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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JMIR</journal-id>
      <journal-id journal-id-type="nlm-ta">J Med Internet Res</journal-id>
      <journal-title>Journal of Medical Internet Research</journal-title>
      <issn pub-type="epub">1438-8871</issn>
      <publisher>
        <publisher-name>JMIR Publications</publisher-name>
        <publisher-loc>Toronto, Canada</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">v24i10e36134</article-id>
      <article-id pub-id-type="pmid">36315229</article-id>
      <article-id pub-id-type="doi">10.2196/36134</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Review</subject>
        </subj-group>
        <subj-group subj-group-type="article-type">
          <subject>Review</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Interventions Including Smart Technology Compared With Face-to-face Physical Activity Interventions in Older Adults: Systematic Review and Meta-analysis</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="editor">
          <name>
            <surname>Eysenbach</surname>
            <given-names>Gunther</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Videira-Silva</surname>
            <given-names>António</given-names>
          </name>
        </contrib>
        <contrib contrib-type="reviewer">
          <name>
            <surname>De La Torre</surname>
            <given-names>Steven</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib id="contrib1" contrib-type="author" equal-contrib="yes">
          <name name-style="western">
            <surname>D'Amore</surname>
            <given-names>Cassandra</given-names>
          </name>
          <degrees>BSc (Hons)</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0001-5374-444X</ext-link>
        </contrib>
        <contrib id="contrib2" contrib-type="author" equal-contrib="yes">
          <name name-style="western">
            <surname>Reid</surname>
            <given-names>Julie C</given-names>
          </name>
          <degrees>PT, PhD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-1424-3105</ext-link>
        </contrib>
        <contrib id="contrib3" contrib-type="author">
          <name name-style="western">
            <surname>Chan</surname>
            <given-names>Matthew</given-names>
          </name>
          <degrees>MScPT</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0001-6234-2223</ext-link>
        </contrib>
        <contrib id="contrib4" contrib-type="author">
          <name name-style="western">
            <surname>Fan</surname>
            <given-names>Samuel</given-names>
          </name>
          <degrees>MScPT</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0001-8368-1857</ext-link>
        </contrib>
        <contrib id="contrib5" contrib-type="author">
          <name name-style="western">
            <surname>Huang</surname>
            <given-names>Amanda</given-names>
          </name>
          <degrees>MScPT</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-4278-4881</ext-link>
        </contrib>
        <contrib id="contrib6" contrib-type="author">
          <name name-style="western">
            <surname>Louie</surname>
            <given-names>Jonathan</given-names>
          </name>
          <degrees>MScPT</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-3315-831X</ext-link>
        </contrib>
        <contrib id="contrib7" contrib-type="author">
          <name name-style="western">
            <surname>Tran</surname>
            <given-names>Andy</given-names>
          </name>
          <degrees>MScPT</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0003-0470-2811</ext-link>
        </contrib>
        <contrib id="contrib8" contrib-type="author">
          <name name-style="western">
            <surname>Chauvin</surname>
            <given-names>Stephanie</given-names>
          </name>
          <degrees>MSc</degrees>
          <xref rid="aff2" ref-type="aff">2</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0003-1427-8022</ext-link>
        </contrib>
        <contrib id="contrib9" contrib-type="author" corresp="yes">
          <name name-style="western">
            <surname>Beauchamp</surname>
            <given-names>Marla K</given-names>
          </name>
          <degrees>PT, PhD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <address>
            <institution>School of Rehabilitation Science</institution>
            <institution>McMaster University</institution>
            <addr-line>1400 Main Street West</addr-line>
            <addr-line>Institute for Applied Health Sciences Building</addr-line>
            <addr-line>Hamilton, ON, L8S 1C7</addr-line>
            <country>Canada</country>
            <fax>1 905 524 0069</fax>
            <phone>1 905 525 9140 ext 21732</phone>
            <email>beaucm1@mcmaster.ca</email>
          </address>
          <xref rid="aff3" ref-type="aff">3</xref>
          <xref rid="aff4" ref-type="aff">4</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0003-2843-388X</ext-link>
        </contrib>
      </contrib-group>
      <aff id="aff1">
        <label>1</label>
        <institution>School of Rehabilitation Science</institution>
        <institution>McMaster University</institution>
        <addr-line>Hamilton, ON</addr-line>
        <country>Canada</country>
      </aff>
      <aff id="aff2">
        <label>2</label>
        <institution>Department of Physical Therapy</institution>
        <institution>University of Toronto</institution>
        <addr-line>Toronto, ON</addr-line>
        <country>Canada</country>
      </aff>
      <aff id="aff3">
        <label>3</label>
        <institution>Department of Medicine</institution>
        <institution>McMaster University</institution>
        <addr-line>Hamilton, ON</addr-line>
        <country>Canada</country>
      </aff>
      <aff id="aff4">
        <label>4</label>
        <institution>Research Institute at St Joseph's Healthcare</institution>
        <addr-line>Hamilton, ON</addr-line>
        <country>Canada</country>
      </aff>
      <author-notes>
        <corresp>Corresponding Author: Marla K Beauchamp <email>beaucm1@mcmaster.ca</email></corresp>
      </author-notes>
      <pub-date pub-type="collection">
        <month>10</month>
        <year>2022</year>
      </pub-date>
      <pub-date pub-type="epub">
        <day>31</day>
        <month>10</month>
        <year>2022</year>
      </pub-date>
      <volume>24</volume>
      <issue>10</issue>
      <elocation-id>e36134</elocation-id>
      <history>
        <date date-type="received">
          <day>3</day>
          <month>1</month>
          <year>2022</year>
        </date>
        <date date-type="rev-request">
          <day>19</day>
          <month>4</month>
          <year>2022</year>
        </date>
        <date date-type="rev-recd">
          <day>31</day>
          <month>5</month>
          <year>2022</year>
        </date>
        <date date-type="accepted">
          <day>9</day>
          <month>8</month>
          <year>2022</year>
        </date>
      </history>
      <copyright-statement>©Cassandra D'Amore, Julie C Reid, Matthew Chan, Samuel Fan, Amanda Huang, Jonathan Louie, Andy Tran, Stephanie Chauvin, Marla K Beauchamp. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 31.10.2022.</copyright-statement>
      <copyright-year>2022</copyright-year>
      <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
        <p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Journal of Medical Internet Research, is properly cited. The complete bibliographic information, a link to the original publication on https://www.jmir.org/, as well as this copyright and license information must be included.</p>
      </license>
      <self-uri xlink:href="https://www.jmir.org/2022/10/e36134" xlink:type="simple"/>
      <abstract>
        <sec sec-type="background">
          <title>Background</title>
          <p>This is a systematic review of randomized controlled trials and a meta-analysis comparing smart technology with face-to-face physical activity (PA) interventions in community-dwelling older adults (mean age 60 years).</p>
        </sec>
        <sec sec-type="objective">
          <title>Objective</title>
          <p>This study aims to determine the effect of interventions including smart technology components compared with face-to-face PA interventions on PA and physical function in older adults. The secondary outcomes are depression, anxiety, and health-related quality of life.</p>
        </sec>
        <sec sec-type="methods">
          <title>Methods</title>
          <p>We searched MEDLINE, Embase, CINAHL, and AMED electronic databases from inception to February 2021. Two independent reviewers screened titles, abstracts, and full texts and performed data extraction and risk of bias assessments using the Cochrane risk of bias tool. The Grading of Recommendations Assessment, Development and Evaluation was used to evaluate the quality of the evidence. We provided a narrative synthesis on all included studies and, where possible, performed meta-analyses for similar outcomes.</p>
        </sec>
        <sec sec-type="results">
          <title>Results</title>
          <p>This review included 19 studies with a total of 3455 participants. Random effects meta-analyses showed that interventions with smart technology components resulted in improved step count (mean difference 1440 steps, 95% CI 500-2390) and total PA (standardized mean difference 0.17, 95% CI 0.02-0.32) compared with face-to-face alone. There was no difference between groups in terms of the measures of physical function. Smart technology alone did not show significant differences between groups in any outcome. The quality of the evidence was very low based on the Grading of Recommendations Assessment, Development and Evaluation criteria.</p>
        </sec>
        <sec sec-type="conclusions">
          <title>Conclusions</title>
          <p>Interventions that include smart technology may improve daily step counts by an average of 1440 steps in community-dwelling older adults; however, the quality of the evidence was very low. Future studies are needed to improve the certainty of these results.</p>
        </sec>
        <sec sec-type="Trial Registration">
          <title>Trial Registration</title>
          <p>PROSPERO CRD42020135232; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=135232</p>
        </sec>
      </abstract>
      <kwd-group>
        <kwd>aging</kwd>
        <kwd>exercise</kwd>
        <kwd>mobile health</kwd>
        <kwd>mHealth</kwd>
        <kwd>wearables</kwd>
        <kwd>mobile phone</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec sec-type="introduction">
      <title>Introduction</title>
      <sec>
        <title>Background</title>
        <p>In 2017, the global population of adults aged ≥60 years was 962 million, more than twice the number of older adults in 1980 [<xref ref-type="bibr" rid="ref1">1</xref>]. By 2050, it is expected that the number of older adults will double, reaching nearly 2.1 billion [<xref ref-type="bibr" rid="ref1">1</xref>]. As the population ages, delaying the onset of illness and disability and retaining physical function are top public health priorities [<xref ref-type="bibr" rid="ref2">2</xref>]. Physical activity (PA), defined as any bodily movement produced by skeletal muscles that requires energy expenditure [<xref ref-type="bibr" rid="ref3">3</xref>], is one way to achieve this. However, evidence suggests that 31% of the global population does not meet the recommended levels of PA [<xref ref-type="bibr" rid="ref4">4</xref>,<xref ref-type="bibr" rid="ref5">5</xref>], and inactivity has been identified as a leading risk factor for mortality, accounting for &#62;5 million global deaths annually [<xref ref-type="bibr" rid="ref6">6</xref>]. A recent umbrella review including 24 systematic reviews reported that older adults that are physically active have a lower risk of all-cause and cardiovascular mortality, breast and prostate cancer, fractures, disabilities with activities of daily living, functional limitations, risk of falling, cognitive decline, dementia, Alzheimer disease, and depression [<xref ref-type="bibr" rid="ref7">7</xref>]. In 2018, the World Health Organization released their global action plan on PA to combat inactivity and improve health over the next decade [<xref ref-type="bibr" rid="ref8">8</xref>].</p>
        <p>In late 2019, SARS-CoV-2, which causes COVID-19 disease, emerged and quickly became an international health crisis, and in March 2020, the World Health Organization declared COVID-19 a global pandemic [<xref ref-type="bibr" rid="ref9">9</xref>]. Since then, many countries have established strict public health measures to curb the spread of the disease, including social distancing and isolation. Although these measures have the benefit of minimizing viral transmission, which is critical for older adults who are at a higher risk for more severe illness [<xref ref-type="bibr" rid="ref10">10</xref>,<xref ref-type="bibr" rid="ref11">11</xref>], they have also exacerbated levels of physical inactivity. A systematic review including 66 studies with nearly 87,000 participants from 26 countries reported significant declines in PA during the lockdown owing to the COVID-19 pandemic [<xref ref-type="bibr" rid="ref12">12</xref>]. Unfortunately, older adults are also at a higher risk for consequences of inactivity, such as frailty, sarcopenia, and chronic diseases, compared with their younger counterparts [<xref ref-type="bibr" rid="ref13">13</xref>]. These data highlight an urgent need to evaluate alternative methods of improving PA levels. Fortunately, with advancements in technology, smart technology has become an increasingly relevant and studied tool for achieving health objectives [<xref ref-type="bibr" rid="ref14">14</xref>,<xref ref-type="bibr" rid="ref15">15</xref>]. Smart technology interventions may represent an ideal alternative to traditional face-to-face programs as they have the potential to overcome service delivery barriers such as limited access; inconvenience of travel; absenteeism from work and family [<xref ref-type="bibr" rid="ref16">16</xref>]; and, now importantly, minimizing unnecessary exposure to COVID-19 for those who are most at risk. The role of smart technology in improving PA in older adults warrants further evaluation both now and for informing future directions of health care delivery.</p>
        <p>Smart technology capitalizes on communication and information technologies (eg, internet and video calls) [<xref ref-type="bibr" rid="ref14">14</xref>] and uses different mediums, such as computers and tablets, or mobile health, which includes smartphones, wearables (eg, FitBit), and mobile apps (eg, My Fitness Pal, Samsung Health, and Apple Health) [<xref ref-type="bibr" rid="ref17">17</xref>]. Systematic reviews have demonstrated that smart technology interventions can improve PA levels, specifically steps per day and minutes per day of moderate to vigorous PA in generally healthy older adult populations (mean age ≥55 years) [<xref ref-type="bibr" rid="ref18">18</xref>-<xref ref-type="bibr" rid="ref21">21</xref>]. However, there are still unanswered questions and a need for more and better evidence. For example, existing reviews have examined only specific types of smart technology [<xref ref-type="bibr" rid="ref20">20</xref>] or included only digital PA estimates without considering participant-oriented outcomes [<xref ref-type="bibr" rid="ref19">19</xref>]. Importantly, existing systematic reviews have not compared smart technology PA interventions with more traditional modes of PA intervention delivery (ie, face-to-face) [<xref ref-type="bibr" rid="ref15">15</xref>,<xref ref-type="bibr" rid="ref20">20</xref>-<xref ref-type="bibr" rid="ref23">23</xref>]. This comparison is essential for determining whether interventions that include smart technology components are more, less, or as effective as face-to-face alone interventions. Therefore, the purpose of this review is to determine the effects of PA interventions that use smart technology compared with face-to-face PA interventions on PA and physical function in community-dwelling older adults.</p>
      </sec>
      <sec>
        <title>Review Question</title>
        <p>This systematic review will answer whether the PA interventions that use smart technology are more, less, or as effective as face-to-face alone interventions for increasing PA and function in older adults. The secondary questions were as follows: (1) What are the effects of smart technology PA interventions on secondary outcomes, including health-related quality of life (HRQoL), anxiety, and depression? and (2) Does the effectiveness of smart technology interventions differ by type of PA or by the type of smart technology used (eg, wearable vs mobile app)?</p>
      </sec>
    </sec>
    <sec sec-type="methods">
      <title>Methods</title>
      <sec>
        <title>Overview</title>
        <p>This systematic review was conducted in accordance with a peer-reviewed protocol [<xref ref-type="bibr" rid="ref24">24</xref>] registered in PROSPERO (CRD42020135232) and followed the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analysis) guidelines [<xref ref-type="bibr" rid="ref25">25</xref>]. The full protocol has been published elsewhere [<xref ref-type="bibr" rid="ref24">24</xref>].</p>
      </sec>
      <sec>
        <title>Data Source and Searches</title>
        <p>A comprehensive search of the MEDLINE, Embase, CINAHL, and AMED databases from inception to February 2021 was conducted after consultation with a health research librarian [<xref ref-type="bibr" rid="ref26">26</xref>]. The full search strategies are available in <xref ref-type="supplementary-material" rid="app1">Multimedia Appendix 1</xref> [<xref ref-type="bibr" rid="ref27">27</xref>-<xref ref-type="bibr" rid="ref45">45</xref>]; common Medical Subject Headings across databases included age, technology, physical fitness, with keywords to capture all types of PA and smart technology. Reference lists of included studies were hand searched to identify additional relevant studies.</p>
      </sec>
      <sec>
        <title>Study Selection</title>
        <sec>
          <title>Overview</title>
          <p>Two independent reviewers completed screening for both the titles and abstracts and full-text articles using the web-based referencing software system Covidence (Veritas Health Innovation). Disagreements were resolved by consensus or arbitration by a third reviewer as necessary.</p>
        </sec>
        <sec>
          <title>Inclusion Criteria</title>
          <p>We included studies that met the following criteria: (1) community-dwelling older adults with a mean age of ≥60 years [<xref ref-type="bibr" rid="ref46">46</xref>], (2) interventions that promoted PA using smart technology, (3) face-to-face interventions in comparator groups, (4) a primary outcome measure of PA or physical function, and (5) randomized controlled trials (RCTs) published in English in a peer-reviewed journal.</p>
        </sec>
        <sec>
          <title>Exclusion Criteria</title>
          <p>We excluded studies that evaluated participants admitted to an inpatient unit in a hospital or long-term care home, interventions that only used audio phone calls (ie, with no video or SMS text messaging equivalent to the use of a landline), video games, or virtual reality. Studies that used a quasi-experimental design were also excluded.</p>
        </sec>
      </sec>
      <sec>
        <title>Data Extraction and Risk of Bias</title>
        <p>Data from the included studies were extracted independently and in duplicate using a standardized data collection form [<xref ref-type="bibr" rid="ref24">24</xref>]. Two reviewers independently assessed studies using the Cochrane risk of bias tool [<xref ref-type="bibr" rid="ref47">47</xref>] and the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system [<xref ref-type="bibr" rid="ref48">48</xref>].</p>
      </sec>
      <sec>
        <title>Data Synthesis and Analysis</title>
        <p>Meta-analyses for primary and secondary outcomes were conducted using random effects models with standardized mean difference (SMD) and mean difference (MD) where appropriate in Review Manager (RevMan; version 5.4, The Cochrane Collaboration, 2020) [<xref ref-type="bibr" rid="ref24">24</xref>]. According to the Cochrane handbook, when necessary, we converted scales to correct for the difference in direction [<xref ref-type="bibr" rid="ref49">49</xref>], and median and IQR were converted following the methods of Wan et al [<xref ref-type="bibr" rid="ref50">50</xref>]. When possible, we performed sensitivity analyses by removing studies with an overall rating of a high risk of bias for each outcome. This deviates from the initial protocol, wherein we planned to remove only studies with a high risk of bias in ≥3 domains. Where appropriate, we completed subgroup analyses for our secondary questions. Where possible, we completed analyses for interventions that used smart technology alone compared with face-to-face alone.</p>
      </sec>
    </sec>
    <sec sec-type="results">
      <title>Results</title>
      <sec>
        <title>Overview</title>
        <p>We identified 12,245 records from our search; reviewers screened 9434 titles and abstracts after duplicate removal, and 19 RCTs were eligible for inclusion (<xref rid="figure1" ref-type="fig">Figure 1</xref>). The reasons for full-text exclusion are provided in <xref ref-type="supplementary-material" rid="app1">Multimedia Appendix 1</xref>. Reviewers attempted to contact 7 corresponding authors for missing information, and 1 author responded. All the studies were combined in a narrative synthesis, evaluating a total of 3455 participants. A total of 18 RCTs with 3405 participants randomized to either a smart technology or face-to-face intervention were included in the quantitative analysis.</p>
        <p>Characteristics of the studies are shown in <xref ref-type="table" rid="table1">Tables 1</xref>-<xref ref-type="table" rid="table2">2</xref>. Of the 3455 participants, 1874 (54.24%) were female, and the mean age ranged from 60 to 72 years. Studies were conducted at outpatient or community practices in the following countries: United States (6/19, 32%); Belgium (2/19, 11%); Netherlands (2/19, 11%); United Kingdom (2/19, 11%); and one each in Australia, Chile, Denmark, Finland, Hong Kong, New Zealand, and Spain. Participants were community-dwelling older adults, with 14 studies focused on specific clinical populations, including people with chronic obstructive pulmonary disease (COPD) [<xref ref-type="bibr" rid="ref27">27</xref>-<xref ref-type="bibr" rid="ref31">31</xref>], cardiovascular disease [<xref ref-type="bibr" rid="ref32">32</xref>-<xref ref-type="bibr" rid="ref35">35</xref>], diabetes [<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref37">37</xref>], knee arthritis [<xref ref-type="bibr" rid="ref38">38</xref>,<xref ref-type="bibr" rid="ref39">39</xref>], obesity [<xref ref-type="bibr" rid="ref40">40</xref>], and cognitive impairment plus physical frailty [<xref ref-type="bibr" rid="ref41">41</xref>].</p>
        <fig id="figure1" position="float">
          <label>Figure 1</label>
          <caption>
            <p>PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analysis) flow diagram of evidence search and selection.</p>
          </caption>
          <graphic xlink:href="jmir_v24i10e36134_fig1.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
        </fig>
        <table-wrap position="float" id="table1">
          <label>Table 1</label>
          <caption>
            <p>Characteristics of included studies with author names beginning with A to J.</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="100"/>
            <col width="160"/>
            <col width="200"/>
            <col width="180"/>
            <col width="180"/>
            <col width="180"/>
            <thead>
              <tr valign="top">
                <td>Study and country</td>
                <td>Population, sample size (n)</td>
                <td>Intervention<sup>a</sup></td>
                <td>Usual care</td>
                <td>Outcomes</td>
                <td>Key findings</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td>Alonso-Domínguez et al [<xref ref-type="bibr" rid="ref36">36</xref>], 2019, Spain</td>
                <td>T2DM<sup>b</sup>, median age IG<sup>c</sup>=60.8 (IQR 7.8) years; CG<sup>d</sup>=60.4 (8.4) years, 45.6% female, n=204</td>
                <td>[Smartphone app] Daily use of mobile app for 3 months + heart-healthy 4-km walks once per week for 5 weeks</td>
                <td>10-minute standardized counseling session on PA<sup>e</sup> and healthy diet; information leaflet provided</td>
                <td>PA: steps per day measured by pedometer; weekly PA measured by IPAQ<sup>f</sup>-Spanish version</td>
                <td>Significant increase in daily steps per day (<italic>P</italic>&#60;.05 at 3 and 12 months), aerobic steps (<italic>P</italic>&#60;.05 at 3 months), distance walked (<italic>P</italic>&#60;.05 at 3 months), and total PA (<italic>P</italic>&#60;.05 at 3 months) for intervention group</td>
              </tr>
              <tr valign="top">
                <td>Armit et al [<xref ref-type="bibr" rid="ref43">43</xref>], 2005, Australia</td>
                <td>Community-dwelling older adults (55-70 years), mean age 64 (SD 4.6) years, 64.9% female, n=37 recruited, 28 with 1 assessment</td>
                <td>[Pedometer] Pedometer use for 12 weeks; counseling session; information booklet; diary for goal setting and self-monitoring; 3 follow-up phone calls to reevaluate, reinforce, and discuss adherence issues</td>
                <td>Counseling session; information booklet; diary for goal setting and self-monitoring; 3 follow-up phone calls to reevaluate, reinforce, and discuss adherence issues</td>
                <td>PA: self-report survey<sup>g</sup></td>
                <td>No significant difference in PA between groups at either time point</td>
              </tr>
              <tr valign="top">
                <td>Audsley et al [<xref ref-type="bibr" rid="ref44">44</xref>], 2020, United Kingdom</td>
                <td>Community-dwelling older adults from Falls Management program, mean age IG=76.9 (SD 7.0) years; CG=73.8 (SD 6.4) years, 73.3% female, n=50</td>
                <td>[Pedometer] 6 sessions of 60 to 90 minutes of motivational interviewing and behavior change techniques over 6 months; pedometer use worksheets with PA diaries + usual care</td>
                <td>24-week group exercise program (strength, balance, cardiovascular, and flexibility exercises) + 30-minute 2 times per week home exercise program; how to get up from a fall and strategies to reduce inactivity</td>
                <td>PA: weekly MVPA<sup>h</sup> measured by Phone-FITT<sup>i</sup> questionnaire</td>
                <td>No significant differences in MVPA between groups</td>
              </tr>
              <tr valign="top">
                <td>Barnason et al [<xref ref-type="bibr" rid="ref32">32</xref>], 2009, United States</td>
                <td>Postoperative CABS<sup>j</sup> (aged &#62;65 years), mean age 71.2 (SD 4.9) years, 17% female, n=280</td>
                <td>[Telerehabilitation] Telehealth symptom management for 6 weeks on strategies to address common symptoms after CABS and improve outcomes (eg, PA and functioning) + usual care</td>
                <td>Usual care not defined</td>
                <td>PA: modified 7-day Activity Interview; activity counts by accelerometer; Physical Activity and Exercise Diary; quality of life: MOS SF-36<sup>k</sup></td>
                <td>Higher overall energy expenditure in usual care group, except at 3 weeks where intervention group had higher expenditure; no other significant differences</td>
              </tr>
              <tr valign="top">
                <td>Christiansen et al [<xref ref-type="bibr" rid="ref38">38</xref>], 2020, United States</td>
                <td>Unilateral TKR<sup>l</sup> (aged &#62;45 years), mean age 67 (SD 7.0) years, 53.4% female, n=43</td>
                <td>[Wearable] 6-month standard outpatient PT<sup>m</sup> with a Fitbit Zip, weekly steps per day goal from a PT, 6 monthly phone calls from a research assistant</td>
                <td>Standard outpatient PT, including printed home exercise program; 6 monthly phone calls after discharge discussing overall health</td>
                <td>PA: steps per day and MVPA per week measured by Actigraph</td>
                <td>Increased steps and minutes per week in MVPA for intervention group at both follow-ups</td>
              </tr>
              <tr valign="top">
                <td>de Blok et al [<xref ref-type="bibr" rid="ref27">27</xref>], 2006, Netherlands</td>
                <td>COPD<sup>n</sup> (aged 40-85 years), mean age IG=65 (SD 10.4) years, CG=62.5 (SD 12.3) years, 75% female, n=21</td>
                <td>[Pedometer] 4 sessions of 30-minute exercise counseling (steps per day goal setting), pedometer feedback for 10 weeks + usual care</td>
                <td>Conventional pulmonary rehabilitation of exercise training, dietary intervention, and psychoeducational modules over 9 weeks</td>
                <td>PA: pedometer steps per day<sup>g</sup>; function: chair stand, arm curl, 8-foot up-and-go, 2-minute step test; other: Beck Depression Inventory</td>
                <td>Significantly improved 8-foot up-and-go test and 2-minute step test for intervention group; no significant differences between groups in steps per day</td>
              </tr>
              <tr valign="top">
                <td>Frederix et al [<xref ref-type="bibr" rid="ref33">33</xref>], 2015, Belgium</td>
                <td>Cardiac conditions (CAD<sup>o</sup> and CHF<sup>p</sup>), mean age 61 (SD 8.5) years, 17% female, n=140</td>
                <td>[Multicomponent] 24-week PA telerehabilitation; exercise training protocols + center-based cardiac rehabilitation for 12 weeks (usual care)</td>
                <td>Center-based cardiac rehabilitation for 12 weeks (45 sessions—2 exercise sessions per week, dietary consultation, and psychologist session)</td>
                <td>PA: CPET<sup>q</sup> VO<sub>2</sub><sup>r</sup> peak<sup>g</sup>, accelerometer PA, self-report IPAQ converted to MET<sup>s</sup>-minutes per week of MVPA; quality of life: HeartQoL</td>
                <td>Significant improvement in mean VO<sub>2</sub> peak (<italic>P</italic>&#60;.001), steps per day, MET-minutes per week of MVPA (<italic>P</italic>=.01), and health-related QoL<sup>t</sup> (<italic>P</italic>=.01) for intervention group</td>
              </tr>
              <tr valign="top">
                <td>Hansen et al [<xref ref-type="bibr" rid="ref28">28</xref>], 2000, Denmark</td>
                <td>COPD (no participation in pulmonary rehabilitation in the preceding 6 months), mean age 68.3 (SD 9.0) years, 55% female, n=134</td>
                <td>[Telerehabilitation] 10-week telerehabilitation program including group-based supervised, standardized 35-minute exercise program via videoconference, followed by 20 minutes of patient education 3 times per week</td>
                <td>10-week conventional pulmonary rehabilitation program including group-based supervised, standardized 60-minute exercise program 2 times per week in conjunction with 1 time per week education session lasting 60-90 minutes</td>
                <td>PA: accelerometer PA; function: 6MWT<sup>g,u</sup>, 30-second sit-to-stand; quality of life: HADS<sup>v</sup>, EQ-5D<sup>w;</sup> COPD: COPD assessment test and Clinical COPD Questionnaire</td>
                <td>No significant differences in 6MWT; however, intervention group maintained improvement at 22 weeks; significantly improved HADS and depression scores (<italic>P</italic>&#60;.05) and COPD Assessment Test scores (<italic>P</italic>=.04) in intervention group</td>
              </tr>
            </tbody>
          </table>
          <table-wrap-foot>
            <fn id="table1fn1">
              <p><sup>a</sup>The authors grouped interventions by the type of smart technology; groupings are indicated in square brackets at the beginning of each intervention description.</p>
            </fn>
            <fn id="table1fn2">
              <p><sup>b</sup>T2DM: type 2 diabetes mellitus.</p>
            </fn>
            <fn id="table1fn3">
              <p><sup>c</sup>IG: intervention group.</p>
            </fn>
            <fn id="table1fn4">
              <p><sup>d</sup>CG: control group.</p>
            </fn>
            <fn id="table1fn5">
              <p><sup>e</sup>PA: physical activity.</p>
            </fn>
            <fn id="table1fn6">
              <p><sup>f</sup>IPAQ: International Physical Activity Questionnaire.</p>
            </fn>
            <fn id="table1fn7">
              <p><sup>g</sup>Primary outcomes of the individual studies.</p>
            </fn>
            <fn id="table1fn8">
              <p><sup>h</sup>MVPA: moderate to vigorous physical activity.</p>
            </fn>
            <fn id="table1fn9">
              <p><sup>i</sup>FITT: Frequency, intensity, type, and time</p>
            </fn>
            <fn id="table1fn10">
              <p><sup>j</sup>CABS: coronary artery bypass surgery.</p>
            </fn>
            <fn id="table1fn11">
              <p><sup>k</sup>MOS SF-36: Medical Outcomes Study 36-item Short Form survey.</p>
            </fn>
            <fn id="table1fn12">
              <p><sup>l</sup>TKR: total knee replacement.</p>
            </fn>
            <fn id="table1fn13">
              <p><sup>m</sup>PT: physiotherapy.</p>
            </fn>
            <fn id="table1fn14">
              <p><sup>n</sup>COPD: chronic obstructive pulmonary disease.</p>
            </fn>
            <fn id="table1fn15">
              <p><sup>o</sup>CAD: coronary artery disease.</p>
            </fn>
            <fn id="table1fn16">
              <p><sup>p</sup>CHF: congestive heart failure</p>
            </fn>
            <fn id="table1fn17">
              <p><sup>q</sup>CPET: cardiopulmonary exercise testing.</p>
            </fn>
            <fn id="table1fn18">
              <p><sup>r</sup>VO<sub>2</sub>: maximal oxygen uptake.</p>
            </fn>
            <fn id="table1fn19">
              <p><sup>s</sup>MET: metabolic equivalent.</p>
            </fn>
            <fn id="table1fn20">
              <p><sup>t</sup>QoL: quality of life.</p>
            </fn>
            <fn id="table1fn21">
              <p><sup>u</sup>6MWT: 6-minute walk test.</p>
            </fn>
            <fn id="table1fn22">
              <p><sup>v</sup>HADS: Hospital Anxiety and Depression Scale.</p>
            </fn>
            <fn id="table1fn23">
              <p><sup>w</sup>EQ-5D: EuroQoL 5 Dimensions.</p>
            </fn>
          </table-wrap-foot>
        </table-wrap>
        <table-wrap position="float" id="table2">
          <label>Table 2</label>
          <caption>
            <p>Characteristics of included studies with author names beginning with K to Z.</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="100"/>
            <col width="160"/>
            <col width="200"/>
            <col width="180"/>
            <col width="180"/>
            <col width="180"/>
            <thead>
              <tr valign="top">
                <td>Study and country</td>
                <td>Population, sample size (n)</td>
                <td>Intervention<sup>a</sup></td>
                <td>Usual care</td>
                <td>Outcomes</td>
                <td>Key findings</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td>Kawagoshi et al [<xref ref-type="bibr" rid="ref29">29</xref>], 2015, Finland</td>
                <td>COPD, mean age IG=74 (SD 8) years; CG=75 (SD 9) years, 11% female, n=39</td>
                <td>[Pedometer] Pedometer + home-based pulmonary rehabilitation including breathing retraining, exercise training, respiratory training, and monthly 45-minute education sessions</td>
                <td>Home-based pulmonary rehabilitation including breathing retraining, exercise training, respiratory muscle training, and monthly 45-minute education sessions</td>
                <td>PA: total PA as measured by accelerometer; function: quadriceps muscle force; 6MWT; Pulmonary: Chronic Respiratory Disease Questionnaire</td>
                <td>Significant increase in walking time (<italic>P</italic>=.04), dyspnea, and quadriceps force in intervention group; significant improvements in pulmonary function tests, 6-minute walk distance, and Chronic Respiratory Disease Questionnaire in both groups</td>
              </tr>
              <tr valign="top">
                <td>King et al [<xref ref-type="bibr" rid="ref42">42</xref>], 2020, United States</td>
                <td>Community-dwelling adults aged 50 years, mean age 62.3 (SD 8.4) years, 78.8% female, n=245</td>
                <td>[Telerehabilitation] 1:1 initial counseling session, pedometer use; additional (up to 28) 10 to 15 minutes counseling sessions by a virtual advisor over 12 months</td>
                <td>1:1 initial counseling session, pedometer use; additional (up to 28) 10 to 15 minutes counseling sessions conducted by a human advisor over 12 months</td>
                <td>PA: walking minutes per week<sup>b</sup> total PA, MVPA, daily PA measured by accelerometer, self-report weekly sedentary behavior; quality of life: Vitality Plus scale</td>
                <td>Significantly increased steps per day (<italic>P</italic>=.02) in intervention group; significant decreases in both groups for reported sedentary time</td>
              </tr>
              <tr valign="top">
                <td>Kwan et al [<xref ref-type="bibr" rid="ref41">41</xref>], 2020, Hong Kong</td>
                <td>Mild cognitive impairment and physical frailty, mean age 71.0 (SD 9.0) years, 85% female, n=33</td>
                <td>[Smartphone app] Smartphone apps for individualized goals, to log PA data, performance reviews, and e-reminders; communication app for e-coaching, personalization of goal settings, and messages of praise + control intervention; all interventions were for 12 weeks</td>
                <td>Conventional behavior change techniques via PA counseling, telephone follow-up, health education, and exercise training. All interventions were for 12 weeks</td>
                <td>PA: steps per day measured by accelerometer; MVPA and non-MVPA per week measured by accelerometer; other: Fried frailty index; MoCA<sup>c</sup></td>
                <td>Significant increase in MVPA (<italic>P</italic>=.04), walking time (<italic>P</italic>=.03), steps per day (<italic>P</italic>=.02), brisk walking (<italic>P</italic>=.009), and peak cadence (<italic>P</italic>=.003) for intervention group; adherence to face-to-face sessions was 100% for both groups; smartphone compliance was 54.1 (SD 1.2) days per participant (range 0-56 days)</td>
              </tr>
              <tr valign="top">
                <td>Maddison et al [<xref ref-type="bibr" rid="ref34">34</xref>], 2015, New Zealand</td>
                <td>Ischemic heart disease, mean age 60.2 (SD 9.3) years, 19% female, n=171</td>
                <td>[Multicomponent] Automated text messages for 24 weeks encouraging 30 minutes per day MVPA 5 days per week + regular exercise prescription, behavior change strategies, website access with model vignettes, self-monitoring, information</td>
                <td>Encouraged to participate in cardiac rehabilitation typically including education sessions, psychological support, and PA encouragement and offer to join a supervised exercise club</td>
                <td>PA: self-reported PA measured by IPAQ; other: PVO<sub>2</sub><sup>d</sup> assessed during CPET<sup>b</sup>; self-efficacy and motivation to exercise; SF-36 and EQ-5D</td>
                <td>No significant difference in PVO<sub>2</sub> between groups; significant improvements in self-report PA (<italic>P</italic>=.05), walking (<italic>P</italic>=.02), self-efficacy (<italic>P</italic>=.04), and health-related QoL (<italic>P</italic>=.03) in intervention group</td>
              </tr>
              <tr valign="top">
                <td>Mendoza et al [<xref ref-type="bibr" rid="ref30">30</xref>], 2020, Chile</td>
                <td>Stable COPD, mean age 68.7 (SD 8.5) years, 39.2% female, n=102</td>
                <td>[Pedometer] Pedometer use and steps per day goals for 3 months, 3 monthly follow-up sessions with a physician and physiotherapist to increase step count</td>
                <td>3 monthly counseling sessions with physician and PT to increase PA, advised to walk minimum 30 minutes per day</td>
                <td>PA: steps per day<sup>b</sup> measured by pedometer; other: health status and exercise capacity</td>
                <td>Significant increase in PA (<italic>P</italic>&#60;.001) and exercise capacity (<italic>P</italic>=.03) in intervention group</td>
              </tr>
              <tr valign="top">
                <td>Mouton and Cloes [<xref ref-type="bibr" rid="ref45">45</xref>], 2015, Belgium</td>
                <td>Community-dwelling adults (aged 50 years), mean age IG1=61.2 (SD 6.3) years; IG2=69.8 (SD 7.4) years; IG3=63.2 (SD 5.7) years; CG=66.1 (SD 6.8) years, 60% female, n=149</td>
                <td>[Website] Three groups, all 3-month duration: (1) web-based intervention (PA promotion + monthly PA feedback); (2) center-based intervention—12 weekly sessions of group exercise; and (3) mixed intervention (web- and center-based intervention)</td>
                <td>No intervention received</td>
                <td>PA: self-report using IPAQ-S<sup>e</sup>; other: stages of change; awareness of PA; and participant acceptance of intervention</td>
                <td>Mixed intervention increased PA level (<italic>P</italic>=.04); center-based intervention (<italic>P</italic>&#60;.001) and mixed intervention (<italic>P</italic>=.01) increased PA stages of change; web-based intervention (<italic>P</italic>=.02) and mixed intervention (<italic>P</italic>&#60;.001) increased PA awareness</td>
              </tr>
              <tr valign="top">
                <td>Roberts et al [<xref ref-type="bibr" rid="ref35">35</xref>], 2019, United States</td>
                <td>Community-dwelling adults (aged 60 years) with moderate to high risk of CVD<sup>f</sup> events, mean age 72 (SD 7.4) years, 60% female, n=40</td>
                <td>[Wearable] Activity tracker + strategies to increase PA for 20 weeks; usual care (8-week center-based exercise intervention); goal to achieve 150 minutes of MVPA per week for 12 weeks; encouragement of nonexercise PA</td>
                <td>Usual care including 2 for per week center-based exercise intervention for 8 weeks; instruction to achieve 150 minutes of MVPA per week for remaining 12 weeks; behavioral counseling to encourage nonexercise PA</td>
                <td>PA: daily activity measured by accelerometer; function: 6MWT; 4-meter gait speed; grip strength; SPPB<sup>g</sup></td>
                <td>Significant increase in steps per day for intervention group</td>
              </tr>
              <tr valign="top">
                <td>Tabak et al [<xref ref-type="bibr" rid="ref31">31</xref>], 2014, Netherlands</td>
                <td>Stable COPD, mean age IG=65.2 (SD 9.0) years; CG=67.9 (SD 5.7) years, 37% female, n=34</td>
                <td>[Multicomponent] 4-week daily use of mobile activity coach for feedback, motivation, and target PA levels + usual care (medication and PT—weekly group training sessions)</td>
                <td>Could consist of medication and weekly group training PT sessions</td>
                <td>PA: steps per day<sup>b</sup> measured by pedometer; COPD: Clinical COPD Questionnaire (health status); other: compliance</td>
                <td>No significant differences in steps per day; nonsignificant improvement in health status in intervention group; 86% adhered to the activity coach</td>
              </tr>
              <tr valign="top">
                <td>Talbot et al [<xref ref-type="bibr" rid="ref39">39</xref>], 2003, United States</td>
                <td>Symptomatic knee OA<sup>h</sup>, aged ≥60 years, mean age IG=69.6 (SD 6.7) years; CG=70.8 (SD 4.7) years, 76.5% female, n=34</td>
                <td>[Pedometer] Pedometer use + daily step goals; education booklet on exercise and managing pain; usual care (12 sessions of 1-hour arthritis self-management education)</td>
                <td>12 sessions of 1-hour arthritis self-management education (including a session on exercise)</td>
                <td>PA: steps per day<sup>b</sup> by pedometer, PA over time (accelerometer); function: leg muscle strength; 100-foot timed walk-turn-walk; timed stair climb; timed chair rise</td>
                <td>23% steps per day increase for intervention group vs 15% decrease in control group; improved usual pace gait speed (<italic>P</italic>=.04) and isometric leg strength (21%—compared with 3.5% loss in control group)</td>
              </tr>
              <tr valign="top">
                <td>Weinstock et al [<xref ref-type="bibr" rid="ref37">37</xref>], 2011, United States</td>
                <td>Diabetes mellitus, mean age 70.9 (SD 6.8) years, 63% female, n=1650</td>
                <td>[Multicomponent] Educational videoconferencing for 4-6 weeks to review blood glucose and blood pressure measurements; pedometer use with goals set for 2 years</td>
                <td>Usual care from PCP<sup>i</sup>; PA encouraged by pedometer use with goals set between participant and PCP for 2 years</td>
                <td>PA: diabetes self-care activities for assessment of PA; other: feasibility; acceptability; and CARE Depression Instrument</td>
                <td>Significantly slower rate of decline in PA (<italic>P</italic>=.01) and lower rate of PI<sup>j</sup> (0.04); significantly higher PA levels (<italic>P</italic>&#60;.001) in intervention group</td>
              </tr>
              <tr valign="top">
                <td>Yates et al [<xref ref-type="bibr" rid="ref40">40</xref>], 2009, United Kingdom</td>
                <td>Overweight or obese (BMI ≥25), mean age 65 (SD 8) years, 34% female, n=87</td>
                <td>[Pedometer] Pedometer use + 180-minute education session on causes and complications of impaired glucose tolerance + exercise information</td>
                <td>Two groups: (1) Same education session as intervention but no pedometer and (2) usual care—information pamphlet</td>
                <td>PA: steps per day measured by pedometer, self-reported walking by IPAQ, and total MVPA</td>
                <td>Compared with usual care group 2, significant increases in steps per day, self-reported walking, and total MVPA at 3, 6, and 12 months in intervention group (all <italic>P</italic>&#60;.05)</td>
              </tr>
            </tbody>
          </table>
          <table-wrap-foot>
            <fn id="table2fn1">
              <p><sup>a</sup>The authors grouped interventions by the type of smart technology; groupings are indicated in square brackets at the beginning of each intervention description.</p>
            </fn>
            <fn id="table2fn2">
              <p><sup>b</sup>Primary outcomes of the individual studies.</p>
            </fn>
            <fn id="table2fn3">
              <p><sup>c</sup>MoCA: Montreal Cognitive Assessment.</p>
            </fn>
            <fn id="table2fn4">
              <p><sup>d</sup>PVO<sub>2</sub>: peak oxygen uptake.</p>
            </fn>
            <fn id="table2fn5">
              <p><sup>e</sup>IPAQ-S: International Physical Activity Questionnaire-Short.</p>
            </fn>
            <fn id="table2fn6">
              <p><sup>f</sup>CVD: cardiovascular disease.</p>
            </fn>
            <fn id="table2fn7">
              <p><sup>g</sup>SPPB: Short Performance Physical Battery.</p>
            </fn>
            <fn id="table2fn8">
              <p><sup>h</sup>OA: osteoarthritis.</p>
            </fn>
            <fn id="table2fn9">
              <p><sup>i</sup>PCP: primary care provider.</p>
            </fn>
            <fn id="table2fn10">
              <p><sup>j</sup>PI: physical impairment.</p>
            </fn>
          </table-wrap-foot>
        </table-wrap>
      </sec>
      <sec>
        <title>Interventions</title>
        <p>Detailed descriptions of the smart technology interventions in each study are provided in <xref ref-type="supplementary-material" rid="app1">Multimedia Appendix 1</xref>. A total of 16 studies included a single smart technology component, including smartphone apps [<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref41">41</xref>], wearable activity trackers (eg, Fitbit) [<xref ref-type="bibr" rid="ref35">35</xref>,<xref ref-type="bibr" rid="ref38">38</xref>], telerehabilitation (eg, video conferencing, virtual advisor, or health buddy device) [<xref ref-type="bibr" rid="ref28">28</xref>,<xref ref-type="bibr" rid="ref32">32</xref>,<xref ref-type="bibr" rid="ref42">42</xref>], and pedometers (ie, only provides step counts) [<xref ref-type="bibr" rid="ref27">27</xref>,<xref ref-type="bibr" rid="ref29">29</xref>,<xref ref-type="bibr" rid="ref30">30</xref>,<xref ref-type="bibr" rid="ref39">39</xref>,<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref43">43</xref>,<xref ref-type="bibr" rid="ref44">44</xref>], whereas the remaining 3 had multiple components, including video conference and pedometer [<xref ref-type="bibr" rid="ref37">37</xref>]; website and SMS text messaging [<xref ref-type="bibr" rid="ref34">34</xref>]; and website plus pedometer, SMS text messaging, and email [<xref ref-type="bibr" rid="ref33">33</xref>]. A total of 15 studies included smart technology and a face-to-face component in the intervention group [<xref ref-type="bibr" rid="ref27">27</xref>,<xref ref-type="bibr" rid="ref29">29</xref>-<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref38">38</xref>-<xref ref-type="bibr" rid="ref41">41</xref>,<xref ref-type="bibr" rid="ref43">43</xref>,<xref ref-type="bibr" rid="ref44">44</xref>]. Furthermore, 4 studies evaluated smart technology alone versus face-to-face alone [<xref ref-type="bibr" rid="ref28">28</xref>,<xref ref-type="bibr" rid="ref37">37</xref>,<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref45">45</xref>]. The length of interventions ranged from 10 weeks [<xref ref-type="bibr" rid="ref27">27</xref>] to 1 year [<xref ref-type="bibr" rid="ref29">29</xref>], and follow-ups ranged from 6 weeks [<xref ref-type="bibr" rid="ref32">32</xref>] to 2 years [<xref ref-type="bibr" rid="ref37">37</xref>].</p>
      </sec>
      <sec>
        <title>Risk of Bias</title>
        <p>Overall, the risk of bias was a concern for studies included in this review. On the basis of the outcome with the highest risk of bias (ie, if we assessed risk of bias for 3 outcomes in a study and 1 of those was rated a high risk of bias and the other 2 were some concerns, we rated the study as high risk of bias), 14 studies were judged to be high risk [<xref ref-type="bibr" rid="ref27">27</xref>,<xref ref-type="bibr" rid="ref29">29</xref>,<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref32">32</xref>,<xref ref-type="bibr" rid="ref34">34</xref>,<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref37">37</xref>,<xref ref-type="bibr" rid="ref39">39</xref>-<xref ref-type="bibr" rid="ref45">45</xref>], 4 studies had some concerns [<xref ref-type="bibr" rid="ref28">28</xref>,<xref ref-type="bibr" rid="ref30">30</xref>,<xref ref-type="bibr" rid="ref35">35</xref>,<xref ref-type="bibr" rid="ref38">38</xref>], and 1 study had a low risk of bias [<xref ref-type="bibr" rid="ref33">33</xref>]. The areas of greatest concerns were missing outcome data (10/19, 53% high risk) and risk of bias related to measurement of the outcome (eg, awareness of intervention and influence of knowledge of intervention on the assessment; 9/19, 47% high risk). A summary figure is available in <xref ref-type="supplementary-material" rid="app1">Multimedia Appendix 1</xref>.</p>
      </sec>
      <sec>
        <title>Physical Activity</title>
        <sec>
          <title>Overview</title>
          <p>All included studies assessed the effect of smart technology interventions on PA [<xref ref-type="bibr" rid="ref27">27</xref>-<xref ref-type="bibr" rid="ref45">45</xref>]. The types of PA evaluated included steps per day [<xref ref-type="bibr" rid="ref27">27</xref>,<xref ref-type="bibr" rid="ref28">28</xref>,<xref ref-type="bibr" rid="ref30">30</xref>,<xref ref-type="bibr" rid="ref33">33</xref>,<xref ref-type="bibr" rid="ref35">35</xref>,<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref38">38</xref>-<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref42">42</xref>], total PA [<xref ref-type="bibr" rid="ref28">28</xref>,<xref ref-type="bibr" rid="ref33">33</xref>,<xref ref-type="bibr" rid="ref34">34</xref>,<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref37">37</xref>,<xref ref-type="bibr" rid="ref41">41</xref>-<xref ref-type="bibr" rid="ref43">43</xref>,<xref ref-type="bibr" rid="ref45">45</xref>], moderate to vigorous PA [<xref ref-type="bibr" rid="ref32">32</xref>,<xref ref-type="bibr" rid="ref38">38</xref>,<xref ref-type="bibr" rid="ref40">40</xref>-<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref44">44</xref>], and walking [<xref ref-type="bibr" rid="ref29">29</xref>,<xref ref-type="bibr" rid="ref33">33</xref>,<xref ref-type="bibr" rid="ref34">34</xref>,<xref ref-type="bibr" rid="ref40">40</xref>-<xref ref-type="bibr" rid="ref42">42</xref>], assessed either directly (eg, with pedometer or activity tracker) or indirectly (eg, self-report measures such as the International Physical Activity Questionnaire [<xref ref-type="bibr" rid="ref33">33</xref>,<xref ref-type="bibr" rid="ref34">34</xref>,<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref45">45</xref>], Diabetes Self-Care Activities for assessment of PA [<xref ref-type="bibr" rid="ref37">37</xref>], Community Health Activities Model Program for Seniors PA [<xref ref-type="bibr" rid="ref42">42</xref>], Physical Activity Scale for the Elderly [<xref ref-type="bibr" rid="ref41">41</xref>], activity diary [<xref ref-type="bibr" rid="ref32">32</xref>], and Active Australia Survey [<xref ref-type="bibr" rid="ref43">43</xref>]). Studies were grouped by type of PA, and 4 meta-analyses were performed for daily step counts, total PA, moderate to vigorous PA, and walking (<xref rid="figure2" ref-type="fig">Figure 2</xref>).</p>
          <p>Compared with face-to-face interventions, interventions that included smart technology improved step count, with the meta-analysis of 11 studies and 738 participants demonstrating a MD of 1440 steps (95% CI 500-2390; <xref rid="figure2" ref-type="fig">Figure 2</xref>) [<xref ref-type="bibr" rid="ref27">27</xref>,<xref ref-type="bibr" rid="ref28">28</xref>,<xref ref-type="bibr" rid="ref30">30</xref>,<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref35">35</xref>,<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref38">38</xref>-<xref ref-type="bibr" rid="ref42">42</xref>]. Smart technology also improved total PA scores (8 studies, n=2069; SMD 0.17, 95% CI 0.17-0.52) and walking (4 studies, n=560; SMD 0.26, 95% CI 0.10-0.43) compared with face-to-face interventions. The meta-analysis of 3 studies (n=475) for moderate to vigorous PA was not statistically significant (SMD 0.04, 95% CI −0.14 to 0.22). We performed sensitivity analyses for all outcomes except moderate to vigorous PA. On the basis of the results of the risk of bias for the sensitivity analyses, we removed 5 studies with high risk of bias in the steps per day; however, the remaining 6 studies still favored smart technology with a MD of 2.03 (95% CI 0.35-3.71). Only 2 studies remained with 1388 participants for total PA; the difference was no longer significant with a SMD of 0.27 (95% CI −0.18 to 0.72). Finally, our sensitivity analysis for walking containing 2 studies (n=384) was not significant with a SMD of 0.22 (95% CI −0.04 to 0.48).</p>
          <fig id="figure2" position="float">
            <label>Figure 2</label>
            <caption>
              <p>Meta-analysis of effect of smart technology versus face-to-face alone on physical activity (PA).</p>
            </caption>
            <graphic xlink:href="jmir_v24i10e36134_fig2.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
          </fig>
        </sec>
        <sec>
          <title>Subgroup Analyses</title>
          <sec>
            <title>Smart Technology Components</title>
            <p>We completed meta-analyses for subgroups according to the type of smart technology that was used for steps per day and total PA scores (<xref ref-type="supplementary-material" rid="app1">Multimedia Appendix 1</xref>, section 5). Studies assessing steps per day used pedometers [<xref ref-type="bibr" rid="ref27">27</xref>,<xref ref-type="bibr" rid="ref30">30</xref>,<xref ref-type="bibr" rid="ref39">39</xref>,<xref ref-type="bibr" rid="ref40">40</xref>], smartphone apps [<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref41">41</xref>], telerehabilitation [<xref ref-type="bibr" rid="ref28">28</xref>,<xref ref-type="bibr" rid="ref42">42</xref>], and wearable activity trackers in their interventions [<xref ref-type="bibr" rid="ref35">35</xref>,<xref ref-type="bibr" rid="ref38">38</xref>]. When examining the effects of each intervention component separately, only smartphone apps (MD 3.07, 95% CI 0.5-5.55) and wearable activity trackers (MD 2.29, 95% CI 1.44-3.13) showed significant improvements in favor of smart technology interventions. Smart technology interventions for studies that assessed total PA included pedometers [<xref ref-type="bibr" rid="ref43">43</xref>], telerehabilitation [<xref ref-type="bibr" rid="ref42">42</xref>], websites [<xref ref-type="bibr" rid="ref45">45</xref>], smartphone apps [<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref41">41</xref>], and interventions including multiple smart technology components [<xref ref-type="bibr" rid="ref33">33</xref>,<xref ref-type="bibr" rid="ref34">34</xref>,<xref ref-type="bibr" rid="ref37">37</xref>]. In the subgroup meta-analyses, smartphone apps showed significant improvements in total PA scores compared with face-to-face alone (SMD 0.37, 95% CI 0.10-0.63), and multicomponent interventions favored smart technology, but the effect was not statistically significant (SMD 0.23, 95% CI −0.05 to 0.51).</p>
          </sec>
          <sec>
            <title>Smart Technology Alone</title>
            <p>There was a large variability in the components making up smart technology interventions in the included studies. Only 4 RCTs (n=1701) evaluated the effect of an entirely smart technology alone intervention (ie, did not include any in-person consultations) versus face-to-face alone [<xref ref-type="bibr" rid="ref28">28</xref>,<xref ref-type="bibr" rid="ref37">37</xref>,<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref45">45</xref>]. Subgroup analyses were performed for both steps per day and total PA scores. For both outcomes, the pooled results were not significant and did not appear to favor either intervention (<xref rid="figure2" ref-type="fig">Figure 2</xref>).</p>
            <p>The evidence for the effect of smart technology interventions on PA was judged to be very low based on the GRADE criteria (<xref rid="figure3" ref-type="fig">Figure 3</xref>). Therefore, our confidence in the effect estimate is limited, and the true effect is likely to be different from the estimated effect.</p>
            <fig id="figure3" position="float">
              <label>Figure 3</label>
              <caption>
                <p>Grading of Recommendations Assessment, Development, and Evaluation (GRADE) summary of findings table.</p>
              </caption>
              <graphic xlink:href="jmir_v24i10e36134_fig3.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
            </fig>
          </sec>
        </sec>
      </sec>
      <sec>
        <title>Physical Function</title>
        <sec>
          <title>Overview</title>
          <p>Of 19 studies, 10 (53%) evaluated some aspects of physical function. The most common performance-based measures were the 6-minute walk test (6-MWT) [<xref ref-type="bibr" rid="ref28">28</xref>-<xref ref-type="bibr" rid="ref30">30</xref>,<xref ref-type="bibr" rid="ref35">35</xref>,<xref ref-type="bibr" rid="ref41">41</xref>] and the 30-second sit-to-stand test [<xref ref-type="bibr" rid="ref27">27</xref>,<xref ref-type="bibr" rid="ref28">28</xref>,<xref ref-type="bibr" rid="ref39">39</xref>]. The remaining 13 measures were only included in 1 or 2 studies (eg, 4-meter gait speed [<xref ref-type="bibr" rid="ref34">34</xref>], short physical performance battery [<xref ref-type="bibr" rid="ref34">34</xref>], timed stair climbing [<xref ref-type="bibr" rid="ref35">35</xref>], peak VO<sub>2</sub> [<xref ref-type="bibr" rid="ref14">14</xref>,<xref ref-type="bibr" rid="ref39">39</xref>], hand grip strength [<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref34">34</xref>], maximal inspiratory and expiratory force [<xref ref-type="bibr" rid="ref29">29</xref>], and quadriceps force) [<xref ref-type="bibr" rid="ref29">29</xref>,<xref ref-type="bibr" rid="ref35">35</xref>] and therefore were not pooled (<xref rid="figure4" ref-type="fig">Figure 4</xref>). In total, 5 RCTs were pooled in a random effects meta-analysis for 6-MWT including 327 participants, with a MD of −1.77 m (95% CI −2.63 to −0.90) [<xref ref-type="bibr" rid="ref28">28</xref>,<xref ref-type="bibr" rid="ref29">29</xref>,<xref ref-type="bibr" rid="ref32">32</xref>,<xref ref-type="bibr" rid="ref34">34</xref>,<xref ref-type="bibr" rid="ref38">38</xref>]. Furthermore, 3 studies (n=184) that used the 30-second sit-to-stand test found no significant difference between interventions (SMD −0.37, 95% CI −1.66 to 0.92). The sensitivity analysis for the 6-MWT test included 3 studies (n=267). After removing those with a high risk of bias, the difference was not statistically significant (MD −3.26, 95% CI −19.97 to 13.45; <xref ref-type="supplementary-material" rid="app1">Multimedia Appendix 1</xref>).</p>
          <fig id="figure4" position="float">
            <label>Figure 4</label>
            <caption>
              <p>Meta-analysis of smart technology versus face-to-face alone for physical function. 6MWT- 6-minute walk test.</p>
            </caption>
            <graphic xlink:href="jmir_v24i10e36134_fig4.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
          </fig>
        </sec>
        <sec>
          <title>Subgroup Analyses</title>
          <sec>
            <title>Smart Technology Intervention Components</title>
            <p>We conducted additional meta-analyses on 5 studies that included the 6-MWT as an outcome by type of smart technology intervention component: pedometers [<xref ref-type="bibr" rid="ref29">29</xref>,<xref ref-type="bibr" rid="ref30">30</xref>], smartphone apps [<xref ref-type="bibr" rid="ref41">41</xref>], telerehabilitation [<xref ref-type="bibr" rid="ref28">28</xref>], and wearable activity trackers [<xref ref-type="bibr" rid="ref35">35</xref>]. We examined the effects of pedometer interventions on the 6-MWT on their own. There was a nonsignificant MD (4.40, 95% CI −25.28 to 34.07). Smart technology components included in the 3 studies with the 30-second sit-to-stand test were pedometers [<xref ref-type="bibr" rid="ref27">27</xref>,<xref ref-type="bibr" rid="ref39">39</xref>] and telerehabilitation [<xref ref-type="bibr" rid="ref28">28</xref>]. The findings were nonsignificant for pedometers compared with face-to-face alone with an MD of −0.60 (95% CI −2.14 to 0.94). Complete results for these meta-analyses are available in section 6 of <xref ref-type="supplementary-material" rid="app1">Multimedia Appendix 1</xref>.</p>
          </sec>
          <sec>
            <title>Smart Technology Alone</title>
            <p>Only 1 study (n=134) examined a smart technology intervention alone using telerehabilitation (video conferencing) [<xref ref-type="bibr" rid="ref28">28</xref>]. For both the 6-MWT and the 30-second sit-to-stand test, results in this study favored the face-to-face intervention.</p>
            <p>The evidence for the effect of smart technology on the 6-MWT and the 30-second sit-to-stand test was judged to be very low based on the GRADE criteria. Therefore, our confidence in the effect estimates is limited, and the true effect may be substantially different from the estimated effect.</p>
          </sec>
        </sec>
      </sec>
      <sec>
        <title>Adherence Rates</title>
        <p>A total of 10 studies did not report adherence rates [<xref ref-type="bibr" rid="ref30">30</xref>,<xref ref-type="bibr" rid="ref32">32</xref>-<xref ref-type="bibr" rid="ref34">34</xref>,<xref ref-type="bibr" rid="ref37">37</xref>,<xref ref-type="bibr" rid="ref38">38</xref>,<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref43">43</xref>,<xref ref-type="bibr" rid="ref45">45</xref>]. Two studies reported overall adherence to the intervention [<xref ref-type="bibr" rid="ref28">28</xref>,<xref ref-type="bibr" rid="ref42">42</xref>], and 7 studies reported adherence to the components of the intervention [<xref ref-type="bibr" rid="ref27">27</xref>,<xref ref-type="bibr" rid="ref29">29</xref>,<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref35">35</xref>,<xref ref-type="bibr" rid="ref39">39</xref>,<xref ref-type="bibr" rid="ref41">41</xref>,<xref ref-type="bibr" rid="ref44">44</xref>]. Overall, across the available studies, adherence rates to smart technology interventions ranged from 64.8% [<xref ref-type="bibr" rid="ref42">42</xref>] to 95.5% [<xref ref-type="bibr" rid="ref27">27</xref>]. Adherence to specific smart technology interventions was reported as follows: pedometers ranged from 76% [<xref ref-type="bibr" rid="ref39">39</xref>] to 95.5% [<xref ref-type="bibr" rid="ref27">27</xref>], and telerehabilitation ranged from 64.8% [<xref ref-type="bibr" rid="ref32">32</xref>] to 85% [<xref ref-type="bibr" rid="ref28">28</xref>]. The adherence to face-to-face interventions ranged from 64% [<xref ref-type="bibr" rid="ref28">28</xref>] to 100% [<xref ref-type="bibr" rid="ref41">41</xref>].</p>
      </sec>
      <sec>
        <title>Secondary Outcomes</title>
        <p>Three studies measured depression using different scales, including the Hospital Anxiety and Depression Scale [<xref ref-type="bibr" rid="ref28">28</xref>], Beck Depression Inventory [<xref ref-type="bibr" rid="ref27">27</xref>], and Care Depression Instrument [<xref ref-type="bibr" rid="ref37">37</xref>]. We pooled data from 2 RCTs for a random effects meta-analysis, which showed no significant difference between interventions that included smart technology and face-to-face alone (SMD 0.09, 95% CI −0.23 to 0.41) [<xref ref-type="bibr" rid="ref27">27</xref>,<xref ref-type="bibr" rid="ref28">28</xref>]. Furthermore, 6 studies measured HRQoL using the Clinical COPD Questionnaire [<xref ref-type="bibr" rid="ref28">28</xref>,<xref ref-type="bibr" rid="ref31">31</xref>], St George’s Respiratory Questionnaire [<xref ref-type="bibr" rid="ref27">27</xref>,<xref ref-type="bibr" rid="ref30">30</xref>], HeartQoL global score [<xref ref-type="bibr" rid="ref33">33</xref>], and Chronic Respiratory Disease Questionnaire [<xref ref-type="bibr" rid="ref29">29</xref>]. A meta-analysis of 6 studies demonstrated a significant SMD (0.31, 95% CI 0.11-0.51) in favor of smart technology interventions. For HRQoL, we completed a subgroup analysis by smart technology component; multicomponent interventions (n=2; SMD 0.35, 95% CI 0.05-0.66) showed significant improvements compared with face-to-face alone, but pedometers did not (n=3; SMD 0.04, 95% CI −0.49 to 0.57). After performing a sensitivity analysis excluding studies with a high risk of bias, our results did not change the significance or direction of results. Only 1 study examined anxiety using the Hospital Anxiety and Depression Scale and demonstrated an improvement in favor of smart technology at the first follow-up [<xref ref-type="bibr" rid="ref28">28</xref>]. Meta-analyses for secondary outcomes are available in <xref ref-type="supplementary-material" rid="app1">Multimedia Appendix 1</xref>.</p>
      </sec>
    </sec>
    <sec sec-type="discussion">
      <title>Discussion</title>
      <sec>
        <title>Principal Findings</title>
        <p>PA is integral to reducing age-related illness and disability. This review of 19 studies involving 3455 patients found that interventions that include smart technology may improve steps per day, total PA, walking, and HRQoL in older adults. Although the overall quality and certainty of the evidence were judged to be very low and more precise estimates will need to be obtained, our results may have important implications for research and practice on PA promotion, especially in the context of the COVID-19 pandemic and public health restrictions.</p>
        <p>Among the included studies, we found that most (n=15) smart technology interventions used multiple components with intervention groups also receiving a face-to-face component. One of the challenges of multicomponent interventions is that it limits our understanding of the effectiveness of smart technology alone. For example, intervention and control groups in several studies received usual care, with the only difference between groups being the addition of a pedometer or wearable activity tracker [<xref ref-type="bibr" rid="ref29">29</xref>,<xref ref-type="bibr" rid="ref38">38</xref>-<xref ref-type="bibr" rid="ref40">40</xref>]. Of the 4 studies examining smart technology alone, 2 examined the effect on steps per day; our subgroup analysis found a nonsignificant difference of 260 steps per day favoring smart technology [<xref ref-type="bibr" rid="ref28">28</xref>,<xref ref-type="bibr" rid="ref42">42</xref>]. Notably, the results from these 2 studies were contradictory, with Hansen et al [<xref ref-type="bibr" rid="ref28">28</xref>] reporting that face-to-face interventions were more effective. However, they evaluated patients with severe COPD and reported a decline in PA for both groups over the course of the study. This may be caused, in part, by the progressive nature of COPD or by the short length of the intervention at only 10 weeks [<xref ref-type="bibr" rid="ref28">28</xref>]. In line with our meta-analysis for steps per day, the 3 RCTs examining the effect of smart technology alone on total PA showed a small, nonsignificant effect favoring smart technology [<xref ref-type="bibr" rid="ref37">37</xref>,<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref45">45</xref>]. It will be important for future work to determine whether smart technology on its own is more, less, or as effective as face-to-face interventions. This is especially important during the COVID-19 pandemic, as in-person contacts should be limited to minimize the risk of transmission. Conversely, if smart technology interventions alone are less effective, it will be important to revert to including some type of face-to-face component as soon as it is safe and feasible.</p>
        <p>Patient-important outcomes were not well represented in our included studies, which highlights an important gap in the design and reporting of smart technology interventions. Among 19 studies, only 7 (37%) unique studies reported on patient-important outcomes: 6 reported on HRQoL [<xref ref-type="bibr" rid="ref27">27</xref>-<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref33">33</xref>], 3 on depression [<xref ref-type="bibr" rid="ref27">27</xref>,<xref ref-type="bibr" rid="ref28">28</xref>,<xref ref-type="bibr" rid="ref37">37</xref>], and 1 on anxiety [<xref ref-type="bibr" rid="ref28">28</xref>]. Evidence has demonstrated associations between PA levels and mental health and quality of life in older adults [<xref ref-type="bibr" rid="ref51">51</xref>]. Therefore, it is vital that research includes these measures to further our understanding of the magnitude and direction of these relationships. This is timely as we have seen the prevalence of depression and anxiety increasing over the last 2 years with the pandemic and public health restrictions [<xref ref-type="bibr" rid="ref52">52</xref>]. Older adults have been shown to be at an increased risk for anxiety [<xref ref-type="bibr" rid="ref52">52</xref>]. In addition to the lack of patient-important outcomes, we found that data on intervention adherence were largely missing or inconsistently reported. This leads to several challenges, including understanding the acceptability of these interventions for older adults and interpreting results of the primary studies. For example, if adherence to the intervention was poor, it would be difficult to appreciate if the differences (or lack thereof) between groups were because of intervention failure or implementation failure. The issue of acceptability is also crucial, particularly considering that the current literature on the usability of technology in this population is limited.</p>
        <p>Our results suggest that the type of smart technology used for PA interventions may influence the effectiveness of the intervention. We found that studies that used smartphone apps led to significant improvements in steps per day and total PA scores [<xref ref-type="bibr" rid="ref53">53</xref>]. Other systematic reviews examining the effectiveness of mobile phone interventions in adults aged &#62;18 years and &#62;50 years and older adults (&#62;65 years) have shown mixed evidence for improving PA [<xref ref-type="bibr" rid="ref53">53</xref>-<xref ref-type="bibr" rid="ref55">55</xref>]. Potential reasons for these discordant results may be the diversity of interventions within control groups, small sample sizes, and moderate to high levels of heterogeneity across studies [<xref ref-type="bibr" rid="ref53">53</xref>,<xref ref-type="bibr" rid="ref54">54</xref>]. We also found that wearable activity trackers significantly improved the number of steps per day. Researchers should consider the type of smart technology in conjunction with the PA goals and the population to achieve the best outcome. Further research is warranted to determine the optimal types of smart technology interventions for older adults.</p>
        <p>The existing literature has several limitations that warrant future research. Our findings are based on very low quality of evidence, as per the GRADE criteria. All included studies had some concerns or a high risk of bias, most commonly because of missingness of outcomes, lack of intention-to-treat analyses, inadequate allocation concealment, and lack of prespecified statistical analyses or protocols. The variability in populations, smart technology interventions, control group interventions, and outcomes among studies are major contributing factors to the large degree of statistical heterogeneity. Furthermore, most studies used multiple components, making it difficult to assess which parts may have contributed to differences between groups or, conversely, if additive components may have diluted a potentially effective intervention. Importantly, 79% (15/19) of the studies included an element of face-to-face interaction in the intervention group, making it difficult to evaluate the effectiveness of smart technology alone. Due to the limited number of studies and small sample sizes, there is a need to group studies and smart technologies broadly to have sufficient sample sizes to conduct meta-analyses. Given that different smart technologies can be used for different intervention components, it may be difficult to apply our findings in practice when designing interventions. Although we conducted subgroup analyses where there were sufficient data, there is a need for additional research comparing different types of smart technologies for supporting specific PA interventions in older adults [<xref ref-type="bibr" rid="ref18">18</xref>,<xref ref-type="bibr" rid="ref19">19</xref>,<xref ref-type="bibr" rid="ref23">23</xref>]. Finally, our results may have been influenced by the high risk of performance bias caused by the impracticability of blinding therapists and participants owing to the nature of the interventions. Future research should focus on minimizing the risk of bias, evaluating individual smart technology components and smart technology alone, and including standardized control groups. Improved reporting of control group interventions may also assist with interpretation of results.</p>
        <p>This review also has some limitations. We did not include gray literature owing to a lack of central sources to identify and retrieve these citations [<xref ref-type="bibr" rid="ref56">56</xref>]. In addition, we excluded studies published in languages other than English because of the feasibility of the review. Therefore, our cohort of studies may not represent the entirety of the literature. This review has several important strengths. To the best of our knowledge, this is the first study to attempt to compare smart technology interventions specifically with face-to-face interventions, which is critical for determining their effectiveness compared with traditional modes of delivery. In addition, we published our peer-reviewed protocol, and we developed and conducted our search in collaboration with a health research librarian.</p>
      </sec>
      <sec>
        <title>Conclusions</title>
        <p>In the context of substantial heterogeneity and very low quality of evidence, our results suggest that PA interventions that include smart technology components may significantly improve steps per day and total PA in community-dwelling older adults. Subgroup analyses showed that smartphone apps and wearable activity trackers seem to be the most effective smart technology, which may be helpful for health care practitioners when determining appropriate methods of remote PA promotion. When comparing smart technology alone with face-to-face alone, there were few studies with discordant results and no significant differences between groups. The results should be interpreted with caution given the challenges with the existing literature cited in the discussion.</p>
      </sec>
    </sec>
  </body>
  <back>
    <app-group>
      <supplementary-material id="app1">
        <label>Multimedia Appendix 1</label>
        <p>Description of data: search strategies, full text exclusion reasons, detailed intervention reasons, risk of bias summary, physical activity meta-analyses, and secondary outcome meta-analyses.</p>
        <media xlink:href="jmir_v24i10e36134_app1.doc" xlink:title="DOC File , 6397 KB"/>
      </supplementary-material>
    </app-group>
    <glossary>
      <title>Abbreviations</title>
      <def-list>
        <def-item>
          <term id="abb1">COPD</term>
          <def>
            <p>chronic obstructive pulmonary disease</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb2">GRADE</term>
          <def>
            <p>Grading of Recommendations Assessment, Development, and Evaluation</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb3">HRQoL</term>
          <def>
            <p>health-related quality of life</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb4">MD</term>
          <def>
            <p>mean difference</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb5">PA</term>
          <def>
            <p>physical activity</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb6">PRISMA</term>
          <def>
            <p>Preferred Reporting Items for Systematic Reviews and Meta-Analysis</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb7">RCT</term>
          <def>
            <p>randomized controlled trial</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb8">SMD</term>
          <def>
            <p>standardized mean difference</p>
          </def>
        </def-item>
      </def-list>
    </glossary>
    <ack>
      <p>JCR was funded by the Canadian Frailty Network Interdisciplinary Fellowship and MKB holds a Tier 2 Canada Research Chair in Mobility, Aging and Chronic Disease.</p>
    </ack>
    <fn-group>
      <fn fn-type="conflict">
        <p>None declared.</p>
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