                    </list-item>
                    <list-item>
                      <p>ASD</p>
                    </list-item>
                    <list-item>
                      <p>Psychosis</p>
                    </list-item>
                    <list-item>
                      <p>Risk-taking behavior</p>
                    </list-item>
                    <list-item>
                      <p>Sleep behavior</p>
                    </list-item>
                    <list-item>
                      <p>SUD</p>
                    </list-item>
                  </list>
                </td>
              </tr>
            </tbody>
          </table>
          <table-wrap-foot>
            <fn id="table6fn1">
              <p><sup>a</sup>ASD: autism spectrum disorder.</p>
            </fn>
            <fn id="table6fn2">
              <p><sup>b</sup>SUD: substance use disorder.</p>
            </fn>
            <fn id="table6fn3">
              <p><sup>c</sup>NSSI: nonsuicidal self-injury.</p>
            </fn>
            <fn id="table6fn4">
              <p><sup>d</sup>ADHD: attention-deficit/hyperactivity disorder.</p>
            </fn>
          </table-wrap-foot>
        </table-wrap>
        <p>Information on DHI user <italic>Preferences</italic> was found in 14 studies [<xref ref-type="bibr" rid="ref23">23</xref>-<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref27">27</xref>-<xref ref-type="bibr" rid="ref29">29</xref>,<xref ref-type="bibr" rid="ref32">32</xref>,<xref ref-type="bibr" rid="ref33">33</xref>,<xref ref-type="bibr" rid="ref38">38</xref>,<xref ref-type="bibr" rid="ref39">39</xref>,<xref ref-type="bibr" rid="ref43">43</xref>,<xref ref-type="bibr" rid="ref44">44</xref>,<xref ref-type="bibr" rid="ref46">46</xref>,<xref ref-type="bibr" rid="ref50">50</xref>], specifically, 6 observational studies, 5 exploratory studies, and 3 participatory studies. Data were collected through focus groups, semistructured interviews, and surveys. Information about preferences in the results contained 2 distinct concepts. Specifically, in 8 articles, adolescents and children stated their preferences for the intervention’s or the technology’s features. In the other 6 studies, the information collected regarded user preferences for the mode of care administration: in person or via DHI. Furthermore, 3 studies found that adolescents preferred DHIs over the in-person approach, as they helped avoid possible stigma related to mental health care and reduced anxiety through teleconferencing with a psychiatrist [<xref ref-type="bibr" rid="ref38">38</xref>,<xref ref-type="bibr" rid="ref43">43</xref>,<xref ref-type="bibr" rid="ref50">50</xref>]. Another 3 studies found that adolescents preferred the in-person setting to a DHI [<xref ref-type="bibr" rid="ref24">24</xref>,<xref ref-type="bibr" rid="ref39">39</xref>,<xref ref-type="bibr" rid="ref51">51</xref>].</p>
        <p>The <italic>Satisfaction</italic> theme appeared in 13 studies, specifically, 8 exploratory studies, 2 trials, 2 randomized controlled trials, and 1 participatory research study [<xref ref-type="bibr" rid="ref24">24</xref>,<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref28">28</xref>,<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref37">37</xref>,<xref ref-type="bibr" rid="ref40">40</xref>-<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref46">46</xref>-<xref ref-type="bibr" rid="ref49">49</xref>,<xref ref-type="bibr" rid="ref52">52</xref>]. Data on satisfaction were gathered using surveys and semistructured interviews. Using Likert-scale measurements, the authors asked users or their parents whether they were satisfied with the DHI, whether they would recommend it to their friends, or whether they would use it in the future.</p>
        <p>Information about <italic>Perception</italic> was found in 11 studies [<xref ref-type="bibr" rid="ref26">26</xref>,<xref ref-type="bibr" rid="ref27">27</xref>,<xref ref-type="bibr" rid="ref29">29</xref>,<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref35">35</xref>,<xref ref-type="bibr" rid="ref38">38</xref>,<xref ref-type="bibr" rid="ref39">39</xref>,<xref ref-type="bibr" rid="ref43">43</xref>,<xref ref-type="bibr" rid="ref50">50</xref>,<xref ref-type="bibr" rid="ref51">51</xref>], specifically, 5 observational studies, 5 exploratory studies, and 1 participatory research study. Data were gathered through surveys, semistructured interviews, and focus groups. The authors measured adolescents’ and their parents’ perception of the DHI, their eagerness to use it, and their curiosity and concerns about using it. With regard to their motivation to use the DHI, some adolescents said that effort was required just as effort was required with the in-person treatment approach [<xref ref-type="bibr" rid="ref38">38</xref>]. Others said that they were concerned about the security of the DHI that they used [<xref ref-type="bibr" rid="ref34">34</xref>,<xref ref-type="bibr" rid="ref38">38</xref>,<xref ref-type="bibr" rid="ref39">39</xref>].</p>
        <p>The least frequent theme was <italic>Needs</italic>, which only appeared in 10 studies [<xref ref-type="bibr" rid="ref23">23</xref>,<xref ref-type="bibr" rid="ref27">27</xref>-<xref ref-type="bibr" rid="ref29">29</xref>,<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref32">32</xref>,<xref ref-type="bibr" rid="ref34">34</xref>,<xref ref-type="bibr" rid="ref44">44</xref>-<xref ref-type="bibr" rid="ref46">46</xref>], specifically 3 exploratory studies, 3 observational studies, and 4 participatory studies. Data were gathered through surveys, focus groups, and semistructured interviews. In participatory studies, elicitation of users’ needs could happen early in the DHI design process and help define the objectives of the future intervention. In one study, where professionals were also interviewed, it was found that children with ASD wanted a serious game that could help them connect with their peers, whereas professionals were more focused on social skills [<xref ref-type="bibr" rid="ref29">29</xref>]. In general, adolescents and children expressed that DHIs should be customizable, facilitate social connection, be aesthetically pleasing, and be easy to use. These elements mirror their feedback on <italic>Use</italic>.</p>
      </sec>
    </sec>
    <sec sec-type="discussion">
      <title>Discussion</title>
      <sec>
        <title>Principal Findings</title>
        <p>We conducted a rigorous scoping review exploring children’s, adolescents’, and parents’ attitudes toward DHI. We mapped and identified relevant studies, provided information on how research has been conducted to date, and presented preliminary results. After a thorough literature review, of the 1548 studies identified, 30 (1.94%) were analyzed. We extracted information related to the publication of the study, its methodology, the population concerned, and the DHI explored. We then identified 5 themes that emerged in the studies: satisfaction, use, preferences, perception, and needs.</p>
      </sec>
      <sec>
        <title>Population, Recruitment, and Countries of Origin</title>
        <p>A total of 4 age groups were identified in our sample; adolescents were by far the most interviewed group. This is consistent with the fact that children and adolescents have more access to the internet and spend more time on the web as they grow and are therefore more concerned with ICT and DHI [<xref ref-type="bibr" rid="ref6">6</xref>]. The attitudes of preschool children and infants were investigated very little, with only one study focusing on these age groups [<xref ref-type="bibr" rid="ref36">36</xref>]. This result can be explained by the fact that there are very few DHIs designed for very young age groups [<xref ref-type="bibr" rid="ref53">53</xref>]. For example, a scoping review published in 2019 on DHI and mental health literacy for the children aged 2 to 12 years children found only 4 results [<xref ref-type="bibr" rid="ref53">53</xref>]. To the best of our knowledge, no previous review has explored the engagement of families of toddlers and preschool children in DHIs.</p>
        <p>Our review focused on child and adolescent mental health service users, and therefore may have missed nonclinical users, who most probably constitute a nonnegligible part of the general population. However, the articles we analyzed came from clinical and nonclinical populations and included both DHI-naive and DHI-experienced users. It is possible that if we had not specified “mental health service users” in the search, we may have found more studies.</p>
        <p>The wide range of study recruitment techniques described in the studies reflects the diversity of DHI uses and the services these interventions offer. This underlines the importance of the DHIs in various dimensions of care, including prevention, facilitating help-seeking behavior, self-help, and complementing face-to-face services.</p>
        <p>Of the 30 studies, 7 (23%) specifically mentioned rural areas or underprivileged minority populations. One of the main advantages of DHIs is that they provide care to these underserved populations owing to the fact that they are accessible and cost-effective [<xref ref-type="bibr" rid="ref7">7</xref>,<xref ref-type="bibr" rid="ref54">54</xref>]. Only one study was conducted in a non-Western country. This underlines the insufficient research in this area in non-Western settings. It also shows a lack of DHI access in low- and middle-income countries [<xref ref-type="bibr" rid="ref7">7</xref>,<xref ref-type="bibr" rid="ref55">55</xref>]. This may be because of the limited resources, a shortage of skilled personnel, poor internet connectivity, and a lack of mental health policies for children and adolescents [<xref ref-type="bibr" rid="ref7">7</xref>].</p>
      </sec>
      <sec>
        <title>Attitudes to DHI During the COVID-19 Pandemic</title>
        <p>The COVID-19 pandemic crisis is seen as a pivotal point in the use of digital health in mental health. This highlights the key role that digital tools can play in terms of care when face-to-face visits are impossible [<xref ref-type="bibr" rid="ref56">56</xref>]. However, we found no study matching our inclusion criteria that specifically explored children’s and adolescents’ attitudes toward DHIs during the COVID-19 crisis. It must be said that the time frame covered in our review (January 1, 2007, to July 8, 2021) limited the possibility to identify such articles. Some articles that we found, but were not included in the analysis, explored the transformation that mental health services underwent from providing solely in-person care before the pandemic to providing DHI during the health crisis. The authors of these studies highlighted the opportunity that the crisis provided in the field to transform health care practices [<xref ref-type="bibr" rid="ref56">56</xref>-<xref ref-type="bibr" rid="ref58">58</xref>].</p>
      </sec>
      <sec>
        <title>Preference for In-Person Interventions or DHI</title>
        <p>We found 3 studies where adolescents and children preferred in-person interventions to DHIs [<xref ref-type="bibr" rid="ref24">24</xref>,<xref ref-type="bibr" rid="ref39">39</xref>,<xref ref-type="bibr" rid="ref51">51</xref>]. Of these, 2 were exploratory studies, and therefore, participants had no hands-on experience with DHIs [<xref ref-type="bibr" rid="ref39">39</xref>,<xref ref-type="bibr" rid="ref51">51</xref>]. The authors of one of these 2 studies suggested that an initial meeting about DHIs with a clinician to explain the potential benefits of DHIs could improve engagement [<xref ref-type="bibr" rid="ref51">51</xref>]. The third study concerned a mental and general health educational program delivered using teleconferencing. In that study, although adolescents found the content useful, most of them stated that they would rather prefer the program to be delivered in person to foster encounters with peers [<xref ref-type="bibr" rid="ref24">24</xref>]. In contrast, 3 other studies highlighted that children and adolescents preferred DHIs to in-person interventions. The first DHI was a videoconference for medical examination; participants preferred it because it reduced anxiety related to meeting a mental health care professional [<xref ref-type="bibr" rid="ref50">50</xref>]. The second was an internet site; participants preferred using it to in-person encounters, as it avoided mental health stigma [<xref ref-type="bibr" rid="ref38">38</xref>]. The third DHI was a video game that delivered mental and general health education; participants indicated that they preferred its recreational dimension to traditional classes [<xref ref-type="bibr" rid="ref43">43</xref>]. Logically, the preference between in-person interventions and DHIs should be explored only when the proposed service already exists in an in-person setting. In this regard, for a DHI to be the preferred choice, it should offer more features and accordingly be perceived as more useful.</p>
      </sec>
      <sec>
        <title>DHIs Modify the Affordance of Mental Health Care</title>
        <p>In our review on DHIs, we gathered data showing that adolescents, children, and their parents were satisfied with the technologies used, the capabilities they offered, and their features. Many of the 30 included studies reported that DHI users were eager to use DHIs. Users sought interventions that were easy to use, flexible, customizable, and aesthetically pleasing [<xref ref-type="bibr" rid="ref27">27</xref>]. These characteristics enhance their affordance, which is the relational structure between an object or technology and the user that enables or constrains all potential behaviors in a given context [<xref ref-type="bibr" rid="ref59">59</xref>].</p>
        <p>The ability to customize one’s experience when using a DHI is a valuable feature of these interventions that contributes to good affordance. For example, users can customize the interface and enable or disable geographical location [<xref ref-type="bibr" rid="ref34">34</xref>,<xref ref-type="bibr" rid="ref52">52</xref>]. They can also choose to install or uninstall smartphone apps. Once installed, an app may be activated in the background and consulted whenever and wherever needed to seek help at any given moment. In our review, users appreciated their ability to attend group therapy sessions from a remote location [<xref ref-type="bibr" rid="ref24">24</xref>].</p>
        <p>DHIs offer autonomy of use coupled with greater freedom in care seeking. Their use removes the barriers between daily living activities and engagement in care seeking.</p>
        <p>In our review, the suitability of an intervention to children’s and adolescents’ culture was important for them. Features such as the tone of the intervention and the design of the video game characters were appreciated [<xref ref-type="bibr" rid="ref29">29</xref>,<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref44">44</xref>]. Suitability and usability were identified as influencing factors in the engagement of children and young people in a 2022 review by Liverpool et al [<xref ref-type="bibr" rid="ref7">7</xref>]. The authors found that these characteristics facilitated the link between the user and the DHI and, therefore, between the user and the care delivered. Consequently, DHIs modify the affordance of mental health care.</p>
      </sec>
      <sec>
        <title>The Influence of Connectedness on DHI Use</title>
        <p>In our review, an important DHI feature that adolescents sought was social connection [<xref ref-type="bibr" rid="ref24">24</xref>,<xref ref-type="bibr" rid="ref34">34</xref>,<xref ref-type="bibr" rid="ref38">38</xref>]. Adolescents stated that seeking help involved other people in the same way that a feeling of connection to others provides help in itself [<xref ref-type="bibr" rid="ref38">38</xref>]. Receiving support from other people experiencing the same type of mental health problems was helpful and came via anonymous social messaging to ensure connection and privacy [<xref ref-type="bibr" rid="ref34">34</xref>]. Adolescents also appreciated the opportunity provided by videoconferencing to meet peers and discuss mental and general health education issues [<xref ref-type="bibr" rid="ref24">24</xref>]. Connectedness was both a physical link enabling connection and a subjective feeling of being related to others; it was related to mental health well-being [<xref ref-type="bibr" rid="ref60">60</xref>]. In the review by Liverpool et al [<xref ref-type="bibr" rid="ref7">7</xref>], a sense of connectedness was identified as a major feature that DHIs should provide to ensure better engagement of adolescents and children in these types of interventions. The same authors argued that connectedness should allow people to seek support from professionals and peers in a way that allows privacy and security [<xref ref-type="bibr" rid="ref7">7</xref>].</p>
      </sec>
      <sec>
        <title>Attitudes to DHIs Are Related to Trust and Fear of Stigmatization</title>
        <p>We have observed that DHIs can increase the affordance of mental health care (ie, the understanding of the mental health care offer, its accessibility, and ease of use) and promote connectedness; the consequence of this is improved access to treatment for children and adolescents. However, increased connectedness must not be detrimental to data security and confidentiality. Some adolescents and children in our review mentioned that they were afraid of being seen with a DHI app installed on their smartphones [<xref ref-type="bibr" rid="ref34">34</xref>]. Others were concerned about the data recorded and who might access them [<xref ref-type="bibr" rid="ref27">27</xref>]. For some, accessing mental health care through a DHI was associated with a fear of stigmatization, linked to the worry that privacy and confidentiality could not be guaranteed using digital technology. The technologies used by DHIs must therefore be secure to facilitate engagement. In the review by Liverpool et al [<xref ref-type="bibr" rid="ref7">7</xref>], trust and anonymity were found to promote engagement in DHIs [<xref ref-type="bibr" rid="ref7">7</xref>].</p>
      </sec>
      <sec>
        <title>Implications and Recommendations</title>
        <p>Effective use of DHIs by target audiences depends on numerous factors. In our opinion, engagement in a DHI depends on user needs and the ability of the intervention to successfully meet these needs. More specifically, the success of a DHI depends on understanding the target population’s culture and lifestyle, the difficulties that this population encounters in terms of mental health problems, and the usefulness of the intervention. DHIs should be suitable, usable, customizable, secure, and trustworthy and should facilitate connectedness. The scope and objectives of the DHI should be understandable by the user, and support should be provided throughout the duration of its use. Future research should explore the needs and specificity of the target audience. Researchers should work with the target audience and with professionals to elicit features that could be useful. This scoping review could be used as the first step of a thorough systematic literature review of children’s, adolescents’, and their parents’ attitudes toward the DHI they already use.</p>
      </sec>
      <sec>
        <title>Strengths and Limitations</title>
        <p>The work described here followed established guidelines for scoping reviews [<xref ref-type="bibr" rid="ref20">20</xref>]. We analyzed the literature and identified the themes that were studied. We considered the different types of publications, the technologies used, the distressing mental experiences studied, and the populations concerned. The results of our review provide a better understanding of the existing literature and how research in this area has been conducted. However, this review had several limitations. First, there is a risk of assessment bias because the first author performed both the study selection (ie, inclusion and exclusion) and data extraction phases alone. Second, some studies may have been missed despite our best efforts to include as many papers as possible. Third, there may have been some variation or inconsistency when grouping the results of studies under themes, as the theme definitions may partially overlap. Fourth, the variety of methodologies used in the 30 included studies made accurate comparisons difficult. Fifth, we were unable to retrieve any articles exploring the COVID-19 response that matched our inclusion criteria. This limitation could be addressed by further research. Finally, although not a limitation per se, associations between the attitudes of children and adolescents to DHIs and their use of ICT were not investigated in the articles reviewed. Familiarity with ICT could be a determining factor of DHI use and needs further investigation to better understand engagement in DHIs.</p>
      </sec>
      <sec>
        <title>Conclusions</title>
        <p>The results of our scoping review show that the children and adolescents studied had a positive attitude toward DHIs. Five major themes regarding attitudes were addressed by the reviewed articles: satisfaction, preferences, use, perception, and needs. These 5 themes should be considered in future research.</p>
        <p>We found that the experience of DHI use was a determining factor of attitudes toward these interventions. The fear of stigma in children and adolescents was associated with their propensity to use DHIs. More specifically, DHIs were perceived both as a means to avoid stigmatization and to trigger it. The connectedness of DHIs was very much sought after by adolescents and was considered a key element in mental health care. Owing to the suitability and ease of use of DHIs, participants from different studies felt that these interventions improved the affordance of mental health care.</p>
        <p>In addition, the autonomy and freedom of use provided by DHIs erased the barriers between everyday life and engagement in seeking care. Although adolescents particularly seek connectedness, ICT allows people seeking help to reach out, maintain, and increase the connection they have with their care providers, thus modifying the healer-healed relationship.</p>
        <p>The scalability and availability of DHIs could help reshape mental health care delivery, making it more wide-ranging and more accessible. Owing to the immediacy and transportability inherent in DHIs, the moment when and the place where mental health care is delivered can be more easily modified to best suit a patient’s lifestyle.</p>
        <p>Finally, DHIs can help address the treatment gap in the mental health of children and adolescents, as both users and professionals can benefit from them. As the interest in DHIs grows, researchers and programmers should first investigate all the dimensions related to the target public’s attitudes toward DHIs to ensure better engagement.</p>
      </sec>
    </sec>
  </body>
  <back>
    <app-group>
      <supplementary-material id="app1">
        <label>Multimedia Appendix 1</label>
        <p>Databases search strategy.</p>
        <media xlink:href="jmir_v25i1e43102_app1.docx" xlink:title="DOCX File , 16 KB"/>
      </supplementary-material>
      <supplementary-material id="app2">
        <label>Multimedia Appendix 2</label>
        <p>PRISMA-ScR (Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews) checklist.</p>
        <media xlink:href="jmir_v25i1e43102_app2.pdf" xlink:title="PDF File  (Adobe PDF File), 498 KB"/>
      </supplementary-material>
    </app-group>
    <glossary>
      <title>Abbreviations</title>
      <def-list>
        <def-item>
          <term id="abb1">ASD</term>
          <def>
            <p>autism spectrum disorder</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb2">DHI</term>
          <def>
            <p>digital health intervention</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb3">ICT</term>
          <def>
            <p>information and communications technology</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb4">PRISMA-ScR</term>
          <def>
            <p>Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews</p>
          </def>
        </def-item>
      </def-list>
    </glossary>
    <ack>
      <p>The authors would like to thank Jude Sweeney for editing this manuscript.</p>
    </ack>
    <fn-group>
      <fn fn-type="conflict">
        <p>None declared.</p>
      </fn>
    </fn-group>
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