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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JMIR</journal-id>
      <journal-id journal-id-type="nlm-ta">J Med Internet Res</journal-id>
      <journal-title>Journal of Medical Internet Research</journal-title>
      <issn pub-type="epub">1438-8871</issn>
      <publisher>
        <publisher-name>JMIR Publications</publisher-name>
        <publisher-loc>Toronto, Canada</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">v22i11e22706</article-id>
      <article-id pub-id-type="pmid">33151152</article-id>
      <article-id pub-id-type="doi">10.2196/22706</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Review</subject>
        </subj-group>
        <subj-group subj-group-type="article-type">
          <subject>Review</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>A Digitally Competent Health Workforce: Scoping Review of Educational Frameworks</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="editor">
          <name>
            <surname>Eysenbach</surname>
            <given-names>Gunther</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Li</surname>
            <given-names>Sheyu</given-names>
          </name>
        </contrib>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Day</surname>
            <given-names>Karen</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib id="contrib1" contrib-type="author">
          <name name-style="western">
            <surname>Nazeha</surname>
            <given-names>Nuraini</given-names>
          </name>
          <degrees>BA</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-1935-5499</ext-link>
        </contrib>
        <contrib id="contrib2" contrib-type="author">
          <name name-style="western">
            <surname>Pavagadhi</surname>
            <given-names>Deepali</given-names>
          </name>
          <degrees>MSc</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0003-4337-8137</ext-link>
        </contrib>
        <contrib id="contrib3" contrib-type="author">
          <name name-style="western">
            <surname>Kyaw</surname>
            <given-names>Bhone Myint</given-names>
          </name>
          <degrees>MBBS, MSc, PhD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-1750-0330</ext-link>
        </contrib>
        <contrib id="contrib4" contrib-type="author" corresp="yes">
          <name name-style="western">
            <surname>Car</surname>
            <given-names>Josip</given-names>
          </name>
          <degrees>MD, PhD, FRCPE, FFPH</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <address>
            <institution>Centre for Population Health Sciences</institution>
            <institution>Lee Kong Chian School of Medicine</institution>
            <institution>Nanyang Technological University</institution>
            <addr-line>11 Mandalay Road</addr-line>
            <addr-line>Singapore</addr-line>
            <country>Singapore</country>
            <phone>65 69047005</phone>
            <email>josip.car@ntu.edu.sg</email>
          </address>
          <xref rid="aff2" ref-type="aff">2</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0001-8969-371X</ext-link>
        </contrib>
        <contrib id="contrib5" contrib-type="author">
          <name name-style="western">
            <surname>Jimenez</surname>
            <given-names>Geronimo</given-names>
          </name>
          <degrees>MA</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <xref rid="aff3" ref-type="aff">3</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-1304-426X</ext-link>
        </contrib>
        <contrib id="contrib6" contrib-type="author">
          <name name-style="western">
            <surname>Tudor Car</surname>
            <given-names>Lorainne</given-names>
          </name>
          <degrees>MD, MSc, PhD</degrees>
          <xref rid="aff2" ref-type="aff">2</xref>
          <xref rid="aff4" ref-type="aff">4</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0001-8414-7664</ext-link>
        </contrib>
      </contrib-group>
      <aff id="aff1">
        <label>1</label>
        <institution>Centre for Population Health Sciences</institution>
        <institution>Lee Kong Chian School of Medicine</institution>
        <institution>Nanyang Technological University</institution>
        <addr-line>Singapore</addr-line>
        <country>Singapore</country>
      </aff>
      <aff id="aff2">
        <label>2</label>
        <institution>Department of Primary Care and Public Health</institution>
        <institution>School of Public Health</institution>
        <institution>Imperial College London</institution>
        <addr-line>London</addr-line>
        <country>United Kingdom</country>
      </aff>
      <aff id="aff3">
        <label>3</label>
        <institution>Department of Public Health and Primary Care</institution>
        <institution>Leiden University Medical Center</institution>
        <addr-line>Netherlands</addr-line>
        <country>Netherlands</country>
      </aff>
      <aff id="aff4">
        <label>4</label>
        <institution>Family Medicine and Primary Care</institution>
        <institution>Lee Kong Chian School of Medicine</institution>
        <institution>Nanyang Technological University</institution>
        <addr-line>Singapore</addr-line>
        <country>Singapore</country>
      </aff>
      <author-notes>
        <corresp>Corresponding Author: Josip Car <email>josip.car@ntu.edu.sg</email></corresp>
      </author-notes>
      <pub-date pub-type="collection">
        <month>11</month>
        <year>2020</year>
      </pub-date>
      <pub-date pub-type="epub">
        <day>5</day>
        <month>11</month>
        <year>2020</year>
      </pub-date>
      <volume>22</volume>
      <issue>11</issue>
      <elocation-id>e22706</elocation-id>
      <history>
        <date date-type="received">
          <day>22</day>
          <month>7</month>
          <year>2020</year>
        </date>
        <date date-type="rev-request">
          <day>1</day>
          <month>9</month>
          <year>2020</year>
        </date>
        <date date-type="rev-recd">
          <day>15</day>
          <month>9</month>
          <year>2020</year>
        </date>
        <date date-type="accepted">
          <day>15</day>
          <month>9</month>
          <year>2020</year>
        </date>
      </history>
      <copyright-statement>©Nuraini Nazeha, Deepali Pavagadhi, Bhone Myint Kyaw, Josip Car, Geronimo Jimenez, Lorainne Tudor Car. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 05.11.2020.</copyright-statement>
      <copyright-year>2020</copyright-year>
      <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
        <p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Journal of Medical Internet Research, is properly cited. The complete bibliographic information, a link to the original publication on http://www.jmir.org/, as well as this copyright and license information must be included.</p>
      </license>
      <self-uri xlink:href="https://www.jmir.org/2020/11/e22706" xlink:type="simple"/>
      <abstract>
        <sec sec-type="background">
          <title>Background</title>
          <p>Digital health technologies can be key to improving health outcomes, provided health care workers are adequately trained to use these technologies. There have been efforts to identify digital competencies for different health care worker groups; however, an overview of these efforts has yet to be consolidated and analyzed.</p>
        </sec>
        <sec sec-type="objective">
          <title>Objective</title>
          <p>The review aims to identify and study existing digital health competency frameworks for health care workers and provide recommendations for future digital health training initiatives and framework development.</p>
        </sec>
        <sec sec-type="methods">
          <title>Methods</title>
          <p>A literature search was performed to collate digital health competency frameworks published from 2000. A total of 6 databases including gray literature sources such as OpenGrey, ResearchGate, Google Scholar, Google, and websites of relevant associations were searched in November 2019. Screening and data extraction were performed in parallel by the reviewers. The included evidence is narratively described in terms of characteristics, evolution, and structural composition of frameworks. A thematic analysis was also performed to identify common themes across the included frameworks.</p>
        </sec>
        <sec sec-type="results">
          <title>Results</title>
          <p>In total, 30 frameworks were included in this review, a majority of which aimed at nurses, originated from high-income countries, were published since 2016, and were developed via literature reviews, followed by expert consultations. The thematic analysis uncovered 28 digital health competency domains across the included frameworks. The most prevalent domains pertained to basic information technology literacy, health information management, digital communication, ethical, legal, or regulatory requirements, and data privacy and security. The Health Information Technology Competencies framework was found to be the most comprehensive framework, as it presented 21 out of the 28 identified domains, had the highest number of competencies, and targeted a wide variety of health care workers.</p>
        </sec>
        <sec sec-type="conclusions">
          <title>Conclusions</title>
          <p>Digital health training initiatives should focus on competencies relevant to a particular health care worker group, role, level of seniority, and setting. The findings from this review can inform and guide digital health training initiatives. The most prevalent competency domains identified represent essential interprofessional competencies to be incorporated into health care workers’ training. Digital health frameworks should be regularly updated with novel digital health technologies, be applicable to low- and middle-income countries, and include overlooked health care worker groups such as allied health professionals.</p>
        </sec>
      </abstract>
      <kwd-group>
        <kwd>digital health</kwd>
        <kwd>eHealth</kwd>
        <kwd>health professions education</kwd>
        <kwd>digital competency</kwd>
        <kwd>competency</kwd>
        <kwd>framework</kwd>
        <kwd>review</kwd>
        <kwd>medical education</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec sec-type="introduction">
      <title>Introduction</title>
      <sec>
        <title>Background</title>
        <p>Over the last three decades, there has been considerable interest in the use of digital health to enhance the quality, efficiency, and safety of health care [<xref ref-type="bibr" rid="ref1">1</xref>,<xref ref-type="bibr" rid="ref2">2</xref>]. Digital health and eHealth are often used interchangeably and broadly defined as “the use of information and communications technology in support of health and health-related fields” [<xref ref-type="bibr" rid="ref3">3</xref>]. An analysis of various digital health definitions revealed three distinct yet overlapping uses such as monitoring, tracking, and informing health (eg, mobile devices, mobile sensors and wearables, apps, social media); enabling health communication among various stakeholders (eg, telehealth, virtual consultations); and storing, managing, and utilizing health data (eg, electronic medical records, electronic medication systems) [<xref ref-type="bibr" rid="ref4">4</xref>]. Digital health tools have the potential to provide health care workers with a holistic view of patients’ medical conditions through access to their health-related data and improved communication, regardless of distance and access [<xref ref-type="bibr" rid="ref5">5</xref>]. Furthermore, the use of digital technology in health care could potentially reduce turnaround times, resource use, medication errors, and adverse drug events; increase the use of preventive care; and enable greater adherence to clinical guidelines [<xref ref-type="bibr" rid="ref6">6</xref>-<xref ref-type="bibr" rid="ref8">8</xref>].</p>
        <p>Training and educating health care workers to be digitally competent is important for several reasons.</p>
        <p>First, with the growing use of digital technology in health care, the roles and responsibilities of the health workforce are transforming in an unprecedented manner, intensifying the need for capacity building and continuous professional development. For example, a recent review commissioned by the United Kingdom Secretary of State for Health and Social Care (ie, the Topol Review) reported that within the next two decades, the majority of jobs in the National Health Service (NHS) will have a digital component [<xref ref-type="bibr" rid="ref9">9</xref>]. Second, the importance and potential of remote care has been brought to light recently with the COVID-19 pandemic. Virtual consultation devices and electronic systems are indispensable tools used to diagnose and treat patients with potential COVID-19 infections as well as all other infections [<xref ref-type="bibr" rid="ref10">10</xref>,<xref ref-type="bibr" rid="ref11">11</xref>]. Third, even though the current and next generation of practitioners may be seen as “digital natives” [<xref ref-type="bibr" rid="ref12">12</xref>], surveys of health care workers show that they would appreciate more training on digital technology [<xref ref-type="bibr" rid="ref13">13</xref>,<xref ref-type="bibr" rid="ref14">14</xref>]. Finally, improving digital literacy capabilities could lead to better adoption and implementation of digital services and technologies in health care settings [<xref ref-type="bibr" rid="ref15">15</xref>]. Similarly, poor digital health literacy was found to be the most common barrier to the digital transformation of health care [<xref ref-type="bibr" rid="ref16">16</xref>], and thus, the adoption of health technologies has been gradual in countries such as the United States [<xref ref-type="bibr" rid="ref17">17</xref>], Europe [<xref ref-type="bibr" rid="ref16">16</xref>], and Australia [<xref ref-type="bibr" rid="ref18">18</xref>]. For the above-mentioned reasons, there is an increasing number of medical schools introducing digital health training into their curricula [<xref ref-type="bibr" rid="ref12">12</xref>,<xref ref-type="bibr" rid="ref19">19</xref>,<xref ref-type="bibr" rid="ref20">20</xref>].</p>
        <p>Such training programs should be guided by a clear framework of digital health competencies suited for different health care worker groups, settings, contexts, seniority, and role. Although there is an increasing number of individual digital health competency frameworks and reviews focusing on a specific health care worker role or setting [<xref ref-type="bibr" rid="ref21">21</xref>-<xref ref-type="bibr" rid="ref24">24</xref>], there is a need for consolidation, analysis, and a comprehensive overview of existing frameworks for all health care worker groups. This includes frameworks that are specific for and those that are relevant across different health professions, roles, or settings. Such an overview is important to inform increasingly interdisciplinary teams working in medicine and health care and corresponding future training initiatives, policy development, and research.</p>
      </sec>
      <sec>
        <title>Objectives</title>
        <p>The objective of this review is to identify and analyze the available digital health competency frameworks, regardless of health profession, role, or setting. This scoping review takes into consideration the heterogeneity and complexity of this field, and we aim to identify (1) the intended applications of digital health competency frameworks; (2) the methodologies employed; (3) the targeted audience in terms of health professions and settings; and (4) the type of competencies included in the frameworks. By doing so, we aim to provide an in-depth analysis of the existing frameworks as well as identify potential gaps and propose recommendations for the development of future frameworks and digital health training initiatives.</p>
      </sec>
    </sec>
    <sec sec-type="methods">
      <title>Methods</title>
      <sec>
        <title>Study Design</title>
        <p>We followed the guidelines by the Joanna Briggs Institute [<xref ref-type="bibr" rid="ref25">25</xref>] in performing a literature review and guidelines by Tricco et al [<xref ref-type="bibr" rid="ref26">26</xref>] in creating a Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) flow chart. The protocol for this review was registered with the Open Science Framework [<xref ref-type="bibr" rid="ref27">27</xref>]. In this review, we used the World Health Organization’s definition of digital health as “the combination of e-health and m-health as well as emerging areas, such as the use of advanced computing sciences in big data, genomics and artificial intelligence” [<xref ref-type="bibr" rid="ref3">3</xref>].</p>
      </sec>
      <sec>
        <title>Eligibility Criteria</title>
        <p>We included studies and reports focusing on the development and reporting of a digital health competency framework for health care workers. In this review, a competency framework is defined as a repository or a model that identifies, enlists, structures, and organizes competencies into meaningful categories and that has been developed via a systematic methodology or a relevant, established organization. This definition was developed <italic>a priori</italic> by referring to the existing definitions and descriptions, and looking at the common features of formerly identified digital health competency frameworks applicable to health care workers [<xref ref-type="bibr" rid="ref28">28</xref>]. We included studies and reports on all health professions, including pre- and in-service, health care settings, and languages. Studies before January 2000 were excluded because digital health has evolved at a rapid pace, with substantial changes over the last two decades. The details of the inclusion and exclusion criteria are listed in <xref ref-type="supplementary-material" rid="app1">Multimedia Appendix 1</xref>.</p>
      </sec>
      <sec>
        <title>Search Strategy</title>
        <p>The search strategy was developed collaboratively and iteratively by the reviewers with support from an experienced medical librarian and was guided by the following: (1) the sensitivity of the search strategy to relevant articles identified from previous manual searches and (2) the total number of relevant results in the first few pages of results in Medical Literature Analysis and Retrieval System Online (MEDLINE) and EMBASE (Excerpta Medica dataBASE). The final MEDLINE search strategy (<xref ref-type="supplementary-material" rid="app2">Multimedia Appendix 2</xref>) was translated to other databases. Subsequently, the following 6 databases were searched on November 8, 2019: MEDLINE, EMBASE, Cumulative Index to Nursing and Allied Health Literature (CINAHL), Education Resources Information Center (ERIC), PsycINFO, and the Cochrane Library. MEDLINE, EMBASE, ERIC, and PsycINFO were accessed via the Ovid platform, and CINAHL was accessed via EBSCOhost. We expected that there would be substantial unpublished work in this area, for which searches were performed using pertinent keywords (<xref ref-type="supplementary-material" rid="app3">Multimedia Appendix 3</xref>) in OpenGrey, ResearchGate, and the first 10 pages of Google and Google Scholar. Websites of relevant professional associations (eg, International Medical Informatics Association [IMIA]), accreditation councils (eg, the US Accreditation Council for Graduate Medical Education [ACGME]), and key government websites (eg, Digital Health Canada, NHS Digital) were also searched (<xref ref-type="supplementary-material" rid="app4">Multimedia Appendix 4</xref>).</p>
      </sec>
      <sec>
        <title>Screening and Data Extraction</title>
        <p>The reviewers screened the search results and assessed the full-text studies for inclusion. For the title and abstract screening, Covidence tool [<xref ref-type="bibr" rid="ref29">29</xref>], a web-based software platform, and, for full-text screening, EndNote X8 were used. Subsequently, a data extraction form was used to record information from the selected full-text studies using Microsoft Excel. The form was developed to be in line with the research objectives and was piloted by reviewers on 3 studies. The form was further amended (<xref ref-type="supplementary-material" rid="app5">Multimedia Appendix 5</xref>), and relevant data were extracted by reviewers. Each round of screening and data extraction process was performed by a pair of reviewers independently, and results were compared thereafter. Disagreements between reviewers were resolved by discussion, and where required, a third reviewer was engaged as an arbiter.</p>
      </sec>
      <sec>
        <title>Data Synthesis</title>
        <p>We analyzed the identified digital health competency frameworks in terms of their coverage of health professions, education level (eg, preservice or in-service), geographical applicability (ie, local or organizational, regional, national, international), health care settings (eg, acute care, emergency care, primary care), and other comparable features such as source and methodology. In frameworks that did not specify their methodology, an additional internet search was performed to retrieve information on the methods employed for framework development. Following this, we narratively synthesized and described framework characteristics, the evolution of frameworks over time, and the structural composition of competencies.</p>
        <p>In addition, we performed a thematic analysis according to a list of steps proposed by Nowell et al [<xref ref-type="bibr" rid="ref30">30</xref>] to understand the types of digital health competency categories presented in the frameworks. From the included frameworks, 2 reviewers independently classified competency categories into overarching domains. Studies that did not publish the full version of the framework were excluded from the thematic analysis, together with competency categories that were aimed at non–health care workers in a health care setting or irrelevant to digital competencies. Frameworks with ambiguous categories were excluded unless pertaining category descriptions or competencies were provided. Frameworks with competency themes or statements, with no distinct categories, were also included in the analysis by carefully allocating them to the identified domains. In some cases, where a single competency statement or theme encompassed several components of a competency, it was allocated to more than one relevant domain. After discussion and consensus, the reviewers derived a consolidated list of identified domains and their definitions and the prevalence of each identified domain across the included frameworks.</p>
      </sec>
    </sec>
    <sec sec-type="results">
      <title>Results</title>
      <sec>
        <title>Study Characteristics</title>
        <p>The search generated 14,229 articles, of which 14,091 were from database searches and 138 from gray literature. After duplicates were removed and screening was completed, 33 articles were deemed eligible for inclusion. Of these, 27 articles presented individual frameworks. The remaining 6 articles presented preliminary findings followed by finalized versions of their frameworks (Staggers et al [<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref32">32</xref>]; Egbert et al [<xref ref-type="bibr" rid="ref33">33</xref>,<xref ref-type="bibr" rid="ref34">34</xref>]; Hubner et al [<xref ref-type="bibr" rid="ref35">35</xref>,<xref ref-type="bibr" rid="ref36">36</xref>]), adding 3 more individual frameworks. As a result, a total of 30 frameworks are presented in this review (<xref rid="figure1" ref-type="fig">Figure 1</xref>), of which 16 were found through a gray literature search.</p>
        <fig id="figure1" position="float">
          <label>Figure 1</label>
          <caption>
            <p>PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) flow chart.</p>
          </caption>
          <graphic xlink:href="jmir_v22i11e22706_fig1.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
        </fig>
        <p>In terms of methodology, 14 frameworks employed literature review as an initial step, subsequently finalizing the frameworks through the use of expert consultations (n=5) [<xref ref-type="bibr" rid="ref37">37</xref>-<xref ref-type="bibr" rid="ref41">41</xref>], focus group discussions (n=3) [<xref ref-type="bibr" rid="ref33">33</xref>,<xref ref-type="bibr" rid="ref34">34</xref>,<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref43">43</xref>], Delphi methodology (n=5) [<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref32">32</xref>,<xref ref-type="bibr" rid="ref44">44</xref>-<xref ref-type="bibr" rid="ref47">47</xref>], or expert surveys [<xref ref-type="bibr" rid="ref48">48</xref>]. In total, 11 other frameworks used one or a combination of methodologies (ie, Delphi, expert discussions, workshops, surveys) to reach consensus, largely by engaging various experts such as informaticists, health professionals, educators, and academics [<xref ref-type="bibr" rid="ref21">21</xref>,<xref ref-type="bibr" rid="ref22">22</xref>,<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref49">49</xref>-<xref ref-type="bibr" rid="ref56">56</xref>]. Of the remaining frameworks, 2 used only literature review to select relevant competencies [<xref ref-type="bibr" rid="ref57">57</xref>,<xref ref-type="bibr" rid="ref58">58</xref>], and 3 frameworks were built on the foundation of other published frameworks [<xref ref-type="bibr" rid="ref59">59</xref>-<xref ref-type="bibr" rid="ref61">61</xref>]. In addition, the frameworks were developed by a team of authors from a single university or institute (eg, University of Minnesota, School of Nursing) [<xref ref-type="bibr" rid="ref44">44</xref>], by an international- or national-level organization (eg, IMIA, Australian Health Informatics Council [AHIEC]) [<xref ref-type="bibr" rid="ref49">49</xref>,<xref ref-type="bibr" rid="ref57">57</xref>], or by means of a collaborative effort to produce frameworks such as Technology Informatics Guiding Education Reform (TIGER) [<xref ref-type="bibr" rid="ref35">35</xref>,<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref52">52</xref>] and Health Information Technology Competencies (HITCOMP) [<xref ref-type="bibr" rid="ref41">41</xref>].</p>
        <p>In terms of geographical relevance, 15 frameworks were country-specific [<xref ref-type="bibr" rid="ref21">21</xref>,<xref ref-type="bibr" rid="ref33">33</xref>,<xref ref-type="bibr" rid="ref37">37</xref>,<xref ref-type="bibr" rid="ref38">38</xref>,<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref45">45</xref>,<xref ref-type="bibr" rid="ref47">47</xref>,<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref50">50</xref>,<xref ref-type="bibr" rid="ref55">55</xref>-<xref ref-type="bibr" rid="ref59">59</xref>], 1 was specific to the European Union region [<xref ref-type="bibr" rid="ref61">61</xref>], 5 were applicable globally [<xref ref-type="bibr" rid="ref35">35</xref>,<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref41">41</xref>,<xref ref-type="bibr" rid="ref49">49</xref>,<xref ref-type="bibr" rid="ref52">52</xref>,<xref ref-type="bibr" rid="ref54">54</xref>], and the remaining did not specify (n=9). In terms of health care settings, 4 were developed for remote care delivery [<xref ref-type="bibr" rid="ref39">39</xref>,<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref53">53</xref>,<xref ref-type="bibr" rid="ref60">60</xref>], 1 framework each for hospitals [<xref ref-type="bibr" rid="ref48">48</xref>], acute care [<xref ref-type="bibr" rid="ref41">41</xref>], and homecare [<xref ref-type="bibr" rid="ref50">50</xref>], while the remaining frameworks either were applicable to all health care settings (n=5) [<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref45">45</xref>,<xref ref-type="bibr" rid="ref56">56</xref>,<xref ref-type="bibr" rid="ref57">57</xref>,<xref ref-type="bibr" rid="ref59">59</xref>] or did not specify (n=18). In terms of health professions, 14 frameworks targeted nurses, 4 targeted doctors, of which one also included dentists, and 1 framework each targeted psychiatrists, dietitians, and public health professionals; 9 frameworks targeted health care workers in general, of which 5 specified the inclusion of administrative, information technology (IT) support, and health informatics specialist roles [<xref ref-type="bibr" rid="ref41">41</xref>,<xref ref-type="bibr" rid="ref52">52</xref>,<xref ref-type="bibr" rid="ref54">54</xref>,<xref ref-type="bibr" rid="ref57">57</xref>,<xref ref-type="bibr" rid="ref61">61</xref>], and 1 specified the inclusion of allied health professionals [<xref ref-type="bibr" rid="ref39">39</xref>]. Among the nursing frameworks, 7 were meant for in-service nurses [<xref ref-type="bibr" rid="ref21">21</xref>,<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref32">32</xref>,<xref ref-type="bibr" rid="ref42">42</xref>-<xref ref-type="bibr" rid="ref44">44</xref>,<xref ref-type="bibr" rid="ref46">46</xref>,<xref ref-type="bibr" rid="ref48">48</xref>], 5 for preservice nursing students [<xref ref-type="bibr" rid="ref33">33</xref>-<xref ref-type="bibr" rid="ref37">37</xref>,<xref ref-type="bibr" rid="ref53">53</xref>,<xref ref-type="bibr" rid="ref58">58</xref>], and 2 for both [<xref ref-type="bibr" rid="ref22">22</xref>,<xref ref-type="bibr" rid="ref50">50</xref>]. Of the 4 medicine-focused frameworks, one focused on in-service doctors [<xref ref-type="bibr" rid="ref40">40</xref>], another on preservice medical students [<xref ref-type="bibr" rid="ref55">55</xref>], and 2 on both [<xref ref-type="bibr" rid="ref59">59</xref>,<xref ref-type="bibr" rid="ref60">60</xref>]. The framework characteristics and summary of the findings of the included studies are presented in <xref ref-type="table" rid="table1">Table 1</xref> and <xref ref-type="table" rid="table2">Table 2</xref>, respectively. Additional details of the included studies are presented in <xref ref-type="supplementary-material" rid="app6">Multimedia Appendix 6</xref> [<xref ref-type="bibr" rid="ref21">21</xref>,<xref ref-type="bibr" rid="ref22">22</xref>,<xref ref-type="bibr" rid="ref31">31</xref>-<xref ref-type="bibr" rid="ref63">63</xref>].</p>
        <table-wrap position="float" id="table1">
          <label>Table 1</label>
          <caption>
            <p>Characteristics of the 30 frameworks.</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="30"/>
            <col width="770"/>
            <col width="200"/>
            <thead>
              <tr valign="top">
                <td colspan="2">Characteristics</td>
                <td>Values, n (%)</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td colspan="3">
                  <bold>Publication dates</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>2000-2010</td>
                <td>6 (20)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>2010-2019</td>
                <td>24 (80)</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Source</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Database</td>
                <td>14 (47)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Gray literature</td>
                <td>16 (53)</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Geographical setting</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Country</td>
                <td>15 (50)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Region</td>
                <td>1 (3)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>International</td>
                <td>5 (17)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Not specified</td>
                <td>9 (30)</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Health care setting</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Acute care</td>
                <td>1 (3)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Home care</td>
                <td>1 (3)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Hospitals</td>
                <td>1 (3)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Remote care</td>
                <td>4 (13)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>All health care settings</td>
                <td>5 (17)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Not specified</td>
                <td>18 (60)</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Health care profession</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Nursing</td>
                <td>14 (47)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Medicine</td>
                <td>4 (13)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Allied health</td>
                <td>1 (3)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Psychiatry</td>
                <td>1 (3)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Public health professionals</td>
                <td>1 (3)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Unspecified or applicable to multiple health professions</td>
                <td>9 (30)</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Educational level</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>In-service</td>
                <td>13 (43)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Preservice</td>
                <td>9 (30)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Both</td>
                <td>8 (27)</td>
              </tr>
            </tbody>
          </table>
        </table-wrap>
        <table-wrap position="float" id="table2">
          <label>Table 2</label>
          <caption>
            <p>Summary of findings of included studies.</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="180"/>
            <col width="180"/>
            <col width="200"/>
            <col width="220"/>
            <col width="220"/>
            <thead>
              <tr valign="top">
                <td>Study ID</td>
                <td>Context (country; health care setting)</td>
                <td>Intended audience (profession; educational level)</td>
                <td>Methodology</td>
                <td>Organization of framework</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td>Academy of Medical Royal Colleges (2011) [<xref ref-type="bibr" rid="ref59">59</xref>]</td>
                <td>Scotland; all</td>
                <td>Doctors and dentists; preservice and in-service</td>
                <td>Framework aligned with other competency frameworks</td>
                <td>418 competencies divided into 20 domains, and further subdivided into outcomes (ie, knowledge, skills, behavior)</td>
              </tr>
              <tr valign="top">
                <td>AHIEC<sup>a</sup> (2011) [<xref ref-type="bibr" rid="ref57">57</xref>]</td>
                <td>Australia; all</td>
                <td>All HCPs<sup>b</sup> including admin and IT<sup>c</sup> support staff; preservice and in- service</td>
                <td>Literature review drew on a wide range of major initiatives</td>
                <td>45 competencies grouped into 3 categories and assigned a competency level ranging from 1 to 6</td>
              </tr>
              <tr valign="top">
                <td>AFMC<sup>d</sup> in Partnership with Canada Health Infoway (2014) [<xref ref-type="bibr" rid="ref55">55</xref>]</td>
                <td>Canada; not specified</td>
                <td>Medical students; preservice</td>
                <td>Framework was based on contributions from experts</td>
                <td>25 competencies classified according to physicians’ roles and each competency is further divided into preclinical and clerkship milestones</td>
              </tr>
              <tr valign="top">
                <td>Australian Nursing and Midwifery Federation (2015) [<xref ref-type="bibr" rid="ref42">42</xref>]</td>
                <td>Australia; all</td>
                <td>Nurses and midwives (registered nurses, midwives, and enrolled nurses); in-service</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Literature review</p>
                    </list-item>
                    <list-item>
                      <p>Consensus via focus groups, on-line survey, and expert interviews</p>
                    </list-item>
                  </list>
                </td>
                <td>53 competencies grouped into 3 categories and 10 subcategories</td>
              </tr>
              <tr valign="top">
                <td>Ayres (2012) [<xref ref-type="bibr" rid="ref45">45</xref>]</td>
                <td>United States; all</td>
                <td>Registered dietitians, and dietetic technicians, registered and students; preservice and in-service</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Literature review</p>
                    </list-item>
                    <list-item>
                      <p>Delphi study</p>
                    </list-item>
                  </list>
                </td>
                <td>216 competencies grouped into 3 categories for each level of practice</td>
              </tr>
              <tr valign="top">
                <td>Barakat (2013) [<xref ref-type="bibr" rid="ref50">50</xref>]</td>
                <td>The Netherlands; home care</td>
                <td>Nurses; pre-service and in-service</td>
                <td>A two-day collaborative workshop with academic experts</td>
                <td>14 competencies organized into 5 themes</td>
              </tr>
              <tr valign="top">
                <td>Brunner (2018) [<xref ref-type="bibr" rid="ref47">47</xref>]</td>
                <td>Australia; not specified</td>
                <td>Health graduates; preservice</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Literature review</p>
                    </list-item>
                    <list-item>
                      <p>Focus group discussion</p>
                    </list-item>
                    <list-item>
                      <p>Delphi study</p>
                    </list-item>
                  </list>
                </td>
                <td>40 competencies organized into 4 domains and further divided into knowledge and performance cues</td>
              </tr>
              <tr valign="top">
                <td>Chang (2011) [<xref ref-type="bibr" rid="ref21">21</xref>]</td>
                <td>Taiwan; not specified</td>
                <td>Nurses; in-service</td>
                <td>3 web-based Delphi rounds conducted with experts</td>
                <td>318 competencies grouped into 3 categories for each level of practice</td>
              </tr>
              <tr valign="top">
                <td>Collins (2017) [<xref ref-type="bibr" rid="ref46">46</xref>]</td>
                <td>Not specified</td>
                <td>Nurse leaders; in-service</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Literature review</p>
                    </list-item>
                    <list-item>
                      <p>Delphi study (3 rounds)</p>
                    </list-item>
                    <list-item>
                      <p>Exploratory factor analysis for scale optimization and factor identification</p>
                    </list-item>
                  </list>
                </td>
                <td>74 competencies organized into 15 categories, and 15 of the most relevant competencies are ranked.</td>
              </tr>
              <tr valign="top">
                <td>Crawford (2016) [<xref ref-type="bibr" rid="ref51">51</xref>]</td>
                <td>Not specified; remote care</td>
                <td>Psychiatry residents; in-service</td>
                <td>Expert panel and interviews with faculty and psychiatry residences</td>
                <td>15 competencies sorted by professional roles, with examples</td>
              </tr>
              <tr valign="top">
                <td>Curran (2003) [<xref ref-type="bibr" rid="ref22">22</xref>]</td>
                <td>Not specified</td>
                <td>Nurse practitioners; preservice and in-service</td>
                <td>Consensus with a team of nurse informaticists and nurse practitioner program directors</td>
                <td>32 competencies grouped into 3 categories</td>
              </tr>
              <tr valign="top">
                <td>Egbert (2016) [<xref ref-type="bibr" rid="ref33">33</xref>]; Egbert (2019) [<xref ref-type="bibr" rid="ref34">34</xref>]</td>
                <td>Austria, Switzerland, Germany; not specified</td>
                <td>Nurses; preservice</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Literature review</p>
                    </list-item>
                    <list-item>
                      <p>Expert survey</p>
                    </list-item>
                    <list-item>
                      <p>Focus group discussion and consensus</p>
                    </list-item>
                  </list>
                </td>
                <td>24 competency areas identified, and 5 of the most relevant areas ranked for 5 nursing roles</td>
              </tr>
              <tr valign="top">
                <td>HITCOMP<sup>e</sup> (2019) [<xref ref-type="bibr" rid="ref41">41</xref>]</td>
                <td>International; acute care</td>
                <td>All HCPs; preservice and in-service</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Literature review</p>
                    </list-item>
                    <list-item>
                      <p>Survey sent to international experts</p>
                    </list-item>
                    <list-item>
                      <p>Gap analysis</p>
                    </list-item>
                    <list-item>
                      <p>Expert consultation</p>
                    </list-item>
                  </list>
                </td>
                <td>1025 competencies organized into 33 competency areas, for 5 levels of practice across 5 domains</td>
              </tr>
              <tr valign="top">
                <td>Hilty (2015) [<xref ref-type="bibr" rid="ref60">60</xref>]</td>
                <td>Not specified; remote care</td>
                <td>Doctors, medical students; preservice and in-service</td>
                <td>Competencies organized using the US ACGME framework, with input from the CanMEDS framework</td>
                <td>Competencies listed for 8 main categories and subcategories, for each level of practice</td>
              </tr>
              <tr valign="top">
                <td>Honey (2018) [<xref ref-type="bibr" rid="ref58">58</xref>]</td>
                <td>New Zealand; not specified</td>
                <td>Registered nurses; preservice</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Curriculum mapping</p>
                    </list-item>
                    <list-item>
                      <p>Literature review</p>
                    </list-item>
                  </list>
                </td>
                <td>4 domains identified, and relevant subcategories and examples presented for each domain</td>
              </tr>
              <tr valign="top">
                <td>Hubner (2016) [<xref ref-type="bibr" rid="ref35">35</xref>]</td>
                <td>International; not specified</td>
                <td>Nurses; preservice</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Survey sent to international experts</p>
                    </list-item>
                    <list-item>
                      <p>A workshop was held to validate competencies</p>
                    </list-item>
                  </list>
                </td>
                <td>24 competency areas identified, and 6 of the most relevant areas ranked for 5 nursing roles</td>
              </tr>
              <tr valign="top">
                <td>Hubner (2018) [<xref ref-type="bibr" rid="ref36">36</xref>]</td>
                <td>International; not specified</td>
                <td>Nurses; preservice</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Survey sent to international experts</p>
                    </list-item>
                  </list>
                  <list list-type="bullet">
                    <list-item>
                      <p>A workshop was held to validate competencies</p>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>24 competency areas identified, and sorted into 6 overarching domains</p>
                    </list-item>
                    <list-item>
                      <p>10 of the most relevant areas ranked for 5 nursing roles</p>
                    </list-item>
                  </list>
                </td>
              </tr>
              <tr valign="top">
                <td>Hubner (2019) [<xref ref-type="bibr" rid="ref52">52</xref>]</td>
                <td>International; not specified</td>
                <td>All HCPs; preservice</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Adapted Hubner (2016 and 2018)’s work [<xref ref-type="bibr" rid="ref35">35</xref>,<xref ref-type="bibr" rid="ref36">36</xref>] to include more HCP roles</p>
                    </list-item>
                  </list>
                  <list list-type="bullet">
                    <list-item>
                      <p>Survey was sent to international experts</p>
                    </list-item>
                  </list>
                </td>
                <td>33 competency areas are identified, and the 10 most relevant competencies are ranked for each HCP role</td>
              </tr>
              <tr valign="top">
                <td>Hwang (2008) [<xref ref-type="bibr" rid="ref48">48</xref>]</td>
                <td>Taiwan; hospital</td>
                <td>Clinical nurses; in-service</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Literature review</p>
                    </list-item>
                    <list-item>
                      <p>Expert survey</p>
                    </list-item>
                  </list>
                </td>
                <td>49 competencies grouped into 3 main categories and subcategories</td>
              </tr>
              <tr valign="top">
                <td>Jidkov (2019) [<xref ref-type="bibr" rid="ref40">40</xref>]</td>
                <td>United Kingdom; not specified</td>
                <td>Doctors; in-service</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Literature review</p>
                    </list-item>
                    <list-item>
                      <p>Curricular content analysis</p>
                    </list-item>
                    <list-item>
                      <p>Expert consultation</p>
                    </list-item>
                  </list>
                </td>
                <td>20 competencies organized into 6 domains</td>
              </tr>
              <tr valign="top">
                <td>Maheu (2018) [<xref ref-type="bibr" rid="ref39">39</xref>]</td>
                <td>Not specified; remote care</td>
                <td>All HCPs including allied health professionals; Preservice and in-service</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Literature review</p>
                    </list-item>
                    <list-item>
                      <p>Expert consultation</p>
                    </list-item>
                  </list>
                </td>
                <td>7 domains identified, which are further broken down into 51 telebehavioral objectives, followed by 149 telebehavioral practices across 3 levels</td>
              </tr>
              <tr valign="top">
                <td>Mantas (2010) [<xref ref-type="bibr" rid="ref49">49</xref>]</td>
                <td>International; not specified</td>
                <td>All HCPs; in-service</td>
                <td>Recommendations were discussed and refined by the IMIA<sup>f</sup> task force.</td>
                <td>34 competencies organized into 3 BMHI<sup>g</sup> domains and each competency is determined if it is required by an IT user or a BMHI specialist according to 3 proficiency levels</td>
              </tr>
              <tr valign="top">
                <td>Nagle (2014) [<xref ref-type="bibr" rid="ref37">37</xref>]</td>
                <td>Canada; not specified</td>
                <td>Registered nurses; preservice</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Literature review</p>
                    </list-item>
                    <list-item>
                      <p>Consensus with experts through 3 rounds of feedback</p>
                    </list-item>
                  </list>
                </td>
                <td>19 competencies grouped into 3 domains.</td>
              </tr>
              <tr valign="top">
                <td>NHS (2018) [<xref ref-type="bibr" rid="ref56">56</xref>]</td>
                <td>United Kingdom; all</td>
                <td>All HCPs; in-service</td>
                <td>Consultations with different stakeholders and workforce groups [<xref ref-type="bibr" rid="ref62">62</xref>]</td>
                <td>An overarching domain broken down into 5 domains, each with a set of description and competencies sorted according to 4 proficiency levels</td>
              </tr>
              <tr valign="top">
                <td>Public Health Informatics Institute (2016) [<xref ref-type="bibr" rid="ref38">38</xref>]</td>
                <td>United States; not specified</td>
                <td>Public health professionals; in-service</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Literature review</p>
                    </list-item>
                    <list-item>
                      <p>Expert consultation</p>
                    </list-item>
                  </list>
                </td>
                <td>8 categories identified, each with a set of competency statement and competencies</td>
              </tr>
              <tr valign="top">
                <td>JASEHN (2018) [<xref ref-type="bibr" rid="ref61">61</xref>]</td>
                <td>Region; not specified</td>
                <td>All HCPs including admin and IT support staff; in-service</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Literature review</p>
                    </list-item>
                    <list-item>
                      <p>Framework aligned with roles and competences as per the European eCompetence Framework</p>
                    </list-item>
                    <list-item>
                      <p>Use of framework descriptions to determine skill level for each role [<xref ref-type="bibr" rid="ref63">63</xref>]</p>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Model 1: mission and main tasks described for 3 main profiles of health care workers (ie, health, nonhealth, and IT)</p>
                    </list-item>
                    <list-item>
                      <p>Model 2: 52 competencies grouped into 6 domains, where each competency has a description, and a set of associated knowledge and skill, according to 5 proficiency levels</p>
                    </list-item>
                  </list>
                </td>
              </tr>
              <tr valign="top">
                <td>Staggers (2001) [<xref ref-type="bibr" rid="ref31">31</xref>]</td>
                <td>Not specified</td>
                <td>Nurses; in-service</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Literature review</p>
                    </list-item>
                    <list-item>
                      <p>Consensus with experts</p>
                    </list-item>
                  </list>
                </td>
                <td>304 competencies grouped into 3 categories for each level of practice</td>
              </tr>
              <tr valign="top">
                <td>Staggers (2002) [<xref ref-type="bibr" rid="ref32">32</xref>]</td>
                <td>Not specified</td>
                <td>Nurses; in-service</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Follow-up from Staggers (2001) [<xref ref-type="bibr" rid="ref31">31</xref>]</p>
                    </list-item>
                    <list-item>
                      <p>3 Delphi rounds were conducted</p>
                    </list-item>
                  </list>
                </td>
                <td>281 competencies grouped into 3 categories for each level of practice</td>
              </tr>
              <tr valign="top">
                <td>Thye (2018) [<xref ref-type="bibr" rid="ref54">54</xref>]</td>
                <td>International; not specified</td>
                <td>All HCPs including admin and IT support staff; preservice</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Mapped competency areas from Hubner (2018) [<xref ref-type="bibr" rid="ref36">36</xref>] and HITCOMP [<xref ref-type="bibr" rid="ref41">41</xref>]</p>
                    </list-item>
                    <list-item>
                      <p>Survey was sent to HCPs</p>
                    </list-item>
                  </list>
                </td>
                <td>33 competency areas identified, and the 10 most relevant interprofessional areas are listed</td>
              </tr>
              <tr valign="top">
                <td>Trangenstein (2009) [<xref ref-type="bibr" rid="ref43">43</xref>]</td>
                <td>Not specified</td>
                <td>Nurse scholars; in-service</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Literature review</p>
                    </list-item>
                    <list-item>
                      <p>Discussion and consensus</p>
                    </list-item>
                  </list>
                </td>
                <td>7 competency domains sorted according to nursing level of practice</td>
              </tr>
              <tr valign="top">
                <td>Van Houwelingen (2016) [<xref ref-type="bibr" rid="ref53">53</xref>]</td>
                <td>Not specified; remote care</td>
                <td>Nurses; preservice</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Survey with competencies was sent to participants</p>
                    </list-item>
                    <list-item>
                      <p>Delphi study (4 rounds)</p>
                    </list-item>
                  </list>
                </td>
                <td>52 competencies organized into 3 categories, where skills are further subdivided into 5 domains</td>
              </tr>
              <tr valign="top">
                <td>Westra and Delaney (2008) [<xref ref-type="bibr" rid="ref44">44</xref>]</td>
                <td>Not specified</td>
                <td>Nurse leaders; in-service</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Literature review</p>
                    </list-item>
                    <list-item>
                      <p>Delphi study</p>
                    </list-item>
                  </list>
                </td>
                <td>92 competency areas are grouped into 3 categories</td>
              </tr>
            </tbody>
          </table>
          <table-wrap-foot>
            <fn id="table2fn1">
              <p><sup>a</sup>AHIEC: Australian Health Informatics Education Council.</p>
            </fn>
            <fn id="table2fn2">
              <p><sup>b</sup>HCP: health care professional.</p>
            </fn>
            <fn id="table2fn3">
              <p><sup>c</sup>IT: information technology.</p>
            </fn>
            <fn id="table2fn4">
              <p><sup>d</sup>AFMC: Association of Faculties of Medicine of Canada.</p>
            </fn>
            <fn id="table2fn5">
              <p><sup>e</sup>HITCOMP: Health Information Technology Competencies.</p>
            </fn>
            <fn id="table2fn6">
              <p><sup>f</sup>IMIA: International Medical Informatics Association.</p>
            </fn>
            <fn id="table2fn7">
              <p><sup>g</sup>BMHI: biomedical and health informatics.</p>
            </fn>
          </table-wrap-foot>
        </table-wrap>
      </sec>
      <sec>
        <title>Evolution of Frameworks</title>
        <p>The digital health competency frameworks have drawn upon each other and have incrementally advanced the recommendations made in this area, as presented in <xref rid="figure2" ref-type="fig">Figures 2</xref> and <xref rid="figure3" ref-type="fig">3</xref>. The initial work of Staggers et al [<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref32">32</xref>], which targeted nurses at 4 levels of practice, has been reproduced and adapted to suit different nursing roles (eg, nurse leaders, nurse practitioners) [<xref ref-type="bibr" rid="ref22">22</xref>,<xref ref-type="bibr" rid="ref44">44</xref>], health professions (eg, dietitians) [<xref ref-type="bibr" rid="ref45">45</xref>], and even geographical settings (eg, Taiwan, Canada; <xref rid="figure2" ref-type="fig">Figure 2</xref>) [<xref ref-type="bibr" rid="ref37">37</xref>,<xref ref-type="bibr" rid="ref48">48</xref>]. In another instance, to propose competencies for nurse leaders, Collins et al [<xref ref-type="bibr" rid="ref46">46</xref>] expanded and reorganized competency categories from Westra and Delaney [<xref ref-type="bibr" rid="ref44">44</xref>], which initially drew inspiration from the framework by Staggers et al [<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref32">32</xref>]. The framework by Staggers et al [<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref32">32</xref>] was updated 10 years later by Chang et al [<xref ref-type="bibr" rid="ref21">21</xref>] with 42 new competencies.</p>
        <p>Another commonly referenced framework is that by Egbert et al (<xref rid="figure3" ref-type="fig">Figure 3</xref>) [<xref ref-type="bibr" rid="ref33">33</xref>,<xref ref-type="bibr" rid="ref34">34</xref>]. This framework identified 24 core competency areas and conducted a survey with experts to rank the most relevant competency areas for nurses in Austria, Switzerland, and Germany. The same survey with 24 core competency areas was then sent to multiple countries to put forth international recommendations for nursing informatics, widely known as the TIGER framework [<xref ref-type="bibr" rid="ref35">35</xref>,<xref ref-type="bibr" rid="ref36">36</xref>]. The TIGER framework grouped the core competency areas into 6 overarching domains (ie, data, information and knowledge, information exchange and information sharing, ethics and legal issues, systems life cycle management, management in informatics, biostatistics, and medical technology) and ranked the most relevant competencies for nursing internationally. Subsequently, the TIGER framework prompted its 2.0 version to include a wider spectrum of health care workers [<xref ref-type="bibr" rid="ref52">52</xref>], and inspired the work by Thye et al [<xref ref-type="bibr" rid="ref54">54</xref>] where interprofessional competencies were identified.</p>
        <fig id="figure2" position="float">
          <label>Figure 2</label>
          <caption>
            <p>Digital health competency frameworks adapted from Staggers framework.</p>
          </caption>
          <graphic xlink:href="jmir_v22i11e22706_fig2.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
        </fig>
        <p>One framework that was accessible through an open-source internet-based database is the HITCOMP Tool and Repository [<xref ref-type="bibr" rid="ref41">41</xref>]. HITCOMP was produced by the eHealth Workforce Development Workgroup as part of the EU*US eHealth Work Project. Its overall goal was to map, quantify, and project the needs of a digitally competent workforce [<xref ref-type="bibr" rid="ref64">64</xref>]. This tool covers the digital competencies required in acute care settings for 5 broad roles of health care workers, similar to the TIGER framework version 2.0 (ie, direct patient care; administration; engineering or information, communication, and technology; informatics; and research or biomedicine) [<xref ref-type="bibr" rid="ref52">52</xref>]. In comparison with the other included frameworks, the HITCOMP framework has the highest number of competencies at 1025.</p>
        <p>Other frameworks that inspired the development of subsequent frameworks include the IMIA [<xref ref-type="bibr" rid="ref49">49</xref>], which was adapted by the AHIEC [<xref ref-type="bibr" rid="ref57">57</xref>] to create national informatics standards for Australian health professionals, health informaticians, and specialists; the frameworks by Barakat et al [<xref ref-type="bibr" rid="ref50">50</xref>] and the Academy of Medical Royal Colleges [<xref ref-type="bibr" rid="ref59">59</xref>], which were adapted by Van Houwelingen et al [<xref ref-type="bibr" rid="ref53">53</xref>] to develop a telehealth framework aimed at nurses; and the telepsychiatry framework by Hilty et al [<xref ref-type="bibr" rid="ref60">60</xref>], which laid the foundation for telebehavioral health competencies by Maheu et al [<xref ref-type="bibr" rid="ref39">39</xref>].</p>
        <fig id="figure3" position="float">
          <label>Figure 3</label>
          <caption>
            <p>Development of recent digital health competency frameworks. HITCOMP: Health Information Technology Competencies; TIGER: Technology Informatics Guiding Education Reform.</p>
          </caption>
          <graphic xlink:href="jmir_v22i11e22706_fig3.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
        </fig>
      </sec>
      <sec>
        <title>Digital Health Competencies and Categories</title>
        <p>Across the included digital health competency frameworks, the number of competency categories, subcategories, and competencies ranged from 3 to 33, 10 to 39, and 15 to 1025, respectively. The wide range of reported competencies reflects the scale and specificity of the frameworks. For example, the framework with 15 competencies was focused on telepsychiatry training for psychiatry residents [<xref ref-type="bibr" rid="ref51">51</xref>], while a framework with 318 competencies was intended for nurses at 4 different levels of practice [<xref ref-type="bibr" rid="ref21">21</xref>]. Frameworks with multiple categories or subcategories had a larger number of competencies. For example, the eHealth competency framework by the Academy of Medical Royal Colleges presented 20 categories and included 418 competencies [<xref ref-type="bibr" rid="ref59">59</xref>].</p>
        <p>The primary objective of the frameworks was to guide the development of digital health curricula or training initiatives. Thus, 20 frameworks listed specific competencies (eg, knows how to use medical information systems for retrieval of patient data) [<xref ref-type="bibr" rid="ref48">48</xref>], 6 frameworks cited case studies or provided examples for integration of competencies into curricula or training programs [<xref ref-type="bibr" rid="ref33">33</xref>-<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref45">45</xref>,<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref52">52</xref>,<xref ref-type="bibr" rid="ref58">58</xref>], and 3 frameworks ranked the most relevant competency areas, while the remaining 2 frameworks proposed only broad competency domains. Furthermore, in 12 frameworks, proficiency level in a digital health area or competency was presented according to the hierarchy of a profession or according to the depth of a skill that can be acquired by a health care worker role. For example, Chang et. al [<xref ref-type="bibr" rid="ref21">21</xref>] presented competencies according to nursing staff seniority level (ie, a beginning nurse, an experienced nurse, an informatics specialist, an informatics innovator). Conversely, AHIEC assigned each competency a level of 1 to 6 (ie, 1: Remembering; 2: Understanding; 3: Applying; 4: Analyzing; 5: Evaluating; 6: Creating), according to the revised Taxonomy of Learning Domain objectives by Bloom, to indicate the depth of a skill that can be acquired by a health care worker role [<xref ref-type="bibr" rid="ref57">57</xref>].</p>
        <p>In addition, the structure of the included digital health competency frameworks varied. Competencies were organized either based on broad informatics categories (ie, computer skills, informatics knowledge, informatics skills) [<xref ref-type="bibr" rid="ref21">21</xref>,<xref ref-type="bibr" rid="ref22">22</xref>,<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref32">32</xref>,<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref44">44</xref>,<xref ref-type="bibr" rid="ref45">45</xref>,<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref53">53</xref>] or a combination of informatics and noninformatics categories (ie, information systems concepts, management concepts, ethical or legal concepts) [<xref ref-type="bibr" rid="ref38">38</xref>,<xref ref-type="bibr" rid="ref41">41</xref>,<xref ref-type="bibr" rid="ref46">46</xref>,<xref ref-type="bibr" rid="ref59">59</xref>-<xref ref-type="bibr" rid="ref61">61</xref>] or based on health care worker roles (ie, communicator, collaborator, professional) [<xref ref-type="bibr" rid="ref33">33</xref>-<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref52">52</xref>,<xref ref-type="bibr" rid="ref54">54</xref>,<xref ref-type="bibr" rid="ref55">55</xref>]. Alternatively, competencies were sorted according to learning outcomes or statements [<xref ref-type="bibr" rid="ref37">37</xref>,<xref ref-type="bibr" rid="ref39">39</xref>,<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref43">43</xref>,<xref ref-type="bibr" rid="ref47">47</xref>,<xref ref-type="bibr" rid="ref49">49</xref>,<xref ref-type="bibr" rid="ref50">50</xref>,<xref ref-type="bibr" rid="ref56">56</xref>-<xref ref-type="bibr" rid="ref58">58</xref>]. For example, the national guideline for Canadian registered nurses sorted competencies according to 3 overarching statements: (1) uses relevant information and knowledge to support the delivery of evidence-informed patient or client care; (2) uses IT in accordance with professional and regulatory standards and workplace policies; and (3) uses IT in the delivery of patient or client care [<xref ref-type="bibr" rid="ref37">37</xref>].</p>
        <p>Through thematic analysis, we were able to classify the majority of the competency categories presented in the frameworks into 28 domains. These domains are defined in <xref ref-type="boxed-text" rid="box1">Textbox 1</xref>, details of the analysis are provided in <xref ref-type="supplementary-material" rid="app7">Multimedia Appendix 7</xref> [<xref ref-type="bibr" rid="ref45">45</xref>], and results of the analysis is presented in <xref ref-type="supplementary-material" rid="app8">Multimedia Appendix 8</xref>. Competencies relating to the following domains were found to be prevalent in at least half of the included frameworks: informatics concepts and processes (22/30, 73%); health information and records management (19/30, 63%); communication (19/30, 63%); ethics, legal, or regulations (18/30, 60%); privacy and security (17/30, 57%); technical knowledge and support (15/30, 50%); and clinical care delivery (15/30, 50%). Conversely, competencies relating to medicines management (2/30, 7%) [<xref ref-type="bibr" rid="ref41">41</xref>,<xref ref-type="bibr" rid="ref59">59</xref>]; attitudes toward IT (4/30, 13%) [<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref58">58</xref>,<xref ref-type="bibr" rid="ref60">60</xref>]; IT advocacy (5/30, 17%) [<xref ref-type="bibr" rid="ref21">21</xref>,<xref ref-type="bibr" rid="ref22">22</xref>,<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref55">55</xref>,<xref ref-type="bibr" rid="ref60">60</xref>]; and public health (5/30, 17%) [<xref ref-type="bibr" rid="ref41">41</xref>,<xref ref-type="bibr" rid="ref49">49</xref>,<xref ref-type="bibr" rid="ref52">52</xref>,<xref ref-type="bibr" rid="ref54">54</xref>,<xref ref-type="bibr" rid="ref55">55</xref>] were found to be uncommon in digital health competency frameworks. Of the 28 identified domains, 20 (71%) were present in at least one-third of the frameworks (<xref ref-type="supplementary-material" rid="app8">Multimedia Appendix 8</xref>).</p>
        <boxed-text id="box1" position="float">
          <title>Digital health competency domains identified from the included frameworks.</title>
          <p>Administration and general management</p>
          <list list-type="bullet">
            <list-item>
              <p>Use of administrative information technology (IT) applications to perform tasks and procedures, such as planning and delivery of services, business workflows, and human resource management</p>
            </list-item>
          </list>
          <p>Analysis</p>
          <list list-type="bullet">
            <list-item>
              <p>Use of IT systems to perform analysis of data, including data visualization, evaluation, and reporting</p>
            </list-item>
          </list>
          <p>Attitudes toward IT</p>
          <list list-type="bullet">
            <list-item>
              <p>Attitudes and cultural awareness toward the use of IT in patient care</p>
            </list-item>
          </list>
          <p>Clinical care delivery</p>
          <list list-type="bullet">
            <list-item>
              <p>Utilization of IT for the support of clinical care and practice, including use of assistive technologies and electronic test requesting</p>
            </list-item>
          </list>
          <p>Communication</p>
          <list list-type="bullet">
            <list-item>
              <p>Use of digital communications (eg, social media, email, etc) to enhance interpersonal skills and to aid in care delivery and decision-making process</p>
            </list-item>
          </list>
          <p>Decision support</p>
          <list list-type="bullet">
            <list-item>
              <p>Use of IT for clinical practice decision support</p>
            </list-item>
          </list>
          <p>Documentation</p>
          <list list-type="bullet">
            <list-item>
              <p>Use of IT for appropriate documentation tasks and processes, including knowledge of coding and terminologies</p>
            </list-item>
          </list>
          <p>Education and training</p>
          <list list-type="bullet">
            <list-item>
              <p>Use of IT in education and training, including e-Learning, mobile learning, and simulation</p>
            </list-item>
          </list>
          <p>Ethics, legal, or regulations</p>
          <list list-type="bullet">
            <list-item>
              <p>Knowledge of ethical, regulatory, compliance, and legal requirements relating to health IT</p>
            </list-item>
          </list>
          <p>Financial management</p>
          <list list-type="bullet">
            <list-item>
              <p>Knowledge of financial and account management relating to IT applications, including billing and fiscal aspects</p>
            </list-item>
          </list>
          <p>Health information and records management</p>
          <list list-type="bullet">
            <list-item>
              <p>Ability to access, collect, store, share, and manage digital health information; use of eHealth records; information and knowledge management</p>
            </list-item>
          </list>
          <p>Health care quality and safety</p>
          <list list-type="bullet">
            <list-item>
              <p>Ensuring or improving the quality and safety of health care services with the use of IT</p>
            </list-item>
          </list>
          <p>Imaging</p>
          <list list-type="bullet">
            <list-item>
              <p>Knowledge of biomedical imaging digital technologies</p>
            </list-item>
          </list>
          <p>Informatics concepts and processes</p>
          <list list-type="bullet">
            <list-item>
              <p>Knowledge and skills in computer basics, information systems, and general health IT use</p>
            </list-item>
          </list>
          <p>Integration and interoperability</p>
          <list list-type="bullet">
            <list-item>
              <p>Knowledge of integrated health IT applications, health information exchange, and interoperability standards, including coordination and collaboration aspects</p>
            </list-item>
          </list>
          <p>IT advocacy</p>
          <list list-type="bullet">
            <list-item>
              <p>Play an active role in promoting the use of IT in health care environments</p>
            </list-item>
          </list>
          <p>Leadership and executive management</p>
          <list list-type="bullet">
            <list-item>
              <p>Providing or enhancing executive leadership skills relating to the use of IT, including setting direction, strategic management, change management, stakeholder management, and governance</p>
            </list-item>
          </list>
          <p>Medicines management</p>
          <list list-type="bullet">
            <list-item>
              <p>Management of digital medication records and use of order entry</p>
            </list-item>
          </list>
          <p>Patient access and engagement</p>
          <list list-type="bullet">
            <list-item>
              <p>Promoting use of IT applications among patients and supporting or empowering patients for self-management, including patient access to patient health records</p>
            </list-item>
          </list>
          <p>Privacy and security</p>
          <list list-type="bullet">
            <list-item>
              <p>Ensuring that digital data and health information are protected and kept confidential by following privacy and security procedures</p>
            </list-item>
          </list>
          <p>Project management</p>
          <list list-type="bullet">
            <list-item>
              <p>Knowledge of project management software and associated terminologies</p>
            </list-item>
          </list>
          <p>Public health</p>
          <list list-type="bullet">
            <list-item>
              <p>Use of IT to inform public health strategies</p>
            </list-item>
          </list>
          <p>Remote care</p>
          <list list-type="bullet">
            <list-item>
              <p>Provision of care at a distance, including telehealth care, eHealth, mobile health, and related fields</p>
            </list-item>
          </list>
          <p>Research</p>
          <list list-type="bullet">
            <list-item>
              <p>Appropriate use of IT for research support and innovations</p>
            </list-item>
          </list>
          <p>Risk management</p>
          <list list-type="bullet">
            <list-item>
              <p>Managing IT-related risks</p>
            </list-item>
          </list>
          <p>Systems implementation</p>
          <list list-type="bullet">
            <list-item>
              <p>Knowledge and skills about IT systems development, management, and implementation</p>
            </list-item>
          </list>
          <p>Technical knowledge and support</p>
          <list list-type="bullet">
            <list-item>
              <p>Knowledge of technical aspects of IT systems, including software applications, testing, applied computer science, and IT maintenance and support capabilities</p>
            </list-item>
          </list>
        </boxed-text>
      </sec>
    </sec>
    <sec sec-type="discussion">
      <title>Discussion</title>
      <sec>
        <title>Principal Findings</title>
        <p>Of the 30 digital health competency frameworks, 14 solely targeted nursing staff. The frameworks predominantly originated from high-income countries and were developed based on literature reviews, followed by expert discussions or a Delphi approach. More than half of the included frameworks, especially those providing national-level recommendations, were from gray literature sources. Most frameworks were published between 2016 and 2019, highlighting the growing interest in digital health competencies in recent years.</p>
        <p>The purpose of the retrieved digital health competency frameworks and the intended audience was clearly stated in most frameworks. The earliest frameworks and almost half of all the included frameworks were meant for nurses. This could be due to the significantly larger proportion of nurses in the health workforce [<xref ref-type="bibr" rid="ref65">65</xref>]. Nurses play a crucial role in supporting health care environments by being a constant point of contact between patients and doctors; thus, there are various aspects of digital capabilities that are required of them (eg, using staff scheduling systems, extracting data from clinical systems, navigating decision support systems) [<xref ref-type="bibr" rid="ref22">22</xref>]. These nursing-focused frameworks have inspired subsequent works for other health care workers. For example, several competency areas subsumed under broad areas for nurses in the TIGER framework [<xref ref-type="bibr" rid="ref36">36</xref>] were marked as standalone competency areas (ie, communication, legal issues, interoperability and integration, and life cycle management) for a wider spectrum of health care workers in version 2.0 of the TIGER framework [<xref ref-type="bibr" rid="ref52">52</xref>]. Notably, only one framework was found for allied health professionals (ie, dietitians) [<xref ref-type="bibr" rid="ref45">45</xref>], which highlights the perceived lack of interest in educating and training this group of workers in digital health. However, the Health Informatics Society of Australia, now known as the Australasian Institute of Digital Health, highlighted the need to focus on allied health care workers as their involvement is becoming increasingly important in decision making to improve patient care and health outcomes [<xref ref-type="bibr" rid="ref66">66</xref>]. Furthermore, although there were frameworks for doctors and medical students collectively, only one framework was intended solely for undergraduate medical education. The framework was a national guideline for medical students in Canada briefly describing 25 eHealth competencies [<xref ref-type="bibr" rid="ref55">55</xref>]. Medical practice relies heavily on communication, which is now achieved through various digital means; thus, the skills to utilize a range of digital technologies should be comprehensive and included in medical education [<xref ref-type="bibr" rid="ref67">67</xref>]. Moreover, with the COVID-19 pandemic, doctors are required to handle patient consultations digitally [<xref ref-type="bibr" rid="ref11">11</xref>]. A 2018 survey conducted by European Medical Students’ Association revealed that a majority of medical students rated their eHealth skills to be “poor” or “very poor” and desired for adequate digital health literacy [<xref ref-type="bibr" rid="ref14">14</xref>].</p>
        <p>Most of the included frameworks are useful for application in education or practice, mainly owing to the specificity of competencies, the organization of competencies according to proficiency levels or health care worker roles, and the illustration of case studies and examples to be applicable to various settings. On the other hand, frameworks by Trangenstein et al [<xref ref-type="bibr" rid="ref43">43</xref>] and Jidkov et al [<xref ref-type="bibr" rid="ref40">40</xref>] presented only broad competency themes, as it was believed that exhaustive lists of competencies could lead to poor adoption [<xref ref-type="bibr" rid="ref40">40</xref>]. As the included digital health competency frameworks were heterogeneous in purpose, audience, and setting, it is challenging to determine a single framework as exemplary. Nevertheless, HITCOMP, which was developed via an iterative methodology, was found to be the most comprehensive framework, covering 21 out of the 28 identified competency domains, listing 1025 competencies, and targeting a wide audience of health care workers and medical specialties [<xref ref-type="bibr" rid="ref41">41</xref>].</p>
        <p>The key thrust of work in this area involves competencies related to informatics, followed by eHealth, telehealth or telebehavioral or telepsychiatry, digital capability, and health IT competencies. This distinction may be superficial, given that the definitions and terminologies seem to overlap across frameworks and the nomenclatural differences do not necessarily convey differences in competencies. For example, the interprofessional eHealth framework developed by Thye et al [<xref ref-type="bibr" rid="ref54">54</xref>] utilized a range of informatics frameworks [<xref ref-type="bibr" rid="ref33">33</xref>,<xref ref-type="bibr" rid="ref41">41</xref>,<xref ref-type="bibr" rid="ref49">49</xref>].</p>
        <p>Although frameworks often drew upon each other, there were considerable variations among the identified competencies. The Egbert et al [<xref ref-type="bibr" rid="ref33">33</xref>,<xref ref-type="bibr" rid="ref34">34</xref>] framework identified the 5 most relevant competency areas (out of 24) for 5 nursing roles in Austria, Germany, and Switzerland. The TIGER framework [<xref ref-type="bibr" rid="ref35">35</xref>,<xref ref-type="bibr" rid="ref36">36</xref>] used the same competency areas and methodology as Egbert et al [<xref ref-type="bibr" rid="ref33">33</xref>,<xref ref-type="bibr" rid="ref34">34</xref>] and additionally reached out to experts worldwide for their inputs. The resulting relevant competency areas for a nurse in an IT management role, for example, varied considerably between both frameworks. For this role, competency areas, <italic>risk management</italic> and <italic>project management</italic>, ranked the top 5 internationally in the TIGER framework [<xref ref-type="bibr" rid="ref35">35</xref>,<xref ref-type="bibr" rid="ref36">36</xref>]; however, it was only relevant in 1 out of 3 countries in the Egbert et al [<xref ref-type="bibr" rid="ref34">34</xref>] framework. In addition, eHealth, telematics, and telehealth, which were ranked as top 5 by Egbert et al [<xref ref-type="bibr" rid="ref34">34</xref>] for 2 out of 3 countries (ie, Germany and Austria), did not make it to the top 10 list in the TIGER framework [<xref ref-type="bibr" rid="ref35">35</xref>,<xref ref-type="bibr" rid="ref36">36</xref>]. This suggests that the IT management role for nurses could be defined differently depending on each setting. Hence, a clear definition of the role is important to match the appropriate competency skills to a health care worker role.</p>
        <p>In our thematic analysis of the competencies included in the retrieved frameworks, we identified 28 competency domains. The most prevalent domain relates to competencies aimed at providing knowledge on informatics concepts and processes. Examples of these include basic computer knowledge, information systems concepts, and principles of informatics, which are fundamental skills to health care workers intending to maximize the use of digital technologies. The other common domains included the ability of health care workers to manage data from health information systems and records and to be well-versed in digital communications. Most of the health-related data today exist in digital form; therefore, it is imperative for health care workers to be able to understand the purpose, basic structures, use, and storage of electronic health records (EHRs). In addition, as digital health entails new forms of communication (eg, virtual consultations, email, chatbots), it is imperative for health care workers to be able to relate information accurately yet efficiently, timely, and delicately to patients, colleagues, and other collaborating stakeholders [<xref ref-type="bibr" rid="ref68">68</xref>]. Furthermore, the rise in the adoption and utilization of digital technologies has spurred new issues relating to the use of IT [<xref ref-type="bibr" rid="ref69">69</xref>], which corresponds to the next two common domains of competencies (ie, ethics, legal, or regulations, and privacy and security). These domains stress the importance of health care workers’ adherence to legal and regulatory requirements and to keep up to date with privacy and security policies pertaining to the appropriate use of digital technologies.</p>
        <p>Some categories that were found in more recent frameworks, such as attitudes toward the use of IT, medication and prescription, IT advocacy, and public health, reflect the emerging trends in digital capabilities required by health care workers. For example, with the widespread adoption of EHRs and e-prescribing being a key functionality, it is imperative for physicians to be able to perform prescribing tasks efficiently and adapt to new features as systems continually evolve [<xref ref-type="bibr" rid="ref70">70</xref>]. In addition, as digital technologies have an increasing role in the management of health of communities and populations, frameworks have also started to incorporate competencies related to public health [<xref ref-type="bibr" rid="ref71">71</xref>]. Similarly, the acceptance of IT and its incorporation into everyday practice hinges on health care workers advocating for their use and being mindful of contextual factors and beliefs that would enable their use in different settings, such as high-income and low- and middle-income countries (LMICs). Other distinct domains such as leadership, administrative, managerial, and financial bring to attention that a digitally competent workforce should also be able to utilize technologies to oversee organizational-level aspects. It was also noted that competencies related to artificial intelligence, robotics, and social media, which are very relevant in current times, were not explicitly mentioned in the included frameworks [<xref ref-type="bibr" rid="ref5">5</xref>,<xref ref-type="bibr" rid="ref9">9</xref>,<xref ref-type="bibr" rid="ref72">72</xref>]. One possible explanation could be that some of these are subsumed under broader categories, for example, competencies regarding the use of social media could be part of the <italic>communication</italic> category, or that these digital areas have yet to be covered in digital health competency frameworks.</p>
        <p>From this synthesis of digital health competency frameworks, we would like to propose recommendations for the development of future frameworks (<xref ref-type="boxed-text" rid="box2">Textbox 2</xref>). First, an iterative methodology that includes literature review and consultations with local and international experts is ideal for a comprehensive framework. Second, it is encouraged for upcoming frameworks to explore competency areas that appeared in more recent frameworks, to cover upcoming digital health areas (ie, health apps, artificial intelligence, autonomous decision-support systems), and to be open to future revisions to be up to date with technological developments. For example, HITCOMP is projected to continue mapping and aligning competencies with the curriculum and other major initiatives [<xref ref-type="bibr" rid="ref64">64</xref>]. Finally, the lack of a comprehensive and international framework applicable to allied health professionals and LMICs warrants the development of frameworks that include these populations and settings. For example, only the TIGER framework includes case studies of LMICs, such as China, India, and Nigeria [<xref ref-type="bibr" rid="ref73">73</xref>].</p>
        <boxed-text id="box2" position="float">
          <title>Recommendations for the development of digital health competency frameworks.</title>
          <p>Methodology:</p>
          <list list-type="bullet">
            <list-item>
              <p>Literature review, followed by consultations or Delphi study with local experts, followed by engagement with international experts</p>
            </list-item>
          </list>
          <p>Content:</p>
          <list list-type="bullet">
            <list-item>
              <p>Explore new competency areas that appeared in recent frameworks (ie, attitudes and advocacy toward the use of information technology (IT), medication management, public health)</p>
            </list-item>
            <list-item>
              <p>Update competencies based on technological innovations and adoption and emerging evidence (ie, health apps, artificial intelligence, autonomous decision-support systems)</p>
            </list-item>
            <list-item>
              <p>Include essential interprofessional competencies (ie, informatics concepts and processes, health information management, communication, ethics, legal, or regulations, and privacy and security)</p>
            </list-item>
          </list>
          <p>Target audience or setting to include:</p>
          <list list-type="bullet">
            <list-item>
              <p>Allied health professionals</p>
            </list-item>
            <list-item>
              <p>Low- and middle-income countries</p>
            </list-item>
          </list>
          <p>Application:</p>
          <list list-type="bullet">
            <list-item>
              <p>Provide case studies of integration into curricula or training programs or examples of application in practice</p>
            </list-item>
          </list>
        </boxed-text>
        <p>The findings from this review can also inform and guide future training initiatives on digital health. When designing an educational or training program, it may not be possible to cover numerous competencies presented in a framework; rather, the program should focus on a specific set of competencies suitable for a particular group of health care workers, role, level of seniority, geographical, and health care setting. However, the identified competency domains prevalent in more than half of the included frameworks (ie, informatics concepts and processes, health information management, communication, ethics, legal, or regulations, and privacy and security) should be considered essential interprofessional competencies and thus should be incorporated into training and education efforts for any health care worker group. In addition, several digital competencies presented in the included frameworks may already be covered within the existing curriculum. For example, competencies within the <italic>Analysis</italic> and <italic>Research</italic> category may have been integrated within epidemiology training and evidence-based medicine education, respectively. Therefore, educators should consider integrating digital health training within existing parts of the curriculum and teaching it in an applied manner as much as possible. For example, the use of EHRs could be incorporated into the internal medicine curriculum.</p>
      </sec>
      <sec>
        <title>Strengths and Limitations</title>
        <p>To our knowledge, this is the first consolidation and analysis of existing digital health competency frameworks regardless of the role of health care workers. We performed a thorough search, including several databases and gray literature sources. Our analysis also provides a comprehensive overview of the types of competencies presented in digital health competency frameworks, which will aid in the training and education of health care workers to be digitally competent in relevant areas. Some weaknesses must be kept in mind when interpreting the findings of this review. Although a substantial number of frameworks from gray literature were included, some could have been missed, potentially national guidelines and standards from LMICs. In addition, when performing the thematic analysis, there were frameworks with vague competency categories and overlaps among some categories, leading to differences in opinions during the classification process. However, the 2 reviewers used their expertise to develop and clearly define the domains and allocate categories from frameworks into these domains, first independently and then through a consensus discussion, to reduce bias and classify as appropriately as possible. Although the reviewers aimed to make the classification process as transparent and reproducible as possible, it must be noted that there could be alternate ways of interpreting and classifying and that categorization may differ in the future with the new advances in digital health.</p>
      </sec>
      <sec>
        <title>Conclusions</title>
        <p>Of the 30 frameworks included in this scoping review, a majority target nurses, originate from high-income countries, and have been developed using an iterative approach. Our analysis of digital health competency frameworks can help inform the development of future digital health training programs for health care workers. Existing frameworks largely focus on the development of basic IT skills, proficiency in managing health-related information and digital communications, and awareness of ethical, legal, privacy, and security implications relating to IT. Future frameworks and training programs need to take into consideration the evolving nature of digital health and have to be able to incorporate upcoming digital trends, such as artificial intelligence and robotics. There is also a need for frameworks focusing on LMICs, medical students, and allied health professionals.</p>
      </sec>
    </sec>
  </body>
  <back>
    <app-group>
      <supplementary-material id="app1">
        <label>Multimedia Appendix 1</label>
        <p>Inclusion and exclusion criteria.</p>
        <media xlink:href="jmir_v22i11e22706_app1.docx" xlink:title="DOCX File , 50 KB"/>
      </supplementary-material>
      <supplementary-material id="app2">
        <label>Multimedia Appendix 2</label>
        <p>Search strategy for Medical Literature Analysis and Retrieval System Online (MEDLINE).</p>
        <media xlink:href="jmir_v22i11e22706_app2.docx" xlink:title="DOCX File , 48 KB"/>
      </supplementary-material>
      <supplementary-material id="app3">
        <label>Multimedia Appendix 3</label>
        <p>Keywords used for searching gray literature.</p>
        <media xlink:href="jmir_v22i11e22706_app3.docx" xlink:title="DOCX File , 52 KB"/>
      </supplementary-material>
      <supplementary-material id="app4">
        <label>Multimedia Appendix 4</label>
        <p>List of organizations whose websites were searched.</p>
        <media xlink:href="jmir_v22i11e22706_app4.docx" xlink:title="DOCX File , 48 KB"/>
      </supplementary-material>
      <supplementary-material id="app5">
        <label>Multimedia Appendix 5</label>
        <p>Data extraction form.</p>
        <media xlink:href="jmir_v22i11e22706_app5.docx" xlink:title="DOCX File , 48 KB"/>
      </supplementary-material>
      <supplementary-material id="app6">
        <label>Multimedia Appendix 6</label>
        <p>Details of included studies.</p>
        <media xlink:href="jmir_v22i11e22706_app6.docx" xlink:title="DOCX File , 68 KB"/>
      </supplementary-material>
      <supplementary-material id="app7">
        <label>Multimedia Appendix 7</label>
        <p>Allocation of competency categories or themes from included frameworks into overarching competency domains.</p>
        <media xlink:href="jmir_v22i11e22706_app7.docx" xlink:title="DOCX File , 76 KB"/>
      </supplementary-material>
      <supplementary-material id="app8">
        <label>Multimedia Appendix 8</label>
        <p>Competency domains prevalent across 30 digital health competency frameworks.</p>
        <media xlink:href="jmir_v22i11e22706_app8.png" xlink:title="PNG File , 300 KB"/>
      </supplementary-material>
    </app-group>
    <glossary>
      <title>Abbreviations</title>
      <def-list>
        <def-item>
          <term id="abb1">AHIEC</term>
          <def>
            <p>Australian Health Informatics Council</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb2">CINAHL</term>
          <def>
            <p>Cumulative Index to Nursing and Allied Health Literature</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb3">EHR</term>
          <def>
            <p>electronic health record</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb4">EMBASE</term>
          <def>
            <p>Excerpta Medica dataBASE</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb5">ERIC</term>
          <def>
            <p>Education Resources Information Centre</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb6">HITCOMP</term>
          <def>
            <p>Health Information Technology Competencies</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb7">IMIA</term>
          <def>
            <p>International Medical Informatics Association</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb8">IT</term>
          <def>
            <p>information technology</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb9">LMIC</term>
          <def>
            <p>low- and middle-income country</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb10">MEDLINE</term>
          <def>
            <p>Medical Literature Analysis and Retrieval System Online</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb11">NHS</term>
          <def>
            <p>National Health Services</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb12">TIGER</term>
          <def>
            <p>Technology Informatics Guiding Education Reform</p>
          </def>
        </def-item>
      </def-list>
    </glossary>
    <ack>
      <p>The authors thank Ms Yasmin Lynda Munro from the Lee Kong Chian School of Medicine, Medical Library, for assistance in formulating the search strategy. They would also like to thank Ms Laura Martinengo, Ms Selina Poon, Ms Christina Tan, Mr Gerard Dunleavy, and Mr Rishi S Nannan Panday for their assistance with screening articles and data extraction. The authors would like to acknowledge the funding support from the Lee Kong Chian School of Medicine, Nanyang Technological University Singapore. JC’s and LC’s post at Imperial College London is supported by the National Institute for Health Research North West London Applied Research Collaboration.</p>
      <p>This research was supported by funding from the World Health Organization Collaborating Centre for Digital Health and Health Education, provided by the Lee Kong Chian School of Medicine and Nanyang Technological University Singapore, Singapore.</p>
    </ack>
    <fn-group>
      <fn fn-type="con">
        <p>LC conceived the idea for the review and advised on the methodology. NN, DP, BK, and GJ were involved in the literature search, screening, and data extraction. NN and GJ were involved in the thematic analysis. NN analyzed and synthesized the data and drafted the manuscript. JC conceived the idea for the review and supervised the study. All authors reviewed the paper and provided critical inputs.</p>
      </fn>
      <fn fn-type="conflict">
        <p>None declared.</p>
      </fn>
    </fn-group>
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