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<article xmlns:xlink="http://www.w3.org/1999/xlink" article-type="review-article" dtd-version="2.0">
  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JMIR</journal-id>
      <journal-id journal-id-type="nlm-ta">J Med Internet Res</journal-id>
      <journal-title>Journal of Medical Internet Research</journal-title>
      <issn pub-type="epub">1438-8871</issn>
      <publisher>
        <publisher-name>JMIR Publications</publisher-name>
        <publisher-loc>Toronto, Canada</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">v22i9e18621</article-id>
      <article-id pub-id-type="pmid">32915156</article-id>
      <article-id pub-id-type="doi">10.2196/18621</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Review</subject>
        </subj-group>
        <subj-group subj-group-type="article-type">
          <subject>Review</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Effectiveness of Individual Real-Time Video Counseling on Smoking, Nutrition, Alcohol, Physical Activity, and Obesity Health Risks: Systematic Review</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="editor">
          <name>
            <surname>Eysenbach</surname>
            <given-names>Gunther</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib contrib-type="reviewer">
          <name>
            <surname>allman-Farinelli</surname>
            <given-names>Margaret</given-names>
          </name>
        </contrib>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Nomura</surname>
            <given-names>Akihiro</given-names>
          </name>
        </contrib>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Lippke</surname>
            <given-names>Sonia</given-names>
          </name>
        </contrib>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Muto</surname>
            <given-names>Tomoyasu</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib id="contrib1" contrib-type="author" corresp="yes">
          <name name-style="western">
            <surname>Byaruhanga</surname>
            <given-names>Judith</given-names>
          </name>
          <degrees>MPH</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <xref rid="aff2" ref-type="aff">2</xref>
          <address>
            <institution>Hunter New England Population Health</institution>
            <addr-line>Locked Bag 10</addr-line>
            <addr-line>Wallsend, </addr-line>
            <country>Australia</country>
            <phone>61 249246454</phone>
            <email>judith.byaruhanga@uon.edu.au</email>
          </address>
          <xref rid="aff3" ref-type="aff">3</xref>
          <xref rid="aff4" ref-type="aff">4</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0003-0382-1552</ext-link>
        </contrib>
        <contrib id="contrib2" contrib-type="author">
          <name name-style="western">
            <surname>Atorkey</surname>
            <given-names>Prince</given-names>
          </name>
          <degrees>MPhil</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <xref rid="aff2" ref-type="aff">2</xref>
          <xref rid="aff3" ref-type="aff">3</xref>
          <xref rid="aff4" ref-type="aff">4</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0001-9665-1139</ext-link>
        </contrib>
        <contrib id="contrib3" contrib-type="author">
          <name name-style="western">
            <surname>McLaughlin</surname>
            <given-names>Matthew</given-names>
          </name>
          <degrees>BSc</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <xref rid="aff2" ref-type="aff">2</xref>
          <xref rid="aff3" ref-type="aff">3</xref>
          <xref rid="aff4" ref-type="aff">4</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0003-2870-8556</ext-link>
        </contrib>
        <contrib id="contrib4" contrib-type="author">
          <name name-style="western">
            <surname>Brown</surname>
            <given-names>Alison</given-names>
          </name>
          <degrees>BClinSc, BNutrDiet (Hons)</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <xref rid="aff2" ref-type="aff">2</xref>
          <xref rid="aff3" ref-type="aff">3</xref>
          <xref rid="aff4" ref-type="aff">4</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-4233-7467</ext-link>
        </contrib>
        <contrib id="contrib5" contrib-type="author">
          <name name-style="western">
            <surname>Byrnes</surname>
            <given-names>Emma</given-names>
          </name>
          <degrees>BSocSc (Hons)</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <xref rid="aff3" ref-type="aff">3</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0001-6168-0167</ext-link>
        </contrib>
        <contrib id="contrib6" contrib-type="author">
          <name name-style="western">
            <surname>Paul</surname>
            <given-names>Christine</given-names>
          </name>
          <degrees>PhD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <xref rid="aff3" ref-type="aff">3</xref>
          <xref rid="aff4" ref-type="aff">4</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-0504-5246</ext-link>
        </contrib>
        <contrib id="contrib7" contrib-type="author">
          <name name-style="western">
            <surname>Wiggers</surname>
            <given-names>John</given-names>
          </name>
          <degrees>PhD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <xref rid="aff2" ref-type="aff">2</xref>
          <xref rid="aff3" ref-type="aff">3</xref>
          <xref rid="aff4" ref-type="aff">4</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0001-6361-9685</ext-link>
        </contrib>
        <contrib id="contrib8" contrib-type="author">
          <name name-style="western">
            <surname>Tzelepis</surname>
            <given-names>Flora</given-names>
          </name>
          <degrees>PhD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <xref rid="aff2" ref-type="aff">2</xref>
          <xref rid="aff3" ref-type="aff">3</xref>
          <xref rid="aff4" ref-type="aff">4</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-9914-2732</ext-link>
        </contrib>
      </contrib-group>
      <aff id="aff1">
        <label>1</label>
        <institution>School of Medicine and Public Health</institution>
        <institution>University of Newcastle</institution>
        <addr-line>Callaghan</addr-line>
        <country>Australia</country>
      </aff>
      <aff id="aff2">
        <label>2</label>
        <institution>Hunter New England Population Health</institution>
        <addr-line>Wallsend</addr-line>
        <country>Australia</country>
      </aff>
      <aff id="aff3">
        <label>3</label>
        <institution>Hunter Medical Research Institute</institution>
        <addr-line>New Lambton Heights</addr-line>
        <country>Australia</country>
      </aff>
      <aff id="aff4">
        <label>4</label>
        <institution>Priority Research Centre for Health Behaviour</institution>
        <institution>Faculty of Health &#38; Medicine</institution>
        <institution>University of Newcastle</institution>
        <addr-line>Callaghan</addr-line>
        <country>Australia</country>
      </aff>
      <author-notes>
        <corresp>Corresponding Author: Judith Byaruhanga <email>judith.byaruhanga@uon.edu.au</email></corresp>
      </author-notes>
      <pub-date pub-type="collection">
        <month>9</month>
        <year>2020</year>
      </pub-date>
      <pub-date pub-type="epub">
        <day>11</day>
        <month>9</month>
        <year>2020</year>
      </pub-date>
      <volume>22</volume>
      <issue>9</issue>
      <elocation-id>e18621</elocation-id>
      <history>
        <date date-type="received">
          <day>9</day>
          <month>3</month>
          <year>2020</year>
        </date>
        <date date-type="rev-request">
          <day>12</day>
          <month>6</month>
          <year>2020</year>
        </date>
        <date date-type="rev-recd">
          <day>18</day>
          <month>7</month>
          <year>2020</year>
        </date>
        <date date-type="accepted">
          <day>26</day>
          <month>7</month>
          <year>2020</year>
        </date>
      </history>
      <copyright-statement>©Judith Byaruhanga, Prince Atorkey, Matthew McLaughlin, Alison Brown, Emma Byrnes, Christine Paul, John Wiggers, Flora Tzelepis. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 11.09.2020.</copyright-statement>
      <copyright-year>2020</copyright-year>
      <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
        <p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Journal of Medical Internet Research, is properly cited. The complete bibliographic information, a link to the original publication on http://www.jmir.org/, as well as this copyright and license information must be included.</p>
      </license>
      <self-uri xlink:href="http://www.jmir.org/2020/9/e18621/" xlink:type="simple"/>
      <abstract>
        <sec sec-type="background">
          <title>Background</title>
          <p>Real-time video communication technology allows virtual face-to-face interactions between the provider and the user, and can be used to modify risk factors for smoking, nutrition, alcohol consumption, physical activity, and obesity. No systematic reviews have examined the effectiveness of individual real-time video counseling for addressing each of the risk factors for smoking, nutrition, alcohol consumption, physical activity, and obesity.</p>
        </sec>
        <sec sec-type="objective">
          <title>Objective</title>
          <p>This systematic review aims to examine the effectiveness of individually delivered real-time video counseling on risk factors for smoking, nutrition, alcohol consumption, physical activity, and obesity.</p>
        </sec>
        <sec sec-type="methods">
          <title>Methods</title>
          <p>The MEDLINE (Medical Literature Analysis and Retrieval System Online), EMBASE (Excerpta Medica Database), PsycINFO, Cochrane Register of Controlled Trials, and Scopus databases were searched for eligible studies published up to November 21, 2019. Eligible studies were randomized or cluster randomized trials that tested the effectiveness of individual real-time video communication interventions on smoking, nutrition, alcohol, physical activity, and obesity in any population or setting; the comparator was a no-intervention control group or any other mode of support (eg, telephone); and an English-language publication.</p>
        </sec>
        <sec sec-type="results">
          <title>Results</title>
          <p>A total of 13 studies were eligible. Four studies targeted smoking, 3 alcohol, 3 physical activity, and 3 obesity. In 2 of the physical activity studies, real-time video counseling was found to significantly increase physical activity when compared with usual care at week 9 and after 5 years. Two obesity studies found a significant change in BMI between a video counseling and a documents group, with significantly greater weight loss in the video counseling group than the in-person as well as the control groups. One study found that those in the video counseling group were significantly more likely than those in the telephone counseling group to achieve smoking cessation. The remaining studies found no significant differences between video counseling and telephone counseling or face-to-face counseling for smoking cessation, video counseling and face-to-face treatment on alcohol consumption, video counseling and no counseling for physical activity, and video counseling and face-to-face treatment on BMI. The global methodological quality rating was moderate in 1 physical activity study, whereas 12 studies had a weak global rating.</p>
        </sec>
        <sec sec-type="conclusions">
          <title>Conclusions</title>
          <p>Video counseling is potentially more effective than a control group or other modes of support in addressing physical inactivity and obesity and is not less effective in modifying smoking and alcohol consumption. Further research is required to determine the relative benefits of video counseling in terms of other policy and practice decision-making factors such as costs and feasibility.</p>
        </sec>
      </abstract>
      <kwd-group>
        <kwd>telehealth</kwd>
        <kwd>videoconferencing</kwd>
        <kwd>smoking cessation</kwd>
        <kwd>diet</kwd>
        <kwd>alcohol drinking</kwd>
        <kwd>physical activity</kwd>
        <kwd>obesity</kwd>
        <kwd>mobile phone</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec sec-type="introduction">
      <title>Introduction</title>
      <sec>
        <title>Background</title>
        <p>Tobacco use, poor nutrition, risky alcohol consumption, physical inactivity, and obesity are the leading modifiable health risks that can cause noncommunicable diseases, including cardiovascular disease, chronic respiratory disease, cancer, stroke, and diabetes [<xref ref-type="bibr" rid="ref1">1</xref>]. Globally, it is estimated that there are 1.1 billion tobacco smokers, and tobacco use is responsible for the death of 8 million people each year [<xref ref-type="bibr" rid="ref2">2</xref>]. Harmful alcohol consumption is responsible for 3 million deaths and causes &#62;200 chronic and acute diseases [<xref ref-type="bibr" rid="ref3">3</xref>]. Globally, in 2016, an estimated 0.9 million injury deaths and 52.4 million injury disability-adjusted life years (DALYs) were attributable to alcohol [<xref ref-type="bibr" rid="ref3">3</xref>]. Similarly, poor diet accounts for 11 million adult deaths [<xref ref-type="bibr" rid="ref4">4</xref>], of which 3 million annual deaths are attributed to excess salt or sodium intake [<xref ref-type="bibr" rid="ref5">5</xref>], 2 million deaths per year are attributable to diets low in fruits and vegetables, and 3 million deaths are attributable to low intake of whole grains [<xref ref-type="bibr" rid="ref4">4</xref>,<xref ref-type="bibr" rid="ref6">6</xref>]. Insufficient physical activity causes 5.3 million premature deaths annually [<xref ref-type="bibr" rid="ref7">7</xref>].</p>
        <p>Real-time video communication, also known as videoconferencing, telehealth, or telecare [<xref ref-type="bibr" rid="ref8">8</xref>], is a scalable and accessible intervention delivered over the internet via a video camera connected to a computer, smartphone, or tablet [<xref ref-type="bibr" rid="ref9">9</xref>]. Real-time video communication is available to the 3.9 billion people who have access to the internet worldwide [<xref ref-type="bibr" rid="ref10">10</xref>] and have a device with a video camera. Video communication software such as Skype can be downloaded for free by internet users and is widely used for personal or professional communication every day [<xref ref-type="bibr" rid="ref11">11</xref>]. Real-time video technology allows a real-time, virtual face-to-face interaction between the provider and the user [<xref ref-type="bibr" rid="ref12">12</xref>] at any time of the day in any location with internet access [<xref ref-type="bibr" rid="ref13">13</xref>]. Another advantage of real-time video counseling is that it provides a mode for delivering individual counseling that allows counselors to respond to the client’s verbal and nonverbal cues, unlike telephone support, which is an audio-only intervention, or written materials. Real-time video counseling is supported by the media richness theory, which conceptualizes that real-time video counseling ranks highly as a rich mode of communication as it provides virtual face-to-face support and advisers are able to respond to nonverbal cues, which is not possible in all forms of behavioral support [<xref ref-type="bibr" rid="ref14">14</xref>]. There is an opportunity for instant clarification of doubts or identifying reluctance or enthusiasm in both the voice and body language, consequently minimizing chances of being misunderstood. Real-time video counseling also eliminates travel time and associated costs of face-to-face interventions [<xref ref-type="bibr" rid="ref15">15</xref>], improves discretion and comfort as the video call can be taken in a preferred private place to avoid the potential stigma associated with clinic visits [<xref ref-type="bibr" rid="ref15">15</xref>,<xref ref-type="bibr" rid="ref16">16</xref>], and has widespread reach. Real-time video counseling has the potential to be used on a large scale to target health risks attributable to smoking, nutrition, alcohol consumption, physical activity, and obesity [<xref ref-type="bibr" rid="ref9">9</xref>,<xref ref-type="bibr" rid="ref10">10</xref>].</p>
        <p>Individual counseling is used by service providers to deliver support for smoking cessation [<xref ref-type="bibr" rid="ref17">17</xref>], nutrition [<xref ref-type="bibr" rid="ref18">18</xref>], physical activity [<xref ref-type="bibr" rid="ref19">19</xref>], obesity [<xref ref-type="bibr" rid="ref19">19</xref>], and alcohol consumption [<xref ref-type="bibr" rid="ref20">20</xref>]. Individual counseling is primarily delivered in person or via the telephone by service providers [<xref ref-type="bibr" rid="ref21">21</xref>-<xref ref-type="bibr" rid="ref24">24</xref>], and these modes have been found to be effective in improving health risks attributable to smoking, nutrition, alcohol consumption, physical activity, and obesity [<xref ref-type="bibr" rid="ref17">17</xref>-<xref ref-type="bibr" rid="ref19">19</xref>,<xref ref-type="bibr" rid="ref25">25</xref>-<xref ref-type="bibr" rid="ref27">27</xref>]. The advantages of individual counseling include convenient scheduling for both the client and service provider, focused treatment with personalized feedback, and a high level of confidentiality as clients can disclose themselves in private compared with group counseling [<xref ref-type="bibr" rid="ref28">28</xref>].</p>
        <p>The capability, opportunity, motivation, and behavior (COM-B) model by Michie et al [<xref ref-type="bibr" rid="ref29">29</xref>] provides a theoretical framework to examine the effectiveness of real-time video counseling on health risks for smoking, nutrition, alcohol consumption, physical activity, and obesity. The COM-B model suggests that behavior is a result of 3 factors: capability (psychological or physical), opportunity (physical or social), and motivation (reflective or automatic) [<xref ref-type="bibr" rid="ref29">29</xref>]. Real-time video counseling may maximize capability, opportunity, and motivation to encourage behavior change in the following ways. First, a real-time video counseling intervention for health risks of smoking, nutrition, alcohol consumption, physical activity, and obesity can assist participants in realizing their capability by enhancing their knowledge about effective behavior change methods, situations, and environments that act as triggers for their behaviors. Second, real-time video counseling may remove barriers such as the distance and time to travel to access face-to-face treatment, thereby increasing the opportunity for behavior change. Third, real-time video counseling can include motivational interviewing and cognitive behavioral therapy techniques to increase motivation to improve factors for smoking, nutrition, alcohol consumption, physical activity, and obesity [<xref ref-type="bibr" rid="ref29">29</xref>].</p>
        <p>One systematic review has examined the effectiveness of various technology-based interventions on smoking cessation, including real-time video counseling; however, the review only included studies of participants with low socioeconomic status or disadvantaged populations [<xref ref-type="bibr" rid="ref30">30</xref>]. This review identified only 1 study that found no significant difference between video counseling and telephone counseling on smoking cessation [<xref ref-type="bibr" rid="ref31">31</xref>]. A Cochrane systematic review examined the effectiveness of real-time video counseling for smoking cessation only and found limited evidence that suggested no difference between video counseling and telephone counseling [<xref ref-type="bibr" rid="ref32">32</xref>]. However, this systematic review excluded studies that measured smoking cessation &#60;6 months postbaseline [<xref ref-type="bibr" rid="ref32">32</xref>]. To the best of our knowledge, there are no other systematic reviews that have examined the effectiveness of individual real-time video support for addressing each of the risk factors for smoking, nutrition, alcohol consumption, physical activity, and obesity.</p>
      </sec>
      <sec>
        <title>Objective</title>
        <p>This systematic review aimed to examine the effectiveness of individual real-time video counseling on health risks for smoking, nutrition, alcohol, physical inactivity, and obesity relative to (1) a no-intervention control group or (2) other modes of intervention delivery.</p>
      </sec>
    </sec>
    <sec sec-type="methods">
      <title>Methods</title>
      <sec>
        <title>Narrative Review</title>
        <p>This narrative review follows the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) [<xref ref-type="bibr" rid="ref33">33</xref>] and was completed as per the protocol registered with the International Prospective Register of Systematic Reviews (PROSPERO; registration number: CRD42017071885). Meta-analyses were not undertaken because of the heterogeneity between studies (eg, clinical vs nonclinical populations) and the small number of studies examining the effectiveness of real-time video counseling for each risk factor for smoking, nutrition, alcohol consumption, physical activity, and obesity.</p>
      </sec>
      <sec>
        <title>Search Strategy</title>
        <p>The electronic databases Cochrane Register of Controlled Trials (via Cochrane Library), MEDLINE (Medical Literature Analysis and Retrieval System Online; from 1946), EMBASE (Excerpta Medica dataBASE; from 1947), PsycINFO (from 1806), and Scopus were searched from inception to retrieve studies published up to November 21, 2019, that described a real-time video counseling intervention (eg, video conferencing or video consultation or telehealth or telemedicine) for modifying health risks for smoking, nutrition, alcohol consumption, physical activity, and obesity. The reference lists of included trials were also manually searched to retrieve any other relevant studies.</p>
        <p>The database search consisted of focused text word searches and medical subject heading searches. The search terms were divided into 3 groups: (1) smoking, nutrition, alcohol, physical activity, and obesity behavior (ie, tobacco use, nutrition, alcohol drinking, physical activity, obesity, healthy lifestyle, lifestyle), (2) video communication intervention (ie, telemedicine, videoconferencing, remote consultation, Skype, Viber, webcam, Talky Core, WhatsApp, FaceTime, Messenger, Google Hangouts), and (3) study design (ie, randomized controlled trial, cluster randomized trial). <xref ref-type="boxed-text" rid="box1">Textbox 1</xref> outlines the search strategy.</p>
        <boxed-text id="box1" position="float">
          <title>Search strategy.</title>
          <list list-type="bullet">
            <list-item>
              <p>Nicotine/</p>
            </list-item>
            <list-item>
              <p>Tobacco/</p>
            </list-item>
            <list-item>
              <p>exp “Tobacco Use Cessation”/</p>
            </list-item>
            <list-item>
              <p>exp “Tobacco Use”/</p>
            </list-item>
            <list-item>
              <p>(Cigar* or smok* or tobacco or nicotine).tw.</p>
            </list-item>
            <list-item>
              <p>1 or 2 or 3 or 4 or 5</p>
            </list-item>
            <list-item>
              <p>exp Healthy Lifestyle/</p>
            </list-item>
            <list-item>
              <p>exp Life Style/</p>
            </list-item>
            <list-item>
              <p>(lifestyle* or life style*).tw.</p>
            </list-item>
            <list-item>
              <p>nutrition*.mp.</p>
            </list-item>
            <list-item>
              <p>exp Fruit/</p>
            </list-item>
            <list-item>
              <p>exp Vegetables/</p>
            </list-item>
            <list-item>
              <p>(fruit* or vegetable*).tw.</p>
            </list-item>
            <list-item>
              <p>7 or 8 or 9 or 10 or 11 or 12 or 13</p>
            </list-item>
            <list-item>
              <p>exp Alcohol Drinking/</p>
            </list-item>
            <list-item>
              <p>exp Alcoholism/ or exp Drinking Behavior/</p>
            </list-item>
            <list-item>
              <p>exp Alcoholic Intoxication/</p>
            </list-item>
            <list-item>
              <p>(Alcohol* or drinking).tw.</p>
            </list-item>
            <list-item>
              <p>15 or 16 or 17 or 18</p>
            </list-item>
            <list-item>
              <p>exp Exercise/</p>
            </list-item>
            <list-item>
              <p>physical activity.mp.</p>
            </list-item>
            <list-item>
              <p>exp Sedentary Lifestyle/</p>
            </list-item>
            <list-item>
              <p>(physical activit* or physical inactivit*).tw.</p>
            </list-item>
            <list-item>
              <p>(exercise* or Sport*).tw.</p>
            </list-item>
            <list-item>
              <p>20 or 21 or 22 or 23 or 24</p>
            </list-item>
            <list-item>
              <p>exp Overweight/</p>
            </list-item>
            <list-item>
              <p>Obes*.tw.</p>
            </list-item>
            <list-item>
              <p>26 or 27</p>
            </list-item>
            <list-item>
              <p>exp Telemedicine/</p>
            </list-item>
            <list-item>
              <p>exp Videoconferencing/</p>
            </list-item>
            <list-item>
              <p>Remote Consultation/</p>
            </list-item>
            <list-item>
              <p>(skype or viber or webcam or talky core or whatsapp or facetime or messenger or google* hangouts).mp. (mp=title, abstract, original title, name of substance word, subject heading word, keyword heading word, protocol supplementary concept word, rare disease supplementary concept word, unique identifier, synonyms)</p>
            </list-item>
            <list-item>
              <p>((real time or realtime) adj3 (counsel* or support* or therap* or conference or consult*)).tw.</p>
            </list-item>
            <list-item>
              <p>(remote adj3 (communicat* or consult*)).tw.</p>
            </list-item>
            <list-item>
              <p>29 or 30 or 31 or 32 or 33 or 34</p>
            </list-item>
            <list-item>
              <p>6 or 14 or 19 or 25 or 28</p>
            </list-item>
            <list-item>
              <p>35 and 36</p>
            </list-item>
            <list-item>
              <p>exp Randomized Controlled Trial/</p>
            </list-item>
            <list-item>
              <p>exp Randomized Controlled Trials as Topic/</p>
            </list-item>
            <list-item>
              <p>exp Clinical Trial/</p>
            </list-item>
            <list-item>
              <p>exp Clinical Trials as Topic/</p>
            </list-item>
            <list-item>
              <p>exp Random Allocation/</p>
            </list-item>
            <list-item>
              <p>Random*.tw.</p>
            </list-item>
            <list-item>
              <p>Trial.tw.</p>
            </list-item>
            <list-item>
              <p>38 or 39 or 40 or 41 or 42 or 43 or 44</p>
            </list-item>
            <list-item>
              <p>37 and 45</p>
            </list-item>
          </list>
        </boxed-text>
      </sec>
      <sec>
        <title>Eligibility Criteria</title>
        <p>Studies were included in this review if they met the following criteria:</p>
        <list list-type="order">
          <list-item>
            <p>Study design: randomized trials or cluster randomized trials. Randomized trials and cluster randomized trials were included because these designs are considered the gold standard for measuring effectiveness [<xref ref-type="bibr" rid="ref34">34</xref>].</p>
          </list-item>
          <list-item>
            <p>Study participants: any population (ie, general population, patients).</p>
          </list-item>
          <list-item>
            <p>Setting: any setting, including community and health care settings.</p>
          </list-item>
          <list-item>
            <p>Intervention: video communication was used as the mode to deliver individual, one-on-one support (ie, Skype, FaceTime, Facebook Messenger, WhatsApp, or any preferred individual real-time video communication platform).</p>
          </list-item>
          <list-item>
            <p>Comparators: the comparators included a no-intervention control group or any other form of support to address the risk factors for smoking, nutrition, alcohol consumption, physical activity, and obesity, such as written materials, telephone counseling, web-based support, and face-to-face interventions.</p>
          </list-item>
          <list-item>
            <p>Language: studies published in English.</p>
          </list-item>
          <list-item>
            <p>Outcome measures: any measure of an individual’s smoking (eg, smoking cessation, quit attempts), nutrition (eg, serves of fruit and/or vegetables, calories), alcohol (eg, number of standard drinks of alcohol), physical activity (eg, number of minutes of moderate or vigorous physical activity or metabolic equivalent [MET] minutes), or obesity (eg, BMI, waist circumference).</p>
          </list-item>
        </list>
      </sec>
      <sec>
        <title>Study Selection</title>
        <p>After removing duplicate records, 2 authors (JB and FT, PA, or MM) independently screened the titles and abstracts of all records using either EndNote or Covidence. Papers that did not meet the eligibility criteria were excluded. Two reviewers independently examined the full text of the papers that were deemed eligible or whose eligibility was uncertain based on the title and abstract screening. Two reviewers met and discussed any discrepancies until a consensus was reached. The reasons for exclusion were recorded for all full text papers assessed that were ineligible.</p>
      </sec>
      <sec>
        <title>Data Extraction of Study Characteristics</title>
        <p>Two authors (JB and AB or EB) independently extracted the following data from eligible studies: authors and country, years data collected, study design, sample characteristics, recruitment method, eligibility criteria, participation rate, treatment conditions, the video intervention received, retention at follow-up, outcome measures, the comparators, and costs. All discrepancies were resolved between the 2 reviewers through discussion, and a third reviewer (FT) was consulted when necessary.</p>
      </sec>
      <sec>
        <title>Methodological Quality Assessment</title>
        <p>The quality assessment of each included study was assessed independently by 2 reviewers (JB and FT). The Quality Assessment Tool for Quantitative Studies developed by the Effective Public Health Practice Project was used to assess methodological quality [<xref ref-type="bibr" rid="ref35">35</xref>] according to the instructions described in the Quality Assessment Tool for Quantitative Studies Dictionary [<xref ref-type="bibr" rid="ref36">36</xref>]. The Quality Assessment Tool for Quantitative Studies assesses randomized and nonrandomized trials in relation to 6 components: selection bias, study design, confounders, blinding, data collection methods, withdrawals, and dropouts. Each study was rated as <italic>strong</italic>, <italic>moderate</italic>, or <italic>weak</italic> on each of these components. An overall global rating was then assigned to each study, with studies classified as <italic>strong</italic> (no weak ratings), <italic>moderate</italic> (1 weak rating), or <italic>weak</italic> (2 weak ratings).</p>
      </sec>
    </sec>
    <sec sec-type="results">
      <title>Results</title>
      <p>After removing duplicates, a total of 7991 records were screened. Of these, 7894 records were excluded at the title and abstract screening stage, and 97 full text records were assessed for eligibility (<xref rid="figure1" ref-type="fig">Figure 1</xref>). A total of 84 of the 97 full text records were excluded for the following reasons: 26 did not measure smoking, nutrition, alcohol consumption, physical activity, and obesity outcomes; 23 did not use any form of video counseling intervention; 19 involved group video counseling and not individual video counseling [<xref ref-type="bibr" rid="ref37">37</xref>-<xref ref-type="bibr" rid="ref54">54</xref>]; 3 were protocol papers [<xref ref-type="bibr" rid="ref55">55</xref>-<xref ref-type="bibr" rid="ref57">57</xref>]; 8 were not randomized studies [<xref ref-type="bibr" rid="ref58">58</xref>-<xref ref-type="bibr" rid="ref65">65</xref>]; 2 studies were ongoing [<xref ref-type="bibr" rid="ref32">32</xref>,<xref ref-type="bibr" rid="ref66">66</xref>]; 1 was a conference abstract [<xref ref-type="bibr" rid="ref67">67</xref>]; and 2 studies described a multicomponent intervention, and it was not possible to isolate the effect of real-time video counseling [<xref ref-type="bibr" rid="ref68">68</xref>,<xref ref-type="bibr" rid="ref69">69</xref>]. The remaining 13 eligible studies were included in the review. <xref rid="figure1" ref-type="fig">Figure 1</xref> presents the PRISMA diagram for screening and selection.</p>
      <fig id="figure1" position="float">
        <label>Figure 1</label>
        <caption>
          <p>PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) diagram of the screening and selection process. SNAPO: smoking, nutrition, alcohol consumption, physical activity, and obesity.</p>
        </caption>
        <graphic xlink:href="jmir_v22i9e18621_fig1.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
      </fig>
      <sec>
        <title>Study Characteristics</title>
        <p>Four studies focused on individual video counseling for smoking cessation [<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref70">70</xref>-<xref ref-type="bibr" rid="ref72">72</xref>], 3 studies focused on alcohol consumption [<xref ref-type="bibr" rid="ref73">73</xref>-<xref ref-type="bibr" rid="ref75">75</xref>], 3 studies focused on physical activity [<xref ref-type="bibr" rid="ref76">76</xref>-<xref ref-type="bibr" rid="ref78">78</xref>], and 3 studies focused on obesity [<xref ref-type="bibr" rid="ref79">79</xref>-<xref ref-type="bibr" rid="ref81">81</xref>]. No trial examined the effectiveness of real-time video counseling on nutrition. Most trials were funded by grants from the government [<xref ref-type="bibr" rid="ref76">76</xref>,<xref ref-type="bibr" rid="ref77">77</xref>,<xref ref-type="bibr" rid="ref79">79</xref>-<xref ref-type="bibr" rid="ref81">81</xref>] or university [<xref ref-type="bibr" rid="ref71">71</xref>,<xref ref-type="bibr" rid="ref73">73</xref>]. One study reported receiving no funding [<xref ref-type="bibr" rid="ref75">75</xref>], 1 study was funded by the Craig H. Neilsen Foundation [<xref ref-type="bibr" rid="ref78">78</xref>], and 1 study was funded by CureApp Inc [<xref ref-type="bibr" rid="ref72">72</xref>]. All 13 studies were published from 2010 onward.</p>
        <sec>
          <title>Smoking Cessation</title>
          <p>Three randomized trials that examined the effectiveness of real-time video counseling compared with telephone counseling for smoking cessation were conducted in the United States [<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref70">70</xref>,<xref ref-type="bibr" rid="ref71">71</xref>]. One trial conducted in Japan compared real-time video counseling with face-to-face counseling [<xref ref-type="bibr" rid="ref72">72</xref>]. The studies followed-up participants for 3 [<xref ref-type="bibr" rid="ref70">70</xref>], 6 [<xref ref-type="bibr" rid="ref71">71</xref>,<xref ref-type="bibr" rid="ref72">72</xref>], or 12 months [<xref ref-type="bibr" rid="ref31">31</xref>]. One trial focused on a clinical population of women with HIV [<xref ref-type="bibr" rid="ref71">71</xref>], whereas 3 studies included nonclinical populations [<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref70">70</xref>,<xref ref-type="bibr" rid="ref72">72</xref>]. The sample sizes were 49 [<xref ref-type="bibr" rid="ref70">70</xref>,<xref ref-type="bibr" rid="ref71">71</xref>], 115 [<xref ref-type="bibr" rid="ref72">72</xref>], and 566 participants [<xref ref-type="bibr" rid="ref31">31</xref>]. Two studies recruited women only [<xref ref-type="bibr" rid="ref70">70</xref>,<xref ref-type="bibr" rid="ref71">71</xref>], whereas another study had a majority of female participants (65%) [<xref ref-type="bibr" rid="ref31">31</xref>] and 1 study had a majority of male participants (81%) [<xref ref-type="bibr" rid="ref72">72</xref>]. Across the 4 trials, the mean age was 45 (SD 11.7) to 55 years (SD 11) [<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref70">70</xref>-<xref ref-type="bibr" rid="ref72">72</xref>]. The participation rates were 36.66% (566/1544) [<xref ref-type="bibr" rid="ref31">31</xref>], 52% (49/94) [<xref ref-type="bibr" rid="ref71">71</xref>], 64% (49/77) [<xref ref-type="bibr" rid="ref70">70</xref>], and unclear for 1 study [<xref ref-type="bibr" rid="ref72">72</xref>]. The retention rates at follow-up were 87.6% (496/566) at 12 months [<xref ref-type="bibr" rid="ref31">31</xref>], 55% (27/49) [<xref ref-type="bibr" rid="ref71">71</xref>] and 97.4% (112/115) [<xref ref-type="bibr" rid="ref72">72</xref>] at 6 months, and 78% (38/49) at 3 months [<xref ref-type="bibr" rid="ref70">70</xref>].</p>
          <p><xref ref-type="supplementary-material" rid="app1">Multimedia Appendix 1</xref> [<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref70">70</xref>-<xref ref-type="bibr" rid="ref72">72</xref>] provides a detailed description of the study characteristics. The trial in rural United States (Kansas) recruited participants from 20 primary care clinics and through community-based activities (eg, radio interviews, health fairs, and religious organizations) [<xref ref-type="bibr" rid="ref31">31</xref>], whereas another trial recruited Korean-American women through web-based communities and newspaper advertisements [<xref ref-type="bibr" rid="ref70">70</xref>]. The US trial among women living with HIV had participants referred by health workers, professional health networks, advertisements on free websites, and Craiglist [<xref ref-type="bibr" rid="ref71">71</xref>], whereas Nomura et al [<xref ref-type="bibr" rid="ref72">72</xref>] recruited participants from community clinics or centers.</p>
          <p>One trial delivered the intervention through 4 individually tailored sessions at the clinic [<xref ref-type="bibr" rid="ref31">31</xref>], whereas participants were offered 5 internet-based video counseling calls in another study [<xref ref-type="bibr" rid="ref72">72</xref>]. In 2 studies, participants received up to 8 individual video counseling calls at home [<xref ref-type="bibr" rid="ref70">70</xref>,<xref ref-type="bibr" rid="ref71">71</xref>]. Participants from the rural US study also received written materials on smoking cessation and pharmacotherapy [<xref ref-type="bibr" rid="ref31">31</xref>], whereas studies with Korean-American women and women living with HIV offered nicotine patches to their participants [<xref ref-type="bibr" rid="ref70">70</xref>,<xref ref-type="bibr" rid="ref71">71</xref>]. Participants were followed-up at 3, 6, and 12 months for 1 study [<xref ref-type="bibr" rid="ref31">31</xref>] and at the end of the intervention and at 3 and 6 months for another study [<xref ref-type="bibr" rid="ref71">71</xref>]. In the study with Korean-American women, participants were followed-up for 3 months [<xref ref-type="bibr" rid="ref70">70</xref>], and in the study conducted in Japan, participants were followed-up at 3 and 6 months [<xref ref-type="bibr" rid="ref72">72</xref>].</p>
          <p>Three studies reported prolonged abstinence, 1 at 3 months [<xref ref-type="bibr" rid="ref70">70</xref>], 1 at 6 months [<xref ref-type="bibr" rid="ref71">71</xref>], and 1 at 12 months [<xref ref-type="bibr" rid="ref31">31</xref>]. One study reported continuous abstinence between 9 and 12 weeks and 9 and 24 weeks [<xref ref-type="bibr" rid="ref72">72</xref>]. Three studies reported 7-day point prevalence abstinence outcomes at 1, 2, and 3 months [<xref ref-type="bibr" rid="ref70">70</xref>]; at the end of the intervention; at 3 and 6 months [<xref ref-type="bibr" rid="ref71">71</xref>]; and at 12 months [<xref ref-type="bibr" rid="ref31">31</xref>]. Only the rural US study reported provider costs for real-time video counseling and telephone counseling interventions [<xref ref-type="bibr" rid="ref31">31</xref>].</p>
        </sec>
        <sec>
          <title>Alcohol Use</title>
          <p><xref ref-type="supplementary-material" rid="app2">Multimedia Appendix 2</xref> [<xref ref-type="bibr" rid="ref73">73</xref>-<xref ref-type="bibr" rid="ref75">75</xref>] provides a detailed description of the study characteristics. One study was conducted in Denmark [<xref ref-type="bibr" rid="ref73">73</xref>] and the other 2 studies were conducted in the United States [<xref ref-type="bibr" rid="ref74">74</xref>,<xref ref-type="bibr" rid="ref75">75</xref>]. Participants were recruited from public outpatient alcohol clinics [<xref ref-type="bibr" rid="ref73">73</xref>], a web-based research participation system for undergraduate students [<xref ref-type="bibr" rid="ref75">75</xref>], and community supervision offices for people with substance abuse [<xref ref-type="bibr" rid="ref74">74</xref>]. One study included a clinical population with an alcohol dependence syndrome [<xref ref-type="bibr" rid="ref73">73</xref>], whereas the other 2 studies were conducted with nonclinical populations [<xref ref-type="bibr" rid="ref74">74</xref>,<xref ref-type="bibr" rid="ref75">75</xref>]. The sample sizes were 51 [<xref ref-type="bibr" rid="ref75">75</xref>], 71 [<xref ref-type="bibr" rid="ref73">73</xref>], and 127 [<xref ref-type="bibr" rid="ref74">74</xref>] across the studies. The proportion of men was high in 2 studies, specifically 73% (52/71) [<xref ref-type="bibr" rid="ref73">73</xref>] and 81.1% (103/127) [<xref ref-type="bibr" rid="ref74">74</xref>], whereas the majority were women (60.8%) in 1 study [<xref ref-type="bibr" rid="ref75">75</xref>]. The mean age was 19 (SD not reported) [<xref ref-type="bibr" rid="ref75">75</xref>] and 47 years (SD 12.8) [<xref ref-type="bibr" rid="ref73">73</xref>], with a median age of 30.5 years [<xref ref-type="bibr" rid="ref74">74</xref>]. The participation rate was 63% [<xref ref-type="bibr" rid="ref73">73</xref>] and 73% [<xref ref-type="bibr" rid="ref74">74</xref>] across 2 studies and unclear in 1 study [<xref ref-type="bibr" rid="ref75">75</xref>]. One trial compared video counseling (telehealth) with face-to-face treatment only [<xref ref-type="bibr" rid="ref75">75</xref>]. The other 2 trials compared individual video conferencing plus face-to-face support (treatment as usual) with face-to-face only support (treatment as usual) [<xref ref-type="bibr" rid="ref73">73</xref>,<xref ref-type="bibr" rid="ref74">74</xref>].</p>
          <p>In 1 study, participants received up to 5 sessions with the therapist via videoconference and were followed-up at 3 months [<xref ref-type="bibr" rid="ref74">74</xref>], whereas another study offered between 1 and 3 sessions a week at the initial stages, followed by 1 session every other week for about 7 months, and participants were followed-up until 12 months [<xref ref-type="bibr" rid="ref73">73</xref>]. In the third study, participants received only 2 sessions and were followed-up at 1, 2, and 3 months [<xref ref-type="bibr" rid="ref75">75</xref>].</p>
          <p>Alcohol consumption was measured at 3, 6, and 12 months in 1 study [<xref ref-type="bibr" rid="ref73">73</xref>], at 3 months in another study [<xref ref-type="bibr" rid="ref74">74</xref>], and at 1, 2, and 3 months in the third study [<xref ref-type="bibr" rid="ref75">75</xref>]. The costs of the video intervention and face-to-face support (treatment as usual) were not reported in any of these 3 studies [<xref ref-type="bibr" rid="ref73">73</xref>-<xref ref-type="bibr" rid="ref75">75</xref>].</p>
        </sec>
        <sec>
          <title>Physical Activity</title>
          <p>Three trials examined the effectiveness of individual video counseling to increase physical activity. The trials were conducted in Australia [<xref ref-type="bibr" rid="ref76">76</xref>], the United States [<xref ref-type="bibr" rid="ref77">77</xref>], and Canada [<xref ref-type="bibr" rid="ref78">78</xref>]. Participants were recruited from print and web advertising in 1 study [<xref ref-type="bibr" rid="ref76">76</xref>], whereas in the other 2 studies, participants were recruited from their primary care provider [<xref ref-type="bibr" rid="ref77">77</xref>] or from outpatient rehabilitation hospitals in Montreal, a local adapted fitness center, an organization representing persons with spinal cord injury (SCI), pre-existing databases of previous research participants, and social media platforms [<xref ref-type="bibr" rid="ref78">78</xref>]. Two physical activity trials were conducted with clinical populations, specifically people with paraplegia [<xref ref-type="bibr" rid="ref78">78</xref>] and people with diabetes [<xref ref-type="bibr" rid="ref77">77</xref>], whereas 1 study was conducted with a nonclinical population [<xref ref-type="bibr" rid="ref76">76</xref>]. The sample sizes across the 3 studies were 24 [<xref ref-type="bibr" rid="ref78">78</xref>], 154 [<xref ref-type="bibr" rid="ref76">76</xref>], and 1650 participants [<xref ref-type="bibr" rid="ref77">77</xref>]. In 2 trials, most participants were female (117/154, 76.0% [<xref ref-type="bibr" rid="ref76">76</xref>] and 1037/1650, 62.84% [<xref ref-type="bibr" rid="ref77">77</xref>]), whereas in the third study, the majority were male 73% (16/24) [<xref ref-type="bibr" rid="ref78">78</xref>]. The average BMI was 31 kg/m<sup>2</sup> [<xref ref-type="bibr" rid="ref76">76</xref>] and 32 kg/m<sup>2</sup> [<xref ref-type="bibr" rid="ref77">77</xref>] in 2 studies, and BMI was not reported in the Canadian study [<xref ref-type="bibr" rid="ref78">78</xref>]. Across the studies, the mean age ranged from 51.64 (SD 12.3) [<xref ref-type="bibr" rid="ref78">78</xref>] to 70.9 (SD 6.63) years [<xref ref-type="bibr" rid="ref77">77</xref>]. One trial compared real-time video counseling plus computer-tailored advice with computer-tailored web-based physical activity intervention only (advice tailored to an individual with graphs and text) and to a waitlist control group [<xref ref-type="bibr" rid="ref76">76</xref>]. The intervention participants in this trial received tailored physical activity advice plus video counseling every 2 weeks for 8 weeks (“My Activity Coach”) [<xref ref-type="bibr" rid="ref76">76</xref>]. These were four 10-min coaching sessions with a behavioral expert using a web-based video-calling program (Skype) compared with computer-tailored physical activity advice only and a waitlist control. Participants were followed-up at week 9 and at 6 months [<xref ref-type="bibr" rid="ref76">76</xref>]. In the second study [<xref ref-type="bibr" rid="ref77">77</xref>], the intervention comprised video counseling (home video calls) with a diabetes educator conducted every 4 to 6 weeks for self-management, which was compared with face-to-face care (usual clinic-based care), and participants were followed-up for 5 years [<xref ref-type="bibr" rid="ref77">77</xref>]. The third trial compared video counseling (intervention) versus regular routine (control) in adults with SCI in Canada [<xref ref-type="bibr" rid="ref78">78</xref>]. The intervention comprised 1 leisure time physical activity (LTPA) counseling session per week for 8 weeks, resulting in a total of 8 counseling sessions [<xref ref-type="bibr" rid="ref78">78</xref>]. Participants were then followed-up at weeks 6 and 10 [<xref ref-type="bibr" rid="ref78">78</xref>].</p>
          <p>One trial assessed physical activity in minutes per week at week 9 and 6 months [<xref ref-type="bibr" rid="ref76">76</xref>], another assessed the rate of decline in physical activity in older participants over a 5-year period [<xref ref-type="bibr" rid="ref77">77</xref>], and the third trial assessed total LTPA at 6 and 10 weeks [<xref ref-type="bibr" rid="ref78">78</xref>]. One trial reported a retention rate of 92% at 10 weeks [<xref ref-type="bibr" rid="ref78">78</xref>], and 2 trials reported retention rates of &#60;50% [<xref ref-type="bibr" rid="ref76">76</xref>,<xref ref-type="bibr" rid="ref77">77</xref>]. No cost information was provided for any of the studies. <xref ref-type="supplementary-material" rid="app3">Multimedia Appendix 3</xref> [<xref ref-type="bibr" rid="ref76">76</xref>-<xref ref-type="bibr" rid="ref78">78</xref>] provides a detailed description of the study characteristics.</p>
        </sec>
        <sec>
          <title>Obesity</title>
          <p><xref ref-type="supplementary-material" rid="app4">Multimedia Appendix 4</xref> [<xref ref-type="bibr" rid="ref79">79</xref>-<xref ref-type="bibr" rid="ref81">81</xref>] provides a description of the study characteristics examining the effectiveness of video counseling on obesity. Three trials [<xref ref-type="bibr" rid="ref79">79</xref>-<xref ref-type="bibr" rid="ref81">81</xref>] used individually delivered real-time video counseling to target obesity. The trials targeted clinical populations with lifestyle conditions such as diabetes [<xref ref-type="bibr" rid="ref79">79</xref>,<xref ref-type="bibr" rid="ref80">80</xref>], hypertension [<xref ref-type="bibr" rid="ref80">80</xref>], and overweight or obesity (BMI&#62;25 kg/m<sup>2</sup>) [<xref ref-type="bibr" rid="ref79">79</xref>-<xref ref-type="bibr" rid="ref81">81</xref>]. One study was conducted in Japan [<xref ref-type="bibr" rid="ref80">80</xref>], another study in Denmark [<xref ref-type="bibr" rid="ref79">79</xref>], and the third in the United States [<xref ref-type="bibr" rid="ref81">81</xref>]. In 1 study, the participants were recruited through telephone calls from outpatient departments [<xref ref-type="bibr" rid="ref79">79</xref>] and in another study via community advertisements [<xref ref-type="bibr" rid="ref80">80</xref>], whereas it was unclear how participants were recruited in the third study [<xref ref-type="bibr" rid="ref81">81</xref>]. The sample sizes were 30 [<xref ref-type="bibr" rid="ref81">81</xref>], 68 [<xref ref-type="bibr" rid="ref80">80</xref>], and 165 [<xref ref-type="bibr" rid="ref79">79</xref>]. The mean age was 66 years (SD 1.7) [<xref ref-type="bibr" rid="ref80">80</xref>] and 58 years (SD 9.3) [<xref ref-type="bibr" rid="ref79">79</xref>] in 2 studies and ranged from 42.2 to 44.5 years across the 3 groups in the third study [<xref ref-type="bibr" rid="ref81">81</xref>]. The majority of participants were male 63.8% (106/166) in 1 trial [<xref ref-type="bibr" rid="ref79">79</xref>] and female 65% (44/68) in another trial [<xref ref-type="bibr" rid="ref80">80</xref>], whereas the gender distribution was not reported in the third trial [<xref ref-type="bibr" rid="ref81">81</xref>]. The trials reported BMI and physical activity outcomes at 3 months [<xref ref-type="bibr" rid="ref80">80</xref>], BMI and waist to hip ratio at 8 and 14 months [<xref ref-type="bibr" rid="ref79">79</xref>], and physical activity and body weight loss over 12 weeks [<xref ref-type="bibr" rid="ref81">81</xref>].</p>
          <p>The video counseling intervention was compared with either individualized documented reports (individualized written reports at 3 time points addressing lifestyle modifications) [<xref ref-type="bibr" rid="ref80">80</xref>] or usual care (face-to-face) [<xref ref-type="bibr" rid="ref79">79</xref>] or face-to-face or a control group that received no feedback from mobile health devices and no health coaching sessions [<xref ref-type="bibr" rid="ref81">81</xref>]. In 1 study, real-time video consultations were delivered 3 times in 3 months [<xref ref-type="bibr" rid="ref80">80</xref>]. In another study, they used video add-ons in usual clinic-based care (every 3-6 months) with a health care center nurse via a tablet for 32 weeks [<xref ref-type="bibr" rid="ref79">79</xref>]. In the third study, the video counseling intervention participants received health coaching educational materials and weekly individualized videoconferencing by a multidisciplinary team (registered dietitian, exercise physiologist, and medical doctor) based on data uploaded over the 12-week intervention [<xref ref-type="bibr" rid="ref81">81</xref>]. None of the trials provided any information on the cost of the interventions.</p>
        </sec>
      </sec>
      <sec>
        <title>Effectiveness of Real-Time Video Counseling on Smoking Cessation</title>
        <p>In the nonclinical populations [<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref70">70</xref>,<xref ref-type="bibr" rid="ref72">72</xref>], Richter et al found no significant difference between video counseling and telephone counseling for self-reported 7-day point prevalence abstinence at 3 months and 6 months and reported no significant difference between video counseling (9.8%) and telephone counseling (12%) in biochemically verified 7-day point prevalence abstinence and prolonged abstinence (video 8.1% and telephone 7.6%) at 12 months [<xref ref-type="bibr" rid="ref31">31</xref>]. Kim et al [<xref ref-type="bibr" rid="ref70">70</xref>] reported no significant difference between biochemically validated 7-day point prevalence abstinence in the video counseling arm (33.3%) compared with the telephone counseling arm (28%) at 3 months. Prolonged abstinence also did not differ significantly between the video counseling arm (29.2%) and the telephone counseling arm (28%) [<xref ref-type="bibr" rid="ref70">70</xref>]. Nomura et al [<xref ref-type="bibr" rid="ref72">72</xref>] found no significant difference between video counseling and face-to-face sessions for biochemically validated continuous abstinence rate between weeks 9 to 12 (video 81.0%; face-to-face 78.9%) and weeks 9 to 24 (video 74.1%; face-to-face 71.9%).</p>
        <p>In a study conducted with women living with HIV, a clinical population, the video counseling group was significantly more likely than the telephone counseling group to achieve biochemically verified point prevalence abstinence at 3 months (video 33.3%; telephone 4.8%) and 6 months postquitting (video 38.1%; telephone 4.8%) [<xref ref-type="bibr" rid="ref71">71</xref>]. This study also found that those in the video counseling group were significantly more likely than the telephone counseling group to achieve a 6-month prolonged abstinence (video 33.3%; telephone 4.8%) [<xref ref-type="bibr" rid="ref71">71</xref>].</p>
      </sec>
      <sec>
        <title>Effectiveness of Real-Time Video Counseling on Alcohol Use</title>
        <p>Two studies were conducted in a nonclinical population [<xref ref-type="bibr" rid="ref74">74</xref>,<xref ref-type="bibr" rid="ref75">75</xref>]. In 1 study [<xref ref-type="bibr" rid="ref74">74</xref>], compared with usual care (social service clinician) only, the real-time video communication group did not significantly differ on any alcohol consumption, days of drinking, drinks per week, and days experiencing alcohol problems at 3 months. In the second study, there was no significant difference in the change in Alcohol Use Disorders Identification Test scores between the video support group and the face-to-face support group from baseline to 1 month posttreatment and 1 to 3 months posttreatment [<xref ref-type="bibr" rid="ref75">75</xref>]. Similarly, there was no significant difference in Rutgers Alcohol Problem Index (RAPI) scores between the groups at 1-month follow-up and the decrease in RAPI scores from baseline to 1 month and between 1- and 3-month follow-ups [<xref ref-type="bibr" rid="ref75">75</xref>].</p>
        <p>Only a single study was conducted in a clinical population (alcohol dependent) [<xref ref-type="bibr" rid="ref73">73</xref>]. Tarp et al [<xref ref-type="bibr" rid="ref73">73</xref>] found no significant difference between video counseling options and usual face-to-face care in the change from baseline to 12 months in the number of days of alcohol consumption in the past month and days of excessive alcohol consumption in the past month.</p>
      </sec>
      <sec>
        <title>Effectiveness of Real-Time Video Counseling on Physical Activity</title>
        <p>One study for physical activity was conducted among a nonclinical population [<xref ref-type="bibr" rid="ref76">76</xref>]. In this study, there was a significant change in physical activity (minutes per week) from baseline to week 9 between the tailoring and video-coaching intervention for physical activity and the control group, but there was no significant change between the tailoring and video-coaching intervention and the tailoring-only intervention [<xref ref-type="bibr" rid="ref76">76</xref>]. From baseline to 6 months, the change in physical activity (minutes per week) did not significantly differ between the tailoring plus video-coaching intervention and either of the other groups [<xref ref-type="bibr" rid="ref76">76</xref>].</p>
        <p>Two of the physical activity studies were conducted among a clinical population [<xref ref-type="bibr" rid="ref77">77</xref>,<xref ref-type="bibr" rid="ref78">78</xref>].</p>
        <p>In the study by Weinstock et al [<xref ref-type="bibr" rid="ref77">77</xref>] among people with diabetes, there was a significantly lower rate of decline in physical activity over time in the video counseling group than in the usual care group. In the second study among people with paraplegia, Chemtob et al found that compared with the control group, the video counseling group reported greater total minutes of LTPA at 6 weeks (Hedge g=0.87) and 10 weeks (Hedge g=0.85) [<xref ref-type="bibr" rid="ref78">78</xref>]. For moderate and vigorous physical activity, moderate effect sizes were found at 6 weeks (Hedge g=0.52) and small effect sizes were found at 10 weeks (Hedge g=0.34) favoring the video counseling group over the control group [<xref ref-type="bibr" rid="ref78">78</xref>].</p>
      </sec>
      <sec>
        <title>Effectiveness of Real-Time Video Counseling on Obesity</title>
        <p>All studies examining the effectiveness of real-time video counseling on obesity were conducted with clinical populations [<xref ref-type="bibr" rid="ref79">79</xref>-<xref ref-type="bibr" rid="ref81">81</xref>]. One study compared video counseling with usual care and found no changes in BMI or waist to hip ratio [<xref ref-type="bibr" rid="ref79">79</xref>]. The second study found a significant change in BMI from preintervention to postintervention (3 months) between the video counseling intervention and the individualized monthly document reports group but no significant change between the groups in average steps per day from preintervention to postintervention [<xref ref-type="bibr" rid="ref80">80</xref>]. The third study by Johnson et al [<xref ref-type="bibr" rid="ref81">81</xref>] found that the video counseling group achieved significantly greater weight loss from baseline to 12 weeks than the in-person group and the control group. This study also reported that the video counseling group had significantly higher steps per day than the in-person group at week 4 and the control group at weeks 6, 8, 9, and 11 [<xref ref-type="bibr" rid="ref81">81</xref>].</p>
      </sec>
      <sec>
        <title>Satisfaction With Real-Time Video Counseling for Smoking Cessation</title>
        <p>Two studies [<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref71">71</xref>] compared the satisfaction of real-time video counseling for smoking cessation with telephone counseling. In 1 study with a nonclinical population [<xref ref-type="bibr" rid="ref31">31</xref>], those in the video counseling group (97%) were significantly more likely to recommend the program to family and friends than those in the telephone counseling arm (91.9%), but no between-group differences were found for other satisfaction measures. In the other study with a clinical population, there was no significant difference in mean satisfaction scores between the video counseling and the telephone counseling groups [<xref ref-type="bibr" rid="ref71">71</xref>].</p>
      </sec>
      <sec>
        <title>Satisfaction With Real-Time Video Counseling for Alcohol Use</title>
        <p>Of the 3 [<xref ref-type="bibr" rid="ref73">73</xref>-<xref ref-type="bibr" rid="ref75">75</xref>] studies on alcohol consumption, 1 study [<xref ref-type="bibr" rid="ref75">75</xref>] assessed satisfaction. This study compared treatment satisfaction between the video counseling group and the face-to-face support group in a nonclinical population and found no significant difference between the 2 groups for client satisfaction questionnaire scores at either session 1 or session 2 [<xref ref-type="bibr" rid="ref75">75</xref>].</p>
      </sec>
      <sec>
        <title>Satisfaction With Real-Time Video Counseling for Physical Activity</title>
        <p>One study on physical activity in a nonclinical population [<xref ref-type="bibr" rid="ref76">76</xref>] reported on the satisfaction between tailoring and video coaching compared with tailoring-only. Alley et al [<xref ref-type="bibr" rid="ref76">76</xref>] found no significant difference between these groups on program satisfaction scores.</p>
      </sec>
      <sec>
        <title>Satisfaction With Real-Time Video Counseling for Obesity</title>
        <p>All 3 studies conducted with clinical populations [<xref ref-type="bibr" rid="ref79">79</xref>-<xref ref-type="bibr" rid="ref81">81</xref>] that focused on obesity did not assess satisfaction with video counseling compared with the comparator used.</p>
      </sec>
      <sec>
        <title>Methodological Quality Assessment for Real-Time Video Counseling Studies</title>
        <p><xref ref-type="table" rid="table1">Table 1</xref> outlines the methodological quality ratings for each study across the 6 components (selection bias, study design, confounders, blinding, data collection methods, withdrawals, and dropouts) and the overall global rating. In terms of the global rating, only 1 study was rated as moderate (a physical activity trial) [<xref ref-type="bibr" rid="ref77">77</xref>], whereas 12 studies had a weak global rating (4 smoking cessation trials [<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref70">70</xref>-<xref ref-type="bibr" rid="ref72">72</xref>], 3 alcohol trials [<xref ref-type="bibr" rid="ref73">73</xref>-<xref ref-type="bibr" rid="ref75">75</xref>], 2 physical activity trials [<xref ref-type="bibr" rid="ref76">76</xref>,<xref ref-type="bibr" rid="ref78">78</xref>], and 3 obesity trials [<xref ref-type="bibr" rid="ref79">79</xref>-<xref ref-type="bibr" rid="ref81">81</xref>]).</p>
        <table-wrap position="float" id="table1">
          <label>Table 1</label>
          <caption>
            <p>Methodological quality assessment of eligible studies.</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="30"/>
            <col width="140"/>
            <col width="0"/>
            <col width="110"/>
            <col width="0"/>
            <col width="110"/>
            <col width="0"/>
            <col width="120"/>
            <col width="0"/>
            <col width="110"/>
            <col width="0"/>
            <col width="130"/>
            <col width="0"/>
            <col width="140"/>
            <col width="0"/>
            <col width="110"/>
            <thead>
              <tr valign="top">
                <td colspan="2">Study</td>
                <td colspan="2">Selection bias</td>
                <td colspan="2">Study design</td>
                <td colspan="2">Confounders</td>
                <td colspan="2">Blinding</td>
                <td colspan="2">Data collection methods</td>
                <td colspan="2">Withdrawals and dropouts</td>
                <td colspan="2">Global rating</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td colspan="16">
                  <bold>Smoking</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td colspan="2">Kim et al [<xref ref-type="bibr" rid="ref70">70</xref>]</td>
                <td colspan="2">Weak</td>
                <td colspan="2">Strong</td>
                <td colspan="2">Weak</td>
                <td colspan="2">Weak</td>
                <td colspan="2">Strong</td>
                <td colspan="2">Moderate</td>
                <td>Weak</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td colspan="2">Kim et al [<xref ref-type="bibr" rid="ref71">71</xref>]</td>
                <td colspan="2">Weak</td>
                <td colspan="2">Strong</td>
                <td colspan="2">Weak</td>
                <td colspan="2">Weak</td>
                <td colspan="2">Strong</td>
                <td colspan="2">Weak</td>
                <td>Weak</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td colspan="2">Nomura et al [<xref ref-type="bibr" rid="ref72">72</xref>]</td>
                <td colspan="2">Weak</td>
                <td colspan="2">Strong</td>
                <td colspan="2">Strong</td>
                <td colspan="2">Weak</td>
                <td colspan="2">Strong</td>
                <td colspan="2">Strong</td>
                <td>Weak</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td colspan="2">Richter et al [<xref ref-type="bibr" rid="ref31">31</xref>]</td>
                <td colspan="2">Weak</td>
                <td colspan="2">Strong</td>
                <td colspan="2">Strong</td>
                <td colspan="2">Weak</td>
                <td colspan="2">Strong</td>
                <td colspan="2">Strong</td>
                <td>Weak</td>
              </tr>
              <tr valign="top">
                <td colspan="16">
                  <bold>Alcohol</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td colspan="2">King et al [<xref ref-type="bibr" rid="ref75">75</xref>]</td>
                <td colspan="2">Weak</td>
                <td colspan="2">Strong</td>
                <td colspan="2">Moderate</td>
                <td colspan="2">Weak</td>
                <td colspan="2">Strong</td>
                <td colspan="2">Weak</td>
                <td>Weak</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td colspan="2">Staton-Tindall et al [<xref ref-type="bibr" rid="ref74">74</xref>]</td>
                <td colspan="2">Moderate</td>
                <td colspan="2">Strong</td>
                <td colspan="2">Weak</td>
                <td colspan="2">Weak</td>
                <td colspan="2">Weak</td>
                <td colspan="2">Strong</td>
                <td>Weak</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td colspan="2">Tarp et al [<xref ref-type="bibr" rid="ref73">73</xref>]</td>
                <td colspan="2">Weak</td>
                <td colspan="2">Strong</td>
                <td colspan="2">Strong</td>
                <td colspan="2">Weak</td>
                <td colspan="2">Strong</td>
                <td colspan="2">Moderate</td>
                <td>Weak</td>
              </tr>
              <tr valign="top">
                <td colspan="16">
                  <bold>Physical activity</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td colspan="2">Alley et al [<xref ref-type="bibr" rid="ref76">76</xref>]</td>
                <td colspan="2">Weak</td>
                <td colspan="2">Strong</td>
                <td colspan="2">Weak</td>
                <td colspan="2">Weak</td>
                <td colspan="2">Strong</td>
                <td colspan="2">Weak</td>
                <td>Weak</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td colspan="2">Chemtob et al [<xref ref-type="bibr" rid="ref78">78</xref>]</td>
                <td colspan="2">Weak</td>
                <td colspan="2">Strong</td>
                <td colspan="2">Weak</td>
                <td colspan="2">Moderate</td>
                <td colspan="2">Strong</td>
                <td colspan="2">Strong</td>
                <td>Weak</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td colspan="2">Weinstock et al [<xref ref-type="bibr" rid="ref77">77</xref>]</td>
                <td colspan="2">Weak</td>
                <td colspan="2">Strong</td>
                <td colspan="2">Strong</td>
                <td colspan="2">Moderate</td>
                <td colspan="2">Moderate</td>
                <td colspan="2">Strong</td>
                <td>Moderate</td>
              </tr>
              <tr valign="top">
                <td colspan="16">
                  <bold>Obesity</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td colspan="2">Hansen et al [<xref ref-type="bibr" rid="ref79">79</xref>]</td>
                <td colspan="2">Weak</td>
                <td colspan="2">Strong</td>
                <td colspan="2">Strong</td>
                <td colspan="2">Weak</td>
                <td colspan="2">Strong</td>
                <td colspan="2">Strong</td>
                <td>Weak</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td colspan="2">Homma et al [<xref ref-type="bibr" rid="ref80">80</xref>]</td>
                <td colspan="2">Weak</td>
                <td colspan="2">Strong</td>
                <td colspan="2">Weak</td>
                <td colspan="2">Weak</td>
                <td colspan="2">Strong</td>
                <td colspan="2">Strong</td>
                <td>Weak</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td colspan="2">Johnson et al [<xref ref-type="bibr" rid="ref81">81</xref>]</td>
                <td colspan="2">Weak</td>
                <td colspan="2">Strong</td>
                <td colspan="2">Strong</td>
                <td colspan="2">Weak</td>
                <td colspan="2">Strong</td>
                <td colspan="2">Strong</td>
                <td>Weak</td>
              </tr>
            </tbody>
          </table>
        </table-wrap>
        <p>Most studies (n=12) were rated as weak for selection bias because the participation rate was &#60;60% or unclear [<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref70">70</xref>-<xref ref-type="bibr" rid="ref73">73</xref>,<xref ref-type="bibr" rid="ref75">75</xref>-<xref ref-type="bibr" rid="ref81">81</xref>]. Blinding of either the outcome assessor or the participant was also another component where most (n=11) studies were rated as weak [<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref70">70</xref>-<xref ref-type="bibr" rid="ref76">76</xref>,<xref ref-type="bibr" rid="ref79">79</xref>-<xref ref-type="bibr" rid="ref81">81</xref>]. Regarding confounders, 6 studies had a weak rating because &#60;60% of the potential confounders were controlled for [<xref ref-type="bibr" rid="ref80">80</xref>] or it was unclear whether potential confounders were controlled for [<xref ref-type="bibr" rid="ref70">70</xref>,<xref ref-type="bibr" rid="ref71">71</xref>,<xref ref-type="bibr" rid="ref74">74</xref>,<xref ref-type="bibr" rid="ref76">76</xref>,<xref ref-type="bibr" rid="ref78">78</xref>]. Data collection was only weak in a single study [<xref ref-type="bibr" rid="ref74">74</xref>] because it was unclear whether the tools used were reliable. Three studies were rated as weak in relation to withdrawals and dropouts because they reported low overall retention rates of 30% [<xref ref-type="bibr" rid="ref75">75</xref>] and 38% [<xref ref-type="bibr" rid="ref76">76</xref>] or low retention for one arm of the study (48%) [<xref ref-type="bibr" rid="ref71">71</xref>].</p>
      </sec>
    </sec>
    <sec sec-type="discussion">
      <title>Discussion</title>
      <sec>
        <title>Principal Findings</title>
        <p>This is the first review to examine the effectiveness of individual real-time video counseling on smoking, nutrition, alcohol consumption, physical activity, and obesity. This review focused on real-time video communication technology, an emerging intervention delivery mode. The overall results suggest that video counseling is neither more nor less effective in modifying smoking and alcohol consumption but may have particular benefits for addressing physical inactivity and obesity. Given that the effectiveness of video counseling was similar to conventional methods used to treat smoking and alcohol consumption and that many individuals with nicotine dependence or alcohol dependence may not join and complete conventional treatment [<xref ref-type="bibr" rid="ref82">82</xref>,<xref ref-type="bibr" rid="ref83">83</xref>], video counseling provides another option to engage people with nicotine dependence or alcohol dependence who are unlikely to use conventional treatment or drop out of such support. If real-time video counseling is at least equally effective to existing treatments such as face-to-face interventions, then the smoking, nutrition, alcohol consumption, physical activity, and obesity program providers should consider including video counseling as an additional option into their services. The importance of a variety of delivery modes has been demonstrated during the COVID-19 pandemic, where access to face-to-face services has been restricted, whereas in contrast, real-time video counseling for risks for smoking, nutrition, alcohol consumption, physical activity, and obesity is sustainable in this context. The cost of video counseling compared with other modes of delivery is difficult to determine because it was reported in only 1 smoking cessation study [<xref ref-type="bibr" rid="ref31">31</xref>], which required participants to travel to the clinic to receive video sessions (instead of receiving video sessions at home).</p>
        <p>Of the 4 studies that examined the effectiveness of video counseling on smoking cessation [<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref70">70</xref>-<xref ref-type="bibr" rid="ref72">72</xref>], only 1 study reported a significant difference between video counseling and telephone counseling at the 3- and 6-month follow-up, which favored the video counseling group [<xref ref-type="bibr" rid="ref71">71</xref>]. All studies that focused on smoking cessation were comparative effectiveness trials, and there is currently no evidence available on the effectiveness of real-time video counseling compared with a no-intervention or minimal support (eg, written self-help materials) control group for smoking cessation. The global methodological quality rating of the 4 studies that assessed the effectiveness of real-time video counseling for smoking cessation was weak, suggesting that the methodological rigor of the evidence needs to be improved, particularly in relation to blinding. However, given the nature of trials that examine the effectiveness of real-time video counseling, blinding would be difficult [<xref ref-type="bibr" rid="ref84">84</xref>]. Additionally, 3 of the 4 studies were conducted in specific populations, such as Korean-American women [<xref ref-type="bibr" rid="ref70">70</xref>], women living with HIV [<xref ref-type="bibr" rid="ref71">71</xref>], and rural smokers [<xref ref-type="bibr" rid="ref31">31</xref>], hence limiting the generalizability of the findings. Given that quitlines provide telephone counseling as part of their standard practices [<xref ref-type="bibr" rid="ref85">85</xref>,<xref ref-type="bibr" rid="ref86">86</xref>], and 2 studies report no differences between telephone counseling and video counseling for smoking cessation [<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref70">70</xref>] whereas 1 study suggests that video counseling for smoking cessation is superior to telephone counseling [<xref ref-type="bibr" rid="ref71">71</xref>], quitline providers could consider expanding their routine services to include real-time video counseling.</p>
        <p>The evidence in 3 studies indicated that there was no significant difference between real-time video counseling and face-to-face counseling (usual care) for reducing alcohol consumption [<xref ref-type="bibr" rid="ref73">73</xref>-<xref ref-type="bibr" rid="ref75">75</xref>]. All studies had a weak global rating with small sample sizes and low retention rates, which resulted in limited power to detect any differences. Moreover, one of the studies included a largely white population (98%) [<xref ref-type="bibr" rid="ref74">74</xref>] and therefore may have limited generalizability with respect to other cultures and populations, such as those in low- and middle-income countries. Nonetheless, given that real-time video counseling overcomes barriers associated with face-to-face treatment for alcohol consumption such as time and distance [<xref ref-type="bibr" rid="ref87">87</xref>], and no differences were found between face-to-face treatment (usual care) and video consultations [<xref ref-type="bibr" rid="ref73">73</xref>-<xref ref-type="bibr" rid="ref75">75</xref>], service providers could consider offering real-time video counseling as an additional option for modifying alcohol consumption.</p>
        <p>Real-time video counseling was found to significantly increase physical activity when compared with usual care at week 9 [<xref ref-type="bibr" rid="ref76">76</xref>] and after 5 years [<xref ref-type="bibr" rid="ref77">77</xref>]. However, given the limitations in methodological quality and the paucity of research in this field, further randomized trials examining the effectiveness of real-time video counseling on physical activity are warranted. Given that the existing studies focused on high-income countries, included only obese or diabetic populations, and included participants who were predominantly women, white, and highly educated, the generalizability of the findings to other populations may be limited. Despite the limited evidence, the existing research suggests that real-time video counseling is more effective than usual care for improving physical activity. Therefore, physical activity service providers could consider offering real-time video counseling as part of their routine practice.</p>
        <p>Two studies that focused on obesity reported a significant change in BMI from preintervention to 3 months between the video counseling intervention and the individualized monthly document reports group [<xref ref-type="bibr" rid="ref80">80</xref>], and the video counseling group achieved significantly greater weight loss from baseline to 12 weeks than the in-person group and control group [<xref ref-type="bibr" rid="ref81">81</xref>]. Only 1 study found no changes in BMI and waist to hip ratio between the video add-on group and the face-to-face treatment group (usual clinic-based care) [<xref ref-type="bibr" rid="ref79">79</xref>]. Two of the 3 studies that focused on obesity also reported physical activity outcomes. There was a significant difference for 1 study reporting on increasing steps per day for video counseling compared with the control group that favored the video counseling group [<xref ref-type="bibr" rid="ref81">81</xref>], whereas 1 study found no difference in change in average steps per day between video counseling and individualized documented reports [<xref ref-type="bibr" rid="ref80">80</xref>]. All 3 studies were rated as weak for selection bias and therefore were unlikely to be representative of the target population. There is some evidence to suggest that real-time video counseling is effective for obesity. Further randomized trials assessing the effectiveness of real-time video counseling with robust methodological quality on obesity are required.</p>
        <p>It is worth noting that 7 studies [<xref ref-type="bibr" rid="ref71">71</xref>,<xref ref-type="bibr" rid="ref73">73</xref>,<xref ref-type="bibr" rid="ref77">77</xref>-<xref ref-type="bibr" rid="ref81">81</xref>] have focused on clinical populations (1 HIV [smoking trial] [<xref ref-type="bibr" rid="ref71">71</xref>], 3 diabetes [1 physical activity and 2 obesity trials] [<xref ref-type="bibr" rid="ref77">77</xref>,<xref ref-type="bibr" rid="ref79">79</xref>,<xref ref-type="bibr" rid="ref80">80</xref>], 1 alcohol dependence syndrome [alcohol trial] [<xref ref-type="bibr" rid="ref73">73</xref>], 1 paraplegia [physical activity] [<xref ref-type="bibr" rid="ref78">78</xref>], and 3 obesity [obesity trials] [<xref ref-type="bibr" rid="ref79">79</xref>-<xref ref-type="bibr" rid="ref81">81</xref>]). Four of these studies in clinical populations found that video counseling was superior to the comparator [<xref ref-type="bibr" rid="ref71">71</xref>,<xref ref-type="bibr" rid="ref77">77</xref>,<xref ref-type="bibr" rid="ref80">80</xref>,<xref ref-type="bibr" rid="ref81">81</xref>], whereas video counseling was as effective as the comparator in 3 trials [<xref ref-type="bibr" rid="ref73">73</xref>,<xref ref-type="bibr" rid="ref78">78</xref>,<xref ref-type="bibr" rid="ref79">79</xref>]. Six studies [<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref70">70</xref>,<xref ref-type="bibr" rid="ref72">72</xref>,<xref ref-type="bibr" rid="ref74">74</xref>-<xref ref-type="bibr" rid="ref76">76</xref>] focused on nonclinical populations. Five of the studies with nonclinical populations reported video counseling to be as effective as the comparator group [<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref70">70</xref>,<xref ref-type="bibr" rid="ref72">72</xref>,<xref ref-type="bibr" rid="ref74">74</xref>,<xref ref-type="bibr" rid="ref75">75</xref>], whereas video counseling was superior to the comparator in 1 study in the short term but not in the longer term [<xref ref-type="bibr" rid="ref76">76</xref>]. To expand the evidence, future research is needed to examine the effectiveness of real-time video counseling for smoking, nutrition, alcohol consumption, physical activity, and obesity behaviors in both clinical and nonclinical populations.</p>
        <p>Four studies (1 smoking [<xref ref-type="bibr" rid="ref31">31</xref>], 1 alcohol [<xref ref-type="bibr" rid="ref74">74</xref>], and 2 physical activity [<xref ref-type="bibr" rid="ref76">76</xref>,<xref ref-type="bibr" rid="ref77">77</xref>]) were either conducted exclusively in rural areas or rural and/or regional areas were targeted along with urban locations as part of recruitment. One study with rural residents reported no difference between video counseling and telephone counseling for smoking cessation [<xref ref-type="bibr" rid="ref31">31</xref>] and another study found no difference between video counseling and face-to-face support on alcohol consumption [<xref ref-type="bibr" rid="ref74">74</xref>]. In studies that targeted rural and/or regional areas along with urban locations, real-time video counseling was found to significantly increase physical activity compared with usual care at week 9 [<xref ref-type="bibr" rid="ref76">76</xref>] and after 5 years [<xref ref-type="bibr" rid="ref77">77</xref>]. Given that rural populations may face challenges accessing services because of distance, real-time video counseling, which is either as effective or more effective than control or comparator interventions, may overcome barriers to accessing smoking, nutrition, alcohol consumption, physical activity, and obesity services in rural locations.</p>
        <p>Satisfaction with video counseling was compared with a comparator group in 2 smoking trials [<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref71">71</xref>], 1 alcohol trial [<xref ref-type="bibr" rid="ref75">75</xref>], and 1 physical activity trial [<xref ref-type="bibr" rid="ref76">76</xref>]. Three of these 4 studies reported no significant differences between real-time video counseling and the comparator group in terms of satisfaction [<xref ref-type="bibr" rid="ref71">71</xref>,<xref ref-type="bibr" rid="ref75">75</xref>,<xref ref-type="bibr" rid="ref76">76</xref>], whereas 1 smoking cessation trial reported that those in the video counseling group were more likely to recommend the program to family and friends than those in the telephone counseling arm [<xref ref-type="bibr" rid="ref31">31</xref>]. Overall, these results suggest that in terms of satisfaction, those offered real-time video counseling to address smoking, alcohol consumption, and physical activity risks are at least as satisfied with this program as those offered other conventional methods. This provides further support for the potential of real-time video counseling to be integrated into existing preventive care programs.</p>
      </sec>
      <sec>
        <title>Limitations</title>
        <p>Although a comprehensive search strategy was conducted, the studies included were disproportionate across smoking, nutrition, alcohol consumption, physical activity, and obesity outcomes. Namely, there was no intervention targeting nutrition and only 4 studies targeting smoking, 3 studies targeting alcohol consumption, 3 studies targeting physical activity, and 3 studies targeting obesity. The lack of studies limits the conclusions that can be made and highlights the need for more trials assessing the effectiveness of individual, real-time video counseling that target these behaviors. Additionally, some studies that were not published in a peer-reviewed journal or not written in English were excluded, and some studies may have been missed through limitations in the searched databases [<xref ref-type="bibr" rid="ref88">88</xref>]. Another limitation is that all included studies were conducted in high-income countries; therefore, the findings may not be generalizable to populations in developing countries or those with a diverse socioeconomic status and cultural background. Furthermore, more than half of the studies had a sample size of &#60;100 participants [<xref ref-type="bibr" rid="ref70">70</xref>,<xref ref-type="bibr" rid="ref71">71</xref>,<xref ref-type="bibr" rid="ref73">73</xref>,<xref ref-type="bibr" rid="ref75">75</xref>,<xref ref-type="bibr" rid="ref78">78</xref>,<xref ref-type="bibr" rid="ref80">80</xref>,<xref ref-type="bibr" rid="ref81">81</xref>], which may have resulted in inadequate statistical power to detect differences between groups. Additionally, in terms of methodological quality, 12 of the 13 studies had a global rating of weak, with improvements needed particularly for selection bias and blinding. Furthermore, the quality assessment for each study was based on the information reported in the publication by the authors [<xref ref-type="bibr" rid="ref36">36</xref>], which may have had an impact on quality assessment.</p>
        <p>This review highlights the need for more research trials examining the effectiveness of video counseling for health risks for smoking, nutrition, alcohol consumption, physical activity, and obesity. Future research should assess the effectiveness of video counseling for each health risk behavior in various populations (eg, general population, high-risk groups, and minority groups), settings (eg, health care settings, community settings, rural and remote locations), countries (eg, low- and middle-income), and cultures (eg, culturally and linguistically diverse groups, indigenous) to build upon the evidence-base and improve the generalizability of the findings. Studies examining the effectiveness of real-time video counseling for health factors of smoking, nutrition, alcohol consumption, physical activity, and obesity should consider having a larger sample size to increase the power to detect differences between groups, include populations with diverse socioeconomic and cultural backgrounds, and reduce selection bias through random selection and blind assessors and participants where possible. Future research could also examine the effectiveness of real-time video counseling for other behaviors such as sleep, health care seeking behaviors, adherence to treatments, and mental health.</p>
        <p>Such evidence is important for informing the practices of public health prevention programs and health practitioners. Real-time video consultations have been successfully used by health practitioners for various patient-clinician consultations of long-term conditions such as heart failure, depression, schizophrenia, stroke, asthma, spinal cord injury, and chronic pain [<xref ref-type="bibr" rid="ref89">89</xref>]. Similarly, this review suggests that health practitioners could extend the use of real-time video consultations to address the risks of smoking, nutrition, alcohol consumption, physical activity, and obesity with clients. Public health programs such as quitlines and other telephone or face-to-face services that aim to modify the risks of smoking, nutrition, alcohol consumption, physical activity, and obesity could also consider including the option for clients to choose to have support delivered via real-time video consultations. The choice to utilize real-time videoconferencing may be influenced by many factors such as client preference and funding available to providers and conditions of such funding. The use of video communication technology to provide health care services during the COVID-19 pandemic illustrates the sustainability of real-time video counseling for the risks of smoking, nutrition, alcohol consumption, physical activity, and obesity and the accessibility and reach of this intervention.</p>
      </sec>
      <sec>
        <title>Conclusions</title>
        <p>This review focused on effectiveness, costs, and satisfaction, factors that contribute to decision making regarding the mode by which care is delivered to clients. Policy makers and service providers also take into account other factors when making a decision about whether to integrate an intervention into their routine practices, such as feasibility, each from a provider and a client perspective. Further research is required to determine the relative benefits of video counseling in terms of these other policy and practice decision-making factors.</p>
      </sec>
    </sec>
  </body>
  <back>
    <app-group>
      <supplementary-material id="app1">
        <label>Multimedia Appendix 1</label>
        <p>Characteristics of studies examining the effectiveness of video counseling on smoking cessation  .</p>
        <media xlink:href="jmir_v22i9e18621_app1.docx" xlink:title="DOCX File , 18 KB"/>
      </supplementary-material>
      <supplementary-material id="app2">
        <label>Multimedia Appendix 2</label>
        <p>Characteristics of studies examining the effectiveness of video counseling on alcohol consumption.</p>
        <media xlink:href="jmir_v22i9e18621_app2.docx" xlink:title="DOCX File , 17 KB"/>
      </supplementary-material>
      <supplementary-material id="app3">
        <label>Multimedia Appendix 3</label>
        <p>Characteristics of studies examining the effectiveness of video counseling on physical activity.</p>
        <media xlink:href="jmir_v22i9e18621_app3.docx" xlink:title="DOCX File , 17 KB"/>
      </supplementary-material>
      <supplementary-material id="app4">
        <label>Multimedia Appendix 4</label>
        <p>Characteristics of studies examining the effectiveness of video counseling on obesity.</p>
        <media xlink:href="jmir_v22i9e18621_app4.docx" xlink:title="DOCX File , 16 KB"/>
      </supplementary-material>
    </app-group>
    <glossary>
      <title>Abbreviations</title>
      <def-list>
        <def-item>
          <term id="abb1">COM-B</term>
          <def>
            <p>capability, opportunity, motivation, and behavior</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb2">DALY</term>
          <def>
            <p>disability-adjusted life year</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb3">LTPA</term>
          <def>
            <p>leisure time physical activity</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb4">MET</term>
          <def>
            <p>metabolic equivalent</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb5">PRISMA</term>
          <def>
            <p>Preferred Reporting Items for Systematic Reviews and Meta-Analyses</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb6">PROSPERO</term>
          <def>
            <p>Prospective Register of Systematic Reviews</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb7">RAPI</term>
          <def>
            <p>Rutgers Alcohol Problem Index</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb8">SCI</term>
          <def>
            <p>spinal cord injury</p>
          </def>
        </def-item>
      </def-list>
    </glossary>
    <ack>
      <p>The School of Medicine and Public Health at the University of Newcastle, Hunter New England Population Health, and Hunter Medical Research Institute provided infrastructure support. FT was supported by a Cancer Institute New South Wales Early Career Fellowship (15/ECF/1-44) followed by a National Health &#38; Medical Research Council Career Development Fellowship (APP1143269). The sponsors had no role in the study design; in the collection, analyses, and interpretation of data; in the writing of the manuscript; and in the decision to submit the paper for publication.</p>
    </ack>
    <fn-group>
      <fn fn-type="conflict">
        <p>None declared.</p>
      </fn>
    </fn-group>
    <ref-list>
      <ref id="ref1">
        <label>1</label>
        <nlm-citation citation-type="web">
          <article-title>Noncommunicable Diseases</article-title>
          <source>World Health Organisation</source>
          <year>2018</year>
          <access-date>2020-02-24</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.who.int/news-room/fact-sheets/detail/noncommunicable-diseases">https://www.who.int/news-room/fact-sheets/detail/noncommunicable-diseases</ext-link>
            <ext-link ext-link-type="webcite" xlink:href="https://www.who.int/news-room/fact-sheets/detail/noncommunicable-diseases"/>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref2">
        <label>2</label>
        <nlm-citation citation-type="web">
          <article-title>Who Report on the Global Tobacco Epidemic, 2019: Offer Help to Quit Tobacco Use</article-title>
          <source>World Health Organisation</source>
          <year>2019</year>
          <access-date>2020-08-31</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://apps.who.int/iris/bitstream/handle/10665/326043/9789241516204-eng.pdf?ua=1">https://apps.who.int/iris/bitstream/handle/10665/326043/9789241516204-eng.pdf?ua=1</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref3">
        <label>3</label>
        <nlm-citation citation-type="book">
          <person-group person-group-type="author">
            <collab>World Health Organisation</collab>
          </person-group>
          <source>Global Status Report on Alcohol and Health 2018</source>
          <year>2018</year>
          <publisher-loc>Geneva, Switzerland</publisher-loc>
          <publisher-name>World Health Organization</publisher-name>
        </nlm-citation>
      </ref>
      <ref id="ref4">
        <label>4</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <collab>GBD 2017 Diet Collaborators</collab>
          </person-group>
          <article-title>Health effects of dietary risks in 195 countries, 1990-2017: a systematic analysis for the global burden of disease study 2017</article-title>
          <source>Lancet</source>
          <year>2019</year>
          <month>05</month>
          <day>11</day>
          <volume>393</volume>
          <issue>10184</issue>
          <fpage>1958</fpage>
          <lpage>72</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://linkinghub.elsevier.com/retrieve/pii/S0140-6736(19)30041-8"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/S0140-6736(19)30041-8</pub-id>
          <pub-id pub-id-type="medline">30954305</pub-id>
          <pub-id pub-id-type="pii">S0140-6736(19)30041-8</pub-id>
          <pub-id pub-id-type="pmcid">PMC6899507</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref5">
        <label>5</label>
        <nlm-citation citation-type="web">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Research</surname>
              <given-names>W</given-names>
            </name>
          </person-group>
          <article-title>Diet, Nutrition, Physical Activity and Cancer: a Global Perspective</article-title>
          <source>World Cancer Research Fund/American Institute for Cancer Research</source>
          <year>2018</year>
          <access-date>2020-03-26</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.wcrf.org/dietandcancer">https://www.wcrf.org/dietandcancer</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref6">
        <label>6</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Micha</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Shulkin</surname>
              <given-names>ML</given-names>
            </name>
            <name name-style="western">
              <surname>Peñalvo</surname>
              <given-names>JL</given-names>
            </name>
            <name name-style="western">
              <surname>Khatibzadeh</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Singh</surname>
              <given-names>GM</given-names>
            </name>
            <name name-style="western">
              <surname>Rao</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Fahimi</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Powles</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Mozaffarian</surname>
              <given-names>D</given-names>
            </name>
          </person-group>
          <article-title>Etiologic effects and optimal intakes of foods and nutrients for risk of cardiovascular diseases and diabetes: Systematic reviews and meta-analyses from the nutrition and chronic diseases expert group (NutriCoDE)</article-title>
          <source>PLoS One</source>
          <year>2017</year>
          <volume>12</volume>
          <issue>4</issue>
          <fpage>e0175149</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://dx.plos.org/10.1371/journal.pone.0175149"/>
          </comment>
          <pub-id pub-id-type="doi">10.1371/journal.pone.0175149</pub-id>
          <pub-id pub-id-type="medline">28448503</pub-id>
          <pub-id pub-id-type="pii">PONE-D-17-03607</pub-id>
          <pub-id pub-id-type="pmcid">PMC5407851</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref7">
        <label>7</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Lee</surname>
              <given-names>IM</given-names>
            </name>
            <name name-style="western">
              <surname>Shiroma</surname>
              <given-names>EJ</given-names>
            </name>
            <name name-style="western">
              <surname>Lobelo</surname>
              <given-names>F</given-names>
            </name>
            <name name-style="western">
              <surname>Puska</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Blair</surname>
              <given-names>SN</given-names>
            </name>
            <name name-style="western">
              <surname>Katzmarzyk</surname>
              <given-names>PT</given-names>
            </name>
            <collab>Lancet Physical Activity Series Working Group</collab>
          </person-group>
          <article-title>Effect of physical inactivity on major non-communicable diseases worldwide: an analysis of burden of disease and life expectancy</article-title>
          <source>Lancet</source>
          <year>2012</year>
          <month>07</month>
          <day>21</day>
          <volume>380</volume>
          <issue>9838</issue>
          <fpage>219</fpage>
          <lpage>29</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/22818936"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/S0140-6736(12)61031-9</pub-id>
          <pub-id pub-id-type="medline">22818936</pub-id>
          <pub-id pub-id-type="pii">S0140-6736(12)61031-9</pub-id>
          <pub-id pub-id-type="pmcid">PMC3645500</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref8">
        <label>8</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Roberts</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Spain</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Hicks</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>London</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Tay</surname>
              <given-names>S</given-names>
            </name>
          </person-group>
          <article-title>Telemedicine in the northern territory: an assessment of patient perceptions in the preoperative anaesthetic clinic</article-title>
          <source>Aust J Rural Health</source>
          <year>2015</year>
          <month>06</month>
          <volume>23</volume>
          <issue>3</issue>
          <fpage>136</fpage>
          <lpage>41</lpage>
          <pub-id pub-id-type="doi">10.1111/ajr.12140</pub-id>
          <pub-id pub-id-type="medline">25615954</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref9">
        <label>9</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Wootton</surname>
              <given-names>R</given-names>
            </name>
          </person-group>
          <article-title>Twenty years of telemedicine in chronic disease management--an evidence synthesis</article-title>
          <source>J Telemed Telecare</source>
          <year>2012</year>
          <month>06</month>
          <volume>18</volume>
          <issue>4</issue>
          <fpage>211</fpage>
          <lpage>20</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/22674020"/>
          </comment>
          <pub-id pub-id-type="doi">10.1258/jtt.2012.120219</pub-id>
          <pub-id pub-id-type="medline">22674020</pub-id>
          <pub-id pub-id-type="pii">18/4/211</pub-id>
          <pub-id pub-id-type="pmcid">PMC3366107</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref10">
        <label>10</label>
        <nlm-citation citation-type="web">
          <article-title>Number of Internet Users Worldwide From 2005 to 2019 (in Millions)</article-title>
          <source>Statistica</source>
          <year>2019</year>
          <access-date>2019-12-03</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.statista.com/statistics/273018/number-of-internet-users-worldwide/">https://www.statista.com/statistics/273018/number-of-internet-users-worldwide/</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref11">
        <label>11</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Ventola</surname>
              <given-names>CL</given-names>
            </name>
          </person-group>
          <article-title>Social media and health care professionals: benefits, risks, and best practices</article-title>
          <source>P T</source>
          <year>2014</year>
          <month>07</month>
          <volume>39</volume>
          <issue>7</issue>
          <fpage>491</fpage>
          <lpage>520</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/25083128"/>
          </comment>
          <pub-id pub-id-type="medline">25083128</pub-id>
          <pub-id pub-id-type="pmcid">PMC4103576</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref12">
        <label>12</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Wade</surname>
              <given-names>VA</given-names>
            </name>
            <name name-style="western">
              <surname>Karnon</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Elshaug</surname>
              <given-names>AG</given-names>
            </name>
            <name name-style="western">
              <surname>Hiller</surname>
              <given-names>JE</given-names>
            </name>
          </person-group>
          <article-title>A systematic review of economic analyses of telehealth services using real time video communication</article-title>
          <source>BMC Health Serv Res</source>
          <year>2010</year>
          <month>08</month>
          <day>10</day>
          <volume>10</volume>
          <fpage>233</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://bmchealthservres.biomedcentral.com/articles/10.1186/1472-6963-10-233"/>
          </comment>
          <pub-id pub-id-type="doi">10.1186/1472-6963-10-233</pub-id>
          <pub-id pub-id-type="medline">20696073</pub-id>
          <pub-id pub-id-type="pii">1472-6963-10-233</pub-id>
          <pub-id pub-id-type="pmcid">PMC2927589</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref13">
        <label>13</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Free</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Phillips</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Galli</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Watson</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Felix</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Edwards</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Patel</surname>
              <given-names>V</given-names>
            </name>
            <name name-style="western">
              <surname>Haines</surname>
              <given-names>A</given-names>
            </name>
          </person-group>
          <article-title>The effectiveness of mobile-health technology-based health behaviour change or disease management interventions for health care consumers: a systematic review</article-title>
          <source>PLoS Med</source>
          <year>2013</year>
          <volume>10</volume>
          <issue>1</issue>
          <fpage>e1001362</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://dx.plos.org/10.1371/journal.pmed.1001362"/>
          </comment>
          <pub-id pub-id-type="doi">10.1371/journal.pmed.1001362</pub-id>
          <pub-id pub-id-type="medline">23349621</pub-id>
          <pub-id pub-id-type="pii">PMEDICINE-D-12-00520</pub-id>
          <pub-id pub-id-type="pmcid">PMC3548655</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref14">
        <label>14</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Daft</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Lengel</surname>
              <given-names>R</given-names>
            </name>
          </person-group>
          <article-title>Information richness: a new approach to managerial behavior and organization design Research in organizational behavior</article-title>
          <source>J Mark Res</source>
          <year>1984</year>
          <volume>6</volume>
          <fpage>-</fpage>
          <pub-id pub-id-type="doi">10.21236/ada128980</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref15">
        <label>15</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Copeland</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Martin</surname>
              <given-names>G</given-names>
            </name>
          </person-group>
          <article-title>Web-based interventions for substance use disorders: a qualitative review</article-title>
          <source>J Subst Abuse Treat</source>
          <year>2004</year>
          <month>03</month>
          <volume>26</volume>
          <issue>2</issue>
          <fpage>109</fpage>
          <lpage>16</lpage>
          <pub-id pub-id-type="doi">10.1016/S0740-5472(03)00165-X</pub-id>
          <pub-id pub-id-type="medline">15050088</pub-id>
          <pub-id pub-id-type="pii">S074054720300165X</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref16">
        <label>16</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Rochlen</surname>
              <given-names>AB</given-names>
            </name>
            <name name-style="western">
              <surname>Zack</surname>
              <given-names>JS</given-names>
            </name>
            <name name-style="western">
              <surname>Speyer</surname>
              <given-names>C</given-names>
            </name>
          </person-group>
          <article-title>Online therapy: review of relevant definitions, debates, and current empirical support</article-title>
          <source>J Clin Psychol</source>
          <year>2004</year>
          <month>03</month>
          <volume>60</volume>
          <issue>3</issue>
          <fpage>269</fpage>
          <lpage>83</lpage>
          <pub-id pub-id-type="doi">10.1002/jclp.10263</pub-id>
          <pub-id pub-id-type="medline">14981791</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref17">
        <label>17</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Lancaster</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Stead</surname>
              <given-names>L</given-names>
            </name>
          </person-group>
          <article-title>Individual behavioural counselling for smoking cessation</article-title>
          <source>Cochrane Database Syst Rev</source>
          <year>2017</year>
          <month>03</month>
          <day>31</day>
          <volume>3</volume>
          <fpage>CD001292</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/28361496"/>
          </comment>
          <pub-id pub-id-type="doi">10.1002/14651858.CD001292.pub3</pub-id>
          <pub-id pub-id-type="medline">28361496</pub-id>
          <pub-id pub-id-type="pmcid">PMC6464359</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref18">
        <label>18</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Au</surname>
              <given-names>LE</given-names>
            </name>
            <name name-style="western">
              <surname>Whaley</surname>
              <given-names>SE</given-names>
            </name>
            <name name-style="western">
              <surname>Gurzo</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Meza</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Rosen</surname>
              <given-names>NJ</given-names>
            </name>
            <name name-style="western">
              <surname>Ritchie</surname>
              <given-names>LD</given-names>
            </name>
          </person-group>
          <article-title>Evaluation of online and in-person nutrition education related to salt knowledge and behaviors among special supplemental nutrition program for women, infants, and children participants</article-title>
          <source>J Acad Nutr Diet</source>
          <year>2017</year>
          <month>09</month>
          <volume>117</volume>
          <issue>9</issue>
          <fpage>1384</fpage>
          <lpage>95</lpage>
          <pub-id pub-id-type="doi">10.1016/j.jand.2016.12.013</pub-id>
          <pub-id pub-id-type="medline">28196620</pub-id>
          <pub-id pub-id-type="pii">S2212-2672(16)31548-9</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref19">
        <label>19</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>O'Hara</surname>
              <given-names>BJ</given-names>
            </name>
            <name name-style="western">
              <surname>Phongsavan</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Venugopal</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Eakin</surname>
              <given-names>EG</given-names>
            </name>
            <name name-style="western">
              <surname>Eggins</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Caterson</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>King</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Allman-Farinelli</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Haas</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Bauman</surname>
              <given-names>AE</given-names>
            </name>
          </person-group>
          <article-title>Effectiveness of australia's get healthy information and coaching service: translational research with population wide impact</article-title>
          <source>Prev Med</source>
          <year>2012</year>
          <month>10</month>
          <volume>55</volume>
          <issue>4</issue>
          <fpage>292</fpage>
          <lpage>8</lpage>
          <pub-id pub-id-type="doi">10.1016/j.ypmed.2012.07.022</pub-id>
          <pub-id pub-id-type="medline">22885323</pub-id>
          <pub-id pub-id-type="pii">S0091-7435(12)00332-5</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref20">
        <label>20</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Freyer-Adam</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Baumann</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Haberecht</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Tobschall</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Bischof</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>John</surname>
              <given-names>U</given-names>
            </name>
            <name name-style="western">
              <surname>Gaertner</surname>
              <given-names>B</given-names>
            </name>
          </person-group>
          <article-title>In-person alcohol counseling versus computer-generated feedback: results from a randomized controlled trial</article-title>
          <source>Health Psychol</source>
          <year>2018</year>
          <month>01</month>
          <volume>37</volume>
          <issue>1</issue>
          <fpage>70</fpage>
          <lpage>80</lpage>
          <pub-id pub-id-type="doi">10.1037/hea0000556</pub-id>
          <pub-id pub-id-type="medline">28967769</pub-id>
          <pub-id pub-id-type="pii">2017-44269-001</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref21">
        <label>21</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Borland</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Segan</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Livingston</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Owen</surname>
              <given-names>N</given-names>
            </name>
          </person-group>
          <article-title>The effectiveness of callback counselling for smoking cessation: a randomized trial</article-title>
          <source>Addiction</source>
          <year>2001</year>
          <month>06</month>
          <volume>96</volume>
          <issue>6</issue>
          <fpage>881</fpage>
          <lpage>9</lpage>
          <pub-id pub-id-type="doi">10.1046/j.1360-0443.2001.9668819.x</pub-id>
          <pub-id pub-id-type="medline">11399219</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref22">
        <label>22</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Owen</surname>
              <given-names>L</given-names>
            </name>
          </person-group>
          <article-title>Impact of a telephone helpline for smokers who called during a mass media campaign</article-title>
          <source>Tob Control</source>
          <year>2000</year>
          <month>06</month>
          <volume>9</volume>
          <issue>2</issue>
          <fpage>148</fpage>
          <lpage>54</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="http://tobaccocontrol.bmj.com/cgi/pmidlookup?view=long&#38;pmid=10841850"/>
          </comment>
          <pub-id pub-id-type="doi">10.1136/tc.9.2.148</pub-id>
          <pub-id pub-id-type="medline">10841850</pub-id>
          <pub-id pub-id-type="pmcid">PMC1748342</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref23">
        <label>23</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Lindqvist</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Forsberg</surname>
              <given-names>LG</given-names>
            </name>
            <name name-style="western">
              <surname>Forsberg</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Rosendahl</surname>
              <given-names>I</given-names>
            </name>
            <name name-style="western">
              <surname>Enebrink</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Helgason</surname>
              <given-names>AR</given-names>
            </name>
          </person-group>
          <article-title>Motivational interviewing in an ordinary clinical setting: a controlled clinical trial at the Swedish national tobacco quitline</article-title>
          <source>Addict Behav</source>
          <year>2013</year>
          <month>07</month>
          <volume>38</volume>
          <issue>7</issue>
          <fpage>2321</fpage>
          <lpage>4</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://linkinghub.elsevier.com/retrieve/pii/S0306-4603(13)00074-9"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/j.addbeh.2013.03.002</pub-id>
          <pub-id pub-id-type="medline">23584193</pub-id>
          <pub-id pub-id-type="pii">S0306-4603(13)00074-9</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref24">
        <label>24</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Skov-Ettrup</surname>
              <given-names>LS</given-names>
            </name>
            <name name-style="western">
              <surname>Dalum</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Bech</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Tolstrup</surname>
              <given-names>JS</given-names>
            </name>
          </person-group>
          <article-title>The effectiveness of telephone counselling and internet- and text-message-based support for smoking cessation: results from a randomized controlled trial</article-title>
          <source>Addiction</source>
          <year>2016</year>
          <month>07</month>
          <volume>111</volume>
          <issue>7</issue>
          <fpage>1257</fpage>
          <lpage>66</lpage>
          <pub-id pub-id-type="doi">10.1111/add.13302</pub-id>
          <pub-id pub-id-type="medline">26748541</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref25">
        <label>25</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Goode</surname>
              <given-names>AD</given-names>
            </name>
            <name name-style="western">
              <surname>Lawler</surname>
              <given-names>SP</given-names>
            </name>
            <name name-style="western">
              <surname>Brakenridge</surname>
              <given-names>CL</given-names>
            </name>
            <name name-style="western">
              <surname>Reeves</surname>
              <given-names>MM</given-names>
            </name>
            <name name-style="western">
              <surname>Eakin</surname>
              <given-names>EG</given-names>
            </name>
          </person-group>
          <article-title>Telephone, print, and Web-based interventions for physical activity, diet, and weight control among cancer survivors: a systematic review</article-title>
          <source>J Cancer Surviv</source>
          <year>2015</year>
          <month>12</month>
          <volume>9</volume>
          <issue>4</issue>
          <fpage>660</fpage>
          <lpage>82</lpage>
          <pub-id pub-id-type="doi">10.1007/s11764-015-0442-2</pub-id>
          <pub-id pub-id-type="medline">25757733</pub-id>
          <pub-id pub-id-type="pii">10.1007/s11764-015-0442-2</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref26">
        <label>26</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Desroches</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Lapointe</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Ratté</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Gravel</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Légaré</surname>
              <given-names>F</given-names>
            </name>
            <name name-style="western">
              <surname>Turcotte</surname>
              <given-names>S</given-names>
            </name>
          </person-group>
          <article-title>Interventions to enhance adherence to dietary advice for preventing and managing chronic diseases in adults</article-title>
          <source>Cochrane Database Syst Rev</source>
          <year>2013</year>
          <month>02</month>
          <day>28</day>
          <issue>2</issue>
          <fpage>CD008722</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/23450587"/>
          </comment>
          <pub-id pub-id-type="doi">10.1002/14651858.CD008722.pub2</pub-id>
          <pub-id pub-id-type="medline">23450587</pub-id>
          <pub-id pub-id-type="pmcid">PMC4900876</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref27">
        <label>27</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Stead</surname>
              <given-names>LF</given-names>
            </name>
            <name name-style="western">
              <surname>Hartmann-Boyce</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Perera</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Lancaster</surname>
              <given-names>T</given-names>
            </name>
          </person-group>
          <article-title>Telephone counselling for smoking cessation</article-title>
          <source>Cochrane Database Syst Rev</source>
          <year>2013</year>
          <month>08</month>
          <day>12</day>
          <issue>8</issue>
          <fpage>CD002850</fpage>
          <pub-id pub-id-type="doi">10.1002/14651858.CD002850.pub3</pub-id>
          <pub-id pub-id-type="medline">23934971</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref28">
        <label>28</label>
        <nlm-citation citation-type="book">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>McMahon</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Palmer</surname>
              <given-names>S</given-names>
            </name>
          </person-group>
          <source>Handbook of Counselling Psychology</source>
          <year>2014</year>
          <publisher-loc>New York, USA</publisher-loc>
          <publisher-name>Routledge</publisher-name>
        </nlm-citation>
      </ref>
      <ref id="ref29">
        <label>29</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Michie</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>van Stralen</surname>
              <given-names>MM</given-names>
            </name>
            <name name-style="western">
              <surname>West</surname>
              <given-names>R</given-names>
            </name>
          </person-group>
          <article-title>The behaviour change wheel: a new method for characterising and designing behaviour change interventions</article-title>
          <source>Implement Sci</source>
          <year>2011</year>
          <month>04</month>
          <day>23</day>
          <volume>6</volume>
          <fpage>42</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://implementationscience.biomedcentral.com/articles/10.1186/1748-5908-6-42"/>
          </comment>
          <pub-id pub-id-type="doi">10.1186/1748-5908-6-42</pub-id>
          <pub-id pub-id-type="medline">21513547</pub-id>
          <pub-id pub-id-type="pii">1748-5908-6-42</pub-id>
          <pub-id pub-id-type="pmcid">PMC3096582</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref30">
        <label>30</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Boland</surname>
              <given-names>V</given-names>
            </name>
            <name name-style="western">
              <surname>Stockings</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Mattick</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>McRobbie</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Brown</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Courtney</surname>
              <given-names>R</given-names>
            </name>
          </person-group>
          <article-title>The methodological quality and effectiveness of technology-based smoking cessation interventions for disadvantaged groups: a systematic review and meta-analysis</article-title>
          <source>Nicotine Tob Res</source>
          <year>2018</year>
          <month>02</month>
          <day>7</day>
          <volume>20</volume>
          <issue>3</issue>
          <fpage>276</fpage>
          <lpage>85</lpage>
          <pub-id pub-id-type="doi">10.1093/ntr/ntw391</pub-id>
          <pub-id pub-id-type="medline">28034998</pub-id>
          <pub-id pub-id-type="pii">ntw391</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref31">
        <label>31</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Richter</surname>
              <given-names>KP</given-names>
            </name>
            <name name-style="western">
              <surname>Shireman</surname>
              <given-names>TI</given-names>
            </name>
            <name name-style="western">
              <surname>Ellerbeck</surname>
              <given-names>EF</given-names>
            </name>
            <name name-style="western">
              <surname>Cupertino</surname>
              <given-names>AP</given-names>
            </name>
            <name name-style="western">
              <surname>Catley</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Cox</surname>
              <given-names>LS</given-names>
            </name>
            <name name-style="western">
              <surname>Preacher</surname>
              <given-names>KJ</given-names>
            </name>
            <name name-style="western">
              <surname>Spaulding</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Mussulman</surname>
              <given-names>LM</given-names>
            </name>
            <name name-style="western">
              <surname>Nazir</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Hunt</surname>
              <given-names>JJ</given-names>
            </name>
            <name name-style="western">
              <surname>Lambart</surname>
              <given-names>L</given-names>
            </name>
          </person-group>
          <article-title>Comparative and cost effectiveness of telemedicine versus telephone counseling for smoking cessation</article-title>
          <source>J Med Internet Res</source>
          <year>2015</year>
          <month>05</month>
          <day>8</day>
          <volume>17</volume>
          <issue>5</issue>
          <fpage>e113</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.jmir.org/2015/5/e113/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/jmir.3975</pub-id>
          <pub-id pub-id-type="medline">25956257</pub-id>
          <pub-id pub-id-type="pii">v17i5e113</pub-id>
          <pub-id pub-id-type="pmcid">PMC4468596</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref32">
        <label>32</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Tzelepis</surname>
              <given-names>F</given-names>
            </name>
            <name name-style="western">
              <surname>Paul</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Williams</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Gilligan</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Regan</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Daly</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Hodder</surname>
              <given-names>RK</given-names>
            </name>
            <name name-style="western">
              <surname>Byrnes</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Byaruhanga</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>McFadyen</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Wiggers</surname>
              <given-names>J</given-names>
            </name>
          </person-group>
          <article-title>Real-time video counselling for smoking cessation</article-title>
          <source>Cochrane Database Syst Rev</source>
          <year>2019</year>
          <month>10</month>
          <day>29</day>
          <volume>2019</volume>
          <issue>10</issue>
          <fpage>1</fpage>
          <lpage>13</lpage>
          <pub-id pub-id-type="doi">10.1002/14651858.CD012659.pub2</pub-id>
          <pub-id pub-id-type="medline">31684699</pub-id>
          <pub-id pub-id-type="pmcid">PMC6818086</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref33">
        <label>33</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Moher</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Liberati</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Tetzlaff</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Altman</surname>
              <given-names>DG</given-names>
            </name>
            <collab>PRISMA Group</collab>
          </person-group>
          <article-title>Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement</article-title>
          <source>Br Med J</source>
          <year>2009</year>
          <month>07</month>
          <day>21</day>
          <volume>339</volume>
          <fpage>b2535</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="http://www.bmj.com/cgi/pmidlookup?view=long&#38;pmid=19622551"/>
          </comment>
          <pub-id pub-id-type="doi">10.1136/bmj.b2535</pub-id>
          <pub-id pub-id-type="medline">19622551</pub-id>
          <pub-id pub-id-type="pmcid">PMC2714657</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref34">
        <label>34</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Hariton</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Locascio</surname>
              <given-names>JJ</given-names>
            </name>
          </person-group>
          <article-title>Randomised controlled trials - the gold standard for effectiveness research: study design: randomised controlled trials</article-title>
          <source>BJOG</source>
          <year>2018</year>
          <month>12</month>
          <volume>125</volume>
          <issue>13</issue>
          <fpage>1716</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://doi.org/10.1111/1471-0528.15199"/>
          </comment>
          <pub-id pub-id-type="doi">10.1111/1471-0528.15199</pub-id>
          <pub-id pub-id-type="medline">29916205</pub-id>
          <pub-id pub-id-type="pmcid">PMC6235704</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref35">
        <label>35</label>
        <nlm-citation citation-type="web">
          <article-title>Quality Assessment Tool for Quantitative Studies Dictionary</article-title>
          <source>EPHPP – McMaster Evidence Review &#38; Synthesis Centre</source>
          <year>2010</year>
          <access-date>2019-01-16</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://merst.ca/wp-content/uploads/2018/02/qualilty-assessment-dictionary_2017.pdf">https://merst.ca/wp-content/uploads/2018/02/qualilty-assessment-dictionary_2017.pdf</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref36">
        <label>36</label>
        <nlm-citation citation-type="web">
          <article-title>Quality Assessment Tool for Quantitative Studies</article-title>
          <source>National Collaborating Centre for Methods and Tools</source>
          <year>2017</year>
          <access-date>2019-01-16</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.nccmt.ca/knowledge-repositories/search/14">https://www.nccmt.ca/knowledge-repositories/search/14</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref37">
        <label>37</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Azar</surname>
              <given-names>KM</given-names>
            </name>
            <name name-style="western">
              <surname>Aurora</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Wang</surname>
              <given-names>EJ</given-names>
            </name>
            <name name-style="western">
              <surname>Muzaffar</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Pressman</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Palaniappan</surname>
              <given-names>LP</given-names>
            </name>
          </person-group>
          <article-title>Virtual small groups for weight management: an innovative delivery mechanism for evidence-based lifestyle interventions among obese men</article-title>
          <source>Transl Behav Med</source>
          <year>2015</year>
          <month>03</month>
          <volume>5</volume>
          <issue>1</issue>
          <fpage>37</fpage>
          <lpage>44</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/25729451"/>
          </comment>
          <pub-id pub-id-type="doi">10.1007/s13142-014-0296-6</pub-id>
          <pub-id pub-id-type="medline">25729451</pub-id>
          <pub-id pub-id-type="pii">296</pub-id>
          <pub-id pub-id-type="pmcid">PMC4332901</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref38">
        <label>38</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Davis</surname>
              <given-names>AM</given-names>
            </name>
            <name name-style="western">
              <surname>Sampilo</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Gallagher</surname>
              <given-names>KS</given-names>
            </name>
            <name name-style="western">
              <surname>Dean</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Saroja</surname>
              <given-names>MB</given-names>
            </name>
            <name name-style="western">
              <surname>Yu</surname>
              <given-names>Q</given-names>
            </name>
            <name name-style="western">
              <surname>He</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Sporn</surname>
              <given-names>N</given-names>
            </name>
          </person-group>
          <article-title>Treating rural paediatric obesity through telemedicine vs telephone: outcomes from a cluster randomized controlled trial</article-title>
          <source>J Telemed Telecare</source>
          <year>2016</year>
          <month>03</month>
          <volume>22</volume>
          <issue>2</issue>
          <fpage>86</fpage>
          <lpage>95</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/26026186"/>
          </comment>
          <pub-id pub-id-type="doi">10.1177/1357633X15586642</pub-id>
          <pub-id pub-id-type="medline">26026186</pub-id>
          <pub-id pub-id-type="pii">1357633X15586642</pub-id>
          <pub-id pub-id-type="pmcid">PMC4830380</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref39">
        <label>39</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Davis</surname>
              <given-names>AM</given-names>
            </name>
            <name name-style="western">
              <surname>Sampilo</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Gallagher</surname>
              <given-names>KS</given-names>
            </name>
            <name name-style="western">
              <surname>Landrum</surname>
              <given-names>Y</given-names>
            </name>
            <name name-style="western">
              <surname>Malone</surname>
              <given-names>B</given-names>
            </name>
          </person-group>
          <article-title>Treating rural pediatric obesity through telemedicine: outcomes from a small randomized controlled trial</article-title>
          <source>J Pediatr Psychol</source>
          <year>2013</year>
          <month>10</month>
          <volume>38</volume>
          <issue>9</issue>
          <fpage>932</fpage>
          <lpage>43</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/23428652"/>
          </comment>
          <pub-id pub-id-type="doi">10.1093/jpepsy/jst005</pub-id>
          <pub-id pub-id-type="medline">23428652</pub-id>
          <pub-id pub-id-type="pii">jst005</pub-id>
          <pub-id pub-id-type="pmcid">PMC3785218</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref40">
        <label>40</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Ehlers</surname>
              <given-names>DK</given-names>
            </name>
            <name name-style="western">
              <surname>Huberty</surname>
              <given-names>JL</given-names>
            </name>
            <name name-style="western">
              <surname>de Vreede</surname>
              <given-names>G</given-names>
            </name>
          </person-group>
          <article-title>Can an evidence-based book club intervention delivered via a tablet computer improve physical activity in middle-aged women?</article-title>
          <source>Telemed J E Health</source>
          <year>2015</year>
          <month>02</month>
          <volume>21</volume>
          <issue>2</issue>
          <fpage>125</fpage>
          <lpage>31</lpage>
          <pub-id pub-id-type="doi">10.1089/tmj.2013.0360</pub-id>
          <pub-id pub-id-type="medline">25526014</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref41">
        <label>41</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Wild</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Hünnemeyer</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Sauer</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Hain</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Mack</surname>
              <given-names>I</given-names>
            </name>
            <name name-style="western">
              <surname>Schellberg</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Müller-Stich</surname>
              <given-names>BP</given-names>
            </name>
            <name name-style="western">
              <surname>Weiner</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Meile</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Rudofsky</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Königsrainer</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Zipfel</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Herzog</surname>
              <given-names>W</given-names>
            </name>
            <name name-style="western">
              <surname>Teufel</surname>
              <given-names>M</given-names>
            </name>
          </person-group>
          <article-title>A 1-year videoconferencing-based psychoeducational group intervention following bariatric surgery: results of a randomized controlled study</article-title>
          <source>Surg Obes Relat Dis</source>
          <year>2015</year>
          <volume>11</volume>
          <issue>6</issue>
          <fpage>1349</fpage>
          <lpage>60</lpage>
          <pub-id pub-id-type="doi">10.1016/j.soard.2015.05.018</pub-id>
          <pub-id pub-id-type="medline">26421929</pub-id>
          <pub-id pub-id-type="pii">S1550-7289(15)00162-8</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref42">
        <label>42</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Nelson</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Yadrich</surname>
              <given-names>DM</given-names>
            </name>
            <name name-style="western">
              <surname>Thompson</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Wright</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Stone</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Adams</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Werkowitch</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Smith</surname>
              <given-names>CE</given-names>
            </name>
          </person-group>
          <article-title>Telemedicine support groups for home parenteral nutrition users</article-title>
          <source>Nutr Clin Pract</source>
          <year>2017</year>
          <month>12</month>
          <volume>32</volume>
          <issue>6</issue>
          <fpage>789</fpage>
          <lpage>98</lpage>
          <pub-id pub-id-type="doi">10.1177/0884533617735527</pub-id>
          <pub-id pub-id-type="medline">29016235</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref43">
        <label>43</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Nolan</surname>
              <given-names>RP</given-names>
            </name>
            <name name-style="western">
              <surname>Upshur</surname>
              <given-names>RE</given-names>
            </name>
            <name name-style="western">
              <surname>Lynn</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Crichton</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Rukholm</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Stewart</surname>
              <given-names>DE</given-names>
            </name>
            <name name-style="western">
              <surname>Alter</surname>
              <given-names>DA</given-names>
            </name>
            <name name-style="western">
              <surname>Chessex</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Harvey</surname>
              <given-names>PJ</given-names>
            </name>
            <name name-style="western">
              <surname>Grace</surname>
              <given-names>SL</given-names>
            </name>
            <name name-style="western">
              <surname>Picard</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Michel</surname>
              <given-names>I</given-names>
            </name>
            <name name-style="western">
              <surname>Angus</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Corace</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Barry-Bianchi</surname>
              <given-names>SM</given-names>
            </name>
            <name name-style="western">
              <surname>Chen</surname>
              <given-names>MH</given-names>
            </name>
          </person-group>
          <article-title>Therapeutic benefit of preventive telehealth counseling in the community outreach heart health and risk reduction trial</article-title>
          <source>Am J Cardiol</source>
          <year>2011</year>
          <month>03</month>
          <day>1</day>
          <volume>107</volume>
          <issue>5</issue>
          <fpage>690</fpage>
          <lpage>6</lpage>
          <pub-id pub-id-type="doi">10.1016/j.amjcard.2010.10.050</pub-id>
          <pub-id pub-id-type="medline">21215382</pub-id>
          <pub-id pub-id-type="pii">S0002-9149(10)02245-9</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref44">
        <label>44</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Tsai</surname>
              <given-names>LL</given-names>
            </name>
            <name name-style="western">
              <surname>McNamara</surname>
              <given-names>RJ</given-names>
            </name>
            <name name-style="western">
              <surname>Moddel</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Alison</surname>
              <given-names>JA</given-names>
            </name>
            <name name-style="western">
              <surname>McKenzie</surname>
              <given-names>DK</given-names>
            </name>
            <name name-style="western">
              <surname>McKeough</surname>
              <given-names>ZJ</given-names>
            </name>
          </person-group>
          <article-title>Home-based telerehabilitation via real-time videoconferencing improves endurance exercise capacity in patients with COPD: the randomized controlled TeleR study</article-title>
          <source>Respirology</source>
          <year>2017</year>
          <month>05</month>
          <volume>22</volume>
          <issue>4</issue>
          <fpage>699</fpage>
          <lpage>707</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://doi.org/10.1111/resp.12966"/>
          </comment>
          <pub-id pub-id-type="doi">10.1111/resp.12966</pub-id>
          <pub-id pub-id-type="medline">27992099</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref45">
        <label>45</label>
        <nlm-citation citation-type="confproc">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Huennemeyer</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Teufel</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Hain</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Rieber</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Sauer</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Rudofsky</surname>
              <given-names>G</given-names>
            </name>
          </person-group>
          <article-title>The Base for a Balanced Life - The Randomized Controlled Base (Bariatric Surgery and Education) Study</article-title>
          <source>16th Congress of the International Federation for the Surgery</source>
          <year>2011</year>
          <conf-name>IFS'11</conf-name>
          <conf-date>August 31-September 3, 2011</conf-date>
          <conf-loc>Hamburg, Germany</conf-loc>
        </nlm-citation>
      </ref>
      <ref id="ref46">
        <label>46</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Wu</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Keyes</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Callas</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Ren</surname>
              <given-names>X</given-names>
            </name>
            <name name-style="western">
              <surname>Bookchin</surname>
              <given-names>B</given-names>
            </name>
          </person-group>
          <article-title>Comparison of telecommunication, community, and home-based Tai Chi exercise programs on compliance and effectiveness in elders at risk for falls</article-title>
          <source>Arch Phys Med Rehabil</source>
          <year>2010</year>
          <month>06</month>
          <volume>91</volume>
          <issue>6</issue>
          <fpage>849</fpage>
          <lpage>56</lpage>
          <pub-id pub-id-type="doi">10.1016/j.apmr.2010.01.024</pub-id>
          <pub-id pub-id-type="medline">20510973</pub-id>
          <pub-id pub-id-type="pii">S0003-9993(10)00124-3</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref47">
        <label>47</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Hwang</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Morris</surname>
              <given-names>NR</given-names>
            </name>
            <name name-style="western">
              <surname>Mandrusiak</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Bruning</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Peters</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Korczyk</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Russell</surname>
              <given-names>T</given-names>
            </name>
          </person-group>
          <article-title>Cost-utility analysis of home-based telerehabilitation compared with centre-based rehabilitation in patients with heart failure</article-title>
          <source>Heart Lung Circ</source>
          <year>2019</year>
          <month>12</month>
          <volume>28</volume>
          <issue>12</issue>
          <fpage>1795</fpage>
          <lpage>803</lpage>
          <pub-id pub-id-type="doi">10.1016/j.hlc.2018.11.010</pub-id>
          <pub-id pub-id-type="medline">30528811</pub-id>
          <pub-id pub-id-type="pii">S1443-9506(18)31995-4</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref48">
        <label>48</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Hwang</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Bruning</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Morris</surname>
              <given-names>NR</given-names>
            </name>
            <name name-style="western">
              <surname>Mandrusiak</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Russell</surname>
              <given-names>T</given-names>
            </name>
          </person-group>
          <article-title>Home-based telerehabilitation is not inferior to a centre-based program in patients with chronic heart failure: a randomised trial</article-title>
          <source>J Physiother</source>
          <year>2017</year>
          <month>04</month>
          <volume>63</volume>
          <issue>2</issue>
          <fpage>101</fpage>
          <lpage>7</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://linkinghub.elsevier.com/retrieve/pii/S1836-9553(17)30031-0"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/j.jphys.2017.02.017</pub-id>
          <pub-id pub-id-type="medline">28336297</pub-id>
          <pub-id pub-id-type="pii">S1836-9553(17)30031-0</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref49">
        <label>49</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Porter</surname>
              <given-names>LS</given-names>
            </name>
            <name name-style="western">
              <surname>Gao</surname>
              <given-names>X</given-names>
            </name>
            <name name-style="western">
              <surname>Lyna</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Kraus</surname>
              <given-names>W</given-names>
            </name>
            <name name-style="western">
              <surname>Olsen</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Patterson</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Puleo</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Pollak</surname>
              <given-names>KI</given-names>
            </name>
          </person-group>
          <article-title>Pilot randomized trial of a couple-based physical activity videoconference intervention for sedentary cancer survivors</article-title>
          <source>Health Psychol</source>
          <year>2018</year>
          <month>09</month>
          <volume>37</volume>
          <issue>9</issue>
          <fpage>861</fpage>
          <lpage>5</lpage>
          <pub-id pub-id-type="doi">10.1037/hea0000608</pub-id>
          <pub-id pub-id-type="medline">30138021</pub-id>
          <pub-id pub-id-type="pii">2018-41555-004</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref50">
        <label>50</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Clark</surname>
              <given-names>DO</given-names>
            </name>
            <name name-style="western">
              <surname>Keith</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Weiner</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Xu</surname>
              <given-names>H</given-names>
            </name>
          </person-group>
          <article-title>Outcomes of an RCT of videoconference vs in-person or in-clinic nutrition and exercise in midlife adults with obesity</article-title>
          <source>Obes Sci Pract</source>
          <year>2019</year>
          <month>04</month>
          <volume>5</volume>
          <issue>2</issue>
          <fpage>111</fpage>
          <lpage>9</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/31019728"/>
          </comment>
          <pub-id pub-id-type="doi">10.1002/osp4.318</pub-id>
          <pub-id pub-id-type="medline">31019728</pub-id>
          <pub-id pub-id-type="pii">OSP4318</pub-id>
          <pub-id pub-id-type="pmcid">PMC6469332</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref51">
        <label>51</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>West</surname>
              <given-names>DS</given-names>
            </name>
            <name name-style="western">
              <surname>Stansbury</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Krukowski</surname>
              <given-names>RA</given-names>
            </name>
            <name name-style="western">
              <surname>Harvey</surname>
              <given-names>J</given-names>
            </name>
          </person-group>
          <article-title>Enhancing group-based internet obesity treatment: a pilot RCT comparing video and text-based chat</article-title>
          <source>Obes Sci Pract</source>
          <year>2019</year>
          <month>12</month>
          <volume>5</volume>
          <issue>6</issue>
          <fpage>513</fpage>
          <lpage>20</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/31890241"/>
          </comment>
          <pub-id pub-id-type="doi">10.1002/osp4.371</pub-id>
          <pub-id pub-id-type="medline">31890241</pub-id>
          <pub-id pub-id-type="pii">OSP4371</pub-id>
          <pub-id pub-id-type="pmcid">PMC6934426</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref52">
        <label>52</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Rosas</surname>
              <given-names>LG</given-names>
            </name>
            <name name-style="western">
              <surname>Lv</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Azar</surname>
              <given-names>KM</given-names>
            </name>
            <name name-style="western">
              <surname>Xiao</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Hooker</surname>
              <given-names>SP</given-names>
            </name>
            <name name-style="western">
              <surname>Lewis</surname>
              <given-names>MA</given-names>
            </name>
            <name name-style="western">
              <surname>Zavella</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Venditti</surname>
              <given-names>EM</given-names>
            </name>
            <name name-style="western">
              <surname>Ma</surname>
              <given-names>J</given-names>
            </name>
          </person-group>
          <article-title>Hombre: a randomized controlled trial to compare two approaches to weight loss for overweight and obese latino men (hombres con opciones para mejorar el bienestar y bajar el riesgo de enfermedades crónicas; men with choices to improve well-being and decrease chronic disease risk)</article-title>
          <source>Contemp Clin Trials</source>
          <year>2018</year>
          <month>05</month>
          <volume>68</volume>
          <fpage>23</fpage>
          <lpage>34</lpage>
          <pub-id pub-id-type="doi">10.1016/j.cct.2018.02.019</pub-id>
          <pub-id pub-id-type="medline">29505867</pub-id>
          <pub-id pub-id-type="pii">S1551-7144(17)30629-8</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref53">
        <label>53</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Mascarenhas</surname>
              <given-names>MN</given-names>
            </name>
            <name name-style="western">
              <surname>Chan</surname>
              <given-names>JM</given-names>
            </name>
            <name name-style="western">
              <surname>Vittinghoff</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>van Blarigan</surname>
              <given-names>EL</given-names>
            </name>
            <name name-style="western">
              <surname>Hecht</surname>
              <given-names>F</given-names>
            </name>
          </person-group>
          <article-title>Increasing physical activity in mothers using video exercise groups and exercise mobile apps: randomized controlled trial</article-title>
          <source>J Med Internet Res</source>
          <year>2018</year>
          <month>05</month>
          <day>18</day>
          <volume>20</volume>
          <issue>5</issue>
          <fpage>e179</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.jmir.org/2018/5/e179/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/jmir.9310</pub-id>
          <pub-id pub-id-type="medline">29776899</pub-id>
          <pub-id pub-id-type="pii">v20i5e179</pub-id>
          <pub-id pub-id-type="pmcid">PMC5984277</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref54">
        <label>54</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Chai</surname>
              <given-names>LK</given-names>
            </name>
            <name name-style="western">
              <surname>Collins</surname>
              <given-names>CE</given-names>
            </name>
            <name name-style="western">
              <surname>May</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Ashman</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Holder</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Brown</surname>
              <given-names>LJ</given-names>
            </name>
            <name name-style="western">
              <surname>Burrows</surname>
              <given-names>TL</given-names>
            </name>
          </person-group>
          <article-title>Feasibility and efficacy of a web-based family telehealth nutrition intervention to improve child weight status and dietary intake: a pilot randomised controlled trial</article-title>
          <source>J Telemed Telecare</source>
          <year>2019</year>
          <month>07</month>
          <day>31</day>
          <fpage>-</fpage>
          <comment>epub ahead of print</comment>
          <pub-id pub-id-type="doi">10.1177/1357633X19865855</pub-id>
          <pub-id pub-id-type="medline">31364474</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref55">
        <label>55</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Lynch</surname>
              <given-names>CP</given-names>
            </name>
            <name name-style="western">
              <surname>Williams</surname>
              <given-names>JS</given-names>
            </name>
            <name name-style="western">
              <surname>Ruggiero</surname>
              <given-names>KJ</given-names>
            </name>
            <name name-style="western">
              <surname>Knapp</surname>
              <given-names>RG</given-names>
            </name>
            <name name-style="western">
              <surname>Egede</surname>
              <given-names>LE</given-names>
            </name>
          </person-group>
          <article-title>Tablet-aided behavioral intervention effect on self-management skills (TABLETS) for diabetes</article-title>
          <source>Trials</source>
          <year>2016</year>
          <month>03</month>
          <day>22</day>
          <volume>17</volume>
          <fpage>157</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-016-1243-2"/>
          </comment>
          <pub-id pub-id-type="doi">10.1186/s13063-016-1243-2</pub-id>
          <pub-id pub-id-type="medline">27005766</pub-id>
          <pub-id pub-id-type="pii">10.1186/s13063-016-1243-2</pub-id>
          <pub-id pub-id-type="pmcid">PMC4804482</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref56">
        <label>56</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Zanaboni</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Dinesen</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Hjalmarsen</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Hoaas</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Holland</surname>
              <given-names>AE</given-names>
            </name>
            <name name-style="western">
              <surname>Oliveira</surname>
              <given-names>CC</given-names>
            </name>
            <name name-style="western">
              <surname>Wootton</surname>
              <given-names>R</given-names>
            </name>
          </person-group>
          <article-title>Long-term integrated telerehabilitation of COPD patients: a multicentre randomised controlled trial (iTrain)</article-title>
          <source>BMC Pulm Med</source>
          <year>2016</year>
          <month>08</month>
          <day>22</day>
          <volume>16</volume>
          <issue>1</issue>
          <fpage>126</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://bmcpulmmed.biomedcentral.com/articles/10.1186/s12890-016-0288-z"/>
          </comment>
          <pub-id pub-id-type="doi">10.1186/s12890-016-0288-z</pub-id>
          <pub-id pub-id-type="medline">27549782</pub-id>
          <pub-id pub-id-type="pii">10.1186/s12890-016-0288-z</pub-id>
          <pub-id pub-id-type="pmcid">PMC4994273</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref57">
        <label>57</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Cox</surname>
              <given-names>NS</given-names>
            </name>
            <name name-style="western">
              <surname>McDonald</surname>
              <given-names>CF</given-names>
            </name>
            <name name-style="western">
              <surname>Alison</surname>
              <given-names>JA</given-names>
            </name>
            <name name-style="western">
              <surname>Mahal</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Wootton</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Hill</surname>
              <given-names>CJ</given-names>
            </name>
            <name name-style="western">
              <surname>Bondarenko</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Macdonald</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>O'Halloran</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Zanaboni</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Clarke</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Rennick</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Borgelt</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Burge</surname>
              <given-names>AT</given-names>
            </name>
            <name name-style="western">
              <surname>Lahham</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Wageck</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Crute</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Czupryn</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Nichols</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Holland</surname>
              <given-names>AE</given-names>
            </name>
          </person-group>
          <article-title>Telerehabilitation versus traditional centre-based pulmonary rehabilitation for people with chronic respiratory disease: protocol for a randomised controlled trial</article-title>
          <source>BMC Pulm Med</source>
          <year>2018</year>
          <month>05</month>
          <day>15</day>
          <volume>18</volume>
          <issue>1</issue>
          <fpage>71</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://bmcpulmmed.biomedcentral.com/articles/10.1186/s12890-018-0646-0"/>
          </comment>
          <pub-id pub-id-type="doi">10.1186/s12890-018-0646-0</pub-id>
          <pub-id pub-id-type="medline">29764393</pub-id>
          <pub-id pub-id-type="pii">10.1186/s12890-018-0646-0</pub-id>
          <pub-id pub-id-type="pmcid">PMC5952573</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref58">
        <label>58</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Chen</surname>
              <given-names>AC</given-names>
            </name>
            <name name-style="western">
              <surname>Rosenthal</surname>
              <given-names>DN</given-names>
            </name>
            <name name-style="western">
              <surname>Couch</surname>
              <given-names>SC</given-names>
            </name>
            <name name-style="western">
              <surname>Berry</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Stauffer</surname>
              <given-names>KJ</given-names>
            </name>
            <name name-style="western">
              <surname>Brabender</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>McDonald</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Lee</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Barkoff</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Nourse</surname>
              <given-names>SE</given-names>
            </name>
            <name name-style="western">
              <surname>Kazmucha</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Wang</surname>
              <given-names>CJ</given-names>
            </name>
            <name name-style="western">
              <surname>Olson</surname>
              <given-names>I</given-names>
            </name>
            <name name-style="western">
              <surname>Tierney</surname>
              <given-names>ES</given-names>
            </name>
          </person-group>
          <article-title>Healthy hearts in pediatric heart transplant patients with an exercise and diet intervention via live video conferencing-design and rationale</article-title>
          <source>Pediatr Transplant</source>
          <year>2019</year>
          <month>02</month>
          <volume>23</volume>
          <issue>1</issue>
          <fpage>e13316</fpage>
          <pub-id pub-id-type="doi">10.1111/petr.13316</pub-id>
          <pub-id pub-id-type="medline">30393915</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref59">
        <label>59</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Vincze</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Rollo</surname>
              <given-names>ME</given-names>
            </name>
            <name name-style="western">
              <surname>Hutchesson</surname>
              <given-names>MJ</given-names>
            </name>
            <name name-style="western">
              <surname>Callister</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Collins</surname>
              <given-names>CE</given-names>
            </name>
          </person-group>
          <article-title>VITAL change for mums: a feasibility study investigating tailored nutrition and exercise care delivered by video-consultations for women 3-12 months postpartum</article-title>
          <source>J Hum Nutr Diet</source>
          <year>2018</year>
          <month>06</month>
          <volume>31</volume>
          <issue>3</issue>
          <fpage>337</fpage>
          <lpage>48</lpage>
          <pub-id pub-id-type="doi">10.1111/jhn.12549</pub-id>
          <pub-id pub-id-type="medline">29543356</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref60">
        <label>60</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Marhefka</surname>
              <given-names>SL</given-names>
            </name>
            <name name-style="western">
              <surname>Turner</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Lockhart</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Rivara</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Wang</surname>
              <given-names>W</given-names>
            </name>
            <name name-style="western">
              <surname>Shuter</surname>
              <given-names>J</given-names>
            </name>
          </person-group>
          <article-title>Meeting our patients 'where they are': video-group smoking cessation for people living with HIV</article-title>
          <source>J Assoc Nurses AIDS Care</source>
          <year>2018</year>
          <volume>29</volume>
          <issue>2</issue>
          <fpage>338</fpage>
          <lpage>44</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/29033093"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/j.jana.2017.09.007</pub-id>
          <pub-id pub-id-type="medline">29033093</pub-id>
          <pub-id pub-id-type="pii">S1055-3290(17)30235-2</pub-id>
          <pub-id pub-id-type="pmcid">PMC5816712</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref61">
        <label>61</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Coles</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Patel</surname>
              <given-names>BP</given-names>
            </name>
            <name name-style="western">
              <surname>Li</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Cordeiro</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Steinberg</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Zdravkovic</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Hamilton</surname>
              <given-names>JK</given-names>
            </name>
          </person-group>
          <article-title>Breaking barriers: adjunctive use of the Ontario telemedicine network (OTN) to reach adolescents with obesity living in remote locations</article-title>
          <source>J Telemed Telecare</source>
          <year>2020</year>
          <month>06</month>
          <volume>26</volume>
          <issue>5</issue>
          <fpage>271</fpage>
          <lpage>7</lpage>
          <pub-id pub-id-type="doi">10.1177/1357633X18816254</pub-id>
          <pub-id pub-id-type="medline">30526258</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref62">
        <label>62</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Onezi</surname>
              <given-names>HA</given-names>
            </name>
            <name name-style="western">
              <surname>Khalifa</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>El-Metwally</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Househ</surname>
              <given-names>M</given-names>
            </name>
          </person-group>
          <article-title>The impact of social media-based support groups on smoking relapse prevention in Saudi Arabia</article-title>
          <source>Comput Methods Programs Biomed</source>
          <year>2018</year>
          <month>06</month>
          <volume>159</volume>
          <fpage>135</fpage>
          <lpage>43</lpage>
          <pub-id pub-id-type="doi">10.1016/j.cmpb.2018.03.005</pub-id>
          <pub-id pub-id-type="medline">29650308</pub-id>
          <pub-id pub-id-type="pii">S0169-2607(18)30059-2</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref63">
        <label>63</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Fleischman</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Hourigan</surname>
              <given-names>SE</given-names>
            </name>
            <name name-style="western">
              <surname>Lyon</surname>
              <given-names>HN</given-names>
            </name>
            <name name-style="western">
              <surname>Landry</surname>
              <given-names>MG</given-names>
            </name>
            <name name-style="western">
              <surname>Reynolds</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Steltz</surname>
              <given-names>SK</given-names>
            </name>
            <name name-style="western">
              <surname>Robinson</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Keating</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Feldman</surname>
              <given-names>HA</given-names>
            </name>
            <name name-style="western">
              <surname>Antonelli</surname>
              <given-names>RC</given-names>
            </name>
            <name name-style="western">
              <surname>Ludwig</surname>
              <given-names>DS</given-names>
            </name>
            <name name-style="western">
              <surname>Ebbeling</surname>
              <given-names>CB</given-names>
            </name>
          </person-group>
          <article-title>Creating an integrated care model for childhood obesity: a randomized pilot study utilizing telehealth in a community primary care setting</article-title>
          <source>Clin Obes</source>
          <year>2016</year>
          <month>12</month>
          <volume>6</volume>
          <issue>6</issue>
          <fpage>380</fpage>
          <lpage>8</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/27863024"/>
          </comment>
          <pub-id pub-id-type="doi">10.1111/cob.12166</pub-id>
          <pub-id pub-id-type="medline">27863024</pub-id>
          <pub-id pub-id-type="pmcid">PMC5523655</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref64">
        <label>64</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>van Straaten</surname>
              <given-names>MG</given-names>
            </name>
            <name name-style="western">
              <surname>Cloud</surname>
              <given-names>BA</given-names>
            </name>
            <name name-style="western">
              <surname>Morrow</surname>
              <given-names>MM</given-names>
            </name>
            <name name-style="western">
              <surname>Ludewig</surname>
              <given-names>PM</given-names>
            </name>
            <name name-style="western">
              <surname>Zhao</surname>
              <given-names>KD</given-names>
            </name>
          </person-group>
          <article-title>Effectiveness of home exercise on pain, function, and strength of manual wheelchair users with spinal cord injury: a high-dose shoulder program with telerehabilitation</article-title>
          <source>Arch Phys Med Rehabil</source>
          <year>2014</year>
          <month>10</month>
          <volume>95</volume>
          <issue>10</issue>
          <fpage>1810</fpage>
          <lpage>7.e2</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/24887534"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/j.apmr.2014.05.004</pub-id>
          <pub-id pub-id-type="medline">24887534</pub-id>
          <pub-id pub-id-type="pii">S0003-9993(14)00391-8</pub-id>
          <pub-id pub-id-type="pmcid">PMC4182115</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref65">
        <label>65</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Frueh</surname>
              <given-names>BC</given-names>
            </name>
            <name name-style="western">
              <surname>Henderson</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Myrick</surname>
              <given-names>H</given-names>
            </name>
          </person-group>
          <article-title>Telehealth service delivery for persons with alcoholism</article-title>
          <source>J Telemed Telecare</source>
          <year>2005</year>
          <volume>11</volume>
          <issue>7</issue>
          <fpage>372</fpage>
          <lpage>5</lpage>
          <pub-id pub-id-type="doi">10.1258/135763305774472060</pub-id>
          <pub-id pub-id-type="medline">16238840</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref66">
        <label>66</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Byaruhanga</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Tzelepis</surname>
              <given-names>F</given-names>
            </name>
            <name name-style="western">
              <surname>Paul</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Wiggers</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Byrnes</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Bowman</surname>
              <given-names>J</given-names>
            </name>
          </person-group>
          <article-title>The short-term effectiveness of real-time video counseling on smoking cessation among smokers residing in regional and remote areas</article-title>
          <source>J Clin Oncol</source>
          <year>2018</year>
          <volume>2017</volume>
          <issue>5</issue>
          <fpage>-</fpage>
          <pub-id pub-id-type="doi">10.1002/14651858.CD012659</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref67">
        <label>67</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Parameswaran</surname>
              <given-names>V</given-names>
            </name>
            <name name-style="western">
              <surname>Josan</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Winterbottom</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Shearer</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Khandelwal</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Nallamshetty</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Dash</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Rodriguez</surname>
              <given-names>F</given-names>
            </name>
          </person-group>
          <article-title>Abstract P337: cardioclick an innovative telehealth approach to lifestyle intervention in high risk south Asians</article-title>
          <source>Circulation</source>
          <year>2019</year>
          <month>03</month>
          <day>05</day>
          <volume>139</volume>
          <issue>Suppl_1</issue>
          <fpage>-</fpage>
          <pub-id pub-id-type="doi">10.1161/circ.139.suppl_1.p337</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref68">
        <label>68</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Alencar</surname>
              <given-names>MK</given-names>
            </name>
            <name name-style="western">
              <surname>Johnson</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Mullur</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Gray</surname>
              <given-names>V</given-names>
            </name>
            <name name-style="western">
              <surname>Gutierrez</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Korosteleva</surname>
              <given-names>O</given-names>
            </name>
          </person-group>
          <article-title>The efficacy of a telemedicine-based weight loss program with video conference health coaching support</article-title>
          <source>J Telemed Telecare</source>
          <year>2019</year>
          <month>04</month>
          <volume>25</volume>
          <issue>3</issue>
          <fpage>151</fpage>
          <lpage>7</lpage>
          <pub-id pub-id-type="doi">10.1177/1357633X17745471</pub-id>
          <pub-id pub-id-type="medline">29199544</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref69">
        <label>69</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Alencar</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Johnson</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Gray</surname>
              <given-names>V</given-names>
            </name>
            <name name-style="western">
              <surname>Mullur</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Gutierrez</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Dionico</surname>
              <given-names>P</given-names>
            </name>
          </person-group>
          <article-title>Telehealth-based health coaching increases m-health device adherence and rate of weight loss in obese participants</article-title>
          <source>Telemed J E Health</source>
          <year>2020</year>
          <month>03</month>
          <volume>26</volume>
          <issue>3</issue>
          <fpage>365</fpage>
          <lpage>8</lpage>
          <pub-id pub-id-type="doi">10.1089/tmj.2019.0017</pub-id>
          <pub-id pub-id-type="medline">30994410</pub-id>
          <pub-id pub-id-type="pmcid">PMC7071022</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref70">
        <label>70</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Kim</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Sitthisongkram</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Bernstein</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Fang</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Choi</surname>
              <given-names>W</given-names>
            </name>
            <name name-style="western">
              <surname>Ziedonis</surname>
              <given-names>D</given-names>
            </name>
          </person-group>
          <article-title>A randomized controlled trial of a videoconferencing smoking cessation intervention for Korean American women: preliminary findings</article-title>
          <source>Int J Womens Health</source>
          <year>2016</year>
          <volume>8</volume>
          <fpage>453</fpage>
          <lpage>62</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://dx.doi.org/10.2147/IJWH.S109819"/>
          </comment>
          <pub-id pub-id-type="doi">10.2147/IJWH.S109819</pub-id>
          <pub-id pub-id-type="medline">27660494</pub-id>
          <pub-id pub-id-type="pii">ijwh-8-453</pub-id>
          <pub-id pub-id-type="pmcid">PMC5019447</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref71">
        <label>71</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Kim</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Darwish</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Lee</surname>
              <given-names>SA</given-names>
            </name>
            <name name-style="western">
              <surname>Sprague</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>DeMarco</surname>
              <given-names>RF</given-names>
            </name>
          </person-group>
          <article-title>A randomized controlled pilot trial of a smoking cessation intervention for US women living with HIV: telephone-based video call vs voice call</article-title>
          <source>Int J Womens Health</source>
          <year>2018</year>
          <volume>10</volume>
          <fpage>545</fpage>
          <lpage>55</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://dx.doi.org/10.2147/IJWH.S172669"/>
          </comment>
          <pub-id pub-id-type="doi">10.2147/IJWH.S172669</pub-id>
          <pub-id pub-id-type="medline">30288127</pub-id>
          <pub-id pub-id-type="pii">ijwh-10-545</pub-id>
          <pub-id pub-id-type="pmcid">PMC6161719</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref72">
        <label>72</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Nomura</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Tanigawa</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Muto</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Oga</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Fukushima</surname>
              <given-names>Y</given-names>
            </name>
            <name name-style="western">
              <surname>Kiyosue</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Miyazaki</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Hida</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Satake</surname>
              <given-names>K</given-names>
            </name>
          </person-group>
          <article-title>Clinical efficacy of telemedicine compared to face-to-face clinic visits for smoking cessation: multicenter open-label randomized controlled noninferiority trial</article-title>
          <source>J Med Internet Res</source>
          <year>2019</year>
          <month>04</month>
          <day>26</day>
          <volume>21</volume>
          <issue>4</issue>
          <fpage>e13520</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.jmir.org/2019/4/e13520/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/13520</pub-id>
          <pub-id pub-id-type="medline">30982776</pub-id>
          <pub-id pub-id-type="pii">v21i4e13520</pub-id>
          <pub-id pub-id-type="pmcid">PMC6660118</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref73">
        <label>73</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Tarp</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Bojesen</surname>
              <given-names>AB</given-names>
            </name>
            <name name-style="western">
              <surname>Mejldal</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Nielsen</surname>
              <given-names>AS</given-names>
            </name>
          </person-group>
          <article-title>Effectiveness of optional videoconferencing-based treatment of alcohol use disorders: randomized controlled trial</article-title>
          <source>JMIR Ment Health</source>
          <year>2017</year>
          <month>09</month>
          <day>29</day>
          <volume>4</volume>
          <issue>3</issue>
          <fpage>e38</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://mental.jmir.org/2017/3/e38/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/mental.6713</pub-id>
          <pub-id pub-id-type="medline">28963093</pub-id>
          <pub-id pub-id-type="pii">v4i3e38</pub-id>
          <pub-id pub-id-type="pmcid">PMC5640821</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref74">
        <label>74</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Staton-Tindall</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Havens</surname>
              <given-names>JR</given-names>
            </name>
            <name name-style="western">
              <surname>Webster</surname>
              <given-names>JM</given-names>
            </name>
            <name name-style="western">
              <surname>Leukefeld</surname>
              <given-names>C</given-names>
            </name>
          </person-group>
          <article-title>METelemedicine: a pilot study with rural alcohol users on community supervision</article-title>
          <source>J Rural Health</source>
          <year>2014</year>
          <volume>30</volume>
          <issue>4</issue>
          <fpage>422</fpage>
          <lpage>32</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/24800699"/>
          </comment>
          <pub-id pub-id-type="doi">10.1111/jrh.12076</pub-id>
          <pub-id pub-id-type="medline">24800699</pub-id>
          <pub-id pub-id-type="pmcid">PMC5024736</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref75">
        <label>75</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>King</surname>
              <given-names>SC</given-names>
            </name>
            <name name-style="western">
              <surname>Richner</surname>
              <given-names>KA</given-names>
            </name>
            <name name-style="western">
              <surname>Tuliao</surname>
              <given-names>AP</given-names>
            </name>
            <name name-style="western">
              <surname>Kennedy</surname>
              <given-names>JL</given-names>
            </name>
            <name name-style="western">
              <surname>McChargue</surname>
              <given-names>DE</given-names>
            </name>
          </person-group>
          <article-title>A comparison between telehealth and face-to-face delivery of a brief alcohol intervention for college students</article-title>
          <source>Subst Abus</source>
          <year>2019</year>
          <month>10</month>
          <day>23</day>
          <fpage>1</fpage>
          <lpage>9</lpage>
          <comment>epub ahead of print</comment>
          <pub-id pub-id-type="doi">10.1080/08897077.2019.1675116</pub-id>
          <pub-id pub-id-type="medline">31644389</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref76">
        <label>76</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Alley</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Jennings</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Plotnikoff</surname>
              <given-names>RC</given-names>
            </name>
            <name name-style="western">
              <surname>Vandelanotte</surname>
              <given-names>C</given-names>
            </name>
          </person-group>
          <article-title>Web-based video-coaching to assist an automated computer-tailored physical activity intervention for inactive adults: a randomized controlled trial</article-title>
          <source>J Med Internet Res</source>
          <year>2016</year>
          <month>08</month>
          <day>12</day>
          <volume>18</volume>
          <issue>8</issue>
          <fpage>e223</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.jmir.org/2016/8/e223/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/jmir.5664</pub-id>
          <pub-id pub-id-type="medline">27520283</pub-id>
          <pub-id pub-id-type="pii">v18i8e223</pub-id>
          <pub-id pub-id-type="pmcid">PMC5002066</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref77">
        <label>77</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Weinstock</surname>
              <given-names>RS</given-names>
            </name>
            <name name-style="western">
              <surname>Brooks</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Palmas</surname>
              <given-names>W</given-names>
            </name>
            <name name-style="western">
              <surname>Morin</surname>
              <given-names>PC</given-names>
            </name>
            <name name-style="western">
              <surname>Teresi</surname>
              <given-names>JA</given-names>
            </name>
            <name name-style="western">
              <surname>Eimicke</surname>
              <given-names>JP</given-names>
            </name>
            <name name-style="western">
              <surname>Silver</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Izquierdo</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Goland</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Shea</surname>
              <given-names>S</given-names>
            </name>
          </person-group>
          <article-title>Lessened decline in physical activity and impairment of older adults with diabetes with telemedicine and pedometer use: results from the IDEATel study</article-title>
          <source>Age Ageing</source>
          <year>2011</year>
          <month>01</month>
          <volume>40</volume>
          <issue>1</issue>
          <fpage>98</fpage>
          <lpage>105</lpage>
          <pub-id pub-id-type="doi">10.1093/ageing/afq147</pub-id>
          <pub-id pub-id-type="medline">21081539</pub-id>
          <pub-id pub-id-type="pii">afq147</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref78">
        <label>78</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Chemtob</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Rocchi</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Arbour-Nicitopoulos</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Kairy</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Fillion</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Sweet</surname>
              <given-names>S</given-names>
            </name>
          </person-group>
          <article-title>Using tele-health to enhance motivation, leisure time physical activity, and quality of life in adults with spinal cord injury: A self-determination theory-based pilot randomized control trial</article-title>
          <source>Psychol Sport Exerc</source>
          <year>2019</year>
          <month>07</month>
          <volume>43</volume>
          <fpage>243</fpage>
          <lpage>52</lpage>
          <pub-id pub-id-type="doi">10.1016/j.psychsport.2019.03.008</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref79">
        <label>79</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Hansen</surname>
              <given-names>CR</given-names>
            </name>
            <name name-style="western">
              <surname>Perrild</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Koefoed</surname>
              <given-names>BG</given-names>
            </name>
            <name name-style="western">
              <surname>Zander</surname>
              <given-names>M</given-names>
            </name>
          </person-group>
          <article-title>Video consultations as add-on to standard care among patients with type 2 diabetes not responding to standard regimens: a randomized controlled trial</article-title>
          <source>Eur J Endocrinol</source>
          <year>2017</year>
          <month>06</month>
          <volume>176</volume>
          <issue>6</issue>
          <fpage>727</fpage>
          <lpage>36</lpage>
          <pub-id pub-id-type="doi">10.1530/EJE-16-0811</pub-id>
          <pub-id pub-id-type="medline">28325823</pub-id>
          <pub-id pub-id-type="pii">EJE160811</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref80">
        <label>80</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Homma</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Imamura</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Nakamura</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Fujimura</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Ito</surname>
              <given-names>Y</given-names>
            </name>
            <name name-style="western">
              <surname>Maeda</surname>
              <given-names>Y</given-names>
            </name>
            <name name-style="western">
              <surname>Kaneko</surname>
              <given-names>I</given-names>
            </name>
          </person-group>
          <article-title>A comparative study on the effectiveness of one-way printed communication versus videophone interactive interviews on health promotion</article-title>
          <source>J Telemed Telecare</source>
          <year>2016</year>
          <month>01</month>
          <volume>22</volume>
          <issue>1</issue>
          <fpage>56</fpage>
          <lpage>63</lpage>
          <pub-id pub-id-type="doi">10.1177/1357633X15587436</pub-id>
          <pub-id pub-id-type="medline">26026183</pub-id>
          <pub-id pub-id-type="pii">1357633X15587436</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref81">
        <label>81</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Johnson</surname>
              <given-names>KE</given-names>
            </name>
            <name name-style="western">
              <surname>Alencar</surname>
              <given-names>MK</given-names>
            </name>
            <name name-style="western">
              <surname>Coakley</surname>
              <given-names>KE</given-names>
            </name>
            <name name-style="western">
              <surname>Swift</surname>
              <given-names>DL</given-names>
            </name>
            <name name-style="western">
              <surname>Cole</surname>
              <given-names>NH</given-names>
            </name>
            <name name-style="western">
              <surname>Mermier</surname>
              <given-names>CM</given-names>
            </name>
            <name name-style="western">
              <surname>Kravitz</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Amorim</surname>
              <given-names>FT</given-names>
            </name>
            <name name-style="western">
              <surname>Gibson</surname>
              <given-names>AL</given-names>
            </name>
          </person-group>
          <article-title>Telemedicine-based health coaching is effective for inducing weight loss and improving metabolic markers</article-title>
          <source>Telemed J E Health</source>
          <year>2019</year>
          <month>02</month>
          <volume>25</volume>
          <issue>2</issue>
          <fpage>85</fpage>
          <lpage>92</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/29847222"/>
          </comment>
          <pub-id pub-id-type="doi">10.1089/tmj.2018.0002</pub-id>
          <pub-id pub-id-type="medline">29847222</pub-id>
          <pub-id pub-id-type="pmcid">PMC6384514</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref82">
        <label>82</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Cunningham</surname>
              <given-names>JA</given-names>
            </name>
            <name name-style="western">
              <surname>Kypri</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>McCambridge</surname>
              <given-names>J</given-names>
            </name>
          </person-group>
          <article-title>The use of emerging technologies in alcohol treatment</article-title>
          <source>Alcohol Res Health</source>
          <year>2011</year>
          <volume>33</volume>
          <issue>4</issue>
          <fpage>320</fpage>
          <lpage>6</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/23580017"/>
          </comment>
          <pub-id pub-id-type="medline">23580017</pub-id>
          <pub-id pub-id-type="pmcid">PMC3860543</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref83">
        <label>83</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Fleming</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Manwell</surname>
              <given-names>LB</given-names>
            </name>
          </person-group>
          <article-title>Brief intervention in primary care settings. A primary treatment method for at-risk, problem, and dependent drinkers</article-title>
          <source>Alcohol Res Health</source>
          <year>1999</year>
          <volume>23</volume>
          <issue>2</issue>
          <fpage>128</fpage>
          <lpage>37</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/10890807"/>
          </comment>
          <pub-id pub-id-type="medline">10890807</pub-id>
          <pub-id pub-id-type="pmcid">PMC6760420</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref84">
        <label>84</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Boutron</surname>
              <given-names>I</given-names>
            </name>
            <name name-style="western">
              <surname>Tubach</surname>
              <given-names>F</given-names>
            </name>
            <name name-style="western">
              <surname>Giraudeau</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Ravaud</surname>
              <given-names>P</given-names>
            </name>
          </person-group>
          <article-title>Blinding was judged more difficult to achieve and maintain in nonpharmacologic than pharmacologic trials</article-title>
          <source>J Clin Epidemiol</source>
          <year>2004</year>
          <month>07</month>
          <volume>57</volume>
          <issue>6</issue>
          <fpage>543</fpage>
          <lpage>50</lpage>
          <pub-id pub-id-type="doi">10.1016/j.jclinepi.2003.12.010</pub-id>
          <pub-id pub-id-type="medline">15246122</pub-id>
          <pub-id pub-id-type="pii">S0895435604000204</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref85">
        <label>85</label>
        <nlm-citation citation-type="web">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Greenhalgh</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Stillman</surname>
              <given-names>S</given-names>
            </name>
          </person-group>
          <article-title>Cessation Assistance: Telephone- and Internet-based Interventions</article-title>
          <source>Tobacco in Australia</source>
          <year>2020</year>
          <access-date>2020-09-02</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.tobaccoinaustralia.org.au/chapter-7-cessation/7-14-methods-services-and-products-for-quitting-te">https://www.tobaccoinaustralia.org.au/chapter-7-cessation/7-14-methods-services-and-products-for-quitting-te</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref86">
        <label>86</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Ossip-Klein</surname>
              <given-names>DJ</given-names>
            </name>
            <name name-style="western">
              <surname>McIntosh</surname>
              <given-names>S</given-names>
            </name>
          </person-group>
          <article-title>Quitlines in North America: evidence base and applications</article-title>
          <source>Am J Med Sci</source>
          <year>2003</year>
          <month>10</month>
          <volume>326</volume>
          <issue>4</issue>
          <fpage>201</fpage>
          <lpage>5</lpage>
          <pub-id pub-id-type="doi">10.1097/00000441-200310000-00010</pub-id>
          <pub-id pub-id-type="medline">14557735</pub-id>
          <pub-id pub-id-type="pii">S0002-9629(15)34199-9</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref87">
        <label>87</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Molfenter</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Boyle</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Holloway</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Zwick</surname>
              <given-names>J</given-names>
            </name>
          </person-group>
          <article-title>Trends in telemedicine use in addiction treatment</article-title>
          <source>Addict Sci Clin Pract</source>
          <year>2015</year>
          <month>05</month>
          <day>28</day>
          <volume>10</volume>
          <fpage>14</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://ascpjournal.biomedcentral.com/articles/10.1186/s13722-015-0035-4"/>
          </comment>
          <pub-id pub-id-type="doi">10.1186/s13722-015-0035-4</pub-id>
          <pub-id pub-id-type="medline">26016484</pub-id>
          <pub-id pub-id-type="pii">10.1186/s13722-015-0035-4</pub-id>
          <pub-id pub-id-type="pmcid">PMC4636787</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref88">
        <label>88</label>
        <nlm-citation citation-type="book">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Sterne</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Egger</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Moher</surname>
              <given-names>D</given-names>
            </name>
          </person-group>
          <source>Addressing Reporting Biases. Cochrane Handbook for Systematic Reviews of Intervention. Version 5.1</source>
          <year>2011</year>
          <publisher-loc>Chichester, UK</publisher-loc>
          <publisher-name>Cochrane Collaboration</publisher-name>
        </nlm-citation>
      </ref>
      <ref id="ref89">
        <label>89</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Ignatowicz</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Atherton</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Bernstein</surname>
              <given-names>CJ</given-names>
            </name>
            <name name-style="western">
              <surname>Bryce</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Court</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Sturt</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Griffiths</surname>
              <given-names>F</given-names>
            </name>
          </person-group>
          <article-title>Internet videoconferencing for patient-clinician consultations in long-term conditions: a review of reviews and applications in line with guidelines and recommendations</article-title>
          <source>Digit Health</source>
          <year>2019</year>
          <volume>5</volume>
          <fpage>2055207619845831</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://journals.sagepub.com/doi/10.1177/2055207619845831?url_ver=Z39.88-2003&#38;rfr_id=ori:rid:crossref.org&#38;rfr_dat=cr_pub%3dpubmed"/>
          </comment>
          <pub-id pub-id-type="doi">10.1177/2055207619845831</pub-id>
          <pub-id pub-id-type="medline">31069105</pub-id>
          <pub-id pub-id-type="pii">10.1177_2055207619845831</pub-id>
          <pub-id pub-id-type="pmcid">PMC6495459</pub-id>
        </nlm-citation>
      </ref>
    </ref-list>
  </back>
</article>
