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    <front>
        <journal-meta>
            <journal-id journal-id-type="publisher-id">JMIR</journal-id>
            <journal-id journal-id-type="nlm-ta">J Med Internet Res</journal-id>
            <journal-title>Journal of Medical Internet Research</journal-title>
            <issn pub-type="epub">1438-8871</issn>
            <publisher>
                <publisher-name>Gunther Eysenbach</publisher-name>
                <publisher-loc>JMIR Publications Inc., Toronto, Canada</publisher-loc>
            </publisher>
        </journal-meta>
        <article-meta>
            <article-id pub-id-type="publisher-id">v14i2e26</article-id>
            <article-id pub-id-type="pmid">22403770</article-id>
            <article-id pub-id-type="doi">10.2196/jmir.1968</article-id>
            <article-categories>
                <subj-group subj-group-type="article-type">
                    <subject>Original paper</subject>
                </subj-group>
            </article-categories>
            <title-group>
                <article-title>Program Completion of a Web-Based Tailored Lifestyle Intervention for Adults: Differences between a Sequential and a Simultaneous Approach</article-title>
            </title-group>
            <contrib-group>
                <contrib contrib-type="editor">
                    <name>
                        <surname>Eysenbach</surname>
                        <given-names>Gunther</given-names>
                    </name>
                </contrib>
            </contrib-group>
            <contrib-group>
                <contrib contrib-type="reviewer">
                    <name>
                        <surname>Vandelanotte</surname>
                        <given-names>Corneel</given-names>
                    </name>
                </contrib>
                <contrib contrib-type="reviewer">
                    <name>
                        <surname>Donkin</surname>
                        <given-names>Liesje</given-names>
                    </name>
                </contrib>
            </contrib-group>
            <contrib-group>
                <contrib contrib-type="author" id="contrib1" corresp="yes">
                    <name name-style="western">
                        <surname>Schulz</surname>
                        <given-names>Daniela N</given-names>
                    </name>
                    <degrees>MSc</degrees>
                    <xref ref-type="aff" rid="aff1">1</xref>
                    <address>
                        <institution>CAPHRI School for Public Health and Primary Care</institution>
                        <institution>Department of Health Promotion</institution>
                        <institution>Maastricht University</institution>
                        <addr-line>P.O. Box 616</addr-line>
                        <addr-line>Maastricht, 6200 MD</addr-line>
                        <country>Netherlands</country>
                        <phone>31 43 3882832</phone>
                        <fax>31 43 3671032</fax>
                        <email>dn.schulz@maastrichtuniversity.nl</email>
                    </address>
                </contrib>
                <contrib contrib-type="author" id="contrib2">
                    <name name-style="western">
                        <surname>Schneider</surname>
                        <given-names>Francine</given-names>
                    </name>
                    <degrees>MSc</degrees>
                    <xref ref-type="aff" rid="aff1">1</xref>
                </contrib>
                <contrib contrib-type="author" id="contrib3">
                    <name name-style="western">
                        <surname>de Vries</surname>
                        <given-names>Hein</given-names>
                    </name>
                    <degrees>PhD</degrees>
                    <xref ref-type="aff" rid="aff1">1</xref>
                </contrib>
                <contrib contrib-type="author" id="contrib4">
                    <name name-style="western">
                        <surname>van Osch</surname>
                        <given-names>Liesbeth ADM</given-names>
                    </name>
                    <degrees>PhD</degrees>
                    <xref ref-type="aff" rid="aff1">1</xref>
                </contrib>
                <contrib contrib-type="author" id="contrib5">
                    <name name-style="western">
                        <surname>van Nierop</surname>
                        <given-names>Peter WM</given-names>
                    </name>
                    <degrees>MSc</degrees>
                    <xref ref-type="aff" rid="aff2">2</xref>
                </contrib>
                <contrib contrib-type="author" id="contrib6">
                    <name name-style="western">
                        <surname>Kremers</surname>
                        <given-names>Stef PJ</given-names>
                    </name>
                    <degrees>PhD</degrees>
                    <xref ref-type="aff" rid="aff3">3</xref>
                </contrib>
            </contrib-group>
            <aff id="aff1" rid="aff1">
                <sup>1</sup>
                <institution>CAPHRI School for Public Health and Primary Care</institution>
                <institution>Department of Health Promotion</institution>
                <institution>Maastricht University</institution>
                <addr-line>Maastricht</addr-line>
                <country>Netherlands</country>
            </aff>
            <aff id="aff2" rid="aff2">
                <sup>2</sup>
                <institution>Municipal Health Services</institution>
                <institution>Department of Health Promotion</institution>
                <addr-line>Helmond</addr-line>
                <country>Netherlands</country>
            </aff>
            <aff id="aff3" rid="aff3">
                <sup>3</sup>
                <institution>Nutrition and Toxicology Research Institute Maastricht (NUTRIM)</institution>
                <institution>Department of Health Promotion</institution>
                <institution>Maastricht University</institution>
                <addr-line>Maastricht</addr-line>
                <country>Netherlands</country>
            </aff>
            <pub-date pub-type="collection">
                <season>Jan-Feb</season>
                <year>2012</year>
            </pub-date>
            <pub-date pub-type="epub">
                <day>08</day>
                <month>03</month>
                <year>2012</year>
            </pub-date>
            <volume>14</volume>
            <issue>2</issue>
            <elocation-id>e26</elocation-id>
            <!--history from ojs - api-xml-->
            <history>
                <date date-type="received">
                    <day>18</day>
                    <month>10</month>
                    <year>2011</year>
                </date>
                <date date-type="rev-request">
                    <day>26</day>
                    <month>10</month>
                    <year>2011</year>
                </date>
                <date date-type="rev-recd">
                    <day>09</day>
                    <month>12</month>
                    <year>2011</year>
                </date>
                <date date-type="accepted">
                    <day>06</day>
                    <month>01</month>
                    <year>2012</year>
                </date>
            </history>
            <!--(c) the authors - correct author names and publication date here if necessary. Date in form ', dd.mm.yyyy' after jmir.org-->
            <copyright-statement>&#169;Daniela N Schulz, Francine Schneider, Hein de Vries, Liesbeth ADM van Osch, Peter WM van Nierop, Stef PJ Kremers. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 08.03.2012. </copyright-statement>
            <copyright-year>2012</copyright-year>
            <license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by/2.0/">
                <p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Journal of Medical Internet Research, is properly cited. The complete bibliographic information, a link to the original publication on http://www.jmir.org/, as well as this copyright and license information must be included.</p>
            </license>
            <self-uri xlink:href="http://www.jmir.org/2012/2/e26/" xlink:type="simple" />
            <abstract>
                <sec sec-type="background">
                    <title>Background</title>
                    <p>Unhealthy lifestyle behaviors often co-occur and are related to chronic diseases. One effective method to change multiple lifestyle behaviors is web-based computer tailoring. Dropout from Internet interventions, however, is rather high, and it is challenging to retain participants in web-based tailored programs, especially programs targeting multiple behaviors. To date, it is unknown how much information people can handle in one session while taking part in a multiple behavior change intervention, which could be presented either sequentially (one behavior at a time) or simultaneously (all behaviors at once).</p>
                </sec>
                <sec sec-type="objectives">
                    <title>Objectives</title>
                    <p>The first objective was to compare dropout rates of 2 computer-tailored interventions: a sequential and a simultaneous strategy. The second objective was to assess which personal characteristics are associated with completion rates of the 2 interventions.</p>
                </sec>
                <sec sec-type="methods">
                    <title>Methods</title>
                    <p>Using an RCT design, demographics, health status, physical activity, vegetable consumption, fruit consumption, alcohol intake, and smoking were self-assessed through web-based questionnaires among 3473 adults, recruited through Regional Health Authorities in the Netherlands in the autumn of 2009. First, a health risk appraisal was offered, indicating whether respondents were meeting the 5 national health guidelines. Second, psychosocial determinants of the lifestyle behaviors were assessed and personal advice was provided, about one or more lifestyle behaviors.</p>
                </sec>
                <sec sec-type="results">
                    <title>Results</title>
                    <p>Our findings indicate a high non-completion rate for both types of intervention (71.0%; n = 2167), with more incompletes in the simultaneous intervention (77.1%; n = 1169) than in the sequential intervention (65.0%; n = 998). In both conditions, discontinuation was predicted by a lower age (sequential condition: OR = 1.04; <italic>P</italic> &#60; .001; CI = 1.02-1.05; simultaneous condition: OR = 1.04; <italic>P</italic> &#60; .001; CI = 1.02-1.05) and an unhealthy lifestyle (sequential condition: OR = 0.86; <italic>P</italic> = .01; CI = 0.76-0.97; simultaneous condition: OR = 0.49; <italic>P</italic> &#60; .001; CI = 0.42-0.58). In the sequential intervention, being male (OR = 1.27; <italic>P</italic> = .04; CI = 1.01-1.59) also predicted dropout. When respondents failed to adhere to at least 2 of the guidelines, those receiving the simultaneous intervention were more inclined to drop out than were those receiving the sequential intervention.</p>
                </sec>
                <sec sec-type="conclusion">
                    <title>Conclusion</title>
                    <p>Possible reasons for the higher dropout rate in our simultaneous intervention may be the amount of time required and information overload. Strategies to optimize program completion as well as continued use of computer-tailored interventions should be studied.</p>
                </sec>
                <sec sec-type="clinicalTrial">
                    <title>Trial Registration</title>
                    <p>Dutch Trial Register NTR2168</p>
                </sec>
            </abstract>
            <kwd-group>
                <kwd>Internet</kwd>
                <kwd>dropout</kwd>
                <kwd>computer tailoring</kwd>
                <kwd>multiple health behavior change intervention</kwd>
                <kwd>sequential</kwd>
                <kwd>simultaneous</kwd>
                <kwd>lifestyle</kwd>
            </kwd-group>
        </article-meta>
    </front>
    <body>
        <sec sec-type="introduction">
            <title>Introduction</title>
            <p>Unhealthy lifestyle behaviors, such as physical inactivity, insufficient fruit and vegetable intake, high alcohol consumption, and smoking, often co-occur [<xref ref-type="bibr" rid="ref1">1</xref>-<xref ref-type="bibr" rid="ref4">4</xref>] and are related to chronic diseases like cardiovascular diseases and cancer [<xref ref-type="bibr" rid="ref5">5</xref>]. In view of this co-occurrence, various studies have emphasized the need to develop interventions addressing more than one risk behavior.</p>
            <p>One method to change lifestyle behavior is the use of computer tailoring. Positive aspects of web-based computer-tailored programs are that these can be administered in privacy and at a time that suits the respondent [<xref ref-type="bibr" rid="ref6">6</xref>], and that they can be integrated in larger multicomponent interventions [<xref ref-type="bibr" rid="ref7">7</xref>]. In addition to their positive effects on health behavior change [e.g. 7-10], numerous studies have shown that (web-based) tailored messages attract the public&#8217;s attention [<xref ref-type="bibr" rid="ref11">11</xref>,<xref ref-type="bibr" rid="ref12">12</xref>], are perceived as personally relevant [<xref ref-type="bibr" rid="ref13">13</xref>], and are usually better read, saved, remembered, and discussed with others than non-tailored materials [<xref ref-type="bibr" rid="ref7">7</xref>,<xref ref-type="bibr" rid="ref9">9</xref>,<xref ref-type="bibr" rid="ref14">14</xref>-<xref ref-type="bibr" rid="ref16">16</xref>].</p>
            <p>The public health impact of an intervention is defined by the program&#8217;s efficacy multiplied by its reach [<xref ref-type="bibr" rid="ref7">7</xref>,<xref ref-type="bibr" rid="ref17">17</xref>]. Thus, the impact is highest when an intervention is effective and has a wide reach. In view of the high rate of Internet access these days (91% in the Netherlands) [<xref ref-type="bibr" rid="ref18">18</xref>], Internet-based programs may have the potential to reach large numbers of people. However, various studies have pointed out that the actual use of web-based interventions may be limited [<xref ref-type="bibr" rid="ref19">19</xref>-<xref ref-type="bibr" rid="ref21">21</xref>] and that leaving an Internet intervention prematurely is common [e.g. 22-24]. Brouwer et al. [<xref ref-type="bibr" rid="ref25">25</xref>] reported that more than half of the visitors (Dutch adults) of their online intervention left the website within 30 seconds, while 10.5% stayed for more than 15 minutes. Hence, there is a need to identify factors associated with early discontinuation or continuation of participation in web-based programs promoting the adoption of healthy lifestyles.</p>
            <p>Various tailoring strategies can be used to address multiple behaviors with computer-tailored interventions, such as a sequential or a simultaneous strategy. A simultaneous strategy concurrently targets multiple behaviors for intervention, while a sequential strategy targets a single behavior at a time. The few studies that have investigated the effects on behavioral change of sequential versus simultaneous strategies to provide multiple health-behavior change interventions reported inconsistent findings [<xref ref-type="bibr" rid="ref26">26</xref>-<xref ref-type="bibr" rid="ref28">28</xref>]. According to Vandelanotte et al. [<xref ref-type="bibr" rid="ref28">28</xref>], the sequential strategy may be more effective than the simultaneous strategy when participants can choose the behavior on which they would prefer to receive personal feedback first, and can start with this part of the intervention, instead of the lifestyle modules being presented in a predefined order [see also 29].</p>
            <p>In any case, behavioral change will be more likely when someone completes the whole intervention program [<xref ref-type="bibr" rid="ref30">30</xref>], as early dropout is a hazard to the effectiveness of any intervention. Hence, when considering the use of a sequential or simultaneous approach for web-based computer-tailored interventions, it is important to study continuation rates. In both types of intervention, people receive only the modules about health behavior topics for which they are at risk in order to increase the relevance of the intervention [<xref ref-type="bibr" rid="ref31">31</xref>]. When being at risk for at least two behaviors, people in the simultaneous intervention receive, and thus have to handle, more information at one point in time compared to a sequential intervention, in which the same amount of information is spread over time. Therefore, a simultaneous strategy, including a more complex program, is likely to require more time from the respondents and to increase the behavior change demands [<xref ref-type="bibr" rid="ref31">31</xref>], especially when respondents fail to meet multiple guidelines. Hence, because a simultaneous approach may lead to an overload of information, such a strategy may potentially lead to higher dropout rates than a sequential strategy [<xref ref-type="bibr" rid="ref31">31</xref>-<xref ref-type="bibr" rid="ref32">32</xref>]. Respondents may become overwhelmed by the amount of information [<xref ref-type="bibr" rid="ref33">33</xref>] and may perceive ego depletion, leading to a reduced capacity to change [<xref ref-type="bibr" rid="ref34">34</xref>]. Furthermore, tailoring multiple behaviors simultaneously could fail to address any single behavior in sufficient depth [<xref ref-type="bibr" rid="ref3">3</xref>,<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref35">35</xref>]. On the other hand, addressing various behaviors simultaneously may optimize the occurrence of synergistic effects [<xref ref-type="bibr" rid="ref36">36</xref>-<xref ref-type="bibr" rid="ref40">40</xref>]. Hence, both strategies may have advantages as well as disadvantages. To our knowledge, there is no literature about the difference in completion and dropout rates between users of sequential and those of simultaneous behavior change interventions.</p>
            <p>In addition to the problem of dropout, another important aspect is that high-risk populations (such as the less-educated and people with many unhealthy behaviors) are often insufficiently reached [e.g. 41], and it is especially those with unhealthy behavior who should engage in online health interventions and spend enough time on the website [<xref ref-type="bibr" rid="ref42">42</xref>]. It is essential to identify the characteristics of people who complete or fail to complete online health interventions. In a study by Brouwer et al. [<xref ref-type="bibr" rid="ref25">25</xref>], respondents who completed the program were mostly female, middle-aged (40 to 50 years), and medium-educated, and had a healthier lifestyle. This information about completers&#8217; characteristics can be used to improve tailored programs by making them more attractive to the individual user. </p>
            <p>In conclusion, computer-tailored technology addressing multiple behaviors is still in its infancy [<xref ref-type="bibr" rid="ref43">43</xref>-<xref ref-type="bibr" rid="ref45">45</xref>]. It is unknown how much information people can and will handle in multiple behavior change interventions. In this study, we investigated the level of completion of a web-based tailored intervention addressing 5 lifestyle behaviors (physical activity, fruit consumption, vegetable consumption, alcohol intake, and smoking), and tested potential information overload by comparing dropout rates for two versions of the program, one offering a single behavior change module as part of a sequential program and one providing simultaneous tailored feedback on different behaviors. In addition, this study investigated personal predictors of dropout for the two versions of our computer-tailored program.</p>
        </sec>
        <sec sec-type="methods">
            <title>Methods</title>
            <sec>
                <title>Design</title>
                <p>In this study, which was part of a randomized controlled trial (Dutch Trial Register NTR2168), tailored information was provided to two groups, one receiving a sequential behavior tailoring condition (referred to below as sequential condition) and one receiving a simultaneous behavior tailoring condition (simultaneous condition) [<xref ref-type="bibr" rid="ref46">46</xref>]. The only difference between the conditions was that in the sequential condition, respondents were invited to focus their attention first on a single behavior for which they failed to meet the Dutch national recommendations, whereas the simultaneous condition addressed all behaviors for which they failed to meet the Dutch recommendations at once. A detailed description of the study protocol has been published elsewhere [<xref ref-type="bibr" rid="ref46">46</xref>].</p>
            </sec>
            <sec>
                <title>Participants and Procedure</title>
                <p>In the autumn of 2009, several Dutch Regional Health Authorities in the provinces of North-Brabant and Zeeland conducted an <italic>Adult Health Monitor</italic> study among adults (19-64 years) living in these provinces. This web-based questionnaire included demographics, aspects of general health and health-related topics. It also included questions regarding the respondents&#8217; lifestyle behaviors (physical activity, fruit and vegetable consumption, alcohol intake, and smoking). Completion took an average of 36 minutes (SD = 15.8). At the end of the questionnaire, respondents received information about the tailored program. When interested in this program, they could fill in their e-mail address. The eligibility criteria were participation in the <italic>Adult Health Monitor</italic> study, a valid e-mail address, and computer / Internet literacy. Approximately 3 weeks after completing the monitor questionnaire, participants interested in receiving tailored feedback received an e-mail enabling them to log on to the computer tailored program (see <xref ref-type="fig" rid="figure1">Figure 1</xref>). After approximately one month, people who did not respond to this e-mail received a reminder e-mail.</p>
                <fig id="figure1" position="float">
                    <label>Figure 1</label>
                    <caption>
                        <p>Screenshot of the homepage of the intervention program.</p>
                    </caption>
                    <graphic xlink:href="jmir_v14i2e26_fig1.JPG" alt-version="no" mimetype="image" position="float" xlink:type="simple" />
                </fig>
            </sec>
            <sec>
                <title>Intervention</title>
                <p>The aim of the intervention was to stimulate participants to improve their lifestyle, focusing on 5 health behaviors. Based on the respondents&#8217; answers to the different questions, an expert system selected the appropriate feedback messages from a large database and presented these directly on the respondent&#8217;s computer screen [<xref ref-type="bibr" rid="ref46">46</xref>]. The I-Change model [<xref ref-type="bibr" rid="ref47">47</xref>] was used as a theoretical framework for the questionnaires and the tailored advice.</p>
                <p>The first part of the feedback consisted of a health risk appraisal. Based on their answers on the <italic>Adult Health Monitor</italic> questionnaire, respondents received feedback concerning their lifestyle and information about whether they were meeting the public health guidelines defined for the 5 health behaviors, namely being moderately physically active for 30 minutes on at least five days a week; eating 200 g of vegetables per day; eating 2 pieces of fruit per day; not drinking more than 1 (women) or 2 (men) glasses of alcohol a day; and not smoking. In addition to more detailed information about the guidelines and the specific health behavior, respondents&#8217; scores were depicted graphically in the form of a traffic light (indicating whether they met, almost met, or did not meet the guideline) as well a bar chart comparing the respondents&#8217; behavior with the guideline for this behavior. At the end of the health risk appraisal, respondents received an overview illustrating their lifestyle behavior status (see <xref ref-type="fig" rid="figure2">Figure 2</xref>).</p>
                <p>Afterwards, in the second part of the program, personal advice was provided, based on additional questions about psychosocial determinants (ie, attitude, social influence, preparatory action plans, self-efficacy, and coping plans; see <xref ref-type="fig" rid="figure3">Figures 3</xref> and <xref ref-type="fig" rid="figure4">4</xref>), on one or more lifestyle behaviors, depending on the tailoring condition.</p>
                <fig id="figure2" position="float">
                    <label>Figure 2</label>
                    <caption>
                        <p>Screenshot of the health risk appraisal.</p>
                    </caption>
                    <graphic xlink:href="jmir_v14i2e26_fig2.JPG" alt-version="no" mimetype="image" position="float" xlink:type="simple" />
                </fig>
                <fig id="figure3" position="float">
                    <label>Figure 3</label>
                    <caption>
                        <p>Screenshot of items regarding the pros and cons of alcohol intake.</p>
                    </caption>
                    <graphic xlink:href="jmir_v14i2e26_fig3.JPG" alt-version="no" mimetype="image" position="float" xlink:type="simple" />
                </fig>
                <fig id="figure4" position="float">
                    <label>Figure 4</label>
                    <caption>
                        <p>Screenshot of a personal advice regarding the pros of alcohol intake.</p>
                    </caption>
                    <graphic xlink:href="jmir_v14i2e26_fig4.JPG" alt-version="no" mimetype="image" position="float" xlink:type="simple" />
                </fig>
                <sec>
                    <title>Sequential Condition</title>
                    <p>After receiving the health risk appraisal, individuals in the sequential condition were invited to choose one of the health behaviors for which they were currently failing to meet the guideline. Respondents were encouraged to select the behavior that they were most motivated to change. This was followed by a progressive scheme consisting of 4 steps, in which respondents received personal advice based on various psychosocial constructs: (1) attitude, (2) social influence, (3) preparatory plans, and (4) self-efficacy and coping plans regarding the lifestyle behavior that they had chosen. Personal advice was given after the questions about each psychosocial construct (ie, attitude questions were followed by personal feedback about these items).</p>
                </sec>
                <sec>
                    <title>Simultaneous Condition</title>
                    <p>After receiving the health risk appraisal, participants in the simultaneous condition received feedback on all behaviors for which they failed to adhere to the public health guidelines in a predefined order. At random, half of the respondents started with the modules addressing preventive health behaviors (ie, (1) physical activity, (2) vegetable consumption, (3) fruit consumption) and ended with the modules addressing addiction behaviors (ie, (4) alcohol intake, (5) smoking), whereas the other half passed through the modules in reversed order. Respondents were presented with additional questions concerning psychosocial constructs, as well as personal advice on all behaviors for which they failed to adhere to the lifestyle recommendations. The 4-step progressive scheme ((1) attitude, (2) social influence, (3) preparatory plans, and (4) self-efficacy and coping plans) was used for all relevant lifestyle behaviors. Again, questions and personal advice were presented alternately.</p>
                </sec>
            </sec>
            <sec>
                <title>Measures</title>
                <sec>
                    <title>Demographic Information</title>
                    <p>The following demographic variables were assessed: age, gender, educational level (no education, primary, or lower vocational school (low); secondary vocational school or high school (medium); or higher professional education or university (high)), income, current job status, marital status, number of persons in the household, and country of origin.</p>
                </sec>
                <sec>
                    <title>Health Status</title>
                    <p>Quality of life was assessed using the SF-12 Health Survey [<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref49">49</xref>]. Symptoms of depression and anxiety were assessed by the Kessler Psychological Distress Scale (K10) [<xref ref-type="bibr" rid="ref50">50</xref>]. Body mass index (BMI) was estimated from questions about height and weight.</p>
                </sec>
                <sec>
                    <title>Lifestyle Behaviors</title>
                    <p>Five lifestyle behaviors were assessed using validated questionnaires: (1) physical activity, (2) fruit consumption, (3) vegetable consumption, (4) alcohol intake, and (5) smoking.</p>
                    <p>Physical activity was measured by the Short QUestionnaire to ASsess Health-enhancing physical activity (SQUASH) [<xref ref-type="bibr" rid="ref51">51</xref>], and guideline adherence was assessed using procedures developed by Ainsworth et al. [<xref ref-type="bibr" rid="ref52">52</xref>].</p>
                    <p>Fruit consumption was measured using a 4-item Food Frequency Questionnaire (FFQ) assessing weekly fruit and fruit juice intake [<xref ref-type="bibr" rid="ref53">53</xref>].</p>
                    <p>Vegetable consumption was measured using a 4-item FFQ assessing the weekly consumption of boiled or baked vegetables, as well as salads or raw vegetables [<xref ref-type="bibr" rid="ref53">53</xref>].</p>
                    <p>Alcohol intake was measured by the 5-item Dutch Quantity-Frequency-Variability (QFV) questionnaire [<xref ref-type="bibr" rid="ref54">54</xref>].</p>
                    <p>Smoking was assessed by asking participants if they smoked, what they smoked (cigarettes, cigars, or pipe tobacco), and how much they smoked per day (cigarettes) or per week (cigars or pipe tobacco).</p>
                </sec>
                <sec>
                    <title>Psychosocial Determinants</title>
                    <p>The following description of the psychosocial determinants that were assessed is presented here to provide an overview of the program; the data on these items were not included in the analysis. Based on earlier studies [<xref ref-type="bibr" rid="ref15">15</xref>], various psychosocial factors were assessed for the five different lifestyle behaviors: <italic>attitude</italic> (6 items, such as &#8220;Eating 2 pieces of fruit every day is good for my health&#8221; &#8211; totally disagree to totally agree); <italic>social influence</italic> (3 items, such as &#8220;How many people in your direct environment smoke?&#8221; &#8211; nobody to everybody); <italic>self-efficacy</italic> (6 items, such as &#8220;I am able to eat sufficient vegetables when I have other delicious food at home&#8221; &#8211; no, definitely not to yes, definitely); <italic>preparatory plans</italic> (3 items, such as &#8220;I intend to allow time for physical activity&#8221; &#8211; no, definitely not to yes, definitely); and <italic>coping plans</italic> (6 items, such as &#8220;I have made a plan to drink no more than 2 glasses of alcohol when I feel stressed or nervous&#8221; &#8211; totally disagree to totally agree).</p>
                </sec>
                <sec>
                    <title>Program Use</title>
                    <p>We counted the time respondents spent on the website during their first visit (ie, from logging in to the program until logging out or closing the website). Furthermore, we assessed the number of respondents who started with the first module and the number of respondents who filled out the program completely.</p>
                </sec>
            </sec>
            <sec>
                <title>Statistical Analyses</title>
                <p>The data was analyzed using SPSS software, version 17.0. Descriptive statistics were used to describe the characteristics of the study sample and to calculate the dropout rates for the 2 tailoring conditions. In the sequential condition, a completer was defined as someone who filled in one module from start to finish (ie, including the final question) since the aim of the first visit was that respondents of this condition complete one module relating to a lifestyle behavior for which they failed to adhere to the guideline. In the simultaneous condition, a completer was defined as someone who completed all modules relating to the lifestyle behaviors for which they failed to adhere to the guidelines. The groups (ie, completers versus non-completers) were compared in terms of their demographics and lifestyle behaviors by means of Chi-square tests for discrete variables and independent-samples <italic>t</italic> tests for continuous variables. In addition, effect sizes (ES) were calculated based on means (Cohen&#8217;s <italic>d</italic>) and percentages (categorical variables). Effect sizes below 0.30 are considered small, while those between 0.30 and 0.80 are considered medium, and those larger than 0.80 are considered large [<xref ref-type="bibr" rid="ref55">55</xref>]. Chi-square tests as well as effect size calculations were also used to explore differences between the tailoring conditions in terms of their completion rates, based on the number of guidelines that respondents failed to meet. Logistic regression analyses, using the Enter method, were used to identify predictors of program completion (demographics, health status, lifestyle behaviors and condition) within the entire sample. To identify interaction effects of tailoring condition and possible predictors, interaction terms were added to the regression equation. In the case of a significant interaction, logistic regression analyses were done separately for the two tailoring conditions to identify the predictors (demographics, health status, lifestyle behaviors).</p>
            </sec>
        </sec>
        <sec sec-type="results">
            <title>Results</title>
            <sec>
                <title>Participants&#8217; Characteristics</title>
                <p>A total of 3473 individuals participated in the present study. The mean age of the participants was 44 years. Slightly more men than women took part. With regard to the participants&#8217; lifestyle, 17.4% (n = 608) failed to meet the physical activity guidelines, 67.4% (n = 2323) did not eat enough vegetables, 54.6% (n = 1873) did not eat enough fruit, 28.2% (n = 978) drank too much alcohol, and 19.0% (n = 660) reported that they smoked. Almost two-thirds did not adhere to two or more health behavior guidelines (n = 2106; 61.7%). The characteristics of the total sample are listed in <xref ref-type="table" rid="table1">Table 1</xref>.</p>
                <table-wrap id="table1" position="float">
                    <label>Table 1</label>
                    <caption>
                        <p> Demographics, health status and lifestyle of the study sample (N = 3473)</p>
                    </caption>
                    <table cellpadding="8" cellspacing="0" border="1" rules="groups" frame="hsides" width="1000">
                        <col width="10" />
                        <col width="490" />
                        <col width="500" />
                        <thead>
                            <tr valign="top">
                                <td colspan="2">  Variable  </td>
                                <td>  Total group  </td>
                            </tr>
                        </thead>
                        <tbody>
                            <tr valign="top">
                                <td colspan="2">
                                    <bold>Age</bold>, n = 3473  </td>
                                <td>  43.61 (19-64; SD = 12.60)  </td>
                            </tr>
                            <tr valign="top">
                                <td colspan="2">
                                    <bold>Gender</bold>, n = 3473  </td>
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td>  Male  </td>
                                <td>  1849 (53.2%)  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td>  Female  </td>
                                <td>  1624 (46.8%)  </td>
                            </tr>
                            <tr valign="top">
                                <td colspan="2">
                                    <bold>Education</bold>, n = 3458  </td>
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td>  Low  </td>
                                <td>  367 (10.6%)  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td>  Medium  </td>
                                <td>  1607 (46.5%)  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td>  High  </td>
                                <td>  1483 (42.9%)  </td>
                            </tr>
                            <tr valign="top">
                                <td colspan="2">
                                    <bold>Income per month</bold>, n = 3468  </td>
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td>  &#60; &#8364; 1000  </td>
                                <td>  226 (6.5%)  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td>  &#8364; 1001 - &#8364; 1350  </td>
                                <td>  228 (6.6%)  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td>  &#8364; 1351 - &#8364; 1750  </td>
                                <td>  373 (10.8%)  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td>  &#8364; 1750 - &#8364; 3050  </td>
                                <td>  1177 (33.9%)  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td>  &#62; &#8364; 3051  </td>
                                <td>  976 (28.1%)  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td>  &#8220;I don&#8217;t want to say&#8221;  </td>
                                <td>  488 (14.1%)  </td>
                            </tr>
                            <tr valign="top">
                                <td colspan="2">
                                    <bold>Employment situation</bold>, n = 3467  </td>
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td>  Employed  </td>
                                <td>  2655 (76.6%)  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td>  Studying  </td>
                                <td>  229 (6.6%)  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td>  Homemaker  </td>
                                <td>  176 (5.1%)  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td>  Not currently in employment  </td>
                                <td>  407 (11.7%)  </td>
                            </tr>
                            <tr valign="top">
                                <td colspan="2">
                                    <bold>Marital status</bold>, n = 3457  </td>
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td>  Married  </td>
                                <td>  2092 (60.5%)  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td>  Living together  </td>
                                <td>  528 (15.3%)  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td>  Unmarried  </td>
                                <td>  639 (18.5%)  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td>  Divorced  </td>
                                <td>  170 (4.9%)  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td>  Widowed  </td>
                                <td>  28 (0.8%)  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td>  # persons in household n = 3473  </td>
                                <td>  2.91 (1-20; SD = 1.42)  </td>
                            </tr>
                            <tr valign="top">
                                <td colspan="2">
                                    <bold>Native country</bold>, n = 3471  </td>
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td>  The Netherlands  </td>
                                <td>  3300 (95.1%)  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td>  Other  </td>
                                <td>  171 (4.9%)  </td>
                            </tr>
                            <tr valign="top">
                                
                                <td colspan="2">  <bold>BMI</bold>, n = 3445  </td>
                                <td>  25.17 (15.03-58.11; SD = 3.96)  </td>
                            </tr>
                            <tr valign="top">
                                <td colspan="2">  <bold>Quality of Life</bold>, n = 3452  </td>
                                <td>  40.11 (16-48; SD = 5.15)  </td>
                            </tr>
                            <tr valign="top">
                                <td colspan="2">  <bold>K10 (psychological distress)</bold>, n = 3461  </td>
                                <td>  44.78 (12-50; SD = 5.70)  </td>
                            </tr>
                            <tr valign="top">
                                <td colspan="2">
                                    <bold>Number of guidelines complied with</bold>, n = 3411  </td>
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td>  0  </td>
                                <td>  25 (0.7%)  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td>  1  </td>
                                <td>  226 (6.6%)  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td>  2  </td>
                                <td>  681 (20.0%)  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td>  3  </td>
                                <td>  1174 (34.4%)  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td>  4  </td>
                                <td>  947 (27.8%)  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td>  5  </td>
                                <td>  358 (10.5%)  </td>
                            </tr>
                            <tr valign="top">
                                <td colspan="3" />
                            </tr>
                            <tr valign="top">
                                <td colspan="2">
                                    <bold>Physical activity</bold>, n = 3473  </td>
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td>  Compliance  </td>
                                <td>  2865 (82.5%)  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td>  Non-compliance  </td>
                                <td>  608 (17.4%)  </td>
                            </tr>
                            <tr valign="top">
                                <td colspan="2">
                                    <bold>Vegetable consumption</bold>, n = 3446  </td>
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td>  Compliance  </td>
                                <td>  1123 (32.6%)  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td>  Non-compliance  </td>
                                <td>  2323 (67.4%)  </td>
                            </tr>
                            <tr valign="top">
                                <td colspan="2">
                                    <bold>Fruit consumption</bold>, n = 3433  </td>
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td>  Compliance  </td>
                                <td>  1560 (45.4%)  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td>  Non-compliance  </td>
                                <td>  1873 (54.6%)  </td>
                            </tr>
                            <tr valign="top">
                                <td colspan="2">
                                    <bold>Alcohol intake</bold>, n = 3473  </td>
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td>  Compliance  </td>
                                <td>  2495 (71.8%)  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td>  Non-compliance  </td>
                                <td>  978 (28.2%)  </td>
                            </tr>
                            <tr valign="top">
                                <td colspan="2">
                                    <bold>Smoking</bold>, n = 3473  </td>
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td>  Compliance  </td>
                                <td>  2813 (81.0%)  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td>  Non-compliance  </td>
                                <td>  660 (19.0%)  </td>
                            </tr>
                        </tbody>
                    </table>
                </table-wrap>
            </sec>
            <sec>
                <title>Completion and Dropout</title>
                <p>As shown in <xref ref-type="fig" rid="figure5">Figure 5</xref>, the 3473 people who logged on to the program were evenly randomized to the 2 tailoring conditions. A total of 358 respondents (10.3%) adhered to all 5 health guidelines. These people were not included in our further analyses, as no specific completion moment could be defined for this group. Of the remaining 3115 respondents, 1325 (42.5%) logged out immediately after receiving the health risk appraisal, and 62 (2.0%) even before receiving the health risk appraisal: in the sequential condition, 53.5% (n = 821) started one lifestyle module, while in the simultaneous condition, 59.8% (n = 907) started at least the first lifestyle module (&#967;<sup>2</sup>
                    <sub>1</sub> = 12.48; <italic>P</italic> &#60; .001). Of the 821 starters in the sequential condition, 65.5% (n = 538) completed the module, while of the 907 starters in the simultaneous condition, 38.4% (n = 348) completed the whole program (&#967;<sup>2</sup>
                    <sub>1</sub> = 127.25; <italic>P</italic> &#60; .001).</p>
                <p>On average, respondents in the sequential condition spent 10 minutes and 8 seconds on the web-based tailored program, while respondents in the simultaneous condition spent an average of 9 minutes and 47 seconds. In the sequential condition, respondents completed the program on average within 18 minutes and 10 seconds, while non-completers spent an average of 6 minutes and 20 seconds on the program. In the simultaneous condition, respondents completed the program within 20 minutes and 52 seconds, while non-completers left the program on average after 6 minutes and 16 seconds.</p>
                <sec>
                    <title>The Influence of Guideline Adherence Level on Dropout</title>
                    <p>The completion rate generally decreased as the number of guidelines that the respondents failed to meet increased (see <xref ref-type="fig" rid="figure6">Figure 6</xref>). However, this decline of the completion rates differed between the two conditions. Respondents in the simultaneous condition who failed to adhere to 2 or more guidelines were more likely to leave the site prematurely than those in the sequential condition who failed to adhere to the same number of guidelines.</p>
                </sec>
            </sec>
            <sec>
                <title>Differences between Completers and Non-Completers</title>
                <p>The 2 tailoring groups did not differ in terms of their demographics, health status or lifestyle behaviors, indicating that randomization had been successful. A comparison of respondents who filled in the entire program (ie, completers) with respondents who prematurely left the site (ie, non-completers) showed that the two groups differed on all variables, except for income, native country, K10 and alcohol intake (see <xref ref-type="table" rid="table2">Table 2</xref>). Medium effect sizes regarding these differences concerned age and the number of guidelines respondents adhered to. Completers were older than non-completers were and completers adhered to more health guidelines than non-completers did.</p>
                <fig id="figure5" position="float">
                    <label>Figure 5</label>
                    <caption>
                        <p>Attrition diagram.</p>
                    </caption>
                    <graphic xlink:href="jmir_v14i2e26_fig5.jpg" alt-version="no" mimetype="image" position="float" xlink:type="simple" />
                </fig>
                <fig id="figure6" position="float">
                    <label>Figure 6</label>
                    <caption>
                        <p>Number of guidelines respondents failed to adhere to against the number of completers in the sequential condition (n = 1536) and the simultaneous condition (n = 1517).</p>
                    </caption>
                    <graphic xlink:href="jmir_v14i2e26_fig6.jpg" alt-version="no" mimetype="image" position="float" xlink:type="simple" />
                </fig>
                <table-wrap id="table2" position="float">
                    <label>Table 2</label>
                    <caption>
                        <p> Differences in demographics, health status and lifestyle between non-completers and completers (N = 3053)</p>
                    </caption>
                    <table cellpadding="8" cellspacing="0" border="1" rules="groups" frame="hsides" width="1000">
                        <col width="10" />
                        <col width="10" />
                        <col width="290" />
                        <col width="169" />
                        <col width="169" />
                        <col width="153" />
                        <col width="153" />
                        <col width="68" />
                        <thead>
                            <tr valign="top">
                                <td colspan="3">  Variable  </td>
                                <td>  Non-completer<break />  n = 2167  </td>
                                <td>  Completers  <break />    n = 886  </td>
                                <td>
                                    <italic>T (P)</italic>
                                </td>
                                <td>
                                    <italic>&#967;<sup>2</sup> (P)</italic>
                                </td>
                                <td>
                                    <italic>ES</italic>
                                </td>
                            </tr>
                        </thead>
                        <tbody>
                            <tr valign="top">
                                <td colspan="3">
                                    <bold>Age</bold>
                                </td>
                                <td>  41.85 (SD = 12.64)  </td>
                                <td>  47.21 (SD = 11.96)  </td>
                                <td>  11.07 (<italic>P</italic> &#60; .001)  </td>
                                <td />
                                <td>
                                    0.43
                                </td>
                            </tr>
                            <tr valign="top">
                                <td colspan="3">
                                    <bold>Gender</bold>
                                </td>
                                <td />
                                <td />
                                <td colspan="3" />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td colspan="2">  Male  </td>
                                <td>  1202 (55.5%)  </td>
                                <td>  450 (50.8%)  </td>
                                <td />
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td colspan="2">  Female  </td>
                                <td>  965 (44.5%)  </td>
                                <td>  435 (49.2%)  </td>
                                <td />
                                <td>  6.58 (<italic>P</italic> = .037)  </td>
                                <td>  0.09  </td>
                            </tr>
                            <tr valign="top">
                                <td colspan="4">
                                    <bold>Education</bold>
                                </td>
                                <td />
                                <td />
                                <td colspan="3" />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td colspan="2">  Low  </td>
                                <td>  212 (9.8%)  </td>
                                <td>  120 (13.6%)  </td>
                                <td />
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td colspan="2">  Medium  </td>
                                <td>  1007 (46.7%)  </td>
                                <td>  424 (48.0%)  </td>
                                <td />
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td colspan="2">  High  </td>
                                <td>  938 (43.5%)  </td>
                                <td>  339 (38.4%)  </td>
                                <td />
                                <td>  13.35 (<italic>P</italic> = .010)  </td>
                                <td>  0.13  </td>
                            </tr>
                            <tr valign="top">
                                <td colspan="3">
                                    <bold>Income per month <sup>a</sup>
                                    </bold>
                                </td>
                                <td />
                                <td />
                                <td colspan="3" />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td colspan="2">  &#60; &#8364; 1750  </td>
                                <td>  504 (23.3%)  </td>
                                <td>  221 (25.0%)  </td>
                                <td />
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td colspan="2">  &#8364; 1751 - &#8364; 3050  </td>
                                <td>  1040 (48.0%)  </td>
                                <td>  437 (49.5%)  </td>
                                <td />
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td colspan="2">  &#62; &#8364; 3051  </td>
                                <td>  621 (28.7%)  </td>
                                <td>  225 (25.5%)  </td>
                                <td />
                                <td>  4.46 (<italic>P</italic> = .347)  </td>
                                <td>  0.08  </td>
                            </tr>
                            <tr valign="top">
                                <td colspan="3">
                                    <bold>Employment situation</bold>
                                </td>
                                <td />
                                <td />
                                <td colspan="3" />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td colspan="2">  Job  </td>
                                <td>  1852 (85.6%)  </td>
                                <td>  686 (77.7%)  </td>
                                <td />
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td colspan="2">  No job  </td>
                                <td>  311 (14.4%)  </td>
                                <td>  197 (22.3%)  </td>
                                <td />
                                <td>  33.34 (<italic>P</italic> &#60; .001)  </td>
                                <td>  0.21  </td>
                            </tr>
                            <tr valign="top">
                                <td colspan="3">
                                    <bold>Relationship status</bold>
                                </td>
                                <td />
                                <td />
                                <td colspan="3" />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td colspan="2">  Single  </td>
                                <td>  557 (25.8%)  </td>
                                <td>  191 (21.8%)  </td>
                                <td />
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td colspan="2">  In relationship  </td>
                                <td>  1602 (74.2%)  </td>
                                <td>  687 (78.2%)  </td>
                                <td />
                                <td>  8.56 (<italic>P</italic> = .014)  </td>
                                <td>  0.11  </td>
                            </tr>
                            <tr valign="top">
                                <td colspan="3">
                                    <bold># persons in household</bold>
                                </td>
                                <td>  2.99 (SD = 1.45)  </td>
                                <td>  2.74 (SD = 1.25)  </td>
                                <td>  -4.86 (<italic>P</italic> &#60; .001)  </td>
                                <td />
                                <td>  0.18  </td>
                            </tr>
                            <tr valign="top">
                                <td colspan="3">
                                    <bold>Native country</bold>
                                </td>
                                <td />
                                <td />
                                <td colspan="3" />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td colspan="2">  The Netherlands  </td>
                                <td>  2075 (95.8%)  </td>
                                <td>  838 (94.7%)  </td>
                                <td />
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td colspan="2">  Other  </td>
                                <td>  91 (4.2%)  </td>
                                <td>  46 (5.3%)  </td>
                                <td />
                                <td>  1.52 (<italic>P</italic> = .468)  </td>
                                <td>  0.05  </td>
                            </tr>
                            <tr valign="top">
                                <td colspan="3">
                                    <bold>BMI</bold>
                                </td>
                                <td>  25.00 (SD = 3.93)  </td>
                                <td>  25.54 (SD = 3.84)  </td>
                                <td>  3.47 (<italic>P</italic> = .001)  </td>
                                <td />
                                <td>  0.14  </td>
                            </tr>
                            <tr valign="top">
                                <td colspan="3">
                                    <bold>Quality of Life</bold>
                                </td>
                                <td>  40.19 (SD = 5.06)  </td>
                                <td>  39.39 (SD = 5.64)  </td>
                                <td>  -3.64 (<italic>P</italic> &#60; .001)  </td>
                                <td />
                                <td>  0.15  </td>
                            </tr>
                            <tr valign="top">
                                <td colspan="3">
                                    <bold>K10</bold>
                                </td>
                                <td>  44.71 (SD = 5.75)  </td>
                                <td>  44.41 (SD = 6.12)  </td>
                                <td>  -1.27 (<italic>P</italic> = .203)  </td>
                                <td />
                                <td>  0.05  </td>
                            </tr>
                            <tr valign="top">
                                <td colspan="3">
                                    <bold>Adherence to guidelines</bold>
                                </td>
                                <td>  2.83 (SD = .96)  </td>
                                <td>  3.12 (SD = .88)  </td>
                                <td>  8.22 (<italic>P</italic> &#60; .001)  </td>
                                <td />
                                <td>0.31
                                </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td colspan="2">
                                    <bold>Physical activity</bold>
                                </td>
                                <td />
                                <td />
                                <td colspan="3" />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td />
                                <td>  Compliance  </td>
                                <td>  1698 (78.4%)  </td>
                                <td>  761 (86.0%)  </td>
                                <td />
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td />
                                <td>  Non-compliance  </td>
                                <td>  469 (21.6%)  </td>
                                <td>  124 (14.0%)  </td>
                                <td />
                                <td>  23.62 (<italic>P</italic> &#60; .001)  </td>
                                <td>  0.18  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td colspan="2">
                                    <bold>Vegetable consumption</bold>
                                </td>
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td />
                                <td>  Compliance  </td>
                                <td>  501 (23.1%)  </td>
                                <td>  253 (28.6%)  </td>
                                <td />
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td />
                                <td>  Non-compliance  </td>
                                <td>  1666 (76.9%)  </td>
                                <td>  632 (71.4%)  </td>
                                <td />
                                <td>  10.43 (<italic>P</italic> = .005)  </td>
                                <td>  0.12  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td colspan="2">
                                    <bold>Fruit consumption</bold>
                                </td>
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td />
                                <td>  Compliance  </td>
                                <td>  801 (37.0%)  </td>
                                <td>  388 (43.8%)  </td>
                                <td />
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td />
                                <td>  Non-compliance  </td>
                                <td>  1366 (63.0%)  </td>
                                <td>  497 (56.2%)  </td>
                                <td />
                                <td>  13.14 (<italic>P</italic> = .001)  </td>
                                <td>  0.13  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td colspan="2">
                                    <bold>Alcohol intake</bold>
                                </td>
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td />
                                <td>  Compliance  </td>
                                <td>  1459 (67.3%)  </td>
                                <td>  632 (71.4%)  </td>
                                <td />
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td />
                                <td>  Non-compliance  </td>
                                <td>  708 (32.7%)  </td>
                                <td>  253 (28.6%)  </td>
                                <td />
                                <td>  5.32 (<italic>P</italic> = .070)  </td>
                                <td>  0.08  </td>
                            </tr>
                            <tr valign="top">
                                <td colspan="8" />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td colspan="2">
                                    <bold>Smoking</bold>
                                </td>
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td />
                                <td>  Compliance  </td>
                                <td>  1671 (77.1%)  </td>
                                <td>  731 (82.5%)  </td>
                                <td />
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td />
                                <td>  Non-compliance  </td>
                                <td>  496 (22.9%)  </td>
                                <td>  154 (17.4%)  </td>
                                <td />
                                <td>  11.56 (<italic>P</italic> = .003)  </td>
                                <td>  0.12  </td>
                            </tr>
                            <tr valign="top">
                                <td colspan="3">
                                    <bold>Condition</bold>
                                </td>
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td colspan="2">  Sequential  </td>
                                <td>  998 (46.1%)  </td>
                                <td>  537 (60.7%)  </td>
                                <td />
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td colspan="2">  Simultaneous  </td>
                                <td>  1169 (53.9%)  </td>
                                <td>  348 (39.3%)  </td>
                                <td />
                                <td>  54.74 (<italic>P</italic> &#60; .001)  </td>
                                <td>  0.27  </td>
                            </tr>
                        </tbody>
                    </table>
                    <table-wrap-foot>
                        <fn id="table2fn1">
                            <p>
                                <sup>a</sup> Note: Respondents who did not want to report their income were classified in the category &#8220;&#8364; 1751 - &#8364; 3050&#8221;</p>
                        </fn>
                    </table-wrap-foot>
                </table-wrap>
            </sec>
            <sec>
                <title>Predictors of Program Completion</title>
                <p>We performed a logistic regression analysis to identify predictors of program completion. After the various interaction terms had been added, the interaction term &#8216;tailoring condition*non-adherence to guidelines&#8217; emerged as statistically significant (B = -.620; <italic>P</italic> &#60; .001) indicating that the effect of the number of guidelines respondents failed to adhere to on their completion status depended on the tailoring condition. Hence, separate analyses were performed for the 2 tailoring conditions. The results are presented in <xref ref-type="table" rid="table3">Table 3</xref> (sequential condition) and <xref ref-type="table" rid="table4">Table 4</xref> (simultaneous condition).</p>
                <p>In model 1 of both conditions, the factors significantly associated with non-completion were a lower age and being male. In the simultaneous condition, Dutch nationality was also significantly associated with dropout. In model 2, the effect of age remained significant in both conditions. In the sequential condition, being male continued to make a significant contribution, whereas in the simultaneous condition, the gender and native country variables became non-significant. In both conditions, discontinuation of the program was predicted by the number of guidelines respondents failed to adhere to (in addition to a younger age). This means that people with a less healthy lifestyle were more likely to drop out than those with a healthier lifestyle. The second model of the sequential condition explained 8.2% of the total variance for program completion, whereas the second model of the simultaneous condition explained 15.1% of the total variance.</p>
                <table-wrap id="table3" position="float">
                    <label>Table 3</label>
                    <caption>
                        <p>Results of logistic regression analyses (Enter method) among the sequential condition on demographics and health status (model 1) and number of guidelines respondents failed to adhere to (model 2), with completion status (non-completers = 0; completers = 1) as dependent variable (N = 1496)</p>
                    </caption>
                    <table cellpadding="8" cellspacing="0" border="1" rules="groups" frame="hsides" width="1000">
                        <col width="10" />
                        <col width="10" />
                        <col width="286" />
                        <col width="104" />
                        <col width="100" />
                        <col width="120" />
                        <col width="60" />
                        <col width="100" />
                        <col width="100" />
                        <col width="120" />
                        <thead>
                            <tr valign="top">
                                <td colspan="3" />
                                <td colspan="3">  Model 1  </td>
                                <td />
                                <td colspan="3">  Model 2  </td>
                            </tr>
                            <tr valign="top">
                                <td colspan="3">  Variable  </td>
                                <td>  OR  </td>
                                <td>
                                    <italic>P</italic>
                                </td>
                                <td>  CI  </td>
                                <td />
                                <td>  OR  </td>
                                <td>
                                    <italic>P</italic>
                                </td>
                                <td>  CI  </td>
                            </tr>
                        </thead>
                        <tbody>
                            <tr valign="top">
                                <td colspan="3">
                                    <bold>
                                        <italic>Demographics</italic>
                                    </bold>
                                </td>
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td colspan="2">
                                    <bold>Age</bold>
                                </td>
                                <td>  1.04  </td>
                                <td>  &#60; .001  </td>
                                <td>  1.02-1.05  </td>
                                <td />
                                <td>  1.04  </td>
                                <td>  &#60; .001  </td>
                                <td>  1.02-1.05  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td colspan="2">
                                    <bold>Gender</bold>
                                </td>
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td />
                                <td>  Male (ref.)  </td>
                                <td>  1.00  </td>
                                <td />
                                <td />
                                <td />
                                <td>  1.00  </td>
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td />
                                <td>  Female  </td>
                                <td>  1.30  </td>
                                <td>  .02  </td>
                                <td>  1.04-1.63  </td>
                                <td />
                                <td>  1.27  </td>
                                <td>  .04  </td>
                                <td>  1.01-1.59  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td colspan="2">
                                    <bold> Education</bold>
                                </td>
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td />
                                <td>  Low  </td>
                                <td>  1.42  </td>
                                <td>  .99  </td>
                                <td>  0.98-2.05  </td>
                                <td />
                                <td>  1.03  </td>
                                <td>  .90  </td>
                                <td>  0.69-1.53  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td />
                                <td>  Medium  </td>
                                <td>  1.13  </td>
                                <td>  .36  </td>
                                <td>  0.86-1.50  </td>
                                <td />
                                <td>  1.14  </td>
                                <td>  .30  </td>
                                <td>  0.89-1.45  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td />
                                <td>  High (ref.)  </td>
                                <td>  1.00  </td>
                                <td />
                                <td />
                                <td />
                                <td>  1.00  </td>
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td colspan="2">
                                    <bold>Income</bold>
                                    <sup>a</sup>
                                    <bold>per month</bold>
                                </td>
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td />
                                <td>  &#60; &#8364; 1750  </td>
                                <td>  1.42  </td>
                                <td>  .06  </td>
                                <td>  0.98-2.05  </td>
                                <td />
                                <td>  1.42  </td>
                                <td>  .07  </td>
                                <td>  0.98-2.05  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td />
                                <td>  &#8364; 1751 - &#8364; 3050  </td>
                                <td>  1.13  </td>
                                <td>  .38  </td>
                                <td>  0.86-1.50  </td>
                                <td />
                                <td>  1.13  </td>
                                <td>  .40  </td>
                                <td>  0.84-1.49  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td />
                                <td>  &#62; &#8364; 3051 (ref.)  </td>
                                <td>  1.00  </td>
                                <td />
                                <td />
                                <td />
                                <td>  1.00  </td>
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td colspan="2">
                                    <bold>Employment situation</bold>
                                </td>
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td />
                                <td>  Job (ref.)  </td>
                                <td>  1.00  </td>
                                <td />
                                <td />
                                <td />
                                <td>  1.00  </td>
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td />
                                <td>  No job  </td>
                                <td>  1.01  </td>
                                <td>  .96  </td>
                                <td>  0.74-1.38  </td>
                                <td />
                                <td>  1.01  </td>
                                <td>  .97  </td>
                                <td>  0.73-1.38  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td colspan="2">
                                    <bold>Relationship status</bold>
                                </td>
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td />
                                <td>  In relationship (ref.)  </td>
                                <td>  1.00  </td>
                                <td />
                                <td />
                                <td />
                                <td>  1.00  </td>
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td />
                                <td>  Single  </td>
                                <td>  0.94  </td>
                                <td>  .71  </td>
                                <td>  0.68-1.30  </td>
                                <td />
                                <td>  0.97  </td>
                                <td>  .83  </td>
                                <td>  0.70-1.33  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td colspan="2">
                                    <bold># persons in household</bold>
                                </td>
                                <td>  0.94  </td>
                                <td>  .18  </td>
                                <td>  0.87-1.03  </td>
                                <td />
                                <td>  0.94  </td>
                                <td>  .16  </td>
                                <td>  0.87-1.02  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td colspan="2">
                                    <bold>Native country</bold>
                                </td>
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td />
                                <td>  The Netherlands (ref.)  </td>
                                <td>  1.00  </td>
                                <td />
                                <td />
                                <td />
                                <td>  1.00  </td>
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td />
                                <td>  Other  </td>
                                <td>  0.99  </td>
                                <td>  .93  </td>
                                <td>  0.57-1.66  </td>
                                <td />
                                <td>  0.99  </td>
                                <td>  .96  </td>
                                <td>  0.58-1.68  </td>
                            </tr>
                            <tr valign="top">
                                <td colspan="3">
                                    <bold>
                                        <italic>Health status</italic>
                                    </bold>
                                </td>
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td />
                                <td>
                                    <bold>BMI</bold>
                                </td>
                                <td>  1.01  </td>
                                <td>  .57  </td>
                                <td>  0.98-1.04  </td>
                                <td />
                                <td>  1.01  </td>
                                <td>  .62  </td>
                                <td>  0.98-1.04  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td />
                                <td>  <bold>Quality of Life</bold>  </td>
                                <td>  0.97  </td>
                                <td>  .07  </td>
                                <td>  0.94-1.00  </td>
                                <td />
                                <td>  0.97  </td>
                                <td>  .05  </td>
                                <td>  0.94-1.00  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td />
                                <td>  <bold>K10</bold>  </td>
                                <td>  1.00  </td>
                                <td>  .75  </td>
                                <td>  0.98-1.03  </td>
                                <td />
                                <td>  1.00  </td>
                                <td>  .78  </td>
                                <td>  0.98-1.04  </td>
                            </tr>
                            <tr valign="top">
                                <td colspan="3">
                                    <bold>
                                        <italic>Non-adherence to guidelines</italic>
                                    </bold>
                                </td>
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td colspan="2">
                                    <bold>Number of guidelines</bold>
                                </td>
                                <td />
                                <td />
                                <td />
                                <td />
                                <td>  .86  </td>
                                <td>  .01  </td>
                                <td>  0.76-0.97  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td />
                                <td>  Nagelkerke&#8217;s R<sup>2</sup>
                                </td>
                                <td />
                                <td />
                                <td>  .076  </td>
                                <td />
                                <td />
                                <td />
                                <td>  .082  </td>
                            </tr>
                        </tbody>
                    </table>
                    <table-wrap-foot>
                        <fn id="table3fn1">
                            <p>
                                <sup>a</sup> Note: Respondents who did not want to report their income were classified in the category &#8220;&#8364; 1751 - &#8364; 3050&#8221;</p>
                        </fn>
                    </table-wrap-foot>
                </table-wrap>
                <table-wrap id="table4" position="float">
                    <label>Table 4</label>
                    <caption>
                        <p> Results of logistic regression analyses (Enter method) among the simultaneous condition on demographics and health status (model 1) and number of guidelines respondents failed to adhere to (model 2), with completion status (non-completers = 0; completers = 1) as dependent variable (N = 1473)</p>
                    </caption>
                    <table cellpadding="8" cellspacing="0" border="1" rules="groups" frame="hsides" width="1000">
                        <col width="10" />
                        <col width="10" />
                        <col width="277" />
                        <col width="103" />
                        <col width="100" />
                        <col width="120" />
                        <col width="60" />
                        <col width="100" />
                        <col width="100" />
                        <col width="120" />
                        <thead>
                            <tr valign="top">
                                <td colspan="3" />
                                <td colspan="3">  Model 1  </td>
                                <td />
                                <td colspan="3">  Model 2  </td>
                            </tr>
                            <tr valign="top">
                                <td colspan="3">  Variable  </td>
                                <td>  OR  </td>
                                <td>
                                    <italic>P</italic>
                                </td>
                                <td>  CI  </td>
                                <td />
                                <td>  OR  </td>
                                <td>
                                    <italic>P</italic>
                                </td>
                                <td>  CI  </td>
                            </tr>
                        </thead>
                        <tbody>
                            <tr valign="top">
                                <td colspan="3">
                                    <bold>
                                        <italic>Demographics</italic>
                                    </bold>
                                </td>
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td colspan="2">
                                    <bold>Age</bold>
                                </td>
                                <td>  1.04  </td>
                                <td>  &#60; .001  </td>
                                <td>  1.02-1.05  </td>
                                <td />
                                <td>  1.04  </td>
                                <td>  &#60; .001  </td>
                                <td>  1.02-1.05  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td colspan="2">
                                    <bold>Gender</bold>
                                </td>
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td />
                                <td>  Male (ref.)  </td>
                                <td>  1.00  </td>
                                <td />
                                <td />
                                <td />
                                <td>  1.00  </td>
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td />
                                <td>  Female  </td>
                                <td>  1.35  </td>
                                <td>  .03  </td>
                                <td>  1.04-1.74  </td>
                                <td />
                                <td>  1.13  </td>
                                <td>  .36  </td>
                                <td>  0.87-1.48  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td colspan="2">
                                    <bold>Education</bold>
                                </td>
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td />
                                <td>  Low  </td>
                                <td>  1.30  </td>
                                <td>  .22  </td>
                                <td>  0.86-1.95  </td>
                                <td />
                                <td>  1.41  </td>
                                <td>  .11  </td>
                                <td>  0.92-2.16  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td />
                                <td>  Medium  </td>
                                <td>  1.02  </td>
                                <td>  .88  </td>
                                <td>  0.77-1.35  </td>
                                <td />
                                <td>  1.09  </td>
                                <td>  .55  </td>
                                <td>  0.82-1.46  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td />
                                <td>  High (ref.)  </td>
                                <td>  1.00  </td>
                                <td />
                                <td />
                                <td />
                                <td>  1.00  </td>
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td colspan="2">
                                    <bold>Income</bold>
                                    <sup>a</sup>
                                    <bold>per month</bold>
                                </td>
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td />
                                <td>  &#60; &#8364; 1750  </td>
                                <td>  0.91  </td>
                                <td>  .65  </td>
                                <td>  0.60-1.38  </td>
                                <td />
                                <td>  0.87  </td>
                                <td>  .51  </td>
                                <td>  0.56-1.33  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td />
                                <td>  &#8364; 1751 - &#8364; 3050  </td>
                                <td>  0.89  </td>
                                <td>  .44  </td>
                                <td>  0.65-1.21  </td>
                                <td />
                                <td>  0.90  </td>
                                <td>  .51  </td>
                                <td>  0.65-1.24  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td />
                                <td>  &#62; &#8364; 3051 (ref.)  </td>
                                <td>  1.00  </td>
                                <td />
                                <td />
                                <td />
                                <td>  1.00  </td>
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td colspan="2">
                                    <bold>Employment situation</bold>
                                </td>
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td />
                                <td>  Job (ref.)  </td>
                                <td>  1.00  </td>
                                <td />
                                <td />
                                <td />
                                <td>  1.00  </td>
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td />
                                <td>  No job  </td>
                                <td>  1.18  </td>
                                <td>  .35  </td>
                                <td>  0.84-1.66  </td>
                                <td />
                                <td>  1.11  </td>
                                <td>  .56  </td>
                                <td>  0.78-1.58  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td colspan="2">
                                    <bold>Relationship status</bold>
                                </td>
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td />
                                <td>  In relationship (ref.)  </td>
                                <td>  1.00  </td>
                                <td />
                                <td />
                                <td />
                                <td>  1.00  </td>
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td />
                                <td>  Single  </td>
                                <td>  1.10  </td>
                                <td>  .63  </td>
                                <td>  0.76-1.59  </td>
                                <td />
                                <td>  1.12  </td>
                                <td>  .55  </td>
                                <td>  0.77-1.65  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td />
                                <td>  <bold># persons in household</bold>  </td>
                                <td>  0.92  </td>
                                <td>  .11  </td>
                                <td>  0.82-1.02  </td>
                                <td />
                                <td>  0.90  </td>
                                <td>  .06  </td>
                                <td>  0.81-1.01  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td colspan="2">
                                    <bold>Native country</bold>
                                </td>
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td />
                                <td>  The Netherlands (ref.)  </td>
                                <td>  1.00  </td>
                                <td />
                                <td />
                                <td />
                                <td>  1.00  </td>
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td />
                                <td>  Other  </td>
                                <td>  1.78  </td>
                                <td>  .04  </td>
                                <td>  1.03-3.08  </td>
                                <td />
                                <td>  1.54  </td>
                                <td>  .14  </td>
                                <td>  0.87-2.70  </td>
                            </tr>
                            <tr valign="top">
                                <td colspan="3">
                                    <bold>
                                        <italic>Health status</italic>
                                    </bold>
                                </td>
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td colspan="2">
                                    <bold>BMI</bold>
                                </td>
                                <td>  1.00  </td>
                                <td>  .79  </td>
                                <td>  0.96-1.03  </td>
                                <td />
                                <td>  1.00  </td>
                                <td>  .82  </td>
                                <td>  0.96-1.03  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td />
                                <td>  <bold>Quality of Life</bold>  </td>
                                <td>  0.98  </td>
                                <td>  .35  </td>
                                <td>  0.95-1.02  </td>
                                <td />
                                <td>  0.98  </td>
                                <td>  .18  </td>
                                <td>  0.94-1.01  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td />
                                <td>  <bold>K10</bold>  </td>
                                <td>  1.00  </td>
                                <td>  .82  </td>
                                <td>  0.97-1.04  </td>
                                <td />
                                <td>  1.00  </td>
                                <td>  .87  </td>
                                <td>  0.96-1.03  </td>
                            </tr>
                            <tr valign="top">
                                <td colspan="3">
                                    <bold>
                                        <italic>Non-adherence to guidelines</italic>
                                    </bold>
                                </td>
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                                <td />
                            </tr>
                            <tr valign="top">
                                <td />
                                <td colspan="2">
                                    <bold>Number of guidelines</bold>
                                </td>
                                <td />
                                <td />
                                <td />
                                <td />
                                <td>  0.49  </td>
                                <td>  &#60; .001  </td>
                                <td>  0.42-0.58  </td>
                            </tr>
                            <tr valign="top">
                                <td />
                                <td />
                                <td>  Nagelkerke&#8217;s R<sup>2</sup>
                                </td>
                                <td />
                                <td />
                                <td>  .073  </td>
                                <td />
                                <td />
                                <td />
                                <td>  .151  </td>
                            </tr>
                        </tbody>
                    </table>
                    <table-wrap-foot>
                        <fn id="table4fn1">
                            <p>
                                <sup>a</sup> Note: Respondents who did not want to report their income were classified in the category &#8220;&#8364; 1751 - &#8364; 3050&#8221;</p>
                        </fn>
                    </table-wrap-foot>
                </table-wrap>
            </sec>
        </sec>
        <sec sec-type="discussion">
            <title>Discussion</title>
            <p>In view of the high number of people with an unhealthy lifestyle, there is a widely recognized need for interventions to change multiple behaviors. However, the best strategy to deliver such web-based interventions remains unclear. Addressing multiple health behaviors in one intervention leads to more extensive programs, which require more time and effort from the respondents [eg, 31]. We compared dropout rates of a sequential and a simultaneous version of a computer-tailored intervention regarding physical activity, fruit consumption, vegetable consumption, alcohol intake, and smoking, and investigated the predictive value of personal characteristics and lifestyle behaviors on completion and dropout rates for the 2 strategies.</p>
            <p>Our first finding was that there were more non-completers in the simultaneous intervention than in the sequential intervention. The most important factor explaining the difference in dropout rate between these two conditions may be the difference in the length of the questionnaires and the computer-tailored advice that respondents received after the initial health risk appraisal. For example, if a respondent failed to adhere to 2 guidelines, the sequential intervention consisted of approximately 25 questions (average 10 minutes completion time), whereas the simultaneous intervention in such cases consisted of 50 questions, with an average completion time of 20 minutes. The advice also became twice as long, since the respondent had to fill in 2 modules in this case. Earlier research has also shown that the length of the program may be a primary reason to leave a website prematurely [<xref ref-type="bibr" rid="ref22">22</xref>]. Another possible reason may be information overload [<xref ref-type="bibr" rid="ref43">43</xref>]. Since each psychosocial construct is measured and tailored for each relevant behavior, this integrative approach is very demanding. An additional explanation that may need further research could be that in the simultaneous intervention, the 5 lifestyle modules had a predefined order, so respondents in this condition could not select the module they preferred to fill in first. Respondents in the sequential condition may have perceived more freedom of choice, since they could choose the lifestyle behavior about which they wanted to receive personal feedback. This hypothesis could be tested in follow-up studies, including qualitative interviews. </p>
            <p>Although the dropout rate was higher in the simultaneous intervention than in the sequential intervention, our findings revealed a high rate of non-completion in both types of intervention. One possible reason might be the recruitment strategy used. Completing the health risk appraisal took approximately 5 minutes in both conditions. The health risk appraisal was based on the <italic>Adult Health Monitor</italic> questionnaire that the respondents in our study had filled in at an earlier point in time. These respondents may not have wanted to make the effort of filling in a long questionnaire again. Hence, a considerable number of interested respondents of the potential target group may already have decided not to participate in the program after receiving the health risk appraisal. A second possible reason for the high dropout rate might be the study sample. Our study sample consisted of people from the general population, who were primarily invited simply to fill in a health-related questionnaire. Our study might have shown different results in terms of dropout rates in a group that would have been included based on their motivation to learn something about their lifestyle and/or to change lifestyle behaviors. This means that lack of motivation to change lifestyle may have been a reason for dropping out in both conditions [<xref ref-type="bibr" rid="ref56">56</xref>,<xref ref-type="bibr" rid="ref57">57</xref>]. Additionally, technical problems [<xref ref-type="bibr" rid="ref58">58</xref>,<xref ref-type="bibr" rid="ref59">59</xref>], e.g. disruption of the Internet connection or errors on the website, as well as problems navigating through the website, could have played a role &#8211; as was suggested by several e-mails received from respondents.</p>
            <p>In terms of personal characteristics that were predictive of completion or non-completion of the program, significant influences were found of age and gender. Older people and women were more likely to complete the program, which is in line with earlier findings [<xref ref-type="bibr" rid="ref25">25</xref>]. Furthermore, an unhealthy lifestyle was associated with higher dropout rates in both conditions. Earlier studies reported lower adherence to public health guidelines (ie, an unhealthier lifestyle) among people with a low socioeconomic status compared to people with a higher socioeconomic status [<xref ref-type="bibr" rid="ref60">60</xref>,<xref ref-type="bibr" rid="ref61">61</xref>], which means that this (high-risk) group in particular should be a target group for health promotion efforts. We found no difference in educational level, income, or employment status between respondents who dropped out at their first visit and those who did not. This is a relevant and promising finding, as it suggests that this tailored program is equally accepted and appreciated by both groups.</p>
            <p>Our findings &#8211; with dropout rates being higher in the simultaneous condition than in the sequential condition &#8211; suggest that a sequential tailoring strategy might be able to reach the largest group of participants. However, since approximately 60-70% of the population fails to adhere to multiple public health guidelines, people may need information about more than one lifestyle behavior. The sequential strategy used in our intervention may therefore be insufficient to meet the needs of a large part of the population, especially those of people who are interested in several health behaviors and who are motivated to change multiple lifestyle behaviors. In our sequential intervention, respondents received the health risk appraisal, including information about the 5 health behaviors. Yet respondents were limited to one single module in the second part of the program at their first visit. In the long term, this approach can be regarded as a multiple behavior change intervention using a sequential strategy, but in the short term, detailed information is made available about one behavior only. Since the dropout rate at the very first visit was high, future research should first concentrate on prolonged use (ie, continuing the intervention for a substantial period of time) and possible information overload. To date, it seems to be a challenge to hold respondents&#8217; attention in online interventions. Since the dropout rate even in the sequential condition is rather high, the number of psychosocial constructs as well as the tailored texts could be shortened, spread over time or delivered in different forms. Including more interactive elements, such as videos or games, may improve the attractiveness of eHealth programs, which in turn may result in longer visits [<xref ref-type="bibr" rid="ref62">62</xref>-<xref ref-type="bibr" rid="ref64">64</xref>]. Stimulating re-visits, which are necessary in our sequential approach, poses a second challenge for future research.</p>
            <p>The simultaneous tailoring strategy has advantages as well, insofar as people may receive tailored feedback on more than one lifestyle behavior at once. However, it may be better not to offer the modules in a predefined order. A study by Brouwer et al. [<xref ref-type="bibr" rid="ref25">25</xref>] shows that when people have a choice to select more than one behavior, they make use of this option and choose different behavior modules.</p>
            <p>Another option to explore is a mixture of both tailoring strategies, called preference-based tailoring [<xref ref-type="bibr" rid="ref39">39</xref>,<xref ref-type="bibr" rid="ref65">65</xref>] in which respondents can select the behavior modules which they want to fill in (not limited to only one module). This may make respondents perceive a higher level of autonomy [<xref ref-type="bibr" rid="ref66">66</xref>,<xref ref-type="bibr" rid="ref67">67</xref>] since they would not have to limit themselves to one single behavior at first, and could receive as much information as they wish.</p>
            <sec>
                <title>Strengths, Limitations, and Recommendations</title>
                <p>To our knowledge, this is the first study to compare sequential and simultaneous interventions addressing the 5 lifestyle behaviors of physical activity, fruit consumption, vegetable consumption, alcohol intake, and smoking, in terms of dropout rates. The study has yielded new information about predictors of completion of the 2 intervention types.</p>
                <p>The findings of this study should be interpreted keeping several limitations in mind. Our findings were based on self-reports, which could have led to recall bias (e.g., the high proportion of people who reported to meet the physical activity guideline may represent an overestimation of their actual level of physical activity); and the amounts of variance explained by our regression models were relatively low, indicating that other factors might play a role in determining program completion. Future research is necessary to identify additional relevant factors, for example, motivation to change, available time, interest in the topic, program evaluation (in terms of, eg, user-friendliness and attractiveness), and expectations from the program.</p>
                <p>The present study provides initial evidence for higher attrition rates in the simultaneous intervention strategy. Although this is likely to result in lower effectiveness of this intervention, future studies need to address the relative efficacy and effectiveness of simultaneous versus sequential tailoring. Hence, re-visiting rates for the two types of interventions should be compared, and the differences in effectiveness in terms of successful behavior change should be tested. It is imaginable that despite the higher dropout in the simultaneous condition, more respondents in this condition received all relevant information compared to those in the single/sequential condition who possibly only read information about the most preferred behavior module and/or never return to the intervention program. More research remains to be done to study in which condition more modules are opened and/or completed by the respondents during the duration of the project.</p>
            </sec>
            <sec>
                <title>Conclusions</title>
                <p>Our findings indicate a high rate of non-completion in both types of intervention, with more incompletes in the simultaneous intervention and among respondents with unhealthier lifestyles. In both conditions, discontinuation of the program was related to a younger age of the respondent, and in the sequential condition, being male was also associated with non-completion of the program. The results of this study suggest opportunities for optimizing online tailored lifestyle interventions: such programs should be tailored to all individual users; their efficiency should be improved; their attractiveness should be enhanced by integrating interactive elements; and their content and length or duration should be balanced.</p>
            </sec>
        </sec>
    </body>
    <back>
        <app-group>
            <app id="app1">
                <title>Multimedia Appendix 1</title>
                <p>CONSORT EHEALTH checklist V1.6 [<xref ref-type="bibr" rid="ref68">68</xref>].</p>
                <media xlink:href="jmir_v14i2e26_app1.pdf" xlink:title="PDF File (Adobe PDF File), 807KB" />
            </app>
        </app-group>
        <ack>
            <p>This study was funded by ZonMw, the Netherlands Organization for Health Research and Development (grant number: 120610012). Intervention development and implementation took place at Maastricht University. Data collection and data analysis were done in collaboration with the Regional Health Authorities of the Dutch provinces of North-Brabant (<italic>GGD Brabant-Zuidoost; GGD Hart voor Brabant; and GGD West-Brabant</italic>) and Zeeland (<italic>GGD Zeeland</italic>).</p>
        </ack>
        <fn-group>
            <fn fn-type="conflict">
                <p>Hein de Vries is the scientific director of Vision2Health, a company that licenses evidence-based innovative computer-tailored health communication tools. No other authors reported conflicts of interest.</p>
            </fn>
        </fn-group>
        <ref-list>
            <ref id="ref1">
                <label>1</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Orleans</surname>
                            <given-names>CT</given-names>
                        </name>
                    </person-group>
                    <article-title>Addressing multiple behavioral health risks in primary care. Broadening the focus of health behavior change research and practice</article-title>
                    <source>Am J Prev Med</source>
                    <year>2004</year>
                    <month>08</month>
                    <volume>27</volume>
                    <issue>2 Suppl</issue>
                    <fpage>1</fpage>
                    <lpage>3</lpage>
                    <pub-id pub-id-type="doi">10.1016/j.amepre.2004.05.001</pub-id>
                    <pub-id pub-id-type="medline">15275668</pub-id>
                    <pub-id pub-id-type="pii">S0749379704001084</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref2">
                <label>2</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Pronk</surname>
                            <given-names>NP</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Peek</surname>
                            <given-names>CJ</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Goldstein</surname>
                            <given-names>MG</given-names>
                        </name>
                    </person-group>
                    <article-title>Addressing multiple behavioral risk factors in primary care. A synthesis of current knowledge and stakeholder dialogue sessions</article-title>
                    <source>Am J Prev Med</source>
                    <year>2004</year>
                    <month>08</month>
                    <volume>27</volume>
                    <issue>2 Suppl</issue>
                    <fpage>4</fpage>
                    <lpage>17</lpage>
                    <pub-id pub-id-type="doi">10.1016/j.amepre.2004.04.024</pub-id>
                    <pub-id pub-id-type="medline">15275669</pub-id>
                    <pub-id pub-id-type="pii">S0749379704001047</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref3">
                <label>3</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Strecher</surname>
                            <given-names>V</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Wang</surname>
                            <given-names>C</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Derry</surname>
                            <given-names>H</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Wildenhaus</surname>
                            <given-names>K</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Johnson</surname>
                            <given-names>C</given-names>
                        </name>
                    </person-group>
                    <article-title>Tailored interventions for multiple risk behaviors</article-title>
                    <source>Health Educ Res</source>
                    <year>2002</year>
                    <month>10</month>
                    <volume>17</volume>
                    <issue>5</issue>
                    <fpage>619</fpage>
                    <lpage>26</lpage>
                    <comment>
                        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://her.oxfordjournals.org/cgi/pmidlookup?view=long&#38;pmid=12408206" />
                    </comment>
                    <pub-id pub-id-type="medline">12408206</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref4">
                <label>4</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>de Vries</surname>
                            <given-names>H</given-names>
                        </name>
                        <name name-style="western">
                            <surname>van 't Riet</surname>
                            <given-names>J</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Spigt</surname>
                            <given-names>M</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Metsemakers</surname>
                            <given-names>J</given-names>
                        </name>
                        <name name-style="western">
                            <surname>van den Akker</surname>
                            <given-names>M</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Vermunt</surname>
                            <given-names>JK</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Kremers</surname>
                            <given-names>S</given-names>
                        </name>
                    </person-group>
                    <article-title>Clusters of lifestyle behaviors: results from the Dutch SMILE study</article-title>
                    <source>Prev Med</source>
                    <year>2008</year>
                    <month>03</month>
                    <volume>46</volume>
                    <issue>3</issue>
                    <fpage>203</fpage>
                    <lpage>8</lpage>
                    <pub-id pub-id-type="doi">10.1016/j.ypmed.2007.08.005</pub-id>
                    <pub-id pub-id-type="medline">17904212</pub-id>
                    <pub-id pub-id-type="pii">S0091-7435(07)00369-6</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref5">
                <label>5</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Ezzati</surname>
                            <given-names>M</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Lopez</surname>
                            <given-names>AD</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Rodgers</surname>
                            <given-names>A</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Vander Hoorn</surname>
                            <given-names>S</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Murray</surname>
                            <given-names>CJ</given-names>
                        </name>
                        <collab>Comparative Risk Assessment Collaborating Group</collab>
                    </person-group>
                    <article-title>Selected major risk factors and global and regional burden of disease</article-title>
                    <source>Lancet</source>
                    <year>2002</year>
                    <month>11</month>
                    <day>2</day>
                    <volume>360</volume>
                    <issue>9343</issue>
                    <fpage>1347</fpage>
                    <lpage>60</lpage>
                    <pub-id pub-id-type="doi">10.1016/S0140-6736(02)11403-6</pub-id>
                    <pub-id pub-id-type="medline">12423980</pub-id>
                    <pub-id pub-id-type="pii">S0140-6736(02)11403-6</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref6">
                <label>6</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Riper</surname>
                            <given-names>H</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Kramer</surname>
                            <given-names>J</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Smit</surname>
                            <given-names>F</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Conijn</surname>
                            <given-names>B</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Schippers</surname>
                            <given-names>G</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Cuijpers</surname>
                            <given-names>P</given-names>
                        </name>
                    </person-group>
                    <article-title>Web-based self-help for problem drinkers: a pragmatic randomized trial</article-title>
                    <source>Addiction</source>
                    <year>2008</year>
                    <month>02</month>
                    <volume>103</volume>
                    <issue>2</issue>
                    <fpage>218</fpage>
                    <lpage>27</lpage>
                    <pub-id pub-id-type="doi">10.1111/j.1360-0443.2007.02063.x</pub-id>
                    <pub-id pub-id-type="medline">18199300</pub-id>
                    <pub-id pub-id-type="pii">ADD2063</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref7">
                <label>7</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>de Vries</surname>
                            <given-names>H</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Brug</surname>
                            <given-names>J</given-names>
                        </name>
                    </person-group>
                    <article-title>Computer-tailored interventions motivating people to adopt health promoting behaviours: introduction to a new approach</article-title>
                    <source>Patient Educ Couns</source>
                    <year>1999</year>
                    <month>02</month>
                    <volume>36</volume>
                    <issue>2</issue>
                    <fpage>99</fpage>
                    <lpage>105</lpage>
                    <pub-id pub-id-type="medline">10223015</pub-id>
                    <pub-id pub-id-type="pii">S073839919800127X</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref8">
                <label>8</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Brug</surname>
                            <given-names>J</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Campbell</surname>
                            <given-names>M</given-names>
                        </name>
                        <name name-style="western">
                            <surname>van Assema</surname>
                            <given-names>P</given-names>
                        </name>
                    </person-group>
                    <article-title>The application and impact of computer-generated personalized nutrition education: a review of the literature</article-title>
                    <source>Patient Educ Couns</source>
                    <year>1999</year>
                    <month>02</month>
                    <volume>36</volume>
                    <issue>2</issue>
                    <fpage>145</fpage>
                    <lpage>56</lpage>
                    <pub-id pub-id-type="medline">10223019</pub-id>
                    <pub-id pub-id-type="pii">S0738-3991(98)00131-1</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref9">
                <label>9</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Campbell</surname>
                            <given-names>MK</given-names>
                        </name>
                        <name name-style="western">
                            <surname>DeVellis</surname>
                            <given-names>BM</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Strecher</surname>
                            <given-names>VJ</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Ammerman</surname>
                            <given-names>AS</given-names>
                        </name>
                        <name name-style="western">
                            <surname>DeVellis</surname>
                            <given-names>RF</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Sandler</surname>
                            <given-names>RS</given-names>
                        </name>
                    </person-group>
                    <article-title>Improving dietary behavior: the effectiveness of tailored messages in primary care settings</article-title>
                    <source>Am J Public Health</source>
                    <year>1994</year>
                    <month>05</month>
                    <volume>84</volume>
                    <issue>5</issue>
                    <fpage>783</fpage>
                    <lpage>7</lpage>
                    <pub-id pub-id-type="medline">8179049</pub-id>
                    <pub-id pub-id-type="pmcid">PMC1615043</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref10">
                <label>10</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Krebs</surname>
                            <given-names>P</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Prochaska</surname>
                            <given-names>JO</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Rossi</surname>
                            <given-names>JS</given-names>
                        </name>
                    </person-group>
                    <article-title>A meta-analysis of computer-tailored interventions for health behavior change</article-title>
                    <source>Prev Med</source>
                    <year>2010</year>
                    <volume>51</volume>
                    <issue>3-4</issue>
                    <fpage>214</fpage>
                    <lpage>21</lpage>
                    <pub-id pub-id-type="doi">10.1016/j.ypmed.2010.06.004</pub-id>
                    <pub-id pub-id-type="medline">20558196</pub-id>
                    <pub-id pub-id-type="pii">S0091-7435(10)00231-8</pub-id>
                    <pub-id pub-id-type="pmcid">PMC2939185</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref11">
                <label>11</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Kreuter</surname>
                            <given-names>MW</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Oswald</surname>
                            <given-names>DL</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Bull</surname>
                            <given-names>FC</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Clark</surname>
                            <given-names>EM</given-names>
                        </name>
                    </person-group>
                    <article-title>Are tailored health education materials always more effective than non-tailored materials?</article-title>
                    <source>Health Educ Res</source>
                    <year>2000</year>
                    <month>06</month>
                    <volume>15</volume>
                    <issue>3</issue>
                    <fpage>305</fpage>
                    <lpage>15</lpage>
                    <comment>
                        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://her.oxfordjournals.org/cgi/pmidlookup?view=long&#38;pmid=10977378" />
                    </comment>
                    <pub-id pub-id-type="medline">10977378</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref12">
                <label>12</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Ruiter</surname>
                            <given-names>RA</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Kessels</surname>
                            <given-names>LT</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Jansma</surname>
                            <given-names>BM</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Brug</surname>
                            <given-names>J</given-names>
                        </name>
                    </person-group>
                    <article-title>Increased attention for computer-tailored health communications: an event-related potential study</article-title>
                    <source>Health Psychol</source>
                    <year>2006</year>
                    <month>05</month>
                    <volume>25</volume>
                    <issue>3</issue>
                    <fpage>300</fpage>
                    <lpage>6</lpage>
                    <pub-id pub-id-type="doi">10.1037/0278-6133.25.3.300</pub-id>
                    <pub-id pub-id-type="medline">16719601</pub-id>
                    <pub-id pub-id-type="pii">2006-05891-006</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref13">
                <label>13</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Oenema</surname>
                            <given-names>A</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Tan</surname>
                            <given-names>F</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Brug</surname>
                            <given-names>J</given-names>
                        </name>
                    </person-group>
                    <article-title>Short-term efficacy of a web-based computer-tailored nutrition intervention: main effects and mediators</article-title>
                    <source>Ann Behav Med</source>
                    <year>2005</year>
                    <month>02</month>
                    <volume>29</volume>
                    <issue>1</issue>
                    <fpage>54</fpage>
                    <lpage>63</lpage>
                    <pub-id pub-id-type="doi">10.1207/s15324796abm2901_8</pub-id>
                    <pub-id pub-id-type="medline">15677301</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref14">
                <label>14</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Skinner</surname>
                            <given-names>CS</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Campbell</surname>
                            <given-names>MK</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Rimer</surname>
                            <given-names>BK</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Curry</surname>
                            <given-names>S</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Prochaska</surname>
                            <given-names>JO</given-names>
                        </name>
                    </person-group>
                    <article-title>How effective is tailored print communication?</article-title>
                    <source>Ann Behav Med</source>
                    <year>1999</year>
                    <volume>21</volume>
                    <issue>4</issue>
                    <fpage>290</fpage>
                    <lpage>8</lpage>
                    <pub-id pub-id-type="medline">10721435</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref15">
                <label>15</label>
                <nlm-citation citation-type="book">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Smeets</surname>
                            <given-names>T</given-names>
                        </name>
                    </person-group>
                    <source>Towards a Healthy Lifestyle: the Development and Evaluation of a Computer-Tailored Lifestyle Intervention</source>
                    <year>2006</year>
                    <publisher-loc>Maastricht</publisher-loc>
                    <publisher-name>PhD thesis Maastricht University</publisher-name>
                </nlm-citation>
            </ref>
            <ref id="ref16">
                <label>16</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Spittaels</surname>
                            <given-names>H</given-names>
                        </name>
                        <name name-style="western">
                            <surname>de Bourdeaudhuij</surname>
                            <given-names>I</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Brug</surname>
                            <given-names>J</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Vandelanotte</surname>
                            <given-names>C</given-names>
                        </name>
                    </person-group>
                    <article-title>Effectiveness of an online computer-tailored physical activity intervention in a real-life setting</article-title>
                    <source>Health Educ Res</source>
                    <year>2007</year>
                    <month>06</month>
                    <volume>22</volume>
                    <issue>3</issue>
                    <fpage>385</fpage>
                    <lpage>96</lpage>
                    <comment>
                        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://her.oxfordjournals.org/cgi/pmidlookup?view=long&#38;pmid=16971674" />
                    </comment>
                    <pub-id pub-id-type="doi">10.1093/her/cyl096</pub-id>
                    <pub-id pub-id-type="medline">16971674</pub-id>
                    <pub-id pub-id-type="pii">cyl096</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref17">
                <label>17</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Abrams</surname>
                            <given-names>DB</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Orleans</surname>
                            <given-names>CT</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Niaura</surname>
                            <given-names>RS</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Goldstein</surname>
                            <given-names>MG</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Prochaska</surname>
                            <given-names>JO</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Velicer</surname>
                            <given-names>W</given-names>
                        </name>
                    </person-group>
                    <article-title>Integrating individual and public health perspectives for treatment of tobacco dependence under managed health care: a combined stepped-care and matching model</article-title>
                    <source>Ann Behav Med</source>
                    <year>1996</year>
                    <volume>18</volume>
                    <issue>4</issue>
                    <fpage>290</fpage>
                    <lpage>304</lpage>
                    <pub-id pub-id-type="doi">10.1007/BF02895291</pub-id>
                    <pub-id pub-id-type="medline">18425675</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref18">
                <label>18</label>
                <nlm-citation citation-type="web">
                    <person-group person-group-type="author">
                        <collab>Statistics Netherlands [Centraal Bureau voor de Statistiek]</collab>
                    </person-group>
                    <source>ICT gebruik van huishoudens naar huishoudkenmerken [ICT use of households by household characteristics]</source>
                    <access-date>2011-10-13</access-date>
                    <comment>2011<ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://statline.cbs.nl/StatWeb/publication/?VW=T&#38;DM=SLNL&#38;PA=71102ned&#38;D1=a&#38;D2=0&#38;D3=(l-11)-l&#38;HD=080901-1401">http://statline.cbs.nl/StatWeb/publication/?VW=T&#38;DM=SLNL&#38;PA=71102ned&#38;D1=a&#38;D2=0&#38;D3=(l-11)-l&#38;HD=080901-1401</ext-link>
                    </comment>
                    <pub-id pub-id-type="other">62OpQjsDy</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref19">
                <label>19</label>
                <nlm-citation citation-type="book">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>de Nooijer</surname>
                            <given-names>J</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Oenema</surname>
                            <given-names>A</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Kloek</surname>
                            <given-names>G</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Brug</surname>
                            <given-names>H</given-names>
                        </name>
                        <name name-style="western">
                            <surname>de Vries</surname>
                            <given-names>H</given-names>
                        </name>
                    </person-group>
                    <source>Bevordering van gezond gedrag via het internet: nu en in de toekomst [Promotion of healthy behavior through the Internet: Now and in the future]</source>
                    <year>2005</year>
                    <publisher-loc>Rotterdam</publisher-loc>
                    <publisher-name>Optima Grafische Communicatie</publisher-name>
                </nlm-citation>
            </ref>
            <ref id="ref20">
                <label>20</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Glasgow</surname>
                            <given-names>RE</given-names>
                        </name>
                    </person-group>
                    <article-title>eHealth evaluation and dissemination research</article-title>
                    <source>Am J Prev Med</source>
                    <year>2007</year>
                    <month>05</month>
                    <volume>32</volume>
                    <issue>5 Suppl</issue>
                    <fpage>S119</fpage>
                    <lpage>26</lpage>
                    <pub-id pub-id-type="doi">10.1016/j.amepre.2007.01.023</pub-id>
                    <pub-id pub-id-type="medline">17466816</pub-id>
                    <pub-id pub-id-type="pii">S0749-3797(07)00052-9</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref21">
                <label>21</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Leslie</surname>
                            <given-names>E</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Marshall</surname>
                            <given-names>AL</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Owen</surname>
                            <given-names>N</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Bauman</surname>
                            <given-names>A</given-names>
                        </name>
                    </person-group>
                    <article-title>Engagement and retention of participants in a physical activity website</article-title>
                    <source>Prev Med</source>
                    <year>2005</year>
                    <month>01</month>
                    <volume>40</volume>
                    <issue>1</issue>
                    <fpage>54</fpage>
                    <lpage>9</lpage>
                    <pub-id pub-id-type="doi">10.1016/j.ypmed.2004.05.002</pub-id>
                    <pub-id pub-id-type="medline">15530581</pub-id>
                    <pub-id pub-id-type="pii">S0091743504002701</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref22">
                <label>22</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Brouwer</surname>
                            <given-names>W</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Oenema</surname>
                            <given-names>A</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Crutzen</surname>
                            <given-names>R</given-names>
                        </name>
                        <name name-style="western">
                            <surname>de Nooijer</surname>
                            <given-names>J</given-names>
                        </name>
                        <name name-style="western">
                            <surname>de Vries</surname>
                            <given-names>N</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Brug</surname>
                            <given-names>J</given-names>
                        </name>
                    </person-group>
                    <article-title>What makes people decide to visit and use an internet-delivered behavior-change intervention?</article-title>
                    <source>Health Education</source>
                    <year>2009</year>
                    <volume>109</volume>
                    <fpage>460</fpage>
                    <lpage>473</lpage>
                    <pub-id pub-id-type="doi">10.1108/09654280911001149</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref23">
                <label>23</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Evers</surname>
                            <given-names>KE</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Cummins</surname>
                            <given-names>CO</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Prochaska</surname>
                            <given-names>JO</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Prochaska</surname>
                            <given-names>JM</given-names>
                        </name>
                    </person-group>
                    <article-title>Online health behavior and disease management programs: are we ready for them? Are they ready for us?</article-title>
                    <source>J Med Internet Res</source>
                    <year>2005</year>
                    <month>07</month>
                    <day>1</day>
                    <volume>7</volume>
                    <issue>3</issue>
                    <fpage>e27</fpage>
                    <comment>
                        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://www.jmir.org/2005/3/e27/" />
                    </comment>
                    <pub-id pub-id-type="doi">10.2196/jmir.7.3.e27</pub-id>
                    <pub-id pub-id-type="medline">15998618</pub-id>
                    <pub-id pub-id-type="pii">v7i3e27</pub-id>
                    <pub-id pub-id-type="pmcid">PMC1550656</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref24">
                <label>24</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Glasgow</surname>
                            <given-names>RE</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Nelson</surname>
                            <given-names>CC</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Kearney</surname>
                            <given-names>KA</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Reid</surname>
                            <given-names>R</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Ritzwoller</surname>
                            <given-names>DP</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Strecher</surname>
                            <given-names>VJ</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Couper</surname>
                            <given-names>MP</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Green</surname>
                            <given-names>B</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Wildenhaus</surname>
                            <given-names>K</given-names>
                        </name>
                    </person-group>
                    <article-title>Reach, engagement, and retention in an Internet-based weight loss program in a multi-site randomized controlled trial</article-title>
                    <source>J Med Internet Res</source>
                    <year>2007</year>
                    <volume>9</volume>
                    <issue>2</issue>
                    <fpage>e11</fpage>
                    <comment>
                        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://www.jmir.org/2007/2/e11/" />
                    </comment>
                    <pub-id pub-id-type="doi">10.2196/jmir.9.2.e11</pub-id>
                    <pub-id pub-id-type="medline">17513282</pub-id>
                    <pub-id pub-id-type="pii">v9i2e11</pub-id>
                    <pub-id pub-id-type="pmcid">PMC1874718</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref25">
                <label>25</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Brouwer</surname>
                            <given-names>W</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Oenema</surname>
                            <given-names>A</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Raat</surname>
                            <given-names>H</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Crutzen</surname>
                            <given-names>R</given-names>
                        </name>
                        <name name-style="western">
                            <surname>de Nooijer</surname>
                            <given-names>J</given-names>
                        </name>
                        <name name-style="western">
                            <surname>de Vries</surname>
                            <given-names>NK</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Brug</surname>
                            <given-names>J</given-names>
                        </name>
                    </person-group>
                    <article-title>Characteristics of visitors and revisitors to an Internet-delivered computer-tailored lifestyle intervention implemented for use by the general public</article-title>
                    <source>Health Educ Res</source>
                    <year>2010</year>
                    <month>08</month>
                    <volume>25</volume>
                    <issue>4</issue>
                    <fpage>585</fpage>
                    <lpage>95</lpage>
                    <comment>
                        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://her.oxfordjournals.org/cgi/pmidlookup?view=long&#38;pmid=19897515" />
                    </comment>
                    <pub-id pub-id-type="doi">10.1093/her/cyp063</pub-id>
                    <pub-id pub-id-type="medline">19897515</pub-id>
                    <pub-id pub-id-type="pii">cyp063</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref26">
                <label>26</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Spring</surname>
                            <given-names>B</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Pagoto</surname>
                            <given-names>S</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Pingitore</surname>
                            <given-names>R</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Doran</surname>
                            <given-names>N</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Schneider</surname>
                            <given-names>K</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Hedeker</surname>
                            <given-names>D</given-names>
                        </name>
                    </person-group>
                    <article-title>Randomized controlled trial for behavioral smoking and weight control treatment: effect of concurrent versus sequential intervention</article-title>
                    <source>J Consult Clin Psychol</source>
                    <year>2004</year>
                    <month>10</month>
                    <volume>72</volume>
                    <issue>5</issue>
                    <fpage>785</fpage>
                    <lpage>96</lpage>
                    <pub-id pub-id-type="doi">10.1037/0022-006X.72.5.785</pub-id>
                    <pub-id pub-id-type="medline">15482037</pub-id>
                    <pub-id pub-id-type="pii">2004-19094-006</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref27">
                <label>27</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Hyman</surname>
                            <given-names>DJ</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Pavlik</surname>
                            <given-names>VN</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Taylor</surname>
                            <given-names>WC</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Goodrick</surname>
                            <given-names>GK</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Moye</surname>
                            <given-names>L</given-names>
                        </name>
                    </person-group>
                    <article-title>Simultaneous vs sequential counseling for multiple behavior change</article-title>
                    <source>Arch Intern Med</source>
                    <year>2007</year>
                    <month>06</month>
                    <day>11</day>
                    <volume>167</volume>
                    <issue>11</issue>
                    <fpage>1152</fpage>
                    <lpage>8</lpage>
                    <comment>
                        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://archinte.ama-assn.org/cgi/pmidlookup?view=long&#38;pmid=17563023" />
                    </comment>
                    <pub-id pub-id-type="doi">10.1001/archinte.167.11.1152</pub-id>
                    <pub-id pub-id-type="medline">17563023</pub-id>
                    <pub-id pub-id-type="pii">167/11/1152</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref28">
                <label>28</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Vandelanotte</surname>
                            <given-names>C</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Reeves</surname>
                            <given-names>MM</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Brug</surname>
                            <given-names>J</given-names>
                        </name>
                        <name name-style="western">
                            <surname>de Bourdeaudhuij</surname>
                            <given-names>I</given-names>
                        </name>
                    </person-group>
                    <article-title>A randomized trial of sequential and simultaneous multiple behavior change interventions for physical activity and fat intake</article-title>
                    <source>Prev Med</source>
                    <year>2008</year>
                    <month>03</month>
                    <volume>46</volume>
                    <issue>3</issue>
                    <fpage>232</fpage>
                    <lpage>7</lpage>
                    <pub-id pub-id-type="doi">10.1016/j.ypmed.2007.07.008</pub-id>
                    <pub-id pub-id-type="medline">17707079</pub-id>
                    <pub-id pub-id-type="pii">S0091-7435(07)00299-X</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref29">
                <label>29</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Glasgow</surname>
                            <given-names>RE</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Goldstein</surname>
                            <given-names>MG</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Ockene</surname>
                            <given-names>JK</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Pronk</surname>
                            <given-names>NP</given-names>
                        </name>
                    </person-group>
                    <article-title>Translating what we have learned into practice. Principles and hypotheses for interventions addressing multiple behaviors in primary care</article-title>
                    <source>Am J Prev Med</source>
                    <year>2004</year>
                    <month>08</month>
                    <volume>27</volume>
                    <issue>2 Suppl</issue>
                    <fpage>88</fpage>
                    <lpage>101</lpage>
                    <pub-id pub-id-type="doi">10.1016/j.amepre.2004.04.019</pub-id>
                    <pub-id pub-id-type="medline">15275677</pub-id>
                    <pub-id pub-id-type="pii">S0749379704000996</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref30">
                <label>30</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Strecher</surname>
                            <given-names>VJ</given-names>
                        </name>
                        <name name-style="western">
                            <surname>McClure</surname>
                            <given-names>J</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Alexander</surname>
                            <given-names>G</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Chakraborty</surname>
                            <given-names>B</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Nair</surname>
                            <given-names>V</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Konkel</surname>
                            <given-names>J</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Greene</surname>
                            <given-names>S</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Couper</surname>
                            <given-names>M</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Carlier</surname>
                            <given-names>C</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Wiese</surname>
                            <given-names>C</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Little</surname>
                            <given-names>R</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Pomerleau</surname>
                            <given-names>C</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Pomerleau</surname>
                            <given-names>O</given-names>
                        </name>
                    </person-group>
                    <article-title>The role of engagement in a tailored web-based smoking cessation program: randomized controlled trial</article-title>
                    <source>J Med Internet Res</source>
                    <year>2008</year>
                    <volume>10</volume>
                    <issue>5</issue>
                    <fpage>e36</fpage>
                    <comment>
                        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://www.jmir.org/2008/5/e36/" />
                    </comment>
                    <pub-id pub-id-type="doi">10.2196/jmir.1002</pub-id>
                    <pub-id pub-id-type="medline">18984557</pub-id>
                    <pub-id pub-id-type="pii">v10i5e36</pub-id>
                    <pub-id pub-id-type="pmcid">PMC2630833</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref31">
                <label>31</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Prochaska</surname>
                            <given-names>JJ</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Spring</surname>
                            <given-names>B</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Nigg</surname>
                            <given-names>CR</given-names>
                        </name>
                    </person-group>
                    <article-title>Multiple health behavior change research: an introduction and overview</article-title>
                    <source>Prev Med</source>
                    <year>2008</year>
                    <month>03</month>
                    <volume>46</volume>
                    <issue>3</issue>
                    <fpage>181</fpage>
                    <lpage>8</lpage>
                    <pub-id pub-id-type="doi">10.1016/j.ypmed.2008.02.001</pub-id>
                    <pub-id pub-id-type="medline">18319098</pub-id>
                    <pub-id pub-id-type="pii">S0091-7435(08)00052-2</pub-id>
                    <pub-id pub-id-type="pmcid">PMC2288583</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref32">
                <label>32</label>
                <nlm-citation citation-type="book">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Meichenbaum</surname>
                            <given-names>D</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Turk</surname>
                            <given-names>DC</given-names>
                        </name>
                    </person-group>
                    <source>Facilitating treatment adherence: a practitioner&#039;s guidebook</source>
                    <year>1987</year>
                    <publisher-loc>New York</publisher-loc>
                    <publisher-name>Plenum Press</publisher-name>
                </nlm-citation>
            </ref>
            <ref id="ref33">
                <label>33</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Baumeister</surname>
                            <given-names>RF</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Bratslavsky</surname>
                            <given-names>E</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Muraven</surname>
                            <given-names>M</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Tice</surname>
                            <given-names>DM</given-names>
                        </name>
                    </person-group>
                    <article-title>Ego depletion: is the active self a limited resource?</article-title>
                    <source>J Pers Soc Psychol</source>
                    <year>1998</year>
                    <month>05</month>
                    <volume>74</volume>
                    <issue>5</issue>
                    <fpage>1252</fpage>
                    <lpage>65</lpage>
                    <pub-id pub-id-type="medline">9599441</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref34">
                <label>34</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Hagger</surname>
                            <given-names>MS</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Wood</surname>
                            <given-names>C</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Stiff</surname>
                            <given-names>C</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Chatzisarantis</surname>
                            <given-names>NL</given-names>
                        </name>
                    </person-group>
                    <article-title>Ego depletion and the strength model of self-control: a meta-analysis</article-title>
                    <source>Psychol Bull</source>
                    <year>2010</year>
                    <month>07</month>
                    <volume>136</volume>
                    <issue>4</issue>
                    <fpage>495</fpage>
                    <lpage>525</lpage>
                    <pub-id pub-id-type="doi">10.1037/a0019486</pub-id>
                    <pub-id pub-id-type="medline">20565167</pub-id>
                    <pub-id pub-id-type="pii">2010-12718-004</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref35">
                <label>35</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Taylor</surname>
                            <given-names>WC</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Hepworth</surname>
                            <given-names>JT</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Lees</surname>
                            <given-names>E</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Cassells</surname>
                            <given-names>A</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Gousse</surname>
                            <given-names>Y</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Sweeney</surname>
                            <given-names>MM</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Vaughn</surname>
                            <given-names>A</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Tobin</surname>
                            <given-names>JN</given-names>
                        </name>
                    </person-group>
                    <article-title>Readiness to change physical activity and dietary practices and willingness to consult healthcare providers</article-title>
                    <source>Health Res Policy Syst</source>
                    <year>2004</year>
                    <month>06</month>
                    <day>10</day>
                    <volume>2</volume>
                    <issue>1</issue>
                    <fpage>2</fpage>
                    <comment>
                        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://www.health-policy-systems.com/content/2/1/2" />
                    </comment>
                    <pub-id pub-id-type="doi">10.1186/1478-4505-2-2</pub-id>
                    <pub-id pub-id-type="medline">15191611</pub-id>
                    <pub-id pub-id-type="pii">1478-4505-2-2</pub-id>
                    <pub-id pub-id-type="pmcid">PMC446216</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref36">
                <label>36</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Dunn</surname>
                            <given-names>CL</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Hannan</surname>
                            <given-names>PJ</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Jeffery</surname>
                            <given-names>RW</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Sherwood</surname>
                            <given-names>NE</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Pronk</surname>
                            <given-names>NP</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Boyle</surname>
                            <given-names>R</given-names>
                        </name>
                    </person-group>
                    <article-title>The comparative and cumulative effects of a dietary restriction and exercise on weight loss</article-title>
                    <source>Int J Obes (Lond)</source>
                    <year>2006</year>
                    <month>01</month>
                    <volume>30</volume>
                    <issue>1</issue>
                    <fpage>112</fpage>
                    <lpage>21</lpage>
                    <pub-id pub-id-type="doi">10.1038/sj.ijo.0803046</pub-id>
                    <pub-id pub-id-type="medline">16231038</pub-id>
                    <pub-id pub-id-type="pii">0803046</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref37">
                <label>37</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Jakicic</surname>
                            <given-names>JM</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Wing</surname>
                            <given-names>RR</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Winters-Hart</surname>
                            <given-names>C</given-names>
                        </name>
                    </person-group>
                    <article-title>Relationship of physical activity to eating behaviors and weight loss in women</article-title>
                    <source>Med Sci Sports Exerc</source>
                    <year>2002</year>
                    <month>10</month>
                    <volume>34</volume>
                    <issue>10</issue>
                    <fpage>1653</fpage>
                    <lpage>9</lpage>
                    <pub-id pub-id-type="doi">10.1249/01.MSS.0000031483.65271.FD</pub-id>
                    <pub-id pub-id-type="medline">12370568</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref38">
                <label>38</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Kremers</surname>
                            <given-names>SPJ</given-names>
                        </name>
                        <name name-style="western">
                            <surname>de Bruijn</surname>
                            <given-names>GJ</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Schaalma</surname>
                            <given-names>H</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Brug</surname>
                            <given-names>J</given-names>
                        </name>
                    </person-group>
                    <article-title>Clustering of energy balance-related behaviors and their intrapersonal determinants</article-title>
                    <source>Psychology &#38; Health</source>
                    <year>2004</year>
                    <volume>19</volume>
                    <fpage>595</fpage>
                    <lpage>606</lpage>
                    <pub-id pub-id-type="doi">10.1080/08870440412331279630</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref39">
                <label>39</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Kwak</surname>
                            <given-names>L</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Kremers</surname>
                            <given-names>SP</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Werkman</surname>
                            <given-names>A</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Visscher</surname>
                            <given-names>TL</given-names>
                        </name>
                        <name name-style="western">
                            <surname>van Baak</surname>
                            <given-names>MA</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Brug</surname>
                            <given-names>J</given-names>
                        </name>
                    </person-group>
                    <article-title>The NHF-NRG In Balance-project: the application of Intervention Mapping in the development, implementation and evaluation of weight gain prevention at the worksite</article-title>
                    <source>Obes Rev</source>
                    <year>2007</year>
                    <month>07</month>
                    <volume>8</volume>
                    <issue>4</issue>
                    <fpage>347</fpage>
                    <lpage>61</lpage>
                    <pub-id pub-id-type="doi">10.1111/j.1467-789X.2006.00304.x</pub-id>
                    <pub-id pub-id-type="medline">17578384</pub-id>
                    <pub-id pub-id-type="pii">OBR304</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref40">
                <label>40</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Mata</surname>
                            <given-names>J</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Silva</surname>
                            <given-names>MN</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Vieira</surname>
                            <given-names>PN</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Carra&#231;a</surname>
                            <given-names>EV</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Andrade</surname>
                            <given-names>AM</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Coutinho</surname>
                            <given-names>SR</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Sardinha</surname>
                            <given-names>LB</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Teixeira</surname>
                            <given-names>PJ</given-names>
                        </name>
                    </person-group>
                    <article-title>Motivational spill-over during weight control: increased self-determination and exercise intrinsic motivation predict eating self-regulation</article-title>
                    <source>Health Psychol</source>
                    <year>2009</year>
                    <month>11</month>
                    <volume>28</volume>
                    <issue>6</issue>
                    <fpage>709</fpage>
                    <lpage>16</lpage>
                    <pub-id pub-id-type="doi">10.1037/a0016764</pub-id>
                    <pub-id pub-id-type="medline">19916639</pub-id>
                    <pub-id pub-id-type="pii">2009-20990-008</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref41">
                <label>41</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Spittaels</surname>
                            <given-names>H</given-names>
                        </name>
                        <name name-style="western">
                            <surname>de Bourdeaudhuij</surname>
                            <given-names>I</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Vandelanotte</surname>
                            <given-names>C</given-names>
                        </name>
                    </person-group>
                    <article-title>Evaluation of a website-delivered computer-tailored intervention for increasing physical activity in the general population</article-title>
                    <source>Prev Med</source>
                    <year>2007</year>
                    <month>03</month>
                    <volume>44</volume>
                    <issue>3</issue>
                    <fpage>209</fpage>
                    <lpage>17</lpage>
                    <pub-id pub-id-type="doi">10.1016/j.ypmed.2006.11.010</pub-id>
                    <pub-id pub-id-type="medline">17197015</pub-id>
                    <pub-id pub-id-type="pii">S0091-7435(06)00502-0</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref42">
                <label>42</label>
                <nlm-citation citation-type="book">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Crutzen</surname>
                            <given-names>R</given-names>
                        </name>
                    </person-group>
                    <source>Hard to Get, Hard to Keep. Dissemination of and Exposure to Internet-Delivered Health Behavior Change Interventions Aimed at Adolescents</source>
                    <year>2009</year>
                    <publisher-loc>Maastricht</publisher-loc>
                    <publisher-name>PhD thesis Maastricht University</publisher-name>
                </nlm-citation>
            </ref>
            <ref id="ref43">
                <label>43</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Prochaska</surname>
                            <given-names>JO</given-names>
                        </name>
                    </person-group>
                    <article-title>Multiple Health Behavior Research represents the future of preventive medicine</article-title>
                    <source>Prev Med</source>
                    <year>2008</year>
                    <month>03</month>
                    <volume>46</volume>
                    <issue>3</issue>
                    <fpage>281</fpage>
                    <lpage>5</lpage>
                    <pub-id pub-id-type="doi">10.1016/j.ypmed.2008.01.015</pub-id>
                    <pub-id pub-id-type="medline">18319100</pub-id>
                    <pub-id pub-id-type="pii">S0091-7435(08)00061-3</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref44">
                <label>44</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Prochaska</surname>
                            <given-names>JJ</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Nigg</surname>
                            <given-names>CR</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Spring</surname>
                            <given-names>B</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Velicer</surname>
                            <given-names>WF</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Prochaska</surname>
                            <given-names>JO</given-names>
                        </name>
                    </person-group>
                    <article-title>The benefits and challenges of multiple health behavior change in research and in practice</article-title>
                    <source>Prev Med</source>
                    <year>2010</year>
                    <volume>50</volume>
                    <issue>1-2</issue>
                    <fpage>26</fpage>
                    <lpage>9</lpage>
                    <pub-id pub-id-type="doi">10.1016/j.ypmed.2009.11.009</pub-id>
                    <pub-id pub-id-type="medline">19948184</pub-id>
                    <pub-id pub-id-type="pii">S0091-7435(09)00595-7</pub-id>
                    <pub-id pub-id-type="pmcid">PMC2813890</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref45">
                <label>45</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Noar</surname>
                            <given-names>SM</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Chabot</surname>
                            <given-names>M</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Zimmerman</surname>
                            <given-names>RS</given-names>
                        </name>
                    </person-group>
                    <article-title>Applying health behavior theory to multiple behavior change: considerations and approaches</article-title>
                    <source>Prev Med</source>
                    <year>2008</year>
                    <month>03</month>
                    <volume>46</volume>
                    <issue>3</issue>
                    <fpage>275</fpage>
                    <lpage>80</lpage>
                    <pub-id pub-id-type="doi">10.1016/j.ypmed.2007.08.001</pub-id>
                    <pub-id pub-id-type="medline">17825898</pub-id>
                    <pub-id pub-id-type="pii">S0091-7435(07)00330-1</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref46">
                <label>46</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Schulz</surname>
                            <given-names>DN</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Kremers</surname>
                            <given-names>SP</given-names>
                        </name>
                        <name name-style="western">
                            <surname>van Osch</surname>
                            <given-names>LA</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Schneider</surname>
                            <given-names>F</given-names>
                        </name>
                        <name name-style="western">
                            <surname>van Adrichem</surname>
                            <given-names>MJ</given-names>
                        </name>
                        <name name-style="western">
                            <surname>de Vries</surname>
                            <given-names>H</given-names>
                        </name>
                    </person-group>
                    <article-title>Testing a Dutch web-based tailored lifestyle programme among adults: a study protocol</article-title>
                    <source>BMC Public Health</source>
                    <year>2011</year>
                    <volume>11</volume>
                    <fpage>108</fpage>
                    <comment>
                        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://www.biomedcentral.com/1471-2458/11/108" />
                    </comment>
                    <pub-id pub-id-type="doi">10.1186/1471-2458-11-108</pub-id>
                    <pub-id pub-id-type="medline">21324181</pub-id>
                    <pub-id pub-id-type="pii">1471-2458-11-108</pub-id>
                    <pub-id pub-id-type="pmcid">PMC3050747</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref47">
                <label>47</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>de Vries</surname>
                            <given-names>H</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Mudde</surname>
                            <given-names>A</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Leijs</surname>
                            <given-names>I</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Charlton</surname>
                            <given-names>A</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Vartiainen</surname>
                            <given-names>E</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Buijs</surname>
                            <given-names>G</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Clemente</surname>
                            <given-names>MP</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Storm</surname>
                            <given-names>H</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Gonz&#225;lez Navarro</surname>
                            <given-names>A</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Nebot</surname>
                            <given-names>M</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Prins</surname>
                            <given-names>T</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Kremers</surname>
                            <given-names>S</given-names>
                        </name>
                    </person-group>
                    <article-title>The European Smoking Prevention Framework Approach (EFSA): an example of integral prevention</article-title>
                    <source>Health Educ Res</source>
                    <year>2003</year>
                    <month>10</month>
                    <volume>18</volume>
                    <issue>5</issue>
                    <fpage>611</fpage>
                    <lpage>26</lpage>
                    <comment>
                        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://her.oxfordjournals.org/cgi/pmidlookup?view=long&#38;pmid=14572020" />
                    </comment>
                    <pub-id pub-id-type="medline">14572020</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref48">
                <label>48</label>
                <nlm-citation citation-type="book">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Ware</surname>
                            <given-names>JE</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Kosinski</surname>
                            <given-names>M</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Keller</surname>
                            <given-names>SD</given-names>
                        </name>
                    </person-group>
                    <source>SF-12: How to Score the SF-12 Physical and Mental Health Summary Scales</source>
                    <year>1995</year>
                    <publisher-loc>Boston</publisher-loc>
                    <publisher-name>The Health Institute, New England Medical Center</publisher-name>
                </nlm-citation>
            </ref>
            <ref id="ref49">
                <label>49</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Ware</surname>
                            <given-names>J</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Kosinski</surname>
                            <given-names>M</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Keller</surname>
                            <given-names>SD</given-names>
                        </name>
                    </person-group>
                    <article-title>A 12-Item Short-Form Health Survey: construction of scales and preliminary tests of reliability and validity</article-title>
                    <source>Med Care</source>
                    <year>1996</year>
                    <month>03</month>
                    <volume>34</volume>
                    <issue>3</issue>
                    <fpage>220</fpage>
                    <lpage>33</lpage>
                    <pub-id pub-id-type="medline">8628042</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref50">
                <label>50</label>
                <nlm-citation citation-type="book">
                    <person-group person-group-type="author">
                        <collab>Kessler</collab>
                        <collab>R</collab>
                        <collab>Mroczek</collab>
                        <collab>D</collab>
                    </person-group>
                    <source>Final Versions of our Non-Specific Psychological Distress Scale (memo dated 10/3/94)</source>
                    <year>1994</year>
                    <publisher-loc>Ann Arbor</publisher-loc>
                    <publisher-name>Survey Research Center of the Institute for Social Research, University of Michigan</publisher-name>
                </nlm-citation>
            </ref>
            <ref id="ref51">
                <label>51</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Wendel-Vos</surname>
                            <given-names>GC</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Schuit</surname>
                            <given-names>AJ</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Saris</surname>
                            <given-names>WH</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Kromhout</surname>
                            <given-names>D</given-names>
                        </name>
                    </person-group>
                    <article-title>Reproducibility and relative validity of the short questionnaire to assess health-enhancing physical activity</article-title>
                    <source>J Clin Epidemiol</source>
                    <year>2003</year>
                    <month>12</month>
                    <volume>56</volume>
                    <issue>12</issue>
                    <fpage>1163</fpage>
                    <lpage>9</lpage>
                    <pub-id pub-id-type="medline">14680666</pub-id>
                    <pub-id pub-id-type="pii">S0895435603002208</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref52">
                <label>52</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Ainsworth</surname>
                            <given-names>BE</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Haskell</surname>
                            <given-names>WL</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Whitt</surname>
                            <given-names>MC</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Irwin</surname>
                            <given-names>ML</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Swartz</surname>
                            <given-names>AM</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Strath</surname>
                            <given-names>SJ</given-names>
                        </name>
                        <name name-style="western">
                            <surname>O'Brien</surname>
                            <given-names>WL</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Bassett</surname>
                            <given-names>DR</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Schmitz</surname>
                            <given-names>KH</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Emplaincourt</surname>
                            <given-names>PO</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Jacobs</surname>
                            <given-names>DR</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Leon</surname>
                            <given-names>AS</given-names>
                        </name>
                    </person-group>
                    <article-title>Compendium of physical activities: an update of activity codes and MET intensities</article-title>
                    <source>Med Sci Sports Exerc</source>
                    <year>2000</year>
                    <month>09</month>
                    <volume>32</volume>
                    <issue>9 Suppl</issue>
                    <fpage>S498</fpage>
                    <lpage>504</lpage>
                    <pub-id pub-id-type="medline">10993420</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref53">
                <label>53</label>
                <nlm-citation citation-type="web">
                    <person-group person-group-type="author">
                        <collab>RIVM</collab>
                    </person-group>
                    <source>Lokale en nationale Monitor gezondheid. Indicatoren voor de Monitor Volksgezondheid [Local and national Health Monitor. Indicators of the Public Health Monitor]</source>
                    <access-date>2011-10-13</access-date>
                    <comment>2005<ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="https://www.monitorgezondheid.nl/volksindicatoren.aspx">https://www.monitorgezondheid.nl/volksindicatoren.aspx</ext-link>
                    </comment>
                    <pub-id pub-id-type="other">62OpsEkiG</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref54">
                <label>54</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Lemmens</surname>
                            <given-names>P</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Tan</surname>
                            <given-names>ES</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Knibbe</surname>
                            <given-names>RA</given-names>
                        </name>
                    </person-group>
                    <article-title>Measuring quantity and frequency of drinking in a general population survey: a comparison of five indices</article-title>
                    <source>J Stud Alcohol</source>
                    <year>1992</year>
                    <month>09</month>
                    <volume>53</volume>
                    <issue>5</issue>
                    <fpage>476</fpage>
                    <lpage>86</lpage>
                    <pub-id pub-id-type="medline">1405641</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref55">
                <label>55</label>
                <nlm-citation citation-type="book">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Cohen</surname>
                            <given-names>J</given-names>
                        </name>
                    </person-group>
                    <source>Statistical Power Analysis for the Behavioral Sciences (second ed.)</source>
                    <year>1988</year>
                    <publisher-loc>Hillsdale, N.J.</publisher-loc>
                    <publisher-name>L. Erlbaum Associates</publisher-name>
                </nlm-citation>
            </ref>
            <ref id="ref56">
                <label>56</label>
                <nlm-citation citation-type="book">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Brouwer</surname>
                            <given-names>W</given-names>
                        </name>
                    </person-group>
                    <source>Improving Exposure to Internet-Delivered Health Behavior Change Interventions. An Exploration of Determinants and Dissemination Strategies</source>
                    <year>2011</year>
                    <publisher-loc>Rotterdam</publisher-loc>
                    <publisher-name>PhD thesis, Erasmus Universiteit Rotterdam</publisher-name>
                </nlm-citation>
            </ref>
            <ref id="ref57">
                <label>57</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>van 't Riet</surname>
                            <given-names>J</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Crutzen</surname>
                            <given-names>R</given-names>
                        </name>
                        <name name-style="western">
                            <surname>de Vries</surname>
                            <given-names>H</given-names>
                        </name>
                    </person-group>
                    <article-title>Investigating predictors of visiting, using, and revisiting an online health-communication program: a longitudinal study</article-title>
                    <source>J Med Internet Res</source>
                    <year>2010</year>
                    <volume>12</volume>
                    <issue>3</issue>
                    <fpage>e37</fpage>
                    <comment>
                        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://www.jmir.org/2010/3/e37/" />
                    </comment>
                    <pub-id pub-id-type="doi">10.2196/jmir.1345</pub-id>
                    <pub-id pub-id-type="medline">20813716</pub-id>
                    <pub-id pub-id-type="pii">v12i3e37</pub-id>
                    <pub-id pub-id-type="pmcid">PMC2956328</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref58">
                <label>58</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Booth</surname>
                            <given-names>AO</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Nowson</surname>
                            <given-names>CA</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Matters</surname>
                            <given-names>H</given-names>
                        </name>
                    </person-group>
                    <article-title>Evaluation of an interactive, Internet-based weight loss program: a pilot study</article-title>
                    <source>Health Educ Res</source>
                    <year>2008</year>
                    <month>06</month>
                    <volume>23</volume>
                    <issue>3</issue>
                    <fpage>371</fpage>
                    <lpage>81</lpage>
                    <comment>
                        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://her.oxfordjournals.org/cgi/pmidlookup?view=long&#38;pmid=18349032" />
                    </comment>
                    <pub-id pub-id-type="doi">10.1093/her/cyn007</pub-id>
                    <pub-id pub-id-type="medline">18349032</pub-id>
                    <pub-id pub-id-type="pii">cyn007</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref59">
                <label>59</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Kypri</surname>
                            <given-names>K</given-names>
                        </name>
                        <name name-style="western">
                            <surname>McAnally</surname>
                            <given-names>HM</given-names>
                        </name>
                    </person-group>
                    <article-title>Randomized controlled trial of a web-based primary care intervention for multiple health risk behaviors</article-title>
                    <source>Prev Med</source>
                    <year>2005</year>
                    <volume>41</volume>
                    <issue>3-4</issue>
                    <fpage>761</fpage>
                    <lpage>6</lpage>
                    <pub-id pub-id-type="doi">10.1016/j.ypmed.2005.07.010</pub-id>
                    <pub-id pub-id-type="medline">16120456</pub-id>
                    <pub-id pub-id-type="pii">S0091-7435(05)00111-8</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref60">
                <label>60</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Harris</surname>
                            <given-names>JR</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Huang</surname>
                            <given-names>Y</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Hannon</surname>
                            <given-names>PA</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Williams</surname>
                            <given-names>B</given-names>
                        </name>
                    </person-group>
                    <article-title>Low-socioeconomic status workers: their health risks and how to reach them</article-title>
                    <source>J Occup Environ Med</source>
                    <year>2011</year>
                    <month>02</month>
                    <volume>53</volume>
                    <issue>2</issue>
                    <fpage>132</fpage>
                    <lpage>8</lpage>
                    <pub-id pub-id-type="doi">10.1097/JOM.0b013e3182045f2c</pub-id>
                    <pub-id pub-id-type="medline">21270663</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref61">
                <label>61</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Lampert</surname>
                            <given-names>T</given-names>
                        </name>
                    </person-group>
                    <article-title>Smoking, physical inactivity, and obesity: associations with social status</article-title>
                    <source>Dtsch Arztebl Int</source>
                    <year>2010</year>
                    <month>01</month>
                    <volume>107</volume>
                    <issue>1-2</issue>
                    <fpage>1</fpage>
                    <lpage>7</lpage>
                    <comment>
                        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://dx.doi.org/10.3238/arztebl.2010.0001" />
                    </comment>
                    <pub-id pub-id-type="doi">10.3238/arztebl.2010.0001</pub-id>
                    <pub-id pub-id-type="medline">20090874</pub-id>
                    <pub-id pub-id-type="pmcid">PMC2807643</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref62">
                <label>62</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Severson</surname>
                            <given-names>HH</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Gordon</surname>
                            <given-names>JS</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Danaher</surname>
                            <given-names>BG</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Akers</surname>
                            <given-names>L</given-names>
                        </name>
                    </person-group>
                    <article-title>ChewFree.com: evaluation of a Web-based cessation program for smokeless tobacco users</article-title>
                    <source>Nicotine Tob Res</source>
                    <year>2008</year>
                    <month>02</month>
                    <volume>10</volume>
                    <issue>2</issue>
                    <fpage>381</fpage>
                    <lpage>91</lpage>
                    <pub-id pub-id-type="doi">10.1080/14622200701824984</pub-id>
                    <pub-id pub-id-type="medline">18236303</pub-id>
                    <pub-id pub-id-type="pii">790122824</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref63">
                <label>63</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Stoddard</surname>
                            <given-names>JL</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Augustson</surname>
                            <given-names>EM</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Moser</surname>
                            <given-names>RP</given-names>
                        </name>
                    </person-group>
                    <article-title>Effect of adding a virtual community (bulletin board) to smokefree.gov: randomized controlled trial</article-title>
                    <source>J Med Internet Res</source>
                    <year>2008</year>
                    <volume>10</volume>
                    <issue>5</issue>
                    <fpage>e53</fpage>
                    <comment>
                        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://www.jmir.org/2008/5/e53/" />
                    </comment>
                    <pub-id pub-id-type="doi">10.2196/jmir.1124</pub-id>
                    <pub-id pub-id-type="medline">19097974</pub-id>
                    <pub-id pub-id-type="pii">v10i5e53</pub-id>
                    <pub-id pub-id-type="pmcid">PMC2630832</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref64">
                <label>64</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Vandelanotte</surname>
                            <given-names>C</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Mummery</surname>
                            <given-names>WK</given-names>
                        </name>
                    </person-group>
                    <article-title>Qualitative and quantitative research into the development and feasibility of a video-tailored physical activity intervention</article-title>
                    <source>Int J Behav Nutr Phys Act</source>
                    <year>2011</year>
                    <volume>8</volume>
                    <issue>1</issue>
                    <fpage>70</fpage>
                    <comment>
                        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://www.ijbnpa.org/content/8/1/70" />
                    </comment>
                    <pub-id pub-id-type="doi">10.1186/1479-5868-8-70</pub-id>
                    <pub-id pub-id-type="medline">21718546</pub-id>
                    <pub-id pub-id-type="pii">1479-5868-8-70</pub-id>
                    <pub-id pub-id-type="pmcid">PMC3141618</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref65">
                <label>65</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Kwak</surname>
                            <given-names>L</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Kremers</surname>
                            <given-names>SP</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Candel</surname>
                            <given-names>MJ</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Visscher</surname>
                            <given-names>TL</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Brug</surname>
                            <given-names>J</given-names>
                        </name>
                        <name name-style="western">
                            <surname>van Baak</surname>
                            <given-names>MA</given-names>
                        </name>
                    </person-group>
                    <article-title>Changes in skinfold thickness and waist circumference after 12 and 24 months resulting from the NHF-NRG In Balance-project</article-title>
                    <source>Int J Behav Nutr Phys Act</source>
                    <year>2010</year>
                    <volume>7</volume>
                    <fpage>26</fpage>
                    <comment>
                        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://www.ijbnpa.org/content/7//26" />
                    </comment>
                    <pub-id pub-id-type="doi">10.1186/1479-5868-7-26</pub-id>
                    <pub-id pub-id-type="medline">20370934</pub-id>
                    <pub-id pub-id-type="pii">1479-5868-7-26</pub-id>
                    <pub-id pub-id-type="pmcid">PMC2858095</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref66">
                <label>66</label>
                <nlm-citation citation-type="book">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Markland</surname>
                            <given-names>D</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Vansteenkiste</surname>
                            <given-names>M</given-names>
                        </name>
                    </person-group>
                    <person-group person-group-type="editor">
                        <name name-style="western">
                            <surname>Hagger</surname>
                            <given-names>MS</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Chatzisarantis</surname>
                            <given-names>NLD</given-names>
                        </name>
                    </person-group>
                    <article-title>Self determination theory and motivational interviewing in exercise</article-title>
                    <source>Intrinsic Motivation and Self-Determination in Exercise and Sport</source>
                    <year>2007</year>
                    <publisher-loc>Champaign, IL</publisher-loc>
                    <publisher-name>Human Kinetics</publisher-name>
                    <fpage>87</fpage>
                    <lpage>99</lpage>
                </nlm-citation>
            </ref>
            <ref id="ref67">
                <label>67</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Zuckerman</surname>
                            <given-names>M</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Porac</surname>
                            <given-names>J</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Lathin</surname>
                            <given-names>D</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Smith</surname>
                            <given-names>R</given-names>
                        </name>
                        <name name-style="western">
                            <surname>Deci</surname>
                            <given-names>EL</given-names>
                        </name>
                    </person-group>
                    <article-title>On the importance of self-determination for intrinsically motivated behavior</article-title>
                    <source>Personality and Social Psychology Bulletin</source>
                    <year>1978</year>
                    <volume>4</volume>
                    <fpage>443</fpage>
                    <lpage>6</lpage>
                    <pub-id pub-id-type="doi">10.1177/014616727800400317</pub-id>
                </nlm-citation>
            </ref>
            <ref id="ref68">
                <label>68</label>
                <nlm-citation citation-type="journal">
                    <person-group person-group-type="author">
                        <name name-style="western">
                            <surname>Eysenbach</surname>
                            <given-names>G</given-names>
                        </name>
                        <collab>CONSORT-EHEALTH Group</collab>
                    </person-group>
                    <article-title>CONSORT-EHEALTH: Improving and Standardizing Evaluation Reports of Web-based and Mobile Health Interventions</article-title>
                    <source>J Med Internet Res</source>
                    <year>2011</year>
                    <volume>13</volume>
                    <issue>4</issue>
                    <fpage>e126</fpage>
                    <comment>
                        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://www.jmir.org/2011/4/e126/" />
                    </comment>
                    <pub-id pub-id-type="doi">10.2196/jmir.1923</pub-id>
                    <pub-id pub-id-type="medline">22209829</pub-id>
                    <pub-id pub-id-type="pii">v13i4e126</pub-id>
                </nlm-citation>
            </ref>
        </ref-list>
    </back>
</article>