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<?covid-19-tdm?>
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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JMIR</journal-id>
      <journal-id journal-id-type="nlm-ta">J Med Internet Res</journal-id>
      <journal-title>Journal of Medical Internet Research</journal-title>
      <issn pub-type="epub">1438-8871</issn>
      <publisher>
        <publisher-name>JMIR Publications</publisher-name>
        <publisher-loc>Toronto, Canada</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">v22i5e19577</article-id>
      <article-id pub-id-type="pmid">32349962</article-id>
      <article-id pub-id-type="doi">10.2196/19577</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Viewpoint</subject>
        </subj-group>
        <subj-group subj-group-type="article-type">
          <subject>Viewpoint</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Telemedicine During the COVID-19 Pandemic: Experiences From Western China</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="editor">
          <name>
            <surname>Eysenbach</surname>
            <given-names>Gunther</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Bahrami</surname>
            <given-names>Mohammad Amin</given-names>
          </name>
        </contrib>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Da Silva</surname>
            <given-names>Edson</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib id="contrib1" contrib-type="author" equal-contrib="yes">
          <name name-style="western">
            <surname>Hong</surname>
            <given-names>Zhen</given-names>
          </name>
          <degrees>PhD, MD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-0014-6873</ext-link>
        </contrib>
        <contrib id="contrib2" contrib-type="author" equal-contrib="yes">
          <name name-style="western">
            <surname>Li</surname>
            <given-names>Nian</given-names>
          </name>
          <degrees>MD</degrees>
          <xref rid="aff2" ref-type="aff">2</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0003-3253-2565</ext-link>
        </contrib>
        <contrib id="contrib3" contrib-type="author">
          <name name-style="western">
            <surname>Li</surname>
            <given-names>Dajiang</given-names>
          </name>
          <degrees>MD</degrees>
          <xref rid="aff2" ref-type="aff">2</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-6931-9955</ext-link>
        </contrib>
        <contrib id="contrib4" contrib-type="author">
          <name name-style="western">
            <surname>Li</surname>
            <given-names>Junhua</given-names>
          </name>
          <degrees>BSc</degrees>
          <xref rid="aff3" ref-type="aff">3</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-5643-3994</ext-link>
        </contrib>
        <contrib id="contrib5" contrib-type="author">
          <name name-style="western">
            <surname>Li</surname>
            <given-names>Bing</given-names>
          </name>
          <degrees>BSc</degrees>
          <xref rid="aff3" ref-type="aff">3</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-4208-3014</ext-link>
        </contrib>
        <contrib id="contrib6" contrib-type="author">
          <name name-style="western">
            <surname>Xiong</surname>
            <given-names>Weixi</given-names>
          </name>
          <degrees>MD, PhD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0001-6835-8664</ext-link>
        </contrib>
        <contrib id="contrib7" contrib-type="author">
          <name name-style="western">
            <surname>Lu</surname>
            <given-names>Lu</given-names>
          </name>
          <degrees>MD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0003-3717-5237</ext-link>
        </contrib>
        <contrib id="contrib8" contrib-type="author">
          <name name-style="western">
            <surname>Li</surname>
            <given-names>Weimin</given-names>
          </name>
          <degrees>MD</degrees>
          <xref rid="aff4" ref-type="aff">4</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0003-0985-0311</ext-link>
        </contrib>
        <contrib id="contrib9" contrib-type="author" corresp="yes">
          <name name-style="western">
            <surname>Zhou</surname>
            <given-names>Dong</given-names>
          </name>
          <degrees>MD, PhD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <address>
            <institution>Department of Neurology</institution>
            <institution>West China Hospital</institution>
            <institution>Sichuan University</institution>
            <addr-line>No. 37 Guoxue Road</addr-line>
            <addr-line>Chengdu, 610041</addr-line>
            <country>China</country>
            <phone>86 28 8542 2893</phone>
            <email>zhoudong66@yahoo.de</email>
          </address>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0001-7101-4125</ext-link>
        </contrib>
      </contrib-group>
      <aff id="aff1">
        <label>1</label>
        <institution>Department of Neurology</institution>
        <institution>West China Hospital</institution>
        <institution>Sichuan University</institution>
        <addr-line>Chengdu</addr-line>
        <country>China</country>
      </aff>
      <aff id="aff2">
        <label>2</label>
        <institution>Department of Medical Affairs, West China Hospital, Sichuan University</institution>
        <addr-line>Chengdu</addr-line>
        <country>China</country>
      </aff>
      <aff id="aff3">
        <label>3</label>
        <institution>Medical Administration, Health Commission of Sichuan Province</institution>
        <addr-line>Chengdu</addr-line>
        <country>China</country>
      </aff>
      <aff id="aff4">
        <label>4</label>
        <institution>Department of Pulmonary and Critical Care Medicine</institution>
        <institution>West China Hospital</institution>
        <institution>Sichuan University</institution>
        <addr-line>Chengdu</addr-line>
        <country>China</country>
      </aff>
      <author-notes>
        <corresp>Corresponding Author: Dong Zhou <email>zhoudong66@yahoo.de</email></corresp>
      </author-notes>
      <pub-date pub-type="collection">
        <month>5</month>
        <year>2020</year>
      </pub-date>
      <pub-date pub-type="epub">
        <day>8</day>
        <month>5</month>
        <year>2020</year>
      </pub-date>
      <volume>22</volume>
      <issue>5</issue>
      <elocation-id>e19577</elocation-id>
      <history>
        <date date-type="received">
          <day>23</day>
          <month>4</month>
          <year>2020</year>
        </date>
        <date date-type="accepted">
          <day>29</day>
          <month>4</month>
          <year>2020</year>
        </date>
      </history>
      <copyright-statement>©Zhen Hong, Nian Li, Dajiang Li, Junhua Li, Bing Li, Weixi Xiong, Lu Lu, Weimin Li, Dong Zhou. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 08.05.2020.</copyright-statement>
      <copyright-year>2020</copyright-year>
      <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
        <p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Journal of Medical Internet Research, is properly cited. The complete bibliographic information, a link to the original publication on http://www.jmir.org/, as well as this copyright and license information must be included.</p>
      </license>
      <self-uri xlink:href="http://www.jmir.org/2020/5/e19577/" xlink:type="simple"/>
      <abstract>
        <p>Disasters and pandemics pose unique challenges to health care delivery. As health care resources continue to be stretched due to the increasing burden of the coronavirus disease (COVID-19) pandemic, telemedicine, including tele-education, may be an effective way to rationally allocate medical resources. During the COVID-19 pandemic, a multimodal telemedicine network in Sichuan Province in Western China was activated immediately after the first outbreak in January 2020. The network synergizes a newly established 5G service, a smartphone app, and an existing telemedicine system. Telemedicine was demonstrated to be feasible, acceptable, and effective in Western China, and allowed for significant improvements in health care outcomes. The success of telemedicine here may be a useful reference for other parts of the world.</p>
      </abstract>
      <kwd-group>
        <kwd>COVID-19</kwd>
        <kwd>coronavirus disease</kwd>
        <kwd>medical education</kwd>
        <kwd>pandemics</kwd>
        <kwd>teleteaching</kwd>
        <kwd>tele-education</kwd>
        <kwd>telemedicine</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec sec-type="introduction">
      <title>Introduction</title>
      <p>Coronavirus disease (COVID-19) has been declared a pandemic by the World Health Organization (WHO), whose director-general expressed concerns about the “alarming spread and severity” as well as the “alarming levels of inaction” [<xref ref-type="bibr" rid="ref1">1</xref>]. Although the outbreaks of severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS) were associated with much higher respective case fatality rates (CFRs of 9.6% and 34.4%, respectively), the COVID-19 pandemic has led to more deaths due to the large number of individuals infected. Human-to-human transmission of the SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) virus has become the primary transmission route of the disease [<xref ref-type="bibr" rid="ref2">2</xref>]. In this context, policymakers need to weigh the risks of inaction and pursue policies and strategies commensurate with the magnitude of the threat.</p>
      <p>Pandemics and other public health emergencies typically lead to a surge in demand for medical care, which overwhelms local capabilities. Telemedicine can be broadly defined as the use of telecommunications technologies to provide medical information and services. The benefits of telemedicine in these situations have been well documented [<xref ref-type="bibr" rid="ref3">3</xref>,<xref ref-type="bibr" rid="ref4">4</xref>]. Telemedicine can support long-distance clinical care, education, and health administration, and its use has increased dramatically in the past decade.</p>
      <p>There are a number of potential benefits to implementing telemedicine, including [<xref ref-type="bibr" rid="ref5">5</xref>]:</p>
      <list list-type="bullet">
        <list-item>
          <p>Improved access to information;</p>
        </list-item>
        <list-item>
          <p>Provision of care not previously deliverable;</p>
        </list-item>
        <list-item>
          <p>Improved access to services and increasing care delivery;</p>
        </list-item>
        <list-item>
          <p>Improved professional education;</p>
        </list-item>
        <list-item>
          <p>Quality control of screening programs;</p>
        </list-item>
        <list-item>
          <p>Reduced health care costs.</p>
        </list-item>
      </list>
      <p>Western China does not have nearly as many economic resources or health care infrastructure as the eastern parts of the country. High-quality medical resources are concentrated in large- and medium-sized cities, and many county- and district-level hospitals face shortages of qualified personnel and inadequate technology for diagnosis and treatment [<xref ref-type="bibr" rid="ref6">6</xref>]. Here, we share experiences of a multimodal telemedicine network in Sichuan Province in Western China during the COVID-19 pandemic. The network synergizes a newly established 5G service, a smartphone app, and an existing telemedicine system. The Sichuan telemedicine network was activated immediately after the first COVID-19 outbreak in January 2020 (<xref rid="figure1" ref-type="fig">Figure 1</xref>). Disaster response funds have been used to pay directly for telehealth care in the short term through a contingency contract with a telehealth network. It capitalized on the remote capabilities of staff and technology and likely played an important role during the pandemic.</p>
      <fig id="figure1" position="float">
        <label>Figure 1</label>
        <caption>
          <p>Progression of telemedicine in Western China during the coronavirus disease (COVID-19) pandemic. Left: timeline of COVID-19 events since the first case was reported on December 8, 2019. Right: timeline of telemedicine milestones in Sichuan Province of Western China during the COVID-19 pandemic. WHO: World Health Organization.</p>
        </caption>
        <graphic xlink:href="jmir_v22i5e19577_fig1.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
      </fig>
    </sec>
    <sec>
      <title>Tele-Education of Medical Staff About COVID-19</title>
      <p>On January 17, 2020, an expert group for rapid response to COVID-19 was established in Sichuan Province; the experts provided tele-education to medical staff at local hospitals via remote consultation networks, portals, and smartphone apps. So far, more than 800,000 person-times have been devoted to training, helping to ensure the implementation of prevention and control measures against epidemics. Training topics include specimen collection methods, laboratory assays of nucleic acids, standardized diagnosis and treatment, prevention and control of hospital infections, personal protection, and medical waste disposal.</p>
    </sec>
    <sec>
      <title>A 5G Dual Gigabit Network and a Multidisciplinary Medical Team</title>
      <p>On January 26, 2020, the West China Hospital of Sichuan University (WCHSU) launched a new web-based, real-time video telemedicine system for consultations provided by a multidisciplinary team to deal with COVID-19 cases (<xref rid="figure2" ref-type="fig">Figures 2</xref> and <xref rid="figure3" ref-type="fig">3</xref>). The network has focused on groups particularly vulnerable to severe symptoms of COVID-19, including the elderly, pregnant women, children, and patients with chronic health problems. From January 26 to March 12, 2020, 424 remote consultations were conducted for severe and critical COVID-19 patients, whose median age was 64 years (range 35 days to 87 years). Reasons for the consultations included adjustment of a patient’s antiviral therapy (75%), management of complications (68%), adjustment of respiratory therapy (55%), or confirmation of COVID-19 diagnosis (15%).</p>
      <fig id="figure2" position="float">
        <label>Figure 2</label>
        <caption>
          <p>The 5G telemedicine network of Sichuan Province, China, established during the coronavirus disease (COVID-19) pandemic. This system makes use of the newly established China Telecom 5G Dual Gigabit infrastructure and currently covers all designated hospitals for COVID-19 of Sichuan Province (5 provincial-level, 24 municipal-level, and 179 county-level hospitals), with the West China Hospital of Sichuan University (WCHSU) as the central node. The median distance between a spoke hospital and WCHSU is 319 km (range 20 to 1191 km).</p>
        </caption>
        <graphic xlink:href="jmir_v22i5e19577_fig2.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
      </fig>
      <fig id="figure3" position="float">
        <label>Figure 3</label>
        <caption>
          <p>Web-based, real-time video telemedicine for consultations provided by a multidisciplinary team to deal with cases of coronavirus disease (COVID-19) in Western China.</p>
        </caption>
        <graphic xlink:href="jmir_v22i5e19577_fig3.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
      </fig>
      <p>This new COVID-19 telemedicine system may increase diagnostic accuracy of difficult cases and improve treatment of severe or critical cases of COVID-19 for the large rural population of Western China at low cost; it has been highly praised by the WHO. This system may help explain why the CFR of COVID-19 is only 0.55% in Sichuan Province, which is much lower than the 4.64% in Hubei Province, China, and the mean rate of the world so far.</p>
    </sec>
    <sec>
      <title>A 5G Dual Gigabit Network and Remote Computed Tomography Scanning</title>
      <p>On February 24, 2020, radiologists at WCHSU used the 5G Dual Gigabit network to remotely perform computed tomography (CT) on patients with COVID-19 at Ganzi People's Hospital in Ganzi County, Sichuan Province. To our knowledge, this is the first report of remote CT scanning during the COVID-19 pandemic. The experts at WCHSU were able to view the same images and data as the local clinicians at the same time, as well as remotely control the CT equipment at Ganzi People’s Hospital. On March 2, 2020, WCHSU clinicians remotely performed CT scanning of a COVID-19 patient at Huangzhou General Hospital in Huanggang City, Hubei Province. So far, 152 patients at hospitals in the telemedicine network have undergone remote CT scanning under the control and guidance of WCHSU physicians.</p>
      <p>This marks the transition of telemedicine from the traditional “consultation” mode to a “practical operation” mode, ensuring high-quality CT even in areas with severe shortages of qualified technicians.</p>
    </sec>
    <sec>
      <title>COVID-19 Consultations Via Telephone and Internet</title>
      <p>WCHSU officially opened a special COVID-19 telephone hotline and smartphone app for online consultations on January 26, 2020, through which medical staff offer free consultations and psychological interventions. By March 23, 2020, 9085 patients had received online consultations or interventions through the app, and 1094 patients had received consultations or interventions from 137 clinicians by telephone. Among these patients, 293 were screened for suspected COVID-19 and followed up.</p>
    </sec>
    <sec>
      <title>Internet-Based Drug Prescription and Delivery to Patients With Chronic Diseases</title>
      <p>Hospitals are a potential source of COVID-19 cross-infection. To reduce accumulation of people in outpatient clinics during the pandemic, WCHSU and other major Chinese hospitals began to offer online consultations and internet-based drug prescription and delivery service for patients with common and chronic diseases since February 1, 2020. The internet-based services are offered through the hospitals’ websites, WeChat accounts, and widely used apps such as Huayitong. By March 23, 2020, 31,905 patients had received prescriptions or medicines through this service. This telemedicine service reduces the number of patient visits, eases overcrowding in outpatient centers, and allays worry among patients with chronic disease.</p>
    </sec>
    <sec>
      <title>Strengths, Limitations, and Future Directions</title>
      <p>Pandemics pose unique challenges to health care delivery. As our experiences from Western China illustrate, although telemedicine will not solve all challenges, it can provide rapid access to specialists who are unavailable in person. With the rapid development of the internet and smartphone apps, telemedicine has transitioned to a multimodal paradigm, offering greater possibilities and convenience. The successes of telemedicine in Western China may provide a useful reference for other parts of the world. Prerequisites for success include sufficient financial resources, technological infrastructure, and overall arrangement of policymakers.</p>
      <p>Telemedicine utilizes information and telecommunications technology to transfer medical information for diagnosis, therapy, and education. Although telemedicine clearly has a wide range of potential benefits, it also has some disadvantages. The main drawbacks of telemedicine are a breakdown in the relationship between health professionals and their patients; a breakdown in the relationship between health professionals; issues concerning the quality of health information; and organizational and bureaucratic difficulties [<xref ref-type="bibr" rid="ref5">5</xref>]. In the future, with advancements in technology (eg, the application of 5G networks to improve the effect of video transmission) and improvement in the management experience of telemedicine by policymakers, the abovementioned limitations can be minimized, and telemedicine may become a sustainable, mainstream solution for both public health emergencies and routine medicine.</p>
    </sec>
  </body>
  <back>
    <app-group/>
    <glossary>
      <title>Abbreviations</title>
      <def-list>
        <def-item>
          <term id="abb1">CFR</term>
          <def>
            <p>case fatality rate</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb2">COVID-19</term>
          <def>
            <p>coronavirus disease</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb3">CT</term>
          <def>
            <p>computed tomography</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb4">MERS</term>
          <def>
            <p>Middle East respiratory syndrome</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb6">SARS</term>
          <def>
            <p>severe acute respiratory syndrome</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb5">SARS-CoV-2</term>
          <def>
            <p>severe acute respiratory syndrome coronavirus 2</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb7">WCHSU</term>
          <def>
            <p>West China Hospital of Sichuan University</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb8">WHO</term>
          <def>
            <p>World Health Organization</p>
          </def>
        </def-item>
      </def-list>
    </glossary>
    <ack>
      <p>This work was supported by the Sichuan Science and Technology Support Program (2020YFS0002).</p>
      <p>The data reported in the article are available from the corresponding authors, upon request from qualified investigators.</p>
    </ack>
    <fn-group>
      <fn fn-type="con">
        <p>All authors were involved in drafting the manuscript and agreed to its publication. All authors read and approved their sections of the final manuscript. DZ and WL read and approved all sections of the final manuscript.</p>
      </fn>
      <fn fn-type="conflict">
        <p>None declared.</p>
      </fn>
    </fn-group>
    <ref-list>
      <ref id="ref1">
        <label>1</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Cucinotta</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Vanelli</surname>
              <given-names>M</given-names>
            </name>
          </person-group>
          <article-title>WHO Declares COVID-19 a Pandemic</article-title>
          <source>Acta Biomed</source>
          <year>2020</year>
          <month>03</month>
          <day>19</day>
          <volume>91</volume>
          <issue>1</issue>
          <fpage>157</fpage>
          <lpage>160</lpage>
          <pub-id pub-id-type="doi">10.23750/abm.v91i1.9397</pub-id>
          <pub-id pub-id-type="medline">32191675</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref2">
        <label>2</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Wu</surname>
              <given-names>Z</given-names>
            </name>
            <name name-style="western">
              <surname>McGoogan</surname>
              <given-names>JM</given-names>
            </name>
          </person-group>
          <article-title>Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention</article-title>
          <source>JAMA</source>
          <year>2020</year>
          <month>02</month>
          <day>24</day>
          <pub-id pub-id-type="doi">10.1001/jama.2020.2648</pub-id>
          <pub-id pub-id-type="medline">32091533</pub-id>
          <pub-id pub-id-type="pii">2762130</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref3">
        <label>3</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Lurie</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Carr</surname>
              <given-names>BG</given-names>
            </name>
          </person-group>
          <article-title>The Role of Telehealth in the Medical Response to Disasters</article-title>
          <source>JAMA Intern Med</source>
          <year>2018</year>
          <month>06</month>
          <day>01</day>
          <volume>178</volume>
          <issue>6</issue>
          <fpage>745</fpage>
          <lpage>746</lpage>
          <pub-id pub-id-type="doi">10.1001/jamainternmed.2018.1314</pub-id>
          <pub-id pub-id-type="medline">29710200</pub-id>
          <pub-id pub-id-type="pii">2678828</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref4">
        <label>4</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Hollander</surname>
              <given-names>JE</given-names>
            </name>
            <name name-style="western">
              <surname>Carr</surname>
              <given-names>BG</given-names>
            </name>
          </person-group>
          <article-title>Virtually Perfect? Telemedicine for Covid-19</article-title>
          <source>N Engl J Med</source>
          <year>2020</year>
          <month>04</month>
          <day>30</day>
          <volume>382</volume>
          <issue>18</issue>
          <fpage>1679</fpage>
          <lpage>1681</lpage>
          <pub-id pub-id-type="doi">10.1056/NEJMp2003539</pub-id>
          <pub-id pub-id-type="medline">32160451</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref5">
        <label>5</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Hjelm</surname>
              <given-names>NM</given-names>
            </name>
          </person-group>
          <article-title>Benefits and drawbacks of telemedicine</article-title>
          <source>J Telemed Telecare</source>
          <year>2005</year>
          <month>01</month>
          <volume>11</volume>
          <issue>2</issue>
          <fpage>60</fpage>
          <lpage>70</lpage>
          <pub-id pub-id-type="doi">10.1258/1357633053499886</pub-id>
          <pub-id pub-id-type="medline">15829049</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref6">
        <label>6</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Wang</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Li</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Zhu</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Hong</surname>
              <given-names>Z</given-names>
            </name>
            <name name-style="western">
              <surname>An</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Yang</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Ren</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Zou</surname>
              <given-names>X</given-names>
            </name>
            <name name-style="western">
              <surname>Huang</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Chi</surname>
              <given-names>X</given-names>
            </name>
            <name name-style="western">
              <surname>Chen</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Hong</surname>
              <given-names>Z</given-names>
            </name>
            <name name-style="western">
              <surname>Wang</surname>
              <given-names>W</given-names>
            </name>
            <name name-style="western">
              <surname>Xu</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>He</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Li</surname>
              <given-names>W</given-names>
            </name>
            <name name-style="western">
              <surname>Zhou</surname>
              <given-names>D</given-names>
            </name>
          </person-group>
          <article-title>Assessment of Utilization and Cost-Effectiveness of Telemedicine Program in Western Regions of China: A 12-Year Study of 249 Hospitals Across 112 Cities</article-title>
          <source>Telemed J E Health</source>
          <year>2016</year>
          <month>11</month>
          <volume>22</volume>
          <issue>11</issue>
          <fpage>909</fpage>
          <lpage>920</lpage>
          <pub-id pub-id-type="doi">10.1089/tmj.2015.0213</pub-id>
          <pub-id pub-id-type="medline">27314300</pub-id>
        </nlm-citation>
      </ref>
    </ref-list>
  </back>
</article>
