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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JMIR</journal-id>
      <journal-id journal-id-type="nlm-ta">J Med Internet Res</journal-id>
      <journal-title>Journal of Medical Internet Research</journal-title>
      <issn pub-type="epub">1438-8871</issn>
      <publisher>
        <publisher-name>JMIR Publications</publisher-name>
        <publisher-loc>Toronto, Canada</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
    <article-id pub-id-type="publisher-id">v21i1e9076</article-id>
    <article-id pub-id-type="pmid">31344680</article-id>
    <article-id pub-id-type="doi">10.2196/jmir.9076</article-id>
    <article-categories>
      <subj-group subj-group-type="heading">
        <subject>Review</subject>
      </subj-group>
      <subj-group subj-group-type="article-type">
        <subject>Review</subject>
      </subj-group>
    </article-categories>
    <title-group>
      <article-title>Evaluating Digital Maturity and Patient Acceptability of Real-Time Patient Experience Feedback Systems: Systematic Review</article-title>
    </title-group>
    <contrib-group>
      <contrib contrib-type="editor">
        <name>
          <surname>Eysenbach</surname>
          <given-names>Gunther</given-names>
        </name>
      </contrib>
    </contrib-group>
    <contrib-group>
      <contrib contrib-type="reviewer">
        <name>
          <surname>Brown</surname>
          <given-names>Hilary</given-names>
        </name>
      </contrib>
      <contrib contrib-type="reviewer">
        <name>
          <surname>Kayser</surname>
          <given-names>Lars</given-names>
        </name>
      </contrib>
      <contrib contrib-type="reviewer">
        <name>
          <surname>Wintner</surname>
          <given-names>Lisa</given-names>
        </name>
      </contrib>
      <contrib contrib-type="reviewer">
        <name>
          <surname>Ribeiro</surname>
          <given-names>Nuno</given-names>
        </name>
      </contrib>
      <contrib contrib-type="reviewer">
        <name>
          <surname>Agarwal</surname>
          <given-names>Kanupriya</given-names>
        </name>
      </contrib>
      <contrib contrib-type="reviewer">
        <name>
          <surname>Nault</surname>
          <given-names>Daryl</given-names>
        </name>
      </contrib>
    </contrib-group>
    <contrib-group>
      <contrib contrib-type="author" id="contrib1" corresp="yes">
      <name name-style="western">
        <surname>Khanbhai</surname>
        <given-names>Mustafa</given-names>
      </name>
      <degrees>MBChB, BScHons, MRCS (Ed)</degrees>
      <xref rid="aff1" ref-type="aff">1</xref>
      <address>
        <institution>Centre for Health Policy</institution>
        <institution>Imperial College London</institution>
        <addr-line>10th Floor QEQM Building</addr-line>
        <addr-line>Centre for Health Policy</addr-line>
        <addr-line>London, W2 1NY</addr-line>
        <country>United Kingdom</country>
        <phone>44 02033126428</phone>
        <fax>44 207594184</fax>
        <email>m.khanbhai@imperial.ac.uk</email>
      </address>  
      <ext-link ext-link-type="orcid">http://orcid.org/0000-0002-4434-1785</ext-link></contrib>
      <contrib contrib-type="author" id="contrib2">
        <name name-style="western">
          <surname>Flott</surname>
          <given-names>Kelsey</given-names>
        </name>
        <degrees>BA, MSc</degrees>
        <xref rid="aff1" ref-type="aff">1</xref>
        <ext-link ext-link-type="orcid">http://orcid.org/0000-0002-7835-4322</ext-link>
      </contrib>
      <contrib contrib-type="author" id="contrib3">
        <name name-style="western">
          <surname>Darzi</surname>
          <given-names>Ara</given-names>
        </name>
        <degrees>PC, KBE, FRS, FMedSci, HonFREng</degrees>
        <xref rid="aff1" ref-type="aff">1</xref>
        <ext-link ext-link-type="orcid">http://orcid.org/0000-0001-7815-7989</ext-link>
      </contrib>
      <contrib contrib-type="author" id="contrib4">
        <name name-style="western">
          <surname>Mayer</surname>
          <given-names>Erik</given-names>
        </name>
        <degrees>MBBS, BSc, MRCS, PhD, FRCS (Urol)</degrees>
        <xref rid="aff1" ref-type="aff">1</xref>
        <ext-link ext-link-type="orcid">http://orcid.org/0000-0002-5509-4580</ext-link>
      </contrib>
    </contrib-group>
    <aff id="aff1">
    <label>1</label>
    <institution>Centre for Health Policy</institution>
    <institution>Imperial College London</institution>  
    <addr-line>London</addr-line>
    <country>United Kingdom</country></aff>
    <author-notes>
      <corresp>Corresponding Author: Mustafa Khanbhai 
      <email>m.khanbhai@imperial.ac.uk</email></corresp>
    </author-notes>
    <pub-date pub-type="collection"><month>01</month><year>2019</year></pub-date>
    <pub-date pub-type="epub">
      <day>14</day>
      <month>01</month>
      <year>2019</year>
    </pub-date>
    <volume>21</volume>
    <issue>1</issue>
    <elocation-id>e9076</elocation-id>
    <!--history from ojs - api-xml-->
    <history>
      <date date-type="received">
        <day>28</day>
        <month>9</month>
        <year>2017</year>
      </date>
      <date date-type="rev-request">
        <day>9</day>
        <month>12</month>
        <year>2017</year>
      </date>
      <date date-type="rev-recd">
        <day>24</day>
        <month>4</month>
        <year>2018</year>
      </date>
      <date date-type="accepted">
        <day>24</day>
        <month>9</month>
        <year>2018</year>
      </date>
    </history>
    <!--(c) the authors - correct author names and publication date here if necessary. Date in form ', dd.mm.yyyy' after jmir.org-->
    <copyright-statement>©Mustafa Khanbhai, Kelsey Flott, Ara Darzi, Erik Mayer. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 14.01.2019.</copyright-statement>
    <copyright-year>2019</copyright-year>
    <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
      <p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Journal of Medical Internet Research, is properly cited. The complete bibliographic information, a link to the original publication on http://www.jmir.org/, as well as this copyright and license information must be included.</p>
    </license>  
    <self-uri xlink:href="https://www.jmir.org/2019/1/e9076/" xlink:type="simple"/>
    <abstract>
      <sec sec-type="background">
        <title>Background</title>
        <p>One of the essential elements of a strategic approach to improving patients’ experience is to measure and report on patients’ experiences in real time. Real-time feedback (RTF) is increasingly being collected using digital technology; however, there are several factors that may influence the success of the digital system.</p>
      </sec>
      <sec sec-type="objective">
        <title>Objective</title>
        <p>The aim of this review was to evaluate the digital maturity and patient acceptability of real-time patient experience feedback systems.</p>
      </sec>
      <sec sec-type="methods">
        <title>Methods</title>
        <p>We systematically searched the following databases to identify papers that used digital systems to collect RTF: The Cochrane Library, Global Health, Health Management Information Consortium, Medical Literature Analysis and Retrieval System Online, EMBASE, PsycINFO, Web of Science, and CINAHL. In addition, Google Scholar and gray literature were utilized. Studies were assessed on their digital maturity using a Digital Maturity Framework on the basis of the following 4 domains: capacity/resource, usage, interoperability, and impact. A total score of 4 indicated the highest level of digital maturity.</p>
      </sec>
      <sec sec-type="results">
        <title>Results</title>
        <p>RTF was collected primarily using touchscreens, tablets, and Web-based platforms. Implementation of digital systems showed acceptable response rates and generally positive views from patients and staff. Patient demographics according to RTF responses varied. An overrepresentation existed in females with a white predominance and in patients aged ≥65 years. Of 13 eligible studies, none had digital systems that were deemed to be of the highest level of maturity. Three studies received a score of 3, 2, and 1, respectively. Four studies scored 0 points. While 7 studies demonstrated capacity/resource, 8 demonstrated impact. None of the studies demonstrated interoperability in their digital systems.</p>
      </sec>
      <sec sec-type="conclusions">
        <title>Conclusions</title>
        <p>Patients and staff alike are willing to engage in RTF delivered using digital technology, thereby disrupting previous paper-based feedback. However, a lack of emphasis on digital maturity may lead to ineffective RTF, thwarting improvement efforts. Therefore, given the potential benefits of RTF, health care services should ensure that their digital systems deliver across the digital maturity continuum.</p>
      </sec>
    </abstract>
    <kwd-group>
      <kwd>digital maturity</kwd>
      <kwd>digital technology</kwd>
      <kwd>feedback</kwd>
      <kwd>patient experience</kwd>
      <kwd>real time</kwd>
    </kwd-group></article-meta>
  </front>
  <body>
    <sec sec-type="introduction">
      <title>Introduction</title>
      <sec>
        <title>Background of Patient Experience Feedback</title>
        <p>Alongside measures of clinical effectiveness and safety outcomes, patient experience is increasingly recognized as an important indicator of the quality of health care provision and is frequently cited in health policies [<xref ref-type="bibr" rid="ref1">1</xref>-<xref ref-type="bibr" rid="ref3">3</xref>]. Yet, in practice and research, the concept of patient experience has had varied uses and is often discussed with little more explanation than the term itself [<xref ref-type="bibr" rid="ref4">4</xref>]. In 2011, the English National Health Service (NHS) [<xref ref-type="bibr" rid="ref5">5</xref>] outlined 8 domains that help define patient experience and are critical to patients’ experience of health care services. This has been used as an agreed working definition of patient experience to guide the measurement of patient experience across the NHS.</p>
      </sec>
      <sec>
        <title>Patient Experience Feedback in Real Time</title>
        <p>One of the essential elements of a strategic approach to improving patients’ experience is to measure and report on patients’ experiences to assess progress, strengthen accountability, and identify new opportunities for improving performance [<xref ref-type="bibr" rid="ref6">6</xref>]. Evidence suggests that this can be achieved using real-time feedback (RTF) [<xref ref-type="bibr" rid="ref7">7</xref>]. RTF involves the systematic collection, analysis, and reporting of information from individuals at the point of care [<xref ref-type="bibr" rid="ref8">8</xref>]. Previous studies have found that RTF has the potential to enable health care organizations to respond promptly to patients’ concerns and make timely improvements to services [<xref ref-type="bibr" rid="ref7">7</xref>,<xref ref-type="bibr" rid="ref9">9</xref>-<xref ref-type="bibr" rid="ref11">11</xref>].</p>
      </sec>
      <sec>
        <title>Collecting Real-Time Feedback Using Digital Technology</title>
        <p>With the ability to maximize the scalability and speed of data collection while reducing cost [<xref ref-type="bibr" rid="ref12">12</xref>], digital tools (tablets, kiosks, emailed survey, and websites) are increasingly being utilized to gather patient experience feedback [<xref ref-type="bibr" rid="ref13">13</xref>,<xref ref-type="bibr" rid="ref14">14</xref>], allowing summary results to be reported on an ongoing [<xref ref-type="bibr" rid="ref15">15</xref>] real-time basis. In a recent Cochrane review [<xref ref-type="bibr" rid="ref16">16</xref>], self-administered survey questionnaire responses collected using mobile apps were compared with those collected using other methods, and it was concluded that the delivery of survey questionnaires through apps does not affect data equivalence and can improve data completeness. However, none of the questionnaires evaluated patient experience.</p>
        <p>There is a growing pressure on health care services to embrace digital technologies tosignificantly improve the patient experience [<xref ref-type="bibr" rid="ref17">17</xref>]. With an increase in adoption of digital systems pertaining to RTF, health care services must recognize and overcome the barriers that may hinder successful integration and uptake of such technologies. One of the ways of achieving this is through systematic evaluation and monitoring of digital systems to ensure they operate in the way they are intended and cultivate a better patient experience [<xref ref-type="bibr" rid="ref17">17</xref>]. Digital maturity—the extent to which digital technologies are used as enablers to deliver a high-quality health service—is an emerging concept across developed health care systems [<xref ref-type="bibr" rid="ref17">17</xref>]. Evidence suggests that digital maturity is linked to better outcomes and is indicative of a well-performing organization [<xref ref-type="bibr" rid="ref18">18</xref>]. Evaluating digital systems for digital maturity highlights where gaps exist in maturity, which presents an opportunity to address the specific shortcomings [<xref ref-type="bibr" rid="ref17">17</xref>]. The digital maturity of the systems that are being used to collect RTF has not been previously evaluated. A deeper understanding of the limitations of individual digital systems may help health care services pinpoint areas in need of improvement and organizational change. Without this, digital systems used for RTF may not be successful, and patients’ voices may go unheard.</p>
        <p>Therefore, this systematic review aims to evaluate the digital maturity of digital RTF systems. Specific objectives were to (1) describe the digital modes utilized; (2) provide insights into patients’ and staff views of these digital systems; and (3) demonstrate digital maturity by systematically scoring individual digital systems.</p>
      </sec>
    </sec>
    <sec sec-type="methods">
      <title>Methods</title>
      <sec>
        <title>Search Strategy</title>
        <p>The following databases were searched: Medical Literature Analysis and Retrieval System Online, EMBASE, PsycINFO, The Cochrane Library (Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled Trials, Cochrane Methodology Register), Global Health, Health Management Information Consortium, CINAHL, and Web of Science. In addition, gray literature and Google Scholar were utilized to extract papers that were not retrieved in the databases searched. Publications from January 2000 to February 2017 were included. We limited our electronic searches to studies on or after 2000 because it was around this time when the digital technology revolution in health care began to emerge [<xref ref-type="bibr" rid="ref19">19</xref>]. Owing to the diversity of terms used inferring patient experience, combinations of search terms were used. <xref ref-type="app" rid="app1">Multimedia Appendix 1</xref> provides the complete list of subheadings (Medical Subject Headings) and keywords.</p>
      </sec>
      <sec>
        <title>Inclusion Criteria</title>
        <p>Studies were deemed eligible for inclusion if (1) digital modes of administration were employed; (2) collection was in real time (at the point of care) or near real time (immediately after discharge); and (3) they were conducted in a primary or secondary care setting. There was no restriction on the age of the patient population of interest. Both quantitative and qualitative studies were included. <xref ref-type="app" rid="app1">Multimedia Appendix 1</xref> provides further details of the inclusion criteria.</p>
      </sec>
      <sec>
        <title>Search Flow</title>
        <p>The research adhered to the guideline presented in the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2009 checklist [<xref ref-type="bibr" rid="ref20">20</xref>]. Data analysis involved the comparison of included studies and extracted data. Due to the heterogeneous nature of the studies, a narrative synthesis was deemed most appropriate. This was followed by scoring the digital systems reported in the studies to determine the digital maturity.</p>
      </sec>
      <sec>
        <title>Digital Maturity</title>
        <p>An existing framework [<xref ref-type="bibr" rid="ref17">17</xref>] was utilized to determine the digital maturity of individual digital systems. This framework is embedded in the literature and has the benefit of systematically assessing the effectiveness of any digital system in health care. Each included study was scored across four key domains—capacity or resource, usage, interoperability, and impact. The framework highlights key questions for each domain and is based on “yes” or “no” response to each question. We assigned a maximum of 1 point if the digital system in each study demonstrated appropriate evidence for that particular domain. The maximum overall points a study could achieve was 4. This indicates the overall success of the digital platform [<xref ref-type="bibr" rid="ref17">17</xref>]. Two reviewers (MK and KF) independently scored each study; disagreements in scoring were resolved by discussion between the two reviewers. Interrater agreement <italic>kappa</italic> was calculated.</p>
      </sec>
    </sec>
    <sec sec-type="results">
      <title>Results</title>
      <sec>
        <title>Overall Description</title>
        <p>The initial search returned 3456 papers; after removing duplicates, 3438 papers were retained. The titles and abstracts were screened, and 112 papers were identified as potentially eligible for inclusion. Full-text papers were retrieved and assessed for inclusion, of which 13 were retained for final inclusion. RTF was defined as feedback collected while patients are in a hospital, at the point of care, while receiving care, or immediately after discharge. The main reason for exclusion was the papers did not report patient experiences or reported user experience of other digital technology. <xref ref-type="fig" rid="figure1">Figure 1</xref> illustrates the PRISMA flowchart representing the study selection process and reasons for exclusion.</p>
        <p>The reasons for exclusion of records (n=3326) and full-text papers (n=99) were the following: nondigital mode of administration (n=241), not real time or near real time (n=130), assessment or evaluation of other parameters (n=1489), feasibility or usability testing of digital systems not related to patient experience data collection (n=655), experience of other digital technology (n=848), and reviews (n=62).</p>
       
      </sec>
      <sec>
        <title>Systematic Review of Studies</title>
        <sec>
          <title>Study Characteristics</title>
          <p>Of the 13 studies included in the final review (<xref ref-type="table" rid="table1">Table 1</xref>), 5 were based in general practice [<xref ref-type="bibr" rid="ref10">10</xref>,<xref ref-type="bibr" rid="ref21">21</xref>-<xref ref-type="bibr" rid="ref24">24</xref>] and the rest were based in an acute care hospital setting [<xref ref-type="bibr" rid="ref9">9</xref>,<xref ref-type="bibr" rid="ref25">25</xref>-<xref ref-type="bibr" rid="ref31">31</xref>]. Of all the studies, 5 were from the United Kingdom [<xref ref-type="bibr" rid="ref21">21</xref>,<xref ref-type="bibr" rid="ref22">22</xref>,<xref ref-type="bibr" rid="ref24">24</xref>,<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref28">28</xref>], 7 from the United States [<xref ref-type="bibr" rid="ref9">9</xref>,<xref ref-type="bibr" rid="ref10">10</xref>,<xref ref-type="bibr" rid="ref26">26</xref>,<xref ref-type="bibr" rid="ref27">27</xref>,<xref ref-type="bibr" rid="ref29">29</xref>-<xref ref-type="bibr" rid="ref31">31</xref>], and 1 from Canada [<xref ref-type="bibr" rid="ref23">23</xref>]. All but one [<xref ref-type="bibr" rid="ref28">28</xref>] studies were based on adult populations. However, the experience was reported by adults (parents or relatives) for the study [<xref ref-type="bibr" rid="ref28">28</xref>] conducted in the neonatal ward. Five studies were qualitative studies on patients’ or staff views [<xref ref-type="bibr" rid="ref21">21</xref>,<xref ref-type="bibr" rid="ref24">24</xref>] and on barriers to and facilitators [<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref27">27</xref>,<xref ref-type="bibr" rid="ref28">28</xref>] of RTF. The remainder of the studies used a quantitative approach with varied outcome measures, of which the recurring measures were response rates of RTF [<xref ref-type="bibr" rid="ref9">9</xref>,<xref ref-type="bibr" rid="ref10">10</xref>,<xref ref-type="bibr" rid="ref22">22</xref>,<xref ref-type="bibr" rid="ref23">23</xref>,<xref ref-type="bibr" rid="ref27">27</xref>,<xref ref-type="bibr" rid="ref29">29</xref>] and association with patient demographics, that is, age, gender, ethnicity, and literacy [<xref ref-type="bibr" rid="ref9">9</xref>,<xref ref-type="bibr" rid="ref22">22</xref>,<xref ref-type="bibr" rid="ref23">23</xref>,<xref ref-type="bibr" rid="ref31">31</xref>].</p>
           <fig id="figure1" position="float">
          <label>Figure 1</label>
          <caption>
            <p>The Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2009 checklist.</p>
          </caption>
          <graphic xlink:href="jmir_v21i1e9076_fig1.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
        </fig>
          <table-wrap position="float" id="table1">
            <label>Table 1</label>
            <caption>
              <p>Study characteristics of the 13 studies included in the systematic review.</p>
            </caption>
            <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
              <col width="270"/>
              <col width="150"/>
              <col width="130"/>
              <col width="270"/>
              <col width="180"/>
              <thead>
                <tr valign="top">
                  <td>Publication title; author(s), year</td>
                  <td>Study design</td>
                  <td>Duration of study</td>
                  <td>Types of survey questionnaire(s)</td>
                  <td>Mode of administration</td>
                </tr>
              </thead>
              <tbody>
                <tr valign="top">
                  <td>Capturing patient experience: a qualitative study implementing real-time feedback in primary care; Carter M et al, 2016 [<xref ref-type="bibr" rid="ref21">21</xref>]</td>
                  <td>Qualitative</td>
                  <td>3 months</td>
                  <td>Modified<break/>Staff opinions (semistructured interviews and focus groups) using Normalization Process Theory</td>
                  <td>Kiosks</td>
                </tr>
                <tr valign="top">
                  <td>Patients’ use and views of real-time feedback technology in general practice; Wright C et al, 2017</td>
                  <td>Exploratory randomized trial</td>
                  <td>3 months</td>
                  <td>Modified (amalgamated Friends and Family Test, 6 items focusing on access, communication and satisfaction [derived from general practitioner patient survey], 2 practices tailored questions<sup>a</sup>)</td>
                  <td>2 touch screens (1 Kiosk and 1 desktop device)</td>
                </tr>
                <tr valign="top">
                  <td>Measuring the patient experience in primary care. Comparing e-mail and waiting room survey delivery in a family health team; Slater M et al, 2016 [<xref ref-type="bibr" rid="ref23">23</xref>]</td>
                  <td>Cross-sectional comparative analysis</td>
                  <td>1 month</td>
                  <td>Modified (amalgamated Commonwealth Fund International Health Policy Survey, patient demographics, self-rated health)</td>
                  <td>Tablet</td>
                </tr>
                <tr valign="top">
                  <td>Barriers and facilitators of a near real-time feedback approach for measuring patient experiences of hospital care; Kasbauer et al, 2017 [<xref ref-type="bibr" rid="ref25">25</xref>]</td>
                  <td>Qualitative</td>
                  <td>10 months</td>
                  <td>Novel and validated (Compassionate Care Toolkit)</td>
                  <td>Tablet and kiosks</td>
                </tr>
                <tr valign="top">
                  <td>Real-time patient survey data during routine clinical activities for rapid-cycle quality improvement; Wofford et al, 2015 [<xref ref-type="bibr" rid="ref10">10</xref>]</td>
                  <td>Feasibility study</td>
                  <td>1 month</td>
                  <td>Modified (dental care, waiting room experience, continuity, and internet access)</td>
                  <td>Tablet</td>
                </tr>
                <tr valign="top">
                  <td>Real-time patient experience surveys of hospitalized medical patients; Indovina et al, 2016 [<xref ref-type="bibr" rid="ref26">26</xref>]</td>
                  <td>Prospective randomized</td>
                  <td>5 months</td>
                  <td>Previously validated (US Department of Health and Human Service and the Hospital Consumer Assessment of Healthcare Providers and Systems [HCAHPS])</td>
                  <td>Web-based platform</td>
                </tr>
                <tr valign="top">
                  <td>Evaluating patient-centred care (PCC): pilot study testing feasibility of electronic data collection in hospitalised older adults; Duffy et al, 2012 [<xref ref-type="bibr" rid="ref27">27</xref>]</td>
                  <td>Cross-sectional feasibility</td>
                  <td>3 months</td>
                  <td>Previously validated (e-Caring Assessment Tool)</td>
                  <td>Tablet</td>
                </tr>
                <tr valign="top">
                  <td>Patient experience tracker (PET) survey as measure of quality in the neonatal unit; Aladangady et al, 2011 [<xref ref-type="bibr" rid="ref28">28</xref>]</td>
                  <td>Qualitative</td>
                  <td>N/A<sup>b</sup></td>
                  <td>Novel</td>
                  <td>Tablet</td>
                </tr>
                <tr valign="top">
                  <td>Development and validation of the tool to assess inpatient satisfaction with care from hospitalists; Torok et al, 2014 [<xref ref-type="bibr" rid="ref29">29</xref>]</td>
                  <td>Cross-sectional</td>
                  <td>3 months</td>
                  <td>Novel and validated (Tool to Assess Inpatient Satisfaction with Care from Hospitalists)</td>
                  <td>Tablet<break/>Paper</td>
                </tr>
                <tr valign="top">
                  <td>Incentivized digital outcomes collection; Isenberg S et al, 2001 [<xref ref-type="bibr" rid="ref30">30</xref>]</td>
                  <td>Feasibility study</td>
                  <td>3 months</td>
                  <td>Previously validated (Visit Rating Questionnaire)</td>
                  <td>Telephone (electronic voice response technology)</td>
                </tr>
                <tr valign="top">
                  <td>Exploring patients’ views toward giving Web-based feedback and rating to general practitioners in England: a qualitative descriptive study; Patel et al, 2016 [<xref ref-type="bibr" rid="ref24">24</xref>]</td>
                  <td>Descriptive exploratory qualitative approach</td>
                  <td>N/A</td>
                  <td>Previously validated (Friends and Family Test)</td>
                  <td>Web-based platform (National Health Service Choices)<break/>Paper</td>
                </tr>
                <tr valign="top">
                  <td>Obtaining patient feedback at point of service using electronic kiosks; Dirocco et al, 2011 [<xref ref-type="bibr" rid="ref9">9</xref>]</td>
                  <td>Feasibility study</td>
                  <td>1.5 months</td>
                  <td>Modified (National Committee for Quality Assurance’s Healthcare Effectiveness Data and Information Set and Quality Measurement standards)</td>
                  <td>Kiosk</td>
                </tr>
                <tr valign="top">
                  <td>Improving patient satisfaction through physician education, feedback, and incentives; Banka et al, 2015 [<xref ref-type="bibr" rid="ref31">31</xref>]</td>
                  <td>Nonrandomized comparative study</td>
                  <td>14 months (7 months each year)</td>
                  <td>Previously validated (Assessing Residents’ Connect with patients, Introduce yourself and role, Communicate, Ask and anticipate, Respond, and Exit courteously and HCAHPS)</td>
                  <td>Paper and Web-based platform (results sent via email)</td>
                </tr>
              </tbody>
            </table>
            <table-wrap-foot>
              <fn id="table1fn1">
                <p><sup>a</sup>Filter questions (tailored to patients visit).</p>
              </fn>
              <fn id="table1fn2">
                <p><sup>b</sup>N/A: not applicable.</p>
              </fn>
            </table-wrap-foot>
          </table-wrap>
        </sec>
        <sec>
          <title>Modes of Feedback</title>
          <p>RTF was collected using touchscreens (kiosk) [<xref ref-type="bibr" rid="ref9">9</xref>,<xref ref-type="bibr" rid="ref21">21</xref>,<xref ref-type="bibr" rid="ref22">22</xref>,<xref ref-type="bibr" rid="ref25">25</xref>], tablets [<xref ref-type="bibr" rid="ref10">10</xref>,<xref ref-type="bibr" rid="ref23">23</xref>,<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref27">27</xref>-<xref ref-type="bibr" rid="ref29">29</xref>], and Web-based platform [<xref ref-type="bibr" rid="ref24">24</xref>,<xref ref-type="bibr" rid="ref26">26</xref>,<xref ref-type="bibr" rid="ref30">30</xref>,<xref ref-type="bibr" rid="ref31">31</xref>] in the included studies. With regards to the timing of feedback, 11 studies collected their feedback in real time [<xref ref-type="bibr" rid="ref9">9</xref>,<xref ref-type="bibr" rid="ref10">10</xref>,<xref ref-type="bibr" rid="ref21">21</xref>-<xref ref-type="bibr" rid="ref23">23</xref>,<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref27">27</xref>-<xref ref-type="bibr" rid="ref31">31</xref>] and 2 studies in near real time [<xref ref-type="bibr" rid="ref24">24</xref>,<xref ref-type="bibr" rid="ref30">30</xref>] (ie, within 48 hours of discharge). Patient experience questionnaires used in each study varied; 5 studies modified an existing questionnaire [<xref ref-type="bibr" rid="ref9">9</xref>,<xref ref-type="bibr" rid="ref10">10</xref>,<xref ref-type="bibr" rid="ref21">21</xref>-<xref ref-type="bibr" rid="ref23">23</xref>], 5 used previously validated questionnaires [<xref ref-type="bibr" rid="ref24">24</xref>,<xref ref-type="bibr" rid="ref26">26</xref>,<xref ref-type="bibr" rid="ref27">27</xref>,<xref ref-type="bibr" rid="ref30">30</xref>,<xref ref-type="bibr" rid="ref31">31</xref>], 2 used novel and validated questionnaires [<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref29">29</xref>], and 1 used a novel and nonvalidated questionnaire [<xref ref-type="bibr" rid="ref28">28</xref>]. The majority of the questionnaires were in English only.</p>
        </sec>
        <sec>
          <title>Response Rates of Real-Time Feedback</title>
          <p>Of the 13 studies, 6 studies [<xref ref-type="bibr" rid="ref9">9</xref>,<xref ref-type="bibr" rid="ref10">10</xref>,<xref ref-type="bibr" rid="ref22">22</xref>,<xref ref-type="bibr" rid="ref23">23</xref>,<xref ref-type="bibr" rid="ref27">27</xref>,<xref ref-type="bibr" rid="ref29">29</xref>] evaluated response rates (percentage) as part of their outcome measures. The response rates were 55.9% [<xref ref-type="bibr" rid="ref23">23</xref>], 43.4% [<xref ref-type="bibr" rid="ref10">10</xref>], and 2.5% [<xref ref-type="bibr" rid="ref22">22</xref>] for studies conducted in primary care and 54.9% [<xref ref-type="bibr" rid="ref9">9</xref>], 59.2% [<xref ref-type="bibr" rid="ref27">27</xref>], and 61.5% [<xref ref-type="bibr" rid="ref29">29</xref>] for those conducted in secondary care. <xref ref-type="app" rid="app2">Multimedia Appendix 2</xref> demonstrates the absolute numbers of responses in each study identified above. Only 1 study evaluated response rates of RTF compared with non-RTF and showed that RTF improved response rates (55.9% vs 19.8%) [<xref ref-type="bibr" rid="ref23">23</xref>].</p>
        </sec>
        <sec>
          <title>Completion Time</title>
          <p>Of all studies, 4 evaluated time to completion, and this varied from 40.4 seconds [<xref ref-type="bibr" rid="ref10">10</xref>], &lt;2 minutes [<xref ref-type="bibr" rid="ref22">22</xref>], 3 minutes [<xref ref-type="bibr" rid="ref9">9</xref>] to 31 minutes [<xref ref-type="bibr" rid="ref27">27</xref>]. However, each questionnaire was different as it varied in length and number of questions.</p>
        </sec>
        <sec>
          <title>Patient Demographics According to Real-Time Feedback Responses</title>
          <p>The patient demographics that were collected varied, and 7 [<xref ref-type="bibr" rid="ref9">9</xref>,<xref ref-type="bibr" rid="ref22">22</xref>,<xref ref-type="bibr" rid="ref23">23</xref>,<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref27">27</xref>,<xref ref-type="bibr" rid="ref29">29</xref>,<xref ref-type="bibr" rid="ref31">31</xref>] of the 13 studies evaluated responses by patient demographics. Only Slater et al [<xref ref-type="bibr" rid="ref23">23</xref>] compared RTF and non-RTF responses by patient demographics; RTF showed a higher percentage response in males (43.5 vs 36.6), in age (years) bracket 18-24 and 24-34 (6.7 vs 3.6 and 23.8 vs 18.5, respectively), and in those with lower literacy (34.4 vs 21.3) compared with non-RTF. Banka et al [<xref ref-type="bibr" rid="ref31">31</xref>] revealed a higher percentage of male respondents (55.3 vs 41.4) with a white predominance (62.5 vs 60.9) using RTF compared with non-RTF. However, Wright et al [<xref ref-type="bibr" rid="ref22">22</xref>] revealed different findings. There was a higher percentage response in females in the 46-65 (26.2%) and &gt;65 (33.8%) age range and higher response from white than from ethnic patients. Dirocco et al [<xref ref-type="bibr" rid="ref9">9</xref>] showed mixed results in that although the response was higher from females, there was a higher percentage response from African American individuals than from white American individuals (48.5 vs 38.6) and those aged 18-49 years (45.2). Torok et al [<xref ref-type="bibr" rid="ref29">29</xref>] and Duffy et al [<xref ref-type="bibr" rid="ref27">27</xref>] showed that the response rates from elderly patients were adequate; however, of these elderly patients, there was an overrepresentation in females [<xref ref-type="bibr" rid="ref27">27</xref>,<xref ref-type="bibr" rid="ref29">29</xref>], white individuals [<xref ref-type="bibr" rid="ref27">27</xref>,<xref ref-type="bibr" rid="ref29">29</xref>], and educated patients [<xref ref-type="bibr" rid="ref27">27</xref>] who were aged ≥60 years. Kasbauer et al [<xref ref-type="bibr" rid="ref25">25</xref>] showed that elderly patients responded to the survey but with the help of volunteers. <xref ref-type="app" rid="app3">Multimedia Appendix 3</xref> summarizes the findings from the included studies.</p>
        </sec>
        <sec>
          <title>Patient Views of Real-Time Feedback</title>
          <p>Patients’ views of RTF were collected in 6 studies [<xref ref-type="bibr" rid="ref9">9</xref>,<xref ref-type="bibr" rid="ref10">10</xref>,<xref ref-type="bibr" rid="ref22">22</xref>,<xref ref-type="bibr" rid="ref24">24</xref>,<xref ref-type="bibr" rid="ref27">27</xref>,<xref ref-type="bibr" rid="ref30">30</xref>]. The main pros of RTF were as follows: easy to complete [<xref ref-type="bibr" rid="ref10">10</xref>,<xref ref-type="bibr" rid="ref22">22</xref>], easy to use [<xref ref-type="bibr" rid="ref9">9</xref>,<xref ref-type="bibr" rid="ref27">27</xref>], and willingness to use [<xref ref-type="bibr" rid="ref24">24</xref>,<xref ref-type="bibr" rid="ref27">27</xref>] the data collection tool. Isenberg et al [<xref ref-type="bibr" rid="ref30">30</xref>] showed that patients were motivated to use RTF; however, this was incentivized with the reward of free long-distance minutes for patients and with a practice improvement program for the staff. Patel et al [<xref ref-type="bibr" rid="ref24">24</xref>] identified that younger patients (aged &lt;50 years) found digital platforms more accessible compared with older ones (aged ≥60 years). However, Duffy et al [<xref ref-type="bibr" rid="ref27">27</xref>] further evaluated opinions of older adults and found a preference toward digital platforms; for example, 70% of patients preferred to answer questions using an iPad. Four studies found that patients thought RTF completion was quick with fast turnaround time [<xref ref-type="bibr" rid="ref9">9</xref>,<xref ref-type="bibr" rid="ref10">10</xref>,<xref ref-type="bibr" rid="ref22">22</xref>,<xref ref-type="bibr" rid="ref27">27</xref>]. The main cons of RTF were as follows: lack of awareness of the opportunity to leave feedback [<xref ref-type="bibr" rid="ref22">22</xref>,<xref ref-type="bibr" rid="ref24">24</xref>], lack of time [<xref ref-type="bibr" rid="ref22">22</xref>], concerns over technology [<xref ref-type="bibr" rid="ref22">22</xref>,<xref ref-type="bibr" rid="ref24">24</xref>], concerns over anonymity [<xref ref-type="bibr" rid="ref22">22</xref>,<xref ref-type="bibr" rid="ref24">24</xref>], and age- or disease-related exclusion [<xref ref-type="bibr" rid="ref24">24</xref>,<xref ref-type="bibr" rid="ref27">27</xref>]. Interestingly, Wright et al [<xref ref-type="bibr" rid="ref22">22</xref>] showed that those who did not use RTF were still positive about the idea of providing RTF.</p>
        </sec>
        <sec>
          <title>Staff Views of Real-Time Feedback</title>
          <p>Staff views were collected in 4 studies [<xref ref-type="bibr" rid="ref9">9</xref>,<xref ref-type="bibr" rid="ref21">21</xref>,<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref28">28</xref>]. Positive staff views toward RTF were as follows: immediacy of RTF compared with traditional surveys, which helped offset “feedback fatigue,” complemented other forms of feedback with the potential of integrating with other data sources [<xref ref-type="bibr" rid="ref21">21</xref>]. Staff found the RTF data was felt to be useful when summarized, highlighting areas of improvement at-a-glance on a dashboard [<xref ref-type="bibr" rid="ref25">25</xref>], and when there was coworking with senior clinical staff [<xref ref-type="bibr" rid="ref25">25</xref>], increasing staff morale and awareness of RTF. In some studies, free text was found to be more useful than quantitative questions [<xref ref-type="bibr" rid="ref21">21</xref>,<xref ref-type="bibr" rid="ref25">25</xref>] as it brought the experiences to life for frontline staff and added a “sense of urgency” to address them in improvement efforts [<xref ref-type="bibr" rid="ref25">25</xref>]. Concerns included duplication with other forms of feedback, lack of time for patients to reflect on experience, extreme views, exclusion of certain patient groups, staff did not feel included in decision making [<xref ref-type="bibr" rid="ref21">21</xref>], initial reluctance [<xref ref-type="bibr" rid="ref28">28</xref>], limited time to review, and lack of access to the results [<xref ref-type="bibr" rid="ref25">25</xref>].</p>
        </sec>
        <sec>
          <title>Evaluating Digital Maturity of Real-Time Feedback Systems</title>
          <p>Three studies received a score of 3 [<xref ref-type="bibr" rid="ref10">10</xref>,<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref30">30</xref>], 2 [<xref ref-type="bibr" rid="ref9">9</xref>,<xref ref-type="bibr" rid="ref21">21</xref>,<xref ref-type="bibr" rid="ref22">22</xref>], or 1 [<xref ref-type="bibr" rid="ref27">27</xref>,<xref ref-type="bibr" rid="ref28">28</xref>,<xref ref-type="bibr" rid="ref31">31</xref>] points, respectively, while 4 studies [<xref ref-type="bibr" rid="ref23">23</xref>,<xref ref-type="bibr" rid="ref24">24</xref>,<xref ref-type="bibr" rid="ref26">26</xref>,<xref ref-type="bibr" rid="ref29">29</xref>] were attributed 0 points. While 7 studies demonstrated capacity or resource, 8 demonstrated impact. None of the studies demonstrated digital systems that were deemed to be mature, that is, did not achieve a full score in all of the 4 domains. We describe in detail how the digital system in each study demonstrated evidence that determined whether a point was given in each of the 4 domains. Following independent scoring by MK and KF, Cohen <italic>kappa</italic> was calculated as 0.98, suggesting an almost perfect agreement. There was only one domain where the scoring differed (Usage) [<xref ref-type="bibr" rid="ref26">26</xref>], and through discussion, a final score of 0 was inputted. <xref ref-type="app" rid="app4">Multimedia Appendix 4</xref> details the individual scoring with a description on each domain.</p>
        </sec>
      </sec>
    </sec>
    <sec sec-type="discussion">
      <title>Discussion</title>
      <sec>
        <title>Principal Findings</title>
        <p>This review highlights that digital modes of administration of RTF are well accepted by patients and staff, with response rates equivalent to, and in some studies better than, non-RTF. From a patient’s perspective, it has been reported that its influx alongside demographic shifts such as increasing aging population and ethnicity [<xref ref-type="bibr" rid="ref32">32</xref>,<xref ref-type="bibr" rid="ref33">33</xref>] can lead to patient disengagement and poor uptake of these technologies [<xref ref-type="bibr" rid="ref34">34</xref>]. On the contrary, we have shown that patients are in fact willing to engage with this technology for experience reporting, thereby disrupting previous nonreal-time, paper-based feedback. However, digital technology may not be preferred by all patients; therefore, health care organizations need to be mindful and consider other means of inclusivity when developing digital health care systems. From a staff perspective, although RTF is well received, problems arising from the lack of robust digital infrastructure [<xref ref-type="bibr" rid="ref25">25</xref>] can thwart improvement efforts. From a health care organizational perspective, most digital systems were unable to demonstrate interoperability and very few demonstrated impact and, therefore, were not deemed digitally mature, compromising success within the organization.</p>
      </sec>
      <sec>
        <title>Digital Maturity of Existing Real-Time Feedback</title>
        <p>By nature, maturity frameworks not only identify components of a successful system but also capture the evolution of a digital system from conception to implementation to impact. Using evidence where possible from the included studies, we highlight how each of the 4 domains contribute to ensuring digital maturity.</p>
      </sec>
      <sec>
        <title>Capacity or Resource</title>
        <p>The success of digital health is contingent on establishing the necessary capacity and resources to build, use, and support access to high-quality health services and harvest useful information in the health system. There was a general lack of analytical support in most digital systems to extract valuable information such as the ability to examine user-specific interaction [<xref ref-type="bibr" rid="ref10">10</xref>] or adjust survey responses [<xref ref-type="bibr" rid="ref23">23</xref>]. A Kings’ Fund report explains that gleaning information from experience data requires the same analytical capability as interpreting clinical data; however, this is often unavailable [<xref ref-type="bibr" rid="ref35">35</xref>]. The resource capacity requirements stretch beyond health professionals and technology specialists across the continuum of care to include health information managers to information security professionals [<xref ref-type="bibr" rid="ref36">36</xref>]. Staff time was an important barrier in data collection, and this is in keeping with other studies that reported a lack of time or resources to collect, analyze, or act on data and need for staff training in data analysis and statistics to facilitate full understanding and use of results [<xref ref-type="bibr" rid="ref37">37</xref>-<xref ref-type="bibr" rid="ref39">39</xref>]. To circumvent this, some of the studies used volunteers [<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref31">31</xref>] and incentives [<xref ref-type="bibr" rid="ref30">30</xref>,<xref ref-type="bibr" rid="ref31">31</xref>] to gather data. This generates concerns such as response bias and competition among clinicians, and there may be an element of the Hawthorne effect, whereby clinicians modify their behavior as they are being observed, which may explain the positive outcomes in those studies. Going forward, a strategic approach should take into consideration building human and institutional capacity, nurturing clinical and community champions, and developing the base of knowledgeable users to drive appropriate adoption of digital systems [<xref ref-type="bibr" rid="ref36">36</xref>].</p>
      </sec>
      <sec>
        <title>Usage</title>
        <p>As the needs and experiences differ greatly across these groups, a flexible or responsive data collection mode is needed, which can aid patients during the data collection process. While most patients in the included studies were comfortable using the digital system and required little prompting or help once they engaged with the survey, some differences were noted. Concerns exist that older patients are less comfortable with technology [<xref ref-type="bibr" rid="ref40">40</xref>]; however, there was an overrepresentation in responses from patients aged &gt;65 years in the included studies [<xref ref-type="bibr" rid="ref22">22</xref>,<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref27">27</xref>,<xref ref-type="bibr" rid="ref29">29</xref>,<xref ref-type="bibr" rid="ref31">31</xref>]. Moreover, some of these studies were conducted in the elderly population [<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref27">27</xref>]. Despite this, the response rate in this patient group was adequate, suggesting that their movement into digital life is evolving. Furthermore, when certain conditions are met such as providing a supportive, nonhurried environment [<xref ref-type="bibr" rid="ref41">41</xref>]; bold, plain, and large font with fewer graphics; and avoidance of certain colors [<xref ref-type="bibr" rid="ref42">42</xref>], older adults can be successful users. The use of videos in the software can enhance accuracy and acceptability [<xref ref-type="bibr" rid="ref10">10</xref>]. Furthermore, trained volunteers can provide a responsive approach to real-time data collection from lesser heard groups [<xref ref-type="bibr" rid="ref14">14</xref>], increasing patient engagement and, subsequently, improving response rates. In addition, they can help reduce the data collection burden, which may otherwise fall on clinical staff and may even account for the false positives as seen in some surveys [<xref ref-type="bibr" rid="ref43">43</xref>] due to the presence of staff during survey completion.</p>
        <p>If data collection is obtrusive, unrealistic, or inaccurate, it can undermine enthusiasm for assessing and improving practice quality [<xref ref-type="bibr" rid="ref44">44</xref>,<xref ref-type="bibr" rid="ref45">45</xref>]. However, the digital systems in this review demonstrated quick turnaround of data collection, collation, and dissemination of results. This was key to successful implementation of digital systems as it promoted “buy-in” from staff. Furthermore, patients are fatigued of requests for feedback in health care and in daily life; hence, data collection should be quick, focused, and part of routine care to encourage participation from patients and clinicians and to be sustainable in a busy setting [<xref ref-type="bibr" rid="ref10">10</xref>].</p>
      </sec>
      <sec>
        <title>Interoperability</title>
        <p>From a health care perspective, interoperability is needed to reform the chaotic, and, at times, dysfunctional nature of how information is shared within and among health care services. There was a ubiquitous shortfall in achieving interoperability among the digital systems in this review. Data that are not interoperable cannot be analyzed alongside other data indicative of care quality. This perpetuates the siloed approach to data interpretation and creates a chasm between data and information for improvement. Some of the challenges in achieving interoperability include resistance from some vendors, prohibitively high data exchange fees, and lack of incentives to develop interoperability and technical variations. Without tackling the interoperability of RTF systems, it is likely that health care organizations will fail on delivering impactful quality improvement. This must now be a major focus for health care services, but it should be done in an organized way that prioritizes interoperability so that patient feedback data can communicate seamlessly to generate information that will benefit health care services and patients alike.</p>
      </sec>
      <sec>
        <title>Impact</title>
        <p>To genuinely demonstrate impact, the digital system should not only be able to generate quality improvement activities but also demonstrate sustainability and cost-effectiveness. Three studies [<xref ref-type="bibr" rid="ref10">10</xref>,<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref30">30</xref>] achieved a score for impact as they demonstrated a change in practice following the implementation of RTF. However, the majority of the digital systems were not able to demonstrate any impact. The duration of studies in this review was short (between 1 and 12 months), and the sustainability of the digital system to continue to deliver quality improvement could not be evaluated. Without considerations of sustainability, digital programs are of limited value.</p>
      </sec>
      <sec>
        <title>Limitations</title>
        <p>Due to publication bias, there may be unpublished evidence of nonsignificant or negative findings or findings held locally, which are not published or otherwise publicly available. We ascribed a level of digital maturity of individual systems based on the evidence provided in the studies. If this was not discernible while reviewing the studies, we assumed it to be lacking. As the remit of the included papers differed greatly, their digital systems may, in fact, have existing procedures for ensuring capacity, usage, interoperability, and impact, but the authors did not specify this information in the published paper. Of note, the studies were not evaluated for research quality before being included in the synthesis owing to the limited number of studies that were identified after exclusion.</p>
      </sec>
      <sec>
        <title>Conclusions</title>
        <p>There was not a large body of published literature on digital modes in relation to RTF. However, the evidence provided by the studies in this review demonstrates that there is a potential in using digital modes of administration of RTF as an agent for improving service delivery. Patients and staff alike are willing to engage in RTF, demonstrated by acceptable response rates. However, for RTF to be impactful, health care organizations must ensure that they have strategies in place to deliver across all levels of digital maturity. Health care services have the capacity to introduce digital solutions for RTF; however, lack of interoperability is slowing down progress. In addition, it is possible that some health care services may be wasting effort and resources when they invest in digital technologies for RTF. On balance, the direction of the health care ecosystem toward embracing digital technology looks promising, and as health care shifts toward a patient-centered model, digital technology will be an important partner in this transformation.</p>
      </sec>
    </sec>
  </body>
  <back>
    <app-group>
      <app id="app1">
        <title>Multimedia Appendix 1</title>
        <p>Subheadings (MESH) and Keywords.</p>
        <media xlink:href="jmir_v21i1e9076_app1.pdf" xlink:title="PDF File (Adobe PDF File), 35KB"/>
      </app>
      <app id="app2">
        <title>Multimedia Appendix 2</title>
        <p>This demonstrates the percentage response rates for RTF completion including absolute number of patients in each study.</p>
        <media xlink:href="jmir_v21i1e9076_app2.pdf" xlink:title="PDF File (Adobe PDF File), 16KB"/>
      </app>
      <app id="app3">
        <title>Multimedia Appendix 3</title>
        <p>Response rate in percentage and representation of responses according to patients’ demographics documented from the studies in the systematic review.</p>
        <media xlink:href="jmir_v21i1e9076_app3.pdf" xlink:title="PDF File (Adobe PDF File), 50KB"/>
      </app>
      <app id="app4">
        <title>Multimedia Appendix 4</title>
        <p>Individual scores in relation to the digital maturity framework domains. A score of one indicates that the study demonstrates evidence in that particular domain, otherwise a score of zero is ascribed.</p>
        <media xlink:href="jmir_v21i1e9076_app4.pdf" xlink:title="PDF File (Adobe PDF File), 50KB"/>
      </app>
    </app-group>
    <glossary>
      <title>Abbreviations</title>
      <def-list>
        <def-item>
          <term id="abb1">NHS</term>
          <def>
            <p>National Health Service</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb2">NIHR</term>
          <def>
            <p>National Institute for Health Research</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb3">PRISMA</term>
          <def>
            <p>Preferred Reporting Items for Systematic Reviews and Meta-Analyses</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb4">RTF</term>
          <def>
            <p>real-time feedback</p>
          </def>
        </def-item>
      </def-list>
    </glossary>
    <ack>
      <p>The research was supported by the National Institute for Health Research (NIHR) Imperial Patient Safety Translational Research Centre, NIHR Imperial Biomedical Research Centre, and The Health Foundation. The views expressed are those of the authors and not necessarily those of the NHS, the NIHR, or the Department of Health.</p>
    </ack>
    <fn-group>
      <fn fn-type="con">
        <p>MK, KF, and EM contributed to the design of the study. MK and KF managed the review process. MK led on screening, data extraction, and scoring. KF assisted in data synthesis and scoring. MK drafted the manuscript, and KF, AD, and EM reviewed the manuscript.</p>
      </fn>
      <fn fn-type="conflict">
        <p>None declared.</p>
      </fn>
    </fn-group>
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