Health care education includes preregistration education, postregistration education, and lifelong learning for practicing clinicians [1]. The goal of health care professions education is to improve the potential of people—doctors, nurses, and allied health care professionals—to meet the health needs of patients, communities, and populations [2]. This requires ensuring that students learn what they need to know and be able to do, assessing the extent to which educational goals and outcomes are achieved and monitoring the quality of educational programs [1].

Digital education can be defined as learning through the use of electronic technology. It is becoming increasingly popular in academic and clinical settings [3] for continuing education [4]. Although education has evolved from an offline to a web-based environment through internet access, the COVID-19 pandemic has made web-based learning the standard delivery method worldwide [5,6]. Thus, the new normal educational practices based on technology-enabled globalization, borderless teaching, and seamless learning are emerging [7]. The transition from an in-person learning format to a digital learning format brings new challenges [8] but also opens new opportunities for educators through the use of a digital education platform. Digital education platforms are web-based systems that automate the administration of learning activities, including delivery, tracking, and reporting activities [9]. They subsequently generate substantial amounts of data on student learning, which are available for further analysis with learning analytics (LA).

LA can be defined as the “measurement, collection, analysis, and reporting of data about learners and their contexts, for purposes of understanding and optimizing learning and the environments in which it occurs” [10]. LA refers to the collection and analysis of data from digital education platforms. Data analysis is used to determine student engagement in various digital learning activities to improve student learning. Specifically, LA differs from traditional educational analyses in 3 ways. First, data sets are typically much larger because of the strong quantitative focus, allowing for a higher degree of confidence in the generalizability of the results [11]. Second, data collected through technology has a finer granularity of variables than those collected via self-report, interview, or observational data [12]. Finally, the data are usually longitudinal [11], meaning that the methods and processes used to collect the data can incorporate a temporal dimension into the analysis [13]. These features provide opportunities for new insights by allowing learners to record, analyze, and retrieve their learning processes and outcomes for future use [14].

Given that LA provides powerful mechanisms for understanding, interpreting, and shaping learning processes and experiences using data-driven methods, research in this field has gained popularity since its inception as a scientific discipline in 2011 [15]. The number of studies using the keyword learning analytics in SciVerse Scopus between 2011 and 2021 was initially in the 2-digit range (n=29) but has since steadily increased, peaking at 917 in 2019. Despite a minor decline in the past 2 years (n=911 in 2020 and n=825 in 2021), the area continues to generate sizable interest.

Although many studies have been conducted in the last decade that demonstrate the usefulness of LA for health care professions education, we have been able to identify only 2 reviews on this topic [14,16]. Their limitations were that both covered literature reviews only up to 2017, and one of the reviews included data from a single database (ie, MEDLINE). Moreover, they did not propose any framework to analyze the reviewed literature. On the basis of our literature review, which included papers from 10 databases, we identified 4 components of LA. Those 4 components were conceptualized in the form of a life cycle. The life cycle is a cyclical process that explains, in 4 stages, what digital learning content is created, what data are gathered from the content, and how the data are analyzed and used to achieve learning purposes. The first stage of the life cycle involves the creation of learning content. The content could be an assessment or some other type of digital material. The gathering of data occurs in the second stage. It entails gathering data from various sources, such as learners’ interactions with digital learning content and their performance on assessments and tests. This can be as simple as mouse clicks or key presses or as complex as time spent on different pages or interaction with videos or audio files. The interaction with the material generates data that can be analyzed using analytics tools in the third stage of the life cycle. Finally, in the fourth stage of the life cycle, the data analysis results would be used to help improve learner performance, the quality of learning experience, or both.

The idea of an LA life cycle is not new and was previously discussed in a study by Clow [17]. The study proposed a 4-step LA model that includes learners, data, metrics, and interventions. On the basis of the model, learners are people who learn, data are what we collect about learner behavior, metrics are numbers or statistics that describe data, and interventions are specific programs or sets of steps to provide learners with support in an area of need. Although our proposed life cycle model shared some similarities with Clow’s model, the main difference between the 2 models is that the first stage of our LA life cycle is referred to as content and not learner. We choose to exclude learner from our life cycle because previous research has shown that LA is highly content dependent [18]. When designing a course, it is critical to spell out content curation (the totality of what is to be taught in a course). It forms the basis for teaching by determining which topics, concepts, facts, skills, and values are expected to be taught and learned. With a deep dive into what goes into teaching and learning, we can make an informed decision about what variables and metrics can be tracked and analyzed to reveal learners’ preferences and engagement. In other words, content has implications for what data are collected, how such data need to be preprocessed, what approaches can be applied to analyze data, and what can be done to optimize learning outcomes. The research questions that guided this review were as follows:

We searched the following databases for papers written in English from January 2010 to October 2021: MEDLINE, Embase, Web of Science, ERIC, Cochrane Library, PsycINFO, CINAHL, ICTP, Scopus, and IEEE Explore. The year 2010 was used as the starting point for our search, as the field of LA was formally recognized after the first International Conference on LA and Knowledge in 2011 [20]. We developed an initial search strategy based on a past publication on digital health education [21]. After initial title and abstract screening, we used the Search Refiner and Word Frequency Analyzer tools [22] to refine our search strategy further. Finally, we incorporated terms denoting different digital education platforms seen in the initially screened literature (Table S1 in Multimedia Appendix 1). Our final search strategy comprised (1) terms denoting health care professionals, (2) terms denoting different web-based learning environments, and (3) terms relating to LA. Multimedia Appendix 2 contains the final search strategies for all databases.

We included peer-reviewed publications that met the following criteria: papers on health care professions education, papers on digital education, and papers that collected LA data. We excluded papers that collected data about patient education; educators and not learners; and multimodal LA, abstracts, presentations, reviews, and commentary columns and papers where full texts could not be obtained (Textbox 1).

In total, 2 reviewers (IB and MM) performed title, abstract, and full-text screening of all publications retrieved using the first version of our search strategy. After the first round of screening, they defined a detailed set of inclusion and exclusion criteria and clearly explained the defined criteria to the other 4 reviewers (AP, CD, WLT, and CSA). All 6 reviewers worked in pairs sequentially and evaluated all retrieved papers using our final search strategy. We resolved disagreements on study selection by consensus and discussion with other reviewers.

A total of 3 reviewers (IB, MM, and CSA) collaborated on a data charting form to select the variables to be extracted. In an iterative process, the 3 reviewers separately charted the data, reviewed the findings, and modified the data extraction form. The 3 reviewers then grouped study data by type of digital education content, type of data obtained from student interactions with digital education platforms, analytics approaches used to process the collected data, and finally the purposes of the LA. We resolved disagreements on data extraction by consensus and discussion with other reviewers. Upon the completion of data extraction, the data were collated, summarized, and subsequently organized into groups according to similarities and differences. Tentative codes were added to these groups and iteratively discussed and revised to generate a comprehensive map of terms. The map was then used to conduct a narrative synthesis, which allowed for the identification of key themes and patterns within the data.

Among the included papers, the number of articles showed an upward inclination over the last decade, reaching a relative maximum in 2020 (n=14) and declining in 2021 (n=7). The most common study locations were the United States (n=12), Australia (n=11), Saudi Arabia (n=10), and Spain (n=6). Other countries had ≤5 papers, and 2 papers did not report the study location. A total of 60 studies were conducted in a university context with undergraduate and postgraduate students, and the remaining studies recruited health care professionals. The most common subject areas were medicine (n=32), dentistry (n=8), and nursing (n=7). Moodle [23] was the most commonly used digital education platform among the included articles (n=29), followed by Blackboard (n=4) [24,25]. A summary of article characteristics is shown in Table S2 in Multimedia Appendix 1.

In our literature analysis, we identified several components of the LA process. We propose that these components can be conceptualized as part of a larger LA life cycle. Figure 2 shows the life cycle of LA, starting from digital education content creation, followed by the data collection process, the use of analytics to process the collected data, and finally the purposes for which LA was used. Digital education content is mostly created by educators to support student learning, but in certain cases, it can also be created by learners’ peers (eg, discussion forum materials). While students are interacting with the provided digital education content, data on their use are collected and stored for further processing. The raw data include the click-level data that contain time-stamped information about every interaction with the digital education platform. The preprocessed data refer to the data that are mostly aggregated and shown in a dashboard. Both types of data can be used later in the process of analyzing the data. We identified 5 types of analytical approaches: (1) descriptive statistics, (2) inferential statistics, (3) data visualization, (4) machine learning, and (5) social network analysis. Finally, as stated in the definition of LA itself [10], the purpose of LA is to “understand and optimize learning and the environments in which it occurs.” Once the entire process of collecting and analyzing data is complete, the knowledge gained can be used to improve the produced digital education content, which then starts a new round of the entire LA life cycle.

Education content is any material that can be used to facilitate the learning process. Currently, many types of content are available for various learning purposes. Exploring the various types of content used in health care professions education is essential for understanding the contextual complexity that shapes the way we can build and use LA. The contents of the various studies examined in this review can be classified into 4 broad categories: (1) static materials, (2) dynamic materials or multimedia, (3) discussion forum materials, and (4) assessment materials (Table S3 in Multimedia Appendix 1). A total of 62% (40/65) of studies reported 1 or 2 types of digital education content [3,24,26-63], 28% (18/65) of studies reported 3 types [25,64-80], and the remaining 11% (7/65) of studies reported all 4 types [81-87].

Static materials are any type of digital education content that does not contain interactive elements. These include articles [81], guidelines [25], class notes [64], websites [26], case descriptions [27], glossaries of terms [28], images [65], slide decks [66], and books [82]. A total of 45% (29/65) of papers discussed providing static materials and outlining what specific materials were available for learners to view or read [25-29,42,58,60,61,63-70,72-74,76-78,80-82,84-86]. Another 9% (6/65) of studies used static materials but did not specify what materials were prepared for learners [36,44,75,79,83,87]. Among the various options, class notes appeared to be the most popular static material. Static materials remained popular because they can be easily viewed on any browser or mobile device and do not require additional plug-ins or technology [29].

Dynamic materials or multimedia are types of content that combine visual (eg, images, text, and animations) and auditory materials (eg, audio and podcast) in a single content package to convey a message [30]. Typically, they consist of animations [68], videos [69], and lecture recordings [31]. These materials were found to be the second most popular format and were discussed in 49% (32/65) of papers [24-26,30-35, 46,47,52,56,57,64-71,74,76-78,80-82,84-86]. A total of 8% (5/65) of other studies did not specify which dynamic materials they had prepared for their learners [41,44,79,83,87]. Although videos remained the primary form of instruction in health care professions education, some studies have highlighted the importance of experiential learning [32]. A few studies have examined a computer program [33] or application software [71] with interactive controls and activities that provide learners with some level of control to create a sense of authenticity, immersion, and interaction. This would allow learners to contextualize theoretical knowledge in a simulated environment by linking new experiences to prior knowledge. This type of content is an excellent solution for training in health care professions in a safe environment without fear of distressing the patient [34]. Undeniably, dynamic materials or multimedia are more versatile and promise greater engagement in learning than static text or images alone [35].

Discussion forum materials are provided to conduct specific learning activities outside the classroom, which are structured by educators [36]. The discussion forum is one of the most important social elements in a digital education course [3]. It is an effective tool to transform the classroom into a networked learning environment [86]. Students can actively engage in their learning process and develop important communication skills while posting, commenting, liking, and collaborating with other students on course content [83]. In total, 35% (23/65) of papers presented the use of a discussion forum to support student learning, although the materials used in the papers were not specified [3,36-38,48-51,54,59,62,64,71-73,75,81-87]. Understandably, each forum has its own set of category-based threads that are visible to all the learners in a course. These threads or posts create an active learning environment in which students regularly reflect on course content and actively collaborate to build knowledge through discussion. As discussion forums are asynchronous, they provide a safe environment for students to share ideas and learn from each other [73].

Assessment materials were the most popular digital education content, with 72% (47/65) of papers discussing them [24,25,27-30,32-35,39-43,45,46,52,53,55,56,58,60,61,65-87]. Assessment materials are important for improving the overall quality of learning. Learners’ perceptions of when, how, and what they are assessed on affect how they learn. Assessment materials include drag and drop, fill in the blanks, true or false [81], matching, freehand drawing, labeling [68,74], flash cards [35,40], quizzes [75], multiple-choice questions (MCQs) [84], problem-based learning [85], practical tests [39], assignments [84], short answers [86], and essays [41]. Most assessment materials were administered at the end of a module or course so that educators could determine how much students have learned and retained and whether learning objectives have been met [4,25]. Of the 47 papers, 32 (68%) papers indicated that their assessment materials included feedback to help learners gain a better understanding of a topic and provide them with a reflection prompt [25,27,28,30,32-34,42,43,53,55,58,60,61 ,65-68,70-72,74,76,77,79-81,83-87]. Furthermore, assessment materials were also a fun and interactive way to create natural breaks between main topics and make learners feel like the course is progressing [65]. Although gamified assessments are possible, only 1 study has investigated this [43]. Students were found to be more motivated in the assessments when such features were effectively integrated.

Data collected from the digital education platform can be broadly divided into 2 categories: raw and preprocessed data. Raw data consist of unprocessed data taken directly from the platform often in the form of log files. Many platforms automatically generate log files as a record of all user interactions with the system. For instance, the Moodle platform maintains a log of all user actions on the system and the time they were made (Figure 3). Preprocessed data can then be obtained by processing the raw data and aggregating data points to focus on a specific aspect of it. For example, the same log data can be used to determine how often a student viewed a given course by extracting each instance of a specific user accessing that course. We found that most preprocessed data types fit into the broader categories of (1) number of connections, (2) time spent, and (3) forum interactions (Table S4 in Multimedia Appendix 1). Moreover, not all raw data consist of log files. Other types of raw data can be collected directly from relevant learning materials on the digital education platform, which we categorized into (4) test scores and (5) textual data.

A number of connections refers to data that measures the number of times users connect to the digital education platform. This is one of the most common data types collected in LA research and can be derived from log data from many platforms. Of articles that collected data on the number of connections to the platform, 32% (21/65) of collected data on multiple content types individually [24,26,27,29,36,37,39,56,58,63-65,67, 73,76,78-80,82,85,86]. This allows for more detailed results by comparing the use of different digital education content types with student outcomes. Furthermore, 12% (8/65) of papers counted only the total, aggregated number of connections to the platform, without further dividing by content type [30,44,45,52,74,75,77,83], whereas 71% (25/65) of articles focused on connections to just 1 content type, such as in a study by Corrias and Cho [46], which measured student access to only the web-based video content [25,28,31,33,35,38, 40,42,43,46-51,54,55,57,59,61,62,68-70,72]. A total of 26% (17/65) of papers used log data to generate timeline analytics, deriving insights into the distribution of connections over a day, week, semester, or even school year [31,33,39-43, 47,53,55,57,65,68,70,71,75,86]. In so doing, researchers could determine the times at which materials were most frequently accessed and identify potential patterns, such as the relationship between material use and examination dates or the material access behaviors of higher-performing students.

Time spent measures the amount of time that users spend on the digital education platform. One way in which these data can be used is to understand how students interact with learning materials. For example, Cirigliano et al [65] measured the number of times students spent learning on each series of learning cards. They were able to distinguish between 3 types of student card interactions: those where students spent <20 seconds per card (rushing), those where they spent >100 seconds per card (idling), and those where they spent 20 to 100 seconds. Gaining a better understanding of rushing and idling can provide insights into whether students truly engage in digital education content. As with the number of connections, only 3% (2/65) of papers specified the amount of time spent on each content type [65,71], whereas 3% (2/65) of others calculated the overall time spent on the digital education platform [47,75]. The remaining (13/65, 20%) reviewed papers examined connections to only 1 content type [31,33,39-43,53,55,57,68,70,86].

Forum interactions consist of data derived from the students’ use of web-based forums [3,37,38,48-51,54,59,62,64]. The data collected typically included the IDs of the sender and receiver, the times that the post was written and modified, the post’s content, and the thread and forum where it was written. A total of 5% (3/65) of articles used forum interactions to observe how students engaged in problem-based learning that involved discussing concepts in web-based groups moderated by a tutor [48-50]. Forum interaction data were largely analyzed via social network analysis [51].

Test scores constitute data from assessments provided on a digital education platform. In most cases, researchers have collected the accuracy of participant performance in web-based clinical cases or e-cases [52,82]. The next largest group consisted of participants’ scores on the MCQs [41,43]. A total of 2% (1/65) of articles did not specify the type of assessment on which they collected data [75], and 2% (1/65) of articles featured not only MCQs but also fill in the blank, jumbled sentences, and matching questions [25]. In addition, 3% (2/65) of studies collected students’ performance on flash cards [35,40].

Textual data, such as written assessments, discussion forums, and email communications [88], can provide additional insights into the learning process, which are not captured by quantitative data. Among the papers reviewed, we identified 17% (11/65) of papers that digitally collected textual data [3,24,25,34,41,60,66,76,79,84,86]. The majority (6/11, 55%) were open question responses from web-based surveys [24,25,60,76,79,86]. Other types of textual data collected included forum comments [3,84], user-submitted questions [66], e-case summary statements [41], and e-case annotations [34]. Textual data were generally analyzed manually, such as in a study by Colthorpe et al [24], where the authors manually categorized open question response data based on an existing classification system. However, 5% (3/65) of articles used machine learning tools to analyze textual data [34,41,66]. For example, Harrak et al [66] used an automatic annotation tool to analyze questions submitted by students to a digital education platform. The tool identified keywords in student questions, weighed them, and divided the questions into different sentences.

We identified 5 analytic approaches used to process the collected data on students using digital education content (Table S5 in Multimedia Appendix 1): (1) descriptive statistics, (2) inferential statistics, (3) data visualization, (4) machine learning, and (5) social network analysis. Descriptive statistics summarize the characteristics of the collected data. Inferential statistics allow researchers to make predictions about the data [89]. Data visualization is used to present values visually [90]. Machine learning supports automated learning and makes predictions about collected data [91]. Social network analysis is the process of investigating social structures using the graph theory [76].

Descriptive statistics was the most commonly used approach to summarize the characteristics of the collected data: in 20% (13/65) of papers as the only approach [31,34,35,46,67,68,72-74,76,80,81,86] and in 89% (58/65) of papers as one of the used approaches [3,24-31,33-43, 45-56,58-63,65-68,70,72-74,76-87]. Descriptive statistics can be further broken down into measures of central tendency (eg, average, mean, and median) and dispersion (eg, range and SD). The average is defined as the sum of all numbers divided by the total number of values. The median is the middle number in a sorted list of numbers. Mean or average was more frequently used in the reviewed papers as a measure of central tendency than the median. The range is calculated as the maximum value minus the minimum value in the data set. SD measures the amount of data dispersion. Range and SD were almost equally used throughout the reviewed studies. Descriptive statistics measures were typically used to compare different student groups; for example, among the active, passive, and selective groups in a study by Ahmad et al [39]; English, Spanish, and French users in a study by Brands et al [81]; or different cohorts in a study by Alexander et al [67].

Inferential statistics used for hypothesis testing can be divided into correlation, regression, and difference analysis. This was the second most popular approach, used in 62% (40/65) of papers [24,25,29,30,33,36-41,43,45,47-56,58,59,62,63,65,66, 70,71,75,77-79,82-85,87]. This correlation indicates whether the 2 data types collected are related. Regression investigates the relationship between an outcome (ie, dependent variables) and independent variables. The purpose of the difference analysis is to test the differences between the means of variables. Inferential statistics can be divided into parametric and nonparametric tests. Parametric tests make assumptions about the parameters of the population distribution from which the sample is drawn, whereas nonparametric tests are distribution free.

A correlation coefficient (eg, Pearson, Kendall, and Spearman) is used to measure the strength of the relationship between numeric data types. For the Pearson correlation, both variables should be normally distributed. Kendall rank correlation and Spearman rank correlation do not carry any assumptions about the distribution of the data. Pearson correlation was used more often than Spearman correlation. Kendall rank correlation was only used in a study by Saqr et al [50]. Chi-square tests are used to determine whether nominal data types are associated. Chi-square tests were performed in a total of 15% (10/65) of papers [25,41,49,50,53,54,71,79,82,83]. The correlation was typically used to determine the variation in different data types collected through digital education platforms (eg, number of log-ins, total time, or time per question) and examination performance (eg, final grade) [29,55] or course completion [83].

Regression analysis can be divided into linear and logistic regression, depending on whether the outcome is continuous or dichotomous, or multivariable and multivariate, depending on whether there is 1 outcome or ≥1 outcome. Linear regression was used slightly more often than logistic regression. In addition to multivariate and multivariable regressions, generalized linear model was used in studies by Cirigliano et al [65] and Mu et al [53], automatic linear model was used in studies by Perumal et al [75] and Saqr et al [50], whereas the quadratic assignment procedure logistic regression was used in a study by Saqr and Montero [38]. Throughout the reviewed papers, the authors used collected data, such as age and attendance [25] and videos and quizzes accessed [56], as independent variables to predict dependent variables, such as student accuracy on the MCQ as a general indicator of successful engagement [65] or for the prediction of at-risk students [75].

Difference analysis or mean differences can be parametric (eg, t test or ANOVA) or nonparametric (eg, Mann-Whitney U test or Wilcoxon signed-rank test). In the papers, parametric tests were used in 22% (14/65) of instances [24,30,43,47,53-55,58,71,77,78,84,85,87], whereas nonparametric tests were used 14% (9/65) of the times [24,39,45,52,55,66,77,78,83]. Among parametric tests, ANOVA and t tests were used almost equally frequently. Mann-Whitney U test was more frequently used as a nonparametric test than others. For example, difference analysis was used to show substantial differences between an experimental group using a Smart Tutoring System in Moodle and a control group that did not use it [77] or showed that the students’ use of digital education was associated with their subjects’ final status (ie, success or failure) [78].

Data visualization techniques used in the analyzed papers can be divided into heat maps, learning path maps, and sociograms. Heat maps, used in 11% (7/65) of different studies, are visual representations of data that use color depth to make it more intuitive to interpret and evaluate the data [24,33,52,53,57,60,79]. Learning path maps, used to present the collected data in 11% (7/65) of papers, helped to visualize different course units that students master during a specific subject or program [28,29,32,33,37,42,69]. A sociogram is a visual representation of a person’s social connections. It was used in addition to other social network analysis techniques in 11% (7/65) of studies [38,48-51,54,59].

Machine learning approaches consist of 2 types: supervised and unsupervised. Supervised learning makes use of labeled data sets to train or supervise algorithms so that they can accurately identify data or forecast outcomes. In the reviewed papers, supervised machine learning was mostly used for classification tasks; for example, decision tree analysis was used to understand the relationship between the initially selected diagnostic hypotheses while examining web-based patient’s cases and the final submitted hypothesis [27], support vector machines was used to predict students’ final results in blended learning courses using student access time series generated from Moodle log [44], and naive Bayes network was used to provide students with feedback on the quality of their asked questions [66]. Unsupervised learning analyzes and clusters unlabeled data sets that can be used to identify hidden patterns in the data. k-means was the most popular unsupervised algorithm used in 9% (6/65) of papers, mostly as a mechanism for the early detection of at-risk students [24,26,58,66,77,79].

Social network analysis can be divided into individual-level and group/network-level measures and can be either static or dynamic. Individual-level measures are calculated on the level of an individual (ie, a student). Group or network-level data represent a group of students or the whole class (ie, the network). Individual-level measures can be further divided into a quantity of interaction, position in information exchange, and connectedness. Group or network-level measures included centrality, structure, embeddedness, and cohesion.

The quantity of interaction denotes how many interactions a student had in total (ie, degree centrality). One can also separately examine a measure of popularity (ie, in-degree centrality) or a measure of outgoing interaction diversity (ie, out-degree centrality). Position in information exchange (eg, betweenness centrality, information centrality, and closeness centrality) defines the role of students in information exchange in comparison with other students. Connectedness (eg, eigenvector centrality and clustering coefficient) denotes the proportion of the theoretical number of connections that have been achieved. Individual-level measures were calculated in almost all papers, except in a study by Jan and Vlachopoulos [3], where the authors focused only on calculating group-level measures, which were used for community detection.

Centrality measures denote the distribution of centrality measures within the group or network. The structure of the graph includes node count (ie, the number of students in each network), edge count (ie, the number of interactions), the average distance between all pairs of nodes, and average degree (ie, the average number of edges per node). Embeddedness includes network density and reciprocity. Network density is the proportion of actual interactions to the greatest feasible ratio among all members. Reciprocity is the ratio of reciprocated edges when 2 individuals exchange their responses. Cohesion includes efficiency, vulnerability, and transitivity. Efficiency is a valuable indicator of a network’s robustness and tolerance to limited failures or the removal of a small number of members. Vulnerability is a measure of graph sensitivity to information flow disturbance. Transitivity is the tendency of 2 individuals who have a common connection and a structural network characteristic that appears as triangles of nodes. Group-level measures were calculated in all 14% (9/65) of papers that used social network analysis [3,38,48-51,54,59,62].

In the reviewed papers, forum interactions were used as a type of data for building social networks to examine the properties of community-based [3] and problem-based learning [49,51]. More specifically, students’ positions, interactions, and relationships in a network were used to predict their final performance. The most important predictors were information centrality and eigenvector centrality [50]. It was also shown that larger groups are associated with the decreased performance of individual students, as a high group size led to a less cohesive group, with less information exchange among students [48]. On the other hand, the well-performing groups were characterized by active and reciprocal interactions among students and group cohesion measures (transitivity and reciprocity) [59].

The purposes for which LA data were used in the literature were (1) understanding and (2) optimizing learning and the contexts in which it occurs (Table S6 in Multimedia Appendix 1). Under the category of understanding, the purpose of LA can be further divided into the subcategories of understanding user interactions with the digital education platform and understanding the relationship between those interactions and user performance. The category of optimizing can also be subdivided into the subcategories of providing feedback, at-risk intervention, and adaptive learning.

Understanding interactions involves conducting LA to understand how students use the digital education platform. This could be as simple as examining the mean number of connections to a given material or as complicated as modeling how students make decisions in an e-case task. The interactions subcategory comprised the largest group in the papers we reviewed, with 91% (59/65) of papers examining patterns in student use of the platform [3,24-47,49,50, 52,53,55-58,60-62,64-74,76-87]. Although more than a half of the papers (36/59, 61%) had at least one other purpose of understanding aside from understanding the interactions [24,25,29,30,33,34,36-41,43,44,47,49,50,52,53,55,58,62,64-68,71,77-79,82-86], 39% (23/59) of the papers focused only on understanding the interactions [3,26-28,31,32,35,42,45,46,56,57,60,61,69, 70,72-74,76,80,81,87]. For instance, Brands et al [81] used a combination of user statistics from the course digital education platform and student course evaluations to gauge student use of and satisfaction with a web-based course. On a larger scale, Kim and Kim [80] aggregated LA data from 36 medical schools in Korea to examine trends in student use of digital education content.

Understanding performance involves the investigation of the relationship between learners’ interactions with the digital education platform and their performance. Performance can be evaluated in terms of student knowledge, skills, and attitudes. By examining the relationship between LA data and performance variables, authors can make conclusions about whether the use of digital education content leads to better outcomes and, if so, which type of content is more beneficial to students than others. As the second-largest category, a total of 65% (42/65) of papers fell under this group [24,25,29,30,33,34,36-41,43,44,47-55,58,59,62-68,71,75,77-79,82-86]. For example, Ahmad et al [39] used data on students’ patterns of digital education content use to group students according to their time management strategies. They then examined the relationship between these time management strategies and students’ academic performance.

Feedback, under the category of optimizing learning, involves the use of LA data to directly provide information to students about their learning. All articles (6/65, 9%) identified in this category provided feedback based on student performance on e-tests [33,34,53,55,58,77]. The feedback itself consisted simply of whether the students’ responses were correct, often accompanied by a further explanation of the correct answer. For example, Sáiz-Manzanares et al [58] provided learners with feedback on web-based patient cases with MCQs about theoretical knowledge as well as actions that should be taken to treat the patient. Once the learner selected an answer, they received feedback indicating whether it was correct as well as the appropriate actions that needed to be taken for the patient (eg, “You should call a cardiology consultant immediately”) and an explanation of the correct answer. In addition, hints were provided to guide students in performing the correct action.

At-risk intervention aims to provide additional support to students determined to be at risk of, for example, failing a course. To determine a student’s risk, educators must first construct a predictive model that describes the relationship between predictors (eg, scores on formative assessments) and course failure. We identified 20% (13/65) of papers where the authors stopped short of presenting a model that could be used to predict student performance in the future [34,37,38,44,50,54,55,58,59,66,72,75,79]. However, only 1 study has put this predictive model into practice by providing interventions, namely, in a study by Sáiz-Manzanares et al [79], the authors constructed a model of students’ risk of dropping out of the course based on which course educators provided personalized tutoring to at-risk students.

Adaptive learning in the educational context involves a system in which learners’ interactions with digital content determine, at least partly, the nature of future content delivered to them [92]. In this review, we found only 6% (4/65) of instances of adaptive learning [29,30,40,57]. As with papers in the feedback subcategory, most of these studies used test scores as the basis for determining subsequent digital content. In the study by Linden et al [30], when students answered questions incorrectly, they were provided with a set of explanatory content, after which they had the opportunity to answer the same question again before being shown the next topic. In a study by Liu et al [29], the authors implemented a more involved form of adaptive learning: learners took a diagnostic test at the start of the module based on which the digital education platform created a personalized learning path and study plan for the student. Moreover, students could use the Test Me function to test themselves again, which would cause corresponding changes in their study plan. Finally, the platform mentioned in a study by Menon et al [40] used a combination of learner accuracy and confidence on test questions to space the repetition of test items. An exception to this trend could be seen in a study by Gilliland [57], where the authors used the frequency of student engagement with particular topics on the learning platform as a proxy for the perceived difficulty of said content. They then communicated these findings to educators so that more teaching time could be allocated to challenging topics.

Although this scoping review was conducted according to the scoping review methodology, some limitations are worth noting. This review was guided by a formal protocol. To ensure a broad search of the literature, the search strategy included 10 databases; however, our inclusion criteria limited our review results to only English-language articles and published peer-reviewed literature from January 2010 to October 2021. Furthermore, as the data were extracted by 6 reviewers, we used the standardized extraction form to ensure consistency among reviewers. Nevertheless, the extraction process might be slightly affected by the presence of multiple reviewers. A final limitation is the rapid growth of the field; therefore, it is important to acknowledge that this scoping review is a snapshot at a particular point in time. Unlike traditional systematic reviews guided by well-defined constructs, in scooping reviews, it might be unfeasible to screen and synthesize all relevant literature on an emergent topic [133]. As our purpose was to primarily understand what LA techniques have been used in the education of health care professionals, our efforts to identify all eligible studies were limited in some respects.

Our findings highlighted the need to develop an LA-specific implementation framework, drawing on empirical research related to LA efforts and drawing on existing knowledge and experience within the implementation science community. LA should be at the center of designing and redesigning courses for health care professionals. Namely, planning how LA should support the evolution of a course should come before the course starts rather than at its end. Finally, there is no need to repeat the mistakes that have already been made, and there is an opportunity to use the practical insights from existing research to provide an evidence-based foundation that can accelerate the implementation of LA for the development of professional health courses.

In this paper, we reviewed 65 papers in which the authors used LA to collect data on health care professions in their classes. From these papers, we extracted some general characteristics of the whole LA process and proposed a framework for the whole LA life cycle that is field independent, meaning it can be used beyond health care professions education. We then used the proposed framework to review the 65 papers.

Our study is student-centric, although we acknowledge that, in addition to students, there are other stakeholders such as educators and institutions involved in the entire LA process. We focused on students because most of the reviewed papers focused on students. This is consistent with the findings of Lee and Recker [133], where out of 47 reviewed papers, only 3 studies did not focus, at least partly, on students.

Finally, we identified the gaps in the current literature and proposed how they could be closed. The main limitation of almost all the papers we reviewed is that they did not use LA to iteratively inform course design and redesign. The purpose of collecting and analyzing LA data was mostly for an exploratory analysis or predictive analysis conducted within the borders of the same year or cohort. This means that the results of data analytics were not used to improve subsequent classes but rather to make some predictions about students who had already finished that class. In this sense, the potential of LA in health care professions education is not fully used.