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<article xmlns:xlink="http://www.w3.org/1999/xlink" article-type="research-article" dtd-version="2.0">
  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JMIR</journal-id>
      <journal-id journal-id-type="nlm-ta">J Med Internet Res</journal-id>
      <journal-title>Journal of Medical Internet Research</journal-title>
      <issn pub-type="epub">1438-8871</issn>
      <publisher>
        <publisher-name>JMIR Publications</publisher-name>
        <publisher-loc>Toronto, Canada</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">v24i1e20466</article-id>
      <article-id pub-id-type="pmid">34982040</article-id>
      <article-id pub-id-type="doi">10.2196/20466</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Original Paper</subject>
        </subj-group>
        <subj-group subj-group-type="article-type">
          <subject>Original Paper</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>The Contribution of the Internet to Reducing Social Isolation in Individuals Aged 50 Years and Older: Quantitative Study of Data From the Survey of Health, Ageing and Retirement in Europe</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="editor">
          <name>
            <surname>Kukafka</surname>
            <given-names>Rita</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Stuart</surname>
            <given-names>Avelie</given-names>
          </name>
        </contrib>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Wieringa</surname>
            <given-names>Thomas</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib id="contrib1" contrib-type="author" corresp="yes" equal-contrib="yes">
          <name name-style="western">
            <surname>Silva</surname>
            <given-names>Patrícia</given-names>
          </name>
          <degrees>PhD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <address>
            <institution>Communication and Society Research Centre</institution>
            <institution>University of Minho</institution>
            <addr-line>Campus Gualtar, Social Sciences Institute</addr-line>
            <addr-line>Braga, 4710-057</addr-line>
            <country>Portugal</country>
            <phone>351 253604212</phone>
            <email>patriciasilva@ics.uminho.pt</email>
          </address>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0003-4074-5368</ext-link>
        </contrib>
        <contrib id="contrib2" contrib-type="author" equal-contrib="yes">
          <name name-style="western">
            <surname>Delerue Matos</surname>
            <given-names>Alice</given-names>
          </name>
          <degrees>PhD</degrees>
          <xref rid="aff2" ref-type="aff">2</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-2394-4077</ext-link>
        </contrib>
        <contrib id="contrib3" contrib-type="author" equal-contrib="yes">
          <name name-style="western">
            <surname>Martinez-Pecino</surname>
            <given-names>Roberto</given-names>
          </name>
          <degrees>PhD</degrees>
          <xref rid="aff3" ref-type="aff">3</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0003-0765-1407</ext-link>
        </contrib>
      </contrib-group>
      <aff id="aff1">
        <label>1</label>
        <institution>Communication and Society Research Centre</institution>
        <institution>University of Minho</institution>
        <addr-line>Braga</addr-line>
        <country>Portugal</country>
      </aff>
      <aff id="aff2">
        <label>2</label>
        <institution>Department of Sociology, Institute of Social Sciences</institution>
        <institution>University of Minho</institution>
        <addr-line>Braga</addr-line>
        <country>Portugal</country>
      </aff>
      <aff id="aff3">
        <label>3</label>
        <institution>Departamento de Psicología Social, Facultad de Comunicación</institution>
        <institution>Universidad Sevilla</institution>
        <addr-line>Seville</addr-line>
        <country>Spain</country>
      </aff>
      <author-notes>
        <corresp>Corresponding Author: Patrícia Silva <email>patriciasilva@ics.uminho.pt</email></corresp>
      </author-notes>
      <pub-date pub-type="collection">
        <month>1</month>
        <year>2022</year>
      </pub-date>
      <pub-date pub-type="epub">
        <day>3</day>
        <month>1</month>
        <year>2022</year>
      </pub-date>
      <volume>24</volume>
      <issue>1</issue>
      <elocation-id>e20466</elocation-id>
      <history>
        <date date-type="received">
          <day>20</day>
          <month>5</month>
          <year>2020</year>
        </date>
        <date date-type="rev-request">
          <day>27</day>
          <month>10</month>
          <year>2020</year>
        </date>
        <date date-type="rev-recd">
          <day>3</day>
          <month>12</month>
          <year>2020</year>
        </date>
        <date date-type="accepted">
          <day>23</day>
          <month>9</month>
          <year>2021</year>
        </date>
      </history>
      <copyright-statement>©Patrícia Silva, Alice Delerue Matos, Roberto Martinez-Pecino. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 03.01.2022.</copyright-statement>
      <copyright-year>2022</copyright-year>
      <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
        <p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Journal of Medical Internet Research, is properly cited. The complete bibliographic information, a link to the original publication on https://www.jmir.org/, as well as this copyright and license information must be included.</p>
      </license>
      <self-uri xlink:href="https://www.jmir.org/2022/1/e20466" xlink:type="simple"/>
      <abstract>
        <sec sec-type="background">
          <title>Background</title>
          <p>Social isolation has a negative impact on the quality of life of older people; therefore, studies have focused on identifying its sociodemographic, economic, and health determinants. In view of the growing importance of the internet as a means of communication, it is essential to assess whether internet use interferes with social isolation.</p>
        </sec>
        <sec sec-type="objective">
          <title>Objective</title>
          <p>This study specifically aims to clarify the relationship between internet use and social isolation of individuals aged ≥50 years, for which other surveys present contradictory results.</p>
        </sec>
        <sec sec-type="methods">
          <title>Methods</title>
          <p>We performed logistic regression analysis with social isolation as the dependent variable, internet use as the interest variable, and several other sociodemographic, economic, and health characteristics of the individuals as control variables. The sample size was 67,173 individuals aged 50 years and older from 17 European countries (Portugal, Greece, Italy, Spain, Denmark, Sweden, Austria, Belgium, France, Germany, Switzerland, Luxemburg, Poland, Czech Republic, Slovenia, Estonia, and Croatia) plus Israel, who were interviewed in the Survey of Health, Ageing and Retirement in Europe (SHARE), wave 6.</p>
        </sec>
        <sec sec-type="results">
          <title>Results</title>
          <p>The results show that countries differ in the level of social isolation and rate of internet use by individuals aged 50 years and older. They also evidence that in most of the countries analyzed, social isolation of internet users was lower compared to that of nonusers after controlling for a set of sociodemographic, economic, and health characteristics of the individuals that have been previously described in the literature as determinants of social isolation. Indeed, on average, although 31.4% of individuals in the nonuser group experienced high social isolation, only 12.9% of individuals who used the internet experienced this condition.</p>
        </sec>
        <sec sec-type="conclusions">
          <title>Conclusions</title>
          <p>Internet users show lower social isolation. This result underlines the importance of promoting e-inclusion in Europe as a way to counter social isolation of individuals aged 50 years and older.</p>
        </sec>
      </abstract>
      <kwd-group>
        <kwd>social isolation</kwd>
        <kwd>internet</kwd>
        <kwd>50+ individuals</kwd>
        <kwd>e-inclusion</kwd>
        <kwd>SHARE</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec sec-type="introduction">
      <title>Introduction</title>
      <p>Social isolation has been defined as the objective situation of individuals with small social networks and reduced frequency of contact who do not take part in social activities [<xref ref-type="bibr" rid="ref1">1</xref>-<xref ref-type="bibr" rid="ref4">4</xref>]. According to the literature, social isolation is associated with an increased risk of mortality [<xref ref-type="bibr" rid="ref2">2</xref>,<xref ref-type="bibr" rid="ref5">5</xref>-<xref ref-type="bibr" rid="ref7">7</xref>]. In terms of health, it has been associated with a greater risk of developing chronic diseases [<xref ref-type="bibr" rid="ref8">8</xref>] and cardiovascular disease [<xref ref-type="bibr" rid="ref3">3</xref>,<xref ref-type="bibr" rid="ref7">7</xref>], as well as increased risk of physical inactivity, tobacco consumption, and various other risk behaviors [<xref ref-type="bibr" rid="ref3">3</xref>,<xref ref-type="bibr" rid="ref9">9</xref>]. Furthermore, in old age, social isolation is associated with increased feelings of loneliness [<xref ref-type="bibr" rid="ref3">3</xref>].</p>
      <p>According to the literature, social isolation tends to increase as individuals age [<xref ref-type="bibr" rid="ref3">3</xref>,<xref ref-type="bibr" rid="ref10">10</xref>,<xref ref-type="bibr" rid="ref11">11</xref>]. Indeed, some events that are more frequent at an older age, such as retirement, the development or worsening of health and mobility limitations, or a change in residence of the individuals with whom they socialize [<xref ref-type="bibr" rid="ref2">2</xref>,<xref ref-type="bibr" rid="ref12">12</xref>-<xref ref-type="bibr" rid="ref16">16</xref>], tend to affect older people’s ability to maintain their social networks and may also cause cognitive decline [<xref ref-type="bibr" rid="ref17">17</xref>] and increase social isolation [<xref ref-type="bibr" rid="ref2">2</xref>].</p>
      <p>Social isolation is determined by a set of sociodemographic, economic, and health characteristics of individuals [<xref ref-type="bibr" rid="ref3">3</xref>,<xref ref-type="bibr" rid="ref10">10</xref>,<xref ref-type="bibr" rid="ref13">13</xref>,<xref ref-type="bibr" rid="ref18">18</xref>,<xref ref-type="bibr" rid="ref19">19</xref>]. In addition to these determinants, the role of the internet in reducing social isolation is increasingly being discussed [<xref ref-type="bibr" rid="ref20">20</xref>] because, as an important means of communication, this technology can facilitate interpersonal contact at a stage of life when social networks tend to be restructured [<xref ref-type="bibr" rid="ref12">12</xref>,<xref ref-type="bibr" rid="ref21">21</xref>-<xref ref-type="bibr" rid="ref24">24</xref>]. There are often obstacles to the use of the internet by people of advanced age [<xref ref-type="bibr" rid="ref25">25</xref>-<xref ref-type="bibr" rid="ref31">31</xref>]. However, internet use by older adults has been associated with feelings of well-being and social support [<xref ref-type="bibr" rid="ref32">32</xref>-<xref ref-type="bibr" rid="ref35">35</xref>], as well as with improved quality of life [<xref ref-type="bibr" rid="ref36">36</xref>]. Nevertheless, the relationship between internet use and social isolation is unclear, and there is open debate in the literature. On the one hand, some studies conclude that internet use is associated with a decrease in social isolation [<xref ref-type="bibr" rid="ref11">11</xref>,<xref ref-type="bibr" rid="ref20">20</xref>,<xref ref-type="bibr" rid="ref37">37</xref>,<xref ref-type="bibr" rid="ref38">38</xref>]. In this regard, they claim that the internet has been conducive to successful interactions [<xref ref-type="bibr" rid="ref39">39</xref>-<xref ref-type="bibr" rid="ref41">41</xref>] and contributes to maintaining social ties [<xref ref-type="bibr" rid="ref41">41</xref>-<xref ref-type="bibr" rid="ref44">44</xref>] and increasing the frequency of contact [<xref ref-type="bibr" rid="ref45">45</xref>], as well as optimizing the effect of social networks on the quality of life of older people [<xref ref-type="bibr" rid="ref36">36</xref>]. On the other hand, other studies conclude that using this technology does not reduce social isolation [<xref ref-type="bibr" rid="ref46">46</xref>]. Furthermore, in some specific cases, its use is actually associated with a greater risk of social isolation. In this regard, problematic and addictive uses of the internet may be related to social isolation [<xref ref-type="bibr" rid="ref47">47</xref>]. Similarly, some studies support the “time displacement” thesis, which states that the longer individuals surf the internet, the less time they interact with family and friends, as the time spent on one activity cannot be spent on another [<xref ref-type="bibr" rid="ref48">48</xref>].</p>
      <p>The inconsistent results in the literature underscore the need for more research into the relationship between internet use and social isolation [<xref ref-type="bibr" rid="ref20">20</xref>,<xref ref-type="bibr" rid="ref49">49</xref>], in which this concept is clearly defined [<xref ref-type="bibr" rid="ref50">50</xref>] and which draws on large samples [<xref ref-type="bibr" rid="ref38">38</xref>,<xref ref-type="bibr" rid="ref51">51</xref>]. This study specifically aims to contribute to this goal by focusing on the relationship between internet use and social isolation after controlling for sociodemographic, economic, and health variables and selecting a target population of individuals aged 50 years or older residing in 17 European countries and Israel.</p>
    </sec>
    <sec sec-type="methods">
      <title>Methods</title>
      <sec>
        <title>Data and Sample</title>
        <p>This study focuses on 67,173 individuals aged 50 years and older who were interviewed in the Survey of Health, Ageing and Retirement in Europe (SHARE) Project (wave 6) in Austria (n=3358), Germany (n=4347), Sweden (n=3881), Spain (n=5560), Italy (n=5211), France (n=3870), Denmark (n=3661), Greece (n=4814), Switzerland (n=2772), Belgium (n=5700), Israel (n=2013), Czech Republic (n=4793), Poland (n=1802), Luxembourg (n=1543), Portugal (n=1662), Slovenia (n=4186), Estonia (n=5557), and Croatia (n=2443). Details of the SHARE study in Europe have been described elsewhere [<xref ref-type="bibr" rid="ref52">52</xref>]. Briefly, in wave 6 (2015), a survey of a representative sample of the noninstitutionalized population aged 50 years or older was conducted. Interviews were face-to-face and took place in the household. Trained interviewers conducted the interviews using a computer-assisted personal interviewing program.</p>
        <p>The SHARE project, coordinated internationally by the Max Planck Institute for Social Law and Social Policy (Germany), has been approved by the Ethics Council of the Max Planck Society for the Advancement of Science.</p>
      </sec>
      <sec>
        <title>Measures</title>
        <sec>
          <title>Dependent Variable: Social Isolation</title>
          <p>As in other research [<xref ref-type="bibr" rid="ref3">3</xref>,<xref ref-type="bibr" rid="ref4">4</xref>,<xref ref-type="bibr" rid="ref53">53</xref>], social isolation was computed using a 5-item index. Individuals scored 1 point if they did not live with a partner; 1 point if they did not belong to any organizations, clubs, or religious groups; and 1 point for having less than monthly contact with friends, family, or children. Scores on the index ranged from 0 to 5, with higher scores indicating a greater degree of isolation. Adopting the criteria of previous studies [<xref ref-type="bibr" rid="ref2">2</xref>,<xref ref-type="bibr" rid="ref54">54</xref>-<xref ref-type="bibr" rid="ref56">56</xref>], we dichotomized the social isolation index to distinguish between low (score &#60;2) and high (score ≥2) levels of social isolation.</p>
          <p>Low social isolation was coded as 0, and high social isolation was coded as 1.</p>
        </sec>
        <sec>
          <title>Independent Variable: Internet Use</title>
          <p>This is a dichotomous variable relating to use of the internet at least once in the last 7 days to send and receive emails, to search for information, to shop, or for any other purpose. This variable distinguishes individuals who use the internet (1) from individuals who do not use it (0).</p>
        </sec>
        <sec>
          <title>Covariables: Sociodemographic and Economic Variables</title>
          <p>The following covariables were considered in this research:</p>
          <list list-type="bullet">
            <list-item>
              <p>Age; gender: female (1) and male (0); years of schooling; self-perception of financial stress: “great difficulty” or “some difficulty” in coping with monthly expenses (0), “easy” or “very easy” to cover monthly expenses (1).</p>
            </list-item>
            <list-item>
              <p>Geographical distance from social network: scores ranged from ”in the same household” (1) to “more than 500 km away” (8).</p>
            </list-item>
            <list-item>
              <p>Loneliness: assessed through a short version of the Revised UCLA Loneliness Scale (R-UCLA) [<xref ref-type="bibr" rid="ref57">57</xref>]. The scale includes 3 questions: “How much of the time do you feel you lack companionship?” “How much of the time do you feel left out?” and “How much of the time do you feel isolated from others?” The answer options range from 1 (hardly ever) to 3 (often). The 3 items form a scale that ranges from 3 to 9 points, in which high values represent higher levels of loneliness.</p>
            </list-item>
          </list>
          <p>We also considered health variables:</p>
          <list list-type="bullet">
            <list-item>
              <p>Depressive symptoms, evaluated by the EURO-D scale [<xref ref-type="bibr" rid="ref58">58</xref>]. The EURO-D scale ranges from 0 to 12 points, which refer to the presence or absence of 12 symptoms of depression, such as suicidal thoughts [<xref ref-type="bibr" rid="ref58">58</xref>]; as in previous studies [<xref ref-type="bibr" rid="ref59">59</xref>], we distinguished between more symptoms (1) and individuals with lower scores (0). A score of 4 or more symptoms is considered as a cutoff point to identify major depression [<xref ref-type="bibr" rid="ref60">60</xref>].</p>
            </list-item>
            <list-item>
              <p>Limitations in activities of daily living [<xref ref-type="bibr" rid="ref61">61</xref>,<xref ref-type="bibr" rid="ref62">62</xref>], which refer to the presence-absence of difficulties performing on one’s own any of 6 daily living activities, such as bathing, dressing, and toileting; we distinguished between individuals who reported 1 or more limitations (1) and individuals who reported no limitations (0).</p>
            </list-item>
            <list-item>
              <p>Physical inactivity: Two items were used to assess the level of physical activity. The first item assessed vigorous physical activity (“We would like to know about the type and amount of physical activity you do in your daily life. How often do you engage in vigorous physical activity, such as sports, heavy housework, or a job that involves physical labor?”). The second item assessed moderate physical activity (“How often do you engage in activities that require a low or moderate level of energy such as gardening, cleaning the car, or doing a walk?”). Participants answered both items by using a 4-point rating scale (1, more than once a week; 2, once a week; 3, 1 to 3 times a month; 4, hardly ever or never). Participants who did not perform any of these activities (never engaged in vigorous or moderate physical activity) were classified as “physically inactive” (1), and individuals who performed at least one vigorous or moderate physical activity were classified as “physically active” (0).</p>
            </list-item>
          </list>
        </sec>
      </sec>
      <sec>
        <title>Statistical Analysis</title>
        <p>Given that the SHARE project includes national samples from different countries and the sample design is not uniform among them, calibrated individual weights were used in the descriptive statistical analysis (for further details, see [<xref ref-type="bibr" rid="ref63">63</xref>,<xref ref-type="bibr" rid="ref64">64</xref>]). To compare sociodemographic, economic, and health characteristics between individuals who experience high levels of social isolation and individuals with low levels of social isolation, the chi-square test and Student <italic>t</italic> test were performed. We used the chi-square test to assess the interdependence between two nominal variables (eg, differences between gender according to their degree of social isolation). The sample means were also compared using Student <italic>t</italic> tests for independent samples (eg, differences in mean age according to their degree of social isolation). Statistical test results with <italic>P</italic>&#60;.05 were considered to be significant. The results from these tests were complemented with effect size measures (Cohen <italic>d</italic>/<italic>φ</italic>). The interpretation of the results was based on Cohen [<xref ref-type="bibr" rid="ref65">65</xref>].</p>
        <p>To analyze the relationship between internet use and social isolation, logistic regressions were conducted by country using the Enter method (in which all the dependent variables are inserted in the statistical model simultaneously). The logistic regression is a mathematical model that give odds ratios (ORs) that are adjusted for other covariates (including confounders) [<xref ref-type="bibr" rid="ref66">66</xref>]. Thus, 18 separate analyses were performed (1 for each country). Weights were not used in the logistic regressions. These analyses were performed using SPSS software (version 25; IBM Corp).</p>
      </sec>
    </sec>
    <sec sec-type="results">
      <title>Results</title>
      <p>Eastern and Southern Europe are the opposite of Northern and Central Europe in terms of social isolation (<xref ref-type="table" rid="table1">Table 1</xref>). In fact, the percentage of individuals aged 50 years and older who are socially isolated is higher in Eastern and Southern Europe (with the exception of Portugal) compared to the two other European regions. An analysis by country confirmed that the highest weighted percentage of people who experience a high level of social isolation is found in Poland (n=463; 36.8%), and the lowest is found in Denmark (n=321; 11.8%).</p>
      <p>With regard to internet use, the countries of Northern and Central Europe also stand out in terms of recording the highest percentages of users, with Denmark once again showing the highest rate of use of technology (n=3053; 81.9%). In contrast, the countries of Eastern and Southern Europe have the lowest rates of internet use, with Croatia standing out as a country where fewer individuals use the internet (n=715; 27.2%).</p>
      <p>In all the countries analyzed, high levels of social isolation are clearly more common among individuals who do not use the internet as compared to those using this technology (<xref rid="figure1" ref-type="fig">Figure 1</xref>). Indeed, while on average, in the group of internet users, only 12.9% experience high levels of social isolation, in the group of nonusers, 31.4% are in this situation.</p>
      <table-wrap position="float" id="table1">
        <label>Table 1</label>
        <caption>
          <p>Individuals in the high isolation group (n=11,614) and internet users (n=32,399) by country (N unweighted). Source: Survey of Health, Ageing and Retirement in Europe wave 6, version 7.0.0; weighted data.</p>
        </caption>
        <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
          <col width="250"/>
          <col width="420"/>
          <col width="330"/>
          <thead>
            <tr valign="top">
              <td>Country</td>
              <td>High social isolation group, n (%)</td>
              <td>Internet users, n (%)</td>
            </tr>
          </thead>
          <tbody>
            <tr valign="top">
              <td>Poland</td>
              <td>463 (36.8)</td>
              <td>447 (28.1)</td>
            </tr>
            <tr valign="top">
              <td>Estonia</td>
              <td>1408 (33.0)</td>
              <td>2490 (47.6)</td>
            </tr>
            <tr valign="top">
              <td>Croatia</td>
              <td>486 (31.2)</td>
              <td>715 (27.2)</td>
            </tr>
            <tr valign="top">
              <td>Italy</td>
              <td>914 (26.6)</td>
              <td>1698 (33.6)</td>
            </tr>
            <tr valign="top">
              <td>Slovenia</td>
              <td>726 (24.5)</td>
              <td>1564 (40.9)</td>
            </tr>
            <tr valign="top">
              <td>Greece</td>
              <td>1010 (23.3)</td>
              <td>1265 (27.9)</td>
            </tr>
            <tr valign="top">
              <td>Spain</td>
              <td>946 (22.6)</td>
              <td>1655 (37.5)</td>
            </tr>
            <tr valign="top">
              <td>Czech Republic</td>
              <td>1028 (21.2)</td>
              <td>2268 (50.9)</td>
            </tr>
            <tr valign="top">
              <td>Israel</td>
              <td>307 (20.0)</td>
              <td>949 (50.0)</td>
            </tr>
            <tr valign="top">
              <td>Germany</td>
              <td>552 (19.8)</td>
              <td>2592 (57.6)</td>
            </tr>
            <tr valign="top">
              <td>Austria</td>
              <td>602 (18.8)</td>
              <td>1606 (52.6)</td>
            </tr>
            <tr valign="top">
              <td>France</td>
              <td>739 (18.8)</td>
              <td>2178 (59.8)</td>
            </tr>
            <tr valign="top">
              <td>Luxembourg</td>
              <td>184 (18.0)</td>
              <td>955 (59.6)</td>
            </tr>
            <tr valign="top">
              <td>Switzerland</td>
              <td>395 (17.2)</td>
              <td>1912 (71.4)</td>
            </tr>
            <tr valign="top">
              <td>Portugal</td>
              <td>231 (16.9)</td>
              <td>451 (30.8)</td>
            </tr>
            <tr valign="top">
              <td>Belgium</td>
              <td>891 (15.8)</td>
              <td>3684 (65.1)</td>
            </tr>
            <tr valign="top">
              <td>Sweden</td>
              <td>411 (14.1)</td>
              <td>2917 (78.6)</td>
            </tr>
            <tr valign="top">
              <td>Denmark</td>
              <td>321 (11.8)</td>
              <td>3053 (81.9)</td>
            </tr>
          </tbody>
        </table>
      </table-wrap>
      <fig id="figure1" position="float">
        <label>Figure 1</label>
        <caption>
          <p>Percentages of users and non–internet users in the high isolation group by country.</p>
        </caption>
        <graphic xlink:href="jmir_v24i1e20466_fig1.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
      </fig>
      <p>In <xref ref-type="table" rid="table2">Table 2</xref>, we can observe the sociodemographic, economic, and health characteristics of the individuals who participated in this study, according to their degree of social isolation. The group of individuals who experience high levels of social isolation includes a majority of older female adults, who have on average fewer years of schooling in relation to their counterparts experiencing low levels of social isolation. Similarly, a higher percentage of the more socially isolated individuals reported having a negative financial situation.</p>
      <p>With regard to social networks, the more isolated individuals are more geographically distant from members of their network than their less isolated counterparts. Likewise, more socially isolated individuals also experience greater feelings of loneliness.</p>
      <p>Finally, with regard to mental and physical health, individuals experiencing high levels of social isolation also report more depressive symptoms and physical inactivity than their less isolated peers.</p>
      <p>In <xref ref-type="table" rid="table3">Table 3</xref>, we can observe a negative association between internet use and social isolation, after controlling for a set of sociodemographic, economic, and health characteristics of the individuals, described in the literature as determinants of social isolation. Indeed, in most of the countries analyzed, internet use relates to a decreased likelihood of high levels of social isolation.</p>
      <p>Denmark is the country where internet users are less likely to experience high levels of social isolation compared to nonusers. In this country, internet users are 72.2% less likely (OR 0.278, 95% CI 0.196-0.396) to be in a situation of high social isolation. Similarly, in France, Sweden, Luxembourg, Germany, Czech Republic, Estonia, Switzerland, Austria, Italy, Slovenia, and Spain, internet users are less likely to experience high levels of social isolation than nonusers. In Portugal, Poland, Greece, and Croatia, internet users were not less likely to experience high social isolation. Outside the European context, more specifically in Israel, internet users were 42.7% less likely (OR 0.573, 95% CI 0.383 to 0.856) to experience high levels of social isolation.</p>
      <table-wrap position="float" id="table2">
        <label>Table 2</label>
        <caption>
          <p>Descriptive statistics of the variables studied according to degree of social isolation (N=67,173). Source: Survey of Health, Ageing and Retirement in Europe wave 6, version 7.0.0; weighted data.</p>
        </caption>
        <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
          <col width="30"/>
          <col width="30"/>
          <col width="280"/>
          <col width="0"/>
          <col width="170"/>
          <col width="0"/>
          <col width="170"/>
          <col width="0"/>
          <col width="120"/>
          <col width="0"/>
          <col width="80"/>
          <col width="0"/>
          <col width="120"/>
          <thead>
            <tr valign="bottom">
              <td colspan="4">Variable</td>
              <td colspan="2">High social isolation (n=11,614)</td>
              <td colspan="2">Low social isolation (n=55,559)</td>
              <td colspan="2"><italic>χ</italic><sup>2</sup>/t (<italic>df</italic>)</td>
              <td colspan="2"><italic>P</italic> value</td>
              <td>Effect size (Cohen <italic>d/φ</italic>)</td>
            </tr>
          </thead>
          <tbody>
            <tr valign="top">
              <td colspan="13">
                <bold>Sociodemographic and economic characteristics</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td colspan="3">Age (years), mean (SD)</td>
              <td colspan="2">70.05 (11.95)</td>
              <td colspan="2">65.07 (10.26)</td>
              <td colspan="2">48.781 (1)</td>
              <td colspan="2">&#60;.001</td>
              <td>0.498 (small)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td colspan="7">
                <bold>Sex, n (%)</bold>
              </td>
              <td colspan="2">1457.933 (1)</td>
              <td colspan="2">&#60;.001</td>
              <td>0.147 (small)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Female</td>
              <td colspan="2">8359 (67.6)</td>
              <td colspan="2">29,243 (50.3)</td>
              <td colspan="2">
                <break/>
              </td>
              <td colspan="2">
                <break/>
              </td>
              <td colspan="2">
                <break/>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Male</td>
              <td colspan="2">3255 (32.4)</td>
              <td colspan="2">26,316 (49.7)</td>
              <td colspan="2">
                <break/>
              </td>
              <td colspan="2">
                <break/>
              </td>
              <td colspan="2">
                <break/>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td colspan="3">Schooling (years), mean (SD)</td>
              <td colspan="2">9.51 (4.26)</td>
              <td colspan="2">11.17 (4.51)</td>
              <td colspan="2">–32.922 (1)</td>
              <td colspan="2">&#60;.001</td>
              <td>0.344 (small)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td colspan="7">
                <bold>Financial situation, n (%)</bold>
              </td>
              <td colspan="2">976.178 (1)</td>
              <td colspan="2">&#60;.001</td>
              <td>0.122 (small)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Positive</td>
              <td colspan="2">5309 (48.1)</td>
              <td colspan="2">34,471 (64.5)</td>
              <td colspan="2">
                <break/>
              </td>
              <td colspan="2">
                <break/>
              </td>
              <td colspan="2">
                <break/>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Negative</td>
              <td colspan="2">5799 (51.9)</td>
              <td colspan="2">19,669 (35.5)</td>
              <td colspan="2">
                <break/>
              </td>
              <td colspan="2">
                <break/>
              </td>
              <td colspan="2">
                <break/>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td colspan="3">Geographical distance from social network (km), mean (SD)</td>
              <td colspan="2">3.89 (1.57)</td>
              <td colspan="2">3.06 (1.61)</td>
              <td colspan="2">58.917 (1)</td>
              <td colspan="2">&#60;.001</td>
              <td>0.652 (medium)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td colspan="3">Loneliness, mean (SD)</td>
              <td colspan="2">4.66 (1.78)</td>
              <td colspan="2">3.78 (1.27)</td>
              <td colspan="2">52.414 (1)</td>
              <td colspan="2">&#60;.001</td>
              <td>0.540 (medium)</td>
            </tr>
            <tr valign="top">
              <td colspan="13">
                <bold>Health</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td colspan="7">
                <bold>Exhibits depressive symptoms, n (%)</bold>
              </td>
              <td colspan="2">1327.652 (1)</td>
              <td colspan="2">&#60;.001</td>
              <td>0.144 (small)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Yes</td>
              <td colspan="2">4697 (43.0)</td>
              <td colspan="2">12,751 (25.9)</td>
              <td colspan="2">
                <break/>
              </td>
              <td colspan="2">
                <break/>
              </td>
              <td colspan="2">
                <break/>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>No</td>
              <td colspan="2">6713 (57.0)</td>
              <td colspan="2">39,556 (74.1)</td>
              <td colspan="2">
                <break/>
              </td>
              <td colspan="2">
                <break/>
              </td>
              <td colspan="2">
                <break/>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td colspan="7">
                <bold>Limitations in activities of daily living, n (%)</bold>
              </td>
              <td colspan="2">662.02 (1)</td>
              <td colspan="2">&#60;.001</td>
              <td>0.099<break/>(trivial)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>≥1</td>
              <td colspan="2">2253 (18.9)</td>
              <td colspan="2">5977 (11.0)</td>
              <td colspan="2">
                <break/>
              </td>
              <td colspan="2">
                <break/>
              </td>
              <td colspan="2">
                <break/>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>None</td>
              <td colspan="2">9358 (81.1)</td>
              <td colspan="2">49,440 (89.0)</td>
              <td colspan="2">
                <break/>
              </td>
              <td colspan="2">
                <break/>
              </td>
              <td colspan="2">
                <break/>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td colspan="7">
                <bold>Physical activity, n (%)</bold>
              </td>
              <td colspan="2">925.115 (1)</td>
              <td colspan="2">&#60;.001</td>
              <td>0.117 (small)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Inactive</td>
              <td colspan="2">2434 (23.5)</td>
              <td colspan="2">5929 (12.2)</td>
              <td colspan="2">
                <break/>
              </td>
              <td colspan="2">
                <break/>
              </td>
              <td colspan="2">
                <break/>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Active</td>
              <td colspan="2">9178 (76.5)</td>
              <td colspan="2">49,473 (87.8)</td>
              <td colspan="2">
                <break/>
              </td>
              <td colspan="2">
                <break/>
              </td>
              <td colspan="2">
                <break/>
              </td>
            </tr>
          </tbody>
        </table>
      </table-wrap>
      <table-wrap position="float" id="table3">
        <label>Table 3</label>
        <caption>
          <p>Statistics related to the importance of the internet as a determinant of a high level of isolation in individuals aged ≥50 years. Data source: Survey of Health, Ageing and Retirement in Europe wave 6, version 7.0.0 (unweighted).</p>
        </caption>
        <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
          <col width="250"/>
          <col width="250"/>
          <col width="250"/>
          <col width="250"/>
          <thead>
            <tr valign="bottom">
              <td>Country<sup>a</sup></td>
              <td>B<sup>b</sup></td>
              <td>aOR<sup>c</sup> (95% CI)</td>
              <td><italic>P</italic> value</td>
            </tr>
          </thead>
          <tbody>
            <tr valign="top">
              <td>Austria</td>
              <td>–0.616</td>
              <td>0.540 (0.419-0.697)</td>
              <td>&#60;.001</td>
            </tr>
            <tr valign="top">
              <td>Germany</td>
              <td>–0.797</td>
              <td>0.451 (0.352-0.576)</td>
              <td>&#60;.001</td>
            </tr>
            <tr valign="top">
              <td>Sweden</td>
              <td>–0.842</td>
              <td>0.431 (0.316-0.588)</td>
              <td>&#60;.001</td>
            </tr>
            <tr valign="top">
              <td>Spain</td>
              <td>–0.328</td>
              <td>0.720 (0.558-0.931)</td>
              <td>.01</td>
            </tr>
            <tr valign="top">
              <td>Italy</td>
              <td>–0.554</td>
              <td>0.574 (0.415-0.795)</td>
              <td>.001</td>
            </tr>
            <tr valign="top">
              <td>France</td>
              <td>–0.909</td>
              <td>0.403 (0.312-0.520)</td>
              <td>&#60;.001</td>
            </tr>
            <tr valign="top">
              <td>Denmark</td>
              <td>–1.279</td>
              <td>0.278 (0.196-0.396)</td>
              <td>&#60;.001</td>
            </tr>
            <tr valign="top">
              <td>Greece</td>
              <td>–0.062</td>
              <td>0.940 (0.717-1.232)</td>
              <td>.65</td>
            </tr>
            <tr valign="top">
              <td>Switzerland</td>
              <td>–0.675</td>
              <td>0.509 (0.376-0.690)</td>
              <td>&#60;.001</td>
            </tr>
            <tr valign="top">
              <td>Belgium</td>
              <td>–0.808</td>
              <td>0.448 (0.356-0.557)</td>
              <td>&#60;.001</td>
            </tr>
            <tr valign="top">
              <td>Israel</td>
              <td>–0.557</td>
              <td>0.573 (0.383-0.856)</td>
              <td>.007</td>
            </tr>
            <tr valign="top">
              <td>Czech Republic</td>
              <td>–0.795</td>
              <td>0.452 (0.367-0.557)</td>
              <td>&#60;.001</td>
            </tr>
            <tr valign="top">
              <td>Poland</td>
              <td>–0.166</td>
              <td>0.847 (0.521-1.377)</td>
              <td>.50</td>
            </tr>
            <tr valign="top">
              <td>Luxembourg</td>
              <td>–0.802</td>
              <td>0.448 (0.275-0.732)</td>
              <td>.001</td>
            </tr>
            <tr valign="top">
              <td>Portugal</td>
              <td>0.351</td>
              <td>1.421 (0.862-2.342)</td>
              <td>.168</td>
            </tr>
            <tr valign="top">
              <td>Slovenia</td>
              <td>–0.500</td>
              <td>0.606 (0.430-0.856)</td>
              <td>.004</td>
            </tr>
            <tr valign="top">
              <td>Estonia</td>
              <td>–0.788</td>
              <td>0.455 (0.371-0.557)</td>
              <td>&#60;.001</td>
            </tr>
            <tr valign="top">
              <td>Croatia</td>
              <td>–0.300</td>
              <td>0.741 (0.529-1.038)</td>
              <td>.08</td>
            </tr>
          </tbody>
        </table>
        <table-wrap-foot>
          <fn id="table3fn1">
            <p><sup>a</sup>Unweighted n values: Austria, 2523; Germany, 3853; Sweden, 3205; Spain, 4079; Italy, 3297; France, 2904; Denmark, 3110; Greece, 4128; Switzerland, 2329; Belgium, 3999; Israel, 1242; Czech Republic, 3941; Poland, 1161; Luxembourg, 1394; Portugal, 1284; Slovenia, 2523; Estonia, 4154; Croatia, 2274.</p>
          </fn>
          <fn id="table3fn2">
            <p><sup>b</sup>B: Standardized Coefficients</p>
          </fn>
          <fn id="table3fn3">
            <p><sup>c</sup>aOR: adjusted odds ratio from the logistic regression with adjustment for age, gender, years of schooling, self-perception of financial stress, limitations to activities of daily life, EURO-D score, physical inactivity, geographical distance from social network, and loneliness.</p>
          </fn>
        </table-wrap-foot>
      </table-wrap>
    </sec>
    <sec sec-type="discussion">
      <title>Discussion</title>
      <sec>
        <title>Principal Findings</title>
        <p>The aim of this study was to analyze the relationship between internet use and social isolation of individuals aged ≥50 years. The results evidence that in most of the European countries analyzed, as well as in Israel, use of the internet by adults aged ≥50 years is related to a decreased likelihood of high levels of social isolation. Thus, this study contributes to the open debate in literature [<xref ref-type="bibr" rid="ref37">37</xref>,<xref ref-type="bibr" rid="ref50">50</xref>] for which other surveys present contradictory results. This could be related to the results of other studies [<xref ref-type="bibr" rid="ref11">11</xref>,<xref ref-type="bibr" rid="ref20">20</xref>,<xref ref-type="bibr" rid="ref67">67</xref>] that suggest that the internet may facilitate communication and therefore enable individuals to maintain important contacts [<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref39">39</xref>,<xref ref-type="bibr" rid="ref68">68</xref>]. The internet may therefore contribute to less social isolation, even in less favorable contexts [<xref ref-type="bibr" rid="ref12">12</xref>], such as when older people live at a greater geographical distance from elements of their social networks following retirement, migration, or a change in residence for other reasons [<xref ref-type="bibr" rid="ref2">2</xref>,<xref ref-type="bibr" rid="ref12">12</xref>-<xref ref-type="bibr" rid="ref15">15</xref>]. However, the impact of ICT cannot be explained solely in terms of the fact that it creates opportunities for communication. The literature reveals that it counters social isolation by enabling people to obtain social support and motivating individuals to participate more in activities that interest them, because it contributes to self-confidence [<xref ref-type="bibr" rid="ref37">37</xref>] and facilitates access to services [<xref ref-type="bibr" rid="ref69">69</xref>].</p>
        <p>In this study, it was also possible to verify that in the European context, countries in Eastern and Southern Europe had the highest percentages of individuals experiencing high levels of social isolation. This result is consistent with results in other studies comparing the northern European countries with southern European countries, which indicate the existence of greater social isolation in the southern countries [<xref ref-type="bibr" rid="ref70">70</xref>]. In line with other research [<xref ref-type="bibr" rid="ref3">3</xref>,<xref ref-type="bibr" rid="ref10">10</xref>,<xref ref-type="bibr" rid="ref11">11</xref>], this study concludes that high levels of social isolation are more common in older female individuals [<xref ref-type="bibr" rid="ref71">71</xref>]. This finding contradicts the results of other research that identifies men as being more isolated than women [<xref ref-type="bibr" rid="ref13">13</xref>,<xref ref-type="bibr" rid="ref18">18</xref>]. The results also reveal that the most isolated individuals also have more financial difficulties, as noted in other research [<xref ref-type="bibr" rid="ref3">3</xref>,<xref ref-type="bibr" rid="ref13">13</xref>,<xref ref-type="bibr" rid="ref18">18</xref>], and they experience higher levels of loneliness, as also noted in other research [<xref ref-type="bibr" rid="ref19">19</xref>]. In this study, individuals in situations of high social isolation also reported being more geographically distant from their social network. The impact of increased geographical distance on establishing social interactions at an older age was previously underlined by other surveys showing that one of the main reasons for losing elements of adult social networks is a change in residence of these individuals [<xref ref-type="bibr" rid="ref72">72</xref>]. In terms of health, people experiencing high levels of social isolation also report being frailer, both physically and mentally [<xref ref-type="bibr" rid="ref3">3</xref>,<xref ref-type="bibr" rid="ref18">18</xref>].</p>
        <p>However, as previously mentioned, the main contribution of the study is that after controlling for the impact of these variables, internet use is associated with lower risk of social isolation.</p>
      </sec>
      <sec>
        <title>Limitations</title>
        <p>This study has several limitations. The main limitation is that a single item was used to measure overall internet use. Nevertheless, a yes/no response to whether someone regularly uses the internet has frequently been used to assess internet use by older people [<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref45">45</xref>,<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref67">67</xref>]. In the same vein, this measure was used in the SHARE project. Nonetheless, considering that the impact of the internet in the social sphere depends on the type of activities conducted on the web [<xref ref-type="bibr" rid="ref73">73</xref>-<xref ref-type="bibr" rid="ref75">75</xref>], it is important for future studies to consider the impact that different uses of the internet may have on social isolation. Furthermore, future research should consider longitudinal analyses to explore causality.</p>
      </sec>
      <sec>
        <title>Conclusion</title>
        <p>The results of this research contribute to the scientific debate about the relationship between internet use and social isolation, showing that even after controlling for the main determinants of social isolation, the use of the internet is related to lower levels of isolation in several countries.</p>
        <p>These results indicate the importance of developing public policies in Europe aimed at increasing rates of internet use as a way to ensure e-inclusion and prevent social isolation at an older age.</p>
      </sec>
    </sec>
  </body>
  <back>
    <app-group/>
    <glossary>
      <title>Abbreviations</title>
      <def-list>
        <def-item>
          <term id="abb1">OR</term>
          <def>
            <p>odds ratio</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb2">R-UCLA</term>
          <def>
            <p>Revised UCLA Loneliness Scale</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb3">SHARE</term>
          <def>
            <p>Survey of Health, Ageing and Retirement in Europe</p>
          </def>
        </def-item>
      </def-list>
    </glossary>
    <fn-group>
      <fn fn-type="conflict">
        <p>None declared.</p>
      </fn>
    </fn-group>
    <ref-list>
      <ref id="ref1">
        <label>1</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
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              <given-names>J</given-names>
            </name>
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              <surname>Havens</surname>
              <given-names>B</given-names>
            </name>
          </person-group>
          <article-title>Cross-national Comparisons of Social Isolation and Loneliness: Introduction and Overview</article-title>
          <source>Can. J. Aging</source>
          <year>2010</year>
          <month>03</month>
          <day>31</day>
          <volume>23</volume>
          <issue>2</issue>
          <fpage>109</fpage>
          <lpage>113</lpage>
          <pub-id pub-id-type="doi">10.1353/cja.2004.0021</pub-id>
        </nlm-citation>
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              <given-names>A</given-names>
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