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<article article-type="letter" dtd-version="2.0" xmlns:xlink="http://www.w3.org/1999/xlink">
  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JMIR</journal-id>
      <journal-id journal-id-type="nlm-ta">J Med Internet Res</journal-id>
      <journal-title>Journal of Medical Internet Research</journal-title>
      <issn pub-type="epub">1438-8871</issn>
      <publisher>
        <publisher-name>JMIR Publications</publisher-name>
        <publisher-loc>Toronto, Canada</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">v24i3e36739</article-id>
      <article-id pub-id-type="pmid">35275073</article-id>
      <article-id pub-id-type="doi">10.2196/36739</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Letter to the Editor</subject>
        </subj-group>
        <subj-group subj-group-type="article-type">
          <subject>Letter to the Editor</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Toward a Better Understanding of Quality Social Connections. Comment on “Quality Social Connection as an Active Ingredient in Digital Interventions for Young People With Depression and Anxiety: Systematic Scoping Review and Meta-analysis”</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="editor">
          <name>
            <surname>Leung</surname>
            <given-names>Tiffany</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib id="contrib1" contrib-type="author">
          <name name-style="western">
            <surname>Deng</surname>
            <given-names>Huachu</given-names>
          </name>
          <degrees>MD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-4501-7186</ext-link>
        </contrib>
        <contrib id="contrib2" contrib-type="author" corresp="yes">
          <name name-style="western">
            <surname>Qin</surname>
            <given-names>Xingan</given-names>
          </name>
          <degrees>MD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <address>
            <institution>Department of Gastrointestinal and Gland Surgery</institution>
            <institution>First Affiliated Hospital of Guangxi Medical University</institution>
            <addr-line>6 Shuangyong Road</addr-line>
            <addr-line>Qingxiu District</addr-line>
            <addr-line>Nanning, 530000</addr-line>
            <country>China</country>
            <phone>86 15277114948</phone>
            <email>drqinxingan@126.com</email>
          </address>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0003-0028-0471</ext-link>
        </contrib>
      </contrib-group>
      <aff id="aff1">
        <label>1</label>
        <institution>Department of Gastrointestinal and Gland Surgery</institution>
        <institution>First Affiliated Hospital of Guangxi Medical University</institution>
        <addr-line>Nanning</addr-line>
        <country>China</country>
      </aff>
      <author-notes>
        <corresp>Corresponding Author: Xingan Qin <email>drqinxingan@126.com</email></corresp>
      </author-notes>
      <pub-date pub-type="collection">
        <month>3</month>
        <year>2022</year>
      </pub-date>
      <pub-date pub-type="epub">
        <day>11</day>
        <month>3</month>
        <year>2022</year>
      </pub-date>
      <volume>24</volume>
      <issue>3</issue>
      <elocation-id>e36739</elocation-id>
      <history>
        <date date-type="received">
          <day>23</day>
          <month>1</month>
          <year>2022</year>
        </date>
        <date date-type="accepted">
          <day>24</day>
          <month>1</month>
          <year>2022</year>
        </date>
      </history>
      <copyright-statement>©Huachu Deng, Xingan Qin. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 11.03.2022.</copyright-statement>
      <copyright-year>2022</copyright-year>
      <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
        <p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Journal of Medical Internet Research, is properly cited. The complete bibliographic information, a link to the original publication on https://www.jmir.org/, as well as this copyright and license information must be included.</p>
      </license>
      <self-uri xlink:href="https://www.jmir.org/2022/3/e36739" xlink:type="simple"/>
      <related-article related-article-type="commentary-article" id="v23i12e26584" ext-link-type="doi" xlink:href="10.2196/26584" vol="23" page="e26584" xlink:type="simple">https://www.jmir.org/2021/12/e26584</related-article>
      <related-article related-article-type="commentary" id="v24i3e37440" ext-link-type="doi" xlink:href="10.2196/mhealth.7413" vol="24" page="e37440" xlink:type="simple">https://www.jmir.org/2022/3/e37440</related-article>
      <kwd-group>
        <kwd>mental health</kwd>
        <kwd>digital interventions</kwd>
        <kwd>young people</kwd>
        <kwd>quality social connection</kwd>
        <kwd>depression</kwd>
        <kwd>anxiety</kwd>
        <kwd>systematic review</kwd>
        <kwd>meta-analysis</kwd>
        <kwd>patient and public involvement</kwd>
        <kwd>mobile phone</kwd>
      </kwd-group>
      <abstract>
        <p> </p>
      </abstract>
    </article-meta>
  </front>
  <body>
    <p>We read the paper by Dewa et al [<xref ref-type="bibr" rid="ref1">1</xref>] with interest. The authors performed a meta-analysis to conceptualize, appraise, and synthesize evidence on quality social connection (QSC) within digital interventions (D-QSC) and the impact on depression and anxiety outcomes for young people aged 14-24 years. They demonstrated that “D-QSC is an important and underconsidered component for youth depression and anxiety outcomes. Researchers and developers should consider targeting improved QSC between clinicians and young people within digital interventions for depression. Future research should build on our framework to further examine relationships among individual attributes of QSC, various digital interventions, and different populations.” After carefully reading, I wish to put forth the following suggestions.</p>
    <p>Two studies [<xref ref-type="bibr" rid="ref2">2</xref>,<xref ref-type="bibr" rid="ref3">3</xref>] in Table 2 (“Data extraction and quality assessment of included studies”) were created by the same author team (Radovic et al) with similar characteristics (year, country, study design, setting and participants, digital intervention, and outcomes and measures). This duplicate inclusion of data would affect the credibility of the final results of the meta-analysis. I recommend that the authors exclude duplicate works in the meta-analysis and that a correction and reliable checking of the data insertion is required.</p>
    <p>Due to these mistakes, I suggest that the authors further refine the inclusion criteria for the included studies to avoid duplication of inclusion.</p>
  </body>
  <back>
    <app-group/>
    <glossary>
      <title>Abbreviations</title>
      <def-list>
        <def-item>
          <term id="abb1">D-QSC</term>
          <def>
            <p>quality social connection within digital interventions</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb2">QSC</term>
          <def>
            <p>quality social connection</p>
          </def>
        </def-item>
      </def-list>
    </glossary>
    <ack>
      <p>We are supported by the Department of Gastrointestinal and Gland Surgery at the First Affiliated Hospital of Guangxi Medical University.</p>
    </ack>
    <fn-group>
      <fn fn-type="conflict">
        <p>None declared.</p>
      </fn>
    </fn-group>
    <ref-list>
      <ref id="ref1">
        <label>1</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Dewa</surname>
              <given-names>LH</given-names>
            </name>
            <name name-style="western">
              <surname>Lawrance</surname>
              <given-names>E</given-names>
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  </back>
</article>
