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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JMIR</journal-id>
      <journal-id journal-id-type="nlm-ta">J Med Internet Res</journal-id>
      <journal-title>Journal of Medical Internet Research</journal-title>
      <issn pub-type="epub">1438-8871</issn>
      <publisher>
        <publisher-name>JMIR Publications</publisher-name>
        <publisher-loc>Toronto, Canada</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">v24i6e34479</article-id>
      <article-id pub-id-type="pmid">35648457</article-id>
      <article-id pub-id-type="doi">10.2196/34479</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Review</subject>
        </subj-group>
        <subj-group subj-group-type="article-type">
          <subject>Review</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Strategies for Implementing Occupational eMental Health Interventions: Scoping Review</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="editor">
          <name>
            <surname>Kukafka</surname>
            <given-names>Rita</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Deady</surname>
            <given-names>Mark</given-names>
          </name>
        </contrib>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Wall</surname>
            <given-names>Karen</given-names>
          </name>
        </contrib>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Guinemer</surname>
            <given-names>Camille</given-names>
          </name>
        </contrib>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Mircheva</surname>
            <given-names>Iskra</given-names>
          </name>
        </contrib>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Tickner</surname>
            <given-names>Campbell</given-names>
          </name>
        </contrib>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Sinha</surname>
            <given-names>Chaitali</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib id="contrib1" contrib-type="author" corresp="yes">
          <name name-style="western">
            <surname>Bernard</surname>
            <given-names>Renaldo M</given-names>
          </name>
          <degrees>PhD</degrees>
          <xref rid="aff01" ref-type="aff">1</xref>
          <address>
            <institution>Swiss Paraplegic Research</institution>
            <addr-line>Guido A. Zäch-Strasse 4</addr-line>
            <addr-line>Nottwil, 6207</addr-line>
            <country>Switzerland</country>
            <phone>41 419396654</phone>
            <email>renaldo.bernard@paraplegie.ch</email>
          </address>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-6958-3369</ext-link>
        </contrib>
        <contrib id="contrib2" contrib-type="author">
          <name name-style="western">
            <surname>Toppo</surname>
            <given-names>Claudia</given-names>
          </name>
          <degrees>MSc</degrees>
          <xref rid="aff02" ref-type="aff">2</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-1312-6679</ext-link>
        </contrib>
        <contrib id="contrib3" contrib-type="author">
          <name name-style="western">
            <surname>Raggi</surname>
            <given-names>Alberto</given-names>
          </name>
          <degrees>PhD</degrees>
          <xref rid="aff02" ref-type="aff">2</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-7433-7779</ext-link>
        </contrib>
        <contrib id="contrib4" contrib-type="author">
          <name name-style="western">
            <surname>de Mul</surname>
            <given-names>Marleen</given-names>
          </name>
          <degrees>PhD</degrees>
          <xref rid="aff03" ref-type="aff">3</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0003-3447-5920</ext-link>
        </contrib>
        <contrib id="contrib5" contrib-type="author">
          <name name-style="western">
            <surname>de Miquel</surname>
            <given-names>Carlota</given-names>
          </name>
          <degrees>MSc</degrees>
          <xref rid="aff04" ref-type="aff">4</xref>
          <xref rid="aff05" ref-type="aff">5</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0003-3602-4146</ext-link>
        </contrib>
        <contrib id="contrib6" contrib-type="author">
          <name name-style="western">
            <surname>Pugliese</surname>
            <given-names>Maria Teresa</given-names>
          </name>
          <degrees>MSc</degrees>
          <xref rid="aff02" ref-type="aff">2</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0003-4453-9908</ext-link>
        </contrib>
        <contrib id="contrib7" contrib-type="author">
          <name name-style="western">
            <surname>van der Feltz-Cornelis</surname>
            <given-names>Christina M</given-names>
          </name>
          <degrees>MD, PhD</degrees>
          <xref rid="aff06" ref-type="aff">6</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0001-6925-8956</ext-link>
        </contrib>
        <contrib id="contrib8" contrib-type="author">
          <name name-style="western">
            <surname>Ortiz-Tallo</surname>
            <given-names>Ana</given-names>
          </name>
          <degrees>MSc</degrees>
          <xref rid="aff05" ref-type="aff">5</xref>
          <xref rid="aff07" ref-type="aff">7</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-1176-3930</ext-link>
        </contrib>
        <contrib id="contrib9" contrib-type="author">
          <name name-style="western">
            <surname>Salvador-Carulla</surname>
            <given-names>Luis</given-names>
          </name>
          <degrees>PhD</degrees>
          <xref rid="aff08" ref-type="aff">8</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-5742-9866</ext-link>
        </contrib>
        <contrib id="contrib10" contrib-type="author">
          <name name-style="western">
            <surname>Lukersmith</surname>
            <given-names>Sue</given-names>
          </name>
          <degrees>PhD</degrees>
          <xref rid="aff08" ref-type="aff">8</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0001-8202-3828</ext-link>
        </contrib>
        <contrib id="contrib11" contrib-type="author">
          <name name-style="western">
            <surname>Hakkaart-van Roijen</surname>
            <given-names>Leona</given-names>
          </name>
          <degrees>PhD</degrees>
          <xref rid="aff03" ref-type="aff">3</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0003-0635-7388</ext-link>
        </contrib>
        <contrib id="contrib12" contrib-type="author">
          <name name-style="western">
            <surname>Merecz-Kot</surname>
            <given-names>Dorota</given-names>
          </name>
          <degrees>PhD</degrees>
          <xref rid="aff09" ref-type="aff">9</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-8294-4309</ext-link>
        </contrib>
        <contrib id="contrib13" contrib-type="author">
          <name name-style="western">
            <surname>Staszewska</surname>
            <given-names>Kaja</given-names>
          </name>
          <degrees>MA</degrees>
          <xref rid="aff10" ref-type="aff">10</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-1278-3482</ext-link>
        </contrib>
        <contrib id="contrib14" contrib-type="author">
          <name name-style="western">
            <surname>Sabariego</surname>
            <given-names>Carla</given-names>
          </name>
          <degrees>PhD</degrees>
          <xref rid="aff01" ref-type="aff">1</xref>
          <xref rid="aff11" ref-type="aff">11</xref>
          <xref rid="aff12" ref-type="aff">12</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0001-6946-0177</ext-link>
        </contrib>
      </contrib-group>
      <aff id="aff01">
        <label>1</label>
        <institution>Swiss Paraplegic Research</institution>
        <addr-line>Nottwil</addr-line>
        <country>Switzerland</country>
      </aff>
      <aff id="aff02">
        <label>2</label>
        <institution>Neurology, Public Health and Disability Unit</institution>
        <institution>Fondazione IRCCS Istituto Neurologico Carlo Besta</institution>
        <addr-line>Milano</addr-line>
        <country>Italy</country>
      </aff>
      <aff id="aff03">
        <label>3</label>
        <institution>Erasmus School of Health Policy &#38; Management</institution>
        <institution>Erasmus University</institution>
        <addr-line>Rotterdam</addr-line>
        <country>Netherlands</country>
      </aff>
      <aff id="aff04">
        <label>4</label>
        <institution>Research, Innovation and Teaching Unit</institution>
        <institution>Parc Sanitari Sant Joan de Déu</institution>
        <institution>Universitat de Barcelona</institution>
        <addr-line>Sant Boi de Llobregat</addr-line>
        <country>Spain</country>
      </aff>
      <aff id="aff05">
        <label>5</label>
        <institution>Instituto de Salud Carlos III</institution>
        <institution>Centro de Investigación Biomédica en Red de Salud Mental</institution>
        <addr-line>Madrid</addr-line>
        <country>Spain</country>
      </aff>
      <aff id="aff06">
        <label>6</label>
        <institution>Department of Health Sciences</institution>
        <institution>Hull York Medical School</institution>
        <institution>University of York</institution>
        <addr-line>York</addr-line>
        <country>United Kingdom</country>
      </aff>
      <aff id="aff07">
        <label>7</label>
        <institution>Department of Psychiatry</institution>
        <institution>School of Medicine</institution>
        <institution>Universidad Autónoma de Madrid</institution>
        <addr-line>Madrid</addr-line>
        <country>Spain</country>
      </aff>
      <aff id="aff08">
        <label>8</label>
        <institution>Health Research Institute</institution>
        <institution>Faculty of Health</institution>
        <institution>University of Canberra</institution>
        <addr-line>Canberra</addr-line>
        <country>Australia</country>
      </aff>
      <aff id="aff09">
        <label>9</label>
        <institution>Institute of Psychology</institution>
        <institution>University of Lodz</institution>
        <addr-line>Lodz</addr-line>
        <country>Poland</country>
      </aff>
      <aff id="aff10">
        <label>10</label>
        <institution>Department of Health and Work Psychology</institution>
        <institution>Nofer Institute of Occupational Medicine</institution>
        <addr-line>Lodz</addr-line>
        <country>Poland</country>
      </aff>
      <aff id="aff11">
        <label>11</label>
        <institution>Department of Health Sciences and Medicine</institution>
        <institution>University of Lucerne</institution>
        <addr-line>Lucerne</addr-line>
        <country>Switzerland</country>
      </aff>
      <aff id="aff12">
        <label>12</label>
        <institution>Center for Rehabilitation in Global Health Systems</institution>
        <institution>World Health Organization Collaborating Center</institution>
        <institution>University of Lucerne</institution>
        <addr-line>Lucerne</addr-line>
        <country>Switzerland</country>
      </aff>
      <author-notes>
        <corresp>Corresponding Author: Renaldo M Bernard <email>renaldo.bernard@paraplegie.ch</email></corresp>
      </author-notes>
      <pub-date pub-type="collection">
        <month>6</month>
        <year>2022</year>
      </pub-date>
      <pub-date pub-type="epub">
        <day>1</day>
        <month>6</month>
        <year>2022</year>
      </pub-date>
      <volume>24</volume>
      <issue>6</issue>
      <elocation-id>e34479</elocation-id>
      <history>
        <date date-type="received">
          <day>28</day>
          <month>10</month>
          <year>2021</year>
        </date>
        <date date-type="rev-request">
          <day>27</day>
          <month>12</month>
          <year>2021</year>
        </date>
        <date date-type="rev-recd">
          <day>2</day>
          <month>3</month>
          <year>2022</year>
        </date>
        <date date-type="accepted">
          <day>30</day>
          <month>3</month>
          <year>2022</year>
        </date>
      </history>
      <copyright-statement>©Renaldo M Bernard, Claudia Toppo, Alberto Raggi, Marleen de Mul, Carlota de Miquel, Maria Teresa Pugliese, Christina M van der Feltz-Cornelis, Ana Ortiz-Tallo, Luis Salvador-Carulla, Sue Lukersmith, Leona Hakkaart-van Roijen, Dorota Merecz-Kot, Kaja Staszewska, Carla Sabariego. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 01.06.2022.</copyright-statement>
      <copyright-year>2022</copyright-year>
      <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
        <p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Journal of Medical Internet Research, is properly cited. The complete bibliographic information, a link to the original publication on https://www.jmir.org/, as well as this copyright and license information must be included.</p>
      </license>
      <self-uri xlink:href="https://www.jmir.org/2022/6/e34479" xlink:type="simple"/>
      <abstract>
        <sec sec-type="background">
          <title>Background</title>
          <p>The implementation of eMental health interventions, especially in the workplace, is a complex process. Therefore, learning from existing implementation strategies is imperative to ensure improvements in the adoption, development, and scalability of occupational eMental health (OeMH) interventions. However, the implementation strategies used for these interventions are often undocumented or inadequately reported and have not been systematically gathered across implementations in a way that can serve as a much-needed guide for researchers.</p>
        </sec>
        <sec sec-type="objective">
          <title>Objective</title>
          <p>The objective of this scoping review was to identify implementation strategies relevant to the uptake of OeMH interventions that target employees and detail the associated barriers and facilitation measures.</p>
        </sec>
        <sec sec-type="methods">
          <title>Methods</title>
          <p>A scoping review was conducted. The descriptive synthesis was guided by the RE-AIM (reach, effectiveness, adoption, implementation, and maintenance) framework and the Consolidated Framework for Implementation Research.</p>
        </sec>
        <sec sec-type="results">
          <title>Results</title>
          <p>A total of 31 of 32,916 (0.09%) publications reporting the use of the web-, smartphone-, telephone-, and email-based OeMH interventions were included. In all, 98 implementation strategies, 114 barriers, and 131 facilitators were identified. The synthesis of barriers and facilitators produced 19 facilitation measures that provide initial recommendations for improving the implementation of OeMH interventions.</p>
        </sec>
        <sec sec-type="conclusions">
          <title>Conclusions</title>
          <p>This scoping review represents one of the first steps in a research agenda aimed at improving the implementation of OeMH interventions by systematically selecting, shaping, evaluating, and reporting implementation strategies. There is a dire need for improved reporting of implementation strategies and combining common implementation frameworks with more technology-centric implementation frameworks to fully capture the complexities of eHealth implementation. Future research should investigate a wider range of common implementation outcomes for OeMH interventions that also focus on a wider set of common mental health problems in the workplace. This scoping review’s findings can be critically leveraged by discerning decision-makers to improve the reach, effectiveness, adoption, implementation, and maintenance of OeMH interventions.</p>
        </sec>
      </abstract>
      <kwd-group>
        <kwd>implementation</kwd>
        <kwd>mobile health</kwd>
        <kwd>mHealth</kwd>
        <kwd>mental health</kwd>
        <kwd>eMental health</kwd>
        <kwd>occupational health</kwd>
        <kwd>barriers</kwd>
        <kwd>facilitators</kwd>
        <kwd>scoping review</kwd>
        <kwd>mobile phone</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec sec-type="introduction">
      <title>Introduction</title>
      <sec>
        <title>Background</title>
        <p>Mental health problems experienced by the working population are a global public health issue. Worldwide, more than 210 million people, representing 70% of those affected by common mental health disorders (eg, anxiety and mood disorders) are employed [<xref ref-type="bibr" rid="ref1">1</xref>]. Several risk factors, including working conditions, workplace culture, and the nature of work, have been linked to occupational mental health [<xref ref-type="bibr" rid="ref2">2</xref>-<xref ref-type="bibr" rid="ref4">4</xref>]. Public health emergencies, such as the COVID-19 pandemic, are linked to specific stressors, including the threat of infection, social distancing measures, stigma, and job insecurity, which considerably increase the prevalence of mental health problems in the working population [<xref ref-type="bibr" rid="ref5">5</xref>].</p>
        <p>Occupational eMental health (OeMH) interventions significantly improve mental health in work settings [<xref ref-type="bibr" rid="ref6">6</xref>]. OeMH interventions use information and communication technology, including internet- and web-based services, mobile apps, and wearable technologies, to deliver knowledge and services such as psychoeducation, workplace health promotion, psychological and medical treatment, and return to work assistance to employees [<xref ref-type="bibr" rid="ref7">7</xref>,<xref ref-type="bibr" rid="ref8">8</xref>]. OeMH interventions have the potential to be more available, accessible, and scalable than traditional interventions [<xref ref-type="bibr" rid="ref9">9</xref>,<xref ref-type="bibr" rid="ref10">10</xref>], especially in public health emergencies, leading to physical-distancing policies to contain the spread of threatening conditions such as COVID-19.</p>
        <p>However, implementing OeMH interventions is a complex process characterized by unique challenges involving adherence to new and crude regulatory frameworks, interoperability and compatibility with existing systems and procedures, threats to employees, organizational privacy and security, and associated costs [<xref ref-type="bibr" rid="ref11">11</xref>]. Newly introduced working arrangements in response to public health emergencies, such as the COVID-19 pandemic, could also compound existing implementation challenges and persist after the pandemic ends. Carefully developing and planning implementation strategies, which can be defined as a method or technique used to enhance the adoption, execution plan, and sustainability of an intervention [<xref ref-type="bibr" rid="ref12">12</xref>], is therefore essential to guarantee the sustainable uptake of OeMH interventions by employers and employees.</p>
        <p>Nonetheless, it is difficult to establish a best practice for the implementation of OeMH interventions. Implementation strategies are often inadequately documented and seldom evaluated and published [<xref ref-type="bibr" rid="ref12">12</xref>,<xref ref-type="bibr" rid="ref13">13</xref>], especially in comparison with studies on the effectiveness of interventions. Even when reported, implementation strategies have been discussed within a general context, and researchers have called for more tailored implementation strategies that focus on specific contexts [<xref ref-type="bibr" rid="ref14">14</xref>], for instance health care [<xref ref-type="bibr" rid="ref15">15</xref>]. Context encompasses the environment, broad setting, and circumstances (eg, systems and structures) in which an intervention is implemented and its associated characteristics [<xref ref-type="bibr" rid="ref16">16</xref>]. It is a key component of several widely adopted implementation frameworks, as evident in the Consolidated Framework for Implementation Research (CFIR) [<xref ref-type="bibr" rid="ref17">17</xref>]. Currently, those implementing new OeMH interventions are likely insufficiently informed about the procedure, strengths, and weaknesses of poorly documented implementation strategies, or uninformed about many potentially useful facilitators in this context. Furthermore, replicating positive results from similar implementations or overcoming barriers encountered in similar contexts would be challenging to achieve [<xref ref-type="bibr" rid="ref18">18</xref>,<xref ref-type="bibr" rid="ref19">19</xref>].</p>
      </sec>
      <sec>
        <title>Objectives</title>
        <p>Therefore, a compilation of possible implementation strategies for OeMH interventions is critical to fostering improvements in their uptake and can serve as a reference for identifying and overcoming likely barriers and informing the future development of best practices. The objective of this scoping review was to identify implementation strategies relevant to the uptake of OeMH interventions that target employees and detail the associated barriers and facilitation measures. This scoping review would achieve these objectives by mapping the existing literature on the implementation of OeMH interventions and identifying gaps for future research. This work was conducted under the EMPOWER (European Platform to Promote Well-being and Health in the Workplace) project, funded by the European Commission, which investigates the impact of an eMental health platform aimed at preventing common mental health problems and reducing psychological distress in the workplace [<xref ref-type="bibr" rid="ref20">20</xref>]. It is also one of the series of review papers on different aspects of the knowledge base related to the development of the EMPOWER platform.</p>
      </sec>
    </sec>
    <sec sec-type="methods">
      <title>Methods</title>
      <sec>
        <title>Overview</title>
        <p>A scoping review was conducted to identify implementation strategies relevant to the implementation of OeMH interventions and to describe related barriers and associated facilitation measures. The scoping review is an established method for assessing and mapping the extent of evidence to address and inform practice in a topic area [<xref ref-type="bibr" rid="ref21">21</xref>-<xref ref-type="bibr" rid="ref24">24</xref>]. The review proceeded through five stages as developed by Arksey and O’Malley [<xref ref-type="bibr" rid="ref23">23</xref>], extended by Levac et al [<xref ref-type="bibr" rid="ref22">22</xref>], and further modified by Westphaln et al [<xref ref-type="bibr" rid="ref25">25</xref>] to accommodate a team-based approach: (1) identifying the research question; (2) identifying relevant studies; (3) selecting studies; (4) charting the data; and (5) collating, summarizing, and reporting the results. Accordingly, this scoping review provides an overview of the existing evidence without a formal assessment of the methodological quality. It is conducted and reported in accordance with the widely adopted PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews) [<xref ref-type="bibr" rid="ref26">26</xref>] to help ensure a high level of methodological rigor and reporting quality.</p>
      </sec>
      <sec>
        <title>Search Strategy</title>
        <p>Electronic bibliographic databases, including MEDLINE, Scopus, CINAHL Complete, PsycINFO, and Web of Science Core Collection, were searched to find eligible peer-reviewed and gray literature. Search terms were based on concepts related to mental health, digital tools, the workplace, and implementation strategies (<xref ref-type="supplementary-material" rid="app1">Multimedia Appendix 1</xref>). The MEDLINE search strategy (<xref ref-type="supplementary-material" rid="app1">Multimedia Appendix 1</xref>) was adapted for other databases using relevant syntax and keywords in consultation with all coauthors who are also experienced researchers in the area. Hand searching of the reference lists of included articles was also completed for further relevant literature not identified during the search of databases. Members of the EMPOWER Consortium (ie, mental health researchers, clinicians, and experts focusing on well-being in the workplace) were also requested to suggest potentially eligible references via email.</p>
      </sec>
      <sec>
        <title>Eligibility Criteria</title>
        <p>Publications were eligible for inclusion if they described implementation strategies (ie, according to Proctor et al [<xref ref-type="bibr" rid="ref12">12</xref>]) or related barriers or facilitation measures relevant to the uptake of OeMH interventions targeting employees. For example, all other eligibility criteria being met, approaches with the following characteristics would be considered: aim to introduce and encourage continued use of an intervention; prescribe actions in support of the intervention (eg, adaptations, fiscal strategies, and testing); and ensure that interventions can deliver intended benefits to the relevant organization over time, for instance, creating routine organizational policies or best practices. OeMH interventions are broadly defined here as mental health information and services delivered by information and communication technologies to employees [<xref ref-type="bibr" rid="ref7">7</xref>,<xref ref-type="bibr" rid="ref8">8</xref>]. This definition is consistent with the definition of eHealth [<xref ref-type="bibr" rid="ref27">27</xref>,<xref ref-type="bibr" rid="ref28">28</xref>], as well as the broader term digital health [<xref ref-type="bibr" rid="ref27">27</xref>]. Studies with employed participants aged ≥18 years, that were written in English. and published between January 2010 and May 2021 were considered. Primary research studies, systematic reviews, books, and gray literature (eg, conference proceedings, theses, government documents, and professional publications) were considered. Gray literature, such as commentaries, letters to editors, and editorials, were excluded.</p>
      </sec>
      <sec>
        <title>Eligibility Assessment</title>
        <p>A total of 10 researchers (AO-T, AR, CdM, CT, CMvdFC, DM-K, KS, MdM, MTP, and RMB), including psychologists, health scientists, and health economists, were involved in screening. To ensure consistency across researchers, they attended a web-based training workshop to practice the skills needed to reliably execute screening using the web and an app-based service Rayyan, Qatar Computing Research Institute [<xref ref-type="bibr" rid="ref29">29</xref>]. A training set of 100 publications was screened by all workshop attendees. Screening decisions (ie, include, maybe, or exclude) were reviewed and discussed to clarify any misunderstandings and identify difficulties using Rayyan QCRI. Instructions not to use the natural language processing–, artificial intelligence (AI)-, and machine learning–based features offered in Rayyan QCRI as well as tips to overcome minor usability shortcomings were given. Screeners were randomly assigned a screening set, and a screener performed a second screening of 20% of titles, abstracts, and full texts, and 100% of the publications that received a <italic>maybe</italic> screening decision. All screenings were conducted independently to reduce the likelihood of reviewer bias [<xref ref-type="bibr" rid="ref30">30</xref>] and inconsistencies in screening decisions were resolved in reconciliation meetings.</p>
      </sec>
      <sec>
        <title>Data Extraction and Synthesis of Results</title>
        <p>In all, 5 researchers (AR, CdM, CT, MdM, and RMB), including psychologists and health scientists, of the 10 (50%) screeners, were involved in data extraction and attended a web-based training workshop focused on developing consistency across researchers by practicing the skills needed to reliably execute data extraction using a web-based data extraction form. The form was reviewed and improved for clarity regarding the questions asked, user friendliness, and efficiency of data entry. For instance, it was clarified that single-component implementation strategies were to be extracted, and any bundling of strategies (ie, multifaceted strategies) in publications to address a goal were to be noted. Each researcher was randomly assigned an equal number of included records, and a researcher reviewed the extracted data for all the included publications.</p>
        <p>A descriptive synthesis was performed, where identified implementation strategies, barriers, and facilitators were collated and later summarized. The synthesis was conducted by 3 (CT, MdM, and RMB, ie, psychologists and health scientists) of the 6 (50%) researchers involved in data extraction and guided by the RE-AIM (reach, effectiveness, adoption, implementation, and maintenance) framework [<xref ref-type="bibr" rid="ref31">31</xref>-<xref ref-type="bibr" rid="ref33">33</xref>] and the CFIR [<xref ref-type="bibr" rid="ref17">17</xref>] and further informed by the Expert Recommendations for Implementing Change [<xref ref-type="bibr" rid="ref34">34</xref>]. RE-AIM and CFIR were chosen as they are widely used frameworks in implementation research (IR) [<xref ref-type="bibr" rid="ref35">35</xref>] and were deemed by the authors to be the most comprehensive of the recently reviewed implementation frameworks [<xref ref-type="bibr" rid="ref35">35</xref>] and most applicable to our objectives. The RE-AIM was originally developed as a framework for reporting findings regarding health promotion and disease management interventions in various settings. RE-AIM is used here to highlight essential strategy components with respect to its five steps: reach—the number of people who are willing to participate in a given initiative; effectiveness—the impact of an intervention on important outcomes (eg, individualistic and economic); adoption—the number of people or organizations who are willing to initiate and deliver an intervention; implementation—fidelity of delivery for the intervention including adaptations, costs, and consistency of delivery; and maintenance—sustained delivery and effects of an intervention after the associated initiative has ended. The CFIR unifies implementation theories to help build a robust implementation knowledge base across a wide range of studies, settings, contexts, and processes. The CFIR was used to provide a comprehensive view of multiple implementation contexts in which factors that might influence intervention implementation and effectiveness could be well detailed. Both frameworks determined the data for extraction: key publication characteristics, strategy definitions, key strategy implementation tasks, implementation processes, barriers and facilitators to strategy implementation, and any other data that holistically captured the complex and multilevel nature of strategy implementation were considered for data collection. Further synthesis of the identified barriers and facilitators produced recommendations for each relevant CFIR construct to improve the implementation of OeMH interventions.</p>
      </sec>
    </sec>
    <sec sec-type="results">
      <title>Results</title>
      <p>A total of 31 publications were included in this scoping review (<xref ref-type="table" rid="table1">Table 1</xref>). <xref rid="figure1" ref-type="fig">Figure 1</xref> details the methodological process followed, and a detailed itemization of the presented findings is provided in <xref ref-type="supplementary-material" rid="app2">Multimedia Appendices 2</xref> and <xref ref-type="supplementary-material" rid="app3">3</xref>.</p>
      <table-wrap position="float" id="table1">
        <label>Table 1</label>
        <caption>
          <p>Characteristics of included publications and interventions.</p>
        </caption>
        <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
          <col width="130"/>
          <col width="230"/>
          <col width="260"/>
          <col width="230"/>
          <col width="150"/>
          <thead>
            <tr valign="top">
              <td>Citation and year of publication</td>
              <td>Study aim and methods (n)</td>
              <td>Country of implementation, industry, and participating organizations (n)</td>
              <td>Intervention name, aim, and target conditions</td>
              <td>Digital technologies used</td>
            </tr>
          </thead>
          <tbody>
            <tr valign="top">
              <td>[<xref ref-type="bibr" rid="ref36">36</xref>], 2020</td>
              <td>To develop, implement, and evaluate the intervention; survey (503), interviews (19), and focus groups (32)</td>
              <td>United Kingdom; human health and social work activities; 7</td>
              <td>Healthier Outcomes at Work Social Work Project; improve and manage; workplace stress and mental well-being</td>
              <td>Smartphone app</td>
            </tr>
            <tr valign="top">
              <td>[<xref ref-type="bibr" rid="ref37">37</xref>],<sup>a</sup> 2020</td>
              <td>To describe the intervention’s implementation; protocol—pilot randomized controlled trial (106)</td>
              <td>China; human health and social work activities; 1</td>
              <td>Step-by-Step F; improve; depressive symptoms and anxiety symptoms</td>
              <td>Web-based and smartphone app</td>
            </tr>
            <tr valign="top">
              <td>[<xref ref-type="bibr" rid="ref38">38</xref>],<sup>a</sup> 2020</td>
              <td>To describe the evaluation of the intervention’s implementation; protocol—focus groups (N/R<sup>b</sup>)</td>
              <td>Germany; agriculture, forestry, and fishing; N/A<sup>c</sup></td>
              <td>With us in balance; prevent; stress-related disorders, anxiety disorders, mood disorders, substance-related and addictive disorders, insomnia, and chronic pain</td>
              <td>Web-based and telephone</td>
            </tr>
            <tr valign="top">
              <td>[<xref ref-type="bibr" rid="ref39">39</xref>], 2020</td>
              <td>To examine perspectives on the role and legitimacy of the intervention; interviews (32) and focus group (14)</td>
              <td>Sweden; N/R; N/A</td>
              <td>mWorks; support; common mental disorders</td>
              <td>Smartphone app</td>
            </tr>
            <tr valign="top">
              <td>[<xref ref-type="bibr" rid="ref40">40</xref>],<sup>a</sup> 2020</td>
              <td>To conduct preliminary evaluation of the intervention; pilot—usability study (81)</td>
              <td>Australia; N/S<sup>d</sup>; N/R</td>
              <td>Anchored app; assess, improve, and monitor; depression, workplace stress, and mental well-being</td>
              <td>Smartphone app</td>
            </tr>
            <tr valign="top">
              <td>[<xref ref-type="bibr" rid="ref41">41</xref>],<sup>a</sup> 2020</td>
              <td>To rapidly develop and evaluate the intervention; stakeholder consultation groups (97), peer review panel (10), and intervention fidelity and implementation testing (55)</td>
              <td>United Kingdom; human health and social work activities; N/R</td>
              <td>Psychological Well-being in Healthcare Workers: Mitigating the Impacts of COVID-19; support and manage; workplace stress and mental well-being</td>
              <td>Web-based</td>
            </tr>
            <tr valign="top">
              <td>[<xref ref-type="bibr" rid="ref42">42</xref>], 2019</td>
              <td>To evaluate the feasibility, outcome, and acceptability of the intervention; proof-of-concept—survey (33)</td>
              <td>United Kingdom; public administration and defense and compulsory social security; 2</td>
              <td>Self-confidence webinar program; improve; mood disorders and depression</td>
              <td>Web-based</td>
            </tr>
            <tr valign="top">
              <td>[<xref ref-type="bibr" rid="ref43">43</xref>], 2019</td>
              <td>To evaluate engagement with the intervention; survey (149)</td>
              <td>United States; public administration and defense and compulsory social security; 20</td>
              <td>Stress Reduction Training for 9-1-1 Telecommunicators; improve and promote; workplace stress</td>
              <td>Web-based</td>
            </tr>
            <tr valign="top">
              <td>[<xref ref-type="bibr" rid="ref44">44</xref>], 2019</td>
              <td>To conduct formative evaluation of the intervention; interviews (24)</td>
              <td>New Zealand; public administration and defense and compulsory social security; N/R</td>
              <td>N/R; improve; stigma and discrimination</td>
              <td>Web-based</td>
            </tr>
            <tr valign="top">
              <td>[<xref ref-type="bibr" rid="ref45">45</xref>], 2018</td>
              <td>To evaluate adherence to the intervention; randomized controlled study (563)</td>
              <td>Sweden; education; 21</td>
              <td>N/R; improve and promote; workplace stress, occupational health, and sleep quality</td>
              <td>Web-based</td>
            </tr>
            <tr valign="top">
              <td>[<xref ref-type="bibr" rid="ref46">46</xref>], 2018</td>
              <td>To evaluate the helpfulness of the intervention; web-based survey (22) and focus groups (2)</td>
              <td>United States; human health and social work activities; 1</td>
              <td>Paving the Path to Mindfulness Website; improve; burnout and workplace stress</td>
              <td>Web-based</td>
            </tr>
            <tr valign="top">
              <td>[<xref ref-type="bibr" rid="ref47">47</xref>], 2018</td>
              <td>To evaluate acceptance and barriers to the uptake of OeMH<sup>e</sup> interventions; survey (3294)</td>
              <td>N/A; N/A; N/A</td>
              <td>N/A; manage; work-related distress</td>
              <td>N/S</td>
            </tr>
            <tr valign="top">
              <td>[<xref ref-type="bibr" rid="ref48">48</xref>],<sup>a</sup> 2018</td>
              <td>To evaluate the implementation strategy used; controlled trial (221)</td>
              <td>The Netherlands; human health and social work activities; 1</td>
              <td>Stress Prevention@Work; improve and prevent; workplace stress</td>
              <td>Web-based</td>
            </tr>
            <tr valign="top">
              <td>[<xref ref-type="bibr" rid="ref49">49</xref>],<sup>a</sup> 2018</td>
              <td>To evaluate the effectiveness of the implementation strategy used; follow-up controlled trial (252)</td>
              <td>The Netherlands; human health and social work activities; 1</td>
              <td>Stress Prevention@Work (SP@W); assess, improve, and prevent; workplace stress</td>
              <td>Web-based</td>
            </tr>
            <tr valign="top">
              <td>[<xref ref-type="bibr" rid="ref50">50</xref>],<sup>a</sup> 2018</td>
              <td>To identify key correlates of intention to use OeMH interventions; survey (1364)</td>
              <td>China; human health and social work activities; N/A</td>
              <td>N/A; N/A; mental health conditions</td>
              <td>Web-based and smartphone app</td>
            </tr>
            <tr valign="top">
              <td>[<xref ref-type="bibr" rid="ref51">51</xref>],<sup>a</sup> 2018</td>
              <td>To evaluate use of OeMH; log data and survey (1284)</td>
              <td>Sweden; N/R; 6</td>
              <td>N/R; improve, monitor, promote, and support; workplace stress and mental well-being</td>
              <td>Web-based</td>
            </tr>
            <tr valign="top">
              <td>[<xref ref-type="bibr" rid="ref52">52</xref>], 2018</td>
              <td>To develop and pilot-test the usability, acceptability, feasibility, and preliminary effectiveness of the intervention; prototype testing (21) and effectiveness and feasibility pilot study (84)</td>
              <td>Australia; agriculture, forestry and fishing, manufacturing, and logistics; 3</td>
              <td>HeadGear; improve; depressive symptoms</td>
              <td>Smartphone app</td>
            </tr>
            <tr valign="top">
              <td>[<xref ref-type="bibr" rid="ref53">53</xref>],<sup>a</sup> 2018</td>
              <td>To identify facilitators and barriers to engagement with OeMH interventions; interviews (18)</td>
              <td>United Kingdom; information and communication, public administration and defense, education, and other service activities; 6</td>
              <td>WorkGuru; improve; workplace stress</td>
              <td>Web-based</td>
            </tr>
            <tr valign="top">
              <td>[<xref ref-type="bibr" rid="ref54">54</xref>],<sup>a</sup> 2017</td>
              <td>To conduct process evaluation of the intervention; survey, log data, interviews, and observations (132)</td>
              <td>The Netherlands; N/R; 2</td>
              <td>eHealth module embedded in collaborative occupational health care; improve and monitor; mental well-being and return to work</td>
              <td>Web-based</td>
            </tr>
            <tr valign="top">
              <td>[<xref ref-type="bibr" rid="ref55">55</xref>], 2017</td>
              <td>To compare engagement with(out) a discussion group; pilot—3-arm randomized controlled trial (84)</td>
              <td>United Kingdom; information and communication, public administration and defense, compulsory social security, education, and third sector organization; 6</td>
              <td>WorkGuru; educate, improve, and monitor; workplace stress and nonworkplace stress</td>
              <td>Web-based</td>
            </tr>
            <tr valign="top">
              <td>[<xref ref-type="bibr" rid="ref56">56</xref>], 2016</td>
              <td>To investigate the influence of guidance formats on adherence of the intervention; pooled data from randomized  <break/>  
            controlled trials (395)</td>
              <td>Germany; N/R; N/R</td>
              <td>GET.ON Stress; improve and manage; workplace stress</td>
              <td>Smartphone app</td>
            </tr>
            <tr valign="top">
              <td>[<xref ref-type="bibr" rid="ref57">57</xref>], 2016</td>
              <td>To investigate men’s preferences for OeMH interventions’ design features; cross-sectional survey (841)</td>
              <td>Canada; N/A; N/A</td>
              <td>N/A; N/A; workplace stress and major depression</td>
              <td>N/A</td>
            </tr>
            <tr valign="top">
              <td>[<xref ref-type="bibr" rid="ref58">58</xref>], 2016</td>
              <td>To describe the development, implementation, and outcomes of; survey (1333)</td>
              <td>United States; human health and social work activities; 1</td>
              <td>Sleep Smart; improve and promote; poor sleep health</td>
              <td>Email</td>
            </tr>
            <tr valign="top">
              <td>[<xref ref-type="bibr" rid="ref8">8</xref>],<sup>a</sup> 2016</td>
              <td>To describe approaches to and perspectives on OeMH interventions; N/A (N/A)</td>
              <td>N/A; N/S; N/A</td>
              <td>N/A; N/A; N/A</td>
              <td>N/S</td>
            </tr>
            <tr valign="top">
              <td>[<xref ref-type="bibr" rid="ref59">59</xref>], 2016</td>
              <td>To evaluate the potential effectiveness of the intervention and the effect of an online facilitated discussion group on engagement; protocol—3-arm randomized controlled trial (90)</td>
              <td>United Kingdom; N/R; N/A</td>
              <td>WorkGuru; educate, improve, and monitor; Workplace stress and nonworkplace stress</td>
              <td>Web-based</td>
            </tr>
            <tr valign="top">
              <td>[<xref ref-type="bibr" rid="ref60">60</xref>], 2015</td>
              <td>To describe the development the intervention; individual (34) and focus group (18) feedback sessions</td>
              <td>United States; public administration and defense, compulsory social security, and human health and social work activities; N/R</td>
              <td>Coming Home and Moving Forward; improve; stress-related disorders and substance-related and addictive disorders</td>
              <td>Web-based</td>
            </tr>
            <tr valign="top">
              <td>[<xref ref-type="bibr" rid="ref61">61</xref>], 2014</td>
              <td>To investigate users’ views on two different technologies for an OeMH intervention; survey within randomized controlled trial (637)</td>
              <td>United Kingdom; transportation and storage, information and communication, and human health and social work activities; 3</td>
              <td>Mood GYM; improve; mood disorders</td>
              <td>Web-based</td>
            </tr>
            <tr valign="top">
              <td>[<xref ref-type="bibr" rid="ref62">62</xref>],<sup>a</sup> 2014</td>
              <td>To contrast the role of differing managerial levels during the implementation of an OeMH; interviews (29)</td>
              <td>Sweden; information and communication; public administration and defense; compulsory social security; education; and arts, entertainment, and recreation; 9</td>
              <td>N/R; assess, improve, monitor, and promote; mental well-being</td>
              <td>Web-based</td>
            </tr>
            <tr valign="top">
              <td>[<xref ref-type="bibr" rid="ref63">63</xref>],<sup>a</sup> 2014</td>
              <td>To assess the feasibility of the intervention and explore barriers and /facilitators for the implementation of the intervention; process evaluation alongside a randomized controlled trial (116)</td>
              <td>The Netherlands; financial and insurance activities; professional, scientific, and technical activities; public administration and defense; compulsory social security; and education; 6</td>
              <td>Happy Work; improve and prevent; depressive symptoms</td>
              <td>Web-based</td>
            </tr>
            <tr valign="top">
              <td>[<xref ref-type="bibr" rid="ref64">64</xref>],<sup>a</sup> 2013</td>
              <td>To describe the development and implementation of the intervention; N/A (N/A)</td>
              <td>International; N/R; N/R</td>
              <td>HealthWatch; manage, prevent, and promote; mental well-being</td>
              <td>Web-based</td>
            </tr>
            <tr valign="top">
              <td>[<xref ref-type="bibr" rid="ref65">65</xref>], 2010</td>
              <td>To investigate determinants of high use of the intervention; randomized controlled intervention (303)</td>
              <td>Sweden; information and communication and arts, entertainment, and recreation; N/R</td>
              <td>N/R; assess, monitor, and promote; workplace stress</td>
              <td>Web-based</td>
            </tr>
          </tbody>
        </table>
        <table-wrap-foot>
          <fn id="table1fn1">
            <p><sup>a</sup>Focused on implementation.</p>
          </fn>
          <fn id="table1fn2">
            <p><sup>b</sup>N/R: not reported.</p>
          </fn>
          <fn id="table1fn3">
            <p><sup>c</sup>N/A: not applicable.</p>
          </fn>
          <fn id="table1fn4">
            <p><sup>d</sup>N/S: not specified.</p>
          </fn>
          <fn id="table1fn5">
            <p><sup>e</sup>OeMH: occupational eMental health.</p>
          </fn>
        </table-wrap-foot>
      </table-wrap>
      <fig id="figure1" position="float">
        <label>Figure 1</label>
        <caption>
          <p>PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) flowchart of the review search, selection, and inclusion process.</p>
        </caption>
        <graphic xlink:href="jmir_v24i6e34479_fig1.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
      </fig>
      <sec>
        <title>Publication Characteristics</title>
        <p>The 31 included publications comprised 28 journal articles [<xref ref-type="bibr" rid="ref36">36</xref>-<xref ref-type="bibr" rid="ref45">45</xref>,<xref ref-type="bibr" rid="ref47">47</xref>,<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref50">50</xref>-<xref ref-type="bibr" rid="ref57">57</xref>,<xref ref-type="bibr" rid="ref59">59</xref>-<xref ref-type="bibr" rid="ref63">63</xref>], 2 book chapters [<xref ref-type="bibr" rid="ref8">8</xref>,<xref ref-type="bibr" rid="ref64">64</xref>], and a doctoral dissertation [<xref ref-type="bibr" rid="ref46">46</xref>] (<xref ref-type="table" rid="table1">Tables 1</xref> and <xref ref-type="table" rid="table2">2</xref>). Most (25/31, 81%) [<xref ref-type="bibr" rid="ref8">8</xref>,<xref ref-type="bibr" rid="ref36">36</xref>-<xref ref-type="bibr" rid="ref47">47</xref>,<xref ref-type="bibr" rid="ref49">49</xref>-<xref ref-type="bibr" rid="ref59">59</xref>] of the included articles were published between 2015 and 2021 and were mainly primary studies (23/31, 74%) [<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref39">39</xref>,<xref ref-type="bibr" rid="ref41">41</xref>-<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref53">53</xref>,<xref ref-type="bibr" rid="ref54">54</xref>,<xref ref-type="bibr" rid="ref56">56</xref>-<xref ref-type="bibr" rid="ref58">58</xref>,<xref ref-type="bibr" rid="ref60">60</xref>-<xref ref-type="bibr" rid="ref63">63</xref>,<xref ref-type="bibr" rid="ref65">65</xref>]. Of the 31 included publications on OeMH interventions, 14 (45%) focused on their implementation [<xref ref-type="bibr" rid="ref8">8</xref>,<xref ref-type="bibr" rid="ref37">37</xref>,<xref ref-type="bibr" rid="ref38">38</xref>,<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref41">41</xref>,<xref ref-type="bibr" rid="ref49">49</xref>-<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref53">53</xref>,<xref ref-type="bibr" rid="ref54">54</xref>,<xref ref-type="bibr" rid="ref62">62</xref>-<xref ref-type="bibr" rid="ref64">64</xref>] and 17 (55%) did not focus on their implementation but had results or noted implications related to their implementation [<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref39">39</xref>,<xref ref-type="bibr" rid="ref42">42</xref>-<xref ref-type="bibr" rid="ref47">47</xref>,<xref ref-type="bibr" rid="ref52">52</xref>,<xref ref-type="bibr" rid="ref55">55</xref>-<xref ref-type="bibr" rid="ref61">61</xref>,<xref ref-type="bibr" rid="ref65">65</xref>].</p>
        <table-wrap position="float" id="table2">
          <label>Table 2</label>
          <caption>
            <p>Summary of study characteristics (N=31).</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="30"/>
            <col width="690"/>
            <col width="280"/>
            <thead>
              <tr valign="top">
                <td colspan="2">Characteristics and citations</td>
                <td>Frequency, n (%)</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td colspan="3">
                  <bold>Publication type</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Book chapter [<xref ref-type="bibr" rid="ref8">8</xref>,<xref ref-type="bibr" rid="ref64">64</xref>]</td>
                <td>2 (6)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Doctoral dissertation [<xref ref-type="bibr" rid="ref46">46</xref>]</td>
                <td>1 (3)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Journal article [<xref ref-type="bibr" rid="ref36">36</xref>-<xref ref-type="bibr" rid="ref45">45</xref>,<xref ref-type="bibr" rid="ref47">47</xref>,<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref50">50</xref>-<xref ref-type="bibr" rid="ref57">57</xref>,<xref ref-type="bibr" rid="ref59">59</xref>-<xref ref-type="bibr" rid="ref63">63</xref>]</td>
                <td>28 (90)</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Publication year</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>2010 [<xref ref-type="bibr" rid="ref65">65</xref>]</td>
                <td>1 (3)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>2013 [<xref ref-type="bibr" rid="ref64">64</xref>]</td>
                <td>1 (3)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>2014 [<xref ref-type="bibr" rid="ref61">61</xref>-<xref ref-type="bibr" rid="ref63">63</xref>]</td>
                <td>3 (10)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>2015 [<xref ref-type="bibr" rid="ref60">60</xref>]</td>
                <td>1 (3)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>2016 [<xref ref-type="bibr" rid="ref8">8</xref>,<xref ref-type="bibr" rid="ref56">56</xref>-<xref ref-type="bibr" rid="ref59">59</xref>]</td>
                <td>5 (16)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>2017 [<xref ref-type="bibr" rid="ref54">54</xref>,<xref ref-type="bibr" rid="ref55">55</xref>]</td>
                <td>2 (6)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>2018 [<xref ref-type="bibr" rid="ref45">45</xref>-<xref ref-type="bibr" rid="ref53">53</xref>]</td>
                <td>9 (29)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>2019 [<xref ref-type="bibr" rid="ref42">42</xref>-<xref ref-type="bibr" rid="ref44">44</xref>]</td>
                <td>3 (10)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>2020 [<xref ref-type="bibr" rid="ref36">36</xref>-<xref ref-type="bibr" rid="ref41">41</xref>]</td>
                <td>6 (19)</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Study type</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Narrative literature review [<xref ref-type="bibr" rid="ref8">8</xref>,<xref ref-type="bibr" rid="ref65">65</xref>]</td>
                <td>2 (6)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Pilot [<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref52">52</xref>,<xref ref-type="bibr" rid="ref55">55</xref>]</td>
                <td>3 (10)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Primary study [<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref39">39</xref>,<xref ref-type="bibr" rid="ref41">41</xref>-<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref53">53</xref>,<xref ref-type="bibr" rid="ref54">54</xref>,<xref ref-type="bibr" rid="ref56">56</xref>-<xref ref-type="bibr" rid="ref58">58</xref>,<xref ref-type="bibr" rid="ref60">60</xref>-<xref ref-type="bibr" rid="ref63">63</xref>,<xref ref-type="bibr" rid="ref65">65</xref>]</td>
                <td>23 (74)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Protocol [<xref ref-type="bibr" rid="ref37">37</xref>,<xref ref-type="bibr" rid="ref38">38</xref>,<xref ref-type="bibr" rid="ref59">59</xref>]</td>
                <td>3 (10)</td>
              </tr>
            </tbody>
          </table>
        </table-wrap>
      </sec>
      <sec>
        <title>Intervention Characteristics</title>
        <p>A total of 24 interventions were reported in 27 studies [<xref ref-type="bibr" rid="ref36">36</xref>-<xref ref-type="bibr" rid="ref46">46</xref>,<xref ref-type="bibr" rid="ref49">49</xref>,<xref ref-type="bibr" rid="ref51">51</xref>-<xref ref-type="bibr" rid="ref56">56</xref>,<xref ref-type="bibr" rid="ref58">58</xref>-<xref ref-type="bibr" rid="ref65">65</xref>] (<xref ref-type="table" rid="table3">Table 3</xref>). These interventions were largely web-based (n=16, 67%%) [<xref ref-type="bibr" rid="ref41">41</xref>-<xref ref-type="bibr" rid="ref46">46</xref>,<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref49">49</xref>,<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref53">53</xref>-<xref ref-type="bibr" rid="ref55">55</xref>,<xref ref-type="bibr" rid="ref60">60</xref>-<xref ref-type="bibr" rid="ref65">65</xref>] and most aimed to improve (n=19, 79%) [<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref37">37</xref>,<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref42">42</xref>-<xref ref-type="bibr" rid="ref46">46</xref>,<xref ref-type="bibr" rid="ref49">49</xref>,<xref ref-type="bibr" rid="ref51">51</xref>-<xref ref-type="bibr" rid="ref56">56</xref>,<xref ref-type="bibr" rid="ref58">58</xref>-<xref ref-type="bibr" rid="ref63">63</xref>] and, to a lesser extent, educate users about mental health problems. Most interventions have focused on stress-related disorders and symptoms (n=17, 71%) [<xref ref-type="bibr" rid="ref8">8</xref>,<xref ref-type="bibr" rid="ref36">36</xref>-<xref ref-type="bibr" rid="ref47">47</xref>,<xref ref-type="bibr" rid="ref49">49</xref>-<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref53">53</xref>-<xref ref-type="bibr" rid="ref63">63</xref>,<xref ref-type="bibr" rid="ref65">65</xref>], but a wide range of mental health problems (eg, burnout, anxiety disorders, and substance-related disorders) have also been covered to some extent. Where reported [<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref38">38</xref>,<xref ref-type="bibr" rid="ref41">41</xref>,<xref ref-type="bibr" rid="ref43">43</xref>-<xref ref-type="bibr" rid="ref46">46</xref>,<xref ref-type="bibr" rid="ref49">49</xref>,<xref ref-type="bibr" rid="ref51">51</xref>-<xref ref-type="bibr" rid="ref53">53</xref>,<xref ref-type="bibr" rid="ref55">55</xref>,<xref ref-type="bibr" rid="ref56">56</xref>,<xref ref-type="bibr" rid="ref58">58</xref>-<xref ref-type="bibr" rid="ref65">65</xref>], these interventions (n=19, 79%) largely targeted employees in professional occupations (eg, teachers and physicians). Most of these interventions were made available in specific countries, mainly in Europe (n=15, 63%%) [<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref38">38</xref>,<xref ref-type="bibr" rid="ref39">39</xref>,<xref ref-type="bibr" rid="ref41">41</xref>,<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref45">45</xref>,<xref ref-type="bibr" rid="ref49">49</xref>,<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref53">53</xref>-<xref ref-type="bibr" rid="ref56">56</xref>,<xref ref-type="bibr" rid="ref59">59</xref>,<xref ref-type="bibr" rid="ref61">61</xref>-<xref ref-type="bibr" rid="ref65">65</xref>], except for one that was available internationally (n=1, 4%) [<xref ref-type="bibr" rid="ref64">64</xref>]. Standardized information about these 24 interventions, including year of launch, language, number of employees and employers interested in and who adopted the app, organizational size, and internal policies, was not clearly reported where relevant and could not be accurately extracted in detail.</p>
        <table-wrap position="float" id="table3">
          <label>Table 3</label>
          <caption>
            <p>Summary of intervention characteristics (N=24).</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="30"/>
            <col width="730"/>
            <col width="240"/>
            <thead>
              <tr valign="top">
                <td colspan="2">Characteristics and citations</td>
                <td>Frequency, n (%)</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td colspan="3">
                  <bold>Technology</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Smartphone [<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref39">39</xref>,<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref52">52</xref>,<xref ref-type="bibr" rid="ref56">56</xref>]</td>
                <td>5 (21)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Web [<xref ref-type="bibr" rid="ref41">41</xref>-<xref ref-type="bibr" rid="ref46">46</xref>,<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref49">49</xref>,<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref53">53</xref>-<xref ref-type="bibr" rid="ref55">55</xref>,<xref ref-type="bibr" rid="ref60">60</xref>-<xref ref-type="bibr" rid="ref65">65</xref>]</td>
                <td>16 (67)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Web and smartphone [<xref ref-type="bibr" rid="ref37">37</xref>]</td>
                <td>1 (4)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Web and telephone [<xref ref-type="bibr" rid="ref38">38</xref>]</td>
                <td>1 (4)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Email [<xref ref-type="bibr" rid="ref58">58</xref>]</td>
                <td>1 (4)</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Aim</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Assess [<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref49">49</xref>,<xref ref-type="bibr" rid="ref62">62</xref>,<xref ref-type="bibr" rid="ref65">65</xref>]</td>
                <td>4 (17)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Educate [<xref ref-type="bibr" rid="ref55">55</xref>,<xref ref-type="bibr" rid="ref59">59</xref>]</td>
                <td>1 (4)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Improve [<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref37">37</xref>,<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref42">42</xref>-<xref ref-type="bibr" rid="ref46">46</xref>,<xref ref-type="bibr" rid="ref49">49</xref>,<xref ref-type="bibr" rid="ref51">51</xref>-<xref ref-type="bibr" rid="ref56">56</xref>,<xref ref-type="bibr" rid="ref58">58</xref>-<xref ref-type="bibr" rid="ref63">63</xref>]</td>
                <td>19 (79)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Manage [<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref41">41</xref>,<xref ref-type="bibr" rid="ref47">47</xref>,<xref ref-type="bibr" rid="ref56">56</xref>,<xref ref-type="bibr" rid="ref64">64</xref>]</td>
                <td>5 (21)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Monitor [<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref54">54</xref>,<xref ref-type="bibr" rid="ref55">55</xref>,<xref ref-type="bibr" rid="ref59">59</xref>,<xref ref-type="bibr" rid="ref62">62</xref>,<xref ref-type="bibr" rid="ref65">65</xref>]</td>
                <td>6 (25)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Prevent [<xref ref-type="bibr" rid="ref38">38</xref>,<xref ref-type="bibr" rid="ref49">49</xref>,<xref ref-type="bibr" rid="ref63">63</xref>,<xref ref-type="bibr" rid="ref64">64</xref>]</td>
                <td>4 (17)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Promote [<xref ref-type="bibr" rid="ref43">43</xref>,<xref ref-type="bibr" rid="ref45">45</xref>,<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref58">58</xref>,<xref ref-type="bibr" rid="ref62">62</xref>,<xref ref-type="bibr" rid="ref64">64</xref>,<xref ref-type="bibr" rid="ref65">65</xref>]</td>
                <td>7 (29)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Support [<xref ref-type="bibr" rid="ref39">39</xref>,<xref ref-type="bibr" rid="ref41">41</xref>,<xref ref-type="bibr" rid="ref51">51</xref>]</td>
                <td>3 (13)</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Target mental health problem</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Anxiety disorders and symptoms [<xref ref-type="bibr" rid="ref37">37</xref>,<xref ref-type="bibr" rid="ref38">38</xref>]</td>
                <td>2 (8)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Burnout [<xref ref-type="bibr" rid="ref46">46</xref>]</td>
                <td>1 (4)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Chronic pain [<xref ref-type="bibr" rid="ref38">38</xref>]</td>
                <td>1 (4)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Common mental disorders [<xref ref-type="bibr" rid="ref39">39</xref>]</td>
                <td>1 (4)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Mood disorders and symptoms [<xref ref-type="bibr" rid="ref37">37</xref>,<xref ref-type="bibr" rid="ref38">38</xref>,<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref52">52</xref>,<xref ref-type="bibr" rid="ref57">57</xref>,<xref ref-type="bibr" rid="ref61">61</xref>,<xref ref-type="bibr" rid="ref63">63</xref>]</td>
                <td>8 (33)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Return to work [<xref ref-type="bibr" rid="ref54">54</xref>]</td>
                <td>1 (4)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Sleep problems [<xref ref-type="bibr" rid="ref38">38</xref>,<xref ref-type="bibr" rid="ref45">45</xref>,<xref ref-type="bibr" rid="ref58">58</xref>]</td>
                <td>3 (13)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Substance-related and addictive disorders [<xref ref-type="bibr" rid="ref38">38</xref>,<xref ref-type="bibr" rid="ref60">60</xref>]</td>
                <td>2 (8)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Stigma and discrimination [<xref ref-type="bibr" rid="ref44">44</xref>]</td>
                <td>1 (4)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Stress-related disorders and symptoms [<xref ref-type="bibr" rid="ref8">8</xref>,<xref ref-type="bibr" rid="ref36">36</xref>-<xref ref-type="bibr" rid="ref47">47</xref>,<xref ref-type="bibr" rid="ref49">49</xref>-<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref53">53</xref>-<xref ref-type="bibr" rid="ref63">63</xref>,<xref ref-type="bibr" rid="ref65">65</xref>]</td>
                <td>17 (71)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Well-being problems [<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref41">41</xref>,<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref54">54</xref>,<xref ref-type="bibr" rid="ref62">62</xref>,<xref ref-type="bibr" rid="ref64">64</xref>]</td>
                <td>7 (29)</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Country of implementation</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Australia [<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref52">52</xref>]</td>
                <td>2 (8)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Canada [<xref ref-type="bibr" rid="ref43">43</xref>]</td>
                <td>1 (4)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>China [<xref ref-type="bibr" rid="ref37">37</xref>]</td>
                <td>1 (4)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Germany [<xref ref-type="bibr" rid="ref38">38</xref>,<xref ref-type="bibr" rid="ref56">56</xref>]</td>
                <td>2 (8)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>International [<xref ref-type="bibr" rid="ref64">64</xref>]</td>
                <td>1 (4)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>The Netherlands [<xref ref-type="bibr" rid="ref49">49</xref>,<xref ref-type="bibr" rid="ref54">54</xref>,<xref ref-type="bibr" rid="ref63">63</xref>]</td>
                <td>3 (13)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>New Zealand [<xref ref-type="bibr" rid="ref44">44</xref>]</td>
                <td>1 (4)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Sweden [<xref ref-type="bibr" rid="ref39">39</xref>,<xref ref-type="bibr" rid="ref45">45</xref>,<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref62">62</xref>,<xref ref-type="bibr" rid="ref65">65</xref>]</td>
                <td>5 (21)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>United Kingdom [<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref41">41</xref>,<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref53">53</xref>,<xref ref-type="bibr" rid="ref55">55</xref>,<xref ref-type="bibr" rid="ref59">59</xref>,<xref ref-type="bibr" rid="ref61">61</xref>]</td>
                <td>5 (21)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>United States [<xref ref-type="bibr" rid="ref43">43</xref>,<xref ref-type="bibr" rid="ref46">46</xref>,<xref ref-type="bibr" rid="ref58">58</xref>,<xref ref-type="bibr" rid="ref60">60</xref>]</td>
                <td>4 (17)</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Target occupational groups</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Armed forces occupations [<xref ref-type="bibr" rid="ref44">44</xref>,<xref ref-type="bibr" rid="ref60">60</xref>]</td>
                <td>2 (8)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Clerical support worker [<xref ref-type="bibr" rid="ref45">45</xref>,<xref ref-type="bibr" rid="ref55">55</xref>,<xref ref-type="bibr" rid="ref61">61</xref>,<xref ref-type="bibr" rid="ref62">62</xref>]</td>
                <td>4 (17)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Elementary occupations (eg, cleaners and laborers) [<xref ref-type="bibr" rid="ref45">45</xref>]</td>
                <td>1 (4)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Managers (eg, chief executive officer) [<xref ref-type="bibr" rid="ref41">41</xref>,<xref ref-type="bibr" rid="ref55">55</xref>,<xref ref-type="bibr" rid="ref61">61</xref>]</td>
                <td>3 (13)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Not reported [<xref ref-type="bibr" rid="ref37">37</xref>,<xref ref-type="bibr" rid="ref39">39</xref>,<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref54">54</xref>]</td>
                <td>5 (21)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Plant and machine operators and assemblers [<xref ref-type="bibr" rid="ref61">61</xref>]</td>
                <td>1 (4)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Professionals (eg, teachers and physicians) [<xref ref-type="bibr" rid="ref41">41</xref>,<xref ref-type="bibr" rid="ref43">43</xref>,<xref ref-type="bibr" rid="ref45">45</xref>,<xref ref-type="bibr" rid="ref46">46</xref>,<xref ref-type="bibr" rid="ref49">49</xref>,<xref ref-type="bibr" rid="ref55">55</xref>,<xref ref-type="bibr" rid="ref58">58</xref>,<xref ref-type="bibr" rid="ref61">61</xref>-<xref ref-type="bibr" rid="ref63">63</xref>]</td>
                <td>10 (42)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Service and sales workers [<xref ref-type="bibr" rid="ref45">45</xref>,<xref ref-type="bibr" rid="ref61">61</xref>,<xref ref-type="bibr" rid="ref65">65</xref>]</td>
                <td>3 (13)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Social workers (ie, specifically child and family social workers) [<xref ref-type="bibr" rid="ref36">36</xref>]</td>
                <td>1 (4)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Skilled agricultural, forestry, and fishery workers [<xref ref-type="bibr" rid="ref38">38</xref>,<xref ref-type="bibr" rid="ref61">61</xref>]</td>
                <td>2 (8)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Technicians and associate professionals [<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref41">41</xref>,<xref ref-type="bibr" rid="ref55">55</xref>,<xref ref-type="bibr" rid="ref61">61</xref>,<xref ref-type="bibr" rid="ref62">62</xref>,<xref ref-type="bibr" rid="ref65">65</xref>]</td>
                <td>6 (25)</td>
              </tr>
            </tbody>
          </table>
        </table-wrap>
      </sec>
      <sec>
        <title>Implementation Strategies</title>
        <sec>
          <title>Overview</title>
          <p>Overall, 98 examples of implementation strategies were identified (<xref ref-type="supplementary-material" rid="app2">Multimedia Appendix 2</xref>). <xref ref-type="table" rid="table4">Table 4</xref> categorizes these strategies into 17 discrete implementation strategies and maps them onto relevant RE-AIM domains based on the perceived intent of the themes. Each discrete implementation strategy is reported with the percentage and absolute number of defining strategy examples in relation to the 98 examples. Although evaluating effectiveness strategies is beyond the scope of this review, relevant effectiveness data could not be presented as they were largely absent or incomplete.</p>
          <p>A total of 36 examples of implementation strategies were extracted from publications that focused on the implementation of OeMH interventions, and 62 from publications that reported results or noted implications related to their implementation. There were no notable differences other than the larger number of examples extracted from the latter group so strategy examples would not be reported separately. Most strategy examples were organized under implementation (61/98, 62%), followed by reach (27/98, 28%), effectiveness (19/98), adoption (17/98, 17%), and maintenance (8/98, 8%). A couple of strategy examples were organized into multiple domains (6/98, 6%). The following sections provide a descriptive summary of the strategy examples categorized in each RE-AIM domain.</p>
          <table-wrap position="float" id="table4">
            <label>Table 4</label>
            <caption>
              <p>Discrete implementation strategies mapped to relevant RE-AIM (reach, effectiveness, adoption, implementation, and maintenance) domains (N=98).</p>
            </caption>
            <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
              <col width="330"/>
              <col width="440"/>
              <col width="230"/>
              <thead>
                <tr valign="top">
                  <td>Discrete implementation strategies—proportion of strategy examples; n (%)</td>
                  <td>Example strategy</td>
                  <td>Relevant RE-AIM domains</td>
                </tr>
              </thead>
              <tbody>
                <tr valign="top">
                  <td>Develop and organize implementation quality monitoring systems and act on insights in a timely manner where feasible; 17 (17)</td>
                  <td>Improve maintenance and adherence through the timely presentation of findings from monthly user feedback surveys where after follow-up actions can be immediately applied to the intervention [<xref ref-type="bibr" rid="ref64">64</xref>]</td>
                  <td>Effectiveness, implementation, and maintenance</td>
                </tr>
                <tr valign="top">
                  <td>Assess for readiness and tailor strategies to address identified barriers and benefit from facilitators; 13 (13)</td>
                  <td>Filled knowledge gaps surrounding the effectiveness of eMental health interventions in the workplace by conducting systematic reviews on relevant topics [<xref ref-type="bibr" rid="ref52">52</xref>]</td>
                  <td>Reach, effectiveness, implementation, and maintenance</td>
                </tr>
                <tr valign="top">
                  <td>Use mass media to increase reach; 9 (9)</td>
                  <td>Users were recruited by sharing information about the intervention through advertisements distributed via email and the organizations’ intranet and magazine [<xref ref-type="bibr" rid="ref59">59</xref>]</td>
                  <td>Reach</td>
                </tr>
                <tr valign="top">
                  <td>Capture local knowledge from implementation sites and involve users early in the implementation and intervention development effort; 8 (8)</td>
                  <td>A consultation process was carried out with users, clinical psychologists, psychiatrists, information technology professionals, and design and user experience specialists to ensure the app’s content and design appealed to a broad range of workers from different industries [<xref ref-type="bibr" rid="ref40">40</xref>]</td>
                  <td>Reach, effectiveness, adoption, implementation, and maintenance</td>
                </tr>
                <tr valign="top">
                  <td>Promote adaptability in the intervention to meet local needs without compromising fidelity; 8 (8)</td>
                  <td>Interventions were improved and adapted to each participating organization based on user feedback [<xref ref-type="bibr" rid="ref36">36</xref>]</td>
                  <td>Reach, effectiveness, adoption, implementation, and maintenance</td>
                </tr>
                <tr valign="top">
                  <td>Send reminders; 7 (7)</td>
                  <td>Automatic email reminders were sent based on user-determined intervals and user inactivity [<xref ref-type="bibr" rid="ref45">45</xref>]</td>
                  <td>Implementation</td>
                </tr>
                <tr valign="top">
                  <td>Provide support to users during the intervention; 6 (6)</td>
                  <td>Users were able to contact the intervention coach at any time to ask for feedback, additional help, or advice and the coach would respond within 24 hours [<xref ref-type="bibr" rid="ref59">59</xref>]</td>
                  <td>Implementation</td>
                </tr>
                <tr valign="top">
                  <td>Conduct educational meetings; 5 (5)</td>
                  <td>Senior and middle management–led introductory seminars with employees that aimed to explain the intervention, secure acceptance, provide answers to questions, and inspire their participation [<xref ref-type="bibr" rid="ref64">64</xref>]</td>
                  <td>Reach, adoption, and implementation</td>
                </tr>
                <tr valign="top">
                  <td>Provide incentives; 5 (5)</td>
                  <td>Users received a certificate of completion and the training was recognized as continuing education toward the renewal of their professional certification [<xref ref-type="bibr" rid="ref43">43</xref>]</td>
                  <td>Reach and implementation</td>
                </tr>
                <tr valign="top">
                  <td>Identify and prepare organizational champions who will dedicate themselves to supporting, marketing, and driving the implementation; 4 (4)</td>
                  <td>Identification of champions at the implementation site facilitated organizational and employee buy-in [<xref ref-type="bibr" rid="ref46">46</xref>]</td>
                  <td>Reach, adoption, implementation, and maintenance</td>
                </tr>
                <tr valign="top">
                  <td>Involve senior management; 4 (4)</td>
                  <td>The program was developed as a quality improvement project by the hospital and all research procedures (ie, retrospectively reviewing these outcomes) were approved by the institutional review board at the hospital [<xref ref-type="bibr" rid="ref58">58</xref>]</td>
                  <td>Reach, adoption, implementation, and maintenance</td>
                </tr>
                <tr valign="top">
                  <td>Provide opportunities for users to obtain feedback on progress; 4 (4)</td>
                  <td>Participants received immediate and automatic tailored feedback and could monitor their own responses and trends over time [<xref ref-type="bibr" rid="ref45">45</xref>]</td>
                  <td>Implementation</td>
                </tr>
                <tr valign="top">
                  <td>Stage implementation scale-up; 4 (4)</td>
                  <td>Conducted a pilot study aimed at assessing the usability, feasibility, acceptability, and preliminary effects of an app-based intervention designed to target depressive symptoms in a stressed working population [<xref ref-type="bibr" rid="ref55">55</xref>]</td>
                  <td>Effectiveness and implementation</td>
                </tr>
                <tr valign="top">
                  <td>Customize recruitment activities to enhance reach; 3 (3)</td>
                  <td>When recruitment efforts did not attract enough participants, executives with the largest workforces in the region and industry were contacted directly via telephone and offered enrollment [<xref ref-type="bibr" rid="ref45">45</xref>]</td>
                  <td>Reach and adoption</td>
                </tr>
                <tr valign="top">
                  <td>Develop and distribute educational materials; 3 (3)</td>
                  <td>All participants who returned the consent form received an email welcoming them to the study and explaining how to log in and use their personal webpage for the stress management program [<xref ref-type="bibr" rid="ref65">65</xref>]</td>
                  <td>Reach, adoption, and implementation</td>
                </tr>
                <tr valign="top">
                  <td>Provide immediate opportunities to demonstrate commitment; 3 (3)</td>
                  <td>Management representatives were offered spots to enroll their organizations immediately after educational meetings about the intervention or to enroll at a later time [<xref ref-type="bibr" rid="ref45">45</xref>]</td>
                  <td>Reach and adoption</td>
                </tr>
                <tr valign="top">
                  <td>Use advisory boards and workgroups to provide input and advice on implementation and improvements; 3 (3)</td>
                  <td>Systematic feedback was sought from researchers, expert clinicians, and veterans on the program and its content [<xref ref-type="bibr" rid="ref60">60</xref>]</td>
                  <td>Implementation</td>
                </tr>
              </tbody>
            </table>
          </table-wrap>
        </sec>
        <sec>
          <title>Reach</title>
          <p>Mass media services were mainly used to increase reach (9/27, 33%). Examples include email [<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref43">43</xref>,<xref ref-type="bibr" rid="ref46">46</xref>,<xref ref-type="bibr" rid="ref52">52</xref>,<xref ref-type="bibr" rid="ref58">58</xref>,<xref ref-type="bibr" rid="ref59">59</xref>,<xref ref-type="bibr" rid="ref63">63</xref>], industry publications [<xref ref-type="bibr" rid="ref43">43</xref>,<xref ref-type="bibr" rid="ref59">59</xref>], targeted web-based advertisements (eg, Facebook) [<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref52">52</xref>], and the organizations’ intranet [<xref ref-type="bibr" rid="ref59">59</xref>,<xref ref-type="bibr" rid="ref61">61</xref>,<xref ref-type="bibr" rid="ref63">63</xref>]. The provision of attractive incentives for participation (5/27, 19%) included monetary remuneration [<xref ref-type="bibr" rid="ref60">60</xref>], vouchers [<xref ref-type="bibr" rid="ref40">40</xref>], points for employee reward schemes [<xref ref-type="bibr" rid="ref58">58</xref>], educational credits for professional certifications [<xref ref-type="bibr" rid="ref43">43</xref>], and additional medical benefits [<xref ref-type="bibr" rid="ref65">65</xref>]. Other strategies included engaging potential users through educational meetings [<xref ref-type="bibr" rid="ref62">62</xref>] and materials [<xref ref-type="bibr" rid="ref65">65</xref>] (2/27, 7%), employees tasked with the responsibility of supporting the implementation of the intervention [<xref ref-type="bibr" rid="ref46">46</xref>,<xref ref-type="bibr" rid="ref61">61</xref>] (2/27, 7%), and well-timed opportunities to commit [<xref ref-type="bibr" rid="ref64">64</xref>,<xref ref-type="bibr" rid="ref65">65</xref>] (2/27, 7%). Local barriers to increasing reach among target users were identified through consultations with implementation sites, eligible users, and literature [<xref ref-type="bibr" rid="ref52">52</xref>,<xref ref-type="bibr" rid="ref61">61</xref>,<xref ref-type="bibr" rid="ref64">64</xref>] (3/27, 11%), and recruitment activities were later modified to avoid or overcome these barriers where possible [<xref ref-type="bibr" rid="ref63">63</xref>] (4/27, 15%).</p>
        </sec>
        <sec>
          <title>Effectiveness</title>
          <p>Strategies to improve the effectiveness of the intervention mainly relied on insights obtained from a diverse group of professionals in relevant fields, representatives of implementation sites, target users, and intervention use data (12/19, 63%). This insight was captured through stakeholder consultations [<xref ref-type="bibr" rid="ref41">41</xref>], steering group interviews and focus groups with target users [<xref ref-type="bibr" rid="ref36">36</xref>], peer review panels [<xref ref-type="bibr" rid="ref41">41</xref>], and user experience research [<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref37">37</xref>,<xref ref-type="bibr" rid="ref41">41</xref>,<xref ref-type="bibr" rid="ref52">52</xref>,<xref ref-type="bibr" rid="ref53">53</xref>,<xref ref-type="bibr" rid="ref63">63</xref>] throughout the implementation process. Several strategies adopted an incremental approach to implementation [<xref ref-type="bibr" rid="ref52">52</xref>,<xref ref-type="bibr" rid="ref55">55</xref>,<xref ref-type="bibr" rid="ref59">59</xref>] (3/19, 16%), fostered adaptability in the intervention to adequately meet the local needs [<xref ref-type="bibr" rid="ref60">60</xref>] (2/19, 11%), or implemented measures to avoid or mitigate identified barriers that could negatively impact the effectiveness of the particular intervention [<xref ref-type="bibr" rid="ref49">49</xref>,<xref ref-type="bibr" rid="ref52">52</xref>] (2/19, 11%).</p>
        </sec>
        <sec>
          <title>Adoption</title>
          <p>Sharing and discussing details about the proposed intervention with decision-makers was the most commonly used adoption strategy. This involved conducting educational meetings [<xref ref-type="bibr" rid="ref45">45</xref>,<xref ref-type="bibr" rid="ref62">62</xref>,<xref ref-type="bibr" rid="ref64">64</xref>,<xref ref-type="bibr" rid="ref65">65</xref>] (4/17, 24%) and distributing educational materials about the intervention [<xref ref-type="bibr" rid="ref45">45</xref>] (1/17, 6%). Engaging senior management and others from the organization to identify necessary adaptations for intervention to succeed in the organization was also common. These strategies involved organizational stakeholders early in the intervention development process [<xref ref-type="bibr" rid="ref49">49</xref>,<xref ref-type="bibr" rid="ref64">64</xref>] (2/17, 12%) to adapt the intervention to meet special organizational needs without compromising fidelity [<xref ref-type="bibr" rid="ref64">64</xref>] (1/17, 6%) and address other identified barriers [<xref ref-type="bibr" rid="ref39">39</xref>] (1/17, 6%). Some strategies also identified staff members who could dedicate themselves to supporting, marketing, and driving the implementation within the organization, as this was expected to increase the likelihood of success [<xref ref-type="bibr" rid="ref46">46</xref>,<xref ref-type="bibr" rid="ref49">49</xref>] (2/17, 12%). The provision of immediate opportunities for decision-makers to confirm their commitment to adopt the intervention was also used [<xref ref-type="bibr" rid="ref45">45</xref>] (1/17, 6%).</p>
        </sec>
        <sec>
          <title>Implementation</title>
          <p>Implementation strategies focused on adapting interventions and customizing the implementation process to implementation settings, monitoring the consistency of delivery, and providing various forms of support as needed. Implementers underwent training, subscribed to a common protocol, and had their work reviewed to help ensure fidelity. Some implementation strategies were continuously monitored using both qualitative and quantitative methods, including surveys, implementation reviews, process evaluations, and other similar methods [<xref ref-type="bibr" rid="ref36">36</xref>-<xref ref-type="bibr" rid="ref38">38</xref>,<xref ref-type="bibr" rid="ref41">41</xref>,<xref ref-type="bibr" rid="ref49">49</xref>,<xref ref-type="bibr" rid="ref54">54</xref>,<xref ref-type="bibr" rid="ref56">56</xref>,<xref ref-type="bibr" rid="ref61">61</xref>,<xref ref-type="bibr" rid="ref63">63</xref>,<xref ref-type="bibr" rid="ref64">64</xref>] (16/61, 26%). A diverse group of stakeholders were involved in the assessments across the included studies. These assessments focused on measuring effectiveness, acceptability, and engagement [<xref ref-type="bibr" rid="ref36">36</xref>-<xref ref-type="bibr" rid="ref38">38</xref>,<xref ref-type="bibr" rid="ref41">41</xref>,<xref ref-type="bibr" rid="ref49">49</xref>,<xref ref-type="bibr" rid="ref54">54</xref>,<xref ref-type="bibr" rid="ref56">56</xref>,<xref ref-type="bibr" rid="ref61">61</xref>,<xref ref-type="bibr" rid="ref63">63</xref>,<xref ref-type="bibr" rid="ref64">64</xref>] (16/61, 26%). Findings were regularly applied quickly to overcome identified barriers and improve ongoing implementation processes [<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref60">60</xref>,<xref ref-type="bibr" rid="ref63">63</xref>,<xref ref-type="bibr" rid="ref64">64</xref>] (10/61, 16%). Some support options included a reminder feature (7/61, 11%) where users could set their own reminder notifications [<xref ref-type="bibr" rid="ref46">46</xref>] and be notified when their participation level was too low [<xref ref-type="bibr" rid="ref45">45</xref>,<xref ref-type="bibr" rid="ref56">56</xref>,<xref ref-type="bibr" rid="ref63">63</xref>] or when new updates became available [<xref ref-type="bibr" rid="ref43">43</xref>,<xref ref-type="bibr" rid="ref46">46</xref>].</p>
        </sec>
        <sec>
          <title>Maintenance</title>
          <p>Maintenance strategies involved changes at the organizational level, where accommodating work conditions [<xref ref-type="bibr" rid="ref43">43</xref>,<xref ref-type="bibr" rid="ref55">55</xref>] (2/8, 25%) and support staff [<xref ref-type="bibr" rid="ref58">58</xref>] (1/8, 13%) were sometimes arranged. Embedding interventions within existing employee programs was also expected to help sustain the use of the intervention [<xref ref-type="bibr" rid="ref58">58</xref>] (1/8, 13%). Special monitoring measures (eg, postintervention acceptability surveys and opportunities for monthly user feedback) were also established to provide insight into how benefits to users could be sustained after the initiative had officially ended [<xref ref-type="bibr" rid="ref37">37</xref>,<xref ref-type="bibr" rid="ref64">64</xref>] (2/8, 25%).</p>
        </sec>
      </sec>
      <sec>
        <title>Barriers and Facilitators</title>
        <sec>
          <title>Overview</title>
          <p>The included publications reported 114 barriers and 131 facilitation measures (<xref ref-type="supplementary-material" rid="app3">Multimedia Appendix 3</xref>), and 28 barriers were accompanied by facilitation measures. There were no notable differences between barriers and facilitators extracted from publications that focused on the implementation of OeMH interventions (108/217, 49.8%) or that reported results or noted implications related to their implementation (109/217, 50.2%) so these will be reported together. Examples of barriers and facilitators organized by the relevant CFIR domains and associated constructs are provided in the corresponding tables. Most of the 217 identified barriers and facilitation measures were related to key attributes of interventions that influence successful implementation (103/217, 47.5%), followed by the inner setting of the organization (87/217, 40.1%), individual characteristics of target users (25/217, 11.5%), and the outer setting of the organization (2/217, 0.9%). The highest number of barriers were categorized under the inner setting (54/114, 47.4%), followed by intervention characteristics (35/114, 30.7%), individual characteristics of target users (22/114, 19.3%), and the outer setting of the organization (2/114, 1.8%) domains. The highest number of facilitators were categorized under intervention characteristics (77/131, 58.8%), followed by inner setting (44/131, 33.6%), individual characteristics of target users (9/131, 6.9%), and outer setting of the organization (1/131, 0.8%) domains.</p>
        </sec>
        <sec>
          <title>Intervention Characteristics</title>
          <p>Numerous barriers and facilitators were identified regarding how the interventions were bundled, presented, and assembled (ie, design quality and packaging) (<xref ref-type="table" rid="table5">Table 5</xref>). Participants from several studies considered web-based platforms to be an impersonal medium (eg, no face-to-face contact or human interaction) [<xref ref-type="bibr" rid="ref53">53</xref>,<xref ref-type="bibr" rid="ref57">57</xref>,<xref ref-type="bibr" rid="ref61">61</xref>], and some saw its use as inappropriate for helping with sensitive topics such as mental health problems [<xref ref-type="bibr" rid="ref44">44</xref>]. Several usability issues (eg, poor accessibility, technical issues, unclear navigational elements and user interface, and overly effortful tasks) have also emerged as barriers [<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref52">52</xref>,<xref ref-type="bibr" rid="ref53">53</xref>,<xref ref-type="bibr" rid="ref60">60</xref>,<xref ref-type="bibr" rid="ref61">61</xref>,<xref ref-type="bibr" rid="ref64">64</xref>]. Accordingly, ensuring good usability [<xref ref-type="bibr" rid="ref8">8</xref>,<xref ref-type="bibr" rid="ref39">39</xref>,<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref53">53</xref>,<xref ref-type="bibr" rid="ref57">57</xref>,<xref ref-type="bibr" rid="ref64">64</xref>] and considering individual factors (eg, high impulsivity benefits from continuous motivational components) [<xref ref-type="bibr" rid="ref39">39</xref>,<xref ref-type="bibr" rid="ref45">45</xref>,<xref ref-type="bibr" rid="ref57">57</xref>,<xref ref-type="bibr" rid="ref65">65</xref>] in the design were also often reported as facilitators.</p>
          <p>The stakeholders’ perceptions of the evidence supporting the effectiveness of the proposed occupational mental interventions were influenced by several factors. The barriers included between-group contamination due to limited randomization at the individual level, unrepresentativeness of samples used for the general workforce, use of new or adapted measures with low reliability [<xref ref-type="bibr" rid="ref55">55</xref>], and type 1 errors [<xref ref-type="bibr" rid="ref58">58</xref>]. Identified facilitators focused on the including diverse samples (eg, including underrepresented industries and occupations) [<xref ref-type="bibr" rid="ref55">55</xref>], collecting comparable demographic data [<xref ref-type="bibr" rid="ref55">55</xref>], including comprehensive engagement measures [<xref ref-type="bibr" rid="ref55">55</xref>], presenting interventions based on credible information highly relevant to target employees [<xref ref-type="bibr" rid="ref57">57</xref>], using control conditions when evaluating effectiveness [<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref58">58</xref>], providing evidence from similar interventions that demonstrate effectiveness [<xref ref-type="bibr" rid="ref65">65</xref>], and conducting comprehensive and ongoing process evaluations to inform implementation [<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref63">63</xref>].</p>
          <table-wrap position="float" id="table5">
            <label>Table 5</label>
            <caption>
              <p>Examples of barriers and facilitators organized under the intervention characteristics Consolidated Framework for Implementation Research domain (N=217).</p>
            </caption>
            <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
              <col width="380"/>
              <col width="310"/>
              <col width="310"/>
              <thead>
                <tr valign="top">
                  <td>Relevant associated construct—proportion of barriers and facilitators; n (%) and brief description</td>
                  <td>Example of identified barriers</td>
                  <td>Example of identified facilitators</td>
                </tr>
              </thead>
              <tbody>
                <tr valign="top">
                  <td>Evidence strength and quality; 15 (6.9); stakeholders’ perceptions of the quality and validity of evidence supporting the belief that the intervention will have desired outcomes</td>
                  <td>Using newly created or adapted measures demonstrating low reliability negatively impacts the strength of findings [<xref ref-type="bibr" rid="ref55">55</xref>]</td>
                  <td>Providing evidence from other programs and interventions could be a strategy (oral presentations or reading materials) to demonstrate likely effectiveness [<xref ref-type="bibr" rid="ref65">65</xref>]</td>
                </tr>
                <tr valign="top">
                  <td>Relative advantage; 2 (0.9); stakeholders’ perception of the advantage of implementing the intervention versus an alternative solution</td>
                  <td>Possible low motivation from employers and organization in their employees return to work as they came from small- to medium-sized companies that had insurance for the costs of sickness absence [<xref ref-type="bibr" rid="ref54">54</xref>]</td>
                  <td>The lack of a previous existing intervention for well-being in the organization, except for the intranet, which was difficult to use, so the app resulted to be a huge advantage for employees [<xref ref-type="bibr" rid="ref36">36</xref>]</td>
                </tr>
                <tr valign="top">
                  <td>Adaptability; 4 (1.8); the degree to which an intervention can be adapted, tailored, refined, or reinvented to meet local needs</td>
                  <td>Materials presented in a modular format that had to be completed start to finish in a single sitting or in a set order [<xref ref-type="bibr" rid="ref61">61</xref>]</td>
                  <td>Possibility to use the program at their own pace [<xref ref-type="bibr" rid="ref60">60</xref>]</td>
                </tr>
                <tr valign="top">
                  <td>Design quality and packaging; 80 (36.9); perceived excellence in how the intervention is bundled, presented, and assembled</td>
                  <td>Usability was affected by unclear navigational elements and user interface [<xref ref-type="bibr" rid="ref40">40</xref>]</td>
                  <td>Improving usability based on participant and expert feedback [<xref ref-type="bibr" rid="ref40">40</xref>]</td>
                </tr>
              </tbody>
            </table>
          </table-wrap>
        </sec>
        <sec>
          <title>Outer Setting</title>
          <p>Strict external policies and failure of interventions to meet patient needs erected several barriers to the implementation of OeMH interventions (<xref ref-type="table" rid="table6">Table 6</xref>). For example, strict legislation and policies regarding privacy and confidentiality were highlighted as potential reasons for the reduced adoption of interventions based on innovative technologies [<xref ref-type="bibr" rid="ref39">39</xref>]. Moreover, failure to maintain employees’ confidentiality during these programs was believed to discourage the use of interventions for fear of being vulnerable to privacy breaches by employers [<xref ref-type="bibr" rid="ref59">59</xref>]. The sole facilitation measure identified for this CFIR domain also addresses this point by urging implementers to find ways to maintain employee confidentiality [<xref ref-type="bibr" rid="ref59">59</xref>].</p>
          <table-wrap position="float" id="table6">
            <label>Table 6</label>
            <caption>
              <p>Examples of barriers and facilitators organized under the outer setting Consolidated Framework for Implementation Research domain (N=217).</p>
            </caption>
            <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
              <col width="380"/>
              <col width="310"/>
              <col width="310"/>
              <thead>
                <tr valign="top">
                  <td>Relevant associated construct—proportion of barriers and facilitators; n (%) and brief description</td>
                  <td>Example of identified barriers</td>
                  <td>Example of identified facilitators</td>
                </tr>
              </thead>
              <tbody>
                <tr valign="top">
                  <td>External policy and incentives; 1 (0.5); a broad construct that includes external strategies to spread interventions including policy and regulations (governmental or other central entity), external mandates, recommendations and guidelines, pay for performance, collaboratives, and public or benchmark reporting</td>
                  <td>The surrounding legislation and policy regulation of privacy and confidentiality may make it difficult to use innovative technology [<xref ref-type="bibr" rid="ref39">39</xref>]</td>
                  <td>—<sup>a</sup></td>
                </tr>
                <tr valign="top">
                  <td>Patient needs and resources; 1 (0.5); the extent to which patient needs, as well as barriers and facilitators to meet those needs, are accurately known and prioritized by the organization</td>
                  <td>Reluctancy of the potential participants in participating for fear of demonstrating vulnerability [<xref ref-type="bibr" rid="ref45">45</xref>]</td>
                  <td>Maintaining confidentiality between employee and employer [<xref ref-type="bibr" rid="ref45">45</xref>]</td>
                </tr>
              </tbody>
            </table>
            <table-wrap-foot>
              <fn id="table6fn1">
                <p><sup>a</sup>No facilitator reported.</p>
              </fn>
            </table-wrap-foot>
          </table-wrap>
        </sec>
        <sec>
          <title>Inner Setting</title>
          <p>Many publications have identified the lack of resources dedicated to implementation as a major barrier (<xref ref-type="table" rid="table7">Table 7</xref>). For example, there is a lack of time for employees to use the intervention [<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref49">49</xref>,<xref ref-type="bibr" rid="ref52">52</xref>,<xref ref-type="bibr" rid="ref53">53</xref>,<xref ref-type="bibr" rid="ref59">59</xref>,<xref ref-type="bibr" rid="ref61">61</xref>], funds to meet additional costs [<xref ref-type="bibr" rid="ref39">39</xref>], unreliable systems that lead to data loss [<xref ref-type="bibr" rid="ref58">58</xref>], inflexible participation times [<xref ref-type="bibr" rid="ref42">42</xref>], lack of workspaces to avoid office distractions and private spaces [<xref ref-type="bibr" rid="ref53">53</xref>] when completing interventions [<xref ref-type="bibr" rid="ref61">61</xref>], low technology (eg, computers and email) adoption by the organization [<xref ref-type="bibr" rid="ref64">64</xref>], little support from the app or implementor [<xref ref-type="bibr" rid="ref54">54</xref>], and insufficient resources for piloting [<xref ref-type="bibr" rid="ref62">62</xref>]. Some interventions were also inadequately adjusted to organizational processes [<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref49">49</xref>,<xref ref-type="bibr" rid="ref54">54</xref>,<xref ref-type="bibr" rid="ref63">63</xref>] and insufficiently tailored to the work situation and culture [<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref54">54</xref>,<xref ref-type="bibr" rid="ref58">58</xref>,<xref ref-type="bibr" rid="ref63">63</xref>]. Organizational restructuring has also been identified as a barrier to successful implementation and should be considered during implementation planning [<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref63">63</xref>].</p>
          <p>Several facilitators have also been identified. For example, it was recommended for employers to arrange dedicated time for employees to participate in the intervention [<xref ref-type="bibr" rid="ref59">59</xref>]; to allow employees flexibility regarding the time, place, and pace when completing the intervention [<xref ref-type="bibr" rid="ref53">53</xref>]; to offer an option for employees to use the intervention in a private workspace [<xref ref-type="bibr" rid="ref53">53</xref>]; to provide recordings of any live sessions with feedback options [<xref ref-type="bibr" rid="ref42">42</xref>]; and to encourage employee access to or ownership of technology (eg, smartphone) in use [<xref ref-type="bibr" rid="ref50">50</xref>]. Intervention creators can also support employers with recruitment [<xref ref-type="bibr" rid="ref55">55</xref>], by obtaining support from a dedicated organizational support group for implementation [<xref ref-type="bibr" rid="ref58">58</xref>], providing lower-cost intervention options (eg, email based) [<xref ref-type="bibr" rid="ref58">58</xref>], using reliable data storage methods [<xref ref-type="bibr" rid="ref58">58</xref>], and demonstrating cost-effectiveness of the proposed intervention [<xref ref-type="bibr" rid="ref64">64</xref>].</p>
          <table-wrap position="float" id="table7">
            <label>Table 7</label>
            <caption>
              <p>Examples of barriers and facilitators organized under the inner setting Consolidated Framework for Implementation Research domain (N=217).</p>
            </caption>
            <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
              <col width="380"/>
              <col width="310"/>
              <col width="310"/>
              <thead>
                <tr valign="top">
                  <td>Relevant associated construct—proportion of barriers and facilitators; n (%) and brief description</td>
                  <td>Example of identified barriers</td>
                  <td>Example of identified facilitators</td>
                </tr>
              </thead>
              <tbody>
                <tr valign="top">
                  <td>Structural characteristics; 4 (1.8%); the social architecture, age, maturity, and size of an organization</td>
                  <td>Personnel shortage, turnover, and organizational restructuring hindered the use of the strategy considerably [<xref ref-type="bibr" rid="ref49">49</xref>]</td>
                  <td>Changes in the organizations should be considered (in light of resulting delays and communication problems) when planning intervention studies [<xref ref-type="bibr" rid="ref42">42</xref>]</td>
                </tr>
                <tr valign="top">
                  <td>Networks and communications; 4 (1.8%); the nature and quality of webs of social networks and the nature and quality of formal and informal communications within an organization</td>
                  <td>Restrictive internet security settings was a barrier for accessing the intervention [<xref ref-type="bibr" rid="ref42">42</xref>]</td>
                  <td>Conduct onsite testing before implementation [<xref ref-type="bibr" rid="ref42">42</xref>]</td>
                </tr>
                <tr valign="top">
                  <td>Implementation climate; 17 (7.8); the absorptive capacity for change, shared receptivity of involved individuals to an intervention, and the extent to which use of that intervention will be rewarded, supported, and expected within their organization</td>
                  <td>Alignment with other stakeholders was absent and resulted in poor adherence to the recommended roles and tasks [<xref ref-type="bibr" rid="ref62">62</xref>]</td>
                  <td>Embedding the intervention in a well-established wellness program to benefit from existing infrastructure to promote the intervention; users benefiting from incentive programs [<xref ref-type="bibr" rid="ref58">58</xref>]</td>
                </tr>
                <tr valign="top">
                  <td>Tension for change; 1 (0.5); the degree to which stakeholders perceive the current situation as intolerable or needing change</td>
                  <td>Some stakeholders may be reluctant to implement new technology as it might threaten their ability to keep their job [<xref ref-type="bibr" rid="ref39">39</xref>]</td>
                  <td>—<sup>a</sup></td>
                </tr>
                <tr valign="top">
                  <td>Compatibility; 21 (9.7); the degree of tangible fit between meaning and values attached to the intervention by involved individuals; how those align with individuals’ own norms, values, and perceived risks and needs; and how the intervention fits with existing workflows and systems</td>
                  <td>It was not possible for employees to contact their occupational physician themselves by telephone outside their regular consultations. This could have caused difficulty when an employee struggled with a module in Return@Work and wanted to ask the occupational physician for advice [<xref ref-type="bibr" rid="ref54">54</xref>]</td>
                  <td>Alignment to relevant stakeholders is also important and can be attained by offering ongoing support to leaders at all organizational levels during an implementation [<xref ref-type="bibr" rid="ref62">62</xref>]</td>
                </tr>
                <tr valign="top">
                  <td>Organizational incentives and rewards; 2 (0.9); extrinsic incentives such as goal-sharing awards, performance reviews, promotions, and raises in salary and less tangible incentives such as increased stature or respect</td>
                  <td>Complimentary gifts (eg, measuring tapes to be used by users with diabetes) with logos and information stimulate discussions and act as reminders [<xref ref-type="bibr" rid="ref64">64</xref>]</td>
                  <td>—</td>
                </tr>
                <tr valign="top">
                  <td>Readiness for implementation; 6 (2.8); tangible and immediate indicators of organizational commitment to its decision to implement an intervention</td>
                  <td>Ensuring fidelity as coaches could not provide good feedback without supervision [<xref ref-type="bibr" rid="ref63">63</xref>]</td>
                  <td>Consult review boards and consider these issues early in the data planning process [<xref ref-type="bibr" rid="ref58">58</xref>]</td>
                </tr>
                <tr valign="top">
                  <td>Leadership engagement; 7 (3.2); commitment, involvement, and accountability of leaders and managers with the implementation</td>
                  <td>Senior management was not engaged and too much responsibility for implementation was given to the team members who did not prioritize these activities [<xref ref-type="bibr" rid="ref49">49</xref>]</td>
                  <td>Adherence is better when managers are active and engaged [<xref ref-type="bibr" rid="ref64">64</xref>]</td>
                </tr>
                <tr valign="top">
                  <td>Available resources; 25 (11.5); the level of resources dedicated for implementation and ongoing operations including money, training, education, physical space, and time</td>
                  <td>The intervention required all participants to allocate the same time slot and competed with other time commitments [<xref ref-type="bibr" rid="ref42">42</xref>]</td>
                  <td>Supporting statement from the employers which will suggest to all employees who participate in the study that they will have 1 hour per week over the 8-week period to complete the program [<xref ref-type="bibr" rid="ref59">59</xref>]</td>
                </tr>
                <tr valign="top">
                  <td>Access to knowledge and information; 2 (0.9); ease of access to digestible information and knowledge about the intervention and how to incorporate it into work tasks</td>
                  <td>Email messages from the decision aid supported the occupational physicians when guiding employees. The email gave them sufficient information and the layout was visually attractive [<xref ref-type="bibr" rid="ref54">54</xref>]</td>
                  <td>
                    <break/>
                  </td>
                </tr>
              </tbody>
            </table>
            <table-wrap-foot>
              <fn id="table7fn1">
                <p><sup>a</sup>No facilitator reported.</p>
              </fn>
            </table-wrap-foot>
          </table-wrap>
        </sec>
        <sec>
          <title>Characteristics of Individuals</title>
          <p>Barriers were related to either the employer or the individual (<xref ref-type="table" rid="table8">Table 8</xref>). Employer-related barriers included the perception of low organizational commitment to addressing issues targeted by the proposed intervention [<xref ref-type="bibr" rid="ref49">49</xref>], perceived stigma associated with intervention adoption [<xref ref-type="bibr" rid="ref57">57</xref>], and a lack of privacy (eg, sharing information disclosed within the intervention with employers) [<xref ref-type="bibr" rid="ref60">60</xref>]. Individual-related barriers included a general lack of motivation and interest in using the intervention [<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref53">53</xref>], no opportunities to interact with others during the intervention [<xref ref-type="bibr" rid="ref57">57</xref>], poor consistency in using the intervention as directed [<xref ref-type="bibr" rid="ref60">60</xref>], poor digital skills [<xref ref-type="bibr" rid="ref8">8</xref>,<xref ref-type="bibr" rid="ref41">41</xref>,<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref49">49</xref>], difficulty relating to content [<xref ref-type="bibr" rid="ref60">60</xref>], low work ability [<xref ref-type="bibr" rid="ref47">47</xref>], and reduction in engagement and adoption due to symptoms associated with medical conditions [<xref ref-type="bibr" rid="ref52">52</xref>,<xref ref-type="bibr" rid="ref53">53</xref>]. Proposed facilitators include willingness to seek mental health support [<xref ref-type="bibr" rid="ref50">50</xref>], prior experience using an eHealth intervention and interventions that are freely accessible [<xref ref-type="bibr" rid="ref47">47</xref>], low technical skill requirement (eg, no authentication) [<xref ref-type="bibr" rid="ref41">41</xref>], and content that is available in multiple media formats (eg, printed versions) [<xref ref-type="bibr" rid="ref41">41</xref>,<xref ref-type="bibr" rid="ref57">57</xref>].</p>
          <table-wrap position="float" id="table8">
            <label>Table 8</label>
            <caption>
              <p>Examples of barriers and facilitators organized under the characteristics of individuals Consolidated Framework for Implementation Research domain (N=217).</p>
            </caption>
            <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
              <col width="380"/>
              <col width="310"/>
              <col width="310"/>
              <thead>
                <tr valign="top">
                  <td>Relevant associated construct—proportion of barriers and facilitators; n (%) and brief description</td>
                  <td>Example of identified barriers</td>
                  <td>Example of identified facilitators</td>
                </tr>
              </thead>
              <tbody>
                <tr valign="top">
                  <td>Knowledge and beliefs about the intervention; 7 (3.2); individuals’ attitudes toward and the value placed on the intervention as well as familiarity with facts, truths, and principles related to the intervention</td>
                  <td>Skepticism toward the independence of the project from the organization [<xref ref-type="bibr" rid="ref36">36</xref>]</td>
                  <td>Maintaining confidentiality between employee and employer [<xref ref-type="bibr" rid="ref59">59</xref>]</td>
                </tr>
                <tr valign="top">
                  <td>Self-efficacy; 12 (5.5); individual belief in their own capabilities to execute courses of action to achieve implementation goals</td>
                  <td>Lack of computer skills in team members [<xref ref-type="bibr" rid="ref49">49</xref>]</td>
                  <td>The package developed in a free-to-access and simple format that does not require logging in to a system or any specific technical expertise [<xref ref-type="bibr" rid="ref41">41</xref>]</td>
                </tr>
                <tr valign="top">
                  <td>Other personal attributes; 6 (2.8); a broad construct to include other personal traits such as tolerance of ambiguity, intellectual ability, motivation, values, competence, capacity, and learning style</td>
                  <td>Barriers reported by participants at high risk for a major depressive episode included perceived stigma, lack of interaction with others that is characteristic of eMental health, lack of time, and lack of knowledge [<xref ref-type="bibr" rid="ref57">57</xref>]</td>
                  <td>Willingness to seek professional mental health services [<xref ref-type="bibr" rid="ref50">50</xref>]</td>
                </tr>
              </tbody>
            </table>
          </table-wrap>
        </sec>
        <sec>
          <title>Summary of Facilitation Measures</title>
          <p>The identified facilitation measures were further synthesized and organized by the associated CFIR construct (<xref ref-type="table" rid="table9">Table 9</xref>).</p>
          <table-wrap position="float" id="table9">
            <label>Table 9</label>
            <caption>
              <p>Summary of potential facilitation measures organized by associated Consolidated Framework for Implementation Research (CFIR) construct.</p>
            </caption>
            <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
              <col width="260"/>
              <col width="740"/>
              <thead>
                <tr valign="top">
                  <td>Associated CFIR construct</td>
                  <td>Facilitation measure</td>
                </tr>
              </thead>
              <tbody>
                <tr valign="top">
                  <td>Evidence strength and quality</td>
                  <td>Strategies must provide evidence of effectiveness regarding the proposed or similar interventions in similar contexts featuring a representative sample of employees and a control group, where feasible, using valid and reliable measures.</td>
                </tr>
                <tr valign="top">
                  <td>Relative advantage</td>
                  <td>Strategies must be perceived to provide an advantage over the implementation of an alternative or no solution.</td>
                </tr>
                <tr valign="top">
                  <td>Adaptability</td>
                  <td>Strategies must allow flexibility on intervention completion times, the pace of progression, access options, and the format of provided materials.</td>
                </tr>
                <tr valign="top">
                  <td>Design quality and packaging</td>
                  <td>Strategies must ensure that the design of the intervention is based on an explicit understanding of users, their tasks, and environments and provides guidance (eg, reminders, knowledge base, progress tracking, and feedback); considers opportunities to integrate intervention features with organizational processes; creates personalized, informative, and nonstigmatizing content that encourages user participation; provides user adaptable content and tasks (ie, increased user control); allows access via additional modalities (eg, ability to print content) and formats (eg, video and audio); includes formative and summative usability testing and accessibility evaluations; highlights a strict approach to privacy and data security; and considers a multichannel recruitment strategy.</td>
                </tr>
                <tr valign="top">
                  <td>External policy and incentives</td>
                  <td>Strategies must identify and comply with applicable privacy legislation and policy regulations.</td>
                </tr>
                <tr valign="top">
                  <td>Structural characteristics</td>
                  <td>Strategies must consider the capacity of stakeholders to complete assigned tasks and account for turnover and other restructuring activities.</td>
                </tr>
                <tr valign="top">
                  <td>Networks and communications</td>
                  <td>Strategies must involve all stakeholders, include onsite testing of required technology, and establish clear communication procedures at the planning stage.</td>
                </tr>
                <tr valign="top">
                  <td>Implementation climate</td>
                  <td>Strategies must be cohesive and compatible with the organization’s culture (eg, high turnover and highly active working environment), ensure that interventions can be used in distraction-free environments (ie, free from excessive noise), account for prior negative experiences with similar interventions, secure support from senior management for strategy implementation, and leverage existing programs by embedding interventions into them.</td>
                </tr>
                <tr valign="top">
                  <td>Tension for change</td>
                  <td>Strategies must consider the impact of implementation on-the-job security of stakeholders and how that affects their perception of proposed changes.</td>
                </tr>
                <tr valign="top">
                  <td>Compatibility</td>
                  <td>Strategies must adequately reflect the implementation needs of the organization and its existing processes and policies; be aligned with stakeholders at different organizational levels; provide adequate separation between work and working with the intervention; and avoid stigmatization, especially of employees with mental health conditions.</td>
                </tr>
                <tr valign="top">
                  <td>Organizational incentives and rewards</td>
                  <td>Strategies should offer incentives for using the intervention and consider incorporating gamification components to offer these incentives.</td>
                </tr>
                <tr valign="top">
                  <td>Readiness for implementation</td>
                  <td>Strategies must ensure that stakeholders are involved in strategy development, aware of the strategy and their role in it, equipped with the necessary tools and access, and adequately trained to implement the strategy.</td>
                </tr>
                <tr valign="top">
                  <td>Leadership engagement</td>
                  <td>Strategies must secure support from all stakeholders, especially an active and engaged senior management who strongly sanctions and advocates for the intervention.</td>
                </tr>
                <tr valign="top">
                  <td>Available resources</td>
                  <td>Strategies must provide organizational support for implementation, intervention support for users, dedicated time and private spaces for completing interventions in the workplace, less time-intensive interventions, alternative options to live-participation activities (eg, live webinar recording), low-cost technology-based options (eg, email) for interventions, reliable cloud data storage, access from varying device types, and implementation cost estimates with demonstrated cost-effectiveness.</td>
                </tr>
                <tr valign="top">
                  <td>Access to knowledge and information</td>
                  <td>Strategies must provide information that sets realistic expectations about the intervention and how to implement it.</td>
                </tr>
                <tr valign="top">
                  <td>Knowledge and beliefs about the intervention</td>
                  <td>Strategies must clearly articulate the role of the organization in the development of the intervention and address privacy and stigmatization concerns associated with using mental health interventions.</td>
                </tr>
                <tr valign="top">
                  <td>Self-efficacy</td>
                  <td>Strategies must accommodate users whose performance is affected by symptoms (eg, lack of motivation) associated with their health conditions (eg, depression) and a lack of confidence using technology.</td>
                </tr>
                <tr valign="top">
                  <td>Individual identification with organization</td>
                  <td>Strategies must consider users’ perception of and level of commitment to the organization.</td>
                </tr>
                <tr valign="top">
                  <td>Other personal attributes</td>
                  <td>Strategies must address a lack of motivation (eg, due to symptoms associated with health conditions) to adopt and consistently use interventions and to seek help.</td>
                </tr>
              </tbody>
            </table>
          </table-wrap>
        </sec>
      </sec>
    </sec>
    <sec sec-type="discussion">
      <title>Discussion</title>
      <sec>
        <title>Principal Findings and Comparison With Prior Work</title>
        <p>The 31 included publications revealed 98 implementation strategies used when implementing OeMH interventions, 114 barriers, and 131 facilitators. The findings support observations [<xref ref-type="bibr" rid="ref12">12</xref>,<xref ref-type="bibr" rid="ref13">13</xref>] that the reporting of implementation strategies used for eHealth interventions is largely incomplete, nonsystematic, and unstructured. Nonetheless, the findings provide valuable insights into what is known and where knowledge gaps lie in the area.</p>
      </sec>
      <sec>
        <title>Implementation Strategies</title>
        <p>The OeMH knowledge base does not provide definitive answers regarding the implementation strategies to adopt and when and how it is most effective and efficient to adopt them. For example, the efficacy and cost-effectiveness of using innovative methods such as web-based targeted advertising compared with traditional methods (eg, posters) to increase reach is unclear [<xref ref-type="bibr" rid="ref66">66</xref>,<xref ref-type="bibr" rid="ref67">67</xref>], despite the former’s success in being more time-efficient [<xref ref-type="bibr" rid="ref67">67</xref>] and effective at recruiting hard-to-reach populations [<xref ref-type="bibr" rid="ref67">67</xref>,<xref ref-type="bibr" rid="ref68">68</xref>]. Those responsible for implementation must use their judgment about which of the provided strategies would be most appropriate for their circumstances. These findings support the notion that the implementation of eHealth technology (eg, eMental health [eMH] interventions) is often narrowly seen as a postdevelopment activity rather than being a crucial part of the development process [<xref ref-type="bibr" rid="ref69">69</xref>]. Nonetheless, this could be partly a consequence of many included studies not specifically or comprehensively investigating implementation and therefore not reporting other details regarding implementation. Alternatively, publication restrictions [<xref ref-type="bibr" rid="ref70">70</xref>] (eg, strict word limits) and the multidisciplinary nature of digital health research [<xref ref-type="bibr" rid="ref71">71</xref>] may prioritize other study information over details regarding implementation when reporting on digital health interventions.</p>
      </sec>
      <sec>
        <title>Barriers and Facilitators</title>
        <p>Similar to findings related to medical devices [<xref ref-type="bibr" rid="ref72">72</xref>], the findings here also suggest that usability [<xref ref-type="bibr" rid="ref73">73</xref>] appears to be the main design consideration in the evaluation of OeMH interventions, with little consideration given to other critical elements of the user experience. Findings regarding the CFIR inner setting domain highlight the need for researchers to articulate potential facilitators, including those that may have failed in one implementation context, as they might work in other contexts. Existing research [<xref ref-type="bibr" rid="ref74">74</xref>,<xref ref-type="bibr" rid="ref75">75</xref>] addresses many of the barriers (eg, associated with symptoms associated with mental health problems and limited digital literacy skills) categorized under the CFIR characteristics of individual domains and could provide an easy opportunity to improve implementation if given more consideration during the planning phase. Factors external to the organization (eg, external policies, partners, and competition) are known to greatly hinder or support the successful implementation of technology [<xref ref-type="bibr" rid="ref76">76</xref>-<xref ref-type="bibr" rid="ref78">78</xref>] but have been largely undocumented or overlooked by the included publications.</p>
      </sec>
      <sec>
        <title>Recency of Work and Coverage of Technologies</title>
        <p>Similar to recent eMH reviews focusing on college students [<xref ref-type="bibr" rid="ref79">79</xref>] and user engagement [<xref ref-type="bibr" rid="ref80">80</xref>], this review also reported an increase since 2015 in eMH intervention studies meeting broad inclusion criteria. Recent reviews [<xref ref-type="bibr" rid="ref79">79</xref>,<xref ref-type="bibr" rid="ref80">80</xref>] also found that the eMH interventions described in the included studies were primarily web-based despite the added benefits of mobile apps that are coded for a specific mobile operating system such as iOS and Android (eg, faster, functionality-rich, and offline access) [<xref ref-type="bibr" rid="ref81">81</xref>]. This is perhaps because web-based interventions likely cost less to develop and could be accessed via more devices if they were developed in a responsive way [<xref ref-type="bibr" rid="ref81">81</xref>]. Emerging technologies, including AI, were considered in our search strategy, but were not used by the OeMH interventions described in the included studies. Nonetheless, this knowledge area is expected to increasingly feature the use of emerging technologies in the near future as the focus extends beyond nascent explorations of their applications for mental health and investigates the optimization of their implementation as well [<xref ref-type="bibr" rid="ref82">82</xref>].</p>
      </sec>
      <sec>
        <title>Implications and Recommendations for Practice and Future Research</title>
        <p>Based on the findings of the scoping review, four practical recommendations could be considered to avoid and mitigate the identified barriers and improve the implementation of OeMH interventions:</p>
        <list list-type="order">
          <list-item>
            <p>Strategies must demonstrate a relative advantage over alternative solutions and promote flexibility in the delivery of interventions based on an explicit understanding of users, their tasks, and environments.</p>
          </list-item>
          <list-item>
            <p>Strategies must promote the active engagement of organizational leadership, assess organizational readiness, and ensure compatibility with the organization’s technological infrastructure and culture, in addition to providing desirable incentives and the necessary resources (eg, time and information about the intervention) for users to use the intervention as directed.</p>
          </list-item>
          <list-item>
            <p>Strategies must ensure transparency regarding the intervention and implications of use and help users build confidence in their ability to benefit from the intervention.</p>
          </list-item>
          <list-item>
            <p>Strategies must identify and ensure that interventions comply with applicable privacy legislation and policy regulations.</p>
          </list-item>
        </list>
        <p>Future IR should continue with the broad aim of understanding what, why, and how OeMH interventions work under real-world conditions, and how to improve their implementation. The findings do not support the prioritization of any one aim over others. However, findings show that IR principles [<xref ref-type="bibr" rid="ref83">83</xref>] such as the importance of context (eg, industry, size, and policies) and the people using the research need more attention for OeMH interventions. For example, surprisingly few findings were relevant to CFIR contextual domains (eg, outer setting), which speak to governmental regulations similar to COVID-19–related policies that have a strong influence on working arrangements. In addition, the general lack of detailed, systematic, and standardized reporting on proposed digital health interventions (eg, CONSORT-EHEALTH [Consolidated Standards of Reporting Trials of Electronic and Mobile Health Applications and Online Telehealth]—Expanded CONSORT figure) [<xref ref-type="bibr" rid="ref32">32</xref>,<xref ref-type="bibr" rid="ref84">84</xref>-<xref ref-type="bibr" rid="ref86">86</xref>] and the implementation strategies used to achieve these outcomes (eg, Standards for Reporting Implementation Studies) [<xref ref-type="bibr" rid="ref19">19</xref>,<xref ref-type="bibr" rid="ref70">70</xref>] need to be remedied for IR to be properly used in this area. Reporting could benefit from subscribing to technology-centric frameworks (eg, the mobile health evidence reporting and assessment checklist [<xref ref-type="bibr" rid="ref71">71</xref>] and the integrated technology implementation model [<xref ref-type="bibr" rid="ref76">76</xref>-<xref ref-type="bibr" rid="ref78">78</xref>]) that are more comprehensive in capturing key technology implementation factors (eg, accreditation, regulation, technology vendors, individual adoption factors, and interfacing systems). This should allow future studies to replicate and develop theories based on assessments of the implementation strategies used. In addition, any encountered or anticipated barriers and corresponding remedies that might be useful in avoiding these barriers or reducing their negative impact on implementation should also be reported. The development of an OeMH implementation checklist that includes comprehensive reporting guidelines and other prompts to ensure consistency and completeness when implementing these interventions would be beneficial. Future IR should also focus on investigating a wider range of common implementation outcomes (eg, cost-effectiveness and sustainability) [<xref ref-type="bibr" rid="ref87">87</xref>] facilitated by implementation strategies for OeMH interventions that also target more common mental health problems in the workplace (eg, anxiety, substance use, and addiction). Issues regarding lack of digital access and digital inequity are an ongoing challenge [<xref ref-type="bibr" rid="ref88">88</xref>], although not prominently featured in the results, and should be considered to avoid OeMH interventions contributing to any disparities. This study should also investigate how implementation strategies for OeMH interventions could benefit from emerging technologies. For instance, AI can use usage data to complement existing methods to better identify people who are at a high risk of mental health problems, support health decision-making, and offer resources that meet users’ individual health needs [<xref ref-type="bibr" rid="ref89">89</xref>]. This could have a profound positive impact on implementation through improvements in the effectiveness and maintenance of interventions.</p>
      </sec>
      <sec>
        <title>Limitations</title>
        <p>Search results were limited to publications in English, and a publication date restriction was imposed from 2010 onwards; however, given the broad search strategy, it is not anticipated that many, if any, potentially eligible publications were missed as a result. The term <italic>eMental</italic> was coined in 2002 [<xref ref-type="bibr" rid="ref90">90</xref>], merely 8 years before this review’s year restriction, and a recent review of 50 publications about OeMH interventions [<xref ref-type="bibr" rid="ref6">6</xref>] included 11 publications that were published before 2010 and none were eligible for inclusion in this study. In addition, despite our exhaustive search strategy, 6 publications from 2010 to 2015 compared with 25 from the subsequent 5-year period were eventually included. Incomplete reporting also made it challenging to detail strategies (eg, their effectiveness), barriers, facilitators, and contextual data (eg, industry, organizational size, and employee level) from the included publications and to synthesize these data later. Nonetheless, all researchers involved in data extraction completed the training specifically for this review, followed the same thorough approach, and the extracted data were reviewed at least once by a second researcher. Interrater reliability was not calculated, and reasons for disagreement in screening decisions were not reported, which might have affected the reproducibility of this study [<xref ref-type="bibr" rid="ref91">91</xref>]. However, this does not compromise the consistency and accuracy of the screening. Moreover, two 2-hour workshops were conducted with training sessions, and reconciliation meetings were consequently held when there were inconsistencies in screening decisions.</p>
        <p>Although multiple implementation strategies can legitimately contribute to multiple RE-AIM domains, adopting a framework with more specificity could potentially be useful for the identification of more targeted strategies. Common implementation models (eg, RE-AIM and CFIR) predate the current development of eHealth, and concerns about their inability to fully capture the complexities of eHealth implementation have been raised [<xref ref-type="bibr" rid="ref69">69</xref>] and persist [<xref ref-type="bibr" rid="ref92">92</xref>] despite some recent updates [<xref ref-type="bibr" rid="ref32">32</xref>,<xref ref-type="bibr" rid="ref86">86</xref>] and clarifications [<xref ref-type="bibr" rid="ref33">33</xref>]. Nonetheless, these generic frameworks are useful for guiding data extraction and as tools for making valuable comparisons with other types of interventions. Similar to other scoping reviews, this review reports on the nature and features of the literature on the topic of focus and does not attempt to present a view regarding the appropriateness of the used methods and the strength or quality of evidence. Similarly, the provision of more detailed recommendations would have been premature and potentially misleading, as this was unsupported by the data collected. Further research is needed to determine valid facilitators and how they should be used in the process of OeMH development and delivery on a case-by-case basis while considering contextual factors such as industry, organizational size, employee level, and internal and external policies. Nevertheless, these recommendations could still be particularly relevant for OeMH interventions in comparison with similar interventions in different contexts. Consequently, readers should be mindful that the review cannot determine whether the included studies provide robust or generalizable findings.</p>
      </sec>
      <sec>
        <title>Conclusions</title>
        <p>This scoping review represents one of the first steps in a research agenda aimed at improving the implementation of OeMH interventions by systematically selecting, shaping, evaluating, and reporting implementation strategies. It has identified 98 implementation strategies, 114 barriers, and 131 facilitation measures related to the implementation of these interventions. A synthesis of these findings offers 19 recommendations that provide initial guidance on how to improve the implementation of OeMH interventions. This scoping review also highlighted the need to combine common implementation models (eg, RE-AIM and CFIR) with more technology-centric frameworks (eg, integrated technology implementation model and the mobile health evidence reporting and assessment checklist) to fully capture the complexities of eHealth implementation. Despite yielding less detailed insight than hoped, owing to incomplete reporting and the adoption of incomprehensive frameworks by the included publications, this scoping review’s findings can still be critically leveraged by discerning decision-makers to improve the reach, effectiveness, adoption, implementation, and maintenance of OeMH interventions.</p>
      </sec>
    </sec>
  </body>
  <back>
    <app-group>
      <supplementary-material id="app1">
        <label>Multimedia Appendix 1</label>
        <p>Search concepts and terms and MEDLINE search strategy.</p>
        <media xlink:href="jmir_v24i6e34479_app1.docx" xlink:title="DOCX File , 16 KB"/>
      </supplementary-material>
      <supplementary-material id="app2">
        <label>Multimedia Appendix 2</label>
        <p>Identified examples of implementation strategies organized by relevant reach, effectiveness, adoption, implementation, and maintenance domains.</p>
        <media xlink:href="jmir_v24i6e34479_app2.xlsx" xlink:title="XLSX File  (Microsoft Excel File), 18 KB"/>
      </supplementary-material>
      <supplementary-material id="app3">
        <label>Multimedia Appendix 3</label>
        <p>Identified barriers and facilitators organized by relevant Consolidated Framework for Implementation Research domain and associated construct.</p>
        <media xlink:href="jmir_v24i6e34479_app3.xlsx" xlink:title="XLSX File  (Microsoft Excel File), 25 KB"/>
      </supplementary-material>
    </app-group>
    <glossary>
      <title>Abbreviations</title>
      <def-list>
        <def-item>
          <term id="abb1">AI</term>
          <def>
            <p>artificial intelligence</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb2">CFIR</term>
          <def>
            <p>Consolidated Framework for Implementation Research</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb3">CONSORT-EHEALTH</term>
          <def>
            <p>Consolidated Standards of Reporting Trials of Electronic and Mobile Health Applications and Online Telehealth</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb4">eMH</term>
          <def>
            <p>eMental health</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb5">EMPOWER</term>
          <def>
            <p>European Platform to Promote Well-being and Health in the Workplace</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb6">IR</term>
          <def>
            <p>implementation research</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb7">OeMH</term>
          <def>
            <p>Occupational eMental health</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb8">PRISMA-ScR</term>
          <def>
            <p>Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb9">RE-AIM</term>
          <def>
            <p>reach, effectiveness, adoption, implementation, and maintenance</p>
          </def>
        </def-item>
      </def-list>
    </glossary>
    <ack>
      <p>The research leading to these results received funding from the European Union Horizon 2020 Research and Innovation Programme under grant 848180 and the National Health and Medical Research Council of Australia under grant APP1195937. CdM received funding in the form of a predoctoral grant from Generalitat de Catalunya (PIF-Salut grant, code SLT017/20/000138).</p>
      <p>The authors especially thank Dr Beatriz Olaya, Dr Christophe Vanroelen, Ellen Vorstenbosch, Dr Desirée Gutiérrez Marín, and other colleagues from the European Platform to Promote Well-being and Health in the Workplace Consortium for their generous feedback on the manuscript.</p>
    </ack>
    <fn-group>
      <fn fn-type="conflict">
        <p>None declared.</p>
      </fn>
    </fn-group>
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