<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD Journal Publishing DTD v2.0 20040830//EN" "http://dtd.nlm.nih.gov/publishing/2.0/journalpublishing.dtd">
<article article-type="letter" dtd-version="2.0" xmlns:xlink="http://www.w3.org/1999/xlink">
  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JMIR</journal-id>
      <journal-id journal-id-type="nlm-ta">J Med Internet Res</journal-id>
      <journal-title>Journal of Medical Internet Research</journal-title>
      <issn pub-type="epub">1438-8871</issn>
      <publisher>
        <publisher-name>JMIR Publications</publisher-name>
        <publisher-loc>Toronto, Canada</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">v24i10e40876</article-id>
      <article-id pub-id-type="pmid">36256826</article-id>
      <article-id pub-id-type="doi">10.2196/40876</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Research Letter</subject>
        </subj-group>
        <subj-group subj-group-type="article-type">
          <subject>Research Letter</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>An Increase in Antibiotic Prescribing for Respiratory Tract Infections Through Telehealth Consultations: Retrospective Study in Australian General Practice</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="editor">
          <name>
            <surname>Leung</surname>
            <given-names>Tiffany</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Tramper-Stranders</surname>
            <given-names>Gerdien</given-names>
          </name>
        </contrib>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Leitch</surname>
            <given-names>Sharon</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib id="contrib1" contrib-type="author" corresp="yes" equal-contrib="yes">
          <name name-style="western">
            <surname>Imai</surname>
            <given-names>Chisato</given-names>
          </name>
          <degrees>BSc, MPH, PhD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <address>
            <institution>Australian Institute of Health Innovation</institution>
            <institution>Macquarie University</institution>
            <addr-line>​75 ​Talavera Road</addr-line>
            <addr-line>Level 6</addr-line>
            <addr-line>Sydney, 2109</addr-line>
            <country>Australia</country>
            <phone>61 02 9850 2415</phone>
            <email>chrissy.imai@mq.edu.au</email>
          </address>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-0080-1487</ext-link>
        </contrib>
        <contrib id="contrib2" contrib-type="author" equal-contrib="yes">
          <name name-style="western">
            <surname>Amin</surname>
            <given-names>Janaki</given-names>
          </name>
          <degrees>BSc, MPH, PhD</degrees>
          <xref rid="aff2" ref-type="aff">2</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0003-2161-9366</ext-link>
        </contrib>
        <contrib id="contrib3" contrib-type="author" equal-contrib="yes">
          <name name-style="western">
            <surname>Prgomet</surname>
            <given-names>Mirela</given-names>
          </name>
          <degrees>PhD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0001-5629-3680</ext-link>
        </contrib>
        <contrib id="contrib4" contrib-type="author" equal-contrib="yes">
          <name name-style="western">
            <surname>Pearce</surname>
            <given-names>Christopher</given-names>
          </name>
          <degrees>MBBS, MFA, PhD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <xref rid="aff3" ref-type="aff">3</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-3132-6033</ext-link>
        </contrib>
        <contrib id="contrib5" contrib-type="author" equal-contrib="yes">
          <name name-style="western">
            <surname>Georgiou</surname>
            <given-names>Andrew</given-names>
          </name>
          <degrees>BSc, PhD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-7619-3668</ext-link>
        </contrib>
      </contrib-group>
      <aff id="aff1">
        <label>1</label>
        <institution>Australian Institute of Health Innovation</institution>
        <institution>Macquarie University</institution>
        <addr-line>Sydney</addr-line>
        <country>Australia</country>
      </aff>
      <aff id="aff2">
        <label>2</label>
        <institution>Department of Health Sciences</institution>
        <institution>Macquarie University</institution>
        <addr-line>Sydney</addr-line>
        <country>Australia</country>
      </aff>
      <aff id="aff3">
        <label>3</label>
        <institution>Aurora Primary Care Research Institute</institution>
        <addr-line>Blackburn</addr-line>
        <country>Australia</country>
      </aff>
      <author-notes>
        <corresp>Corresponding Author: Chisato Imai <email>chrissy.imai@mq.edu.au</email></corresp>
      </author-notes>
      <pub-date pub-type="collection">
        <month>10</month>
        <year>2022</year>
      </pub-date>
      <pub-date pub-type="epub">
        <day>18</day>
        <month>10</month>
        <year>2022</year>
      </pub-date>
      <volume>24</volume>
      <issue>10</issue>
      <elocation-id>e40876</elocation-id>
      <history>
        <date date-type="received">
          <day>8</day>
          <month>7</month>
          <year>2022</year>
        </date>
        <date date-type="rev-request">
          <day>31</day>
          <month>8</month>
          <year>2022</year>
        </date>
        <date date-type="rev-recd">
          <day>14</day>
          <month>9</month>
          <year>2022</year>
        </date>
        <date date-type="accepted">
          <day>21</day>
          <month>9</month>
          <year>2022</year>
        </date>
      </history>
      <copyright-statement>©Chisato Imai, Janaki Amin, Mirela Prgomet, Christopher Pearce, Andrew Georgiou. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 18.10.2022.</copyright-statement>
      <copyright-year>2022</copyright-year>
      <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
        <p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Journal of Medical Internet Research, is properly cited. The complete bibliographic information, a link to the original publication on https://www.jmir.org/, as well as this copyright and license information must be included.</p>
      </license>
      <self-uri xlink:href="https://www.jmir.org/2022/10/e40876" xlink:type="simple"/>
      <kwd-group>
        <kwd>general practice</kwd>
        <kwd>anti-infective agents</kwd>
        <kwd>antibiotics</kwd>
        <kwd>medication</kwd>
        <kwd>prescriptions</kwd>
        <kwd>respiratory tract infections</kwd>
        <kwd>infection</kwd>
        <kwd>telehealth</kwd>
        <kwd>telemedicine</kwd>
        <kwd>Australia</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec sec-type="introduction">
      <title>Introduction</title>
      <p>General practitioners (GPs) are the first point of contact for most people in Australia seeking medical attention. They play an important role in the prevention, early detection, and management of both acute and chronic diseases. In Australian general practice, antibiotics are commonly prescribed for respiratory tract infections (RTIs) despite evidence of limited efficacy [<xref ref-type="bibr" rid="ref1">1</xref>,<xref ref-type="bibr" rid="ref2">2</xref>]. A previous study identified that the antibiotic prescribing rates for RTIs by GPs are up to 9 times higher than recommended by practice guidelines [<xref ref-type="bibr" rid="ref3">3</xref>]. Such findings have raised public health concerns about overprescribing antibiotics, emphasizing the need for continued monitoring of antibiotic prescribing activities in Australian general practice.</p>
      <p>In mid-March 2020, the Australian government implemented the expansion of telehealth services covered by Medicare (Australia’s universal health insurance) in response to the COVID-19 pandemic. Subsequently, many GPs shifted care delivery from face-to-face consultations to telehealth (telephone or video-conference consultations). A study conducted in the early stage of the pandemic showed lower rates of medication prescriptions via telehealth compared to face-to-face consultations in Australian general practice [<xref ref-type="bibr" rid="ref4">4</xref>]; however, antibiotic prescribing for RTIs by consultation modality is yet to be explored. Therefore, we examined antibiotic prescribing for RTIs via telehealth in comparison with face-to-face consultations from April 2020 to November 2021.</p>
    </sec>
    <sec sec-type="methods">
      <title>Methods</title>
      <sec>
        <title>Data and Analysis</title>
        <p>This retrospective study used data from the Population Level Analysis and Reporting (POLAR) platform [<xref ref-type="bibr" rid="ref4">4</xref>]. POLAR comprises deidentified electronic health records collated from approximately 1000 general practices across 2 states in Australia (ie, Victoria and New South Wales). To obtain our variables of interest, diagnosis data were used to identify consultations for respiratory infections based on SNOMED-CT (Systematized Nomenclature of Medicine – Clinical Terms) codes (respiratory infection, [viral/bacterial/recurrent/acute] upper respiratory tract infection, and [viral/bacterial/recurrent/acute] lower respiratory tract infection); antibiotic prescriptions were identified via the Anatomical Therapeutic Chemical code J01 (antibacterials for systemic use) in prescription data; and consultation modality was defined based on service item numbers from Medicare billing data [<xref ref-type="bibr" rid="ref5">5</xref>].</p>
        <p>For the analysis, we examined the mean weekly percentage of consultations with antibiotic prescribing between April 1, 2020, and November 30, 2021. We also determined the patient-level probability of an antibiotic being prescribed during consultations in the periods June to November 2020 and June to November 2021, using generalized estimating equations with the Huber-White standard error, adjusted for patient factors (age, gender, remoteness, state of residence, active status as defined by the Royal Australian College of General Practitioners [RACGP], and recent history of consultation) and a sampling effect within the general practices. Active patients (ie, regular visitors to a practice) were defined based on the definition from the RACGP as individuals who had attended the practices 3 or more times in the past 2 years at the time of visit [<xref ref-type="bibr" rid="ref6">6</xref>].</p>
      </sec>
      <sec>
        <title>Ethics Approval</title>
        <p>Ethics approval was obtained from the Macquarie University Human Research Ethics Committee (#52020675617176).</p>
      </sec>
    </sec>
    <sec sec-type="results">
      <title>Results</title>
      <p>Between April 2020 and November 2021, a total of 105,719 individuals had an RTI diagnosis and attended 141,444 consultations: 92,318 (65.3%) face-to-face visits and 49,126 (34.7%) telehealth consultations (comprising 48,159 via telephone and 967 via video conference).</p>
      <p>In 2020, the weekly mean antibiotic prescribing rates for RTIs were 56.7% (95% CI 54.2%-59.3%) for face-to-face consultations and 40.8% (95% CI 37.2%-44.4%) for telehealth (<xref rid="figure1" ref-type="fig">Figure 1</xref>). In 2021, the weekly mean prescribing rates were 58.6% (95% CI 55.8%-61.4%) for face to face and 61.0% (95% CI 59.1%-63.0%) for telehealth. We also evaluated the number of prescriptions during the study period and observed the same longitudinal trend.</p>
      <p>At the patient level, the probability of receiving an antibiotic prescription through a telehealth consultation also increased from 59.3% (95% CI 57.6%-61.0%) in 2020 to 65.7% (95% CI 64.4%-67.0%) in 2021 (<xref ref-type="table" rid="table1">Table 1</xref>). The probability via face-to-face consultations was consistent across 2020 and 2021: 65.2% (95% CI 63.4%-66.9%) and 66.9% (95% CI 65.5%-68.2%), respectively.</p>
      <fig id="figure1" position="float">
        <label>Figure 1</label>
        <caption>
          <p>Weekly mean percentage of respiratory tract infection consultations with an antibiotic prescription for F2F and telehealth consultations (April 2020 to November 2021). F2F: face-to-face; NSW: New South Wales; VIC: Victoria.</p>
        </caption>
        <graphic xlink:href="jmir_v24i10e40876_fig1.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
      </fig>
      <table-wrap position="float" id="table1">
        <label>Table 1</label>
        <caption>
          <p>Patient probability of receiving antibiotic prescriptions in a consultation for respiratory tract infection.</p>
        </caption>
        <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
          <col width="30"/>
          <col width="270"/>
          <col width="220"/>
          <col width="480"/>
          <thead>
            <tr valign="top">
              <td colspan="2">Variables</td>
              <td colspan="2">Estimated probability (%) of receiving antibiotic prescription (95% CI)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>2020</td>
              <td>2021</td>
            </tr>
          </thead>
          <tbody>
            <tr valign="top">
              <td colspan="4">
                <bold>Age group (years)</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>&lt;10</td>
              <td>54.2 (52.0-56.6)</td>
              <td>54.7 (53.0-56.4)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>10-24</td>
              <td>50.5 (47.6-53.6)</td>
              <td>59.1 (56.3-62.0)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>25-44</td>
              <td>61.6 (58.9-64.5)</td>
              <td>67.7 (65.9-69.6)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>45-64</td>
              <td>74.6 (71.2-78.1)</td>
              <td>73.2 (71.0-75.5)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>≥65</td>
              <td>93.4 (87.7-99.4)</td>
              <td>83.3 (80.3-86.5)</td>
            </tr>
            <tr valign="top">
              <td colspan="4">
                <bold>Sex</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Female</td>
              <td>65.2 (63.4-66.9)</td>
              <td>66.9 (65.5-68.2)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Male</td>
              <td>58.0 (56.2-59.8)</td>
              <td>65.6 (64.1-67.1)</td>
            </tr>
            <tr valign="top">
              <td colspan="4">
                <bold>Active status</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Nonactive</td>
              <td>48.9 (47.2-50.7)</td>
              <td>51.9 (50.3-53.6)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Active</td>
              <td>65.2 (63.4-66.9)</td>
              <td>66.9 (65.5-68.2)</td>
            </tr>
            <tr valign="top">
              <td colspan="4">
                <bold>Remoteness</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Major cities</td>
              <td>65.2 (63.4-66.9)</td>
              <td>66.9 (65.5-68.2)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Regional or remote areas</td>
              <td>75.8 (72.1-79.7)</td>
              <td>77.3 (74.9-79.7)</td>
            </tr>
            <tr valign="top">
              <td colspan="4">
                <bold>Previous encounter (≤2 weeks)</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>No</td>
              <td>65.2 (63.4-66.9)</td>
              <td>66.9 (65.5-68.2)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Yes</td>
              <td>63.6 (61.9-65.3)</td>
              <td>66.5 (65.2-67.9)</td>
            </tr>
            <tr valign="top">
              <td colspan="4">
                <bold>State</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>New South Wales</td>
              <td>65.2 (63.4-66.9)</td>
              <td>67.7 (66.4-69.1)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Victoria</td>
              <td>54.6 (52.9-56.4)</td>
              <td>66.9 (65.5-68.2)</td>
            </tr>
            <tr valign="top">
              <td colspan="4">
                <bold>Consultation</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Face to face</td>
              <td>65.2 (63.4-66.9)</td>
              <td>66.9 (65.5-68.2)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Telehealth</td>
              <td>59.3 (57.6-61.0)</td>
              <td>65.7 (64.4-67.0)</td>
            </tr>
          </tbody>
        </table>
      </table-wrap>
    </sec>
    <sec sec-type="discussion">
      <title>Discussion</title>
      <p>Antibiotic prescribing via telehealth increased over time, with rates initially much lower than face-to-face consultations; however, the prescribing rates between the two consultation modalities became equivalent toward the end of 2021.</p>
      <p>While telehealth offers some advantages such as less travel time and prevention of infectious disease transmissions, the caveats include limited physical examination capabilities. Such limitations may potentially impact the adequacy of medication prescribing, particularly in populations like children who have difficulty verbalizing symptoms.</p>
      <p>Considering that high antibiotic prescribing rates for RTIs by Australian GPs is a long-standing public health concern, the findings from this study highlight the need for monitoring the impacts of telehealth on medication prescribing in general practice. Further, studies on telehealth decision-making processes for antibiotic prescribing that evaluate prescribing adequacy appear critical.</p>
    </sec>
  </body>
  <back>
    <app-group/>
    <glossary>
      <title>Abbreviations</title>
      <def-list>
        <def-item>
          <term id="abb1">GP</term>
          <def>
            <p>general practitioner</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb2">POLAR</term>
          <def>
            <p>Population Level Analysis and Reporting</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb3">RTI</term>
          <def>
            <p>respiratory tract infection</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb4">RACGP</term>
          <def>
            <p>Royal Australian College of General Practitioners</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb5">SNOMED-CT</term>
          <def>
            <p>Systematized Nomenclature of Medicine – Clinical Terms</p>
          </def>
        </def-item>
      </def-list>
    </glossary>
    <ack>
      <p>We would like to thank and acknowledge all general practitioners, participating Primary Health Networks, as well as the data custodian Outcome Health. This research was also supported by Digital Health CRC Limited, which is funded under the Commonwealth’s Cooperative Research Centres Program.</p>
    </ack>
    <fn-group>
      <fn fn-type="conflict">
        <p>None declared.</p>
      </fn>
    </fn-group>
    <ref-list>
      <ref id="ref1">
        <label>1</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Del Mar</surname>
              <given-names>CB</given-names>
            </name>
            <name name-style="western">
              <surname>Scott</surname>
              <given-names>AM</given-names>
            </name>
            <name name-style="western">
              <surname>Glasziou</surname>
              <given-names>PP</given-names>
            </name>
            <name name-style="western">
              <surname>Hoffmann</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>van Driel</surname>
              <given-names>ML</given-names>
            </name>
            <name name-style="western">
              <surname>Beller</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Phillips</surname>
              <given-names>SM</given-names>
            </name>
            <name name-style="western">
              <surname>Dartnell</surname>
              <given-names>J</given-names>
            </name>
          </person-group>
          <article-title>Reducing antibiotic prescribing in Australian general practice: time for a national strategy</article-title>
          <source>Med J Aust</source>
          <year>2017</year>
          <month>11</month>
          <day>6</day>
          <volume>207</volume>
          <issue>9</issue>
          <fpage>401</fpage>
          <lpage>406</lpage>
          <pub-id pub-id-type="doi">10.5694/mja17.00574</pub-id>
          <pub-id pub-id-type="medline">29092694</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref2">
        <label>2</label>
        <nlm-citation citation-type="web">
          <article-title>AURA 2016: first Australian report on antimicrobial use and resistance in human health</article-title>
          <source>Australian Commission on Safety and Quality in Health Care</source>
          <year>2016</year>
          <access-date>2022-03-30</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.safetyandquality.gov.au/publications-and-resources/resource-library/aura-2016-first-australian-report-antimicrobial-use-and-resistance-human-health-full-report">https://www.safetyandquality.gov.au/publications-and-resources/resource-library/aura-2016-first-australian-report-antimicrobial-use-and-resistance-human-health-full-report</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref3">
        <label>3</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>McCullough</surname>
              <given-names>Amanda R</given-names>
            </name>
            <name name-style="western">
              <surname>Pollack</surname>
              <given-names>Allan J</given-names>
            </name>
            <name name-style="western">
              <surname>Plejdrup Hansen</surname>
              <given-names>Malene</given-names>
            </name>
            <name name-style="western">
              <surname>Glasziou</surname>
              <given-names>Paul P</given-names>
            </name>
            <name name-style="western">
              <surname>Looke</surname>
              <given-names>David Fm</given-names>
            </name>
            <name name-style="western">
              <surname>Britt</surname>
              <given-names>Helena C</given-names>
            </name>
            <name name-style="western">
              <surname>Del Mar</surname>
              <given-names>Christopher B</given-names>
            </name>
          </person-group>
          <article-title>Antibiotics for acute respiratory infections in general practice: comparison of prescribing rates with guideline recommendations</article-title>
          <source>Med J Aust</source>
          <year>2017</year>
          <month>07</month>
          <day>17</day>
          <volume>207</volume>
          <issue>2</issue>
          <fpage>65</fpage>
          <lpage>69</lpage>
          <pub-id pub-id-type="doi">10.5694/mja16.01042</pub-id>
          <pub-id pub-id-type="medline">28701117</pub-id>
          <pub-id pub-id-type="pii">10.5694/mja16.01042</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref4">
        <label>4</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Wabe</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Thomas</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Sezgin</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Sheikh</surname>
              <given-names>Muhammad Kashif</given-names>
            </name>
            <name name-style="western">
              <surname>Gault</surname>
              <given-names>Emma</given-names>
            </name>
            <name name-style="western">
              <surname>Georgiou</surname>
              <given-names>Andrew</given-names>
            </name>
          </person-group>
          <article-title>Medication prescribing in face-to-face versus telehealth consultations during the COVID-19 pandemic in Australian general practice: a retrospective observational study</article-title>
          <source>BJGP Open</source>
          <year>2022</year>
          <month>03</month>
          <volume>6</volume>
          <issue>1</issue>
          <fpage>6</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="http://bjgpopen.org/cgi/pmidlookup?view=long&amp;pmid=34819296"/>
          </comment>
          <pub-id pub-id-type="doi">10.3399/BJGPO.2021.0132</pub-id>
          <pub-id pub-id-type="medline">34819296</pub-id>
          <pub-id pub-id-type="pii">BJGPO.2021.0132</pub-id>
          <pub-id pub-id-type="pmcid">PMC8958736</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref5">
        <label>5</label>
        <nlm-citation citation-type="web">
          <article-title>COVID-19 telehealth MBS items</article-title>
          <source>Department of Health and Aged Care, Australian Government</source>
          <year>2020</year>
          <month>08</month>
          <day>13</day>
          <access-date>2022-09-07</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="http://www.mbsonline.gov.au/internet/mbsonline/publishing.nsf/Content/news-2020-03-29-latest-news-March">http://www.mbsonline.gov.au/internet/mbsonline/publishing.nsf/Content/news-2020-03-29-latest-news-March</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref6">
        <label>6</label>
        <nlm-citation citation-type="web">
          <article-title>Standards for general practices, 4th edition</article-title>
          <source>The Royal Australian College of General Practitioners</source>
          <access-date>2022-03-30</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.racgp.org.au/running-a-practice/practice-standards/standards-4th-edition">https://www.racgp.org.au/running-a-practice/practice-standards/standards-4th-edition</ext-link>
          </comment>
        </nlm-citation>
      </ref>
    </ref-list>
  </back>
</article>
