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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JMIR</journal-id>
      <journal-id journal-id-type="nlm-ta">J Med Internet Res</journal-id>
      <journal-title>Journal of Medical Internet Research</journal-title>
      <issn pub-type="epub">1438-8871</issn>
      <publisher>
        <publisher-name>JMIR Publications</publisher-name>
        <publisher-loc>Toronto, Canada</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">v25i1e41939</article-id>
      <article-id pub-id-type="pmid">36645703</article-id>
      <article-id pub-id-type="doi">10.2196/41939</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Review</subject>
        </subj-group>
        <subj-group subj-group-type="article-type">
          <subject>Review</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>The Use of Technology to Provide Mental Health Services to Youth Experiencing Homelessness: Scoping Review</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="editor">
          <name>
            <surname>Leung</surname>
            <given-names>Tiffany</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Musker</surname>
            <given-names>Michael</given-names>
          </name>
        </contrib>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Karnik</surname>
            <given-names>Niranjan</given-names>
          </name>
        </contrib>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Rufa</surname>
            <given-names>Anne</given-names>
          </name>
        </contrib>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Kidd</surname>
            <given-names>Sean</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib id="contrib1" contrib-type="author" corresp="yes">
          <name name-style="western">
            <surname>Lal</surname>
            <given-names>Shalini</given-names>
          </name>
          <degrees>BScOT, MSc, PhD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <address>
            <institution>School of Rehabilitation</institution>
            <institution>Faculty of Medicine</institution>
            <institution>University of Montréal</institution>
            <addr-line>C.P. 6128, succursale Centre-ville</addr-line>
            <addr-line>Montréal, QC, H3C 3J7</addr-line>
            <country>Canada</country>
            <phone>1 5148908000 ext 31581</phone>
            <email>shalini.lal@umontreal.ca</email>
          </address>
          <xref rid="aff2" ref-type="aff">2</xref>
          <xref rid="aff3" ref-type="aff">3</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-7501-5018</ext-link>
        </contrib>
        <contrib id="contrib2" contrib-type="author">
          <name name-style="western">
            <surname>Elias</surname>
            <given-names>Sarah</given-names>
          </name>
          <degrees>MScOT</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <xref rid="aff2" ref-type="aff">2</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-8611-8899</ext-link>
        </contrib>
        <contrib id="contrib3" contrib-type="author">
          <name name-style="western">
            <surname>Sieu</surname>
            <given-names>Vida</given-names>
          </name>
          <degrees>MScOT</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <xref rid="aff2" ref-type="aff">2</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0003-1608-2648</ext-link>
        </contrib>
        <contrib id="contrib4" contrib-type="author">
          <name name-style="western">
            <surname>Peredo</surname>
            <given-names>Rossana</given-names>
          </name>
          <degrees>MD, PhD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <xref rid="aff2" ref-type="aff">2</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-2153-8227</ext-link>
        </contrib>
      </contrib-group>
      <aff id="aff1">
        <label>1</label>
        <institution>School of Rehabilitation</institution>
        <institution>Faculty of Medicine</institution>
        <institution>University of Montréal</institution>
        <addr-line>Montréal, QC</addr-line>
        <country>Canada</country>
      </aff>
      <aff id="aff2">
        <label>2</label>
        <institution>Youth Mental Health and Technology Lab</institution>
        <institution>Health Innovation and Evaluation Hub</institution>
        <institution>University of Montréal Hospital Research Centre</institution>
        <addr-line>Montréal, QC</addr-line>
        <country>Canada</country>
      </aff>
      <aff id="aff3">
        <label>3</label>
        <institution>Douglas Mental Health University Institute</institution>
        <addr-line>Montréal, QC</addr-line>
        <country>Canada</country>
      </aff>
      <author-notes>
        <corresp>Corresponding Author: Shalini Lal <email>shalini.lal@umontreal.ca</email></corresp>
      </author-notes>
      <pub-date pub-type="collection">
        <year>2023</year>
      </pub-date>
      <pub-date pub-type="epub">
        <day>16</day>
        <month>1</month>
        <year>2023</year>
      </pub-date>
      <volume>25</volume>
      <elocation-id>e41939</elocation-id>
      <history>
        <date date-type="received">
          <day>16</day>
          <month>8</month>
          <year>2022</year>
        </date>
        <date date-type="rev-request">
          <day>15</day>
          <month>9</month>
          <year>2022</year>
        </date>
        <date date-type="rev-recd">
          <day>17</day>
          <month>10</month>
          <year>2022</year>
        </date>
        <date date-type="accepted">
          <day>20</day>
          <month>10</month>
          <year>2022</year>
        </date>
      </history>
      <copyright-statement>©Shalini Lal, Sarah Elias, Vida Sieu, Rossana Peredo. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 16.01.2023.</copyright-statement>
      <copyright-year>2023</copyright-year>
      <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
        <p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Journal of Medical Internet Research, is properly cited. The complete bibliographic information, a link to the original publication on https://www.jmir.org/, as well as this copyright and license information must be included.</p>
      </license>
      <self-uri xlink:href="https://www.jmir.org/2023/1/e41939" xlink:type="simple"/>
      <abstract>
        <sec sec-type="background">
          <title>Background</title>
          <p>There is growing interest in using information and communication technologies (ICTs) to improve access to mental health services for youth experiencing homelessness (YEH); however, limited efforts have been made to synthesize this literature.</p>
        </sec>
        <sec sec-type="objective">
          <title>Objective</title>
          <p>This study aimed to review the research on the use of ICTs to provide mental health services and interventions for YEH.</p>
        </sec>
        <sec sec-type="methods">
          <title>Methods</title>
          <p>We used a scoping review methodology following the Arksey and O’Malley framework and guidelines from the Joanna Briggs Institute Manual for Evidence Synthesis. The results are reported according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) statement and the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews). A systematic search was conducted from 2005 to 2021 in MEDLINE, Embase, CINAHL, PsycInfo, Cochrane, Web of Science, and Maestro and in ProQuest Thesis and Dissertations, Papyrus, Homeless Hub, and Google Scholar for gray literature. Studies were included if participants’ mean age was between 13 and 29 years, youth with mental health issues were experiencing homelessness or living in a shelter, ICTs were used as a means of intervention, and the study provided a description of the technology. The exclusion criteria were technology that did not allow for interaction (eg, television) and languages other than French or English. The data were analyzed using descriptive statistics and qualitative approaches. Two reviewers were involved in the screening and data extraction process in consultation with a third reviewer. The data were summarized in tables and by narrative synthesis.</p>
        </sec>
        <sec sec-type="results">
          <title>Results</title>
          <p>From the 2153 abstracts and titles screened, 12 were included in the analysis. The most common types of ICTs used were communication technologies (eg, phone, video, and SMS text messages) and mobile apps. The intervention goals varied widely across studies; the most common goal was reducing risky behaviors, followed by addressing cognitive functioning, providing emotional support, providing vital resources, and reducing anxiety. Most studies (9/11, 82%) focused on the feasibility of interventions. Almost all studies reported high levels of acceptability (8/9, 89%) and moderate to high frequency of use (5/6, 83%). The principal challenges were related to technical problems such as the need to replace phones, issues with data services, and phone charging.</p>
        </sec>
        <sec sec-type="conclusions">
          <title>Conclusions</title>
          <p>Our results indicate the emerging role of ICTs in the delivery of mental health services to YEH and that there is a high level of acceptability based on early feasibility studies. However, our results should be interpreted cautiously, considering the limited number of studies included in the analysis and the elevated levels of dropout. There is a need to advance efficacy and effectiveness research in this area with larger and longer studies.</p>
        </sec>
        <sec sec-type="registered-report">
          <title>International Registered Report Identifier (IRRID)</title>
          <p>RR2-10.1136/bmjopen-2022-061313</p>
        </sec>
      </abstract>
      <kwd-group>
        <kwd>digital equity</kwd>
        <kwd>homelessness</kwd>
        <kwd>telemedicine</kwd>
        <kwd>telehealth</kwd>
        <kwd>cellular phone</kwd>
        <kwd>internet</kwd>
        <kwd>e-mental health</kwd>
        <kwd>digital health</kwd>
        <kwd>mobile health</kwd>
        <kwd>mHealth</kwd>
        <kwd>literature review</kwd>
        <kwd>mobile phone</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec sec-type="introduction">
      <title>Introduction</title>
      <sec>
        <title>Background</title>
        <p>Homelessness is a rapidly growing phenomenon that is estimated to affect approximately 1.6 billion people worldwide by 2025 [<xref ref-type="bibr" rid="ref1">1</xref>]. It is of particular concern that youth represent 20% to 30% of the homeless population in developed countries (ie, Canada and Australia) [<xref ref-type="bibr" rid="ref2">2</xref>,<xref ref-type="bibr" rid="ref3">3</xref>]. The factors that contribute to homelessness in this population are multifaceted, such as lack of affordable housing or social support, barriers to completing education, economic insecurity, family conflict or domestic violence, addiction, and involvement in the child welfare system [<xref ref-type="bibr" rid="ref4">4</xref>,<xref ref-type="bibr" rid="ref5">5</xref>].</p>
        <p>Moreover, because of their precarious situation, youth experiencing homelessness (YEH) may not develop the skills needed for a healthy and secure transition to adulthood [<xref ref-type="bibr" rid="ref6">6</xref>]. Indeed, YEH are at a high risk of physical and mental health problems [<xref ref-type="bibr" rid="ref7">7</xref>-<xref ref-type="bibr" rid="ref9">9</xref>], with potential consequences such as nutritional vulnerability, drug use, exposure to premature sexual activity, physical abuse, sexual abuse, criminal victimization, dropping out of school, boredom, and poor access to the resources needed to maintain a satisfactory standard of living [<xref ref-type="bibr" rid="ref10">10</xref>-<xref ref-type="bibr" rid="ref14">14</xref>]. However, despite the clear need to provide easy access to mental health services, the traditional health care system is challenged by the nomadic lifestyle of YEH, compounding the difficulties in reaching and engaging this marginalized population [<xref ref-type="bibr" rid="ref15">15</xref>,<xref ref-type="bibr" rid="ref16">16</xref>].</p>
        <p>High rates of access and use of technology among YEH have been reported in the literature, even among very young populations [<xref ref-type="bibr" rid="ref17">17</xref>], and therefore, may be a medium for health care providers to reach and engage YEH [<xref ref-type="bibr" rid="ref18">18</xref>-<xref ref-type="bibr" rid="ref20">20</xref>]. For instance, a recent scoping review [<xref ref-type="bibr" rid="ref20">20</xref>] found high percentages (ranging from 46.7% to 100%) of mobile phone ownership among 16 YEH samples and reported that, on average, 77.1% (range 57%-90.7%) of the samples used social media. This indicates that YEH are receptive to using information and communication technologies (ICTs) in their daily lives and for health purposes.</p>
        <p>Indeed, there is growing interest in the potential use of ICTs to deliver health and mental health–related services and interventions to low-income and disadvantaged populations [<xref ref-type="bibr" rid="ref18">18</xref>-<xref ref-type="bibr" rid="ref24">24</xref>]. Systematic reviews indicate that the most common type of ICTs for mental health explored in recent years are videoconferencing, SMS text messaging, and mobile apps [<xref ref-type="bibr" rid="ref20">20</xref>,<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref26">26</xref>], but it should be noted that most reviews do not focus on the YEH population.</p>
      </sec>
      <sec>
        <title>Research Questions</title>
        <p>Given the emerging research on this topic and the need to synthesize this literature to inform future policy, practice, and research, we conducted a scoping review to answer the following question: What is known about the use of technology to provide mental health services and interventions to YEH aged between 13 and 29 years?</p>
        <p>To answer this research question, we aimed to</p>
        <list list-type="order">
          <list-item>
            <p>describe the type of ICTs, goal, and type of service or intervention (eg, information, education, therapy, or peer-support); prescribed frequency of use; characteristics (eg, self-directed, coached, or type of professional delivering the service); and technology type (eg, phones or web-based applications).</p>
          </list-item>
          <list-item>
            <p>describe the available evidence on technology-based mental health interventions (including acceptability, feasibility, security, and effectiveness).</p>
          </list-item>
          <list-item>
            <p>document the quality of the available evidence.</p>
          </list-item>
          <list-item>
            <p>identify the implications of this evidence for mental health services.</p>
          </list-item>
        </list>
      </sec>
    </sec>
    <sec sec-type="methods">
      <title>Methods</title>
      <sec>
        <title>Overview</title>
        <p>This study was conducted according to the scoping review framework suggested by Arksey and O’Malley [<xref ref-type="bibr" rid="ref27">27</xref>], the methodological guidelines of Levac et al [<xref ref-type="bibr" rid="ref28">28</xref>], and the Joanna Briggs Institute Manual for Evidence Synthesis [<xref ref-type="bibr" rid="ref29">29</xref>]. The protocol was developed a priori, registered retrospectively on the Open Science Framework [<xref ref-type="bibr" rid="ref30">30</xref>], and published under peer review [<xref ref-type="bibr" rid="ref31">31</xref>]. Results are reported according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) statement for reporting systematic reviews [<xref ref-type="bibr" rid="ref32">32</xref>] and scoping reviews (PRISMA-ScR [Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews]) [<xref ref-type="bibr" rid="ref33">33</xref>]. The completed PRISMA-ScR checklist is provided in <xref ref-type="supplementary-material" rid="app1">Multimedia Appendix 1</xref>.</p>
      </sec>
      <sec>
        <title>Information Sources and Search Strategy</title>
        <p>To identify all relevant studies, a literature search was conducted in the following electronic databases: MEDLINE, Embase, CINAHL, PsycInfo, Cochrane, Web of Science, and Maestro, mainly for peer-reviewed articles; and ProQuest Thesis and Dissertations, Papyrus, Homeless Hub, and Google Scholar for gray literature. No methodological restrictions were applied, and all publications in English or French, from January 1, 2005, to May 28, 2021, were included. Publication date restrictions were chosen, given that the evolution of technology limits the applicability of the literature search; thus, literature published before 2005 would not be as pertinent to the current landscape of research and practice. Abstracts and conference presentations were included only if the authors reported sufficient details to address the objectives of this review.</p>
        <p>The search strategy was developed through consultation with an information specialist. It was adapted from our previous scoping review [<xref ref-type="bibr" rid="ref20">20</xref>] that focused on the access and use of technology among YEH by adding the concept of mental health. Most databases were searched on May 28, 2021, except for Web of Sciences, which was searched on August 9, 2021. <xref ref-type="boxed-text" rid="box1">Textbox 1</xref> presents the search strategy used in MEDLINE.</p>
        <boxed-text id="box1" position="float">
          <title>Search strategy used in MEDLINE (the search strategy was adapted for each database under the supervision of an information specialist).</title>
          <p>(exp “Internet” OR exp “Cell Phone” OR exp “Smartphone” OR exp “Computers” OR exp “Computers Handheld” OR exp “Mobile Applications” OR exp “Telemedicine” OR exp “Social Media” OR exp “Technology” OR exp “Medical Records Systems, Computerized” OR exp “Electronic Mail” OR exp “Social Networking” OR exp “User-Computer Interface” OR exp “Web Browser” OR exp “Virtual Reality Exposure Therapy” OR exp “Virtual Reality” OR exp “Computer Simulation” OR exp “video-audio media” OR exp “Robotics” OR exp “Wearable Electronic Devices” OR exp “Biosensing Techniques” OR exp “Video Recording” OR exp “Online Systems” OR (“internet” or “cell phone*” or “cellphone*” or “mobile phone*” or “smart phone*” or “smartphone*” or “mobile app*” or “computer*” or “social media*” or “Facebook” or “text messag*” or “electronic messag*” or “electronic mail*” or “email*” or “e-mail*” or “social network*” or “technolog*” or “electronic case* management” or “web” or “website*” or “virtual reality” or “mobile device*” or “video*” or “portal*” or “chatbot*” or “robot*” or “wearable device*” or “sensor” or “sensors” or “biosensoror” or “bio-sensor” or “biosensors” or “bio-sensors” or “smartwatch*” or “smart watch*” or “ereferr*” or “e-referr*” or “chat” or “online” or “instant messag*” or “cyber*” or “avatar*” or “platform*” or “telehealth*” or “tele-health*” or “telepsychiatry” or “tele-psychiatry” or “telepsychology” or “tele-psychology” or “telemental health*” or “tele-mental health*” or “teletherapy” or “tele-therapy” or “telemedicine” or “tele-medicine” or “telerehabilitation” or “tele-rehabilitation” or “emental health*” or “e-mental health*” or “ehealth*” or “e-health*” or “mhealth*” or “m-health*”). ab,kf,kw,ti) AND (exp “Homeless Persons” OR (“homeless*” or “street* youth*” or “street* adolescen*” or “street* teen*” or “runaway youth*” or “runaway adolescen*” or “runaway teen*” or “street* living youth*” or “street* living adolescen*” or “street* living teen*”). ab,kf,kw,ti), limit to (yr=“2005 -Current” and (english or french))</p>
        </boxed-text>
      </sec>
      <sec>
        <title>Selection of Sources of Evidence</title>
        <p>All references generated by the electronic search were exported into Covidence systematic review software. After duplicates were removed, 2 authors (SE and VS) independently screened all titles and abstracts based on the inclusion and exclusion criteria. Next, full-text screening was conducted by the same 2 authors. All discrepancies were resolved through discussion, and a third author (SL) was included in the case of disagreement until consensus was reached. The third author (SL) reviewed all included papers in relation to the inclusion and exclusion criteria as a final validation step.</p>
        <p>Inclusion criteria were as follows: (1) primary studies reporting on participants with a mean age between 13 and 29 years; (2) youth with any mental health issue experiencing homelessness (including living in a shelter); (3) use of ICTs as a means of intervention to address mental health treatment, mental health promotion, socioeconomic determinants pertinent to mental health, or daily activities such as maintaining housing, returning to school or work, and so on; and (4) a description of the technology used. Studies were excluded if the authors used technology that did not allow the user to interact with it (eg, CDs, projectors, or television) and literature written in languages other than French or English.</p>
      </sec>
      <sec>
        <title>Data Extraction and Synthesis</title>
        <p>The data extraction form was adapted from our previous scoping review [<xref ref-type="bibr" rid="ref20">20</xref>] using Microsoft Excel. The form was piloted by 2 authors (SE and VS) who independently extracted data from 3 studies and compared their results in consultation with a third author (SL). Revisions were made to ensure that relevant information pertinent to the objectives was included.</p>
        <p>The following data were extracted: (1) study characteristics, including authors, publication year, country of publication, study objectives, study design, methods, sample size, sociodemographic characteristics, dropout percentages, and follow-up; (2) intervention characteristics, including type of ICTs, technology features, implementation, and length and frequency of intervention; and (3) specific outcomes of the intervention according to the feasibility study framework by Bowen et al [<xref ref-type="bibr" rid="ref34">34</xref>], which includes acceptability, degree of success of execution, and failure of execution. The data extraction process was conducted separately by 2 authors (SE and VS), and each of these authors validated the other’s data extraction and resolved any discrepancies. The completed data extraction form was validated by another author (RP). Publication reporting of data from the same study sample was considered a set and assessed as one study.</p>
        <p>Data were summarized in tables and by a narrative synthesis organized according to themes pertaining to the objectives of the scoping review. Statistical analyses included simple weighted averages for continuous data (participant age), and frequencies and percentages were calculated for all other categorical data. Qualitative data (eg, intervention characteristics, acceptability, and implementation) were coded and categorized by RP and then validated by SL.</p>
      </sec>
      <sec>
        <title>Quality Appraisal</title>
        <p>The methodological quality of the included studies was assessed to obtain a general idea regarding the quality of the publications. This was performed by an author (RP) using the critical appraisal tools provided by the Joanna Briggs Institute [<xref ref-type="bibr" rid="ref35">35</xref>]. Meta-biases such as publication bias and selective reporting were not analyzed. The type of evidence was categorized based on the Joanna Briggs Institute Manual for Evidence Synthesis [<xref ref-type="bibr" rid="ref35">35</xref>].</p>
      </sec>
    </sec>
    <sec sec-type="results">
      <title>Results</title>
      <sec>
        <title>Overview</title>
        <p>An electronic search identified 2153 unique records. After the first level of title and abstract screening, 4.37% (94/2153) of documents were retained for the second screening level that included a full-text review. Of these, 13% (12/94) of reports were selected for inclusion in the scoping review. The interrater reliability coefficient indicated moderate agreement for the first screening level (Cohen κ=0.4138) and almost perfect agreement for the second level (Cohen κ=0.877). Two reports (a poster and published abstract) identified during the screening process described the same study and population [<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref37">37</xref>]. We decided to focus mainly on data from the poster [<xref ref-type="bibr" rid="ref36">36</xref>] because it contained the most information. In addition, 2 other reports, Linnemayr et al [<xref ref-type="bibr" rid="ref38">38</xref>] and Tucker et al [<xref ref-type="bibr" rid="ref39">39</xref>], reported data concerning the same study intervention but including different sample populations. Tucker et al [<xref ref-type="bibr" rid="ref39">39</xref>] focused on refining the intervention by examining its acceptability and feasibility, while Linnemayr et al [<xref ref-type="bibr" rid="ref38">38</xref>] conducted a pilot study assessing the same intervention with a larger sample. We considered these to be 2 different studies only when new information was added. In total, 12 reports from 11 studies were included in the analysis. Further details about the screening process are described in the PRISMA flowchart in <xref rid="figure1" ref-type="fig">Figure 1</xref>. The flowchart is in accordance with the PRISMA 2020 statement for reporting systematic reviews [<xref ref-type="bibr" rid="ref32">32</xref>].</p>
        <fig id="figure1" position="float">
          <label>Figure 1</label>
          <caption>
            <p>PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) flowchart for study selection. ICT: information and communication technology.</p>
          </caption>
          <graphic xlink:href="jmir_v25i1e41939_fig1.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
        </fig>
      </sec>
      <sec>
        <title>Overview of the Studies</title>
        <p>All studies were conducted in North America, with the majority (10/11, 91%) conducted in the United States (Chicago, Los Angeles, Oakland, and other nonspecified cities located in the northeast and midwestern states) and one conducted in Canada (abstract; study location unspecified). Although our search strategy was extended to 2005, all reports were published between 2016 and 2021 and thus published within the last 5 years of conducting the scoping review. In terms of the types of documents reviewed, the majority (9/12, 75%) of the reports were peer-reviewed articles, and the rest were conference abstracts (2/12, 17%) and a poster (1/12, 8%). All studies were conducted in the early phase of the research (eg, intervention development, feasibility, and preliminary efficacy). Additional details of the study characteristics are provided in the latter part of the Results section.</p>
      </sec>
      <sec>
        <title>Sample Characteristics</title>
        <p>Sample characteristics are presented in <xref ref-type="table" rid="table1">Table 1</xref>. Sample sizes across studies ranged from 6 to 99 participants, resulting in a total sample of 526 participants included in this scoping review. Participant ages ranged from 13 to 25 years across studies; 42.8% (225/526) identified as women, 41.1% (216/526) as men, and 2.9% (15/526) as transgender or gender fluid. Among the 3 studies that reported on sexuality [<xref ref-type="bibr" rid="ref38">38</xref>,<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref41">41</xref>], most participants (135/526, 25.7%) were heterosexual, 3.2% (17/526) were homosexual or bisexual, and 5.1% (27/526) reported other as sexuality. A total of 9 studies [<xref ref-type="bibr" rid="ref19">19</xref>,<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref38">38</xref>,<xref ref-type="bibr" rid="ref40">40</xref>-<xref ref-type="bibr" rid="ref45">45</xref>] reported ethnicity; 42.9% (226/526) of the participants were Black and African American, 11% (58/526) were Hispanic and Latin American, 9.3% (49/526) were White, 6.8% (36/526) were mixed, and 4.9% (26/526) were other ethnicities. Regarding mental illness conditions, 6 studies [<xref ref-type="bibr" rid="ref19">19</xref>,<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref43">43</xref>-<xref ref-type="bibr" rid="ref46">46</xref>] included participants who were diagnosed with a psychiatric disorder (dysthymia, depression and bipolar disorder, anxiety, posttraumatic stress disorder, adjustment disorder, psychosis, attention-deficit hyperactivity disorder, personality disorders, or emotion regulation issues), 5 studies (6 reports) [<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref38">38</xref>,<xref ref-type="bibr" rid="ref39">39</xref>,<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref44">44</xref>,<xref ref-type="bibr" rid="ref45">45</xref>] included participants who used or abused substances such as alcohol, tobacco, or marijuana, and 2 studies [<xref ref-type="bibr" rid="ref41">41</xref>,<xref ref-type="bibr" rid="ref43">43</xref>] included only participants without any type of mental disorder. <xref ref-type="table" rid="table1">Table 1</xref> also shows that 4 studies [<xref ref-type="bibr" rid="ref19">19</xref>,<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref42">42</xref>] recruited participants from homeless shelters, and the rest recruited participants from transitional housing [<xref ref-type="bibr" rid="ref43">43</xref>,<xref ref-type="bibr" rid="ref45">45</xref>], drop-in center [<xref ref-type="bibr" rid="ref38">38</xref>,<xref ref-type="bibr" rid="ref39">39</xref>,<xref ref-type="bibr" rid="ref44">44</xref>], or various other services [<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref41">41</xref>] for YEH.</p>
        <table-wrap position="float" id="table1">
          <label>Table 1</label>
          <caption>
            <p>Sample demographic and study characteristics of the 11 studies included in the review<sup>a</sup>.</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="30"/>
            <col width="770"/>
            <col width="200"/>
            <thead>
              <tr valign="top">
                <td colspan="2">Characteristics</td>
                <td>Values</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td colspan="2">Sample<sup>b</sup> size (n), range</td>
                <td>6-99</td>
              </tr>
              <tr valign="top">
                <td colspan="2">Age (years), range<sup>c</sup></td>
                <td>13-25</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>YEH<sup>d</sup> sample from studies that examined gender (n=526), n (%)</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Women</td>
                <td>225 (42.8)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Men</td>
                <td>216 (41.1)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Transgender</td>
                <td>10 (1.9)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Gender fluid</td>
                <td>5 (1)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Unknown or missing information</td>
                <td>70 (13.3)</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>YEH sample from studies that examined sexuality (n=526), n (%)</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Heterosexual</td>
                <td>135 (25.7)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Homosexual</td>
                <td>9 (1.7)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Bisexual</td>
                <td>8 (1.5)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Other</td>
                <td>27 (5.1)</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>YEH sample from studies that examined ethnicity (n=526), n (%)</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Black</td>
                <td>226 (42.9)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Hispanic</td>
                <td>58 (11)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>White</td>
                <td>49 (9.3)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Mixed race</td>
                <td>36 (6.8)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Other</td>
                <td>26 (4.9)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Unknown or missing information</td>
                <td>27 (5.1)</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Studies that specified mental illness or conditions<sup>e</sup> (n=11), n (%)</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Psychiatric disorders (dysthymia, depression, bipolar disorder, anxiety, PTSD<sup>f</sup>, adjustment disorders, psychosis, ADHD<sup>g</sup>, emotion regulation, or personality disorders)</td>
                <td>6 (54.5)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Substance use (alcohol, tobacco, or marijuana)</td>
                <td>5 (45.5)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>None</td>
                <td>2 (18.2)</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Studies that specified places of YEH recruitment (n=11), n (%)</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Shelter</td>
                <td>4 (36.4)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Transitional housing</td>
                <td>2 (18.2)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Drop-in centers</td>
                <td>2 (18.2)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Various services for YEH</td>
                <td>2 (18.2)</td>
              </tr>
            </tbody>
          </table>
          <table-wrap-foot>
            <fn id="table1fn1">
              <p><sup>a</sup>Tucker et al [<xref ref-type="bibr" rid="ref39">39</xref>] and Linnemayr et al [<xref ref-type="bibr" rid="ref38">38</xref>] analyzed the same population. This table only includes data from the study by Linnemayr et al [<xref ref-type="bibr" rid="ref38">38</xref>], because this report had the largest population.</p>
            </fn>
            <fn id="table1fn2">
              <p><sup>b</sup>Total number of participants allocated to each intervention and those who completed baseline assessments.</p>
            </fn>
            <fn id="table1fn3">
              <p><sup>c</sup>Age range was obtained from the age ranges provided as inclusion criteria by each study, except for the studies by Glover et al [<xref ref-type="bibr" rid="ref40">40</xref>] and Thompson et al [<xref ref-type="bibr" rid="ref42">42</xref>], who reported the actual sample age range. Two studies [<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref47">47</xref>] did not report on age ranges, but their mean ages were 19.13 (SD 0.9) and 17.5 (SD 1.1) years, respectively.</p>
            </fn>
            <fn id="table1fn4">
              <p><sup>d</sup>YEH: youth experiencing homelessness.</p>
            </fn>
            <fn id="table1fn5">
              <p><sup>e</sup>A total of 11 studies reported on mental illness, among which 6 reported on participants with psychiatric disorders and 5 on substance use.</p>
            </fn>
            <fn id="table1fn6">
              <p><sup>f</sup>PTSD: posttraumatic stress disorder.</p>
            </fn>
            <fn id="table1fn7">
              <p><sup>g</sup>ADHD: attention-deficit/hyperactivity disorder.</p>
            </fn>
          </table-wrap-foot>
        </table-wrap>
      </sec>
      <sec>
        <title>Study and Intervention Characteristics</title>
        <p>The study and intervention characteristics are summarized in <xref ref-type="table" rid="table2">Table 2</xref>. All studies were in preliminary phases; the majority (9/11, 82% studies or 10 reports) aimed to assess the feasibility of the intervention [<xref ref-type="bibr" rid="ref19">19</xref>,<xref ref-type="bibr" rid="ref38">38</xref>-<xref ref-type="bibr" rid="ref46">46</xref>], 3 studies explored preliminary results of efficacy [<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref47">47</xref>], and 2 studies described the development of the intervention [<xref ref-type="bibr" rid="ref39">39</xref>,<xref ref-type="bibr" rid="ref41">41</xref>]. Three studies (4 reports) were designed as randomized controlled trials (RCTs) [<xref ref-type="bibr" rid="ref38">38</xref>,<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref44">44</xref>,<xref ref-type="bibr" rid="ref45">45</xref>] but only reported feasibility or preliminary results of efficacy. The remaining studies (7/11, 64% studies) were experimental trials without randomization or were quasi-experimental studies [<xref ref-type="bibr" rid="ref19">19</xref>,<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref39">39</xref>-<xref ref-type="bibr" rid="ref41">41</xref>,<xref ref-type="bibr" rid="ref43">43</xref>,<xref ref-type="bibr" rid="ref46">46</xref>]. In terms of the intervention’s principal aim, 4 studies (5 reports) [<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref38">38</xref>,<xref ref-type="bibr" rid="ref39">39</xref>,<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref47">47</xref>] described interventions that were intended to reduce risky behaviors such as substance consumption (including tobacco, alcohol, and marijuana) and sexual risk behaviors, 3 interventions [<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref45">45</xref>,<xref ref-type="bibr" rid="ref46">46</xref>] focused on cognitive functioning, 3 interventions [<xref ref-type="bibr" rid="ref19">19</xref>,<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref43">43</xref>] aimed to provide emotional support or help with emotion regulation, 2 interventions [<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref42">42</xref>] provided information about access to health or other vital resources for YEH, and 1 intervention [<xref ref-type="bibr" rid="ref44">44</xref>] aimed to reduce anxiety and physiological stress.</p>
        <p>Intervention length varied greatly across the studies from 1 week to 8 months, and 2 studies offered a single-time use intervention [<xref ref-type="bibr" rid="ref41">41</xref>,<xref ref-type="bibr" rid="ref43">43</xref>]. Only 2 studies [<xref ref-type="bibr" rid="ref38">38</xref>,<xref ref-type="bibr" rid="ref45">45</xref>] included a follow-up period of 1 and 3 months. There was also great variation in dropout percentages from 14% to 81% among the 7 studies [<xref ref-type="bibr" rid="ref19">19</xref>,<xref ref-type="bibr" rid="ref38">38</xref>-<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref43">43</xref>,<xref ref-type="bibr" rid="ref45">45</xref>] that provided this information. From these studies, only 3 reported the reasons for dropout [<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref43">43</xref>,<xref ref-type="bibr" rid="ref45">45</xref>]; the most common reasons were loss of interest, discharges, scheduling conflicts, and change of address (<xref ref-type="table" rid="table3">Table 3</xref>).</p>
        <table-wrap position="float" id="table2">
          <label>Table 2</label>
          <caption>
            <p>Study and intervention characteristics organized by level of evidence.</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="150"/>
            <col width="160"/>
            <col width="160"/>
            <col width="0"/>
            <col width="160"/>
            <col width="170"/>
            <col width="200"/>
            <thead>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td colspan="3">Study characteristics</td>
                <td colspan="3">Intervention characteristics</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Design</td>
                <td>Study aim</td>
                <td colspan="2">Technology</td>
                <td>Features</td>
                <td>Intervention aim</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td>Thompson et al [<xref ref-type="bibr" rid="ref42">42</xref>], 2020</td>
                <td>RCT<sup>a</sup></td>
                <td>Feasibility and preliminary efficacy</td>
                <td colspan="2">Smartphone or mobile apps</td>
                <td>Daily tracker, in-person counseling, and resources information</td>
                <td>Reduce substance use and risky sexual behaviors</td>
              </tr>
              <tr valign="top">
                <td>Medalia et al [<xref ref-type="bibr" rid="ref45">45</xref>], 2017</td>
                <td>RCT</td>
                <td>Feasibility</td>
                <td colspan="2">Computer</td>
                <td>Computer exercises</td>
                <td>Training in neurocognition</td>
              </tr>
              <tr valign="top">
                <td>Linnemayr et al [<xref ref-type="bibr" rid="ref38">38</xref>], 2021</td>
                <td>Pilot RCT</td>
                <td>Feasibility</td>
                <td colspan="2">Mobile phone</td>
                <td>SMS text messages</td>
                <td>Quit smoking</td>
              </tr>
              <tr valign="top">
                <td>Tucker et al [<xref ref-type="bibr" rid="ref39">39</xref>], 2020</td>
                <td>Quasi-experimental</td>
                <td>Development feasibility</td>
                <td colspan="2">Mobile phone</td>
                <td>SMS text messages</td>
                <td>Quit smoking</td>
              </tr>
              <tr valign="top">
                <td>Chavez et al [<xref ref-type="bibr" rid="ref44">44</xref>], 2020</td>
                <td>Pilot RCT</td>
                <td>Feasibility</td>
                <td colspan="2">Oculus Go headset</td>
                <td>Virtual reality</td>
                <td>Reduce anxiety and physiological stress</td>
              </tr>
              <tr valign="top">
                <td>Schueller et al [<xref ref-type="bibr" rid="ref19">19</xref>], 2019</td>
                <td>Quasi-experimental</td>
                <td>Feasibility</td>
                <td colspan="2">Smartphone or mobile apps</td>
                <td>Push-in tips, daily tracker, phone calls, and SMS text messages</td>
                <td>Brief emotional support and coping skills</td>
              </tr>
              <tr valign="top">
                <td>Glover et al [<xref ref-type="bibr" rid="ref40">40</xref>], 2019</td>
                <td>Quasi-experimental</td>
                <td>Feasibility</td>
                <td colspan="2">Smartphone and mobile apps</td>
                <td>Push-in tips, daily tracker, hotline, text messages, automated systems, and resources information</td>
                <td>Mental health resources, emotional support, and brief cognitive behavioral interventions</td>
              </tr>
              <tr valign="top">
                <td>Leonard et al [<xref ref-type="bibr" rid="ref43">43</xref>], 2018</td>
                <td>Quasi-experimental</td>
                <td>Feasibility</td>
                <td colspan="2">Smartphone and mobile apps and wrist-worn sensor band</td>
                <td>Daily tracker, push-in tips, and self-report alert</td>
                <td>Emotion regulation (adolescent mothers)</td>
              </tr>
              <tr valign="top">
                <td>Sheoran et al [<xref ref-type="bibr" rid="ref41">41</xref>], 2016</td>
                <td>Quasi-experimental</td>
                <td>Development and feasibility</td>
                <td colspan="2">Smartphone and mobile apps</td>
                <td>Resources information</td>
                <td>Access to health and vital resources</td>
              </tr>
              <tr valign="top">
                <td>Chao et al [<xref ref-type="bibr" rid="ref36">36</xref>], 2017</td>
                <td>Quasi-experimental<sup>b</sup></td>
                <td>Efficacy</td>
                <td colspan="2">Smartphone and mobile apps</td>
                <td>Phone or video calls and push-in tips</td>
                <td>Reduce alcohol and substance use</td>
              </tr>
              <tr valign="top">
                <td>Karnik et al [<xref ref-type="bibr" rid="ref46">46</xref>], 2017</td>
                <td>Quasi-experimental<sup>c</sup></td>
                <td>Feasibility</td>
                <td colspan="2">Smartphone and mobile apps</td>
                <td>Phone calls and tracker</td>
                <td>Cognitive behavioral therapy</td>
              </tr>
              <tr valign="top">
                <td>Archie et al [<xref ref-type="bibr" rid="ref47">47</xref>], 2018</td>
                <td>Quasi-experimental<sup>c</sup></td>
                <td>Preliminary evidence on efficacy</td>
                <td colspan="2">Video game</td>
                <td>N/A<sup>d</sup></td>
                <td>Raise awareness of marijuana use</td>
              </tr>
            </tbody>
          </table>
          <table-wrap-foot>
            <fn id="table2fn1">
              <p><sup>a</sup>RCT: randomized controlled trial.</p>
            </fn>
            <fn id="table2fn2">
              <p><sup>b</sup>Poster.</p>
            </fn>
            <fn id="table2fn3">
              <p><sup>c</sup>Conference abstract.</p>
            </fn>
            <fn id="table2fn4">
              <p><sup>d</sup>N/A: not applicable.</p>
            </fn>
          </table-wrap-foot>
        </table-wrap>
        <table-wrap position="float" id="table3">
          <label>Table 3</label>
          <caption>
            <p>Participant engagement and retention strategies.</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="30"/>
            <col width="130"/>
            <col width="90"/>
            <col width="90"/>
            <col width="90"/>
            <col width="0"/>
            <col width="100"/>
            <col width="140"/>
            <col width="150"/>
            <col width="20"/>
            <col width="160"/>
            <thead>
              <tr valign="top">
                <td colspan="2">Intervention type, reference</td>
                <td>Participants, n</td>
                <td colspan="2">Intervention</td>
                <td colspan="2">Dropout<sup>a</sup>, n (%)</td>
                <td>Reported reasons to drop out</td>
                <td>Financial or material support</td>
                <td colspan="2">Access to the technology</td>
              </tr>
              <tr valign="top">
                <td colspan="2">
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>Duration</td>
                <td colspan="2">Follow-up</td>
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td colspan="2">
                  <break/>
                </td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td colspan="11">
                  <bold>Smartphone</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Thompson et al [<xref ref-type="bibr" rid="ref42">42</xref>], 2020</td>
                <td>60</td>
                <td>28 days</td>
                <td>N/A<sup>b</sup></td>
                <td colspan="2">20 (33)</td>
                <td>16 discharged; 1 incarcerated; 1 hospitalized; 1 self-withdrew; 1 relocated</td>
                <td colspan="2">US $25 to US $50 gift cards+smartphone or US $100 gift card</td>
                <td>Researchers provided the smartphones</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Schueller et al [<xref ref-type="bibr" rid="ref19">19</xref>], 2019</td>
                <td>35</td>
                <td>1 month</td>
                <td>N/A</td>
                <td colspan="2">15 (43)</td>
                <td>Unclear<sup>c</sup></td>
                <td colspan="2">Phone service and data</td>
                <td>Researchers provided the smartphones</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Glover et al [<xref ref-type="bibr" rid="ref40">40</xref>], 2019</td>
                <td>100</td>
                <td>6 months</td>
                <td>N/A</td>
                <td colspan="2">81 (81)</td>
                <td>Unclear</td>
                <td colspan="2">Smartphone+US $5 gift card</td>
                <td>Researchers provided the smartphones</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Sheoran et al [<xref ref-type="bibr" rid="ref41">41</xref>], 2016</td>
                <td>6</td>
                <td>One time</td>
                <td>N/A</td>
                <td colspan="2">N/A</td>
                <td>N/A</td>
                <td colspan="2">US $100 gift card</td>
                <td>Researchers provided the smartphones. A total of 83% (5/6) participants already owned a smartphone</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Chao et al [<xref ref-type="bibr" rid="ref36">36</xref>], 2017</td>
                <td>24</td>
                <td>1 month</td>
                <td>N/A</td>
                <td colspan="2">Unclear</td>
                <td>Unclear</td>
                <td colspan="2">Unclear</td>
                <td>Researchers provided the smartphones</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Karnik et al [<xref ref-type="bibr" rid="ref46">46</xref>], 2017</td>
                <td>20</td>
                <td>Unclear</td>
                <td>Unclear</td>
                <td colspan="2">N/A</td>
                <td>N/A</td>
                <td colspan="2">Unclear</td>
                <td>Researchers provided the smartphones</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Leonard et al [<xref ref-type="bibr" rid="ref43">43</xref>], 2018</td>
                <td>49</td>
                <td>Variable (6-8 months)</td>
                <td>N/A</td>
                <td colspan="2">9 (18)</td>
                <td>4 discharged; 4 technology problem; 1 did not use the ICT<sup>d</sup></td>
                <td colspan="2">US $90 stipend</td>
                <td>Researchers provided the smartphones</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Linnemayr et al [<xref ref-type="bibr" rid="ref38">38</xref>], 2021<sup>e</sup></td>
                <td>77</td>
                <td>6 weeks</td>
                <td>3 months</td>
                <td colspan="2">11 (14)</td>
                <td>Unclear</td>
                <td colspan="2">US $65</td>
                <td>Participants’ phone</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Tucker et al [<xref ref-type="bibr" rid="ref39">39</xref>], 2020<sup>e</sup></td>
                <td>28<sup>f</sup></td>
                <td>1 week</td>
                <td>N/A</td>
                <td colspan="2">2 (20)<sup>f</sup></td>
                <td>Unclear</td>
                <td colspan="2">Unclear</td>
                <td>Participants’ phone</td>
              </tr>
              <tr valign="top">
                <td colspan="11">
                  <bold>Other ICTs</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Medalia et al [<xref ref-type="bibr" rid="ref45">45</xref>], 2017</td>
                <td>91</td>
                <td>26 weeks</td>
                <td>1 month</td>
                <td colspan="2">69 (76)</td>
                <td>Baseline to week 26: 25 loss of interest; 14 moved; 17 scheduling conflict; 7 discharged; 4 withdrawn; 2 legal issues</td>
                <td colspan="2">Reimbursed for public transportation cost</td>
                <td>Researchers provided the computers</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Chavez et al [<xref ref-type="bibr" rid="ref44">44</xref>], 2020</td>
                <td>30</td>
                <td>One time</td>
                <td>1-3 days</td>
                <td colspan="2">1 (3)</td>
                <td>1 did not return</td>
                <td colspan="2">US $50</td>
                <td>Researchers provided the headset</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Archie et al [<xref ref-type="bibr" rid="ref47">47</xref>], 2018</td>
                <td>55</td>
                <td>Unclear</td>
                <td>Unclear</td>
                <td colspan="2">Unclear</td>
                <td>Unclear</td>
                <td colspan="2">Unclear</td>
                <td>Unclear</td>
              </tr>
            </tbody>
          </table>
          <table-wrap-foot>
            <fn id="table3fn1">
              <p><sup>a</sup>Percentage of dropouts: participants who were assessed at baseline and were lost to follow-up.</p>
            </fn>
            <fn id="table3fn2">
              <p><sup>b</sup>N/A: not applicable.</p>
            </fn>
            <fn id="table3fn3">
              <p><sup>c</sup>Unclear: authors did not provide sufficient or any information.</p>
            </fn>
            <fn id="table3fn4">
              <p><sup>d</sup>ICT: information and communication technology.</p>
            </fn>
            <fn id="table3fn5">
              <p><sup>e</sup>Linnemayr et al [<xref ref-type="bibr" rid="ref38">38</xref>] and Tucker et al [<xref ref-type="bibr" rid="ref39">39</xref>] reported the same population.</p>
            </fn>
            <fn id="table3fn6">
              <p><sup>f</sup>The sample that was analyzed in Tucker et al [<xref ref-type="bibr" rid="ref39">39</xref>] was included and analyzed in Linnemayr et al [<xref ref-type="bibr" rid="ref38">38</xref>]. Dropout percentage was calculated from the 10 participants who were included in the intervention, the rest (18 participants) participated in focus groups and were not counted for dropout proportions.</p>
            </fn>
          </table-wrap-foot>
        </table-wrap>
      </sec>
      <sec>
        <title>Technologies and Features</title>
        <p>As illustrated in <xref ref-type="table" rid="table2">Table 2</xref>, a total of 8 (9 reports) [<xref ref-type="bibr" rid="ref19">19</xref>,<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref38">38</xref>-<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref43">43</xref>,<xref ref-type="bibr" rid="ref45">45</xref>,<xref ref-type="bibr" rid="ref46">46</xref>] of the 11 studies provided e-mental health services, while the other 3 provided immersive guided meditation [<xref ref-type="bibr" rid="ref44">44</xref>], access to health and vital resources [<xref ref-type="bibr" rid="ref41">41</xref>], and educational content [<xref ref-type="bibr" rid="ref47">47</xref>]. Regarding the type of ICTs, the most common were mobile apps designed for YEH (7 studies [<xref ref-type="bibr" rid="ref19">19</xref>,<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref40">40</xref>-<xref ref-type="bibr" rid="ref43">43</xref>,<xref ref-type="bibr" rid="ref46">46</xref>]). Other ICTs include video games for educational purposes [<xref ref-type="bibr" rid="ref47">47</xref>], virtual reality for meditation [<xref ref-type="bibr" rid="ref44">44</xref>], and computer exercises [<xref ref-type="bibr" rid="ref45">45</xref>].</p>
        <p>Almost all the studies provided technology to the participants. Only 1 study (2 reports) [<xref ref-type="bibr" rid="ref38">38</xref>,<xref ref-type="bibr" rid="ref39">39</xref>] required that participants own a phone that could receive SMS text messages. In this regard, the authors reported that phone and smartphone ownership was very elevated among the targeted population, finding that approximately 83.6% (183/219) of the youth already contacted had a phone that could receive SMS text messages and more than half (60/77, 78%) of their population owned a smartphone, and participants reported having phone plans with unlimited minutes and texts (54/77, 70%). A study that offered a virtual reality experience [<xref ref-type="bibr" rid="ref44">44</xref>] reported that approximately 44% (8/18) of the participants under study had already used this technology in the past, and 100% (18/18) were interested in its future use.</p>
        <p>Among the 8 studies that presented interventions to deliver e-mental health services through ICTs, 6 [<xref ref-type="bibr" rid="ref19">19</xref>,<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref43">43</xref>,<xref ref-type="bibr" rid="ref46">46</xref>] combined e-mental health with mobile apps using the following features: trackers, push-in tips, automated systems to deliver support and brief cognitive behavioral interventions, or provided information about available resources for YEH. Five of these studies [<xref ref-type="bibr" rid="ref19">19</xref>,<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref46">46</xref>] also included sessions with a health provider or researcher (in person, phone or video calls, or text). One study (2 reports) in this category delivered e-mental health exclusively through SMS text messaging [<xref ref-type="bibr" rid="ref38">38</xref>,<xref ref-type="bibr" rid="ref39">39</xref>], and another study used computer exercises to deliver neurocognitive training [<xref ref-type="bibr" rid="ref45">45</xref>].</p>
      </sec>
      <sec>
        <title>Feasibility</title>
        <p>The feasibility of each intervention was assessed considering three main components [<xref ref-type="bibr" rid="ref34">34</xref>]: (1) acceptability of the interventions among participants, described as the perceived usefulness of the intervention and the intention of use; (2) implementation characterized here as the frequency of use and the failures or issues presented during the intervention; and (3) efficacy considering the positive or negative outcomes reported by each study. The results are presented in <xref ref-type="table" rid="table4">Table 4</xref>.</p>
        <p>In general, there was good acceptability of the use of ICT; the majority of studies (8/9, 89%) reported high or moderate to high ratings of participants’ evaluations regarding acceptability. Acceptability was rated according to the percentages of participants who reported high scores or gave good evaluations of the intervention (ie, high &#62;80%, moderate 30%-70%, and low &#60;30% of the participants).</p>
        <p>Regarding implementation, 6 studies (7 reports) [<xref ref-type="bibr" rid="ref19">19</xref>,<xref ref-type="bibr" rid="ref38">38</xref>-<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref43">43</xref>,<xref ref-type="bibr" rid="ref46">46</xref>] provided data about the frequency of use; only 1 study [<xref ref-type="bibr" rid="ref40">40</xref>] had moderate to low success, considering that a high number of participants dropped out (81%) of the intervention, while the rest reported moderate to high engagement. Frequency of use was rated considering the percentage of participants who completed &#62;90% of the intervention (ie, high &#62;90%, moderate 30%-80%, and low &#60;30% of the participants). Most issues reported by the authors were technical problems with the technology, such as the need to replace phones, problems with data services, and phone charging. A study that used virtual reality [<xref ref-type="bibr" rid="ref44">44</xref>] reported that some participants were concerned that the intervention may trigger seizures.</p>
        <p>Some studies have also explored intervention efficacy, and the results are summarized in <xref ref-type="table" rid="table4">Table 4</xref>. The most frequent positive outcomes were related to improvements in emotion regulation and stress management (4 studies) [<xref ref-type="bibr" rid="ref19">19</xref>,<xref ref-type="bibr" rid="ref43">43</xref>-<xref ref-type="bibr" rid="ref45">45</xref>]. This was followed by outcomes related to risky behaviors; 2 studies observed a decline in substance use [<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref42">42</xref>] and risky sexual behavior [<xref ref-type="bibr" rid="ref42">42</xref>], and 1 study [<xref ref-type="bibr" rid="ref47">47</xref>] reported greater knowledge of marijuana use and its potential risks through the use of an educational video game. In addition, a study [<xref ref-type="bibr" rid="ref45">45</xref>] found improvements in cognitive and psychological functioning after the use of computer exercises designed for neurocognition training, and another study [<xref ref-type="bibr" rid="ref19">19</xref>] reported small changes in symptoms of depression and posttraumatic stress disorder.</p>
        <p>Some studies [<xref ref-type="bibr" rid="ref38">38</xref>,<xref ref-type="bibr" rid="ref39">39</xref>,<xref ref-type="bibr" rid="ref43">43</xref>] included participants’ self-reports regarding the benefits of the interventions. For instance, participants mentioned that push notifications helped them better regulate their emotions [<xref ref-type="bibr" rid="ref43">43</xref>], and SMS text messages helped to overcome cravings [<xref ref-type="bibr" rid="ref38">38</xref>,<xref ref-type="bibr" rid="ref39">39</xref>].</p>
        <table-wrap position="float" id="table4">
          <label>Table 4</label>
          <caption>
            <p>Feasibility of the interventions including acceptability, implementation, and intervention efficacy.</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="30"/>
            <col width="240"/>
            <col width="0"/>
            <col width="150"/>
            <col width="160"/>
            <col width="220"/>
            <col width="200"/>
            <thead>
              <tr valign="top">
                <td colspan="3">Intervention type, reference</td>
                <td>Acceptability<sup>a</sup></td>
                <td colspan="2">Implementation<sup>b</sup></td>
                <td>Efficacy<sup>c</sup></td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>Frequency of use</td>
                <td>Issues</td>
                <td>
                  <break/>
                </td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td colspan="7">
                  <bold>Communication technologies</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Thompson et al [<xref ref-type="bibr" rid="ref42">42</xref>], 2020</td>
                <td colspan="2">High</td>
                <td>High</td>
                <td>In all, 33% (1/3) participants discontinued the use of the app</td>
                <td>The intervention group presented lower odds of drinking alcohol (OR<sup>d</sup>=0.14, 95% CI 0.03-0.64; <italic>P</italic>=.01) and having unprotected sex (OR=0.15, CI 0.03-0.85; <italic>P</italic>=.03) than the treatment as usual group, but no significant difference for use of marijuana (OR=0.39, CI 0.07-2.33; <italic>P</italic>=.30).</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Schueller et al [<xref ref-type="bibr" rid="ref19">19</xref>], 2019</td>
                <td colspan="2">Moderate to high</td>
                <td>Moderate to high</td>
                <td>Mobile service provider, phone replacement, and exceeding the data limit</td>
                <td>Very little improvements in clinical outcomes with small effect sizes for symptoms of depression (Cohen <italic>d</italic>=0.27), posttraumatic stress disorder (Cohen <italic>d</italic>=0.17), and emotion regulation (Cohen <italic>d</italic>=0.10); all <italic>P</italic>&#62;.50.</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Glover et al [<xref ref-type="bibr" rid="ref40">40</xref>], 2019</td>
                <td colspan="2">High</td>
                <td>Moderate to low</td>
                <td>23% (23/100) phone replacement</td>
                <td>Unavailable</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Sheoran et al [<xref ref-type="bibr" rid="ref41">41</xref>], 2016</td>
                <td colspan="2">High</td>
                <td>Unavailable</td>
                <td>Details unavailable</td>
                <td>Unavailable</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Chao et al [<xref ref-type="bibr" rid="ref36">36</xref>], 2017</td>
                <td colspan="2">Unavailable</td>
                <td>Unavailable</td>
                <td>Details unavailable</td>
                <td>Intervention group showed significantly reduced use of marijuana (<italic>P</italic>&#60;.05 ;from Chao et al [<xref ref-type="bibr" rid="ref36">36</xref>]—poster)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Karnik et al [<xref ref-type="bibr" rid="ref46">46</xref>], 2017</td>
                <td colspan="2">High</td>
                <td>High</td>
                <td>Phone replacement</td>
                <td>Unavailable</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Leonard et al [<xref ref-type="bibr" rid="ref43">43</xref>], 2018</td>
                <td colspan="2">High</td>
                <td>Moderate to high</td>
                <td>Technical</td>
                <td>Unavailable<sup>e</sup></td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Leonard et al [<xref ref-type="bibr" rid="ref43">43</xref>], 2018</td>
                <td colspan="2">Moderate</td>
                <td>Moderate</td>
                <td>Phone charging and social issues (embarrassment)</td>
                <td>Unavailable<sup>e</sup></td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Linnemayr et al<sup>f</sup> [<xref ref-type="bibr" rid="ref38">38</xref>], 2021</td>
                <td colspan="2">High</td>
                <td>Moderate</td>
                <td>Changed phone number, phone stolen, and bad reception</td>
                <td>Unavailable</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Tucker et al<sup>f</sup> [<xref ref-type="bibr" rid="ref39">39</xref>], 2020</td>
                <td colspan="2">Moderate to high</td>
                <td>High</td>
                <td>Keeping the phone charged</td>
                <td>Unavailable</td>
              </tr>
              <tr valign="top">
                <td colspan="7">
                  <bold>Other information and communication technologies</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Medalia et al [<xref ref-type="bibr" rid="ref45">45</xref>], 2017</td>
                <td colspan="2">Unavailable</td>
                <td>Unavailable</td>
                <td>Sessions took longer than expected</td>
                <td>Significant effect on cognitive (verbal memory: <italic>F</italic><sub>2,89</sub>=20.28; <italic>P</italic>&#60;.0001), processing speed (<italic>F</italic><sub>2,89</sub>=9.35; <italic>P</italic>=.0002), executive functioning (<italic>F</italic><sub>2,89</sub>=22.26; <italic>P</italic>&#60;.0001), attention (<italic>F</italic><sub>2,89</sub>=3.67; <italic>P</italic>=.03), global cognition (<italic>F</italic><sub>2,89</sub>=39.89; <italic>P</italic>&#60;.0001), and psychological functioning (<italic>F</italic><sub>2,89</sub>=11.21; <italic>P</italic>&#60;.00001)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Chavez et al [<xref ref-type="bibr" rid="ref44">44</xref>], 2020</td>
                <td colspan="2">High</td>
                <td>Unavailable</td>
                <td>Trigger seizures concern</td>
                <td>No significant differences for anxiety or salivary cortisol measures between intervention (virtual reality meditation) and other groups (audio meditation and virtual reality imagery).</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Archie et al [<xref ref-type="bibr" rid="ref47">47</xref>], 2018</td>
                <td colspan="2">High</td>
                <td>Unavailable</td>
                <td>Unavailable</td>
                <td>Intervention group obtained significantly greater mean scores on knowledge about cannabis use and harms and psychosis (mean 6.8, SD 1.6 and 5.5, SD 1.9, respectively; <italic>P</italic>&#60;.05)</td>
              </tr>
            </tbody>
          </table>
          <table-wrap-foot>
            <fn id="table4fn1">
              <p><sup>a</sup>Acceptability as perceived usefulness of the intervention by youth and their practitioners, intention to use the technology—high: &#62;80% of participants rated it with a high score or good evaluation; moderate: 30% to 70% of participants rated it with high scores or good evaluation; low: &#60;30% of participants rated it with a high score or good evaluation.</p>
            </fn>
            <fn id="table4fn2">
              <p><sup>b</sup>Implementation or feasibility framework: degree of success or failure of execution, amount and type of resources, and factors affecting implementation ease or difficulty. The feasibility study framework by Bowen et al [<xref ref-type="bibr" rid="ref34">34</xref>]—high: &#62;90% of allocated participants completed all or &#62;90% of the sessions; moderate: 30% to 90% of allocated participants completed all or &#62;90% of the sessions; &#60;30% of allocated participants completed all or &#62;90% of the sessions.</p>
            </fn>
            <fn id="table4fn3">
              <p><sup>c</sup>Positive or negative outcomes tendency as reported by authors, statistically significant or not.</p>
            </fn>
            <fn id="table4fn4">
              <p><sup>d</sup>OR: odds ratio.</p>
            </fn>
            <fn id="table4fn5">
              <p><sup>e</sup>On the basis of qualitative methods the study reported that the participants perceived the app helpful in identifying and regulating emotions, and managing stress.</p>
            </fn>
            <fn id="table4fn6">
              <p><sup>f</sup>Linnemayr et al [<xref ref-type="bibr" rid="ref38">38</xref>] and Tucker et al [<xref ref-type="bibr" rid="ref39">39</xref>] reported the same population.</p>
            </fn>
          </table-wrap-foot>
        </table-wrap>
      </sec>
      <sec>
        <title>Quality Appraisal</title>
        <p>Four randomized controlled studies [<xref ref-type="bibr" rid="ref38">38</xref>,<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref44">44</xref>,<xref ref-type="bibr" rid="ref45">45</xref>] were included in the quality appraisal (<xref ref-type="supplementary-material" rid="app2">Multimedia Appendix 2</xref> [<xref ref-type="bibr" rid="ref19">19</xref>,<xref ref-type="bibr" rid="ref38">38</xref>-<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref42">42</xref>-<xref ref-type="bibr" rid="ref45">45</xref>]). Although the authors reported some results about the efficacy of the intervention, all of them were principally interested in the feasibility of the intervention. As a general overview, the main methodological issues were the lack of blindness and a lack of clarity on treatment allocation concealment and the follow-up of dropouts.</p>
        <p>In addition, 4 nonrandomized experimental studies (quasi-experimental) were assessed for quality. However, only 2 [<xref ref-type="bibr" rid="ref19">19</xref>,<xref ref-type="bibr" rid="ref43">43</xref>] of them reported the effects of the interventions, while the other 2 [<xref ref-type="bibr" rid="ref39">39</xref>,<xref ref-type="bibr" rid="ref40">40</xref>] focused on feasibility. None of these studies provided a control group, and only 1 study provided information about the absence of coexisting treatments that may interfere with the cause-effect relationship. Finally, only 2 studies adequately described their follow-up, with no reported patterns of loss to follow-up (<xref ref-type="supplementary-material" rid="app2">Multimedia Appendix 2</xref>).</p>
      </sec>
    </sec>
    <sec sec-type="discussion">
      <title>Discussion</title>
      <sec>
        <title>Principal Findings</title>
        <p>This scoping review is the second in a series of reviews that we conducted at the intersections of health, technology, and YEH. We found a small number of studies conducted in even fewer cities within North America, indicating the limited research attention globally on the use of technology to deliver mental health services to YEH. This is rather concerning given that youth represent a significant part of the homeless population and that previous research indicates their high access to and use of technology for day-to-day needs, cumulatively indicating a largely unaddressed area of research and practice. Moreover, the geographical settings of the studies were unclear in some of the reviewed reports. For future research, we recommend more specific documentation regarding the location of the study to allow consideration of the role of contextual factors in relation to the results. Regarding the level of evidence, the studies included in this review were mostly pilot and feasibility studies, which were carried out to establish the preliminary planning of a full-size RCT and did not contribute to the assessment of the effectiveness and efficacy of the intervention [<xref ref-type="bibr" rid="ref48">48</xref>]. According to the studies that provided sociodemographic information, the largest ethnicity was Black and African American; gender distribution was relatively balanced with a small representation of transgender and gender fluid individuals; and a small proportion of participants reported being homosexual, bisexual, or other. However, it is important to note that not all studies reported sufficient details regarding sample characteristics; for example, the mean age was not always reported, and only a few studies specified participants’ gender and sexuality. Moreover, the participants were not always characterized in terms of mental illness or condition.</p>
        <p>The high levels of acceptability and success of implementation reported in these studies indicate that the use of ICTs to provide mental health services to YEH has the potential to be a feasible approach and warrants further research. Concurrently, although technology may support the delivery of mental health services, the use of a single app is unlikely to yield long-lasting results, especially considering that homelessness is a multifactorial problem. It is important to combine ICTs with traditional support and treatment services, which include the active participation of health care providers, as seen in certain studies [<xref ref-type="bibr" rid="ref19">19</xref>,<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref43">43</xref>,<xref ref-type="bibr" rid="ref46">46</xref>]. This is consistent with previous literature, highlighting the need for ICTs to be implemented as cointerventions [<xref ref-type="bibr" rid="ref26">26</xref>].</p>
        <p>The most notable finding was that smartphones were the preferred type of ICT and were mostly used to offer services via mobile apps. Push notifications were particularly liked by YEH [<xref ref-type="bibr" rid="ref19">19</xref>,<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref43">43</xref>], suggesting that alerts and reminders in real time may be a promising way to engage and interact with YEH. Although a study concluded that SMS text messages also had high levels of acceptability [<xref ref-type="bibr" rid="ref39">39</xref>], authors reported that during the first phase of the intervention, some participants did not appreciate the formality of the texts and described them as “mechanical” [<xref ref-type="bibr" rid="ref39">39</xref>]. The authors then decided to make some changes to their SMS text messaging approach in the second phase of their research and found that participants preferred a light tone associated with the messaging; for example, with fun elements such as emojis and memes [<xref ref-type="bibr" rid="ref38">38</xref>]. Daily trackers were another well-liked feature. The authors described this as helpful and beneficial for YEH [<xref ref-type="bibr" rid="ref19">19</xref>,<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref43">43</xref>]. This may be because of the ability of these tools to provide structure in daily life, which may contribute to a sense of empowerment and support. This aligns with the importance of providing self-management support to homeless people affected by chronic diseases [<xref ref-type="bibr" rid="ref49">49</xref>]. Mobile technology increases access to multiple resources, which not only facilitates self-management but also responds to social needs [<xref ref-type="bibr" rid="ref50">50</xref>]. Therefore, it is possible that smartphones and mobile apps, especially those that include reminders and daily trackers, have the potential to increase YEH outreach and engagement.</p>
        <p>We also found emerging uses of 2 other types of technology in this population: virtual reality [<xref ref-type="bibr" rid="ref44">44</xref>] and video games [<xref ref-type="bibr" rid="ref47">47</xref>]. Despite the positive outcomes of these studies, the samples were small, and the interventions were in the early stages of development; thus, further research is needed to deepen our understanding of their feasibility and impact. Computer exercises for cognitive development were assessed in only 1 study [<xref ref-type="bibr" rid="ref45">45</xref>], which indicated that the completion rate was particularly low, which may reflect how YEH’s challenging situation hinders their participation in programs that require their physical presence.</p>
        <p>Overall, the findings from this review contribute to the broader literature situated at the intersections of homeless youth and technology access and use, which shows that youth use the internet, social media, and mobile technologies at high rates and for various social, informational, and daily needs [<xref ref-type="bibr" rid="ref20">20</xref>,<xref ref-type="bibr" rid="ref51">51</xref>]. Cumulatively, these findings indicate the importance of advancing the use of technology in research conducted with YEH as well as delivering mental health–related information and services to this population. More research is needed to better understand the use of technology to deliver mental health services to YEH as an adjunct to care for complementing face-to-face interventions or as stand-alone interventions and services.</p>
        <p>Concurrently, it is important to note that this review also found several challenges encountered by the authors that pertain to technology that needs to be considered by practitioners and researchers embarking on this field. Issues pertain to access to wireless internet, battery life, and locations to charge batteries; hence, strategies to ensure technology availability and to guarantee access to the internet should be designed a priori. Moreover, limited attention was given to privacy and security, although confidentiality was a concern for some participants [<xref ref-type="bibr" rid="ref41">41</xref>,<xref ref-type="bibr" rid="ref43">43</xref>], and only 1 study [<xref ref-type="bibr" rid="ref43">43</xref>] reported some information about observed adverse effects (embarrassment as a social issue). Future research should consider the potential risks and unfavorable effects of YEH [<xref ref-type="bibr" rid="ref20">20</xref>]. Finally, according to our results and as suggested in previous systematic reviews [<xref ref-type="bibr" rid="ref26">26</xref>], future research must consider looking beyond feasibility and start testing the effectiveness of ICT interventions in larger samples in terms of their ability to respond to the urgency of improving mental health care access and quality for YEH.</p>
        <p>Finally, future research and practice in this area should consider including YEH more actively within the design, development, and evaluation of technology-enabled mental health interventions targeting YEH. This goes beyond including YEH as participants in usability studies and interviews or as employees to promote projects but more actively as research collaborators and partners (and the related challenges in this regard).</p>
      </sec>
      <sec>
        <title>Limitations of the Study</title>
        <p>Despite the rigor of our methodology and the literature search, our results should be interpreted cautiously. First, this was a scoping review that only included 11 studies (12 reports), among which 3 were conference abstracts and posters, which provided limited information. Our results may be biased by the elevated percentages of dropouts [<xref ref-type="bibr" rid="ref19">19</xref>,<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref45">45</xref>] (43%, 81%, 33%, and 76%, respectively), and only a few studies have reported the reasons for dropout. Hence, it should be acknowledged that our results regarding acceptability and success of implementation levels may be overestimated if dropout percentages were mostly represented by participants who were dissatisfied with the interventions. The participants included in the RCT studies were not blinded to the interventions, which may have affected their perceptions, especially if they compared themselves with the control groups. All studies were published in the United States (Chicago, New York, Los Angeles, Oakland, and other nonspecified cities located in the northeast and midwestern states) and Canada, suggesting that our results may only be applicable to North America or in countries where the availability of high technology devices is more common and potentially also to urban areas with high rates of homelessness. In addition, few studies have reported the effectiveness of their intervention; therefore, we cannot provide any conclusions on this aspect.</p>
      </sec>
      <sec>
        <title>Conclusions</title>
        <p>This scoping review synthesizes the current literature on the use of technology to provide mental health services to the YEH. These results are encouraging in terms of acceptability, suggesting that ICTs are promising tools to leverage in the delivery of mental health services to the YEH. We expect an increase in the use of ICTs in the coming years. Moreover, owing to the current COVID-19 pandemic and restrictive measures, an increase in mental health care needs among YEH may be observed, highlighting the importance of novel methods to reach and engage this population.</p>
      </sec>
    </sec>
  </body>
  <back>
    <app-group>
      <supplementary-material id="app1">
        <label>Multimedia Appendix 1</label>
        <p>PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews) checklist.</p>
        <media xlink:href="jmir_v25i1e41939_app1.pdf" xlink:title="PDF File  (Adobe PDF File), 497 KB"/>
      </supplementary-material>
      <supplementary-material id="app2">
        <label>Multimedia Appendix 2</label>
        <p>Quality appraisal tables.</p>
        <media xlink:href="jmir_v25i1e41939_app2.pdf" xlink:title="PDF File  (Adobe PDF File), 72 KB"/>
      </supplementary-material>
    </app-group>
    <glossary>
      <title>Abbreviations</title>
      <def-list>
        <def-item>
          <term id="abb1">ICT</term>
          <def>
            <p>information and communication technology</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb2">PRISMA</term>
          <def>
            <p>Preferred Reporting Items for Systematic Reviews and Meta-Analyses</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb3">PRISMA-ScR</term>
          <def>
            <p>Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb4">RCT</term>
          <def>
            <p>randomized controlled trial</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb5">YEH</term>
          <def>
            <p>youth experiencing homelessness</p>
          </def>
        </def-item>
      </def-list>
    </glossary>
    <notes>
      <sec>
        <title>Data Availability</title>
        <p>Data sharing was not applicable to this paper, as all data were obtained from publicly available reports. The extracted data from these reports are presented in tables within the manuscript.</p>
      </sec>
    </notes>
    <ack>
      <p>The authors would like to acknowledge the support of Myrian Grondin, who assisted in developing and implementing the search strategy.</p>
    </ack>
    <fn-group>
      <fn fn-type="con">
        <p>All the authors contributed substantially to the content and approved the final version of the manuscript. SL conceived the original idea, main objectives, methodology, and supervised the project. SE and VS implemented the protocol in close consultation with SL as part of course credits toward a professional degree in occupational therapy and wrote a preliminary version of the report. RP and SL contributed to the validation and interpretation of the results and then developed the report into a manuscript with significant contributions. All the authors have commented on the final version of the manuscript.</p>
      </fn>
      <fn fn-type="conflict">
        <p>None declared.</p>
      </fn>
    </fn-group>
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